| Year |
Citation |
Score |
| 2022 |
Disney A, Olson KM, Shafer AM, Moore SC, Anand JP, Traynor JR, Husbands SM. Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose. Acs Chemical Neuroscience. PMID 36223082 DOI: 10.1021/acschemneuro.2c00464 |
0.839 |
|
| 2020 |
Henry S, Anand JP, Brinkel AC, McMillan DM, Twarozynski JJ, Loo CE, Traynor JR, Mosberg HI. SAR Matrices Enable Discovery of Mixed Efficacy μ-Opioid Receptor Agonist Peptidomimetics with Simplified Structures through an Aromatic-Amine Pharmacophore. Acs Chemical Neuroscience. PMID 33346631 DOI: 10.1021/acschemneuro.0c00693 |
0.871 |
|
| 2020 |
Hassanien SH, Bassman JR, Perrien Naccarato CM, Twarozynski JJ, Traynor JR, Iula DM, Anand JP. In vitro Pharmacology of Fentanyl Analogs at the Human Mu Opioid Receptor and Their Spectroscopic Analysis. Drug Testing and Analysis. PMID 32415719 DOI: 10.1002/Dta.2822 |
0.833 |
|
| 2020 |
Henry S, Anand JP, Twarozynski JJ, Brinkel AC, Pogozheva ID, Sears BF, Jutkiewicz EM, Traynor JR, Mosberg HI. Aromatic-Amine Pendants Produce Highly Potent and Efficacious Mixed Efficacy Mu-Opioid Receptor (MOR)/Delta-Opioid Receptor (DOR) Peptidomimetics with Enhanced Metabolic Stability. Journal of Medicinal Chemistry. PMID 31986033 DOI: 10.1021/Acs.Jmedchem.9B01818 |
0.886 |
|
| 2019 |
Montgomery D, Anand JP, Baber MA, Twarozynski JJ, Hartman JG, Delong LJ, Traynor JR, Mosberg HI. Structure-Activity Relationships of 7-Substituted Dimethyltyrosine-Tetrahydroisoquinoline Opioid Peptidomimetics. Molecules (Basel, Switzerland). 24. PMID 31779072 DOI: 10.3390/Molecules24234302 |
0.9 |
|
| 2019 |
Montgomery D, Anand JP, Griggs N, Fernandez TJ, Hartman JG, Sanchez-Santiago AA, Pogozheva ID, Traynor JR, Mosberg HI. Novel Dimethyltyrosine-Tetrahydroisoquinoline Peptidomimetics with Aromatic Tetrahydroisoquinoline Substitutions Show In Vitro Kappa and Mu Opioid Receptor Agonism. Acs Chemical Neuroscience. PMID 31199621 DOI: 10.1021/Acschemneuro.9B00250 |
0.886 |
|
| 2019 |
Henry S, Fernandez TM, Anand JP, Griggs N, Traynor JR, Mosberg HI. Structural Simplification of a Tetrahydroquinoline Core Peptidomimetic µ-Opioid-Receptor (MOR) Agonist/ δ-Opioid Receptor (DOR) Antagonist Produces Improved Metabolic Stability . Journal of Medicinal Chemistry. PMID 30924650 DOI: 10.1021/Acs.Jmedchem.9B00219 |
0.876 |
|
| 2019 |
Nastase AF, Anand JP, Bender AM, Montgomery D, Griggs N, Fernandez TJ, Jutkiewicz EM, Traynor JR, Mosberg HI. Dual Pharmacophores Explored via Structure-Activity Relationship (SAR) Matrix: Insights into Potent, Bifunctional Opioid Ligand Design. Journal of Medicinal Chemistry. PMID 30916966 DOI: 10.1021/Acs.Jmedchem.9B00378 |
0.875 |
|
| 2018 |
Nastase AF, Griggs NW, Anand JP, Fernandez TJ, Harland AA, Trask TJ, Jutkiewicz EM, Traynor JR, Mosberg HI. Synthesis and pharmacological evaluation of novel C-8 substituted tetrahydroquinolines as balanced-affinity mu/delta opioid ligands for the treatment of pain. Acs Chemical Neuroscience. PMID 29677442 DOI: 10.1021/Acschemneuro.8B00139 |
0.872 |
|
| 2018 |
Anand JP, Montgomery D. Multifunctional Opioid Ligands. Handbook of Experimental Pharmacology. PMID 29675582 DOI: 10.1007/164_2018_104 |
0.83 |
|
| 2018 |
Anand JP, Kochan KE, Nastase AF, Montgomery D, Griggs NW, Traynor JR, Mosberg HI, Jutkiewicz EM. In Vivo Effects of μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Peptidomimetics Following Acute and Repeated Administration. British Journal of Pharmacology. PMID 29352503 DOI: 10.1111/Bph.14148 |
0.883 |
|
| 2016 |
Harland AA, Bender AM, Griggs NW, Gao C, Anand JP, Pogozheva ID, Traynor JR, Jutkiewicz EM, Mosberg HI. Effects of N-Substitutions on the Tetrahydroquinoline (THQ) core of Mixed-Efficacy μ-Opioid Receptor (MOR)/ δ-Opioid Receptor (DOR) Ligands. Journal of Medicinal Chemistry. PMID 27148755 DOI: 10.1021/Acs.Jmedchem.6B00308 |
0.882 |
|
| 2016 |
Anand JP, Boyer BT, Mosberg HI, Jutkiewicz EM. The behavioral effects of a mixed efficacy antinociceptive peptide, VRP26, following chronic administration in mice. Psychopharmacology. PMID 27117141 DOI: 10.1007/S00213-016-4296-8 |
0.828 |
|
| 2015 |
Harland AA, Yeomans L, Griggs NW, Anand JP, Pogozheva ID, Jutkiewicz EM, Traynor JR, Mosberg HI. Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/ δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities. Journal of Medicinal Chemistry. PMID 26524472 DOI: 10.1021/Acs.Jmedchem.5B01270 |
0.887 |
|
| 2015 |
Bender AM, Griggs NW, Anand JP, Traynor JR, Jutkiewicz EM, Mosberg HI. Asymmetric Synthesis and in Vitro and in Vivo Activity of Tetrahydroquinolines Featuring a Diverse Set of Polar Substitutions at the 6 Position as Mixed-Efficacy μ Opioid Receptor/δ Opioid Receptor Ligands. Acs Chemical Neuroscience. 6: 1428-35. PMID 25938166 DOI: 10.1021/Acschemneuro.5B00100 |
0.878 |
|
| 2014 |
Mosberg HI, Yeomans L, Anand JP, Porter V, Sobczyk-Kojiro K, Traynor JR, Jutkiewicz EM. Development of a bioavailable μ opioid receptor (MOPr) agonist, δ opioid receptor (DOPr) antagonist peptide that evokes antinociception without development of acute tolerance. Journal of Medicinal Chemistry. 57: 3148-53. PMID 24641190 DOI: 10.1021/Jm5002088 |
0.866 |
|
| 2014 |
Anand JP, Porter-Barrus VR, Waldschmidt HV, Yeomans L, Pogozheva ID, Traynor JR, Mosberg HI. Translation of structure-activity relationships from cyclic mixed efficacy opioid peptides to linear analogues. Biopolymers. 102: 107-14. PMID 24436042 DOI: 10.1002/Bip.22437 |
0.88 |
|
| 2013 |
Mosberg HI, Yeomans L, Harland AA, Bender AM, Sobczyk-Kojiro K, Anand JP, Clark MJ, Jutkiewicz EM, Traynor JR. Opioid peptidomimetics: leads for the design of bioavailable mixed efficacy μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands. Journal of Medicinal Chemistry. 56: 2139-49. PMID 23419026 DOI: 10.1021/Jm400050Y |
0.9 |
|
| 2012 |
Anand JP, Purington LC, Pogozheva ID, Traynor JR, Mosberg HI. Modulation of opioid receptor ligand affinity and efficacy using active and inactive state receptor models. Chemical Biology & Drug Design. 80: 763-70. PMID 22882801 DOI: 10.1111/Cbdd.12014 |
0.852 |
|
| 2009 |
Kuszak AJ, Pitchiaya S, Anand JP, Mosberg HI, Walter NG, Sunahara RK. Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2. The Journal of Biological Chemistry. 284: 26732-41. PMID 19542234 DOI: 10.1074/Jbc.M109.026922 |
0.704 |
|
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