| Year |
Citation |
Score |
| 2024 |
Alberto-Silva AS, Hemmer S, Bock HA, da Silva LA, Scott KR, Kastner N, Bhatt M, Niello M, Jäntsch K, Kudlacek O, Bossi E, Stockner T, Meyer MR, McCorvy JD, Brandt SD, et al. Bioisosteric analogs of MDMA: Improving the pharmacological profile? Journal of Neurochemistry. PMID 38898705 DOI: 10.1111/jnc.16149 |
0.312 |
|
| 2024 |
Denomme N, Hernandez CC, Bock HA, Ohana RF, Bakshi S, Sherwood AM, McCorvy JD, Daley PF, Callaway WB, Hull JM, Alt A, Isom LL, Cozzi NV. . Molecular Pharmacology. PMID 38821630 DOI: 10.1124/molpharm.123.000837 |
0.364 |
|
| 2024 |
Schlimgen RR, Peterson FC, Heukers R, Smit MJ, McCorvy JD, Volkman BF. Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies. Nature Communications. 15: 4611. PMID 38816420 DOI: 10.1038/s41467-024-49000-x |
0.311 |
|
| 2024 |
Alberto-Silva AS, Hemmer S, Bock HA, Alves da Silva L, Scott KR, Kastner N, Bhatt M, Niello M, Jäntsch K, Kudlacek O, Bossi E, Stockner T, Meyer MR, McCorvy JD, Brandt SD, et al. Bioisosteric analogs of MDMA with improved pharmacological profile. Biorxiv : the Preprint Server For Biology. PMID 38645142 DOI: 10.1101/2024.04.08.588083 |
0.301 |
|
| 2023 |
Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, ... ... McCorvy JD, et al. Identification of 5-HT receptor signaling pathways associated with psychedelic potential. Nature Communications. 14: 8221. PMID 38102107 DOI: 10.1038/s41467-023-44016-1 |
0.401 |
|
| 2023 |
Rodriguez P, Laskowski LJ, Pallais JP, Bock HA, Cavalco NG, Anderson EI, Calkins MM, Razzoli M, Sham YY, McCorvy JD, Bartolomucci A. Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism. The Journal of Biological Chemistry. 105549. PMID 38072064 DOI: 10.1016/j.jbc.2023.105549 |
0.304 |
|
| 2023 |
Cameron LP, Benetatos J, Lewis V, Bonniwell EM, Jaster AM, Moliner R, Castrén E, McCorvy JD, Palner M, Aguilar-Valles A. Beyond the 5-HT Receptor: Classic and Nonclassic Targets in Psychedelic Drug Action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 43: 7472-7482. PMID 37940583 DOI: 10.1523/JNEUROSCI.1384-23.2023 |
0.413 |
|
| 2023 |
Kelly TJ, Bonniwell EM, Mu L, Liu X, Hu Y, Friedman V, Yu H, Su W, McCorvy JD, Liu QS. Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37752222 DOI: 10.1038/s41386-023-01744-8 |
0.303 |
|
| 2023 |
Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, ... ... McCorvy JD, et al. Identification of 5-HT Receptor Signaling Pathways Responsible for Psychedelic Potential. Biorxiv : the Preprint Server For Biology. PMID 37577474 DOI: 10.1101/2023.07.29.551106 |
0.399 |
|
| 2023 |
Tosh DK, Calkins MM, Ivancich MS, Bock HA, Campbell RG, Lewicki SA, Chen E, Gao ZG, McCorvy JD, Jacobson KA. Structure activity relationships of 5-HT and 5-HT serotonin receptor antagonists: N, C2 and 5'-Modified (N)-methanocarba-adenosine derivatives. European Journal of Medicinal Chemistry. 259: 115691. PMID 37562117 DOI: 10.1016/j.ejmech.2023.115691 |
0.36 |
|
| 2023 |
Malcolm NJ, Palkovic B, Sprague DJ, Calkins MM, Lanham JK, Halberstadt AL, Stucke AG, McCorvy JD. Mu-opioid receptor selective superagonists produce prolonged respiratory depression. Iscience. 26: 107121. PMID 37416459 DOI: 10.1016/j.isci.2023.107121 |
0.683 |
|
| 2023 |
Lewis V, Bonniwell EM, Lanham JK, Ghaffari A, Sheshbaradaran H, Cao AB, Calkins MM, Bautista-Carro MA, Arsenault E, Telfer A, Taghavi-Abkuh FF, Malcolm NJ, El Sayegh F, Abizaid A, Schmid Y, ... ... McCorvy JD, et al. A non-hallucinogenic LSD analog with therapeutic potential for mood disorders. Cell Reports. 42: 112203. PMID 36884348 DOI: 10.1016/j.celrep.2023.112203 |
0.352 |
|
| 2023 |
Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE. Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Science (New York, N.Y.). 379: 700-706. PMID 36795823 DOI: 10.1126/science.adf0435 |
0.344 |
|
| 2023 |
Yahya NA, Lanham JK, Sprague DJ, Palygin O, McCorvy JD, Marchant JS. Molecular and cellular basis of praziquantel action in the cardiovascular system. American Journal of Physiology. Cell Physiology. PMID 36622066 DOI: 10.1152/ajpcell.00520.2022 |
0.736 |
|
| 2022 |
Cunningham MJ, Bock HA, Serrano IC, Bechand B, Vidyadhara DJ, Bonniwell EM, Lankri D, Duggan P, Nazarova AL, Cao AB, Calkins MM, Khirsariya P, Hwu C, Katritch V, Chandra SS, ... McCorvy JD, et al. Pharmacological Mechanism of the Non-hallucinogenic 5-HT Agonist Ariadne and Analogs. Acs Chemical Neuroscience. PMID 36521179 DOI: 10.1021/acschemneuro.2c00597 |
0.431 |
|
| 2022 |
Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, et al. Bespoke library docking for 5-HT receptor agonists with antidepressant activity. Nature. PMID 36171289 DOI: 10.1038/s41586-022-05258-z |
0.466 |
|
| 2022 |
Fisher CL, Fallot LB, Wan TC, Keyes RF, Suresh RR, Rothwell AC, Gao ZG, McCorvy JD, Smith BC, Jacobson KA, Auchampach JA. Characterization of Dual-Acting A Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gα and Gα Isoprotein Activation. Acs Pharmacology & Translational Science. 5: 625-641. PMID 35983277 DOI: 10.1021/acsptsci.2c00076 |
0.568 |
|
| 2022 |
Fisher CL, Wan TC, Fallot LB, Keyes RF, Suresh RR, Rothwell AC, Gao ZG, McCorvy JD, Smith BC, Jacobson KA, Auchampach JA. Characterization of Novel A Adenosine Receptor Allosteric Modulators. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552611 DOI: 10.1096/fasebj.2022.36.S1.00R64 |
0.404 |
|
| 2022 |
Schlimgen R, Peterson F, Heukers R, Smit M, McCorvy J, Volkman B. Structural Basis of Nanobody Induced ACKR3 Inhibition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552343 DOI: 10.1096/fasebj.2022.36.S1.R4707 |
0.341 |
|
| 2022 |
Orr MJ, Cao AB, Wang CT, Gaisin A, Csakai A, Friswold AP, Meltzer HY, McCorvy JD, Scheidt KA. Discovery of Highly Potent Serotonin 5-HT Receptor Agonists Inspired by Heteroyohimbine Natural Products. Acs Medicinal Chemistry Letters. 13: 648-657. PMID 35450369 DOI: 10.1021/acsmedchemlett.1c00694 |
0.419 |
|
| 2021 |
Rudin D, McCorvy JD, Glatfelter GC, Luethi D, Szöllősi D, Ljubišić T, Kavanagh PV, Dowling G, Holy M, Jaentsch K, Walther D, Brandt SD, Stockner T, Baumann MH, Halberstadt AL, et al. (2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34750565 DOI: 10.1038/s41386-021-01221-0 |
0.315 |
|
| 2021 |
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, McCorvy JD, Halberstadt AL. Investigation of the Structure-Activity Relationships of Psilocybin Analogues. Acs Pharmacology & Translational Science. 4: 533-542. PMID 33860183 DOI: 10.1021/acsptsci.0c00176 |
0.397 |
|
| 2021 |
Martini ML, Ray C, Yu X, Liu J, Pogorelov VM, Wetsel WC, Huang XP, McCorvy JD, Caron MG, Jin J. Addition to "Designing Functionally Selective Noncatechol Dopamine D Receptor Agonists with Potent In Vivo Antiparkinsonian Activity". Acs Chemical Neuroscience. PMID 33830725 DOI: 10.1021/acschemneuro.1c00186 |
0.473 |
|
| 2020 |
Wedemeyer MJ, Mahn SA, Getschman AE, Crawford KS, Peterson FC, Marchese A, McCorvy JD, Volkman BF. The chemokine X-factor: structure-function analysis of the CXC motif at CXCR4 and ACKR3. The Journal of Biological Chemistry. PMID 32788219 DOI: 10.1074/Jbc.Ra120.014244 |
0.334 |
|
| 2020 |
Patel N, Huang XP, Grandner J, Johansson LC, Stauch B, McCorvy JD, Liu Y, Roth B, Katritch V. Structure-based discovery of potent and selective melatonin receptor agonists. Elife. 9. PMID 32118583 DOI: 10.7554/Elife.53779 |
0.425 |
|
| 2020 |
Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P. Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin. Journal of Natural Products. PMID 32077284 DOI: 10.1021/Acs.Jnatprod.9B01061 |
0.325 |
|
| 2020 |
Stein RM, Kang HJ, McCorvy JD, Glatfelter GC, Jones AJ, Che T, Slocum S, Huang XP, Savych O, Moroz YS, Stauch B, Johansson LC, Cherezov V, Kenakin T, Irwin JJ, et al. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. Nature. PMID 32040955 DOI: 10.1038/s41586-020-2027-0 |
0.357 |
|
| 2019 |
Halberstadt AL, Chatha M, Klein AK, McCorvy JD, Meyer MR, Wagmann L, Stratford A, Brandt SD. Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD). Neuropharmacology. 107856. PMID 31756337 DOI: 10.1016/J.Neuropharm.2019.107856 |
0.408 |
|
| 2019 |
Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, Mahata SK, O'Grady S, McCorvy JD, Baier LJ, Sham YY, et al. Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21. Cell Reports. 28: 2567-2580.e6. PMID 31484069 DOI: 10.1016/J.Celrep.2019.07.101 |
0.323 |
|
| 2019 |
Zhang G, McCorvy JD, Shen S, Cheng J, Roth BL, Kozikowski AP. Design of fluorinated cyclopropane derivatives of 2-phenylcyclopropylmethylamine leading to identification of a selective serotonin 2C (5-HT) receptor agonist without 5-HT agonism. European Journal of Medicinal Chemistry. 182: 111626. PMID 31445232 DOI: 10.1016/J.Ejmech.2019.111626 |
0.431 |
|
| 2019 |
Martini ML, Ray C, Yu X, Liu J, Pogorelov V, Wetsel WC, Huang XP, McCorvy J, Caron MG, Jin J. Designing Functionally Selective Non-Catechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity. Acs Chemical Neuroscience. PMID 31387346 DOI: 10.1021/Acschemneuro.9B00410 |
0.425 |
|
| 2019 |
Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, et al. Structural basis of ligand recognition at the human MT melatonin receptor. Nature. PMID 31019306 DOI: 10.1038/S41586-019-1141-3 |
0.439 |
|
| 2019 |
Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang XP, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, et al. XFEL structures of the human MT melatonin receptor reveal the basis of subtype selectivity. Nature. PMID 31019305 DOI: 10.1038/s41586-019-1144-0 |
0.417 |
|
| 2019 |
Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J. D2 Dopamine Receptor G protein-biased Partial Agonists Based on Cariprazine. Journal of Medicinal Chemistry. PMID 30964661 DOI: 10.1021/Acs.Jmedchem.9B00508 |
0.442 |
|
| 2019 |
Martini ML, Liu J, Ray C, Yu X, Huang XP, Urs A, Urs NM, McCorvy J, Caron MG, Roth BL, Jin J. Defining Structure-Functional Selectivity Relationships (SFSR) for a Class of Non-Catechol Dopamine D1 Receptor Agonists. Journal of Medicinal Chemistry. PMID 30875219 DOI: 10.1021/Acs.Jmedchem.9B00351 |
0.433 |
|
| 2018 |
McCorvy JD, Wacker D, Wang S, Agegnehu B, Liu J, Lansu K, Tribo AR, Olsen RHJ, Che T, Jin J, Roth BL. Structural determinants of 5-HT receptor activation and biased agonism. Nature Structural & Molecular Biology. PMID 30127358 DOI: 10.1038/S41594-018-0116-7 |
0.449 |
|
| 2018 |
Tan L, Yan W, McCorvy JD, Cheng J. Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential. Journal of Medicinal Chemistry. PMID 29939744 DOI: 10.1021/acs.jmedchem.8b00435 |
0.388 |
|
| 2018 |
Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, et al. High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. Chemical Science. 9: 3192-3199. PMID 29732102 DOI: 10.1039/C7Sc04698G |
0.34 |
|
| 2018 |
Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, et al. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell. PMID 29398112 DOI: 10.1016/J.Cell.2018.01.001 |
0.442 |
|
| 2018 |
Che T, Majumdar S, Zaidi SA, Ondachi P, McCorvy JD, Wang S, Mosier PD, Uprety R, Vardy E, Krumm BE, Han GW, Lee MY, Pardon E, Steyaert J, Huang XP, et al. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell. PMID 29307491 DOI: 10.1016/J.Cell.2017.12.011 |
0.319 |
|
| 2017 |
Chan JD, Cupit PM, Gunaratne GS, McCorvy JD, Yang Y, Stoltz K, Webb TR, Dosa PI, Roth BL, Abagyan R, Cunningham C, Marchant JS. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nature Communications. 8: 1910. PMID 29208933 DOI: 10.1038/S41467-017-02084-0 |
0.568 |
|
| 2017 |
Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science (New York, N.Y.). 358: 381-386. PMID 29051383 DOI: 10.1126/Science.Aan5468 |
0.474 |
|
| 2017 |
Zhang G, Cheng J, McCorvy JD, Lorello PJ, Caldarone BJ, Roth BL, Kozikowski AP. Discovery of N-Substituted 2-Phenylcyclopropylmethylamines as Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists for Potential Use as Antipsychotic Medications. Journal of Medicinal Chemistry. PMID 28657744 DOI: 10.1021/Acs.Jmedchem.7B00584 |
0.406 |
|
| 2017 |
Brandt SD, Kavanagh PV, Twamley B, Westphal F, Elliott SP, Wallach J, Stratford A, Klein LM, McCorvy JD, Nichols DE, Halberstadt AL. Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775). Drug Testing and Analysis. PMID 28585392 DOI: 10.1002/Dta.2222 |
0.504 |
|
| 2017 |
Hoehn RD, Nichols DE, McCorvy JD, Neven H, Kais S. Experimental evaluation of the generalized vibrational theory of G protein-coupled receptor activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28500275 DOI: 10.1073/Pnas.1618422114 |
0.597 |
|
| 2017 |
Jensen AA, McCorvy JD, Petersen SL, Bundgaard C, Liebscher G, Kenakin TP, Brauner-Osborne H, Kehler J, Kristensen JL. Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist. The Journal of Pharmacology and Experimental Therapeutics. PMID 28360333 DOI: 10.1124/jpet.117.239905 |
0.451 |
|
| 2017 |
Lansu K, Karpiak J, Liu J, Huang XP, McCorvy JD, Kroeze WK, Che T, Nagase H, Carroll FI, Jin J, Shoichet BK, Roth BL. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nature Chemical Biology. PMID 28288109 DOI: 10.1038/Nchembio.2334 |
0.354 |
|
| 2017 |
Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell. 168: 377-389.e12. PMID 28129538 DOI: 10.1016/J.Cell.2016.12.033 |
0.589 |
|
| 2016 |
Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911814 DOI: 10.1073/Pnas.1614347113 |
0.397 |
|
| 2016 |
Chen X, McCorvy JD, Fischer MG, Butler KV, Shen Y, Roth BL, Jin J. Discovery of G Protein-biased D2 Dopamine Receptor Partial Agonists. Journal of Medicinal Chemistry. PMID 27805392 DOI: 10.1021/acs.jmedchem.6b01208 |
0.436 |
|
| 2016 |
Cheng J, McCorvy JD, Giguère PM, Zhu H, Kenakin T, Roth BL, Kozikowski AP. Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists. Journal of Medicinal Chemistry. PMID 27726356 DOI: 10.1021/Acs.Jmedchem.6B01194 |
0.426 |
|
| 2016 |
Chan JD, McCorvy JD, Acharya S, Johns ME, Day TA, Roth BL, Marchant JS. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. Plos Pathogens. 12: e1005651. PMID 27187180 DOI: 10.1371/Journal.Ppat.1005651 |
0.596 |
|
| 2015 |
Cheng J, Giguère PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP. Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. Journal of Medicinal Chemistry. PMID 26704965 DOI: 10.1021/Acs.Jmedchem.5B01153 |
0.365 |
|
| 2015 |
McCorvy JD, Roth BL. Structure and function of serotonin G protein-coupled receptors. Pharmacology & Therapeutics. 150: 129-42. PMID 25601315 DOI: 10.1016/j.pharmthera.2015.01.009 |
0.402 |
|
| 2015 |
Hansen M, Jacobsen SE, Plunkett S, Liebscher GE, McCorvy JD, Bräuner-Osborne H, Kristensen JL. Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists. Bioorganic & Medicinal Chemistry. 23: 3933-7. PMID 25583099 DOI: 10.1016/j.bmc.2014.12.011 |
0.456 |
|
| 2013 |
Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC. Structural features for functional selectivity at serotonin receptors. Science (New York, N.Y.). 340: 615-9. PMID 23519215 DOI: 10.1126/Science.1232808 |
0.395 |
|
| 2013 |
Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, et al. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). 340: 610-4. PMID 23519210 DOI: 10.1126/Science.1232807 |
0.493 |
|
| 2013 |
Juncosa JI, Hansen M, Bonner LA, Cueva JP, Maglathlin R, McCorvy JD, Marona-Lewicka D, Lill MA, Nichols DE. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. Acs Chemical Neuroscience. 4: 96-109. PMID 23336049 DOI: 10.1021/Cn3000668 |
0.682 |
|
| 2012 |
Pigott A, Frescas S, McCorvy JD, Huang XP, Roth BL, Nichols DE. trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT(2) receptor family. Beilstein Journal of Organic Chemistry. 8: 1705-9. PMID 23209503 DOI: 10.3762/Bjoc.8.194 |
0.666 |
|
| 2012 |
Clark AH, McCorvy JD, Conley JM, Williams WK, Bekkam M, Watts VJ, Nichols DE. Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D₃ receptor-selective full agonist ligand. Bioorganic & Medicinal Chemistry. 20: 6366-74. PMID 23018094 DOI: 10.1016/J.Bmc.2012.08.058 |
0.728 |
|
| 2012 |
McCorvy JD, Watts VJ, Nichols DE. Comparison of the D₁ dopamine full agonists, dihydrexidine and doxanthrine, in the 6-OHDA rat model of Parkinson's disease. Psychopharmacology. 222: 81-7. PMID 22222862 DOI: 10.1007/S00213-011-2625-5 |
0.577 |
|
| 2011 |
Clark AH, McCorvy JD, Watts VJ, Nichols DE. Assessment of dopamine D₁ receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393. Bioorganic & Medicinal Chemistry. 19: 5420-31. PMID 21862338 DOI: 10.1016/J.Bmc.2011.07.057 |
0.749 |
|
| 2011 |
McCorvy JD, Harland AA, Maglathlin R, Nichols DE. A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference. Neuroscience Letters. 505: 10-3. PMID 21827831 DOI: 10.1016/J.Neulet.2011.07.036 |
0.645 |
|
| 2011 |
Clark LH, Cueva JP, McCorvy JD, Harland AA, Watts VJ, Nichols DE. C-Ring expanded analogs of doxanthrine: Conformation plays a critical role Arkivoc. 2010: 125-138. DOI: 10.3998/Ark.5550190.0011.411 |
0.759 |
|
| 2009 |
Przybyla JA, Cueva JP, Chemel BR, Hsu KJ, Riese DJ, McCorvy JD, Chester JA, Nichols DE, Watts VJ. Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D(1) receptor agonist, and a reversal of enantioselectivity at D(1) versus alpha(2C) adrenergic receptors. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 138-46. PMID 19028082 DOI: 10.1016/J.Euroneuro.2008.10.002 |
0.684 |
|
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