Year |
Citation |
Score |
1999 |
Yuann JM, Liu KJ, Hamilton JW, Wetterhahn KE. In vivo effects of ascorbate and glutathione on the uptake of chromium, formation of chromium(V), chromium-DNA binding and 8-hydroxy-2'-deoxyguanosine in liver and kidney of osteogenic disorder shionogi rats following treatment with chromium(VI). Carcinogenesis. 20: 1267-75. PMID 10383900 DOI: 10.1093/Carcin/20.7.1267 |
0.523 |
|
1997 |
Wilker JJ, Wetterhahn KE, Lippard SJ. Methyl Transfer to Mercury Thiolates: Effects of Coordination Number and Ligand Dissociation. Inorganic Chemistry. 36: 2079-2083. PMID 11669826 DOI: 10.1021/Ic961178I |
0.501 |
|
1997 |
Sugden KD, Wetterhahn KE. Direct and hydrogen peroxide-induced chromium(V) oxidation of deoxyribose in single-stranded and double-stranded calf thymus DNA Chemical Research in Toxicology. 10: 1397-1406. PMID 9437531 DOI: 10.1021/tx970135r |
0.317 |
|
1996 |
Costa M, Zhitkovich A, Gargas M, Paustenbach D, Finley B, Kuykendall J, Billings R, Carlson TJ, Wetterhahn K, Xu J, Patierno S, Bogdanffy M. Interlaboratory validation of a new assay for DNA-protein crosslinks. Mutation Research. 369: 13-21. PMID 8700178 DOI: 10.1016/S0165-1218(96)90043-9 |
0.385 |
|
1995 |
Stearns DM, Kennedy LJ, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro. Biochemistry. 34: 910-9. PMID 7827049 DOI: 10.1021/Bi00003A025 |
0.352 |
|
1994 |
Alcedo JA, Misra M, Hamilton JW, Wetterhahn KE. The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metallothionein gene in vivo. Carcinogenesis. 15: 1089-92. PMID 8200074 DOI: 10.1093/Carcin/15.5.1089 |
0.543 |
|
1994 |
Misra M, Alcedo JA, Wetterhahn KE. Two pathways for chromium(VI)-induced DNA damage in 14 day chick embryos: Cr-DNA binding in liver and 8-oxo-2'-deoxyguanosine in red blood cells. Carcinogenesis. 15: 2911-7. PMID 8001255 |
0.388 |
|
1994 |
Stearns DM, Courtney KD, Giangrande PH, Phieffer LS, Wetterhahn KE. Chromium(VI) reduction by ascorbate: role of reactive intermediates in DNA damage in vitro. Environmental Health Perspectives. 102: 21-5. PMID 7843100 DOI: 10.1289/Ehp.94102S321 |
0.366 |
|
1992 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes. Archives of Biochemistry and Biophysics. 298: 96-104. PMID 1524447 DOI: 10.1016/0003-9861(92)90099-I |
0.549 |
|
1991 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Alcedo JA, Wetterhahn KE. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. Archives of Biochemistry and Biophysics. 289: 387-92. PMID 1898078 DOI: 10.1016/0003-9861(91)90428-L |
0.539 |
|
1991 |
Borges KM, Boswell JS, Liebross RH, Wetterhahn KE. Activation of chromium(VI) by thiols results in chromium(V) formation, chromium binding to DNA and altered DNA conformation. Carcinogenesis. 12: 551-61. PMID 1849467 |
0.357 |
|
1991 |
Borges KM, Wetterhahn KE. Chromium bound to DNA alters cleavage by restriction endonucleases. Chemical Research in Toxicology. 4: 638-41. PMID 1666962 |
0.329 |
|
1991 |
Aiyar J, Berkovits HJ, Floyd RA, Wetterhahn KE. Reaction of chromium(VI) with glutathione or with hydrogen peroxide: identification of reactive intermediates and their role in chromium(VI)-induced DNA damage. Environmental Health Perspectives. 92: 53-62. PMID 1657590 DOI: 10.1289/ehp.919253 |
0.351 |
|
1989 |
Borges KM, Wetterhahn KE. Chromium cross-links glutathione and cysteine to DNA. Carcinogenesis. 10: 2165-8. PMID 2805236 |
0.358 |
|
1989 |
Hamilton JW, Wetterhahn KE. Differential effects of chromium(VI) on constitutive and inducible gene expression in chick embryo liver in vivo and correlation with chromium(VI)-induced DNA damage Molecular Carcinogenesis. 2: 274-286. PMID 2604865 DOI: 10.1002/Mc.2940020508 |
0.619 |
|
1989 |
Wetterhahn KE, Hamilton JW. Molecular basis of hexavalent chromium carcinogenicity: effect on gene expression. The Science of the Total Environment. 86: 113-29. PMID 2602931 DOI: 10.1016/0048-9697(89)90199-X |
0.628 |
|
1989 |
Wetterhahn KE, Hamilton JW, Aiyar J, Borges KM, Floyd R. Mechanism of chromium(VI) carcinogenesis. Reactive intermediates and effect on gene expression. Biological Trace Element Research. 21: 405-11. PMID 2484620 DOI: 10.1007/Bf02917282 |
0.598 |
|
1989 |
Standeven AM, Wetterhahn KE. Chromium(VI) Toxicity: Uptake, Reduction, and DNA Damage Journal of the American College of Toxicology. 8: 1275-1283. DOI: 10.3109/10915818909009118 |
0.357 |
|
1988 |
Hamilton JW, Bement WJ, Sinclair PR, Sinclair JF, Wetterhahn KE. Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem Biochemical Journal. 255: 267-275. PMID 3196319 DOI: 10.1042/Bj2570936 |
0.53 |
|
1986 |
Hamilton JW, Wetterhahn KE. Chromium (vi)-induced dna damage in chick embryo liver and blood cells in vivo Carcinogenesis. 7: 2085-2088. PMID 3779902 DOI: 10.1093/Carcin/7.12.2085 |
0.575 |
|
1985 |
Cupo DY, Wetterhahn KE. Repair of chromate-induced DNA damage in chick embryo hepatocytes. Carcinogenesis. 5: 1705-8. PMID 6499121 DOI: 10.1093/CARCIN/5.12.1705 |
0.416 |
|
1985 |
Cupo DY, Wetterhahn KE. Modification of chromium(VI)-induced DNA damage by glutathione and cytochromes P-450 in chicken embryo hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 82: 6755-9. PMID 3863126 DOI: 10.1073/PNAS.82.20.6755 |
0.394 |
|
1985 |
Cupo DY, Wetterhahn KE. Binding of chromium to chromatin and DNA from liver and kidney of rats treated with sodium dichromate and chromium(III) chloride in vivo. Cancer Research. 45: 1146-51. PMID 2578874 |
0.371 |
|
1984 |
Ciccarelli RB, Wetterhahn KE. Molecular basis for the activity of nickel. Iarc Scientific Publications. 201-13. PMID 6085326 |
0.364 |
|
1983 |
Tsapakos MJ, Hampton TH, Sinclair PR, Sinclair JF, Bement WJ, Wetterhahn KE. The carcinogen chromate causes DNA damage and inhibits drug-mediated induction of porphyrin accumulation and glucuronidation in chick embryo hepatocytes. Carcinogenesis. 4: 959-66. PMID 6872154 DOI: 10.1093/CARCIN/4.8.959 |
0.413 |
|
1983 |
Tsapakos MJ, Hampton TH, Wetterhahn KE. Chromium(VI)-induced DNA lesions and chromium distribution in rat kidney, liver, and lung. Cancer Research. 43: 5662-7. PMID 6640521 |
0.357 |
|
1983 |
Tsapakos MJ, Wetterhahn KE. The interaction of chromium with nucleic acids. Chemico-Biological Interactions. 46: 265-77. PMID 6627506 DOI: 10.1016/0009-2797(83)90034-0 |
0.352 |
|
1982 |
Ciccarelli RB, Wetterhahn KE. Nickel distribution and DNA lesions induced in rat tissues by the carcinogen nickel carbonate. Cancer Research. 42: 3544-9. PMID 7105030 |
0.354 |
|
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