Stanley C. Froehner - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
synapse formation, neuromuscular synapse

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kim MJ, Bible KL, Regnier M, Adams ME, Froehner SC, Whitehead NP. Simvastatin provides long-term improvement of left ventricular function and prevents cardiac fibrosis in muscular dystrophy. Physiological Reports. 7: e14018. PMID 30912308 DOI: 10.14814/phy2.14018  0.52
2019 Rao SB, Katoozi S, Skauli N, Froehner SC, Ottersen OP, Adams ME, Amiry-Moghaddam M. Targeted deletion of β1-syntrophin causes a loss of K 4.1 from Müller cell endfeet in mouse retina. Glia. PMID 30803043 DOI: 10.1002/glia.23600  0.52
2018 Kim MJ, Whitehead NP, Bible KL, Adams ME, Froehner SC. Mice lacking α-,β1- and β2-syntrophins exhibit diminished function and reduced dystrophin expression in both cardiac and skeletal muscle. Human Molecular Genetics. PMID 30256963 DOI: 10.1093/hmg/ddy341  0.52
2018 Adams ME, Odom GL, Kim MJ, Chamberlain JS, Froehner SC. Syntrophin binds directly to multiple spectrin-like repeats in dystrophin and mediates binding of nNOS to repeats 16-17. Human Molecular Genetics. PMID 29790927 DOI: 10.1093/hmg/ddy197  0.52
2016 Whitehead NP, Bible KL, Kim MJ, Odom GL, Adams ME, Froehner SC. Validation of ultrasonography for non-invasive assessment of diaphragm function in muscular dystrophy. The Journal of Physiology. PMID 27570057 DOI: 10.1113/JP272707  0.52
2016 Whitehead NP, Kim MJ, Bible KL, Adams ME, Froehner SC. Simvastatin offers new prospects for the treatment of Duchenne muscular dystrophy. Rare Diseases (Austin, Tex.). 4: e1156286. PMID 27141415 DOI: 10.1080/21675511.2016.1156286  0.52
2016 Nanou E, Yan J, Whitehead NP, Kim MJ, Froehner SC, Scheuer T, Catterall WA. Altered short-term synaptic plasticity and reduced muscle strength in mice with impaired regulation of presynaptic CaV2.1 Ca2+ channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755585 DOI: 10.1073/pnas.1524650113  0.96
2015 Rebolledo DL, Kim MJ, Whitehead NP, Adams ME, Froehner SC. Sarcolemmal targeting of nNOSμ improves contractile function of mdx muscle. Human Molecular Genetics. PMID 26604149 DOI: 10.1093/hmg/ddv466  0.52
2015 Whitehead NP, Kim MJ, Bible KL, Adams ME, Froehner SC. A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417069 DOI: 10.1073/pnas.1509536112  0.96
2015 Eisinger K, Froehner SC, Adams ME, Krautbauer S, Buechler C. Evaluation of the specificity of four commercially available antibodies to alpha-syntrophin. Analytical Biochemistry. 484: 99-101. PMID 26079703 DOI: 10.1016/j.ab.2015.06.012  0.96
2015 Hebel T, Eisinger K, Neumeier M, Rein-Fischboeck L, Pohl R, Meier EM, Boettcher A, Froehner SC, Adams ME, Liebisch G, Krautbauer S, Buechler C. Lipid abnormalities in alpha/beta2-syntrophin null mice are independent from ABCA1. Biochimica Et Biophysica Acta. 1851: 527-36. PMID 25625330 DOI: 10.1016/j.bbalip.2015.01.012  0.96
2015 Froehner SC, Reed SM, Anderson KN, Huang PL, Percival JM. Loss of nNOS inhibits compensatory muscle hypertrophy and exacerbates inflammation and eccentric contraction-induced damage in mdx mice. Human Molecular Genetics. 24: 492-505. PMID 25214536 DOI: 10.1093/hmg/ddu469  0.96
2013 Neumeier M, Krautbauer S, Schmidhofer S, Hader Y, Eisinger K, Eggenhofer E, Froehner SC, Adams ME, Mages W, Buechler C. Adiponectin receptor 1 C-terminus interacts with PDZ-domain proteins such as syntrophins. Experimental and Molecular Pathology. 95: 180-6. PMID 23860432 DOI: 10.1016/j.yexmp.2013.07.002  0.96
2013 Cruz NF, Ball KK, Froehner SC, Adams ME, Dienel GA. Regional registration of [6-(14)C]glucose metabolism during brain activation of α-syntrophin knockout mice. Journal of Neurochemistry. 125: 247-59. PMID 23346911 DOI: 10.1111/jnc.12166  0.96
2012 Fuhrmann-Stroissnigg H, Noiges R, Descovich L, Fischer I, Albrecht DE, Nothias F, Froehner SC, Propst F. The light chains of microtubule-associated proteins MAP1A and MAP1B interact with α1-syntrophin in the central and peripheral nervous system. Plos One. 7: e49722. PMID 23152929 DOI: 10.1371/journal.pone.0049722  0.96
2012 Johnson EK, Zhang L, Adams ME, Phillips A, Freitas MA, Froehner SC, Green-Church KB, Montanaro F. Proteomic analysis reveals new cardiac-specific dystrophin-associated proteins. Plos One. 7: e43515. PMID 22937058 DOI: 10.1371/journal.pone.0043515  0.96
2012 Percival JM, Whitehead NP, Adams ME, Adamo CM, Beavo JA, Froehner SC. Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy. The Journal of Pathology. 228: 77-87. PMID 22653783 DOI: 10.1002/path.4054  0.96
2012 Eilert-Olsen M, Haj-Yasein NN, Vindedal GF, Enger R, Gundersen GA, Hoddevik EH, Petersen PH, Haug FM, Skare Ø, Adams ME, Froehner SC, Burkhardt JM, Thoren AE, Nagelhus EA. Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier. Glia. 60: 432-40. PMID 22131281 DOI: 10.1002/glia.22277  0.96
2011 Martinez-Pena y Valenzuela I, Mouslim C, Pires-Oliveira M, Adams ME, Froehner SC, Akaaboune M. Nicotinic acetylcholine receptor stability at the NMJ deficient in α-syntrophin in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15586-96. PMID 22031904 DOI: 10.1523/JNEUROSCI.4038-11.2011  0.96
2011 Kim MJ, Froehner SC, Adams ME, Kim HS. α-Syntrophin is required for the hepatocyte growth factor-induced migration of cultured myoblasts. Experimental Cell Research. 317: 2914-24. PMID 22001117 DOI: 10.1016/j.yexcr.2011.09.017  0.96
2011 Percival JM, Adamo CM, Beavo JA, Froehner SC. Evaluation of the therapeutic utility of phosphodiesterase 5A inhibition in the mdx mouse model of duchenne muscular dystrophy. Handbook of Experimental Pharmacology. 323-44. PMID 21695647 DOI: 10.1007/978-3-642-17969-3_14  0.96
2010 Whitehead NP, Yeung EW, Froehner SC, Allen DG. Skeletal muscle NADPH oxidase is increased and triggers stretch-induced damage in the mdx mouse. Plos One. 5: e15354. PMID 21187957 DOI: 10.1371/journal.pone.0015354  0.96
2010 Kim MJ, Hwang SH, Lim JA, Froehner SC, Adams ME, Kim HS. Α-syntrophin modulates myogenin expression in differentiating myoblasts. Plos One. 5: e15355. PMID 21179410 DOI: 10.1371/journal.pone.0015355  0.96
2010 Adamo CM, Dai DF, Percival JM, Minami E, Willis MS, Patrucco E, Froehner SC, Beavo JA. Sildenafil reverses cardiac dysfunction in the mdx mouse model of Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 107: 19079-83. PMID 20956307 DOI: 10.1073/pnas.1013077107  0.96
2010 Schubert S, Knoch KP, Ouwendijk J, Mohammed S, Bodrov Y, Jäger M, Altkrüger A, Wegbrod C, Adams ME, Kim Y, Froehner SC, Jensen ON, Kalaidzidis Y, Solimena M. β2-Syntrophin is a Cdk5 substrate that restrains the motility of insulin secretory granules. Plos One. 5: e12929. PMID 20886068 DOI: 10.1371/journal.pone.0012929  0.96
2010 Adams ME, Anderson KN, Froehner SC. The alpha-syntrophin PH and PDZ domains scaffold acetylcholine receptors, utrophin, and neuronal nitric oxide synthase at the neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11004-10. PMID 20720107 DOI: 10.1523/JNEUROSCI.1930-10.2010  0.96
2010 Bragg AD, Das SS, Froehner SC. Dystrophin-associated protein scaffolding in brain requires alpha-dystrobrevin. Neuroreport. 21: 695-9. PMID 20508543 DOI: 10.1097/WNR.0b013e32833b0a3b  0.96
2010 Migliati ER, Amiry-Moghaddam M, Froehner SC, Adams ME, Ottersen OP, Bhardwaj A. Na(+)-K (+)-2Cl (-) cotransport inhibitor attenuates cerebral edema following experimental stroke via the perivascular pool of aquaporin-4. Neurocritical Care. 13: 123-31. PMID 20458553 DOI: 10.1007/s12028-010-9376-8  0.96
2010 Percival JM, Anderson KN, Huang P, Adams ME, Froehner SC. Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle. The Journal of Clinical Investigation. 120: 816-26. PMID 20124730 DOI: 10.1172/JCI40736  0.96
2009 Banks GB, Chamberlain JS, Froehner SC. Truncated dystrophins can influence neuromuscular synapse structure. Molecular and Cellular Neurosciences. 40: 433-41. PMID 19171194 DOI: 10.1016/j.mcn.2008.12.011  0.96
2009 Steen MS, Adams ME, Tesch Y, Froehner SC. Amelioration of muscular dystrophy by transgenic expression of Niemann-Pick C1. Molecular Biology of the Cell. 20: 146-52. PMID 18946078 DOI: 10.1091/mbc.E08-08-0811  0.96
2008 Compton AG, Albrecht DE, Seto JT, Cooper ST, Ilkovski B, Jones KJ, Challis D, Mowat D, Ranscht B, Bahlo M, Froehner SC, North KN. Mutations in contactin-1, a neural adhesion and neuromuscular junction protein, cause a familial form of lethal congenital myopathy. American Journal of Human Genetics. 83: 714-24. PMID 19026398 DOI: 10.1016/j.ajhg.2008.10.022  0.96
2008 Percival JM, Anderson KN, Gregorevic P, Chamberlain JS, Froehner SC. Functional deficits in nNOSmu-deficient skeletal muscle: myopathy in nNOS knockout mice. Plos One. 3: e3387. PMID 18852886 DOI: 10.1371/journal.pone.0003387  0.96
2008 Zeynalov E, Chen CH, Froehner SC, Adams ME, Ottersen OP, Amiry-Moghaddam M, Bhardwaj A. The perivascular pool of aquaporin-4 mediates the effect of osmotherapy in postischemic cerebral edema. Critical Care Medicine. 36: 2634-40. PMID 18679106 DOI: 10.1097/CCM.0b013e3181847853  0.96
2008 Liu X, Zhang W, Alkayed NJ, Froehner SC, Adams ME, Amiry-Moghaddam M, Ottersen OP, Hurn PD, Bhardwaj A. Lack of sex-linked differences in cerebral edema and aquaporin-4 expression after experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1898-906. PMID 18648381 DOI: 10.1038/jcbfm.2008.83  0.96
2008 Albrecht DE, Sherman DL, Brophy PJ, Froehner SC. The ABCA1 cholesterol transporter associates with one of two distinct dystrophin-based scaffolds in Schwann cells. Glia. 56: 611-8. PMID 18286648 DOI: 10.1002/glia.20636  0.96
2008 Adams ME, Tesch Y, Percival JM, Albrecht DE, Conhaim JI, Anderson K, Froehner SC. Differential targeting of nNOS and AQP4 to dystrophin-deficient sarcolemma by membrane-directed alpha-dystrobrevin. Journal of Cell Science. 121: 48-54. PMID 18057022 DOI: 10.1242/jcs.020701  0.96
2007 Wang D, Kelly BB, Albrecht DE, Adams ME, Froehner SC, Feng G. Complete deletion of all alpha-dystrobrevin isoforms does not reveal new neuromuscular junction phenotype. Gene Expression. 14: 47-57. PMID 17933218 DOI: 10.3727/000000007783991745  0.96
2007 Percival JM, Gregorevic P, Odom GL, Banks GB, Chamberlain JS, Froehner SC. rAAV6-microdystrophin rescues aberrant Golgi complex organization in mdx skeletal muscles. Traffic (Copenhagen, Denmark). 8: 1424-39. PMID 17714427 DOI: 10.1111/j.1600-0854.2007.00622.x  0.96
2007 Percival JM, Froehner SC. Golgi complex organization in skeletal muscle: a role for Golgi-mediated glycosylation in muscular dystrophies? Traffic (Copenhagen, Denmark). 8: 184-94. PMID 17319799 DOI: 10.1111/j.1600-0854.2006.00523.x  0.96
2006 Alessi A, Bragg AD, Percival JM, Yoo J, Albrecht DE, Froehner SC, Adams ME. gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins. Experimental Cell Research. 312: 3084-95. PMID 16857187 DOI: 10.1016/j.yexcr.2006.06.019  0.96
2006 Gregorevic P, Allen JM, Minami E, Blankinship MJ, Haraguchi M, Meuse L, Finn E, Adams ME, Froehner SC, Murry CE, Chamberlain JS. rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice. Nature Medicine. 12: 787-9. PMID 16819550 DOI: 10.1038/nm1439  0.96
2006 Mercado ML, Amenta AR, Hagiwara H, Rafii MS, Lechner BE, Owens RT, McQuillan DJ, Froehner SC, Fallon JR. Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1724-6. PMID 16807372 DOI: 10.1096/fj.05-5124fje  0.96
2006 Bragg AD, Amiry-Moghaddam M, Ottersen OP, Adams ME, Froehner SC. Assembly of a perivascular astrocyte protein scaffold at the mammalian blood-brain barrier is dependent on alpha-syntrophin. Glia. 53: 879-90. PMID 16609960 DOI: 10.1002/glia.20347  0.96
2006 Puwarawuttipanit W, Bragg AD, Frydenlund DS, Mylonakou MN, Nagelhus EA, Peters MF, Kotchabhakdi N, Adams ME, Froehner SC, Haug FM, Ottersen OP, Amiry-Moghaddam M. Differential effect of alpha-syntrophin knockout on aquaporin-4 and Kir4.1 expression in retinal macroglial cells in mice. Neuroscience. 137: 165-75. PMID 16257493 DOI: 10.1016/j.neuroscience.2005.08.051  0.96
2005 Yan J, Wen W, Xu W, Long JF, Adams ME, Froehner SC, Zhang M. Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin. The Embo Journal. 24: 3985-95. PMID 16252003 DOI: 10.1038/sj.emboj.7600858  0.96
2005 Luo S, Chen Y, Lai KO, Arévalo JC, Froehner SC, Adams ME, Chao MV, Ip NY. {alpha}-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner. The Journal of Cell Biology. 169: 813-24. PMID 15939763 DOI: 10.1083/jcb.200412008  0.96
2005 Compton AG, Cooper ST, Hill PM, Yang N, Froehner SC, North KN. The syntrophin-dystrobrevin subcomplex in human neuromuscular disorders. Journal of Neuropathology and Experimental Neurology. 64: 350-61. PMID 15835271  0.96
2004 Adams ME, Kramarcy N, Fukuda T, Engel AG, Sealock R, Froehner SC. Structural abnormalities at neuromuscular synapses lacking multiple syntrophin isoforms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10302-9. PMID 15548643 DOI: 10.1523/JNEUROSCI.3408-04.2004  0.96
2004 Shiao T, Fond A, Deng B, Wehling-Henricks M, Adams ME, Froehner SC, Tidball JG. Defects in neuromuscular junction structure in dystrophic muscle are corrected by expression of a NOS transgene in dystrophin-deficient muscles, but not in muscles lacking alpha- and beta1-syntrophins. Human Molecular Genetics. 13: 1873-84. PMID 15238508 DOI: 10.1093/hmg/ddh204  0.96
2004 Connors NC, Adams ME, Froehner SC, Kofuji P. The potassium channel Kir4.1 associates with the dystrophin-glycoprotein complex via alpha-syntrophin in glia. The Journal of Biological Chemistry. 279: 28387-92. PMID 15102837 DOI: 10.1074/jbc.M402604200  0.96
2004 Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR, Vandenberg CA. Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. The Journal of Biological Chemistry. 279: 22331-46. PMID 15024025 DOI: 10.1074/jbc.M400285200  0.96
2004 Amiry-Moghaddam M, Xue R, Haug FM, Neely JD, Bhardwaj A, Agre P, Adams ME, Froehner SC, Mori S, Ottersen OP. Alpha-syntrophin deletion removes the perivascular but not endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 542-4. PMID 14734638 DOI: 10.1096/fj.03-0869fje  0.96
2004 Albrecht DE, Froehner SC. DAMAGE, a novel alpha-dystrobrevin-associated MAGE protein in dystrophin complexes. The Journal of Biological Chemistry. 279: 7014-23. PMID 14623885 DOI: 10.1074/jbc.M312205200  0.96
2003 Banks GB, Fuhrer C, Adams ME, Froehner SC. The postsynaptic submembrane machinery at the neuromuscular junction: requirement for rapsyn and the utrophin/dystrophin-associated complex. Journal of Neurocytology. 32: 709-26. PMID 15034263 DOI: 10.1023/B:NEUR.0000020619.24681.2b  0.96
2003 Amiry-Moghaddam M, Williamson A, Palomba M, Eid T, de Lanerolle NC, Nagelhus EA, Adams ME, Froehner SC, Agre P, Ottersen OP. Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of alpha-syntrophin-null mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 13615-20. PMID 14597704 DOI: 10.1073/pnas.2336064100  0.96
2003 Jones KJ, Compton AG, Yang N, Mills MA, Peters MF, Mowat D, Kunkel LM, Froehner SC, North KN. Deficiency of the syntrophins and alpha-dystrobrevin in patients with inherited myopathy. Neuromuscular Disorders : Nmd. 13: 456-67. PMID 12899872 DOI: 10.1016/S0960-8966(03)00066-X  0.96
2003 Steen MS, Froehner SC. PerleCan fix your muscle AChEs. Trends in Neurosciences. 26: 241-2. PMID 12744839 DOI: 10.1016/S0166-2236(03)00077-8  0.96
2003 Thomas GD, Shaul PW, Yuhanna IS, Froehner SC, Adams ME. Vasomodulation by skeletal muscle-derived nitric oxide requires alpha-syntrophin-mediated sarcolemmal localization of neuronal Nitric oxide synthase. Circulation Research. 92: 554-60. PMID 12600881 DOI: 10.1161/01.RES.0000061570.83105.52  0.96
2003 Amiry-Moghaddam M, Otsuka T, Hurn PD, Traystman RJ, Haug FM, Froehner SC, Adams ME, Neely JD, Agre P, Ottersen OP, Bhardwaj A. An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proceedings of the National Academy of Sciences of the United States of America. 100: 2106-11. PMID 12578959 DOI: 10.1073/pnas.0437946100  0.96
2002 Albrecht DE, Froehner SC. Syntrophins and dystrobrevins: defining the dystrophin scaffold at synapses. Neuro-Signals. 11: 123-9. PMID 12138249 DOI: 10.1159/000065053  0.96
2002 Froehner SC. Just say NO to muscle degeneration? Trends in Molecular Medicine. 8: 51-3. PMID 11815264 DOI: 10.1016/S1471-4914(02)02275-X  0.96
2002 Phillips WD, Froehner SC. GABARAP and GABA(A) receptor clustering. Neuron. 33: 4-6. PMID 11779472 DOI: 10.1016/S0896-6273(01)00569-4  0.96
2001 Neely JD, Amiry-Moghaddam M, Ottersen OP, Froehner SC, Agre P, Adams ME. Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 14108-13. PMID 11717465 DOI: 10.1073/pnas.241508198  0.96
2001 Adams ME, Mueller HA, Froehner SC. In vivo requirement of the alpha-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4. The Journal of Cell Biology. 155: 113-22. PMID 11571312 DOI: 10.1083/jcb.200106158  0.96
2001 Ort T, Voronov S, Guo J, Zawalich K, Froehner SC, Zawalich W, Solimena M. Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion. The Embo Journal. 20: 4013-23. PMID 11483505 DOI: 10.1093/emboj/20.15.4013  0.96
2000 Ort T, Maksimova E, Dirkx R, Kachinsky AM, Berghs S, Froehner SC, Solimena M. The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells. European Journal of Cell Biology. 79: 621-30. PMID 11043403  0.96
2000 Crawford GE, Faulkner JA, Crosbie RH, Campbell KP, Froehner SC, Chamberlain JS. Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain. The Journal of Cell Biology. 150: 1399-410. PMID 10995444 DOI: 10.1083/jcb.150.6.1399  0.96
2000 Adams ME, Kramarcy N, Krall SP, Rossi SG, Rotundo RL, Sealock R, Froehner SC. Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin. The Journal of Cell Biology. 150: 1385-98. PMID 10995443 DOI: 10.1083/jcb.150.6.1385  0.96
2000 Rocco P, Vainzof M, Froehner SC, Peters MF, Marie SK, Passos-Bueno MR, Zatz M. Brazilian family with pure autosomal dominant spastic paraplegia maps to 8q: analysis of muscle beta 1 syntrophin. American Journal of Medical Genetics. 92: 122-7. PMID 10797436 DOI: 10.1002/(SICI)1096-8628(20000515)92:2<122::AID-AJMG8>3.0.CO;2-B  0.96
1999 Won S, Si J, Colledge M, Ravichandran KS, Froehner SC, Mei L. Neuregulin-increased expression of acetylcholine receptor epsilon-subunit gene requires ErbB interaction with Shc. Journal of Neurochemistry. 73: 2358-68. PMID 10582594 DOI: 10.1046/j.1471-4159.1999.0732358.x  0.96
1999 Kachinsky AM, Froehner SC, Milgram SL. A PDZ-containing scaffold related to the dystrophin complex at the basolateral membrane of epithelial cells. The Journal of Cell Biology. 145: 391-402. PMID 10209032 DOI: 10.1083/jcb.145.2.391  0.96
1998 Froehner SC. Gathering glycine receptors at synapses. Science (New York, N.Y.). 282: 1277-9. PMID 9867632  0.96
1998 Peters MF, Sadoulet-Puccio HM, Grady MR, Kramarcy NR, Kunkel LM, Sanes JR, Sealock R, Froehner SC. Differential membrane localization and intermolecular associations of alpha-dystrobrevin isoforms in skeletal muscle. The Journal of Cell Biology. 142: 1269-78. PMID 9732287 DOI: 10.1083/jcb.142.5.1269  0.96
1998 Gee SH, Sekely SA, Lombardo C, Kurakin A, Froehner SC, Kay BK. Cyclic peptides as non-carboxyl-terminal ligands of syntrophin PDZ domains. The Journal of Biological Chemistry. 273: 21980-7. PMID 9705339 DOI: 10.1074/jbc.273.34.21980  0.96
1998 Colledge M, Froehner SC. Signals mediating ion channel clustering at the neuromuscular junction. Current Opinion in Neurobiology. 8: 357-63. PMID 9687350 DOI: 10.1016/S0959-4388(98)80061-5  0.96
1998 Colledge M, Froehner SC. Interaction between the nicotinic acetylcholine receptor and Grb2. Implications for signaling at the neuromuscular junction. Annals of the New York Academy of Sciences. 841: 17-27. PMID 9668219 DOI: 10.1111/j.1749-6632.1998.tb10907.x  0.96
1998 Colledge M, Froehner SC. To muster a cluster: anchoring neurotransmitter receptors at synapses. Proceedings of the National Academy of Sciences of the United States of America. 95: 3341-3. PMID 9520364 DOI: 10.1073/pnas.95.7.3341  0.96
1998 Montanaro F, Gee SH, Jacobson C, Lindenbaum MH, Froehner SC, Carbonetto S. Laminin and alpha-dystroglycan mediate acetylcholine receptor aggregation via a MuSK-independent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1250-60. PMID 9454835  0.96
1998 Gee SH, Madhavan R, Levinson SR, Caldwell JH, Sealock R, Froehner SC. Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 128-37. PMID 9412493  0.96
1997 Peters MF, O'Brien KF, Sadoulet-Puccio HM, Kunkel LM, Adams ME, Froehner SC. beta-dystrobrevin, a new member of the dystrophin family. Identification, cloning, and protein associations. The Journal of Biological Chemistry. 272: 31561-9. PMID 9395493 DOI: 10.1074/jbc.272.50.31561  0.96
1997 Peters MF, Adams ME, Froehner SC. Differential association of syntrophin pairs with the dystrophin complex. The Journal of Cell Biology. 138: 81-93. PMID 9214383 DOI: 10.1083/jcb.138.1.81  0.96
1997 Froehner SC, Adams ME, Peters MF, Gee SH. Syntrophins: modular adapter proteins at the neuromuscular junction and the sarcolemma. Society of General Physiologists Series. 52: 197-207. PMID 9210230  0.96
1997 Colledge M, Froehner SC. Tyrosine phosphorylation of nicotinic acetylcholine receptor mediates Grb2 binding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5038-45. PMID 9185541  0.96
1996 Chao DS, Gorospe JR, Brenman JE, Rafael JA, Peters MF, Froehner SC, Hoffman EP, Chamberlain JS, Bredt DS. Selective loss of sarcolemmal nitric oxide synthase in Becker muscular dystrophy. The Journal of Experimental Medicine. 184: 609-18. PMID 8760814  0.96
1996 Dai Z, Scotland PB, Froehner SC, Peng HB. Association of phosphotyrosine with rapsyn expression in Xenopus embryonic cells. Neuroreport. 7: 657-61. PMID 8730851  0.96
1996 Blake DJ, Nawrotzki R, Peters MF, Froehner SC, Davies KE. Isoform diversity of dystrobrevin, the murine 87-kDa postsynaptic protein. The Journal of Biological Chemistry. 271: 7802-10. PMID 8631824 DOI: 10.1074/jbc.271.13.7802  0.96
1996 Brenman JE, Chao DS, Gee SH, McGee AW, Craven SE, Santillano DR, Wu Z, Huang F, Xia H, Peters MF, Froehner SC, Bredt DS. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Cell. 84: 757-67. PMID 8625413 DOI: 10.1016/S0092-8674(00)81053-3  0.96
1995 Barry EL, Viglione MP, Kim YI, Froehner SC. Expression and antibody inhibition of P-type calcium channels in human small-cell lung carcinoma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 274-83. PMID 7823133  0.96
1995 Froehner SC, Fallon JR. Neurobiology. Synapses take the rap. Nature. 377: 195-6. PMID 7675104 DOI: 10.1038/377195a0  0.96
1995 Adams ME, Dwyer TM, Dowler LL, White RA, Froehner SC. Mouse alpha 1- and beta 2-syntrophin gene structure, chromosome localization, and homology with a discs large domain. The Journal of Biological Chemistry. 270: 25859-65. PMID 7592771 DOI: 10.1074/jbc.270.43.25859  0.96
1995 Dwyer TM, Froehner SC. Direct binding of Torpedo syntrophin to dystrophin and the 87 kDa dystrophin homologue. Febs Letters. 375: 91-4. PMID 7498489 DOI: 10.1016/0014-5793(95)01176-F  0.96
1995 Barry EL, Gesek FA, Froehner SC, Friedman PA. Multiple calcium channel transcripts in rat osteosarcoma cells: selective activation of alpha 1D isoform by parathyroid hormone. Proceedings of the National Academy of Sciences of the United States of America. 92: 10914-8. PMID 7479909  0.96
1994 Kramarcy NR, Vidal A, Froehner SC, Sealock R. Association of utrophin and multiple dystrophin short forms with the mammalian M(r) 58,000 dystrophin-associated protein (syntrophin). The Journal of Biological Chemistry. 269: 2870-6. PMID 8300622  0.96
1994 Sealock R, Froehner SC. Dystrophin-associated proteins and synapse formation: is alpha-dystroglycan the agrin receptor? Cell. 77: 617-9. PMID 8205610 DOI: 10.1016/0092-8674(94)90045-0  0.96
1994 Bloch RJ, Sealock R, Pumplin DW, Luther PW, Froehner SC. Association of acetylcholine receptors with peripheral membrane proteins: evidence from antibody-induced coaggregation. The Journal of Membrane Biology. 138: 13-28. PMID 8189428 DOI: 10.1007/BF00211065  0.96
1994 Morton ME, Cassidy TN, Froehner SC, Gilmour BP, Laurens RL. Alpha 1 and alpha 2 Ca2+ channel subunit expression in human neuronal and small cell carcinoma cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 8: 884-8. PMID 8070639  0.96
1994 Ousley AH, Froehner SC. An anti-peptide antibody specific for the class A calcium channel alpha 1 subunit labels mammalian neuromuscular junction. Proceedings of the National Academy of Sciences of the United States of America. 91: 12263-7. PMID 7991616  0.96
1994 Peters MF, Kramarcy NR, Sealock R, Froehner SC. beta 2-Syntrophin: localization at the neuromuscular junction in skeletal muscle. Neuroreport. 5: 1577-80. PMID 7819523  0.96
1993 Froehner SC. Neurobiology. Anchoring glycine receptors. Nature. 366: 719. PMID 8264792 DOI: 10.1038/366719a0  0.96
1993 Scotland PB, Colledge M, Melnikova I, Dai Z, Froehner SC. Clustering of the acetylcholine receptor by the 43-kD protein: involvement of the zinc finger domain. The Journal of Cell Biology. 123: 719-28. PMID 8227134  0.96
1993 Adams ME, Butler MH, Dwyer TM, Peters MF, Murnane AA, Froehner SC. Two forms of mouse syntrophin, a 58 kd dystrophin-associated protein, differ in primary structure and tissue distribution. Neuron. 11: 531-40. PMID 7691103 DOI: 10.1016/0896-6273(93)90157-M  0.96
1993 Froehner SC. Regulation of ion channel distribution at synapses. Annual Review of Neuroscience. 16: 347-68. PMID 7681636 DOI: 10.1146/annurev.ne.16.030193.002023  0.96
1993 Froehner SC. Anchoring glycine receptors Nature. 366: 719.  0.96
1992 Butler MH, Douville K, Murnane AA, Kramarcy NR, Cohen JB, Sealock R, Froehner SC. Association of the Mr 58,000 postsynaptic protein of electric tissue with Torpedo dystrophin and the Mr 87,000 postsynaptic protein. The Journal of Biological Chemistry. 267: 6213-8. PMID 1556129  0.96
1992 Brennan C, Scotland PB, Froehner SC, Henderson LP. Functional properties of acetylcholine receptors coexpressed with the 43K protein in heterologous cell systems. Developmental Biology. 149: 100-11. PMID 1370223 DOI: 10.1016/0012-1606(92)90267-K  0.96
1991 Froehner SC. The submembrane machinery for nicotinic acetylcholine receptor clustering. The Journal of Cell Biology. 114: 1-7. PMID 2050736  0.96
1991 Sealock R, Butler MH, Kramarcy NR, Gao KX, Murnane AA, Douville K, Froehner SC. Localization of dystrophin relative to acetylcholine receptor domains in electric tissue and adult and cultured skeletal muscle. The Journal of Cell Biology. 113: 1133-44. PMID 2040646  0.96
1991 Hamilton SL, Codina J, Hawkes MJ, Yatani A, Sawada T, Strickland FM, Froehner SC, Spiegel AM, Toro L, Stefani E. Evidence for direct interaction of Gs alpha with the Ca2+ channel of skeletal muscle. The Journal of Biological Chemistry. 266: 19528-35. PMID 1655789  0.96
1990 LaRochelle WJ, Witzemann V, Fiedler W, Froehner SC. Developmental expression of the 43K and 58K postsynaptic membrane proteins and nicotinic acetylcholine receptors in Torpedo electrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3460-7. PMID 2213148  0.96
1990 Flucher BE, Morton ME, Froehner SC, Daniels MP. Localization of the alpha 1 and alpha 2 subunits of the dihydropyridine receptor and ankyrin in skeletal muscle triads. Neuron. 5: 339-51. PMID 2169270 DOI: 10.1016/0896-6273(90)90170-K  0.96
1990 Froehner SC, Luetje CW, Scotland PB, Patrick J. The postsynaptic 43K protein clusters muscle nicotinic acetylcholine receptors in Xenopus oocytes. Neuron. 5: 403-10. PMID 1698395 DOI: 10.1016/0896-6273(90)90079-U  0.96
1990 LaRochelle WJ, Froehner SC. Staining of proteins on nitrocellulose replicas. Methods in Enzymology. 184: 433-6. PMID 1697024 DOI: 10.1016/0076-6879(90)84305-Z  0.96
1990 Larochelle WJ, Froehner SC. [50] Staining of proteins on nitrocellulose replicas Methods in Enzymology. 184: 430-433. DOI: 10.1016/0076-6879(90)84304-Y  0.96
1989 Sealock R, Murnane AA, Paulin D, Froehner SC. Immunochemical identification of desmin in Torpedo postsynaptic membranes and at the rat neuromuscular junction. Synapse (New York, N.Y.). 3: 315-24. PMID 2740991 DOI: 10.1002/syn.890030404  0.96
1989 Froehner SC. Expression of RNA transcripts for the postsynaptic 43 kDa protein in innervated and denervated rat skeletal muscle. Febs Letters. 249: 229-33. PMID 2737281 DOI: 10.1016/0014-5793(89)80629-5  0.96
1989 LaRochelle WJ, Ralston E, Forsayeth JR, Froehner SC, Hall ZW. Clusters of 43-kDa protein are absent from genetic variants of C2 muscle cells with reduced acetylcholine receptor expression. Developmental Biology. 132: 130-8. PMID 2645181 DOI: 10.1016/0012-1606(89)90211-X  0.96
1989 Froehner SC. Macromolecular organization of the neuromuscular postsynaptic membrane. Annals of the New York Academy of Sciences. 568: 115-20. PMID 2629580 DOI: 10.1111/j.1749-6632.1989.tb12497.x  0.96
1989 Morton ME, Froehner SC. The alpha 1 and alpha 2 polypeptides of the dihydropyridine-sensitive calcium channel differ in developmental expression and tissue distribution. Neuron. 2: 1499-506. PMID 2560646 DOI: 10.1016/0896-6273(89)90196-7  0.96
1988 Froehner SC, Davies A, Baldwin SA, Lienhard GE. The blood-nerve barrier is rich in glucose transporter. Journal of Neurocytology. 17: 173-8. PMID 3060567 DOI: 10.1007/BF01674204  0.96
1988 Froehner SC. New insights into the molecular structure of the dihydropyridine-sensitive calcium channel. Trends in Neurosciences. 11: 90-2. PMID 2465612 DOI: 10.1016/0166-2236(88)90149-X  0.96
1988 Morton ME, Caffrey JM, Brown AM, Froehner SC. Monoclonal antibody to the alpha 1-subunit of the dihydropyridine-binding complex inhibits calcium currents in BC3H1 myocytes. The Journal of Biological Chemistry. 263: 613-6. PMID 2447079  0.96
1987 LaRochelle WJ, Froehner SC. Comparison of the postsynaptic 43-kDa protein from muscle cells that differ in acetylcholine receptor clustering activity. The Journal of Biological Chemistry. 262: 8190-5. PMID 3597369  0.96
1987 Bloch RJ, Froehner SC. The relationship of the postsynaptic 43K protein to acetylcholine receptors in receptor clusters isolated from cultured rat myotubes. The Journal of Cell Biology. 104: 645-54. PMID 3546336  0.96
1987 Froehner SC, Murnane AA, Tobler M, Peng HB, Sealock R. A postsynaptic Mr 58,000 (58K) protein concentrated at acetylcholine receptor-rich sites in Torpedo electroplaques and skeletal muscle. The Journal of Cell Biology. 104: 1633-46. PMID 3294859  0.96
1987 Morton ME, Froehner SC. Monoclonal antibody identifies a 200-kDa subunit of the dihydropyridine-sensitive calcium channel. The Journal of Biological Chemistry. 262: 11904-7. PMID 2442152  0.96
1986 LaRochelle WJ, Froehner SC. Immunochemical detection of proteins biotinylated on nitrocellulose replicas. Journal of Immunological Methods. 92: 65-71. PMID 3528300 DOI: 10.1016/0022-1759(86)90504-1  0.96
1986 LaRochelle WJ, Froehner SC. Determination of the tissue distributions and relative concentrations of the postsynaptic 43-kDa protein and the acetylcholine receptor in Torpedo. The Journal of Biological Chemistry. 261: 5270-4. PMID 3514614  0.96
1986 Froehner SC. The role of the postsynaptic cytoskeleton in AChR organization Trends in Neurosciences. 9: 37-41. DOI: 10.1016/0166-2236(86)90013-5  0.96
1985 Porter S, Froehner SC. Interaction of the 43K protein with components of Torpedo postsynaptic membranes. Biochemistry. 24: 425-32. PMID 3978083  0.96
1985 LaRochelle WJ, Wray BE, Sealock R, Froehner SC. Immunochemical demonstration that amino acids 360-377 of the acetylcholine receptor gamma-subunit are cytoplasmic. The Journal of Cell Biology. 100: 684-91. PMID 3972889  0.96
1985 Peng HB, Froehner SC. Association of the postsynaptic 43K protein with newly formed acetylcholine receptor clusters in cultured muscle cells. The Journal of Cell Biology. 100: 1698-705. PMID 3886673  0.96
1984 Sealock R, Wray BE, Froehner SC. Ultrastructural localization of the Mr 43,000 protein and the acetylcholine receptor in Torpedo postsynaptic membranes using monoclonal antibodies. The Journal of Cell Biology. 98: 2239-44. PMID 6725413  0.96
1984 Froehner SC. Peripheral proteins of postsynaptic membranes from Torpedo electric organ identified with monoclonal antibodies. The Journal of Cell Biology. 99: 88-96. PMID 6376523  0.96
1983 Porter S, Froehner SC. Characterization and localization of the Mr = 43,000 proteins associated with acetylcholine receptor-rich membranes. The Journal of Biological Chemistry. 258: 10034-40. PMID 6885756  0.96
1983 Hyman C, Froehner SC. Degradation of acetylcholine receptors in muscle cells: effect of leupeptin on turnover rate, intracellular pool sizes, and receptor properties. The Journal of Cell Biology. 96: 1316-24. PMID 6841450  0.96
1983 Froehner SC, Douville K, Klink S, Culp WJ. Monoclonal antibodies to cytoplasmic domains of the acetylcholine receptor. The Journal of Biological Chemistry. 258: 7112-20. PMID 6189834  0.96
1982 St John PA, Froehner SC, Goodenough DA, Cohen JB. Nicotinic postsynaptic membranes from Torpedo: sidedness, permeability to macromolecules, and topography of major polypeptides. The Journal of Cell Biology. 92: 333-42. PMID 6174528  0.96
1981 Haggerty JG, Froehner SC. Restoration of 125I-alpha-bungarotoxin binding activity to the alpha subunit of Torpedo acetylcholine receptor isolated by gel electrophoresis in sodium dodecyl sulfate. The Journal of Biological Chemistry. 256: 8294-7. PMID 7263653  0.96
1981 Froehner SC, Gulbrandsen V, Hyman C, Jeng AY, Neubig RR, Cohen JB. Immunofluorescence localization at the mammalian neuromuscular junction of the Mr 43,000 protein of Torpedo postsynaptic membranes. Proceedings of the National Academy of Sciences of the United States of America. 78: 5230-4. PMID 7029531  0.96
1981 Froehner SC. Identification of exposed and buried determinants of the membrane-bound acetylcholine receptor from Torpedo californica. Biochemistry. 20: 4905-15. PMID 6170319  0.96
1979 Froehner SC, Rafto S. Comparison of the subunits of Torpedo californica acetylcholine receptor by peptide mapping. Biochemistry. 18: 301-7. PMID 420786  0.96
1977 Froehner SC, Reiness CG, Hall ZW. Subunit structure of the acetylcholine receptor from denervated rat skeletal muscle. The Journal of Biological Chemistry. 252: 8589-96. PMID 925013  0.96
1977 Froehner SC, Karlin A, Hall ZW. Affinity alkylation labels two subunits of the reduced acetylcholine receptor from mammalian muscle. Proceedings of the National Academy of Sciences of the United States of America. 74: 4685-8. PMID 270707  0.96
1975 Froehner SC, Eriksson K. Properties of the glycoprotein laccase immobilized by two methods. Acta Chemica Scandinavica. Series B: Organic Chemistry and Biochemistry. 29: 691. PMID 242172  0.96
1974 Froehner SC, Eriksson KE. Purification and properties of Neurospora crassa laccase. Journal of Bacteriology. 120: 458-65. PMID 4278681  0.96
1974 Froehner SC, Eriksson KE. Induction of Neurospora crassa laccase with protein synthesis inhibitors. Journal of Bacteriology. 120: 450-7. PMID 4278535  0.96
1973 Froehner SC, Bonner J. Ascites tumor ribonucleic acid polymerases. Isolation, purification, and factor stimulation. Biochemistry. 12: 3064-71. PMID 4354251  0.96
1970 Horowitz NH, Fling M, Feldman HM, Pall ML, Froehner SC. Derepression of tyrosinase synthesis in Neurospora by amino acid analogs. Developmental Biology. 21: 147-56. PMID 4986502 DOI: 10.1016/0012-1606(70)90066-7  0.96
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