Alexander R. McCampbell, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 

15/33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Staropoli JF, Li H, Chun SJ, Allaire N, Cullen P, Thai A, Fleet CM, Hua Y, Bennett CF, Krainer AR, Kerr D, McCampbell A, Rigo F, Carulli JP. Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7. Genomics. 105: 220-8. PMID 25645699 DOI: 10.1016/J.Ygeno.2015.01.007  0.4
2014 Converso A, Hartingh T, Fraley ME, Garbaccio RM, Hartman GD, Huang SY, Majercak JM, McCampbell A, Na SJ, Ray WJ, Savage MJ, Wolffe C, Yeh S, Yu Y, White R, et al. Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. Bioorganic & Medicinal Chemistry Letters. 24: 2737-40. PMID 24813734 DOI: 10.1016/J.Bmcl.2014.04.034  0.4
2014 Savage MJ, Kalinina J, Wolfe A, Tugusheva K, Korn R, Cash-Mason T, Maxwell JW, Hatcher NG, Haugabook SJ, Wu G, Howell BJ, Renger JJ, Shughrue PJ, McCampbell A. A sensitive aβ oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2884-97. PMID 24553930 DOI: 10.1523/Jneurosci.1675-13.2014  0.4
2011 Zhao WQ, Toolan D, Hepler RW, Wolfe AL, Yu Y, Price E, Uebele VN, Schachter JB, Reynolds IJ, Renger JJ, McCampbell A, Ray WJ. High throughput monitoring of amyloid-β(42) assembly into soluble oligomers achieved by sensitive conformation state-dependent immunoassays. Journal of Alzheimer's Disease : Jad. 25: 655-69. PMID 21483096 DOI: 10.3233/Jad-2011-102022  0.4
2011 McCampbell A, Wessner K, Marlatt MW, Wolffe C, Toolan D, Podtelezhnikov A, Yeh S, Zhang R, Szczerba P, Tanis KQ, Majercak J, Ray WJ, Savage M. Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine. Journal of Neurochemistry. 116: 82-92. PMID 21054384 DOI: 10.1111/J.1471-4159.2010.07087.X  0.4
2009 Eichler FS, Hornemann T, McCampbell A, Kuljis D, Penno A, Vardeh D, Tamrazian E, Garofalo K, Lee HJ, Kini L, Selig M, Frosch M, Gable K, von Eckardstein A, Woolf CJ, et al. Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14646-51. PMID 19923297 DOI: 10.1523/Jneurosci.2536-09.2009  0.4
2009 Ma L, Seager MA, Seager M, Wittmann M, Jacobson M, Bickel D, Burno M, Jones K, Graufelds VK, Xu G, Pearson M, McCampbell A, Gaspar R, Shughrue P, Danziger A, et al. Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation. Proceedings of the National Academy of Sciences of the United States of America. 106: 15950-5. PMID 19717450 DOI: 10.1073/Pnas.0900903106  0.4
2005 McCampbell A, Truong D, Broom DC, Allchorne A, Gable K, Cutler RG, Mattson MP, Woolf CJ, Frosch MP, Harmon JM, Dunn TM, Brown RH. Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. Human Molecular Genetics. 14: 3507-21. PMID 16210380 DOI: 10.1093/Hmg/Ddi380  0.4
2001 McCampbell A, Taye AA, Whitty L, Penney E, Steffan JS, Fischbeck KH. Histone deacetylase inhibitors reduce polyglutamine toxicity. Proceedings of the National Academy of Sciences of the United States of America. 98: 15179-84. PMID 11742087 DOI: 10.1073/Pnas.261400698  0.4
2001 Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 413: 739-43. PMID 11607033 DOI: 10.1038/35099568  0.4
2001 McCampbell A, Fischbeck KH. Polyglutamine and CBP: fatal attraction? Nature Medicine. 7: 528-30. PMID 11329046 DOI: 10.1038/87842  0.4
2000 McCampbell A, Taylor JP, Taye AA, Robitschek J, Li M, Walcott J, Merry D, Chai Y, Paulson H, Sobue G, Fischbeck KH. CREB-binding protein sequestration by expanded polyglutamine. Human Molecular Genetics. 9: 2197-202. PMID 10958659 DOI: 10.1093/Hmg/9.14.2197  0.4
1997 Dornan WA, McCampbell AR, Tinkler GP, Hickman LJ, Bannon AW, Decker MW, Gunther KL. Comparison of site specific injections into the basal forebrain on water maze and radial arm maze performance in the male rat after immunolesioning with 192 IgG saporin. Behavioural Brain Research. 86: 181-9. PMID 9134153 DOI: 10.1016/S0166-4328(96)02264-4  0.4
1996 Dornan WA, McCampbell AR, Tinkler GP, Hickman LJ, Bannon AW, Decker MW, Gunther KL. Comparison of site-specific injections into the basal forebrain on water maze and radial arm maze performance in the male rat after immunolesioning with 192 IgG saporin. Behavioural Brain Research. 82: 93-101. PMID 9021074 DOI: 10.1016/S0166-4328(97)81112-6  0.4
1993 Dornan WA, Kang DE, McCampbell A, Kang EE. Bilateral injections of βA(25-35)+ IBO into the hippocampus disrupts acquisition of spatial learning in the rat Neuroreport. 5: 165-168. PMID 8111004 DOI: 10.1097/00001756-199311180-00018  0.4
Low-probability matches
2021 Fumagalli L, Young FL, Boeynaems S, De Decker M, Mehta AR, Swijsen A, Fazal R, Guo W, Moisse M, Beckers J, Dedeene L, Selvaraj BT, Vandoorne T, Madan V, van Blitterswijk M, ... ... McCampbell A, et al. -derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science Advances. 7. PMID 33837088 DOI: 10.1126/sciadv.abg3013  0.01
2021 Torregrosa T, Lehman S, Hana S, Marsh G, Xu S, Koszka K, Mastrangelo N, McCampbell A, Henderson CE, Lo SC. Use of CRISPR/Cas9-mediated disruption of CNS cell type genes to profile transduction of AAV by neonatal intracerebroventricular delivery in mice. Gene Therapy. PMID 33612827 DOI: 10.1038/s41434-021-00223-3  0.01
2020 Cook CN, Wu Y, Odeh HM, Gendron TF, Jansen-West K, Del Rosso G, Yue M, Jiang P, Gomes E, Tong J, Daughrity LM, Avendano NM, Castanedes-Casey M, Shao W, Oskarsson B, ... ... McCampbell A, et al. poly(GR) aggregation induces TDP-43 proteinopathy. Science Translational Medicine. 12. PMID 32878979 DOI: 10.1126/Scitranslmed.Abb3774  0.01
2020 Kankel MW, Sen A, Lu L, Theodorou M, Dimlich DN, McCampbell A, Henderson CE, Shneider NA, Artavanis-Tsakonas S. Amyotrophic Lateral Sclerosis Modifiers in Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Genetics. PMID 32345615 DOI: 10.1534/Genetics.119.302985  0.01
2019 Chen Y, Mazur C, Luo Y, Sun L, Zhang M, McCampbell A, Tomassy GS. Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System. Journal of Visualized Experiments : Jove. PMID 31736489 DOI: 10.3791/60274  0.01
2019 Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, ... ... McCampbell A, et al. Heterochromatin anomalies and double-stranded RNA accumulation underlie poly(PR) toxicity. Science (New York, N.Y.). 363. PMID 30765536 DOI: 10.1126/Science.Aav2606  0.01
2018 McCampbell A, Cole T, Wegener AJ, Tomassy GS, Setnicka A, Farley BJ, Schoch KM, Hoye ML, Shabsovich M, Sun L, Luo Y, Zhang M, Thankamony S, Salzman DW, Cudkowicz M, et al. Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models. The Journal of Clinical Investigation. PMID 30010620 DOI: 10.1172/Jci99081  0.01
2018 Selvaraj BT, Livesey MR, Zhao C, Gregory JM, James OT, Cleary EM, Chouhan AK, Gane AB, Perkins EM, Dando O, Lillico SG, Lee YB, Nishimura AL, Poreci U, Thankamony S, ... ... McCampbell A, et al. C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity. Nature Communications. 9: 347. PMID 29367641 DOI: 10.1038/S41467-017-02729-0  0.01
2017 Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, ... ... McCampbell A, et al. Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28356511 DOI: 10.1126/Scitranslmed.Aai7866  0.01
2017 Sweeney P, Park H, Baumann M, Dunlop J, Frydman J, Kopito R, McCampbell A, Leblanc G, Venkateswaran A, Nurmi A, Hodgson R. Protein misfolding in neurodegenerative diseases: implications and strategies. Translational Neurodegeneration. 6: 6. PMID 28293421 DOI: 10.1186/S40035-017-0077-5  0.01
2015 Periz G, Lu J, Zhang T, Kankel MW, Jablonski AM, Kalb R, McCampbell A, Wang J. Regulation of protein quality control by UBE4B and LSD1 through p53-mediated transcription. Plos Biology. 13: e1002114. PMID 25837623 DOI: 10.1371/Journal.Pbio.1002114  0.01
2012 Wolfe A, McCampbell A, Hatcher N, Tugusheva K, Haugabook S, Maxwell J, Wu G, Howell B, Renger J, Shughrue P, Savage M. P2-043: A quantitative assay selective for amyloid oligomer species differentiates cerebrospinal fluid from Alzheimer's disease and age-matched normal Alzheimer's & Dementia. 8: P278-P278. DOI: 10.1016/j.jalz.2012.05.746  0.01
2011 McCampbell A, Michener M, Smith B, Lennox C, Dancho M, Yeh S, Zhang R, Rajapaske H, Ray W, Reynolds I, Kornilova A. Peripheral and central responses of kynurenine pathway in response to low and high tryptophan-containing food in rhesus macaques Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.323  0.01
2010 McCampbell A, Wessner K, Toolan D, Podtelezhnikov A, Majercak J, Tanis KQ, Ray WJ, Savage MJ. High methionine diet induces beta-amyloid–related transcriptional changes in mouse brain Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.669  0.01
2010 Savage MJ, Wu G, McCampbell A, Wessner KR, Citron M, Liang X, Hsieh S, Wolfe AL, Kinney GG, Rosen LB, Renger JJ. O3-07-03: A novel multivalent Abeta peptide vaccine with preclinical evidence of a central immune response that generates antisera recognizing a wide range of Abeta peptide species Alzheimer's & Dementia. 6: S142-S142. DOI: 10.1016/j.jalz.2010.05.437  0.01
2008 McCampbell A, Seager M, Zerbinatti C, Nunes I, Savage MJ, Meziane H, Rosahl T. P1-037: Presence of an anxiety phenotype in APOE-KO and YAC-APP/APOE-KO mice Alzheimer's & Dementia. 4: T216-T216. DOI: 10.1016/j.jalz.2008.05.622  0.01
2008 Savage MJ, McCampbell AR, Wessner K, Na S, Marlatt M, Bickel D, Burno M, Jones K, Kuzmick-Graufelds V, Yeh S, Zhang R, White R, Seager M, Majercak J, Ray WJ. P1-016: Dietary induction of hyperhomocystemia and the impact on Alzheimer's disease-relevant markers Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.601  0.01
2005 Dionne A, Brunet D, McCampbell A, Dupré N. Adrenomyeloneuropathy: report of a new mutation in a French Canadian female. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 32: 261-3. PMID 16018167 DOI: 10.1017/S0317167100004091  0.01
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