Ken A. Witt, Ph.D. - Publications

Affiliations: 
University of Arizona, Tucson, AZ 
Area:
blood-brain barrier, drug delivery

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Reeb C, Sandoval K, Wooten J, Harris M, Schaller M, House A, Witt KA. Dietary Dependent Alteration of Blood‐Brain Barrier Tight Junctional Protein Expression The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05849  0.304
2019 Sandoval K, Umbaugh D, House A, Crider A, Witt K. Somatostatin Receptor Subtype-4 Regulates mRNA Expression of Amyloid-Beta Degrading Enzymes and Microglia Mediators of Phagocytosis in Brains of 3xTg-AD Mice. Neurochemical Research. PMID 31630317 DOI: 10.1007/S11064-019-02890-6  0.335
2014 Witt KA, Sandoval KE. Steroids and the blood-brain barrier: therapeutic implications. Advances in Pharmacology (San Diego, Calif.). 71: 361-90. PMID 25307223 DOI: 10.1016/Bs.Apha.2014.06.018  0.441
2013 Sandoval KE, Farr SA, Banks WA, Crider AM, Morley JE, Witt KA. Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ(42) oligomers via a metalloproteinase-dependent mechanism. Brain Research. 1520: 145-56. PMID 23669069 DOI: 10.1016/J.Brainres.2013.05.006  0.356
2013 Egleton RD, Witt KA, Davis TP. Opioid Peptides Handbook of Biologically Active Peptides. 1696-1701. DOI: 10.1016/B978-0-12-385095-9.00232-3  0.672
2012 Sandoval KE, Farr SA, Banks WA, Crider AM, Morley JE, Witt KA. Somatostatin receptor subtype-4 agonist NNC 26-9100 decreases extracellular and intracellular Aβ₁₋₄₂ trimers. European Journal of Pharmacology. 683: 116-24. PMID 22449380 DOI: 10.1016/J.Ejphar.2012.03.020  0.345
2011 Sandoval KE, Witt KA. Age and 17β-estradiol effects on blood-brain barrier tight junction and estrogen receptor proteins in ovariectomized rats. Microvascular Research. 81: 198-205. PMID 21192956 DOI: 10.1016/J.Mvr.2010.12.007  0.345
2011 Sandoval KE, Farr SA, Banks WA, Niehoff ML, Morley JE, Crider AM, Witt KA. Chronic peripheral administration of somatostatin receptor subtype-4 agonist NNC 26-9100 enhances learning and memory in SAMP8 mice. European Journal of Pharmacology. 654: 53-9. PMID 21185826 DOI: 10.1016/J.Ejphar.2010.12.013  0.352
2010 Witt KA, Ronaldson PT, Sandoval KE, Davis TP. CNS delivery of peptides across the bbb using the dual-artery in situ brain perfusion model Neuromethods. 45: 233-247. DOI: 10.1007/978-1-60761-529-3_11  0.717
2008 Sandoval KE, Witt KA. Blood-brain barrier tight junction permeability and ischemic stroke. Neurobiology of Disease. 32: 200-19. PMID 18790057 DOI: 10.1016/J.Nbd.2008.08.005  0.399
2008 Witt KA, Mark KS, Sandoval KE, Davis TP. Reoxygenation stress on blood-brain barrier paracellular permeability and edema in the rat. Microvascular Research. 75: 91-6. PMID 17651765 DOI: 10.1016/J.Mvr.2007.06.004  0.748
2006 Witt KA, Davis TP. CNS drug delivery: opioid peptides and the blood-brain barrier. The Aaps Journal. 8: E76-88. PMID 16584136 DOI: 10.1208/Aapsj080109  0.54
2006 Sandoval KE, Umbaugh DS, Witt KA. P2-051: INCREASED BRAIN MRNA EXPRESSION OF BETA AMYLOID DEGRADING ENZYMES WITH SOMATOSTATIN-4 RECEPTOR AGONIST TREATMENT IN 3XTG MICE Alzheimer's & Dementia. 14: P686-P686. DOI: 10.1016/J.Jalz.2018.06.736  0.356
2006 Egleton RD, Witt KA, Davis TP. Opiate Peptides And The Blood-Brain Barrier Handbook of Biologically Active Peptides. 1429-1434. DOI: 10.1016/B978-012369442-3/50202-6  0.739
2005 Witt KA, Mark KS, Huber J, Davis TP. Hypoxia-inducible factor and nuclear factor kappa-B activation in blood-brain barrier endothelium under hypoxic/reoxygenation stress. Journal of Neurochemistry. 92: 203-14. PMID 15606909 DOI: 10.1111/J.1471-4159.2004.02871.X  0.738
2003 Witt KA, Mark KS, Hom S, Davis TP. Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2820-31. PMID 12907427 DOI: 10.1152/Ajpheart.00589.2003  0.761
2003 Huber JD, Campos CR, Egleton RD, Witt K, Guo L, Roberts MJ, Bentley MD, Davis TP. Conjugation of low molecular weight poly(ethylene glycol) to biphalin enhances antinociceptive profile. Journal of Pharmaceutical Sciences. 92: 1377-85. PMID 12820142 DOI: 10.1002/Jps.10406  0.725
2003 Egleton RD, Witt KA, Davis TP. Peptides and the Blood-Brain Barrier: Enhancing Peptide Bioavailability to the Brain Blood-Spinal Cord and Brain Barriers in Health and Disease. 107-115. DOI: 10.1016/B978-012639011-7/50015-2  0.735
2002 Witt KA, Huber JD, Egleton RD, Davis TP. Pluronic p85 block copolymer enhances opioid peptide analgesia. The Journal of Pharmacology and Experimental Therapeutics. 303: 760-7. PMID 12388663 DOI: 10.1124/Jpet.102.039545  0.698
2001 Witt KA, Gillespie TJ, Huber JD, Egleton RD, Davis TP. Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability. Peptides. 22: 2329-43. PMID 11786210 DOI: 10.1016/S0196-9781(01)00537-X  0.733
2001 Witt KA, Huber JD, Egleton RD, Roberts MJ, Bentley MD, Guo L, Wei H, Yamamura HI, Davis TP. Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE). The Journal of Pharmacology and Experimental Therapeutics. 298: 848-56. PMID 11454951  0.718
2001 Huber JD, Witt KA, Hom S, Egleton RD, Mark KS, Davis TP. Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1241-8. PMID 11179069 DOI: 10.1152/Ajpheart.2001.280.3.H1241  0.708
2000 Witt KA, Huber JD, Egleton RD, Davis TP. Insulin enhancement of opioid peptide transport across the blood-brain barrier and assessment of analgesic effect. The Journal of Pharmacology and Experimental Therapeutics. 295: 972-8. PMID 11082431  0.699
2000 Witt KA, Slate CA, Egleton RD, Huber JD, Yamamura HI, Hruby VJ, Davis TP. Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin. Journal of Neurochemistry. 75: 424-35. PMID 10854288 DOI: 10.1046/J.1471-4159.2000.0750424.X  0.707
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