| Year |
Citation |
Score |
| 2024 |
Naguib S, Torres ER, Lopez-Lee C, Fan L, Bhagwat M, Norman K, Lee SI, Zhu J, Ye P, Wong MY, Patel T, Mok SA, Luo W, Sinha S, Zhao M, ... ... Gan L, et al. - mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition. Biorxiv : the Preprint Server For Biology. PMID 38712164 DOI: 10.1101/2024.04.25.591140 |
0.684 |
|
| 2023 |
Luo W, Chen H, Fan L, Guo Q, Wong MY, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B, Lopez-Lee C, Huang Y, Amin S, Mok SA, ... ... Gan L, et al. DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. Research Square. PMID 37961627 DOI: 10.21203/rs.3.rs-3454358/v1 |
0.311 |
|
| 2023 |
Chen H, Fan L, Guo Q, Wong MY, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B, Lopez-Lee C, Huang Y, Amin S, Patel T, Mok SA, ... ... Gan L, et al. DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. Biorxiv : the Preprint Server For Biology. PMID 37961594 DOI: 10.1101/2023.10.26.563970 |
0.311 |
|
| 2023 |
Lopez-Lee C, Kodama L, Fan L, Wong MY, Foxe NR, Jiaz L, Yu F, Ye P, Zhu J, Norman K, Torres ER, Kim RD, Mousa GA, Dubal D, Liddelow S, ... ... Gan L, et al. Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging. Biorxiv : the Preprint Server For Biology. PMID 37781600 DOI: 10.1101/2023.09.19.558439 |
0.725 |
|
| 2023 |
Das M, Mao W, Voskobiynyk Y, Necula D, Lew I, Petersen C, Zahn A, Yu GQ, Yu X, Smith N, Sayed F, Gan L, Paz JT, Mucke L. Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models. Neurobiology of Disease. 106263. PMID 37591465 DOI: 10.1016/j.nbd.2023.106263 |
0.554 |
|
| 2022 |
Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Hüttenhain R, Kauwe G, Mercedes M, Sweetland-Martin L, Chen X, Mok SA, Wong MY, ... ... Gan L, et al. Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration. Cell. PMID 35063084 DOI: 10.1016/j.cell.2021.12.041 |
0.306 |
|
| 2020 |
Limbad C, Oron TR, Alimirah F, Davalos AR, Tracy TE, Gan L, Desprez PY, Campisi J. Astrocyte senescence promotes glutamate toxicity in cortical neurons. Plos One. 15: e0227887. PMID 31945125 DOI: 10.1371/Journal.Pone.0227887 |
0.406 |
|
| 2020 |
Chen X, Li Y, Wang C, Tang Y, Mok SA, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL, Gestwicki JE, Arkin M, Cuervo AM, Gan L. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Molecular Neurodegeneration. 15: 2. PMID 31906970 DOI: 10.1186/S13024-019-0354-0 |
0.364 |
|
| 2019 |
Tracy T, Claiborn KC, Gan L. Regulation of Tau Homeostasis and Toxicity by Acetylation. Advances in Experimental Medicine and Biology. 1184: 47-55. PMID 32096027 DOI: 10.1007/978-981-32-9358-8_4 |
0.409 |
|
| 2019 |
Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC, Clelland CD, Cheng Z, Yu G, Li Q, Kosik KS, ... Gan L, et al. Microglial microRNAs mediate sex-specific responses to tau pathology. Nature Neuroscience. PMID 31873194 DOI: 10.1038/S41593-019-0560-7 |
0.351 |
|
| 2019 |
Lin LC, Nana AL, Hepker M, Hwang JL, Gaus SE, Spina S, Cosme CG, Gan L, Grinberg LT, Geschwind DH, Coppola G, Rosen HJ, Miller BL, Seeley WW. Preferential tau aggregation in von Economo neurons and fork cells in frontotemporal lobar degeneration with specific MAPT variants. Acta Neuropathologica Communications. 7: 159. PMID 31640778 DOI: 10.1186/S40478-019-0809-0 |
0.37 |
|
| 2019 |
Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, ... ... Gan L, et al. A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies. Stem Cell Reports. PMID 31631020 DOI: 10.1016/J.Stemcr.2019.09.006 |
0.34 |
|
| 2019 |
Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, ... ... Gan L, et al. Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron. PMID 31542321 DOI: 10.1016/J.Neuron.2019.08.008 |
0.35 |
|
| 2019 |
Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, ... ... Gan L, et al. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nature Genetics. 51: 1252-1262. PMID 31367015 DOI: 10.1038/S41588-019-0472-1 |
0.317 |
|
| 2019 |
Kodama L, Gan L. Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases? Trends in Molecular Medicine. PMID 31171460 DOI: 10.1016/j.molmed.2019.05.001 |
0.339 |
|
| 2019 |
Mucke L, Akassoglou K, Das M, Gan L, Ho K, Merlini M, Orr A, Rafalski VA, Ryu JK, Sayed F, Seeley WW, Yu G. ASTROGLIAL AND MICROGLIAL MODULATION OF NEURAL FUNCTIONS IN MODELS OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P188. DOI: 10.1016/J.Jalz.2019.06.4393 |
0.537 |
|
| 2019 |
Theofilas P, Hayath M, Wang C, Butler D, McAllen S, Arkin M, Gestwicki J, Cuervo AM, Kayed R, Karch CM, Temple S, Gan L, Grinberg LT. P3-200: Tau-Mediated Cell Death Mechanisms In Mapt V337M Ipsc-Derived Human Neurons Alzheimers & Dementia. 15: 1006. DOI: 10.1016/J.Jalz.2019.06.3229 |
0.327 |
|
| 2018 |
Snyder HM, Carare RO, DeKosky ST, de Leon MJ, Dykxhoorn D, Gan L, Gardner R, Hinds SR, Jaffee M, Lamb BT, Landau S, Manley G, McKee A, Perl D, Schneider JA, et al. Military-related risk factors for dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30415806 DOI: 10.1016/J.Jalz.2018.08.011 |
0.323 |
|
| 2018 |
Gan L, Cookson MR, Petrucelli L, La Spada AR. Converging pathways in neurodegeneration, from genetics to mechanisms. Nature Neuroscience. 21: 1300-1309. PMID 30258237 DOI: 10.1038/S41593-018-0237-7 |
0.322 |
|
| 2018 |
Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C, Zhan L, Cooper YA, Davalos D, Akassoglou K, Coppola G, ... Gan L, et al. Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. Proceedings of the National Academy of Sciences of the United States of America. PMID 30232263 DOI: 10.1073/Pnas.1811411115 |
0.422 |
|
| 2018 |
Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, ... ... Gan L, et al. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 174: 505-520. PMID 30053424 DOI: 10.1016/J.Cell.2018.06.016 |
0.516 |
|
| 2018 |
Tracy TE, Gan L. Tau-mediated synaptic and neuronal dysfunction in neurodegenerative disease. Current Opinion in Neurobiology. 51: 134-138. PMID 29753269 DOI: 10.1016/J.Conb.2018.04.027 |
0.389 |
|
| 2018 |
Martinez-Losa M, Tracy TE, Ma K, Verret L, Clemente-Perez A, Khan AS, Cobos I, Ho K, Gan L, Mucke L, Alvarez-Dolado M, Palop JJ. Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease. Neuron. PMID 29551491 DOI: 10.1016/J.Neuron.2018.02.029 |
0.729 |
|
| 2018 |
Min SW, Sohn PD, Li Y, Devidze N, Johnson JR, Krogan NJ, Masliah E, Mok SA, Gestwicki JE, Gan L. SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29540553 DOI: 10.1523/Jneurosci.2369-17.2018 |
0.395 |
|
| 2018 |
Udeochu J, Sayed FA, Gan L. TREM2 and Amyloid Beta: A Love-Hate Relationship. Neuron. 97: 991-993. PMID 29518360 DOI: 10.1016/J.Neuron.2018.02.018 |
0.339 |
|
| 2018 |
Ehrenberg AJ, Petersen C, Morales DO, Theofilas P, Hepker M, Li AN, Cosme CG, Suemoto CK, Alho AT, Leite REP, Rodriguez RD, Farfel JM, Ferretti-Rebustini REdL, Nascimento CF, Nitrini R, ... ... Gan L, et al. P1-237: Post-Translational Modifications Of Tau In Alzheimer'S Disease: A Postmortem Study In Humans Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.242 |
0.376 |
|
| 2017 |
Krencik R, Seo K, van Asperen JV, Basu N, Cvetkovic C, Barlas S, Chen R, Ludwig C, Wang C, Ward ME, Gan L, Horner PJ, Rowitch DH, Ullian EM. Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. Stem Cell Reports. 9: 1745-1753. PMID 29198827 DOI: 10.1016/J.Stemcr.2017.10.026 |
0.306 |
|
| 2017 |
Wang C, Telpoukhovskaia MA, Bahr BA, Chen X, Gan L. Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases. Current Opinion in Neurobiology. 48: 52-58. PMID 29028540 DOI: 10.1016/j.conb.2017.09.005 |
0.385 |
|
| 2017 |
Boselli M, Lee BH, Robert J, Prado MA, Min SW, Cheng C, Silva MC, Seong C, Elsasser S, Hatle KM, Gahman TC, Gygi SP, Haggarty SJ, Gan L, King RW, et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. The Journal of Biological Chemistry. PMID 28972160 DOI: 10.1074/Jbc.M117.815126 |
0.354 |
|
| 2017 |
Wang C, Ward ME, Chen R, Liu K, Tracy TE, Chen X, Xie M, Sohn PD, Ludwig C, Meyer-Franke A, Karch CM, Ding S, Gan L. Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. Stem Cell Reports. PMID 28966121 DOI: 10.1016/J.Stemcr.2017.08.019 |
0.331 |
|
| 2017 |
Krabbe G, Minami SS, Etchegaray JI, Taneja P, Djukic B, Davalos D, Le D, Lo I, Zhan L, Reichert MC, Sayed F, Merlini M, Ward ME, Perry DC, Lee SE, ... ... Gan L, et al. Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28438992 DOI: 10.1073/Pnas.1700477114 |
0.353 |
|
| 2017 |
Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, ... ... Gan L, et al. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Science Translational Medicine. 9. PMID 28404863 DOI: 10.1126/Scitranslmed.Aah5642 |
0.324 |
|
| 2017 |
Tracy TE, Gan L. Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28083916 DOI: 10.1002/Bies.201600224 |
0.381 |
|
| 2016 |
Wes PD, Sayed FA, Bard F, Gan L. Targeting microglia for the treatment of Alzheimer's Disease. Glia. PMID 27100611 DOI: 10.1002/Glia.22988 |
0.406 |
|
| 2016 |
Tracy TE, Sohn PD, Minami SS, Wang C, Min SW, Li Y, Zhou Y, Le D, Lo I, Ponnusamy R, Cong X, Schilling B, Ellerby LM, Huganir RL, Gan L. Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss. Neuron. PMID 27041503 DOI: 10.1016/J.Neuron.2016.03.005 |
0.383 |
|
| 2015 |
Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, ... ... Gan L, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nature Medicine. PMID 26390242 DOI: 10.1038/Nm.3951 |
0.422 |
|
| 2015 |
Gan L. Inge grundke-iqbal award for Alzheimer’s research: Progranulin protects against amyloid b deposition and toxicity in Alzheimer's disease mouse models Alzheimers & Dementia. 11: 216. DOI: 10.1016/J.Jalz.2015.07.235 |
0.379 |
|
| 2014 |
Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV, Gan L. Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models. Nature Medicine. 20: 1157-64. PMID 25261995 DOI: 10.1038/nm.3672 |
0.615 |
|
| 2014 |
Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, ... ... Gan L, et al. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of Experimental Medicine. 211: 1937-45. PMID 25155018 DOI: 10.1084/Jem.20140214 |
0.363 |
|
| 2013 |
Min SW, Sohn PD, Cho SH, Swanson RA, Gan L. Sirtuins in neurodegenerative diseases: an update on potential mechanisms. Frontiers in Aging Neuroscience. 5: 53. PMID 24093018 DOI: 10.3389/Fnagi.2013.00053 |
0.344 |
|
| 2013 |
Grinberg LT, Wang X, Wang C, Sohn PD, Theofilas P, Sidhu M, Arevalo JB, Heinsen H, Huang EJ, Rosen H, Miller BL, Gan L, Seeley WW. Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation. Acta Neuropathologica. 125: 581-93. PMID 23371364 DOI: 10.1007/S00401-013-1080-2 |
0.355 |
|
| 2012 |
Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/Jci63113 |
0.323 |
|
| 2012 |
Wang C, Sun B, Zhou Y, Grubb A, Gan L. Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein. The Journal of Biological Chemistry. 287: 39834-41. PMID 23024364 DOI: 10.1074/jbc.M112.371641 |
0.402 |
|
| 2012 |
Pappas DJ, Gabatto PA, Oksenberg D, Khankhanian P, Baranzini SE, Gan L, Oksenberg JR. Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules. Neuroscience. 226: 10-20. PMID 22986168 DOI: 10.1016/j.neuroscience.2012.09.007 |
0.317 |
|
| 2012 |
Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L. Selective targeting of microglia by quantum dots. Journal of Neuroinflammation. 9: 22. PMID 22272874 DOI: 10.1186/1742-2094-9-22 |
0.532 |
|
| 2011 |
Kauppinen TM, Suh SW, Higashi Y, Berman AE, Escartin C, Won SJ, Wang C, Cho SH, Gan L, Swanson RA. Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β. Journal of Neuroinflammation. 8: 152. PMID 22051244 DOI: 10.1186/1742-2094-8-152 |
0.388 |
|
| 2011 |
Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ, Chen J. Protective effects and mechanisms of sirtuins in the nervous system. Progress in Neurobiology. 95: 373-95. PMID 21930182 DOI: 10.1016/j.pneurobio.2011.09.001 |
0.345 |
|
| 2011 |
Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, Ransohoff RM, Gan L. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. The Journal of Biological Chemistry. 286: 32713-22. PMID 21771791 DOI: 10.1074/Jbc.M111.254268 |
0.438 |
|
| 2011 |
Sun B, Gan L. Manipulation of gene expression in the central nervous system with lentiviral vectors. Methods in Molecular Biology (Clifton, N.J.). 670: 155-68. PMID 20967590 DOI: 10.1007/978-1-60761-744-0_12 |
0.345 |
|
| 2011 |
Gan L, Min S, Cho S, Zhou Y, Haroutunian V, Seeley B, Huang E, Shen Y, Masliah E, Cole P, Ott M. Acetylation of tau contributes to tau accumulation and dysfunction Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1989 |
0.319 |
|
| 2010 |
Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron. 67: 953-66. PMID 20869593 DOI: 10.1016/J.Neuron.2010.08.044 |
0.375 |
|
| 2010 |
Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L. Erratum to Acetylation of tau inhibits its degradation and contributes to tauopathy Neuron. 68. DOI: 10.1016/J.Neuron.2010.11.013 |
0.31 |
|
| 2010 |
Gan L. Therapeutic potential and challenges of targeting sirtuins in neurodegenerative diseases Frontiers of Biology in China. 5: 324-330. DOI: 10.1007/s11515-010-0700-7 |
0.348 |
|
| 2009 |
Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, Mucke L, Gan L. Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease. Cell Stem Cell. 5: 624-33. PMID 19951690 DOI: 10.1016/J.Stem.2009.10.003 |
0.733 |
|
| 2009 |
Gan L. Sirtuin signaling in Alzheimer's disease Alzheimers & Dementia. 5: 120. DOI: 10.1016/J.Jalz.2009.05.382 |
0.355 |
|
| 2008 |
Sun B, Zhou Y, Halabisky B, Lo I, Cho SH, Mueller-Steiner S, Devidze N, Wang X, Grubb A, Gan L. Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease. Neuron. 60: 247-57. PMID 18957217 DOI: 10.1016/j.neuron.2008.10.001 |
0.41 |
|
| 2008 |
Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nature Neuroscience. 11: 1311-8. PMID 18931664 DOI: 10.1038/Nn.2213 |
0.769 |
|
| 2008 |
Gan L, Mucke L. Paths of convergence: sirtuins in aging and neurodegeneration. Neuron. 58: 10-4. PMID 18400158 DOI: 10.1016/j.neuron.2008.03.015 |
0.541 |
|
| 2008 |
Sanchez-Mejia RO, Newman JW, Toh S, Yu G, Zhou Y, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L. O4-02-03: Phospholipase A2 reduction ameliorates cognitive deficits in mouse model of Alzheimer's disease Alzheimer's & Dementia. 4: T186-T187. DOI: 10.1016/J.Jalz.2008.05.511 |
0.736 |
|
| 2008 |
Halabisky BE, Sun B, Zhou Y, Mueller-Steiner S, Wang X, Yu G, Mucke L, Gan L. P3-384: Impaired hippocampal adult neurogenesis in an animal model of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1954 |
0.569 |
|
| 2007 |
Gan L. Therapeutic potential of sirtuin-activating compounds in Alzheimer's disease. Drug News & Perspectives. 20: 233-9. PMID 17637936 DOI: 10.1358/dnp.2007.20.4.1101162 |
0.399 |
|
| 2007 |
Gan L. Therapeutic potential of amyloid β-degrading enzymes in Alzheimer's disease Future Neurology. 2: 133-137. DOI: 10.2217/14796708.2.2.133 |
0.349 |
|
| 2006 |
Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L. Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease. Neuron. 51: 703-14. PMID 16982417 DOI: 10.1016/J.Neuron.2006.07.027 |
0.615 |
|
| 2006 |
Gan L, Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Wang X, Chen J, Yu G, Esposito L, Mucke L. O4-06-05: Anti-amyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease Alzheimer's & Dementia. 2: S88-S88. DOI: 10.1016/J.Jalz.2006.05.340 |
0.565 |
|
| 2005 |
Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, Mucke L, Gan L. SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling. The Journal of Biological Chemistry. 280: 40364-74. PMID 16183991 DOI: 10.1074/Jbc.M509329200 |
0.576 |
|
| 2005 |
Kaczmarek LK, Bhattacharjee A, Desai R, Gan L, Song P, von Hehn CA, Whim MD, Yang B. Regulation of the timing of MNTB neurons by short-term and long-term modulation of potassium channels. Hearing Research. 206: 133-45. PMID 16081004 DOI: 10.1016/j.heares.2004.11.023 |
0.541 |
|
| 2004 |
Esposito L, Gan L, Yu GQ, Essrich C, Mucke L. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells. Journal of Neurochemistry. 91: 1260-74. PMID 15584903 DOI: 10.1111/j.1471-4159.2004.02816.x |
0.574 |
|
| 2004 |
Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S, Patthy L, Gonzalez-Zulueta M, Nikolich K, Urfer R. Identification of cathepsin B as a mediator of neuronal death induced by Abeta-activated microglial cells using a functional genomics approach. The Journal of Biological Chemistry. 279: 5565-72. PMID 14612454 DOI: 10.1074/Jbc.M306183200 |
0.406 |
|
| 2002 |
Bhattacharjee A, Gan L, Kaczmarek LK. Localization of the Slack potassium channel in the rat central nervous system. The Journal of Comparative Neurology. 454: 241-54. PMID 12442315 DOI: 10.1002/cne.10439 |
0.527 |
|
| 2000 |
Gan L, Yan J, Yu G, Holden K, Xu X, Mucke L. Opposing effects of the Aβ peptide and its precursor protein on the proapoptotic P53 pathway Neurobiology of Aging. 21: 184. DOI: 10.1016/S0197-4580(00)82167-3 |
0.528 |
|
| 1999 |
Gan L, Hahn SJ, Kaczmarek LK. Cell type-specific expression of the Kv3.1 gene is mediated by a negative element in the 5' untranslated region of the Kv3.1 promoter. Journal of Neurochemistry. 73: 1350-62. PMID 10501178 DOI: 10.1046/j.1471-4159.1999.0731350.x |
0.542 |
|
| 1999 |
Xu X, Yang D, Wyss-Coray T, Yan J, Gan L, Sun Y, Mucke L. Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 7547-52. PMID 10377452 DOI: 10.1073/pnas.96.13.7547 |
0.687 |
|
| 1998 |
Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK. Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits. Nature Neuroscience. 1: 462-9. PMID 10196543 DOI: 10.1038/2176 |
0.72 |
|
| 1998 |
Gan L, Kaczmarek LK. When, where, and how much? Expression of the Kv3.1 potassium channel in high-frequency firing neurons. Journal of Neurobiology. 37: 69-79. PMID 9777733 DOI: 10.1002/(SICI)1097-4695(199810)37:1<69::AID-NEU6>3.0.CO;2-6 |
0.553 |
|
| 1998 |
Wang LY, Gan L, Perney TM, Schwartz I, Kaczmarek LK. Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion. Proceedings of the National Academy of Sciences of the United States of America. 95: 1882-7. PMID 9465111 DOI: 10.1073/Pnas.95.4.1882 |
0.614 |
|
| 1996 |
Gan L, Perney TM, Kaczmarek LK. Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons. The Journal of Biological Chemistry. 271: 5859-65. PMID 8621457 DOI: 10.1074/jbc.271.10.5859 |
0.541 |
|
| 1995 |
Kanemasa T, Gan L, Perney TM, Wang LY, Kaczmarek LK. Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts. Journal of Neurophysiology. 74: 207-17. PMID 7472324 DOI: 10.1152/Jn.1995.74.1.207 |
0.622 |
|
| Show low-probability matches. |