Year |
Citation |
Score |
2013 |
Day DR, Jabaiah S, Jacobs RS, Little RD. Cyclodextrin formulation of the marine natural product pseudopterosin A uncovers optimal pharmacodynamics in proliferation studies of human umbilical vein endothelial cells. Marine Drugs. 11: 3258-71. PMID 24065164 DOI: 10.3390/Md11093258 |
0.663 |
|
2010 |
Flachsmann F, Schellhaas K, Moya CE, Jacobs RS, Fenical W. Synthetic pseudopterosin analogues: A novel class of antiinflammatory drug candidates. Bioorganic & Medicinal Chemistry. 18: 8324-33. PMID 21041093 DOI: 10.1016/J.Bmc.2010.09.067 |
0.737 |
|
2008 |
Zhong W, Moya C, Jacobs RS, Little RD. Synthesis and an evaluation of the bioactivity of the C-glycoside of pseudopterosin A methyl ether. The Journal of Organic Chemistry. 73: 7011-6. PMID 18710290 DOI: 10.1021/Jo801432T |
0.724 |
|
2008 |
Hoarau C, Day D, Moya C, Wu G, Hackim A, Jacobs RS, Little RD. iso-PsE, a new pseudopterosin Tetrahedron Letters. 49: 4604-4606. DOI: 10.1016/J.Tetlet.2008.05.106 |
0.74 |
|
2008 |
Tanis VM, Moya C, Jacobs RS, Little RD. Synthesis and evaluation of the bioactivity of simplified analogs of the seco-pseudopterosins; progress toward determining a pharmacophore Tetrahedron. 64: 10649-10663. DOI: 10.1016/J.Tet.2008.09.025 |
0.739 |
|
2007 |
Moya CE, Jacobs RS. Mechanism of action of the Pseudopterosins and their role in wound healing The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A427-D |
0.689 |
|
2006 |
Moya CE, Jacobs RS. Pseudopterosin A inhibits phagocytosis and alters intracellular calcium turnover in a pertussis toxin sensitive site in Tetrahymena thermophila. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 143: 436-43. PMID 16759914 DOI: 10.1016/J.Cbpc.2006.04.005 |
0.719 |
|
2006 |
Ross C, Küpper FC, Jacobs RS. Involvement of reactive oxygen species and reactive nitrogen species in the wound response of Dasycladus vermicularis. Chemistry & Biology. 13: 353-64. PMID 16632248 DOI: 10.1016/J.Chembiol.2006.01.009 |
0.541 |
|
2006 |
Mydlarz LD, Jacobs RS. An inducible release of reactive oxygen radicals in four species of gorgonian corals Marine and Freshwater Behaviour and Physiology. 39: 143-152. DOI: 10.1080/10236240600708512 |
0.635 |
|
2005 |
Santiago-Vázquez LZ, Jacobs RS. Comparison of fatty acid composition of cell homogenates and isolated chloroplasts in Acetabularia crenulata (Lamouroux). Zeitschrift FüR Naturforschung. C, Journal of Biosciences. 60: 757-63. PMID 16320619 DOI: 10.1515/Znc-2005-9-1015 |
0.731 |
|
2005 |
Ross C, Vreeland V, Waite JH, Jacobs RS. Rapid assembly of a wound plug: Stage one of a two-stage wound repair mechanism in the giant unicellular chlorophyte Dasycladus vermicularis (Chlorophyceae) Journal of Phycology. 41: 46-54. DOI: 10.1111/J.1529-8817.2005.04071.X |
0.508 |
|
2004 |
Mydlarz LD, Jacobs RS. Comparison of an inducible oxidative burst in free-living and symbiotic dinoflagellates reveals properties of the pseudopterosins Phytochemistry. 65: 3231-3241. PMID 15561188 DOI: 10.1016/J.Phytochem.2004.09.014 |
0.638 |
|
2004 |
Madari H, Jacobs RS. An analysis of cytotoxic botanical formulations used in the traditional medicine of ancient Persia as abortifacients. Journal of Natural Products. 67: 1204-10. PMID 15332833 DOI: 10.1021/Np049953R |
0.692 |
|
2004 |
Santiago-Vázquez LZ, Mydlarz LD, Pavlovich JG, Jacobs RS. Identification of hydroxy fatty acids by liquid chromatography-atmospheric pressure chemical ionization mass spectroscopy in Euglena gracilis Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 803: 233-236. PMID 15063330 DOI: 10.1016/J.Jchromb.2003.12.021 |
0.717 |
|
2003 |
Mydlarz LD, Jacobs RS, Boehnlein J, Kerr RG. Pseudopterosin biosynthesis in Symbiodinium sp., the dinoflagellate symbiont of Pseudopterogorgia elisabethae Chemistry and Biology. 10: 1051-1056. PMID 14652072 DOI: 10.1016/J.Chembiol.2003.10.012 |
0.648 |
|
2003 |
Madari H, Panda D, Wilson L, Jacobs RS. Dicoumarol: a unique microtubule stabilizing natural product that is synergistic with Taxol. Cancer Research. 63: 1214-20. PMID 12649179 |
0.704 |
|
2003 |
Ata A, Kerr RG, Moya CE, Jacobs RS. Identification of anti-inflammatory diterpenes from the marine gorgonian Pseudopterogorgia elisabethae Tetrahedron. 59: 4215-4222. DOI: 10.1016/S0040-4020(03)00515-5 |
0.747 |
|
2002 |
Stevenson CS, Capper EA, Roshak AK, Marquez B, Eichman C, Jackson JR, Mattern M, Gerwick WH, Jacobs RS, Marshall LA. The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore. The Journal of Pharmacology and Experimental Therapeutics. 303: 858-66. PMID 12388673 DOI: 10.1124/Jpet.102.036350 |
0.553 |
|
2002 |
Stevenson CS, Capper EA, Roshak AK, Marquez B, Grace K, Gerwick WH, Jacobs RS, Marshall LA. Scytonemin--a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 51: 112-4. PMID 11926312 DOI: 10.1007/Bf02684014 |
0.565 |
|
1999 |
Qureshi A, Stevenson CS, Albert CL, Jacobs RS, Faulkner DJ. Homo- and nor-plakotenin, new carboxylic acids from the Palauan sponge Plakortis lita. Journal of Natural Products. 62: 1205-7. PMID 10479343 DOI: 10.1021/np990164x |
0.504 |
|
1998 |
Mayer AM, Jacobson PB, Fenical W, Jacobs RS, Glaser KB. Pharmacological characterization of the pseudopterosins: novel anti-inflammatory natural products isolated from the Caribbean soft coral, Pseudopterogorgia elisabethae. Life Sciences. 62: PL401-7. PMID 9651113 DOI: 10.1016/S0024-3205(98)00229-X |
0.35 |
|
1997 |
McGough KA, Jackson JR, Minton JA, Marshall LA, Jacobs RS, Winkler JD. Inflammatory PGE2 production is maintained during hypoxia in rheumatoid synovial fibroblasts. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 46: S147-8. PMID 9297554 DOI: 10.1007/S000110050148 |
0.713 |
|
1994 |
Grace KJ, Zavortink D, Jacobs RS. Inactivation of bee venom phospholipase A2 by a sesquiterpene furanoic acid marine natural product. Biochemical Pharmacology. 47: 1427-34. PMID 8185650 DOI: 10.1016/0006-2952(94)90343-3 |
0.325 |
|
1993 |
Mayer AMS, Paul VJ, Fenical W, Norris JN, Carvalho MSd, Jacobs RS. Phospholipase A2 inhibitors from marine algae Hydrobiologia. 260: 521-529. DOI: 10.1007/978-94-011-1998-6_69 |
0.32 |
|
1992 |
Potts BCM, Faulkner DJ, De Carvalho MS, Jacobs RS. Chemical mechanism of inactivation of bee venom phospholipase A2 by the marine natural products manoalide, luffariellolide, and scalaradial Journal of the American Chemical Society. 114: 5093-5100. DOI: 10.1021/Ja00039A021 |
0.311 |
|
1991 |
de Carvalho MS, Jacobs RS. Two-step inactivation of bee venom phospholipase A2 by scalaradial. Biochemical Pharmacology. 42: 1621-6. PMID 1930288 DOI: 10.1016/0006-2952(91)90432-5 |
0.341 |
|
1990 |
Jacobson PB, Marshall LA, Sung A, Jacobs RS. Inactivation of human synovial fluid phospholipase A2 by the marine natural product, manoalide. Biochemical Pharmacology. 39: 1557-64. PMID 2337412 DOI: 10.1016/0006-2952(90)90521-L |
0.331 |
|
1989 |
Kernan MR, Faulkner DJ, Parkanyi L, Clardy J, de Carvalho MS, Jacobs RS. Luffolide, a novel anti-inflammatory terpene from the sponge Luffariella sp.. Experientia. 45: 388-90. PMID 2707379 DOI: 10.1007/Bf01957489 |
0.326 |
|
1987 |
Albizati KF, Holman T, Faulkner DJ, Glaser KB, Jacobs RS. Luffariellolide, an anti-inflammatory sesterterpene from the marine sponge Luffariella sp. Experientia. 43: 949-950. DOI: 10.1007/Bf01951682 |
0.345 |
|
1986 |
Look SA, Fenical W, Jacobs RS, Clardy J. The pseudopterosins: anti-inflammatory and analgesic natural products from the sea whip Pseudopterogorgia elisabethae. Proceedings of the National Academy of Sciences of the United States of America. 83: 6238-40. PMID 2875457 DOI: 10.1073/Pnas.83.17.6238 |
0.389 |
|
1985 |
Jacobs RS, Culver P, Langdon R, O'Brien T, White S. Some pharmacological observations on marine natural products Tetrahedron. 41: 981-984. DOI: 10.1016/S0040-4020(01)96465-8 |
0.32 |
|
1976 |
Shinnick-Gallagher P, Jacobs RS. An analysis of the subsynaptic site of action of theophylline on isolated cat tenuissimus muscle. The Journal of Pharmacology and Experimental Therapeutics. 197: 647-52. PMID 932996 |
0.538 |
|
1971 |
Jacobs RS, Blaber LC. The anti-curare action of sodium fluoride at the neuromuscular junction of cat tenuissimus muscle. Neuropharmacology. 10: 607-12. PMID 4331308 DOI: 10.1016/0028-3908(71)90026-8 |
0.644 |
|
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