Thomas S. Kilduff - Publications

Affiliations: 
SRI International, Menlo Park, CA, United States 
Area:
sleep, circadian rhythms, hibernation, hypocretin, orexin

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Goonawardena AV, Morairty SR, Orellana GA, Willoughby AR, Wallace TL, Kilduff TS. Electrophysiological characterization of sleep/wake, activity and the response to caffeine in adult cynomolgus macaques. Neurobiology of Sleep and Circadian Rhythms. 6: 9-23. PMID 31236518 DOI: 10.1016/j.nbscr.2018.08.001  1
2019 Goonawardena AV, Morairty SR, Dell R, Orellana GA, Hoener MC, Wallace TL, Kilduff TS. Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30954024 DOI: 10.1038/s41386-019-0386-8  1
2018 Heiss JE, Yamanaka A, Kilduff TS. Parallel Arousal Pathways in the Lateral Hypothalamus. Eneuro. 5. PMID 30225361 DOI: 10.1523/ENEURO.0228-18.2018  0.84
2018 Williams RH, Black SW, Thomas AM, Piquet J, Cauli B, Kilduff TS. Excitation of Cortical nNOS/NK1R Neurons by Hypocretin 1 is Independent of Sleep Homeostasis. Cerebral Cortex (New York, N.Y. : 1991). PMID 29462275 DOI: 10.1093/cercor/bhy015  1
2018 Schwartz MD, Palmerston JB, Lee DL, Hoener MC, Kilduff TS. Deletion of Trace Amine-Associated Receptor 1 Attenuates Behavioral Responses to Caffeine. Frontiers in Pharmacology. 9: 35. PMID 29456505 DOI: 10.3389/fphar.2018.00035  0.88
2017 Thomas AM, Schwartz MD, Saxe MD, Kilduff TS. Sleep/wake physiology and quantitative EEG analysis of the Neuroligin-3 knockout rat model of autism spectrum disorder. Sleep. PMID 28958035 DOI: 10.1093/sleep/zsx138  0.88
2017 Gerashchenko D, Pasumarthi RK, Kilduff TS. Plasticity-Related Gene Expression During Eszopiclone-Induced Sleep. Sleep. PMID 28605546 DOI: 10.1093/sleep/zsx098  1
2017 Williams RH, Vazquez-DeRose J, Thomas AM, Piquet J, Cauli B, Kilduff TS. Cortical nNOS/NK1 Receptor Neurons are Regulated by Cholinergic Projections From the Basal Forebrain. Cerebral Cortex (New York, N.Y. : 1991). 1-21. PMID 28472227 DOI: 10.1093/cercor/bhx102  0.84
2017 Thomas AM, Schwartz MD, Saxe MD, Kilduff TS. Cntnap2 Knockout Rats and Mice Exhibit Epileptiform Activity and Abnormal Sleep-Wake Physiology. Sleep. 40. PMID 28364455 DOI: 10.1093/sleep/zsw026  0.88
2017 Peyron C, Kilduff TS. Mapping the Hypocretin/Orexin Neuronal System: An Unexpectedly Productive Journey. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 2268-2272. PMID 28250055 DOI: 10.1523/JNEUROSCI.1708-16.2016  1
2016 Black SW, Schwartz MD, Chen TM, Hoener MC, Kilduff TS. Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics. Biological Psychiatry. PMID 27919403 DOI: 10.1016/j.biopsych.2016.10.012  1
2016 Thomas AM, Schwartz MD, Saxe MD, Kilduff TS. Cntnap2 knockout rats and mice exhibit epileptiform activity and abnormal sleep/wake physiology. Sleep. PMID 27692059  0.88
2016 Schwartz MD, Black SW, Fisher SP, Palmerston JB, Morairty SR, Hoener MC, Kilduff TS. Trace Amine-Associated Receptor 1 Regulates Wakefulness and Eeg Spectral Composition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27658486 DOI: 10.1038/npp.2016.216  1
2016 Schwartz MD, Nguyen AT, Warrier DR, Palmerston JB, Thomas AM, Morairty SR, Neylan TC, Kilduff TS. Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep. Eneuro. 3. PMID 27022631 DOI: 10.1523/ENEURO.0018-16.2016  1
2016 Black SW, Kilduff TS. H1N1 infection of sleep/wake regions results in narcolepsy-like symptoms. Proceedings of the National Academy of Sciences of the United States of America. PMID 26747601 DOI: 10.1073/pnas.1524150113  1
2016 Fisher SP, Schwartz MD, Wurts-Black S, Thomas AM, Chen TM, Miller MA, Palmerston JB, Kilduff TS, Morairty SR. Quantitative electroencephalographic analysis provides an early-stage indicator of disease onset and progression in the zQ175 knock-in mouse model of huntington's disease Sleep. 39: 379-391. DOI: 10.5665/sleep.5448  1
2015 Black SW, Yamanaka A, Kilduff TS. CHALLENGES IN THE DEVELOPMENT OF THERAPEUTICS FOR NARCOLEPSY. Progress in Neurobiology. PMID 26721620 DOI: 10.1016/j.pneurobio.2015.12.002  1
2015 Schwartz MD, Kilduff TS. The Neurobiology of Sleep and Wakefulness. The Psychiatric Clinics of North America. 38: 615-44. PMID 26600100 DOI: 10.1016/j.psc.2015.07.002  1
2015 Fisher SP, Schwartz MD, Wurts-Black S, Thomas AM, Chen TM, Miller MA, Palmerston JB, Kilduff TS, Morairty SR. Quantitative Electroencephalographic Analysis Provides an Early-Stage Indicator of Disease Onset and Progression in the zQ175 Knock-In Mouse Model of Huntington Disease. Sleep. PMID 26446107  1
2015 Parks GS, Warrier DR, Dittrich L, Schwartz MD, Palmerston JB, Neylan TC, Morairty SR, Kilduff TS. The Dual Hypocretin Receptor Antagonist Almorexant is Permissive for Activation of Wake-Promoting Systems. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26289145 DOI: 10.1038/npp.2015.256  1
2015 Lindemann L, Porter RH, Scharf SH, Kuennecke B, Bruns A, von Kienlin M, Harrison AC, Paehler A, Funk C, Gloge A, Schneider M, Parrott NJ, Polonchuk L, Niederhauser U, Morairty SR, ... Kilduff TS, et al. Pharmacology of basimglurant (RO4917523, RG7090), a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depression. The Journal of Pharmacology and Experimental Therapeutics. 353: 213-33. PMID 25665805 DOI: 10.1124/jpet.114.222463  1
2015 Dittrich L, Morairty SR, Warrier DR, Kilduff TS. Homeostatic sleep pressure is the primary factor for activation of cortical nNOS/NK1 neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 632-9. PMID 25139062 DOI: 10.1038/npp.2014.212  1
2014 Vazquez-DeRose J, Schwartz MD, Nguyen AT, Warrier DR, Gulati S, Mathew TK, Neylan TC, Kilduff TS. Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. Brain Structure & Function. PMID 25431268 DOI: 10.1007/s00429-014-0946-y  1
2014 Tsunematsu T, Ueno T, Tabuchi S, Inutsuka A, Tanaka KF, Hasuwa H, Kilduff TS, Terao A, Yamanaka A. Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6896-909. PMID 24828644 DOI: 10.1523/JNEUROSCI.5344-13.2014  1
2014 Tabuchi S, Tsunematsu T, Black SW, Tominaga M, Maruyama M, Takagi K, Minokoshi Y, Sakurai T, Kilduff TS, Yamanaka A. Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6495-509. PMID 24806676 DOI: 10.1523/JNEUROSCI.0073-14.2014  1
2014 Black SW, Morairty SR, Chen TM, Leung AK, Wisor JP, Yamanaka A, Kilduff TS. GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6485-94. PMID 24806675 DOI: 10.1523/JNEUROSCI.0080-14.2014  1
2014 Morairty SR, Wilk AJ, Lincoln WU, Neylan TC, Kilduff TS. The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats. Frontiers in Neuroscience. 8: 3. PMID 24550767 DOI: 10.3389/fnins.2014.00003  1
2013 Morairty SR, Dittrich L, Pasumarthi RK, Valladao D, Heiss JE, Gerashchenko D, Kilduff TS. A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 20272-7. PMID 24191004 DOI: 10.1073/pnas.1314762110  1
2013 Krystal AD, Benca RM, Kilduff TS. Understanding the sleep-wake cycle: sleep, insomnia, and the orexin system. The Journal of Clinical Psychiatry. 74: 3-20. PMID 24107804 DOI: 10.4088/JCP.13011su1c  1
2013 Tabuchi S, Tsunematsu T, Kilduff TS, Sugio S, Xu M, Tanaka KF, Takahashi S, Tominaga M, Yamanaka A. Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness. Sleep. 36: 1391-404. PMID 23997373 DOI: 10.5665/sleep.2972  1
2013 Bittman EL, Kilduff TS, Kriegsfeld LJ, Szymusiak R, Toth LA, Turek FW. Animal care practices in experiments on biological rhythms and sleep: report of the Joint Task Force of the Society for Research on Biological Rhythms and the Sleep Research Society. Journal of the American Association For Laboratory Animal Science : Jaalas. 52: 437-43. PMID 23849440  1
2013 Fisher SP, Black SW, Schwartz MD, Wilk AJ, Chen TM, Lincoln WU, Liu HW, Kilduff TS, Morairty SR. Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6/2 mouse model of Huntington's disease. Brain : a Journal of Neurology. 136: 2159-72. PMID 23801738 DOI: 10.1093/brain/awt132  1
2013 Black SW, Morairty SR, Fisher SP, Chen TM, Warrier DR, Kilduff TS. Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy. Sleep. 36: 325-36. PMID 23449602 DOI: 10.5665/sleep.2442  1
2013 Revel FG, Moreau JL, Pouzet B, Mory R, Bradaia A, Buchy D, Metzler V, Chaboz S, Groebke Zbinden K, Galley G, Norcross RD, Tuerck D, Bruns A, Morairty SR, Kilduff TS, et al. A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight. Molecular Psychiatry. 18: 543-56. PMID 22641180 DOI: 10.1038/mp.2012.57  1
2012 Morairty SR, Revel FG, Malherbe P, Moreau JL, Valladao D, Wettstein JG, Kilduff TS, Borroni E. Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone. Plos One. 7: e39131. PMID 22768296 DOI: 10.1371/journal.pone.0039131  1
2012 Revel FG, Moreau JL, Gainetdinov RR, Ferragud A, Velázquez-Sánchez C, Sotnikova TD, Morairty SR, Harmeier A, Groebke Zbinden K, Norcross RD, Bradaia A, Kilduff TS, Biemans B, Pouzet B, Caron MG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biological Psychiatry. 72: 934-42. PMID 22705041 DOI: 10.1016/j.biopsych.2012.05.014  1
2012 Dittrich L, Heiss JE, Warrier DR, Perez XA, Quik M, Kilduff TS. Cortical nNOS neurons co-express the NK1 receptor and are depolarized by Substance P in multiple mammalian species. Frontiers in Neural Circuits. 6: 31. PMID 22679419 DOI: 10.3389/fncir.2012.00031  1
2012 Pasumarthi RK, Kilduff TS. Novel pathways for stimulant development II: The hypocretin/orexin system Sleep Deprivation, Stimulant Medications, and Cognition. 165-183. DOI: 10.1017/CBO9780511783005.014  1
2011 Wisor JP, Gerashchenko D, Kilduff TS. Sleep-active neuronal nitric oxide synthase-positive cells of the cerebral cortex: a local regulator of sleep? Current Topics in Medicinal Chemistry. 11: 2483-9. PMID 21906016  1
2011 Tsunematsu T, Kilduff TS, Boyden ES, Takahashi S, Tominaga M, Yamanaka A. Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10529-39. PMID 21775598 DOI: 10.1523/JNEUROSCI.0784-11.2011  1
2011 Gerashchenko D, Wisor JP, Kilduff TS. Sleep-active cells in the cerebral cortex and their role in slow-wave activity. Sleep and Biological Rhythms. 9: 71-77. PMID 21625335 DOI: 10.1111/j.1479-8425.2010.00461.x  1
2011 Hirashima N, Tsunematsu T, Ichiki K, Tanaka H, Kilduff TS, Yamanaka A. Neuropeptide B induces slow wave sleep in mice. Sleep. 34: 31-7. PMID 21203369  1
2011 Kilduff TS, Cauli B, Gerashchenko D. Activation of cortical interneurons during sleep: an anatomical link to homeostatic sleep regulation? Trends in Neurosciences. 34: 10-9. PMID 21030095 DOI: 10.1016/j.tins.2010.09.005  1
2011 Morairty SR, Wisor J, Silveira K, Sinko W, Kilduff TS. The wake-promoting effects of hypocretin-1 are attenuated in old rats. Neurobiology of Aging. 32: 1514-27. PMID 19781813 DOI: 10.1016/j.neurobiolaging.2009.07.017  1
2010 Thompson CL, Wisor JP, Lee CK, Pathak SD, Gerashchenko D, Smith KA, Fischer SR, Kuan CL, Sunkin SM, Ng LL, Lau C, Hawrylycz M, Jones AR, Kilduff TS, Lein ES. Molecular and anatomical signatures of sleep deprivation in the mouse brain. Frontiers in Neuroscience. 4: 165. PMID 21088695 DOI: 10.3389/fnins.2010.00165  1
2010 Pasumarthi RK, Gerashchenko D, Kilduff TS. Further characterization of sleep-active neuronal nitric oxide synthase neurons in the mouse brain. Neuroscience. 169: 149-57. PMID 20438808 DOI: 10.1016/j.neuroscience.2010.04.066  1
2010 Teegarden BR, Li H, Jayakumar H, Strah-Pleynet S, Dosa PI, Selaya SD, Kato N, Elwell KH, Davidson J, Cheng K, Saldana H, Frazer JM, Whelan K, Foster J, Espitia S, ... ... Kilduff TS, et al. Discovery of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (nelotanserin) and related 5-hydroxytryptamine2A inverse agonists for the treatment of insomnia. Journal of Medicinal Chemistry. 53: 1923-36. PMID 20143782 DOI: 10.1021/jm9007328  1
2010 Kilduff TS. Hibernation Encyclopedia of Neuroscience. 1113-1117. DOI: 10.1016/B978-008045046-9.01769-1  1
2009 Hara J, Gerashchenko D, Wisor JP, Sakurai T, Xie X, Kilduff TS. Thyrotropin-releasing hormone increases behavioral arousal through modulation of hypocretin/orexin neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3705-14. PMID 19321767 DOI: 10.1523/JNEUROSCI.0431-09.2009  1
2009 Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami K, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture. Proceedings of the National Academy of Sciences of the United States of America. 106: 4459-64. PMID 19246384 DOI: 10.1073/pnas.0811126106  1
2009 Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami KI, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 11, (4459-4464) DOI: 10.1073/pnas.0811126106) Proceedings of the National Academy of Sciences of the United States of America. 106: 8790. DOI: 10.1073/pnas.0903224106  1
2008 Kilduff TS, Lein ES, de la Iglesia H, Sakurai T, Fu YH, Shaw P. New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11814-8. PMID 19005045 DOI: 10.1523/JNEUROSCI.3768-08.2008  1
2008 Gerashchenko D, Wisor JP, Burns D, Reh RK, Shiromani PJ, Sakurai T, de la Iglesia HO, Kilduff TS. Identification of a population of sleep-active cerebral cortex neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 10227-32. PMID 18645184 DOI: 10.1073/pnas.0803125105  1
2008 Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7193-201. PMID 18614689 DOI: 10.1523/JNEUROSCI.1150-08.2008  1
2008 Xie X, Wisor JP, Hara J, Crowder TL, LeWinter R, Khroyan TV, Yamanaka A, Diano S, Horvath TL, Sakurai T, Toll L, Kilduff TS. Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. The Journal of Clinical Investigation. 118: 2471-81. PMID 18551194 DOI: 10.1172/JCI35115  1
2008 Terao A, Huang ZL, Wisor JP, Mochizuki T, Gerashchenko D, Urade Y, Kilduff TS. Gene expression in the rat brain during prostaglandin D2 and adenosinergically-induced sleep. Journal of Neurochemistry. 105: 1480-98. PMID 18331290 DOI: 10.1111/j.1471-4159.2008.05257.x  1
2008 Morairty SR, Hedley L, Flores J, Martin R, Kilduff TS. Selective 5HT2A and 5HT6 receptor antagonists promote sleep in rats. Sleep. 31: 34-44. PMID 18220076  1
2008 Doran SM, Wessel T, Kilduff TS, Turek F, Renger JJ. Translational models of sleep and sleep disorders Animal and Translational Models For Cns Drug Discovery. 1: 395-456. DOI: 10.1016/B978-0-12-373861-5.00012-6  1
2008 Wisor JP, Pasumarthi RK, Gerashchenko D, Thompson CL, Pathak S, Sancar A, Franken P, Lein ES, Kilduff TS. Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains (Journal of Neuroscience (July 9, 2008) (7193-7201)) Journal of Neuroscience. 28: 7929.  1
2006 Wisor JP, Morairty SR, Huynh NT, Steininger TL, Kilduff TS. Gene expression in the rat cerebral cortex: comparison of recovery sleep and hypnotic-induced sleep. Neuroscience. 141: 371-8. PMID 16690212 DOI: 10.1016/j.neuroscience.2006.03.028  1
2006 Xie X, Crowder TL, Yamanaka A, Morairty SR, Lewinter RD, Sakurai T, Kilduff TS. GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus. The Journal of Physiology. 574: 399-414. PMID 16627567 DOI: 10.1113/jphysiol.2006.108266  1
2006 Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T. Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner. Journal of Neurophysiology. 96: 284-98. PMID 16611835 DOI: 10.1152/jn.01361.2005  1
2006 Terao A, Wisor JP, Peyron C, Apte-Deshpande A, Wurts SW, Edgar DM, Kilduff TS. Gene expression in the rat brain during sleep deprivation and recovery sleep: an Affymetrix GeneChip study. Neuroscience. 137: 593-605. PMID 16257491 DOI: 10.1016/j.neuroscience.2005.08.059  1
2005 Wisor JP, Kilduff TS. Molecular genetic advances in sleep research and their relevance to sleep medicine. Sleep. 28: 357-67. PMID 16173658  1
2005 Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T. Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7459-69. PMID 16093397 DOI: 10.1523/JNEUROSCI.1193-05.2005  1
2005 Kilduff TS. Hypocretin/orexin: maintenance of wakefulness and a multiplicity of other roles. Sleep Medicine Reviews. 9: 227-30. PMID 15998593 DOI: 10.1016/j.smrv.2005.04.002  1
2005 Terao A, Kilduff TS. Sleep and aging: molecular approaches within a systems neurobiology context Advances in Cell Aging and Gerontology. 17: 165-191. DOI: 10.1016/S1566-3124(04)17007-7  1
2005 Steininger TL, Kilduff TS. Anatomy of the hypocretin system Hypocretins: Integrators of Physiological Functions. 61-75. DOI: 10.1007/0-387-25446-3_5  1
2004 Winsky-Sommerer R, Yamanaka A, Diano S, Borok E, Roberts AJ, Sakurai T, Kilduff TS, Horvath TL, de Lecea L. Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11439-48. PMID 15601950 DOI: 10.1523/JNEUROSCI.3459-04.2004  1
2004 Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7159-66. PMID 15306649 DOI: 10.1523/JNEUROSCI.1027-04.2004  1
2004 Steininger TL, Kilduff TS, Behan M, Benca RM, Landry CF. Comparison of hypocretin/orexin and melanin-concentrating hormone neurons and axonal projections in the embryonic and postnatal rat brain. Journal of Chemical Neuroanatomy. 27: 165-81. PMID 15183202 DOI: 10.1016/j.jchemneu.2004.02.007  1
2004 Terao A, Steininger TL, Morairty SR, Kilduff TS. Age-related changes in histamine receptor mRNA levels in the mouse brain. Neuroscience Letters. 355: 81-4. PMID 14729240 DOI: 10.1016/j.neulet.2003.10.061  1
2004 Kilduff TS, Steininger TL, Terao A. cDNA array studies of natural and pharmacologically induced sleep Sleep and Biological Rhythms. 2: S31-S33. DOI: 10.1111/j.1479-8425.2004.00099.x  1
2003 Terao A, Greco MA, Davis RW, Heller HC, Kilduff TS. Region-specific changes in immediate early gene expression in response to sleep deprivation and recovery sleep in the mouse brain. Neuroscience. 120: 1115-24. PMID 12927216 DOI: 10.1016/S0306-4522(03)00395-6  1
2003 Mistlberger RE, Antle MC, Kilduff TS, Jones M. Food- and light-entrained circadian rhythms in rats with hypocretin-2-saporin ablations of the lateral hypothalamus. Brain Research. 980: 161-8. PMID 12867254 DOI: 10.1016/S0006-8993(03)02755-0  1
2003 Terao A, Steininger TL, Hyder K, Apte-Deshpande A, Ding J, Rishipathak D, Davis RW, Heller HC, Kilduff TS. Differential increase in the expression of heat shock protein family members during sleep deprivation and during sleep. Neuroscience. 116: 187-200. PMID 12535952 DOI: 10.1016/S0306-4522(02)00695-4  1
2002 Wisor JP, O'Hara BF, Terao A, Selby CP, Kilduff TS, Sancar A, Edgar DM, Franken P. A role for cryptochromes in sleep regulation. Bmc Neuroscience. 3: 20. PMID 12495442 DOI: 10.1186/1471-2202-3-20  1
2002 Terao A, Apte-Deshpande A, Dousman L, Morairty S, Eynon BP, Kilduff TS, Freund YR. Immune response gene expression increases in the aging murine hippocampus. Journal of Neuroimmunology. 132: 99-112. PMID 12417439 DOI: 10.1016/S0165-5728(02)00317-X  1
2002 Terao A, Apte-Deshpande A, Morairty S, Freund YR, Kilduff TS. Age-related decline in hypocretin (orexin) receptor 2 messenger RNA levels in the mouse brain. Neuroscience Letters. 332: 190-4. PMID 12399012 DOI: 10.1016/S0304-3940(02)00953-9  1
2002 Waleh NS, Cravatt BF, Apte-Deshpande A, Terao A, Kilduff TS. Transcriptional regulation of the mouse fatty acid amide hydrolase gene. Gene. 291: 203-10. PMID 12095693 DOI: 10.1016/S0378-1119(02)00598-X  1
2001 Mikkelsen JD, Hauser F, deLecea L, Sutcliffe JG, Kilduff TS, Calgari C, Pévet P, Simonneaux V. Hypocretin (orexin) in the rat pineal gland: a central transmitter with effects on noradrenaline-induced release of melatonin. The European Journal of Neuroscience. 14: 419-25. PMID 11553292 DOI: 10.1046/j.0953-816X.2001.01655.x  1
2001 Gerashchenko D, Kohls MD, Greco M, Waleh NS, Salin-Pascual R, Kilduff TS, Lappi DA, Shiromani PJ. Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7273-83. PMID 11549737  1
2001 Kilduff TS, de Lecea L. Mapping of the mRNAs for the hypocretin/orexin and melanin-concentrating hormone receptors: networks of overlapping peptide systems. The Journal of Comparative Neurology. 435: 1-5. PMID 11370007 DOI: 10.1002/cne.1189  1
2001 Kilduff TS. Sleepy dogs don't lie: a genetic disorder informative about sleep. Genome Research. 11: 509-11. PMID 11282965 DOI: 10.1101/gr.184301  1
2001 Waleh NS, Apte-Deshpande A, Terao A, Ding J, Kilduff TS. Modulation of the promoter region of prepro-hypocretin by alpha-interferon. Gene. 262: 123-8. PMID 11179675 DOI: 10.1016/S0378-1119(00)00544-8  1
2001 Terao A, Waleh NS, Kilduff TS. The hypocretin/orexin system and the regulation of arousal states Neuroscience News. 4: 4-13.  1
2000 Terao A, Peyron C, Ding J, Wurts SW, Edgar DM, Heller HC, Kilduff TS. Prepro-hypocretin (prepro-orexin) expression is unaffected by short-term sleep deprivation in rats and mice. Sleep. 23: 867-74. PMID 11083595  1
2000 Kilduff TS, Peyron C. The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders. Trends in Neurosciences. 23: 359-65. PMID 10906799 DOI: 10.1016/S0166-2236(00)01594-0  1
2000 Kilduff TS. What rest in flies can tell us about sleep in mammals. Neuron. 26: 295-8. PMID 10839349  1
2000 Kilduff TS. Narcolepsy: A neurodegenerative disease of the hypocretin/orexin system? Trends in Neurosciences. 23: 512. DOI: 10.1016/S0166-2236(00)01699-4  1
1999 Horvath TL, Peyron C, Diano S, Ivanov A, Aston-Jones G, Kilduff TS, van Den Pol AN. Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. The Journal of Comparative Neurology. 415: 145-59. PMID 10545156 DOI: 10.1002/(SICI)1096-9861(19991213)415:2<145::AID-CNE1>3.0.CO;2-2  1
1999 Bitting L, Watson FL, O'Hara BF, Kilduff TS, Heller HC. HSP70 expression is increased during the day in a diurnal animal, the golden-mantled ground squirrel Spermophilus lateralis. Molecular and Cellular Biochemistry. 199: 25-34. PMID 10544948 DOI: 10.1023/A:1006942814185  1
1999 O'Hara BF, Watson FL, Srere HK, Kumar H, Wiler SW, Welch SK, Bitting L, Heller HC, Kilduff TS. Gene expression in the brain across the hibernation cycle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3781-90. PMID 10234010  1
1999 O'Hara BF, Macdonald E, Clegg D, Wiler SW, Andretic R, Cao VH, Miller JD, Heller HC, Kilduff TS. Developmental changes in nicotinic receptor mRNAs and responses to nicotine in the suprachiasmatic nucleus and other brain regions. Brain Research. Molecular Brain Research. 66: 71-82. PMID 10095079 DOI: 10.1016/S0169-328X(99)00004-2  1
1999 Risold PY, Griffond B, Kilduff TS, Sutcliffe JG, Fellmann D. Preprohypocretin (orexin) and prolactin-like immunoreactivity are coexpressed by neurons of the rat lateral hypothalamic area. Neuroscience Letters. 259: 153-6. PMID 10025581 DOI: 10.1016/S0304-3940(98)00906-9  1
1998 Peyron C, Tighe DK, van den Pol AN, de Lecea L, Heller HC, Sutcliffe JG, Kilduff TS. Neurons containing hypocretin (orexin) project to multiple neuronal systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9996-10015. PMID 9822755  1
1998 van den Pol AN, Gao XB, Obrietan K, Kilduff TS, Belousov AB. Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7962-71. PMID 9742163  1
1998 Kilduff TS, Vugrinic C, Lee SL, Milbrandt JD, Mikkelsen JD, O'Hara BF, Heller HC. Characterization of the circadian system of NGFI-A and NGFI-A/NGFI-B deficient mice. Journal of Biological Rhythms. 13: 347-57. PMID 9711509  1
1998 O'Hara BF, Edgar DM, Cao VH, Wiler SW, Heller HC, Kilduff TS, Miller JD. Nicotine and nicotinic receptors in the circadian system. Psychoneuroendocrinology. 23: 161-73. PMID 9621396 DOI: 10.1016/S0306-4530(97)00077-2  1
1998 de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Gautvik VT, Bartlett FS, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proceedings of the National Academy of Sciences of the United States of America. 95: 322-7. PMID 9419374 DOI: 10.1073/pnas.95.1.322  1
1997 O'Hara BF, Watson FL, Andretic R, Wiler SW, Young KA, Bitting L, Heller HC, Kilduff TS. Daily variation of CNS gene expression in nocturnal vs. diurnal rodents and in the developing rat brain. Brain Research. Molecular Brain Research. 48: 73-86. PMID 9379853 DOI: 10.1016/S0169-328X(97)00084-3  1
1995 Welch SK, O'Hara BF, Kilduff TS, Heller HC. Sequence and tissue distribution of a candidate G-coupled receptor cloned from rat hypothalamus. Biochemical and Biophysical Research Communications. 209: 606-13. PMID 7733930 DOI: 10.1006/bbrc.1995.1543  1
1995 O'Hara BF, Andretic R, Heller HC, Carter DB, Kilduff TS. GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions. Brain Research. Molecular Brain Research. 28: 239-50. PMID 7723623 DOI: 10.1016/0169-328X(94)00212-W  1
1995 Clegg DA, O'Hara BF, Heller HC, Kilduff TS. Nicotine administration differentially affects gene expression in the maternal and fetal circadian clock. Brain Research. Developmental Brain Research. 84: 46-54. PMID 7720216 DOI: 10.1016/0165-3806(94)00152-P  1
1994 Bitting L, Sutin EL, Watson FL, Leard LE, O'Hara BF, Heller HC, Kilduff TS. C-fos mRNA increases in the ground squirrel suprachiasmatic nucleus during arousal from hibernation. Neuroscience Letters. 165: 117-21. PMID 8015710 DOI: 10.1016/0304-3940(94)90723-4  1
1994 Leard LE, Macdonald ES, Heller HC, Kilduff TS. Ontogeny of photic-induced c-fos mRNA expression in rat suprachiasmatic nuclei. Neuroreport. 5: 2683-7. PMID 7696632  1
1993 O'Hara BF, Young KA, Watson FL, Heller HC, Kilduff TS. Immediate early gene expression in brain during sleep deprivation: preliminary observations. Sleep. 16: 1-7. PMID 8456228  1
1993 Kilduff TS, Krilowicz B, Milsom WK, Trachsel L, Wang LC. Sleep and mammalian hibernation: homologous adaptations and homologous processes? Sleep. 16: 372-86. PMID 8341898  1
1993 Sutin EL, Dement WC, Heller HC, Kilduff TS. Light-induced gene expression in the suprachiasmatic nucleus of young and aging rats. Neurobiology of Aging. 14: 441-6. PMID 8247226 DOI: 10.1016/0197-4580(93)90102-H  1
1992 Reid MS, Kilduff TS, Romero LM, Florant GL, Dement WC, Heller HC. Monoaminc and metabolite levels in the cerebrospinal fluid of hibernating and euthermic marmots. Journal of Sleep Research. 1: 45-50. PMID 10607025  0.88
1992 Shiromani PJ, Kilduff TS, Bloom FE, McCarley RW. Cholinergically induced REM sleep triggers Fos-like immunoreactivity in dorsolateral pontine regions associated with REM sleep. Brain Research. 580: 351-7. PMID 1504815 DOI: 10.1016/0006-8993(92)90968-F  1
1992 Kilduff TS, Landel HB, Nagy GS, Sutin EL, Dement WC, Heller HC. Melatonin influences Fos expression in the rat suprachiasmatic. Brain Research. Molecular Brain Research. 16: 47-56. PMID 1334199 DOI: 10.1016/0169-328X(92)90192-E  1
1992 Sutin EL, Kilduff TS. Circadian and light-induced expression of immediate early gene mRNAs in the rat suprachiasmatic nucleus. Brain Research. Molecular Brain Research. 15: 281-90. PMID 1331682 DOI: 10.1016/0169-328X(92)90119-V  1
1992 Reid MS, Kilduff TS, Romero LM, Florant GL, Dement WC, Heller HC. Monoamine and metabolite levels in the cerebrospinal fluid of hibernating and euthermic marmots Journal of Sleep Research. 1: 45-50.  1
1991 Haak LL, Mignot E, Kilduff TS, Dement WC, Heller HC. Regional changes in central monoamine and metabolite levels during the hibernation cycle in the golden-mantled ground squirrel. Brain Research. 563: 215-20. PMID 1786534 DOI: 10.1016/0006-8993(91)91536-A  1
1991 Edgar DM, Kilduff TS, Martin CE, Dement WC. Influence of running wheel activity on free-running sleep/wake and drinking circadian rhythms in mice. Physiology & Behavior. 50: 373-8. PMID 1745682 DOI: 10.1016/0031-9384(91)90080-8  1
1990 Kilduff TS, Miller JD, Radeke CM, Sharp FR, Heller HC. 14C-2-deoxyglucose uptake in the ground squirrel brain during entrance to and arousal from hibernation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2463-75. PMID 2376782  1
1990 Dark J, Kilduff TS, Heller HC, Licht P, Zucker I. Suprachiasmatic nuclei influence hibernation rhythms of golden-mantled ground squirrels. Brain Research. 509: 111-8. PMID 2306628 DOI: 10.1016/0006-8993(90)90316-4  1
1990 Nishino S, Mignot E, Kilduff TS, Sakai T, Hayaishi O, Dement WC. Prostaglandin E2 levels in cerebrospinal fluid of normal and narcoleptic dogs. Biological Psychiatry. 28: 904-10. PMID 2268692 DOI: 10.1016/0006-3223(90)90570-R  1
1989 Kilduff TS, Radeke CM, Randall TL, Sharp FR, Heller HC. Suprachiasmatic nucleus: phase-dependent activation during the hibernation cycle. The American Journal of Physiology. 257: R605-12. PMID 2782463  1
1989 Motoyama M, Kilduff TS, Lee BS, Dement WC, McDevitt HO. Restriction fragment length polymorphism in canine narcolepsy. Immunogenetics. 29: 124-6. PMID 2563354 DOI: 10.1007/BF00395862  1
1989 Dean RR, Kilduff TS, Dement WC, Grumet FC. Narcolepsy without unique MHC class II antigen association: studies in the canine model. Human Immunology. 25: 27-35. PMID 2523880 DOI: 10.1016/0198-8859(89)90067-0  1
1988 Kilduff TS, Sharp FR, Heller HC. Progressive activation of paratrigeminal nucleus during entrance to hibernation. The American Journal of Physiology. 255: R178-81. PMID 3394841  1
1987 Bowersox SS, Kilduff TS, Faull KF, Zeller-DeAmicis L, Dement WC, Ciaranello RD. Brain dopamine receptor levels elevated in canine narcolepsy. Brain Research. 402: 44-8. PMID 3828787 DOI: 10.1016/0006-8993(87)91045-6  1
1987 Kilduff TS, Bowersox SS, Faull KF, Zeller-DeAmicis L, Radeke CM, Ciaranello RD, Heller HC, Barchas JD, Dement WC. Modulation of activity of the striatal dopaminergic system during the hibernation cycle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 2732-6. PMID 3625271  1
1987 Holloman JD, Bell JI, Kilduff TS, Dement WC, Guilleminault C, McDevitt HO. HLA-DR restriction-fragment-length polymorphisms in narcolepsy. Journal of Neuroscience Research. 18: 239-44. PMID 2890770 DOI: 10.1002/jnr.490180134  1
1986 Kaitin KI, Kilduff TS, Dement WC. Sleep fragmentation in canine narcolepsy. Sleep. 9: 116-9. PMID 3704433  1
1986 Faull KF, Zeller-DeAmicis LC, Radde L, Bowersox SS, Baker TL, Kilduff TS, Dement WC. Biogenic amine concentrations in the brains of normal and narcoleptic canines: current status. Sleep. 9: 107-10. PMID 3704432  1
1986 Kilduff TS, Bowersox SS, Kaitin KI, Baker TL, Ciaranello RD, Dement WC. Muscarinic cholinergic receptors and the canine model of narcolepsy. Sleep. 9: 102-6. PMID 3704431  1
1986 Bowersox SS, Kilduff TS, Kaitin KI, Dement WC, Ciaranello RD. Brain benzodiazepine receptor characteristics in canine narcolepsy. Sleep. 9: 111-5. PMID 3010425  1
1986 Kaitin KI, Kilduff TS, Dement WC. Evidence for excessive sleepiness in canine narcoleptics. Electroencephalography and Clinical Neurophysiology. 64: 447-54. PMID 2428595 DOI: 10.1016/0013-4694(86)90078-7  1
1983 Kilduff TS, George CP, Sharp FR, Heller HC. Metabolic activation of the brachium conjunctivum during induced hypothermia. Brain Research. 269: 168-71. PMID 6871697 DOI: 10.1016/0006-8993(83)90976-9  1
1983 Sharp FR, Kilduff TS, Bzorgchami S, Heller HC, Ryan AF. The relationship of local cerebral glucose utilization to optical density ratios. Brain Research. 263: 97-103. PMID 6839171 DOI: 10.1016/0006-8993(83)91204-0  1
1983 Kilduff TS, Sharp FR, Heller HC. Relative 2-deoxyglucose uptake of the paratrigeminal nucleus increases during hibernation. Brain Research. 262: 117-23. PMID 6831223 DOI: 10.1016/0006-8993(83)90475-4  1
1982 George CP, Kilduff TS, Sharp FR, Heller HC. Autoradiographic patterns of hippocampal metabolism during induced hypothermia. Neuroscience Letters. 34: 233-9. PMID 7162705 DOI: 10.1016/0304-3940(82)90181-1  1
1982 Kilduff TS, Sharp FR, Heller HC. [14C]2-deoxyglucose uptake in ground squirrel brain during hibernation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 143-57. PMID 6278102  1
1981 Sharp FR, Kilduff TS. The 2-deoxyglucose neuroanatomical mapping technique Trends in Neurosciences. 4: 144-148. DOI: 10.1016/0166-2236(81)90048-5  1
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