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Aaron E. Engelhart, Ph.D. - Publications

Affiliations: 
2002-2005 Chemistry and Biochemistry Arizona State University, Tempe, AZ, United States 
 2005-2010 Chemistry and Biochemistry Georgia Institute of Technology, Atlanta, GA 
 2011-2016 Harvard Medical School, Boston, MA, United States 
 2011-2016 Massachusetts General Hospital, Boston, MA 
Area:
Nucleic Acids
Website:
http://aaronengelhart.com/
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Heili JM, Stokes K, Gaut NJ, Deich C, Sharon J, Hoog T, Gomez-Garcia J, Cash B, Pawlak MR, Engelhart AE, Adamala KP. Controlled exchange of protein and nucleic acid signals from and between synthetic minimal cells. Cell Systems. 15: 49-62.e4. PMID 38237551 DOI: 10.1016/j.cels.2023.12.008  0.778
2023 Gehlbach EM, Robinson AO, Engelhart AE, Adamala KP. Sequential gentle hydration increases encapsulation in model protocells. Biorxiv : the Preprint Server For Biology. PMID 37873423 DOI: 10.1101/2023.10.15.562404  0.755
2023 Sato W, Rasmussen M, Gaut N, Devarajan M, Stokes K, Deich C, Engelhart AE, Adamala KP. A gene expression control technology for cell-free systems and synthetic cells via targeted gene silencing and transfection. Biotechnology and Bioengineering. PMID 37159417 DOI: 10.1002/bit.28422  0.77
2023 Sharon JA, Dasrath C, Fujiwara A, Snyder A, Blank M, O'Brien S, Aufdembrink LM, Engelhart AE, Adamala KP. Trumpet is an operating system for simple and robust cell-free biocomputing. Nature Communications. 14: 2257. PMID 37080970 DOI: 10.1038/s41467-023-37752-x  0.764
2023 Deich C, Gaut NJ, Sato W, Engelhart AE, Adamala KP. New Fluorescent Proteins for Cell-Free Bioengineering. Acs Synthetic Biology. PMID 37018763 DOI: 10.1021/acssynbio.3c00057  0.764
2023 Cash B, Gaut NJ, Deich C, Johnson LL, Engelhart AE, Adamala KP. Parasites, Infections, and Inoculation in Synthetic Minimal Cells. Acs Omega. 8: 7045-7056. PMID 36844541 DOI: 10.1021/acsomega.2c07911  0.749
2023 Deich C, Cash B, Sato W, Sharon J, Aufdembrink L, Gaut NJ, Heili J, Stokes K, Engelhart AE, Adamala KP. T7Max transcription system. Journal of Biological Engineering. 17: 4. PMID 36691081 DOI: 10.1186/s13036-023-00323-1  0.781
2022 Sato W, Rasmussen M, Deich C, Engelhart AE, Adamala KP. Expanding luciferase reporter systems for cell-free protein expression. Scientific Reports. 12: 11489. PMID 35798760 DOI: 10.1038/s41598-022-15624-6  0.766
2022 Sato W, Sharon J, Deich C, Gaut N, Cash B, Engelhart AE, Adamala KP. Akaby-Cell-free protein expression system for linear templates. Plos One. 17: e0266272. PMID 35390057 DOI: 10.1371/journal.pone.0266272  0.77
2022 Hoog TG, Pawlak MR, Aufdembrink LM, Bachan BR, Galles MB, Bense NB, Adamala KP, Engelhart AE. Switchable DNA-Based Peroxidases Controlled by a Chaotropic Ion. Chembiochem : a European Journal of Chemical Biology. e202200090. PMID 35245408 DOI: 10.1002/cbic.202200090  0.736
2022 Hoog TG, Pawlak MR, Bachan BF, Engelhart AE. DNA G-quadruplexes are uniquely stable in the presence of denaturants and monovalent cations. Biochemistry and Biophysics Reports. 30: 101238. PMID 35243016 DOI: 10.1016/j.bbrep.2022.101238  0.779
2022 Gaut NJ, Gomez-Garcia J, Heili JM, Cash B, Han Q, Engelhart AE, Adamala KP. Programmable Fusion and Differentiation of Synthetic Minimal Cells. Acs Synthetic Biology. PMID 35089706 DOI: 10.1021/acssynbio.1c00519  0.762
2020 Khan P, Aufdembrink LM, Engelhart AE. Isothermal SARS-CoV-2 Diagnostics: Tools for Enabling Distributed Pandemic Testing as a Means of Supporting Safe Reopenings. Acs Synthetic Biology. PMID 32966744 DOI: 10.1021/acssynbio.0c00359  0.754
2020 Hoog TG, Aufdembrink LM, Gaut NJ, Sung RJ, Adamala KP, Engelhart AE. Rapid deployment of smartphone-based augmented reality tools for field and online education in structural biology. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. PMID 32604463 DOI: 10.1002/Bmb.21396  0.717
2020 Aufdembrink LM, Khan P, Gaut NJ, Adamala KP, Engelhart AE. Highly specific, multiplexed isothermal pathogen detection with fluorescent aptamer readout. Rna (New York, N.Y.). PMID 32482894 DOI: 10.1261/Rna.075192.120  0.768
2019 Aufdembrink LM, Hoog TG, Pawlak MR, Bachan BF, Heili JM, Engelhart AE. Methods for thermal denaturation studies of nucleic acids in complex with fluorogenic dyes. Methods in Enzymology. 623: 23-43. PMID 31239049 DOI: 10.1016/Bs.Mie.2019.05.029  0.753
2018 Jin L, Engelhart AE, Zhang W, Adamala KP, Szostak JW. Catalysis of Template-directed Nonenzymatic RNA Copying by Iron (II). Journal of the American Chemical Society. PMID 30335371 DOI: 10.1021/Jacs.8B09617  0.786
2018 Jin L, Engelhart AE, Adamala KP, Szostak JW. Preparation, Purification, and Use of Fatty Acid-containing Liposomes. Journal of Visualized Experiments : Jove. PMID 29553563 DOI: 10.3791/57324  0.772
2018 Heili JM, Gomez-Garcia J, Gaut NJ, Cash BW, Aufdembrink LM, Heffron BA, Shirley JD, Carlson EE, Adamala KP, Engelhart AE. Real-Time Visualization of in Vitro Transcription of a Fluorescent RNA Aptamer: An Experiment for the Upper-Division Undergraduate or First-Year Graduate Laboratory Journal of Chemical Education. 95: 1867-1871. DOI: 10.1021/Acs.Jchemed.7B00735  0.765
2017 Engelhart AE. RNA imaging: A tale of two G-quadruplexes. Nature Chemical Biology. PMID 28945235 DOI: 10.1038/Nchembio.2492  0.386
2016 Engelhart AE, Adamala KP, Szostak JW. A simple physical mechanism enables homeostasis in primitive cells. Nature Chemistry. 8: 448-53. PMID 27102678 DOI: 10.1038/Nchem.2475  0.789
2016 Adamala KP, Engelhart AE, Szostak JW. Collaboration between primitive cell membranes and soluble catalysts. Nature Communications. 7: 11041. PMID 26996603 DOI: 10.1038/Ncomms11041  0.774
2015 Adamala K, Engelhart AE, Kamat NP, Jin L, Szostak JW. Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations. Nature Protocols. 10: 927-38. PMID 26020615 DOI: 10.1038/Nprot.2015.054  0.774
2015 Adamala K, Engelhart AE, Szostak JW. Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension. Journal of the American Chemical Society. 137: 483-9. PMID 25521912 DOI: 10.1021/Ja511564D  0.792
2015 Adamala K, Engelhart AE, Szostak JW. Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension Journal of the American Chemical Society. 137: 483-489. DOI: 10.1021/ja511564d  0.785
2014 Sheng J, Li L, Engelhart AE, Gan J, Wang J, Szostak JW. Structural insights into the effects of 2'-5' linkages on the RNA duplex. Proceedings of the National Academy of Sciences of the United States of America. 111: 3050-5. PMID 24516151 DOI: 10.1073/Pnas.1317799111  0.571
2014 Mamajanov I, Macdonald PJ, Ying J, Duncanson DM, Dowdy GR, Walker CA, Engelhart AE, Fernández FM, Grover MA, Hud NV, Schork FJ. Ester formation and hydrolysis during wet-dry cycles: Generation of far-from-equilibrium polymers in a model prebiotic reaction Macromolecules. 47: 1334-1343. DOI: 10.1021/Ma402256D  0.761
2013 Engelhart AE, Powner MW, Szostak JW. Functional RNAs exhibit tolerance for non-heritable 2'-5' versus 3'-5' backbone heterogeneity. Nature Chemistry. 5: 390-4. PMID 23609089 DOI: 10.1038/Nchem.1623  0.575
2013 Engelhart AE, Powner MW, Szostak JW. The ascent of molecules Nature Chemistry. 5: 349-349. PMID 23609072 DOI: 10.1038/Nchem.1647  0.472
2013 Engelhart AE, Powner MW, Szostak JW. 7 Imperfect RNA synthesis via model prebiotic reactions and consequences for functional RNAs Journal of Biomolecular Structure and Dynamics. 31: 4-5. DOI: 10.1080/07391102.2013.786333  0.567
2013 Sheng J, Li L, Engelhart AE, Szostak JW. 6 Crystal structure studies of RNA molecules containing 2′–5′-linkages Journal of Biomolecular Structure and Dynamics. 31: 4-4. DOI: 10.1080/07391102.2013.786332  0.532
2012 Engelhart AE, Cafferty BJ, Okafor CD, Chen MC, Williams LD, Lynn DG, Hud NV. Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR. Chembiochem : a European Journal of Chemical Biology. 13: 1121-4. PMID 22556064 DOI: 10.1002/Cbic.201200167  0.775
2010 Mamajanov I, Engelhart AE, Bean HD, Hud NV. DNA and RNA in anhydrous media: duplex, triplex, and G-quadruplex secondary structures in a deep eutectic solvent. Angewandte Chemie (International Ed. in English). 49: 6310-4. PMID 20623813 DOI: 10.1002/Anie.201001561  0.788
2010 Engelhart AE, Hud NV. Primitive genetic polymers. Cold Spring Harbor Perspectives in Biology. 2: a002196. PMID 20462999 DOI: 10.1101/Cshperspect.A002196  0.643
2010 Horowitz ED, Engelhart AE, Chen MC, Quarles KA, Smith MW, Lynn DG, Hud NV. Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world. Proceedings of the National Academy of Sciences of the United States of America. 107: 5288-93. PMID 20212163 DOI: 10.1073/Pnas.0914172107  0.794
2009 Engelhart AE, Morton TH, Hud NV. Evidence of strong hydrogen bonding by 8-aminoguanine. Chemical Communications (Cambridge, England). 647-9. PMID 19322409 DOI: 10.1039/B818409G  0.53
2009 Tsai AG, Engelhart AE, Hatmal MM, Houston SI, Hud NV, Haworth IS, Lieber MR. Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. The Journal of Biological Chemistry. 284: 7157-64. PMID 19106104 DOI: 10.1074/Jbc.M806866200  0.592
2008 Cetinkol OP, Engelhart AE, Nanjunda RK, Wilson WD, Hud NV. Submicromolar, selective G-quadruplex ligands from one pot: thermodynamic and structural studies of human telomeric DNA binding by azacyanines. Chembiochem : a European Journal of Chemical Biology. 9: 1889-92. PMID 18600816 DOI: 10.1002/Cbic.200800234  0.775
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