Darleen A. Sandoval, Ph.D. - Publications

Affiliations: 
Arizona State University, Tempe, AZ, United States 

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Seeley RJ, Sandoval DA. Targeting the brain as a cure for type 2 diabetes. Nature Medicine. 22: 709-11. PMID 27387884 DOI: 10.1038/Nm.4137  1
2016 Frikke-Schmidt H, O'Rourke RW, Lumeng CN, Sandoval DA, Seeley RJ. Does bariatric surgery improve adipose tissue function? Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. PMID 27272117 DOI: 10.1111/Obr.12429  1
2016 Sandoval D. Roux-en-Y Gastric Bypass and Vertical Sleeve Gastrectomy: Divergent Pathways to Improved Glucose Homeostasis Gastroenterology. 150: 309-312. DOI: 10.1053/J.Gastro.2015.12.021  1
2015 Kohli R, Myronovych A, Tan BK, Salazar-Gonzalez RM, Miles L, Zhang W, Oehrle M, Sandoval DA, Ryan KK, Seeley RJ, Setchell KD. Bile Acid Signaling: Mechanism for Bariatric Surgery, Cure for NASH? Digestive Diseases (Basel, Switzerland). 33: 440-6. PMID 26045281 DOI: 10.1159/000371699  1
2015 Sandoval DA, D'Alessio DA. Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease. Physiological Reviews. 95: 513-48. PMID 25834231 DOI: 10.1152/Physrev.00013.2014  1
2015 Arble DM, Holland J, Ottaway N, Sorrell J, Pressler JW, Morano R, Woods SC, Seeley RJ, Herman JP, Sandoval DA, Perez-Tilve D. The melanocortin-4 receptor integrates circadian light cues and metabolism. Endocrinology. 156: 1685-91. PMID 25730108 DOI: 10.1210/En.2014-1937  1
2015 Finan B, Yang B, Ottaway N, Smiley DL, Ma T, Clemmensen C, Chabenne J, Zhang L, Habegger KM, Fischer K, Campbell JE, Sandoval D, Seeley RJ, Bleicher K, Uhles S, et al. A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Nature Medicine. 21: 27-36. PMID 25485909 DOI: 10.1038/Nm.3761  1
2015 Arble DM, Sandoval DA, Seeley RJ. Mechanisms underlying weight loss and metabolic improvements in rodent models of bariatric surgery. Diabetologia. 58: 211-20. PMID 25374275 DOI: 10.1007/S00125-014-3433-3  1
2015 Pressler JW, Haller A, Sorrell J, Wang F, Seeley RJ, Tso P, Sandoval DA. Vertical sleeve gastrectomy restores glucose homeostasis in apolipoprotein A-IV KO mice. Diabetes. 64: 498-507. PMID 25157093 DOI: 10.2337/Db14-0825  1
2015 Obici S, Magrisso IJ, Ghazarian AS, Shirazian A, Miller JR, Loyd CM, Begg DP, Krawczewski Carhuatanta KA, Haas MK, Davis JF, Woods SC, Sandoval DA, Seeley RJ, Goodyear LJ, Pothos EN, et al. Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation Molecular Metabolism. DOI: 10.1016/j.molmet.2015.07.003  1
2015 Sandoval D, Sisley SR. Brain GLP-1 and insulin sensitivity Molecular and Cellular Endocrinology. 418: 27-32. DOI: 10.1016/J.Mce.2015.02.017  1
2014 Mul JD, Begg DP, Haller AM, Pressler JW, Sorrell J, Woods SC, Farese RV, Seeley RJ, Sandoval DA. MGAT2 deficiency and vertical sleeve gastrectomy have independent metabolic effects in the mouse. American Journal of Physiology. Endocrinology and Metabolism. 307: E1065-72. PMID 25315695 DOI: 10.1152/Ajpendo.00376.2014  1
2014 Sisley S, Smith K, Sandoval DA, Seeley RJ. Differences in acute anorectic effects of long-acting GLP-1 receptor agonists in rats. Peptides. 58: 1-6. PMID 24879927 DOI: 10.1016/j.peptides.2014.05.008  1
2014 Smith EP, An Z, Wagner C, Lewis AG, Cohen EB, Li B, Mahbod P, Sandoval D, Perez-Tilve D, Tamarina N, Philipson LH, Stoffers DA, Seeley RJ, D'Alessio DA. The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs. Cell Metabolism. 19: 1050-7. PMID 24836562 DOI: 10.1016/J.Cmet.2014.04.005  1
2014 Sisley S, Gutierrez-Aguilar R, Scott M, D'Alessio DA, Sandoval DA, Seeley RJ. Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. The Journal of Clinical Investigation. 124: 2456-63. PMID 24762441 DOI: 10.1172/Jci72434  1
2014 Ryan KK, Tremaroli V, Clemmensen C, Kovatcheva-Datchary P, Myronovych A, Karns R, Wilson-Pérez HE, Sandoval DA, Kohli R, Bäckhed F, Seeley RJ. FXR is a molecular target for the effects of vertical sleeve gastrectomy. Nature. 509: 183-8. PMID 24670636 DOI: 10.1038/Nature13135  1
2014 Sandoval D. Old dog, new trick: A direct role for leptin in regulating microbiota composition Endocrinology. 155: 653-655. PMID 24564414 DOI: 10.1210/En.2014-1078  1
2014 Chambers AP, Smith EP, Begg DP, Grayson BE, Sisley S, Greer T, Sorrell J, Lemmen L, LaSance K, Woods SC, Seeley RJ, D'Alessio DA, Sandoval DA. Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy. American Journal of Physiology. Endocrinology and Metabolism. 306: E424-32. PMID 24368666 DOI: 10.1152/Ajpendo.00469.2013  1
2014 Li B, Matter EK, Hoppert HT, Grayson BE, Seeley RJ, Sandoval DA. Identification of optimal reference genes for RT-qPCR in the rat hypothalamus and intestine for the study of obesity. International Journal of Obesity (2005). 38: 192-7. PMID 23736358 DOI: 10.1038/Ijo.2013.86  1
2014 Heppner KM, Piechowski CL, Müller A, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, DiMarchi R, Biebermann H, Tschöp MH, Sandoval DA, Perez-Tilve D. Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors Diabetes. 63: 122-131. DOI: 10.2337/db13-0414  1
2013 Bielohuby M, Sisley S, Sandoval D, Herbach N, Zengin A, Fischereder M, Menhofer D, Stoehr BJ, Stemmer K, Wanke R, Tschöp MH, Seeley RJ, Bidlingmaier M. Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets. American Journal of Physiology. Endocrinology and Metabolism. 305: E1059-70. PMID 23982154 DOI: 10.1152/Ajpendo.00208.2013  1
2013 Sandoval D, Dunki-Jacobs A, Sorrell J, Seeley RJ, D'Alessio DD. Impact of intestinal electrical stimulation on nutrient-induced GLP-1 secretion in vivo. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 25: 700-5. PMID 23663526 DOI: 10.1111/Nmo.12152  1
2013 Chambers AP, Sandoval DA, Seeley RJ. Integration of satiety signals by the central nervous system. Current Biology : Cb. 23: R379-88. PMID 23660361 DOI: 10.1016/J.Cub.2013.03.020  1
2013 Mul JD, Begg DP, Barrera JG, Li B, Matter EK, D'Alessio DA, Woods SC, Seeley RJ, Sandoval DA. High-fat diet changes the temporal profile of GLP-1 receptor-mediated hypophagia in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 305: R68-77. PMID 23616105 DOI: 10.1152/Ajpregu.00588.2012  1
2013 Arble DM, Sandoval DA. CNS control of glucose metabolism: response to environmental challenges. Frontiers in Neuroscience. 7: 20. PMID 23550218 DOI: 10.3389/Fnins.2013.00020  1
2013 Wilson-Pérez HE, Chambers AP, Ryan KK, Li B, Sandoval DA, Stoffers D, Drucker DJ, Pérez-Tilve D, Seeley RJ. Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like Peptide 1 receptor deficiency. Diabetes. 62: 2380-5. PMID 23434938 DOI: 10.2337/Db12-1498  1
2013 Grayson BE, Seeley RJ, Sandoval DA. Wired on sugar: the role of the CNS in the regulation of glucose homeostasis. Nature Reviews. Neuroscience. 14: 24-37. PMID 23232606 DOI: 10.1038/Nrn3409  1
2013 Chambers AP, Kirchner H, Wilson-Perez HE, Willency JA, Hale JE, Gaylinn BD, Thorner MO, Pfluger PT, Gutierrez JA, Tschöp MH, Sandoval DA, Seeley RJ. The effects of vertical sleeve gastrectomy in rodents are ghrelin independent. Gastroenterology. 144: 50-52.e5. PMID 22995675 DOI: 10.1053/J.Gastro.2012.09.009  1
2013 Wilson-Pérez HE, Chambers AP, Sandoval DA, Stefater MA, Woods SC, Benoit SC, Seeley RJ. The effect of vertical sleeve gastrectomy on food choice in rats. International Journal of Obesity (2005). 37: 288-95. PMID 22334194 DOI: 10.1038/Ijo.2012.18  1
2012 Sandoval D, Barrera JG, Stefater MA, Sisley S, Woods SC, D'Alessio DD, Seeley RJ. The anorectic effect of GLP-1 in rats is nutrient dependent. Plos One. 7: e51870. PMID 23284795 DOI: 10.1371/Journal.Pone.0051870  1
2012 Sandoval DA, Ryan KK, de Kloet AD, Woods SC, Seeley RJ. Female rats are relatively more sensitive to reduced lipid versus reduced carbohydrate availability. Nutrition & Diabetes. 2: e27. PMID 23169552 DOI: 10.1038/Nutd.2011.23  1
2012 Chambers AP, Wilson-Perez HE, McGrath S, Grayson BE, Ryan KK, D'Alessio DA, Woods SC, Sandoval DA, Seeley RJ. Effect of vertical sleeve gastrectomy on food selection and satiation in rats. American Journal of Physiology. Endocrinology and Metabolism. 303: E1076-84. PMID 22932782 DOI: 10.1152/Ajpendo.00211.2012  1
2012 Kim DH, Sartor MA, Bain JR, Sandoval D, Stevens RD, Medvedovic M, Newgard CB, Woods SC, Seeley RJ. Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium. Diabetes. 61: 2299-310. PMID 22733798 DOI: 10.2337/Db11-1579  1
2012 Stefater MA, Wilson-Pérez HE, Chambers AP, Sandoval DA, Seeley RJ. All bariatric surgeries are not created equal: insights from mechanistic comparisons. Endocrine Reviews. 33: 595-622. PMID 22550271 DOI: 10.1210/Er.2011-1044  1
2012 Mul JD, Begg DP, Alsters SI, van Haaften G, Duran KJ, D'Alessio DA, le Roux CW, Woods SC, Sandoval DA, Blakemore AI, Cuppen E, van Haelst MM, Seeley RJ. Effect of vertical sleeve gastrectomy in melanocortin receptor 4-deficient rats. American Journal of Physiology. Endocrinology and Metabolism. 303: E103-10. PMID 22535749 DOI: 10.1152/Ajpendo.00159.2012  1
2011 Sandoval D. Bariatric surgeries: Beyond restriction and malabsorption International Journal of Obesity. 35: S45-S49. PMID 21912388 DOI: 10.1038/Ijo.2011.148  1
2011 Seeley RJ, Sandoval DA. Neuroscience: weight loss through smoking. Nature. 475: 176-7. PMID 21753841 DOI: 10.1038/475176A  1
2011 Chambers AP, Jessen L, Ryan KK, Sisley S, Wilson-Pérez HE, Stefater MA, Gaitonde SG, Sorrell JE, Toure M, Berger J, D'Alessio DA, Woods SC, Seeley RJ, Sandoval DA. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology. 141: 950-8. PMID 21699789 DOI: 10.1053/J.Gastro.2011.05.050  1
2011 Stefater MA, Sandoval DA, Chambers AP, Wilson-Pérez HE, Hofmann SM, Jandacek R, Tso P, Woods SC, Seeley RJ. Sleeve gastrectomy in rats improves postprandial lipid clearance by reducing intestinal triglyceride secretion. Gastroenterology. 141: 939-949.e1-4. PMID 21699773 DOI: 10.1053/J.Gastro.2011.05.008  1
2011 Sisley S, Sandoval D. Hypothalamic control of energy and glucose metabolism Reviews in Endocrine and Metabolic Disorders. 12: 219-233. PMID 21695389 DOI: 10.1007/S11154-011-9189-X  1
2011 Chambers AP, Stefater MA, Wilson-Perez HE, Jessen L, Sisley S, Ryan KK, Gaitonde S, Sorrell JE, Toure M, Berger J, D'Alessio DA, Sandoval DA, Seeley RJ, Woods SC. Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. Physiology & Behavior. 105: 120-3. PMID 21683726 DOI: 10.1016/J.Physbeh.2011.05.026  1
2011 Barrera JG, Sandoval DA, D'Alessio DA, Seeley RJ. GLP-1 and energy balance: an integrated model of short-term and long-term control. Nature Reviews. Endocrinology. 7: 507-16. PMID 21647189 DOI: 10.1038/Nrendo.2011.77  1
2011 Tong J, Sandoval DA. Is the GLP-1 system a viable therapeutic target for weight reduction? Reviews in Endocrine & Metabolic Disorders. 12: 187-95. PMID 21336840 DOI: 10.1007/S11154-011-9170-8  1
2010 Sandoval DA, Seeley RJ. Medicine. The microbes made me eat it. Science (New York, N.Y.). 328: 179-80. PMID 20378804 DOI: 10.1126/Science.1188876  1
2010 Stefater MA, Pérez-Tilve D, Chambers AP, Wilson-Pérez HE, Sandoval DA, Berger J, Toure M, Tschöp M, Woods SC, Seeley RJ. Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity. Gastroenterology. 138: 2426-36, 2436.e1-3. PMID 20226189 DOI: 10.1053/J.Gastro.2010.02.059  1
2009 Sandoval DA, Obici S, Seeley RJ. Targeting the CNS to treat type 2 diabetes. Nature Reviews. Drug Discovery. 8: 386-98. PMID 19404312 DOI: 10.1038/Nrd2874  1
2009 Cota D, Sandoval DA, Olivieri M, Prodi E, D'Alessio DA, Woods SC, Seeley RJ, Obici S. Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism. Obesity (Silver Spring, Md.). 17: 1641-5. PMID 19325539 DOI: 10.1038/Oby.2009.84  1
2008 Kim DH, Sandoval D, Reed JA, Matter EK, Tolod EG, Woods SC, Seeley RJ. The role of GM-CSF in adipose tissue inflammation. American Journal of Physiology. Endocrinology and Metabolism. 295: E1038-46. PMID 18765677 DOI: 10.1152/Ajpendo.00061.2008  1
2008 Sandoval D. CNS GLP-1 regulation of peripheral glucose homeostasis Physiology and Behavior. 94: 670-674. PMID 18508100 DOI: 10.1016/J.Physbeh.2008.04.018  1
2008 Sandoval DA, Bagnol D, Woods SC, D'Alessio DA, Seeley RJ. Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. Diabetes. 57: 2046-54. PMID 18487451 DOI: 10.2337/Db07-1824  1
2008 Gustavson SM, Sandoval DA, Ertl AC, Bao S, Raj SR, Davis SN. Stimulation of both type I and type II corticosteroid receptors blunts counterregulatory responses to subsequent hypoglycemia in healthy man. American Journal of Physiology. Endocrinology and Metabolism. 294: E506-12. PMID 18182467 DOI: 10.1152/Ajpendo.00589.2007  1
2008 Sandoval D, Cota D, Seeley RJ. The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation. Annual Review of Physiology. 70: 513-35. PMID 17988209 DOI: 10.1146/Annurev.Physiol.70.120806.095256  1
2007 Sandoval DA, Gong B, Davis SN. Forebrain and hindbrain effects of ethanol on counterregulatory responses to hypoglycemia in conscious rats. Metabolism: Clinical and Experimental. 56: 1623-8. PMID 17998012 DOI: 10.1016/J.Metabol.2007.06.031  1
2007 Sandoval DA, Gong B, Davis SN. Antecedent short-term central nervous system administration of estrogen and progesterone alters counterregulatory responses to hypoglycemia in conscious male rats. American Journal of Physiology. Endocrinology and Metabolism. 293: E1511-6. PMID 17940215 DOI: 10.1152/Ajpendo.00340.2007  1
2006 Sandoval DA, Davis SN. Metabolic consequences of exercise-associated autonomic failure. Exercise and Sport Sciences Reviews. 34: 72-6. PMID 16672804 DOI: 10.1249/00003677-200604000-00006  1
2006 Sandoval DA, Guy DL, Richardson MA, Ertl AC, Davis SN. Acute, same-day effects of antecedent exercise on counterregulatory responses to subsequent hypoglycemia in type 1 diabetes mellitus. American Journal of Physiology. Endocrinology and Metabolism. 290: E1331-8. PMID 16449302 DOI: 10.1152/Ajpendo.00283.2005  1
2006 Guy DLA, Sandoval DA, Davis SN. Hypoglycemia in Diabetes Clinical Diabetes. 119-128. DOI: 10.1016/B978-1-4160-0273-4.50015-1  1
2005 D'Alessio DA, Sandoval DA, Seeley RJ. New ways in which GLP-1 can regulate glucose homeostasis. The Journal of Clinical Investigation. 115: 3406-8. PMID 16322789 DOI: 10.1172/Jci27207  1
2005 Guy DA, Sandoval D, Richardson MA, Tate D, Davis SN. Effects of glycemic control on target organ responses to epinephrine in type 1 diabetes American Journal of Physiology - Endocrinology and Metabolism. 289: E258-E265. PMID 15784645 DOI: 10.1152/Ajpendo.00311.2004  1
2005 Guy DA, Sandoval D, Richardson MA, Tate D, Flakoll PJ, Davis SN. Differing physiological effects of epinephrine in type 1 diabetes and nondiabetic humans American Journal of Physiology - Endocrinology and Metabolism. 288: E178-E186. PMID 15585598 DOI: 10.1152/Ajpendo.00310.2004  1
2005 Sandoval DA, Ping L, Neill RA, Gong B, Walsh K, Davis SN. Brain region-dependent effects of dexamethasone on counterregulatory responses to hypoglycemia in conscious rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R413-9. PMID 15486094 DOI: 10.1152/Ajpregu.00674.2003  1
2004 Sandoval DA, Guy DL, Richardson MA, Ertl AC, Davis SN. Effects of low and moderate antecedent exercise on counterregulatory responses to subsequent hypoglycemia in type 1 diabetes. Diabetes. 53: 1798-806. PMID 15220204 DOI: 10.2337/Diabetes.53.7.1798  1
2004 Sandoval DA, Ping L, Neill RA, Morrey S, Davis SN. The effects of dehydroepiandrosterone sulfate on counterregulatory responses during repeated hypoglycemia in conscious normal rats. Diabetes. 53: 679-86. PMID 14988252 DOI: 10.2337/Diabetes.53.3.679  1
2004 Sandoval DA, Davis SN. Hypoglycemic Associated Autonomic Dysfunction Primer On the Autonomic Nervous System: Second Edition. 397-400. DOI: 10.1016/B978-012589762-4/50108-0  1
2003 Sandoval DA, Galassetti P, Tate D, Neill A, Davis SN. Leptin responses to antecedent exercise and hypoglycemia in healthy and type 1 diabetes mellitus men and women. Journal of Diabetes and Its Complications. 17: 301-6. PMID 14583173 DOI: 10.1016/S1056-8727(02)00243-X  1
2003 Sandoval DA, Ping L, Neill AR, Morrey S, Davis SN. Cortisol acts through central mechanisms to blunt counterregulatory responses to hypoglycemia in conscious rats. Diabetes. 52: 2198-204. PMID 12941757 DOI: 10.2337/Diabetes.52.9.2198  1
2003 Sandoval DA, Ertl AC, Richardson MA, Tate DB, Davis SN. Estrogen blunts neuroendocrine and metabolic responses to hypoglycemia. Diabetes. 52: 1749-55. PMID 12829642 DOI: 10.2337/Diabetes.52.7.1749  1
2003 Sandoval DA, Matt KS. Effects of the oral contraceptive pill cycle on physiological responses to hypoxic exercise. High Altitude Medicine & Biology. 4: 61-72. PMID 12713713 DOI: 10.1089/152702903321488997  1
2003 Sandoval DA, Davis SN. Leptin: metabolic control and regulation. Journal of Diabetes and Its Complications. 17: 108-13. PMID 12614978 DOI: 10.1016/S1056-8727(02)00167-8  1
2002 Diedrich L, Sandoval D, Davis SN. Hypoglycemia associated autonomic failure Clinical Autonomic Research. 12: 358-365. PMID 12420080 DOI: 10.1007/S10286-002-0035-9  1
2002 Sandoval DA, Matt KS. Gender differences in the endocrine and metabolic responses to hypoxic exercise. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 504-12. PMID 11796657 DOI: 10.1152/Japplphysiol.00526.2001  1
2001 Sandoval DA, Maes DP, D'Acquisto L, Icenogle M, Roach RC. Oral contraceptives, exercise, and acute mountain sickness in women. Aviation, Space, and Environmental Medicine. 72: 733-8. PMID 11506235  1
2000 Roach RC, Maes D, Sandoval D, Robergs RA, Icenogle M, Hinghofer-Szalkay H, Lium D, Loeppky JA. Exercise exacerbates acute mountain sickness at simulated high altitude Journal of Applied Physiology. 88: 581-585. PMID 10658026 DOI: 10.1152/Jappl.2000.88.2.581  1
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