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Paul J. Lombroso, MD - Publications

Affiliations: 
Child Study Center and Departments of Neurobiology and Psychiatry Yale University, New Haven, CT 
Area:
molecular psychiatry
Website:
http://medicine.yale.edu/labs/lombroso/

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chatterjee M, Singh P, Xu J, Lombroso PJ, Kurup PK. Inhibition of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) Activity Reverses Behavioral Deficits in a Rodent Model of Autism. Behavioural Brain Research. 112713. PMID 32461127 DOI: 10.1016/j.bbr.2020.112713  0.41
2019 Mallozzi C, Pepponi R, Visentin S, Chiodi V, Lombroso PJ, Bader M, Popoli P, Domenici MR. The activity of the STriatal-Enriched protein tyrosine Phosphatase (STEP) in neuronal cells is modulated by adenosine A receptor. Journal of Neurochemistry. PMID 31520531 DOI: 10.1111/jnc.14866  0.39
2019 Dedek A, Xu J, Kandegedara CM, Lorenzo LÉ, Godin AG, De Koninck Y, Lombroso PJ, Tsai EC, Hildebrand ME. Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing. Brain : a Journal of Neurology. 142: 1535-1546. PMID 31135041 DOI: 10.1093/Brain/Awz105  0.332
2018 Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J. The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline. Current Biology : Cb. PMID 29576474 DOI: 10.1016/J.Cub.2018.02.047  0.513
2018 Bosco F, Valente P, Milanese M, Piccini A, Messa M, Bonanno G, Lombroso P, Baldelli P, Benfenati F, Giovedì S. Altered Intracellular Calcium Homeostasis Underlying Enhanced Glutamatergic Transmission in Striatal-Enriched Tyrosine Phosphatase (STEP) Knockout Mice. Molecular Neurobiology. PMID 29508281 DOI: 10.1007/S12035-018-0980-5  0.594
2017 Tjin CC, Otley KD, Baguley TD, Kurup P, Xu J, Nairn AC, Lombroso PJ, Ellman JA. Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases. Acs Central Science. 3: 1322-1328. PMID 29296673 DOI: 10.1021/Acscentsci.7B00486  0.534
2017 Witten MR, Wissler L, Snow M, Geschwindner S, Read JA, Brandon NJ, Nairn AC, Lombroso PJ, Käck H, Ellman JA. X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors. Journal of Medicinal Chemistry. PMID 29116812 DOI: 10.1021/Acs.Jmedchem.7B01292  0.537
2017 Chatterjee M, Kurup PK, Lundbye CJ, Hugger Toft AK, Kwon J, Benedict J, Kamceva M, Banke TG, Lombroso PJ. STEP inhibition reverses behavioral, electrophysiologic, and synaptic abnormalities in Fmr1 KO mice. Neuropharmacology. PMID 28943283 DOI: 10.1016/j.neuropharm.2017.09.026  0.411
2017 Xu J, Kurup P, Nairn AC, Lombroso PJ. Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP61. Molecular Neurobiology. PMID 28466270 DOI: 10.1007/s12035-017-0555-x  0.587
2017 Siemsen BM, Lombroso PJ, McGinty JF. Intra-prelimbic cortical inhibition of striatal-enriched tyrosine phosphatase suppresses cocaine seeking in rats. Addiction Biology. PMID 28349660 DOI: 10.1111/adb.12504  0.764
2016 Lombroso PJ, Ogren M, Kurup P, Nairn AC. Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity. F1000research. 5. PMID 29098072 DOI: 10.12688/f1000research.8571.1  0.588
2016 Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing. Cell Reports. 17: 2753-2765. PMID 27926876 DOI: 10.1016/J.Celrep.2016.11.024  0.359
2016 Tian M, Xu J, Lei G, Lombroso PJ, Jackson MF, MacDonald JF. STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit. Scientific Reports. 6: 36684. PMID 27857196 DOI: 10.1038/srep36684  0.387
2016 Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, ... ... Lombroso PJ, et al. Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models. Molecular Psychiatry. PMID 27752082 DOI: 10.1038/mp.2016.163  0.552
2016 Kamceva M, Benedict J, Nairn AC, Lombroso PJ. Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function. Neural Plasticity. 2016: 8136925. PMID 27190655 DOI: 10.1155/2016/8136925  0.59
2015 Xu J, Kurup P, Baguley TD, Foscue E, Ellman JA, Nairn AC, Lombroso PJ. Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice. Cellular and Molecular Life Sciences : Cmls. PMID 26450419 DOI: 10.1007/S00018-015-2057-1  0.55
2015 Jang SS, Royston SE, Xu J, Cavaretta JP, Vest MO, Lee KY, Lee S, Jeong HG, Lombroso PJ, Chung HJ. Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity. Molecular Brain. 8: 55. PMID 26391783 DOI: 10.1186/S13041-015-0148-4  0.799
2015 Xu J, Kurup P, Azkona G, Baguley TD, Saavedra A, Nairn AC, Ellman JA, Pérez-Navarro E, Lombroso PJ. Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels. Journal of Neurochemistry. PMID 26316048 DOI: 10.1111/Jnc.13295  0.581
2015 Azkona G, Saavedra A, Aira Z, Aluja D, Xifró X, Baguley T, Alberch J, Ellman JA, Lombroso PJ, Azkue JJ, Pérez-Navarro E. STEP modulates nociception: evidences from genetic deletion and pharmacological inhibition. Pain. PMID 26270590 DOI: 10.1097/J.Pain.0000000000000329  0.328
2015 Saavedra A, Puigdellívol M, Tyebji S, Kurup P, Xu J, Ginés S, Alberch J, Lombroso PJ, Pérez-Navarro E. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome. Molecular Neurobiology. PMID 26223799 DOI: 10.1007/S12035-015-9335-7  0.43
2015 Legastelois R, Darcq E, Wegner SA, Lombroso PJ, Ron D. Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking. Plos One. 10: e0127408. PMID 25992601 DOI: 10.1371/Journal.Pone.0127408  0.334
2015 Xu J, Kurup P, Foscue E, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway. Journal of Neurochemistry. 134: 629-41. PMID 25951993 DOI: 10.1111/jnc.13160  0.448
2015 Baguley TD, Nairn AC, Lombroso PJ, Ellman JA. Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP. Bioorganic & Medicinal Chemistry Letters. 25: 1044-6. PMID 25666825 DOI: 10.1016/J.Bmcl.2015.01.020  0.528
2015 Kurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ, Nairn AC. STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 112: 1202-7. PMID 25583483 DOI: 10.1073/pnas.1417423112  0.522
2014 Ng AN, Doherty AJ, Lombroso PJ, Emptage NJ, Collingridge GL. Rapid regulation of endoplasmic reticulum dynamics in dendritic spines by NMDA receptor activation. Molecular Brain. 7: 60. PMID 25242397 DOI: 10.1186/s13041-014-0060-3  0.35
2014 Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, ... ... Lombroso PJ, et al. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. Plos Biology. 12: e1001923. PMID 25093460 DOI: 10.1371/Journal.Pbio.1001923  0.651
2014 Gladding CM, Fan J, Zhang LY, Wang L, Xu J, Li EH, Lombroso PJ, Raymond LA. Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model. Journal of Neurochemistry. 130: 145-59. PMID 24588402 DOI: 10.1111/Jnc.12700  0.451
2013 Deb I, Manhas N, Poddar R, Rajagopal S, Allan AM, Lombroso PJ, Rosenberg GA, Candelario-Jalil E, Paul S. Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17814-26. PMID 24198371 DOI: 10.1523/Jneurosci.2346-12.2013  0.348
2013 Baguley TD, Xu HC, Chatterjee M, Nairn AC, Lombroso PJ, Ellman JA. Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase. Journal of Medicinal Chemistry. 56: 7636-50. PMID 24083656 DOI: 10.1021/Jm401037H  0.587
2013 Dabrowska J, Hazra R, Guo JD, Li C, Dewitt S, Xu J, Lombroso PJ, Rainnie DG. Striatal-enriched protein tyrosine phosphatase-STEPs toward understanding chronic stress-induced activation of corticotrophin releasing factor neurons in the rat bed nucleus of the stria terminalis. Biological Psychiatry. 74: 817-26. PMID 24012328 DOI: 10.1016/J.Biopsych.2013.07.032  0.403
2012 Johnson MA, Lombroso PJ. A common STEP in the synaptic pathology of diverse neuropsychiatric disorders. The Yale Journal of Biology and Medicine. 85: 481-90. PMID 23239949  0.336
2012 Olausson P, Venkitaramani DV, Moran TD, Salter MW, Taylor JR, Lombroso PJ. The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity. Neuroscience. 225: 1-8. PMID 22885232 DOI: 10.1016/j.neuroscience.2012.07.069  0.782
2012 Xu J, Kurup P, Nairn AC, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease. Advances in Pharmacology (San Diego, Calif.). 64: 303-25. PMID 22840751 DOI: 10.1016/B978-0-12-394816-8.00009-X  0.541
2012 Pelov I, Teltsh O, Greenbaum L, Rigbi A, Kanyas-Sarner K, Lerer B, Lombroso P, Kohn Y. Involvement of PTPN5, the gene encoding the striatal-enriched protein tyrosine phosphatase, in schizophrenia and cognition Psychiatric Genetics. 22: 168-176. PMID 22555153 DOI: 10.1097/YPG.0b013e3283518586  0.347
2012 Xu J, Kurup P, Bartos JA, Patriarchi T, Hell JW, Lombroso PJ. Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity. The Journal of Biological Chemistry. 287: 20942-56. PMID 22544749 DOI: 10.1074/Jbc.M112.368654  0.426
2012 Gladding CM, Sepers MD, Xu J, Zhang LY, Milnerwood AJ, Lombroso PJ, Raymond LA. Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model. Human Molecular Genetics. 21: 3739-52. PMID 22523092 DOI: 10.1093/hmg/dds154  0.46
2012 Goebel-Goody SM, Wilson-Wallis ED, Royston S, Tagliatela SM, Naegele JR, Lombroso PJ. Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model. Genes, Brain, and Behavior. 11: 586-600. PMID 22405502 DOI: 10.1111/J.1601-183X.2012.00781.X  0.782
2012 Braithwaite SP, Stock JB, Lombroso PJ, Nairn AC. Protein phosphatases and Alzheimer's disease. Progress in Molecular Biology and Translational Science. 106: 343-79. PMID 22340724 DOI: 10.1016/B978-0-12-396456-4.00012-2  0.536
2012 Goebel-Goody SM, Baum M, Paspalas CD, Fernandez SM, Carty NC, Kurup P, Lombroso PJ. Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders. Pharmacological Reviews. 64: 65-87. PMID 22090472 DOI: 10.1124/pr.110.003053  0.459
2012 Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, ... ... Lombroso PJ, et al. Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation. Acs Chemical Biology. 7: 367-77. PMID 22070201 DOI: 10.1021/Cb2004274  0.331
2011 Zhang Y, Kurup P, Xu J, Anderson GM, Greengard P, Nairn AC, Lombroso PJ. Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization. Journal of Neurochemistry. 119: 664-72. PMID 21883219 DOI: 10.1111/j.1471-4159.2011.07450.x  0.639
2011 Moura PJ, Venkitaramani DV, Tashev R, Lombroso PJ, Xavier GF. Transport of animals between rooms: a little-noted aspect of laboratory procedure that may interfere with memory. Behavioural Processes. 88: 12-9. PMID 21729741 DOI: 10.1016/j.beproc.2011.06.008  0.722
2011 Saavedra A, Giralt A, Rué L, Xifró X, Xu J, Ortega Z, Lucas JJ, Lombroso PJ, Alberch J, Pérez-Navarro E. Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8150-62. PMID 21632937 DOI: 10.1523/Jneurosci.3446-10.2011  0.435
2011 Venkitaramani DV, Moura PJ, Picciotto MR, Lombroso PJ. Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory. The European Journal of Neuroscience. 33: 2288-98. PMID 21501258 DOI: 10.1111/j.1460-9568.2011.07687.x  0.807
2011 Hicklin TR, Wu PH, Radcliffe RA, Freund RK, Goebel-Goody SM, Correa PR, Proctor WR, Lombroso PJ, Browning MD. Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 108: 6650-5. PMID 21464302 DOI: 10.1073/Pnas.1017856108  0.528
2011 Briggs SW, Walker J, Asik K, Lombroso P, Naegele J, Aaron G. STEP regulation of seizure thresholds in the hippocampus. Epilepsia. 52: 497-506. PMID 21204826 DOI: 10.1111/J.1528-1167.2010.02912.X  0.617
2010 Baum ML, Kurup P, Xu J, Lombroso PJ. A STEP forward in neural function and degeneration. Communicative & Integrative Biology. 3: 419-22. PMID 21057629 DOI: 10.4161/cib.3.5.12692  0.469
2010 Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC, Lombroso PJ. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 107: 19014-9. PMID 20956308 DOI: 10.1073/pnas.1013543107  0.632
2010 Kurup P, Zhang Y, Venkitaramani DV, Xu J, Lombroso PJ. The role of STEP in Alzheimer's disease. Channels (Austin, Tex.). 4: 347-50. PMID 20699650 DOI: 10.1523/Jneurosci.0157-10.2010  0.776
2010 Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P, Nairn AC, Lombroso PJ. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5948-57. PMID 20427654 DOI: 10.1523/JNEUROSCI.0157-10.2010  0.799
2010 Kurup P, Zhang Y, Venkitaramani DV, Xu J, Lombroso PJ. The role of STEP in Alzheimer disease Channels. 4.  0.708
2009 Xu J, Kurup P, Zhang Y, Goebel-Goody SM, Wu PH, Hawasli AH, Baum ML, Bibb JA, Lombroso PJ. Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9330-43. PMID 19625523 DOI: 10.1523/Jneurosci.2212-09.2009  0.678
2009 Chen J, Rusnak M, Lombroso PJ, Sidhu A. Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. The European Journal of Neuroscience. 29: 287-306. PMID 19200235 DOI: 10.1111/J.1460-9568.2008.06590.X  0.384
2009 Paspalas CD, Perley CC, Venkitaramani DV, Goebel-Goody SM, Zhang Y, Kurup P, Mattis JH, Lombroso PJ. Major vault protein is expressed along the nucleus-neurite axis and associates with mRNAs in cortical neurons. Cerebral Cortex (New York, N.Y. : 1991). 19: 1666-77. PMID 19029061 DOI: 10.1093/cercor/bhn203  0.752
2009 Tashev R, Moura PJ, Venkitaramani DV, Prosperetti C, Centonze D, Paul S, Lombroso PJ. A substrate trapping mutant form of striatal-enriched protein tyrosine phosphatase prevents amphetamine-induced stereotypies and long-term potentiation in the striatum. Biological Psychiatry. 65: 637-45. PMID 19026408 DOI: 10.1016/J.Biopsych.2008.10.008  0.722
2009 Venkitaramani DV, Paul S, Zhang Y, Kurup P, Ding L, Tressler L, Allen M, Sacca R, Picciotto MR, Lombroso PJ. Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation. Synapse (New York, N.Y.). 63: 69-81. PMID 18932218 DOI: 10.1002/syn.20608  0.8
2008 Lombroso PJ, Ogren MP. Learning and memory, part I: brain regions involved in two types of learning and memory. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 1228-32. PMID 18931610 DOI: 10.1097/CHI.0b013e318186e638  0.336
2008 Zhang Y, Venkitaramani DV, Gladding CM, Zhang Y, Kurup P, Molnar E, Collingridge GL, Lombroso PJ. The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10561-6. PMID 18923032 DOI: 10.1523/Jneurosci.2666-08.2008  0.789
2008 Ogren MP, Lombroso PJ. Reversing the effects of fragile X syndrome. Journal of the American Academy of Child and Adolescent Psychiatry. 47: 863-7. PMID 18645420 DOI: 10.1097/CHI.0b0 13e318179a057  0.306
2008 Braithwaite SP, Xu J, Leung J, Urfer R, Nikolich K, Oksenberg D, Lombroso PJ, Shamloo M. Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. The European Journal of Neuroscience. 27: 2444-52. PMID 18445231 DOI: 10.1111/J.1460-9568.2008.06209.X  0.387
2008 Wu PH, Freund RK, Procotor WR, Goebel-Goody SM, Browning MD, Lombroso PJ. STriatal Enriched Protein Tyrosine Phosphatase mediates Ethanol inhibition of NMDA Receptor Activity Nature Precedings. DOI: 10.1038/Npre.2008.2473.1  0.379
2007 Venkitaramani DV, Chin J, Netzer WJ, Gouras GK, Lesne S, Malinow R, Lombroso PJ. Beta-amyloid modulation of synaptic transmission and plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11832-7. PMID 17978019 DOI: 10.1523/Jneurosci.3478-07.2007  0.731
2007 Hu Y, Zhang Y, Venkitaramani DV, Lombroso PJ. Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation. Journal of Neurochemistry. 103: 531-41. PMID 17623046 DOI: 10.1111/j.1471-4159.2007.04749.x  0.774
2007 Venkitaramani DV, Lombroso PJ. Molecular basis of genetic neuropsychiatric disorders. Child and Adolescent Psychiatric Clinics of North America. 16: 541-56. PMID 17562578 DOI: 10.1016/j.chc.2007.03.003  0.722
2007 Choi YS, Lin SL, Lee B, Kurup P, Cho HY, Naegele JR, Lombroso PJ, Obrietan K. Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2999-3009. PMID 17360923 DOI: 10.1523/Jneurosci.4913-06.2007  0.663
2007 Paul S, Olausson P, Venkitaramani DV, Ruchkina I, Moran TD, Tronson N, Mills E, Hakim S, Salter MW, Taylor JR, Lombroso PJ. The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala. Biological Psychiatry. 61: 1049-61. PMID 17081505 DOI: 10.1016/j.biopsych.2006.08.005  0.768
2006 Kansy JW, Katsovich L, McIver KS, Pick J, Zabriskie JB, Lombroso PJ, Leckman JF, Bibb JA. Identification of pyruvate kinase as an antigen associated with Tourette syndrome. Journal of Neuroimmunology. 181: 165-76. PMID 17011640 DOI: 10.1016/j.jneuroim.2006.08.007  0.601
2006 Braithwaite SP, Paul S, Nairn AC, Lombroso PJ. Synaptic plasticity: one STEP at a time. Trends in Neurosciences. 29: 452-8. PMID 16806510 DOI: 10.1016/j.tins.2006.06.007  0.588
2005 Snyder EM, Nong Y, Almeida CG, Paul S, Moran T, Choi EY, Nairn AC, Salter MW, Lombroso PJ, Gouras GK, Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nature Neuroscience. 8: 1051-8. PMID 16025111 DOI: 10.1038/Nn1503  0.706
2005 Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P, Hervé D, Girault JA. Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proceedings of the National Academy of Sciences of the United States of America. 102: 491-6. PMID 15608059 DOI: 10.1073/Pnas.0408305102  0.74
2004 Nika K, Hyunh H, Williams S, Paul S, Bottini N, Taskén K, Lombroso PJ, Mustelin T. Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location. The Biochemical Journal. 378: 335-42. PMID 14613483 DOI: 10.1042/Bj20031244  0.353
2003 Blitzer R, Lombroso PJ. Genetics of childhood disorders: LIII. Learning and memory, part 6: induction of long-term potentiation. Journal of the American Academy of Child and Adolescent Psychiatry. 42: 998-1001. PMID 12874504 DOI: 10.1097/01.CHI.0000046894.27264.9D  0.331
2003 Paul S, Nairn AC, Wang P, Lombroso PJ. NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nature Neuroscience. 6: 34-42. PMID 12483215 DOI: 10.1038/nn989  0.565
2002 Nguyen TH, Liu J, Lombroso PJ. Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420. The Journal of Biological Chemistry. 277: 24274-9. PMID 11983687 DOI: 10.1074/Jbc.M111683200  0.362
2002 Pelkey KA, Askalan R, Paul S, Kalia LV, Nguyen TH, Pitcher GM, Salter MW, Lombroso PJ. Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation. Neuron. 34: 127-38. PMID 11931747 DOI: 10.1016/S0896-6273(02)00633-5  0.395
2001 Naegele JR, Lombroso PJ. Genetics of central nervous system developmental disorders. Child and Adolescent Psychiatric Clinics of North America. 10: 225-39. PMID 11351796 DOI: 10.1016/S1056-4993(18)30055-5  0.585
2000 Paul S, Snyder GL, Yokakura H, Picciotto MR, Nairn AC, Lombroso PJ. The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5630-8. PMID 10908600 DOI: 10.1523/Jneurosci.20-15-05630.2000  0.68
1998 Hockfield S, Lombroso PJ. Development of the cerebral cortex: IX. Cortical development and experience: I. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 992-3. PMID 9735620 DOI: 10.1097/00004583-199809000-00021  0.334
1998 Naegele J, Lombroso PJ. Development of the cerebral cortex: VIII. Apoptosis: neuronal Hari-Kari. Journal of the American Academy of Child and Adolescent Psychiatry. 37: 890-2. PMID 9695453 DOI: 10.1097/00004583-199808000-00021  0.59
1996 Bult A, Zhao F, Dirkx R, Sharma E, Lukacsi E, Solimena M, Naegele JR, Lombroso PJ. STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7821-31. PMID 8987810 DOI: 10.1523/Jneurosci.16-24-07821.1996  0.636
1996 Raghunathan A, Matthews GA, Lombroso PJ, Naegele JR. Transient compartmental expression of a family of protein tyrosine phosphatases in the developing striatum. Brain Research. Developmental Brain Research. 91: 190-9. PMID 8852369 DOI: 10.1016/0165-3806(95)00176-X  0.641
1995 Boulanger LM, Lombroso PJ, Raghunathan A, During MJ, Wahle P, Naegele JR. Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1532-44. PMID 7869116 DOI: 10.1523/Jneurosci.15-02-01532.1995  0.62
1994 Naegele JR, Lombroso PJ. Protein tyrosine phosphatases in the nervous system. Critical Reviews in Neurobiology. 9: 105-14. PMID 8828006  0.623
1993 Lombroso PJ, Naegele JR, Sharma E, Lerner M. A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3064-74. PMID 8331384 DOI: 10.1523/Jneurosci.13-07-03064.1993  0.647
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