Stephanie Cragg - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Simpson EH, Akam T, Patriarchi T, Blanco-Pozo M, Burgeno LM, Mohebi A, Cragg SJ, Walton ME. Lights, fiber, action! A primer on in vivo fiber photometry. Neuron. PMID 38103545 DOI: 10.1016/j.neuron.2023.11.016  0.754
2023 Brimblecombe KR, Connor-Robson N, Bataille CJR, Roberts BM, Gracie C, O'Connor B, Te Water Naude R, Karthik G, Russell AJ, Wade-Martins R, Cragg SJ. Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's. The European Journal of Neuroscience. PMID 37941514 DOI: 10.1111/ejn.16180  0.872
2023 Caldwell M, Ayo-Jibunoh V, Mendoza JC, Brimblecombe KR, Reynolds LM, Zhu Jiang XY, Alarcon C, Fiore E, N Tomaio J, Phillips GR, Mingote S, Flores C, Casaccia P, Liu J, Cragg SJ, et al. Axo-glial interactions between midbrain dopamine neurons and oligodendrocyte lineage cells in the anterior corpus callosum. Brain Structure & Function. PMID 37668732 DOI: 10.1007/s00429-023-02695-y  0.831
2023 Christie LA, Brice NL, Rowland A, Dickson L, Anand R, Teall M, Doyle KJ, Narayana L, Mitchell C, Harvey JRM, Mulligan V, Dawson LA, Cragg SJ, Carlton M, Bürli RW. Discovery of , a Novel Brain-Penetrant α6-Containing Nicotinic Receptor Antagonist for the Modulation of Motor Dysfunction. Journal of Medicinal Chemistry. PMID 37651656 DOI: 10.1021/acs.jmedchem.3c00630  0.514
2023 Cramb KML, Beccano-Kelly D, Cragg SJ, Wade-Martins R. Impaired dopamine release in Parkinson's disease. Brain : a Journal of Neurology. PMID 36864664 DOI: 10.1093/brain/awad064  0.552
2022 Kosillo P, Ahmed KM, Aisenberg EE, Karalis V, Roberts BM, Cragg SJ, Bateup HS. Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2. Elife. 11. PMID 35881440 DOI: 10.7554/eLife.75398  0.867
2022 Roberts BM, Lambert E, Livesey JA, Wu Z, Li Y, Cragg SJ. Dopamine release in nucleus accumbens is under tonic inhibition by adenosine A receptors regulated by astrocytic ENT1 and dysregulated by ethanol. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35042768 DOI: 10.1523/JNEUROSCI.1548-21.2021  0.785
2021 Threlfell S, Mohammadi AS, Ryan BJ, Connor-Robson N, Platt NJ, Anand R, Serres F, Sharp T, Bengoa-Vergniory N, Wade-Martins R, Ewing A, Cragg SJ, Brimblecombe KR. Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol. Frontiers in Cellular Neuroscience. 15: 658244. PMID 33935654 DOI: 10.3389/fncel.2021.658244  0.831
2021 Zhang YF, Cragg SJ. Revisiting dopamine-acetylcholine imbalance in Parkinson's disease: Glutamate co-transmission as an exciting partner in crime. Neuron. 109: 1070-1071. PMID 33831360 DOI: 10.1016/j.neuron.2021.03.018  0.621
2021 Roberts BM, Lopes EF, Cragg SJ. Axonal Modulation of Striatal Dopamine Release by Local γ-Aminobutyric Acid (GABA) Signalling. Cells. 10. PMID 33806845 DOI: 10.3390/cells10030709  0.84
2020 Roberts BM, Doig NM, Brimblecombe KR, Lopes EF, Siddorn RE, Threlfell S, Connor-Robson N, Bengoa-Vergniory N, Pasternack N, Wade-Martins R, Magill PJ, Cragg SJ. GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model. Nature Communications. 11: 4958. PMID 33009395 DOI: 10.1038/s41467-020-18247-5  0.84
2020 Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, ... Cragg S, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nature Communications. 11: 4885. PMID 32985503 DOI: 10.1038/s41467-020-18689-x  0.794
2019 Hunn BHM, Vingill S, Threlfell S, Alegre-Abarrategui J, Magdelyns M, Deltheil T, Bengoa-Vergniory N, Oliver PL, Cioroch M, Doig NM, Bannerman DM, Cragg SJ, Wade-Martins R. Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior. Cell Reports. 29: 920-931.e7. PMID 31644913 DOI: 10.1016/J.Celrep.2019.09.029  0.856
2019 Condon MD, Platt NJ, Zhang YF, Roberts BM, Clements MA, Vietti-Michelina S, Tseu MY, Brimblecombe KR, Threlfell S, Mann EO, Cragg SJ. Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter. Nature Communications. 10: 4263. PMID 31537790 DOI: 10.1038/S41467-019-12264-9  0.833
2019 Brimblecombe KR, Vietti-Michelina S, Platt NJ, Kastli R, Hnieno A, Gracie CJ, Cragg SJ. Calbindin-D28K Limits Dopamine Release in Ventral but Not Dorsal Striatum by Regulating Ca Availability and Dopamine Transporter Function. Acs Chemical Neuroscience. PMID 31361457 DOI: 10.1021/acschemneuro.9b00325  0.874
2019 Pristerà A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, Cragg S, Guillemot F, Ang SL. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proceedings of the National Academy of Sciences of the United States of America. 116: 3817-3826. PMID 30808767 DOI: 10.1073/Pnas.1806820116  0.841
2018 Lopes EF, Roberts BM, Siddorn RE, Clements MA, Cragg SJ. Inhibition of nigrostriatal dopamine release by striatal GABA and GABA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30541909 DOI: 10.1523/JNEUROSCI.2028-18.2018  0.837
2018 Brimblecombe KR, Threlfell S, Dautan D, Kosillo P, Mena-Segovia J, Cragg SJ. Targeted Activation of Cholinergic Interneurons Accounts for the Modulation of Dopamine by Striatal Nicotinic Receptors. Eneuro. 5. PMID 30406189 DOI: 10.1523/ENEURO.0397-17.2018  0.854
2018 Zhang YF, Reynolds JNJ, Cragg SJ. Pauses in Cholinergic Interneuron Activity Are Driven by Excitatory Input and Delayed Rectification, with Dopamine Modulation. Neuron. PMID 29754751 DOI: 10.1016/j.neuron.2018.04.027  0.584
2017 Zhang YF, Cragg SJ. Pauses in Striatal Cholinergic Interneurons: What is Revealed by Their Common Themes and Variations? Frontiers in Systems Neuroscience. 11: 80. PMID 29163075 DOI: 10.3389/fnsys.2017.00080  0.574
2016 Brimblecombe KR, Cragg SJ. The Striosome and Matrix Compartments of the Striatum: A Path through the Labyrinth from Neurochemistry toward Function. Acs Chemical Neuroscience. PMID 27977131 DOI: 10.1021/acschemneuro.6b00333  0.793
2016 Kosillo P, Zhang YF, Threlfell S, Cragg SJ. Cortical Control of Striatal Dopamine Transmission via Striatal Cholinergic Interneurons. Cerebral Cortex (New York, N.Y. : 1991). PMID 27566978 DOI: 10.1093/cercor/bhw252  0.848
2016 Sulzer D, Cragg SJ, Rice ME. Striatal dopamine neurotransmission: regulation of release and uptake. Basal Ganglia. 6: 123-148. PMID 27141430 DOI: 10.1016/j.baga.2016.02.001  0.749
2016 Dodson PD, Dreyer JK, Jennings KA, Syed EC, Wade-Martins R, Cragg SJ, Bolam JP, Magill PJ. Representation of spontaneous movement by dopaminergic neurons is cell-type selective and disrupted in parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001837 DOI: 10.1073/Pnas.1515941113  0.523
2016 Sloan M, Alegre-Abarrategui J, Potgieter D, Kaufmann AK, Exley R, Deltheil T, Threlfell S, Connor-Robson N, Brimblecombe K, Wallings R, Cioroch M, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, et al. LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. Human Molecular Genetics. PMID 26744332 DOI: 10.1093/Hmg/Ddv628  0.833
2015 Pristerà A, Lin W, Kaufmann AK, Brimblecombe KR, Threlfell S, Dodson PD, Magill PJ, Fernandes C, Cragg SJ, Ang SL. Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 112: E4929-38. PMID 26283356 DOI: 10.1073/Pnas.1503911112  0.821
2015 Jennings KA, Platt NJ, Cragg SJ. The impact of a parkinsonian lesion on dynamic striatal dopamine transmission depends on nicotinic receptor activation. Neurobiology of Disease. 82: 262-8. PMID 26117304 DOI: 10.1016/j.nbd.2015.06.015  0.881
2015 Brimblecombe KR, Cragg SJ. Substance P Weights Striatal Dopamine Transmission Differently within the Striosome-Matrix Axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9017-23. PMID 26085627 DOI: 10.1523/JNEUROSCI.0870-15.2015  0.857
2015 Hunn BH, Cragg SJ, Bolam JP, Spillantini MG, Wade-Martins R. Impaired intracellular trafficking defines early Parkinson's disease. Trends in Neurosciences. 38: 178-88. PMID 25639775 DOI: 10.1016/J.Tins.2014.12.009  0.417
2015 Brimblecombe KR, Gracie CJ, Platt NJ, Cragg SJ. Gating of dopamine transmission by calcium and axonal N-, Q-, T- and L-type voltage-gated calcium channels differs between striatal domains. The Journal of Physiology. 593: 929-46. PMID 25533038 DOI: 10.1113/jphysiol.2014.285890  0.826
2015 Brimblecombe KR, Cragg SJ. Ni(2+) affects dopamine uptake which limits suitability as inhibitor of T-type voltage-gated Ca(2+) channels. Acs Chemical Neuroscience. 6: 124-9. PMID 25434848 DOI: 10.1021/cn500274g  0.836
2015 Jennings KA, Platt NJ, Cragg SJ. The impact of a parkinsonian lesion on dynamic striatal dopamine transmission depends on nicotinic receptor activation Neurobiology of Disease. 82: 262-268. DOI: 10.1016/j.nbd.2015.06.015  0.495
2014 Taylor TN, Potgieter D, Anwar S, Senior SL, Janezic S, Threlfell S, Ryan B, Parkkinen L, Deltheil T, Cioroch M, Livieratos A, Oliver PL, Jennings KA, Davies KE, Ansorge O, ... ... Cragg SJ, et al. Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse. Neurobiology of Disease. 62: 193-207. PMID 24121116 DOI: 10.1016/J.Nbd.2013.10.005  0.84
2013 Janezic S, Threlfell S, Dodson PD, Dowie MJ, Taylor TN, Potgieter D, Parkkinen L, Senior SL, Anwar S, Ryan B, Deltheil T, Kosillo P, Cioroch M, Wagner K, Ansorge O, ... ... Cragg SJ, et al. Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. Proceedings of the National Academy of Sciences of the United States of America. 110: E4016-25. PMID 24082145 DOI: 10.1073/Pnas.1309143110  0.846
2013 Exley R, Clements MA, Hartung H, McIntosh JM, Franklin M, Bermudez I, Cragg SJ. Striatal dopamine transmission is reduced after chronic nicotine with a decrease in α6-nicotinic receptor control in nucleus accumbens. The European Journal of Neuroscience. 38: 3036-43. PMID 23841846 DOI: 10.1111/ejn.12298  0.84
2013 Cotel F, Exley R, Cragg SJ, Perrier JF. Serotonin spillover onto the axon initial segment of motoneurons induces central fatigue by inhibiting action potential initiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 4774-9. PMID 23487756 DOI: 10.1073/pnas.1216150110  0.787
2012 Threlfell S, Lalic T, Platt NJ, Jennings KA, Deisseroth K, Cragg SJ. Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons. Neuron. 75: 58-64. PMID 22794260 DOI: 10.1016/j.neuron.2012.04.038  0.87
2012 Platt NJ, Gispert S, Auburger G, Cragg SJ. Striatal dopamine transmission is subtly modified in human A53Tα-synuclein overexpressing mice. Plos One. 7: e36397. PMID 22570709 DOI: 10.1371/journal.pone.0036397  0.88
2012 Exley R, McIntosh JM, Marks MJ, Maskos U, Cragg SJ. Striatal α5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2352-6. PMID 22396410 DOI: 10.1523/JNEUROSCI.4985-11.2012  0.858
2011 Rice ME, Patel JC, Cragg SJ. Dopamine release in the basal ganglia. Neuroscience. 198: 112-37. PMID 21939738 DOI: 10.1016/j.neuroscience.2011.08.066  0.749
2011 Anwar S, Peters O, Millership S, Ninkina N, Doig N, Connor-Robson N, Threlfell S, Kooner G, Deacon RM, Bannerman DM, Bolam JP, Chandra SS, Cragg SJ, Wade-Martins R, Buchman VL. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7264-74. PMID 21593311 DOI: 10.1523/Jneurosci.6194-10.2011  0.874
2011 Hartung H, Threlfell S, Cragg SJ. Nitric oxide donors enhance the frequency dependence of dopamine release in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1811-22. PMID 21508928 DOI: 10.1038/npp.2011.62  0.872
2011 Exley R, Maubourguet N, David V, Eddine R, Evrard A, Pons S, Marti F, Threlfell S, Cazala P, McIntosh JM, Changeux JP, Maskos U, Cragg SJ, Faure P. Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proceedings of the National Academy of Sciences of the United States of America. 108: 7577-82. PMID 21502501 DOI: 10.1073/Pnas.1103000108  0.809
2011 Threlfell S, Cragg SJ. Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons. Frontiers in Systems Neuroscience. 5: 11. PMID 21427783 DOI: 10.3389/fnsys.2011.00011  0.878
2010 Threlfell S, Clements MA, Khodai T, Pienaar IS, Exley R, Wess J, Cragg SJ. Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3398-408. PMID 20203199 DOI: 10.1523/Jneurosci.5620-09.2010  0.857
2010 Threlfell S, Greenfield SA, Cragg SJ. 5-HT(1B) receptor regulation of serotonin (5-HT) release by endogenous 5-HT in the substantia nigra. Neuroscience. 165: 212-20. PMID 19819310 DOI: 10.1016/j.neuroscience.2009.10.005  0.792
2009 Hájos N, Ellender TJ, Zemankovics R, Mann EO, Exley R, Cragg SJ, Freund TF, Paulsen O. Maintaining network activity in submerged hippocampal slices: importance of oxygen supply. The European Journal of Neuroscience. 29: 319-27. PMID 19200237 DOI: 10.1111/J.1460-9568.2008.06577.X  0.771
2008 Threlfell S, Exley R, Cragg SJ, Greenfield SA. Constitutive histamine H2 receptor activity regulates serotonin release in the substantia nigra. Journal of Neurochemistry. 107: 745-55. PMID 18761715 DOI: 10.1111/j.1471-4159.2008.05646.x  0.79
2008 Rice ME, Cragg SJ. Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway. Brain Research Reviews. 58: 303-13. PMID 18433875 DOI: 10.1016/j.brainresrev.2008.02.004  0.735
2008 Senior SL, Ninkina N, Deacon R, Bannerman D, Buchman VL, Cragg SJ, Wade-Martins R. Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein. The European Journal of Neuroscience. 27: 947-57. PMID 18333965 DOI: 10.1111/j.1460-9568.2008.06055.x  0.53
2008 Exley R, Cragg SJ. Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission. British Journal of Pharmacology. 153: S283-97. PMID 18037926 DOI: 10.1038/sj.bjp.0707510  0.633
2008 Exley R, Clements MA, Hartung H, McIntosh JM, Cragg SJ. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2158-66. PMID 18033235 DOI: 10.1038/sj.npp.1301617  0.84
2006 Ungless MA, Cragg SJ. A choreography of nicotinic receptors directs the dopamine neuron routine. Neuron. 50: 815-6. PMID 16772163 DOI: 10.1016/j.neuron.2006.05.024  0.543
2006 Cragg SJ. Meaningful silences: how dopamine listens to the ACh pause. Trends in Neurosciences. 29: 125-31. PMID 16443285 DOI: 10.1016/j.tins.2006.01.003  0.605
2005 Cragg SJ. Singing to the tune of dopamine. Focus on "Properties of dopamine release and uptake in the songbird basal ganglia". Journal of Neurophysiology. 93: 1827-8. PMID 15774708 DOI: 10.1152/jn.01210.2004  0.542
2005 Cragg SJ, Rice ME. Somatodendritic dopamine release in midbrain Dendritic Neurotransmitter Release. 69-83. DOI: 10.1007/0-387-23696-1_5  0.701
2004 Threlfell S, Cragg SJ, Kalló I, Turi GF, Coen CW, Greenfield SA. Histamine H3 receptors inhibit serotonin release in substantia nigra pars reticulata. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8704-10. PMID 15470136 DOI: 10.1523/JNEUROSCI.2690-04.2004  0.821
2004 Cragg SJ, Baufreton J, Xue Y, Bolam JP, Bevan MD. Synaptic release of dopamine in the subthalamic nucleus. The European Journal of Neuroscience. 20: 1788-802. PMID 15380000 DOI: 10.1111/J.1460-9568.2004.03629.X  0.575
2004 Rice ME, Cragg SJ. Nicotine amplifies reward-related dopamine signals in striatum. Nature Neuroscience. 7: 583-4. PMID 15146188 DOI: 10.1038/nn1244  0.67
2004 Cragg SJ, Rice ME. DAncing past the DAT at a DA synapse. Trends in Neurosciences. 27: 270-7. PMID 15111009 DOI: 10.1016/j.tins.2004.03.011  0.685
2003 Cragg SJ. Variable dopamine release probability and short-term plasticity between functional domains of the primate striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4378-85. PMID 12764127  0.54
2002 Rice ME, Forman RE, Chen BT, Avshalumov MV, Cragg SJ, Drew KL. Brain antioxidant regulation in mammals and anoxia-tolerant reptiles: balanced for neuroprotection and neuromodulation. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 133: 515-25. PMID 12458180 DOI: 10.1016/S1532-0456(02)00116-3  0.602
2002 Cragg SJ, Hille CJ, Greenfield SA. Functional domains in dorsal striatum of the nonhuman primate are defined by the dynamic behavior of dopamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5705-12. PMID 12097522  0.718
2001 Cragg SJ, Nicholson C, Kume-Kick J, Tao L, Rice ME. Dopamine-mediated volume transmission in midbrain is regulated by distinct extracellular geometry and uptake. Journal of Neurophysiology. 85: 1761-71. PMID 11287497 DOI: 10.1152/jn.2001.85.4.1761  0.735
2000 Cragg SJ, Hille CJ, Greenfield SA. Dopamine release and uptake dynamics within nonhuman primate striatum in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8209-17. PMID 11050144  0.727
2000 Cragg SJ, Clarke DJ, Greenfield SA. Real-time dynamics of dopamine released from neuronal transplants in experimental Parkinson's disease. Experimental Neurology. 164: 145-53. PMID 10877925 DOI: 10.1006/exnr.2000.7420  0.752
1999 Emilien G, Maloteaux JM, Geurts M, Hoogenberg K, Cragg S. Dopamine receptors--physiological understanding to therapeutic intervention potential. Pharmacology & Therapeutics. 84: 133-56. PMID 10596903 DOI: 10.1016/S0163-7258(99)00029-7  0.487
1998 Cragg SJ, Holmes C, Hawkey CR, Greenfield SA. Dopamine is released spontaneously from developing midbrain neurons in organotypic culture. Neuroscience. 84: 325-30. PMID 9539208 DOI: 10.1016/S0306-4522(97)00657-X  0.775
1997 Cragg SJ, Hawkey CR, Greenfield SA. Comparison of serotonin and dopamine release in substantia nigra and ventral tegmental area: region and species differences. Journal of Neurochemistry. 69: 2378-86. PMID 9375669  0.697
1997 Cragg SJ, Greenfield SA. Differential autoreceptor control of somatodendritic and axon terminal dopamine release in substantia nigra, ventral tegmental area, and striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5738-46. PMID 9221772  0.728
1997 Cragg S, Rice ME, Greenfield SA. Heterogeneity of electrically evoked dopamine release and reuptake in substantia nigra, ventral tegmental area, and striatum. Journal of Neurophysiology. 77: 863-73. PMID 9065855 DOI: 10.1152/Jn.1997.77.2.863  0.789
1997 Rice ME, Cragg SJ, Greenfield SA. Characteristics of electrically evoked somatodendritic dopamine release in substantia nigra and ventral tegmental area in vitro. Journal of Neurophysiology. 77: 853-62. PMID 9065854 DOI: 10.1152/Jn.1997.77.2.853  0.801
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