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Feng Yan, Ph.D. - Publications

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Psychopharmacology, 5-HT2A receptors, hallucinogens
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Fichna J, Lewellyn K, Yan F, Roth BL, Zjawiony JK. Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acids. Bioorganic & Medicinal Chemistry Letters. 21: 160-3. PMID 21115248 DOI: 10.1016/J.Bmcl.2010.11.046  0.606
2011 Fichna J, Lewellyn K, Yan F, Roth BL, Zjawiony JK. Synthesis and in vitro characterization of new salvinorin a analogs incorporating natural amino acids Pharmacological Reports. 63: 232-233. DOI: 10.1016/S1734-1140(11)70453-4  0.438
2009 Yan F, Bikbulatov RV, Mocanu V, Dicheva N, Parker CE, Wetsel WC, Mosier PD, Westkaemper RB, Allen JA, Zjawiony JK, Roth BL. Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor. Biochemistry. 48: 6898-908. PMID 19555087 DOI: 10.1021/Bi900605N  0.702
2008 Bikbulatov RV, Stewart J, Jin W, Yan F, Roth BL, Ferreira D, Zjawiony JK. Short synthesis of a novel class of salvinorin A analogs with hemiacetalic structure. Tetrahedron Letters. 49: 937-940. PMID 19197341 DOI: 10.1016/J.Tetlet.2007.12.041  0.646
2008 Pei Y, Rogan SC, Yan F, Roth BL. Engineered GPCRs as tools to modulate signal transduction. Physiology (Bethesda, Md.). 23: 313-21. PMID 19074739 DOI: 10.1152/Physiol.00025.2008  0.667
2008 Yan F, Mosier PD, Westkaemper RB, Roth BL. Galpha-subunits differentially alter the conformation and agonist affinity of kappa-opioid receptors. Biochemistry. 47: 1567-78. PMID 18205395 DOI: 10.1021/Bi701476B  0.575
2007 Bikbulatov RV, Yan F, Roth BL, Zjawiony JK. Convenient synthesis and in vitro pharmacological activity of 2-thioanalogs of salvinorins A and B. Bioorganic & Medicinal Chemistry Letters. 17: 2229-32. PMID 17303418 DOI: 10.1016/J.Bmcl.2007.01.100  0.665
2007 Yan F, Roth B. G-protein alpha subunits differentially alter the conformation of kappa opioid receptor The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A429-C  0.568
2006 Stewart DJ, Fahmy H, Roth BL, Yan F, Zjawiony JK. Bioisosteric modification of salvinorin A, a potent and selective kappa-opioid receptor agonist. Arzneimittel-Forschung. 56: 269-75. PMID 16724512 DOI: 10.1055/S-0031-1296720  0.623
2005 Beeler AB, Acquilano DE, Su Q, Yan F, Roth BL, Panek JS, Porco JA. Synthesis of a library of complex macrodiolides employing cyclodimerization of hydroxy esters. Journal of Combinatorial Chemistry. 7: 673-81. PMID 16153061 DOI: 10.1021/Cc050064B  0.545
2005 Yan F, Mosier PD, Westkaemper RB, Stewart J, Zjawiony JK, Vortherms TA, Sheffler DJ, Roth BL. Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to kappa-opioid receptors. Biochemistry. 44: 8643-51. PMID 15952771 DOI: 10.1021/Bi050490D  0.716
2005 Munro TA, Rizzacasa MA, Roth BL, Toth BA, Yan F. Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist. Journal of Medicinal Chemistry. 48: 345-8. PMID 15658846 DOI: 10.1021/Jm049438Q  0.662
2004 Yan F, Roth BL. Salvinorin A: a novel and highly selective kappa-opioid receptor agonist. Life Sciences. 75: 2615-9. PMID 15369697 DOI: 10.1016/J.Lfs.2004.07.008  0.619
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