Naguib Mechawar, Ph.D. - Publications

Affiliations: 
2007- Psychiatry McGill University Douglas Mental Health University Institute 
Area:
biological psychiatry, glia, neuroanatomy
Website:
https://mgss.ca/naguib-mechawar

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tanti A, Lutz PE, Kim J, O'Leary L, Théroux JF, Turecki G, Mechawar N. Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31374562 DOI: 10.1038/s41386-019-0471-z  1
2019 Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu AP, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Role of D3 dopamine receptors in modulating neuroanatomical changes in response to antipsychotic administration. Scientific Reports. 9: 7850. PMID 31127135 DOI: 10.1038/s41598-019-43955-4  0.76
2019 Pizzagalli DA, Berretta S, Wooten D, Goer F, Pilobello KT, Kumar P, Murray L, Beltzer M, Boyer-Boiteau A, Alpert N, El Fakhri G, Mechawar N, Vitaliano G, Turecki G, Normandin M. Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence. Jama Psychiatry. PMID 31042280 DOI: 10.1001/jamapsychiatry.2019.0801  1
2019 Bell S, Rousseau J, Peng H, Aouabed Z, Priam P, Theroux JF, Jefri M, Tanti A, Wu H, Kolobova I, Silviera H, Manzano-Vargas K, Ehresmann S, Hamdan FF, Hettige N, ... ... Mechawar N, et al. Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. American Journal of Human Genetics. PMID 31031012 DOI: 10.1016/j.ajhg.2019.03.022  1
2019 Salamanca L, Mechawar N, Murai KK, Balling R, Bouvier DS, Skupin A. MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples. Glia. PMID 30983036 DOI: 10.1002/glia.23623  0.32
2019 Xiong W, Cao X, Zeng Y, Qin X, Zhu M, Ren J, Wu Z, Huang Q, Zhang Y, Wang M, Chen L, Turecki G, Mechawar N, Chen W, Yi G, et al. Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30902874 DOI: 10.1523/JNEUROSCI.3069-18.2019  1
2018 Hökfelt T, Barde S, Xu ZD, Kuteeva E, Rüegg J, Le Maitre E, Risling M, Kehr J, Ihnatko R, Theodorsson E, Palkovits M, Deakin W, Bagdy G, Juhasz G, Prud'homme HJ, ... Mechawar N, et al. Neuropeptide and Small Transmitter Coexistence: Fundamental Studies and Relevance to Mental Illness. Frontiers in Neural Circuits. 12: 106. PMID 30627087 DOI: 10.3389/fncir.2018.00106  1
2018 Ehrlich AT, Maroteaux G, Robe A, Venteo L, Nasseef MT, van Kempen LC, Mechawar N, Turecki G, Darcq E, Kieffer BL. Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research. Communications Biology. 1: 102. PMID 30271982 DOI: 10.1038/s42003-018-0106-7  1
2018 Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, ... Mechawar N, et al. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nature Communications. 9: 2459. PMID 29941989 DOI: 10.1038/s41467-018-04883-5  1
2018 Bell S, Maussion G, Jefri M, Peng H, Theroux JF, Silveira H, Soubannier V, Wu H, Hu P, Galat E, Torres-Platas SG, Boudreau-Pinsonneault C, O'Leary LA, Galat V, Turecki G, ... ... Mechawar N, et al. Disruption of GRIN2B Impairs Differentiation in Human Neurons. Stem Cell Reports. PMID 29937144 DOI: 10.1016/j.stemcr.2018.05.018  1
2018 Apazoglou K, Farley S, Gorgievski V, Belzeaux R, Lopez JP, Grenier J, Ibrahim EC, El Khoury MA, Tse YC, Mongredien R, Barbé A, de Macedo CEA, Jaworski W, Bochereau A, Orrico A, ... ... Mechawar N, et al. Antidepressive effects of targeting ELK-1 signal transduction. Nature Medicine. PMID 29736027 DOI: 10.1038/s41591-018-0011-0  1
2018 Guma E, Rocchetti J, Devenyi GA, Tanti A, Mathieu A, Lerch JP, Elgbeili G, Courcot B, Mechawar N, Chakravarty MM, Giros B. Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor. Neuroimage. PMID 29704613 DOI: 10.1016/j.neuroimage.2018.04.054  0.76
2018 Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Mechawar N, et al. Corrigendum: Sex-specific transcriptional signatures in human depression. Nature Medicine. 24: 525. PMID 29634684 DOI: 10.1038/nm0418-525d  1
2018 Poirel O, Mella S, Videau C, Ramet L, Davoli MA, Herzog E, Katsel P, Mechawar N, Haroutunian V, Epelbaum J, Daumas S, El Mestikawy S. Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages. Scientific Reports. 8: 938. PMID 29343737 DOI: 10.1038/s41598-018-19154-y  1
2017 Han S, Yang SH, Kim JY, Mo S, Yang E, Song KM, Ham BJ, Mechawar N, Turecki G, Lee HW, Kim H. Author Correction: Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Scientific Reports. 7: 17090. PMID 29196669 DOI: 10.1038/s41598-017-16991-1  1
2017 Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Mechawar N, et al. Sex-specific transcriptional signatures in human depression. Nature Medicine. PMID 28825715 DOI: 10.1038/nm.4386  1
2017 Lutz PE, Tanti A, Gasecka A, Barnett-Burns S, Kim JJ, Zhou Y, Chen GG, Wakid M, Shaw M, Almeida D, Chay MA, Yang J, Larivière V, M'Boutchou MN, van Kempen LC, ... ... Mechawar N, et al. Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence. The American Journal of Psychiatry. appiajp201716111286. PMID 28750583 DOI: 10.1176/appi.ajp.2017.16111286  1
2017 Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, ... ... Mechawar N, et al. MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications. 8: 15497. PMID 28530238 DOI: 10.1038/ncomms15497  1
2017 Han S, Yang SH, Kim JY, Mo S, Yang E, Song KM, Ham BJ, Mechawar N, Turecki G, Lee HW, Kim H. Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Scientific Reports. 7: 900. PMID 28420875 DOI: 10.1038/s41598-017-01088-6  1
2017 Chen GG, Gross JA, Lutz PE, Vaillancourt K, Maussion G, Bramoulle A, Théroux JF, Gardini ES, Ehlert U, Bourret G, Masurel A, Lepage P, Mechawar N, Turecki G, Ernst C. Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine. Bmc Genomics. 18: 96. PMID 28100169 DOI: 10.1186/s12864-017-3489-9  1
2017 Kelaï S, Ramoz N, Moalic JM, Noble F, Mechawar N, Imbeaud S, Turecki G, Simonneau M, Gorwood P, Maussion G. Netrin G1: its downregulation in the nucleus accumbens of cocaine-conditioned mice and genetic association in human cocaine dependence. Addiction Biology. PMID 28074533 DOI: 10.1111/adb.12485  1
2016 Mahar I, Albuquerque MS, Mondragon-Rodriguez S, Cavanagh C, Davoli MA, Chabot JG, Williams S, Mechawar N, Quirion R, Krantic S. Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer's Disease. Frontiers in Aging Neuroscience. 8: 327. PMID 28154533 DOI: 10.3389/fnagi.2016.00327  1
2016 Barde S, Rüegg J, Prud'homme J, Ekström TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G, Diaz-Heijtz R, Mechawar N, Hökfelt TG. Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940914 DOI: 10.1073/pnas.1617824113  1
2016 Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G. Global and site-specific changes in 5-methylcytosine and 5-hydroxymethylcytosine after extended post-mortem interval. Experimental and Molecular Pathology. PMID 27746278 DOI: 10.1016/j.yexmp.2016.10.004  1
2016 Nagy C, Torres-Platas SG, Mechawar N, Turecki G. Repression of astrocytic connexins in cortical and subcortical brain regions and prefrontal enrichment of H3K9me3 in depression and suicide. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 27516431 DOI: 10.1093/ijnp/pyw071  1
2016 Mahar I, MacIsaac A, Kim JJ, Qiang C, Davoli MA, Turecki G, Mechawar N. Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis. Scientific Reports. 6: 30467. PMID 27469430 DOI: 10.1038/srep30467  1
2016 Gross JA, Nagy C, Lin L, Bonneil É, Maheu M, Thibault P, Mechawar N, Jin P, Turecki G. Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval. Frontiers in Genetics. 7: 120. PMID 27446202 DOI: 10.3389/fgene.2016.00120  1
2016 Huh CY, Amilhon B, Ferguson KA, Manseau F, Torres-Platas SG, Peach JP, Scodras S, Mechawar N, Skinner FK, Williams S. Excitatory Inputs Determine Phase-Locking Strength and Spike-Timing of CA1 Stratum Oriens/Alveus Parvalbumin and Somatostatin Interneurons during Intrinsically Generated Hippocampal Theta Rhythm. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6605-22. PMID 27335395 DOI: 10.1523/JNEUROSCI.3951-13.2016  1
2016 Bouvier DS, Jones EV, Quesseveur G, Davoli MA, A Ferreira T, Quirion R, Mechawar N, Murai KK. High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease. Scientific Reports. 6: 24544. PMID 27090093 DOI: 10.1038/srep24544  1
2016 Isingrini E, Perret L, Rainer Q, Amilhon B, Guma E, Tanti A, Martin G, Robinson J, Moquin L, Marti F, Mechawar N, Williams S, Gratton A, Giros B. Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons. Nature Neuroscience. PMID 26878672 DOI: 10.1038/nn.4245  1
2015 Devorak J, Torres-Platas SG, Davoli MA, Prud'homme J, Turecki G, Mechawar N. Cellular and Molecular Inflammatory Profile of the Choroid Plexus in Depression and Suicide. Frontiers in Psychiatry. 6: 138. PMID 26539126 DOI: 10.3389/fpsyt.2015.00138  1
2015 Lutz PE, Zhou Y, Labbe A, Mechawar N, Turecki G. Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26349406 DOI: 10.1016/j.euroneuro.2015.08.015  1
2015 Maheu ME, Devorak J, Freibauer A, Davoli MA, Turecki G, Mechawar N. Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides. Frontiers in Neuroanatomy. 9: 74. PMID 26082689 DOI: 10.3389/fnana.2015.00074  1
2015 Torres-Platas SG, Nagy C, Wakid M, Turecki G, Mechawar N. Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides. Molecular Psychiatry. PMID 26033239 DOI: 10.1038/mp.2015.65  1
2015 Nagy C, Maheu M, Lopez JP, Vaillancourt K, Cruceanu C, Gross JA, Arnovitz M, Mechawar N, Turecki G. Effects of postmortem interval on biomolecule integrity in the brain. Journal of Neuropathology and Experimental Neurology. 74: 459-69. PMID 25868148 DOI: 10.1097/NEN.0000000000000190  1
2015 Albuquerque MS, Mahar I, Davoli MA, Chabot JG, Mechawar N, Quirion R, Krantic S. Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease. Frontiers in Aging Neuroscience. 7: 30. PMID 25852545 DOI: 10.3389/fnagi.2015.00030  1
2015 Vigneault É, Poirel O, Riad M, Prud'homme J, Dumas S, Turecki G, Fasano C, Mechawar N, El Mestikawy S. Distribution of vesicular glutamate transporters in the human brain. Frontiers in Neuroanatomy. 9: 23. PMID 25798091 DOI: 10.3389/fnana.2015.00023  1
2015 Maheu M, Lopez JP, Crapper L, Davoli MA, Turecki G, Mechawar N. MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression. Translational Psychiatry. 5: e511. PMID 25689572 DOI: 10.1038/tp.2015.11  1
2015 Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy JP, Clark SD, Aghourian M, Bedard MA. Deficit in sustained attention following selective cholinergic lesion of the pedunculopontine tegmental nucleus in rat, as measured with both post-mortem immunocytochemistry and in vivo PET imaging with [¹⁸F]fluoroethoxybenzovesamicol. Behavioural Brain Research. 278: 107-14. PMID 25257103 DOI: 10.1016/j.bbr.2014.09.021  1
2015 Nagy C, Suderman M, Yang J, Szyf M, Mechawar N, Ernst C, Turecki G. Astrocytic abnormalities and global DNA methylation patterns in depression and suicide. Molecular Psychiatry. 20: 320-8. PMID 24662927 DOI: 10.1038/mp.2014.21  1
2014 Pidsley R, Viana J, Hannon E, Spiers H, Troakes C, Al-Saraj S, Mechawar N, Turecki G, Schalkwyk LC, Bray NJ, Mill J. Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biology. 15: 483. PMID 25347937 DOI: 10.1186/s13059-014-0483-2  1
2014 Lopez JP, Lim R, Cruceanu C, Crapper L, Fasano C, Labonte B, Maussion G, Yang JP, Yerko V, Vigneault E, El Mestikawy S, Mechawar N, Pavlidis P, Turecki G. miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. Nature Medicine. 20: 764-8. PMID 24908571 DOI: 10.1038/nm.3582  1
2014 Torres-Platas SG, Cruceanu C, Chen GG, Turecki G, Mechawar N. Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides. Brain, Behavior, and Immunity. 42: 50-9. PMID 24858659 DOI: 10.1016/j.bbi.2014.05.007  1
2014 Maussion G, Yang J, Suderman M, Diallo A, Nagy C, Arnovitz M, Mechawar N, Turecki G. Functional DNA methylation in a transcript specific 3'UTR region of TrkB associates with suicide. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1061-70. PMID 24802768 DOI: 10.4161/epi.29068  1
2014 Torres-Platas SG, Comeau S, Rachalski A, Bo GD, Cruceanu C, Turecki G, Giros B, Mechawar N. Morphometric characterization of microglial phenotypes in human cerebral cortex. Journal of Neuroinflammation. 11: 12. PMID 24447857 DOI: 10.1186/1742-2094-11-12  1
2014 Mahar I, Bambico FR, Mechawar N, Nobrega JN. Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects. Neuroscience and Biobehavioral Reviews. 38: 173-92. PMID 24300695 DOI: 10.1016/j.neubiorev.2013.11.009  1
2014 Cyr M, Parent MJ, Mechawar N, Rosa-Neto P, Soucy JP, Aliaga A, Kostikov A, Maclaren DA, Clark SD, Bedard MA. PET imaging with [¹⁸F]fluoroethoxybenzovesamicol ([¹⁸F]FEOBV) following selective lesion of cholinergic pedunculopontine tegmental neurons in rat. Nuclear Medicine and Biology. 41: 96-101. PMID 24267056 DOI: 10.1016/j.nucmedbio.2013.10.004  1
2014 Lopez JP, Fiori LM, Gross JA, Labonte B, Yerko V, Mechawar N, Turecki G. Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 23-32. PMID 24025154 DOI: 10.1017/S1461145713000941  1
2014 Silva PN, Furuya TK, Braga IL, Rasmussen LT, Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payão SL, Mill J, Smith MC. Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 38: 165-70. PMID 23948933 DOI: 10.3233/JAD-130428  1
2013 Parent MJ, Cyr M, Aliaga A, Kostikov A, Schirrmacher E, Soucy JP, Mechawar N, Rosa-Neto P, Bedard MA. Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry. Ejnmmi Research. 3: 70. PMID 24103360 DOI: 10.1186/2191-219X-3-70  1
2013 Labonté B, Suderman M, Maussion G, Lopez JP, Navarro-Sánchez L, Yerko V, Mechawar N, Szyf M, Meaney MJ, Turecki G. Genome-wide methylation changes in the brains of suicide completers. The American Journal of Psychiatry. 170: 511-20. PMID 23511308 DOI: 10.1176/appi.ajp.2012.12050627  1
2013 Freemantle E, Chen GG, Cruceanu C, Mechawar N, Turecki G. Analysis of oxysterols and cholesterol in prefrontal cortex of suicides. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1241-9. PMID 23369504 DOI: 10.1017/S1461145712001587  1
2013 Morales-Medina JC, Juarez I, Venancio-García E, Cabrera SN, Menard C, Yu W, Flores G, Mechawar N, Quirion R. Impaired structural hippocampal plasticity is associated with emotional and memory deficits in the olfactory bulbectomized rat. Neuroscience. 236: 233-43. PMID 23357118 DOI: 10.1016/j.neuroscience.2013.01.037  1
2013 Maheu ME, Davoli MA, Turecki G, Mechawar N. Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide. Journal of Psychiatric Research. 47: 384-90. PMID 23260340 DOI: 10.1016/j.jpsychires.2012.11.013  1
2013 Freemantle E, Mechawar N, Turecki G. Cholesterol and phospholipids in frontal cortex and synaptosomes of suicide completers: relationship with endosomal lipid trafficking genes. Journal of Psychiatric Research. 47: 272-9. PMID 23164340 DOI: 10.1016/j.jpsychires.2012.10.019  1
2013 Silva PN, Furuya TK, Sampaio Braga I, Rasmussen LT, de Labio RW, Bertolucci PH, Chen ES, Turecki G, Mechawar N, Payão SL, Mill J, Smith MC. CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients. Journal of Alzheimer's Disease : Jad. 33: 349-55. PMID 22954668 DOI: 10.3233/JAD-2012-121192  1
2012 Freemantle E, Lalovic A, Mechawar N, Turecki G. Age and haplotype variations within FADS1 interact and associate with alterations in fatty acid composition in human male cortical brain tissue. Plos One. 7: e42696. PMID 22900039 DOI: 10.1371/journal.pone.0042696  1
2012 Furuya TK, da Silva PN, Payão SL, Rasmussen LT, de Labio RW, Bertolucci PH, Braga IL, Chen ES, Turecki G, Mechawar N, Mill J, de Arruda Cardoso Smith M. SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer's Disease. Neurochemistry International. 61: 973-5. PMID 22836009 DOI: 10.1016/j.neuint.2012.07.014  1
2012 Maussion G, Yang J, Yerko V, Barker P, Mechawar N, Ernst C, Turecki G. Regulation of a truncated form of tropomyosin-related kinase B (TrkB) by Hsa-miR-185* in frontal cortex of suicide completers. Plos One. 7: e39301. PMID 22802923 DOI: 10.1371/journal.pone.0039301  1
2012 Labonté B, Suderman M, Maussion G, Navaro L, Yerko V, Mahar I, Bureau A, Mechawar N, Szyf M, Meaney MJ, Turecki G. Genome-wide epigenetic regulation by early-life trauma. Archives of General Psychiatry. 69: 722-31. PMID 22752237 DOI: 10.1001/archgenpsychiatry.2011.2287  1
2012 Furuya TK, Silva PN, Payão SL, Bertolucci PH, Rasmussen LT, De Labio RW, Braga IL, Chen ES, Turecki G, Mechawar N, Mill J, Smith MA. Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients. Neuroscience. 220: 41-6. PMID 22732502 DOI: 10.1016/j.neuroscience.2012.06.035  1
2012 Mahar I, Bagot RC, Davoli MA, Miksys S, Tyndale RF, Walker CD, Maheu M, Huang SH, Wong TP, Mechawar N. Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeeding. Plos One. 7: e37219. PMID 22615944 DOI: 10.1371/journal.pone.0037219  1
2012 Labonte B, Yerko V, Gross J, Mechawar N, Meaney MJ, Szyf M, Turecki G. Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse. Biological Psychiatry. 72: 41-8. PMID 22444201 DOI: 10.1016/j.biopsych.2012.01.034  1
2012 Krantic S, Isorce N, Mechawar N, Davoli MA, Vignault E, Albuquerque M, Chabot JG, Moyse E, Chauvin JP, Aubert I, McLaurin J, Quirion R. Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model. Journal of Alzheimer's Disease : Jad. 29: 293-308. PMID 22232004 DOI: 10.3233/JAD-2011-110830  1
2012 Turecki G, Ernst C, Jollant F, Labonté B, Mechawar N. The neurodevelopmental origins of suicidal behavior. Trends in Neurosciences. 35: 14-23. PMID 22177979 DOI: 10.1016/j.tins.2011.11.008  1
2011 Mahar I, Tan S, Davoli MA, Dominguez-Lopez S, Qiang C, Rachalski A, Turecki G, Mechawar N. Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects. Plos One. 6: e26610. PMID 22028923 DOI: 10.1371/journal.pone.0026610  1
2011 Yu W, Mechawar N, Krantic S, Quirion R. α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling. Journal of Neurochemistry. 119: 848-58. PMID 21884524 DOI: 10.1111/j.1471-4159.2011.07466.x  1
2011 Torres-Platas SG, Hercher C, Davoli MA, Maussion G, Labonté B, Turecki G, Mechawar N. Astrocytic hypertrophy in anterior cingulate white matter of depressed suicides. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2650-8. PMID 21814185 DOI: 10.1038/npp.2011.154  1
2011 Yu W, Gubkina O, Mechawar N, Elwell D, Quirion R, Krantic S. Expression of apoptosis-inducing factor (AIF) in the aged rat brain. Neurobiology of Aging. 32: 179-80. PMID 19251341 DOI: 10.1016/j.neurobiolaging.2009.01.010  1
2010 Rousseau J, Klinger S, Rachalski A, Turgeon B, Déléris P, Vigneault E, Poirier-Héon JF, Davoli MA, Mechawar N, El Mestikawy S, Cermakian N, Meloche S. Targeted inactivation of Mapk4 in mice reveals specific nonredundant functions of Erk3/Erk4 subfamily mitogen-activated protein kinases. Molecular and Cellular Biology. 30: 5752-63. PMID 20956558 DOI: 10.1128/MCB.01147-10  1
2010 Yu W, Mechawar N, Krantic S, Quirion R. Evidence for the involvement of apoptosis-inducing factor-mediated caspase-independent neuronal death in Alzheimer disease. The American Journal of Pathology. 176: 2209-18. PMID 20228227 DOI: 10.2353/ajpath.2010.090496  1
2010 Chen GG, Fiori LM, Moquin L, Gratton A, Mamer O, Mechawar N, Turecki G. Evidence of altered polyamine concentrations in cerebral cortex of suicide completers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1477-84. PMID 20200507 DOI: 10.1038/npp.2010.17  1
2010 Hercher C, Canetti L, Turecki G, Mechawar N. Anterior cingulate pyramidal neurons display altered dendritic branching in depressed suicides. Journal of Psychiatric Research. 44: 286-93. PMID 19765721 DOI: 10.1016/j.jpsychires.2009.08.011  1
2009 Ernst C, Mechawar N, Turecki G. Suicide neurobiology. Progress in Neurobiology. 89: 315-33. PMID 19766697 DOI: 10.1016/j.pneurobio.2009.09.001  1
2009 Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. Plos One. 4: e6585. PMID 19668376 DOI: 10.1371/journal.pone.0006585  1
2009 Hercher C, Parent M, Flores C, Canetti L, Turecki G, Mechawar N. Alcohol dependence-related increase of glial cell density in the anterior cingulate cortex of suicide completers. Journal of Psychiatry & Neuroscience : Jpn. 34: 281-8. PMID 19568479  1
2009 Fiori LM, Mechawar N, Turecki G. Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completers. Biological Psychiatry. 66: 460-7. PMID 19446796 DOI: 10.1016/j.biopsych.2009.04.002  1
2009 Hercher C, Turecki G, Mechawar N. Through the looking glass: examining neuroanatomical evidence for cellular alterations in major depression. Journal of Psychiatric Research. 43: 947-61. PMID 19233384 DOI: 10.1016/j.jpsychires.2009.01.006  1
2007 Mechawar N, Lacoste B, Yu WF, Srivastava LK, Quirion R. Developmental profile of neuregulin receptor ErbB4 in postnatal rat cerebral cortex and hippocampus. Neuroscience. 148: 126-39. PMID 17630218 DOI: 10.1016/j.neuroscience.2007.04.066  1
2007 Moser N, Mechawar N, Jones I, Gochberg-Sarver A, Orr-Urtreger A, Plomann M, Salas R, Molles B, Marubio L, Roth U, Maskos U, Winzer-Serhan U, Bourgeois JP, Le Sourd AM, De Biasi M, et al. Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures. Journal of Neurochemistry. 102: 479-92. PMID 17419810 DOI: 10.1111/j.1471-4159.2007.04498.x  1
2007 Krantic S, Mechawar N, Reix S, Quirion R. Apoptosis-inducing factor: a matter of neuron life and death. Progress in Neurobiology. 81: 179-96. PMID 17267093 DOI: 10.1016/j.pneurobio.2006.12.002  1
2007 Reix S, Mechawar N, Susin SA, Quirion R, Krantic S. Expression of cortical and hippocampal apoptosis-inducing factor (AIF) in aging and Alzheimer's disease. Neurobiology of Aging. 28: 351-6. PMID 16504343 DOI: 10.1016/j.neurobiolaging.2006.01.003  1
2005 Krantic S, Mechawar N, Reix S, Quirion R. Molecular basis of programmed cell death involved in neurodegeneration. Trends in Neurosciences. 28: 670-6. PMID 16216345 DOI: 10.1016/j.tins.2005.09.011  1
2004 Mechawar N, Saghatelyan A, Grailhe R, Scoriels L, Gheusi G, Gabellec MM, Lledo PM, Changeux JP. Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proceedings of the National Academy of Sciences of the United States of America. 101: 9822-6. PMID 15210938 DOI: 10.1073/pnas.0403361101  1
2004 Descarries L, Mechawar N, Aznavour N, Watkins KC. Structural determinants of the roles of acetylcholine in cerebral cortex. Progress in Brain Research. 145: 45-58. PMID 14650905 DOI: 10.1016/S0079-6123(03)45002-4  1
2003 Aznavour N, Mechawar N, Watkins KC, Descarries L. Fine structural features of the acetylcholine innervation in the developing neostriatum of rat. The Journal of Comparative Neurology. 460: 280-91. PMID 12687691 DOI: 10.1002/cne.10660  1
2002 Aznavour N, Mechawar N, Descarries L. Comparative analysis of cholinergic innervation in the dorsal hippocampus of adult mouse and rat: a quantitative immunocytochemical study. Hippocampus. 12: 206-17. PMID 12000119 DOI: 10.1002/hipo.1108  1
2002 Pierret P, Mechawar N, Vallée A, Patel J, Priestley JV, Dunn RJ, Dower NA, Stone JC, Richardson PM. Presence of Ras guanyl nucleotide-releasing protein in striosomes of the mature and developing rat. Neuroscience. 111: 83-94. PMID 11955714 DOI: 10.1016/S0306-4522(01)00597-8  1
2002 Mechawar N, Watkins KC, Descarries L. Ultrastructural features of the acetylcholine innervation in the developing parietal cortex of rat. The Journal of Comparative Neurology. 443: 250-8. PMID 11807835 DOI: 10.1002/cne.10114  1
2001 Mechawar N, Descarries L. The cholinergic innervation develops early and rapidly in the rat cerebral cortex: a quantitative immunocytochemical study. Neuroscience. 108: 555-67. PMID 11738494 DOI: 10.1016/S0306-4522(01)00389-X  1
2001 Pierret P, Vallée A, Mechawar N, Dower NA, Stone JC, Richardson PM, Dunn RJ. Cellular and subcellular localization of Ras guanyl nucleotide-releasing protein in the rat hippocampus. Neuroscience. 108: 381-90. PMID 11738253 DOI: 10.1016/S0306-4522(01)00429-8  1
2000 Descarries L, Mechawar N. Ultrastructural evidence for diffuse transmission by monoamine and acetylcholine neurons of the central nervous system. Progress in Brain Research. 125: 27-47. PMID 11098652 DOI: 10.1016/S0079-6123(00)25005-X  1
2000 Mechawar N, Cozzari C, Descarries L. Cholinergic innervation in adult rat cerebral cortex: a quantitative immunocytochemical description. The Journal of Comparative Neurology. 428: 305-18. PMID 11064369 DOI: 10.1002/1096-9861(20001211)428:2<305::AID-CNE9>3.0.CO;2-Y  1
1998 Mansour-Robaey S, Mechawar N, Radja F, Beaulieu C, Descarries L. Quantified distribution of serotonin transporter and receptors during the postnatal development of the rat barrel field cortex. Brain Research. Developmental Brain Research. 107: 159-63. PMID 9602106 DOI: 10.1016/S0165-3806(98)00016-9  1
1997 Mechawar N, Anctil M. Melatonin in a primitive metazoan: seasonal changes of levels and immunohistochemical visualization in neurons. The Journal of Comparative Neurology. 387: 243-54. PMID 9336226 DOI: 10.1002/(SICI)1096-9861(19971020)387:2<243::AID-CNE6>3.0.CO;2-0  1
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