Alexander Schier - Publications

Affiliations: 
1996-2005 Skirball Institute New York University School of Medicine, New York, NY, United States 
 2005- Harvard University, Cambridge, MA, United States 
Area:
Development, Sleep

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Haesemeyer M, Robson DN, Li JM, Schier AF, Engert F. A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. Neuron. 98: 817-831.e6. PMID 29731253 DOI: 10.1016/j.neuron.2018.04.013  0.6
2018 Rabani M, Pieper L, Chew GL, Schier AF. A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell. 70: 565. PMID 29727622 DOI: 10.1016/j.molcel.2018.04.013  0.56
2018 Raj B, Wagner DE, McKenna A, Pandey S, Klein AM, Shendure J, Gagnon JA, Schier AF. Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. Nature Biotechnology. PMID 29608178 DOI: 10.1038/nbt.4103  1
2017 Rabani M, Pieper L, Chew GL, Schier AF. A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell. PMID 29225039 DOI: 10.1016/j.molcel.2017.11.014  0.56
2017 Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF. Nodal patterning without Lefty inhibitory feedback is functional but fragile. Elife. 6. PMID 29215332 DOI: 10.7554/eLife.28785  1
2017 Gagnon JA, Obbad K, Schier AF. Zebrafish nanog is primarily required in extraembryonic tissue. Development (Cambridge, England). PMID 29180571 DOI: 10.1242/dev.147793  1
2017 Montague TG, Schier AF. Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm. Elife. 6. PMID 29140251 DOI: 10.7554/eLife.28183  1
2017 Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 6. PMID 29117894 DOI: 10.7554/eLife.22626  1
2017 Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-García IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, ... Schier AF, et al. Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. PMID 29088697 DOI: 10.1038/nature24470  0.44
2017 Freyer L, Hsu CW, Nowotschin S, Pauli A, Ishida J, Kuba K, Fukamizu A, Schier AF, Hoodless PA, Dickinson ME, Hadjantonakis AK. Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell Reports. 20: 2116-2130. PMID 28854362 DOI: 10.1016/j.celrep.2017.08.014  0.56
2017 Hildebrand DGC, Cicconet M, Torres RM, Choi W, Quan TM, Moon J, Wetzel AW, Scott Champion A, Graham BJ, Randlett O, Plummer GS, Portugues R, Bianco IH, Saalfeld S, Baden AD, ... ... Schier AF, et al. Whole-brain serial-section electron microscopy in larval zebrafish. Nature. PMID 28489821 DOI: 10.1038/nature22356  0.72
2016 Thyme SB, Akhmetova L, Montague TG, Valen E, Schier AF. Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature Communications. 7: 11750. PMID 27282953 DOI: 10.1038/ncomms11750  1
2016 McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J. Whole organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.). PMID 27229144 DOI: 10.1126/science.aaf7907  1
2016 Chew GL, Pauli A, Schier AF. Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish. Nature Communications. 7: 11663. PMID 27216465 DOI: 10.1038/ncomms11663  0.56
2016 Thyme SB, Schier AF. Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Reports. 15: 1611-1613. PMID 27192698 DOI: 10.1016/j.celrep.2016.04.089  0.44
2016 Thyme SB, Schier AF. Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Reports. PMID 27149851 DOI: 10.1016/j.celrep.2016.03.072  0.44
2016 Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens CB, Shin J, Sawada A, Hindes AE, Dubrulle J, Schier AF, Longmore GD, Marlow FL, Solnica-Krezel L. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). PMID 27127268 DOI: 10.1242/dev.138859  0.68
2016 Dunn TW, Mu Y, Narayan S, Randlett O, Naumann EA, Yang CT, Schier AF, Freeman J, Engert F, Ahrens MB. Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. Elife. 5. PMID 27003593 DOI: 10.7554/eLife.12741  1
2016 Chiu CN, Rihel J, Lee DA, Singh C, Mosser EA, Chen S, Sapin V, Pham U, Engle J, Niles BJ, Montz CJ, Chakravarthy S, Zimmerman S, Salehi-Ashtiani K, Vidal M, ... Schier AF, et al. A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 89: 842-56. PMID 26889812 DOI: 10.1016/j.neuron.2016.01.007  1
2015 Randlett O, Wee CL, Naumann EA, Nnaemeka O, Schoppik D, Fitzgerald JE, Portugues R, Lacoste AM, Riegler C, Engert F, Schier AF. Whole-brain activity mapping onto a zebrafish brain atlas. Nature Methods. 12: 1039-1046. PMID 26778924 DOI: 10.1038/nmeth.3581  1
2015 Haesemeyer M, Robson DN, Li JM, Schier AF, Engert F. The structure and timescales of heat perception in larval zebrafish. Cell Systems. 1: 338-348. PMID 26640823 DOI: 10.1016/j.cels.2015.10.010  1
2015 Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. Plos One. 10: e0139504. PMID 26436892 DOI: 10.1371/journal.pone.0139504  1
2015 Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens CB, Shin J, Sawada A, Hindes AE, Dubrulle J, Schier AF, Longmore GD, Marlow FL, Solnica-Krezel L. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (Cambridge, England). PMID 26160902 DOI: 10.1242/dev.119800  1
2015 Lacoste AM, Schoppik D, Robson DN, Haesemeyer M, Portugues R, Li JM, Randlett O, Wee CL, Engert F, Schier AF. A convergent and essential interneuron pathway for mauthner-cell-mediated escapes. Current Biology : Cb. 25: 1526-34. PMID 25959971 DOI: 10.1016/j.cub.2015.04.025  1
2015 Merkle FT, Neuhausser WM, Santos D, Valen E, Gagnon JA, Maas K, Sandoe J, Schier AF, Eggan K. Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus. Cell Reports. 11: 875-83. PMID 25937281 DOI: 10.1016/j.celrep.2015.04.007  1
2015 Dubrulle J, Jordan BM, Akhmetova L, Farrell JA, Kim SH, Solnica-Krezel L, Schier AF. Response to Nodal morphogen gradient is determined by the kinetics of target gene induction. Elife. 4. PMID 25869585 DOI: 10.7554/eLife.05042  1
2015 Satija R, Farrell JA, Gennert D, Schier AF, Regev A. Spatial reconstruction of single-cell gene expression data. Nature Biotechnology. 33: 495-502. PMID 25867923 DOI: 10.1038/nbt.3192  1
2015 Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142: 1113-24. PMID 25725064 DOI: 10.1242/dev.117424  1
2015 Mundell NA, Beier KT, Pan YA, Lapan SW, Göz Aytürk D, Berezovskii VK, Wark AR, Drokhlyansky E, Bielecki J, Born RT, Schier AF, Cepko CL. Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. The Journal of Comparative Neurology. 523: 1639-63. PMID 25688551 DOI: 10.1002/cne.23761  1
2015 Merkle FT, Maroof A, Wataya T, Sasai Y, Studer L, Eggan K, Schier AF. Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England). 142: 633-43. PMID 25670790 DOI: 10.1242/dev.117978  1
2015 Rogers KW, Blässle A, Schier AF, Müller P. Measuring protein stability in living zebrafish embryos using fluorescence decay after photoconversion (FDAP). Journal of Visualized Experiments : Jove. 52266. PMID 25650549 DOI: 10.3791/52266  1
2015 Haesemeyer M, Schier AF. The study of psychiatric disease genes and drugs in zebrafish. Current Opinion in Neurobiology. 30: 122-30. PMID 25523356 DOI: 10.1016/j.conb.2014.12.002  1
2015 Pauli A, Valen E, Schier AF. Identifying (non-)coding RNAs and small peptides: challenges and opportunities. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 103-12. PMID 25345765 DOI: 10.1002/bies.201400103  1
2014 Rabani M, Raychowdhury R, Jovanovic M, Rooney M, Stumpo DJ, Pauli A, Hacohen N, Schier AF, Blackshear PJ, Friedman N, Amit I, Regev A. High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell. 159: 1698-710. PMID 25497548 DOI: 10.1016/j.cell.2014.11.015  1
2014 Schier AF. Obituary: Walter J. Gehring (1939-2014). Development (Cambridge, England). 141: 3289-91. PMID 25085977 DOI: 10.1242/dev.115402  1
2014 Richter C, Woods IG, Schier AF. Neuropeptidergic control of sleep and wakefulness. Annual Review of Neuroscience. 37: 503-31. PMID 25032501 DOI: 10.1146/annurev-neuro-062111-150447  1
2014 Gagnon JA, Valen E, Thyme SB, Huang P, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. Plos One. 9: e98186. PMID 24873830 DOI: 10.1371/journal.pone.0098186  1
2014 Woods IG, Schoppik D, Shi VJ, Zimmerman S, Coleman HA, Greenwood J, Soucy ER, Schier AF. Neuropeptidergic signaling partitions arousal behaviors in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3142-60. PMID 24573274 DOI: 10.1523/JNEUROSCI.3529-13.2014  1
2014 Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF. Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (New York, N.Y.). 343: 1248636. PMID 24407481 DOI: 10.1126/science.1248636  1
2014 Zhang Y, Vastenhouw NL, Feng J, Fu K, Wang C, Ge Y, Pauli A, van Hummelen P, Schier AF, Liu XS. Canonical nucleosome organization at promoters forms during genome activation. Genome Research. 24: 260-6. PMID 24285721 DOI: 10.1101/gr.157750.113  1
2013 Schier AF. Should I stay or should I go: neuromodulators of behavioral states. Cell. 154: 955-6. PMID 23993087 DOI: 10.1016/j.cell.2013.08.017  1
2013 Pan YA, Freundlich T, Weissman TA, Schoppik D, Wang XC, Zimmerman S, Ciruna B, Sanes JR, Lichtman JW, Schier AF. Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (Cambridge, England). 140: 2835-46. PMID 23757414 DOI: 10.1242/dev.094631  1
2013 Rihel J, Schier AF. Sites of action of sleep and wake drugs: insights from model organisms. Current Opinion in Neurobiology. 23: 831-40. PMID 23706898 DOI: 10.1016/j.conb.2013.04.010  1
2013 Chew GL, Pauli A, Rinn JL, Regev A, Schier AF, Valen E. Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development (Cambridge, England). 140: 2828-34. PMID 23698349 DOI: 10.1242/dev.098343  1
2013 Xiong F, Tentner AR, Huang P, Gelas A, Mosaliganti KR, Souhait L, Rannou N, Swinburne IA, Obholzer ND, Cowgill PD, Schier AF, Megason SG. Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell. 153: 550-61. PMID 23622240 DOI: 10.1016/j.cell.2013.03.023  1
2013 Schier AF. Genomics: Zebrafish earns its stripes. Nature. 496: 443-4. PMID 23594741 DOI: 10.1038/nature12094  1
2013 Müller P, Rogers KW, Yu SR, Brand M, Schier AF. Morphogen transport. Development (Cambridge, England). 140: 1621-38. PMID 23533171 DOI: 10.1242/dev.083519  1
2013 Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16: 507-16. PMID 23455609 DOI: 10.1038/nn.3346  1
2013 Varshney GK, Lu J, Gildea DE, Huang H, Pei W, Yang Z, Huang SC, Schoenfeld D, Pho NH, Casero D, Hirase T, Mosbrook-Davis D, Zhang S, Jao LE, Zhang B, ... ... Schier AF, et al. A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Research. 23: 727-35. PMID 23382537 DOI: 10.1101/gr.151464.112  1
2012 Bianco IH, Ma LH, Schoppik D, Robson DN, Orger MB, Beck JC, Li JM, Schier AF, Engert F, Baker R. The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. Current Biology : Cb. 22: 1285-95. PMID 22704987 DOI: 10.1016/j.cub.2012.05.026  1
2012 Huang P, Xiong F, Megason SG, Schier AF. Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord. Plos Genetics. 8: e1002762. PMID 22685423 DOI: 10.1371/journal.pgen.1002762  1
2012 Ahrens MB, Li JM, Orger MB, Robson DN, Schier AF, Engert F, Portugues R. Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature. 485: 471-7. PMID 22622571 DOI: 10.1038/nature11057  1
2012 Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, ... ... Schier AF, et al. CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature Genetics. 44: 714-9. PMID 22581229 DOI: 10.1038/ng.2277  1
2012 Vastenhouw NL, Schier AF. Bivalent histone modifications in early embryogenesis. Current Opinion in Cell Biology. 24: 374-86. PMID 22513113 DOI: 10.1016/j.ceb.2012.03.009  1
2012 Müller P, Rogers KW, Jordan BM, Lee JS, Robson D, Ramanathan S, Schier AF. Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science (New York, N.Y.). 336: 721-4. PMID 22499809 DOI: 10.1126/science.1221920  1
2012 Low SE, Woods IG, Lachance M, Ryan J, Schier AF, Saint-Amant L. Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of Neurophysiology. 108: 148-59. PMID 22490555 DOI: 10.1152/jn.00839.2011  1
2012 Stooke-Vaughan GA, Huang P, Hammond KL, Schier AF, Whitfield TT. The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England). 139: 1777-87. PMID 22461562 DOI: 10.1242/dev.079947  1
2012 Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell. 22: 625-38. PMID 22421047 DOI: 10.1016/j.devcel.2012.01.003  1
2012 Pan YA, Caron SJ, Schier AF. BAPTI and BAPTISM birthdating of neurons in zebrafish. Cold Spring Harbor Protocols. 2012: 87-92. PMID 22194263 DOI: 10.1101/pdb.prot067520  1
2012 Pan YA, Choy M, Prober DA, Schier AF. Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development (Cambridge, England). 139: 591-600. PMID 22190641 DOI: 10.1242/dev.076588  1
2012 Pauli A, Valen E, Lin MF, Garber M, Vastenhouw NL, Levin JZ, Fan L, Sandelin A, Rinn JL, Regev A, Schier AF. Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. Genome Research. 22: 577-91. PMID 22110045 DOI: 10.1101/gr.133009.111  1
2012 Rihel J, Schier AF. Behavioral screening for neuroactive drugs in zebrafish. Developmental Neurobiology. 72: 373-85. PMID 21567979 DOI: 10.1002/dneu.20910  1
2011 Laukens B, Jennewein C, Schenk B, Vanlangenakker N, Schier A, Cristofanon S, Zobel K, Deshayes K, Vucic D, Jeremias I, Bertrand MJ, Vandenabeele P, Fulda S. Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis. Neoplasia (New York, N.Y.). 13: 971-9. PMID 22028622 DOI: 10.1593/neo.11610  1
2011 Rogers KW, Schier AF. Morphogen gradients: from generation to interpretation. Annual Review of Cell and Developmental Biology. 27: 377-407. PMID 21801015 DOI: 10.1146/annurev-cellbio-092910-154148  1
2011 Müller P, Schier AF. Extracellular movement of signaling molecules. Developmental Cell. 21: 145-58. PMID 21763615 DOI: 10.1016/j.devcel.2011.06.001  1
2011 Schier A. Guided by the light: neutrophil migration through zebrafish Developmental Cell. 20: e2. PMID 21411394  1
2011 Pauli A, Rinn JL, Schier AF. Non-coding RNAs as regulators of embryogenesis. Nature Reviews. Genetics. 12: 136-49. PMID 21245830 DOI: 10.1038/nrg2904  1
2011 Pan YA, Livet J, Sanes JR, Lichtman JW, Schier AF. Multicolor Brainbow imaging in zebrafish. Cold Spring Harbor Protocols. 2011: pdb.prot5546. PMID 21205846 DOI: 10.1101/pdb.prot5546  1
2010 Rihel J, Prober DA, Schier AF. Monitoring sleep and arousal in zebrafish. Methods in Cell Biology. 100: 281-94. PMID 21111222 DOI: 10.1016/B978-0-12-384892-5.00011-6  1
2010 Vastenhouw NL, Zhang Y, Woods IG, Imam F, Regev A, Liu XS, Rinn J, Schier AF. Chromatin signature of embryonic pluripotency is established during genome activation. Nature. 464: 922-6. PMID 20336069 DOI: 10.1038/nature08866  1
2010 Naumann EA, Kampff AR, Prober DA, Schier AF, Engert F. Monitoring neural activity with bioluminescence during natural behavior. Nature Neuroscience. 13: 513-20. PMID 20305645 DOI: 10.1038/nn.2518  1
2010 Harvey SA, Tümpel S, Dubrulle J, Schier AF, Smith JC. no tail integrates two modes of mesoderm induction. Development (Cambridge, England). 137: 1127-35. PMID 20215349 DOI: 10.1242/dev.046318  1
2010 Rihel J, Prober DA, Arvanites A, Lam K, Zimmerman S, Jang S, Haggarty SJ, Kokel D, Rubin LL, Peterson RT, Schier AF. Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science (New York, N.Y.). 327: 348-51. PMID 20075256 DOI: 10.1126/science.1183090  1
2009 Schier AF. Nodal morphogens. Cold Spring Harbor Perspectives in Biology. 1: a003459. PMID 20066122 DOI: 10.1101/cshperspect.a003459  1
2009 Schier AF, Needleman D. Developmental biology: Rise of the source-sink model. Nature. 461: 480-1. PMID 19779439 DOI: 10.1038/461480a  1
2009 Huang P, Schier AF. Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England). 136: 3089-98. PMID 19700616 DOI: 10.1242/dev.041343  1
2008 de Campos-Baptista MI, Holtzman NG, Yelon D, Schier AF. Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3624-33. PMID 18985714 DOI: 10.1002/dvdy.21777  1
2008 Prober DA, Zimmerman S, Myers BR, McDermott BM, Kim SH, Caron S, Rihel J, Solnica-Krezel L, Julius D, Hudspeth AJ, Schier AF. Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10102-10. PMID 18829968 DOI: 10.1523/JNEUROSCI.2740-08.2008  1
2008 Caron SJ, Prober D, Choy M, Schier AF. In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development (Cambridge, England). 135: 3259-69. PMID 18755773 DOI: 10.1242/dev.023200  1
2008 Douglass AD, Kraves S, Deisseroth K, Schier AF, Engert F. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current Biology : Cb. 18: 1133-7. PMID 18682213 DOI: 10.1016/j.cub.2008.06.077  1
2008 Woods IG, Schier AF. Targeted mutagenesis in zebrafish. Nature Biotechnology. 26: 650-1. PMID 18536686 DOI: 10.1038/nbt0608-650  1
2008 Knaut H, Schier AF. Clearing the path for germ cells. Cell. 132: 337-9. PMID 18267065 DOI: 10.1016/j.cell.2008.01.023  1
2008 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz HR, Schier AF, Dulac C. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 57: 41-55. PMID 18184563 DOI: 10.1016/j.neuron.2007.11.018  0.88
2007 Bennett JT, Stickney HL, Choi WY, Ciruna B, Talbot WS, Schier AF. Maternal nodal and zebrafish embryogenesis. Nature. 450: E1-2; discussion E2-. PMID 17994032 DOI: 10.1038/nature06314  1
2007 Karkera JD, Lee JS, Roessler E, Banerjee-Basu S, Ouspenskaia MV, Mez J, Goldmuntz E, Bowers P, Towbin J, Belmont JW, Baxevanis AD, Schier AF, Muenke M. Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. American Journal of Human Genetics. 81: 987-94. PMID 17924340 DOI: 10.1086/522890  1
2007 Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science (New York, N.Y.). 318: 271-4. PMID 17761850 DOI: 10.1126/science.1147535  1
2007 Schier AF. The maternal-zygotic transition: death and birth of RNAs. Science (New York, N.Y.). 316: 406-7. PMID 17446392 DOI: 10.1126/science.1140693  1
2007 Bennett JT, Joubin K, Cheng S, Aanstad P, Herwig R, Clark M, Lehrach H, Schier AF. Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental Biology. 304: 525-40. PMID 17306247 DOI: 10.1016/j.ydbio.2007.01.012  1
2006 Schier AF, Giraldez AJ. MicroRNA function and mechanism: insights from zebra fish. Cold Spring Harbor Symposia On Quantitative Biology. 71: 195-203. PMID 17381297 DOI: 10.1101/sqb.2006.71.055  1
2006 Prober DA, Rihel J, Onah AA, Sung RJ, Schier AF. Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13400-10. PMID 17182791 DOI: 10.1523/JNEUROSCI.4332-06.2006  1
2006 Mishima Y, Giraldez AJ, Takeda Y, Fujiwara T, Sakamoto H, Schier AF, Inoue K. Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Current Biology : Cb. 16: 2135-42. PMID 17084698 DOI: 10.1016/j.cub.2006.08.086  1
2006 Obara T, Mangos S, Liu Y, Zhao J, Wiessner S, Kramer-Zucker AG, Olale F, Schier AF, Drummond IA. Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology : Jasn. 17: 2706-18. PMID 16943304 DOI: 10.1681/ASN.2006040412  1
2006 Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, Inoue K, Enright AJ, Schier AF. Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science (New York, N.Y.). 312: 75-9. PMID 16484454 DOI: 10.1126/science.1122689  1
2006 Ciruna B, Jenny A, Lee D, Mlodzik M, Schier AF. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature. 439: 220-4. PMID 16407953 DOI: 10.1038/nature04375  1
2005 Schier AF. Axis formation: squint comes into focus. Current Biology : Cb. 15: R1002-5. PMID 16360671 DOI: 10.1016/j.cub.2005.11.051  1
2005 Schier AF, Talbot WS. Molecular genetics of axis formation in zebrafish. Annual Review of Genetics. 39: 561-613. PMID 16285872 DOI: 10.1146/annurev.genet.37.110801.143752  1
2005 Knaut H, Blader P, Strähle U, Schier AF. Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron. 47: 653-66. PMID 16129396 DOI: 10.1016/j.neuron.2005.07.014  1
2005 Sagasti A, Guido MR, Raible DW, Schier AF. Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current Biology : Cb. 15: 804-14. PMID 15886097 DOI: 10.1016/j.cub.2005.03.048  1
2005 Kramer-Zucker AG, Olale F, Haycraft CJ, Yoder BK, Schier AF, Drummond IA. Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (Cambridge, England). 132: 1907-21. PMID 15790966 DOI: 10.1242/dev.01772  1
2005 Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson JM, Baskerville S, Hammond SM, Bartel DP, Schier AF. MicroRNAs regulate brain morphogenesis in zebrafish. Science (New York, N.Y.). 308: 833-8. PMID 15774722 DOI: 10.1126/science.1109020  1
2005 Dutta S, Dietrich JE, Aspöck G, Burdine RD, Schier A, Westerfield M, Varga ZM. pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development (Cambridge, England). 132: 1579-90. PMID 15728669 DOI: 10.1242/dev.01723  1
2005 Le Good JA, Joubin K, Giraldez AJ, Ben-Haim N, Beck S, Chen Y, Schier AF, Constam DB. Nodal stability determines signaling range. Current Biology : Cb. 15: 31-6. PMID 15649361 DOI: 10.1016/j.cub.2004.12.062  1
2005 Tyurina OV, Guner B, Popova E, Feng J, Schier AF, Kohtz JD, Karlstrom RO. Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental Biology. 277: 537-56. PMID 15617692 DOI: 10.1016/j.ydbio.2004.10.003  1
2004 Schier A. Alexander Schier Current Biology : Cb. 14: R494. PMID 15242623  1
2004 Nakano Y, Kim HR, Kawakami A, Roy S, Schier AF, Ingham PW. Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Developmental Biology. 269: 381-92. PMID 15110707 DOI: 10.1016/j.ydbio.2004.01.022  1
2004 Cheng SK, Olale F, Brivanlou AH, Schier AF. Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. Plos Biology. 2: E30. PMID 14966532 DOI: 10.1371/journal.pbio.0020030  1
2004 Schier AF. Developmental biology: tail of decay. Nature. 427: 403-4. PMID 14749811 DOI: 10.1038/427403a  1
2003 Schier AF. Nodal signaling in vertebrate development. Annual Review of Cell and Developmental Biology. 19: 589-621. PMID 14570583 DOI: 10.1146/annurev.cellbio.19.041603.094522  1
2003 Kunwar PS, Zimmerman S, Bennett JT, Chen Y, Whitman M, Schier AF. Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development (Cambridge, England). 130: 5589-99. PMID 14522874 DOI: 10.1242/dev.00803  1
2003 Dougan ST, Warga RM, Kane DA, Schier AF, Talbot WS. The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development (Cambridge, England). 130: 1837-51. PMID 12642489 DOI: 10.1242/dev.00400  1
2003 Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF. Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development (Cambridge, England). 130: 1549-64. PMID 12620981 DOI: 10.1242/dev.00364  1
2003 Schier AF. Chemokine signaling: rules of attraction. Current Biology : Cb. 13: R192-4. PMID 12620211 DOI: 10.1016/S0960-9822(03)00122-2  1
2003 Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF. EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes & Development. 17: 31-6. PMID 12514096 DOI: 10.1101/gad.1041203  1
2002 Chen Y, Schier AF. Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. Current Biology : Cb. 12: 2124-8. PMID 12498687 DOI: 10.1016/S0960-9822(02)01362-3  1
2002 Ciruna B, Weidinger G, Knaut H, Thisse B, Thisse C, Raz E, Schier AF. Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America. 99: 14919-24. PMID 12397179 DOI: 10.1073/pnas.222459999  1
2002 Kimelman D, Schier AF. Mesoderm induction and patterning. Results and Problems in Cell Differentiation. 40: 15-27. PMID 12353475  1
2002 Moon HS, Jacobson EM, Khersonsky SM, Luzung MR, Walsh DP, Xiong W, Lee JW, Parikh PB, Lam JC, Kang TW, Rosania GR, Schier AF, Chang YT. A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society. 124: 11608-9. PMID 12296721 DOI: 10.1021/ja026720i  1
2002 de la Cruz JM, Bamford RN, Burdine RD, Roessler E, Barkovich AJ, Donnai D, Schier AF, Muenke M. A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human Genetics. 110: 422-8. PMID 12073012 DOI: 10.1007/s00439-002-0709-3  1
2002 Yamashita S, Miyagi C, Carmany-Rampey A, Shimizu T, Fujii R, Schier AF, Hirano T. Stat3 Controls Cell Movements during Zebrafish Gastrulation. Developmental Cell. 2: 363-75. PMID 11879641 DOI: 10.1016/S1534-5807(02)00126-0  1
2001 Carmany-Rampey A, Schier AF. Single-cell internalization during zebrafish gastrulation. Current Biology : Cb. 11: 1261-5. PMID 11525740 DOI: 10.1016/S0960-9822(01)00353-0  1
2001 Imai Y, Gates MA, Melby AE, Kimelman D, Schier AF, Talbot WS. The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish. Development (Cambridge, England). 128: 2407-20. PMID 11493559  1
2001 Schier AF. Axis formation and patterning in zebrafish. Current Opinion in Genetics & Development. 11: 393-404. PMID 11448625 DOI: 10.1016/S0959-437X(00)00209-4  1
2001 Schier AF, Talbot WS. Nodal signaling and the zebrafish organizer. The International Journal of Developmental Biology. 45: 289-97. PMID 11291859  1
2000 Concha ML, Burdine RD, Russell C, Schier AF, Wilson SW. A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. Neuron. 28: 399-409. PMID 11144351  1
2000 Bamford RN, Roessler E, Burdine RD, SaplakoÄŸlu U, dela Cruz J, Splitt M, Goodship JA, Towbin J, Bowers P, Ferrero GB, Marino B, Schier AF, Shen MM, Muenke M, Casey B. Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects. Nature Genetics. 26: 365-9. PMID 11062482 DOI: 10.1038/81695  1
2000 Sirotkin HI, Gates MA, Kelly PD, Schier AF, Talbot WS. Fast1 is required for the development of dorsal axial structures in zebrafish. Current Biology : Cb. 10: 1051-4. PMID 10996072 DOI: 10.1016/S0960-9822(00)00679-5  1
2000 Shen MM, Schier AF. The EGF-CFC gene family in vertebrate development. Trends in Genetics : Tig. 16: 303-9. PMID 10858660 DOI: 10.1016/S0168-9525(00)02006-0  1
2000 Sirotkin HI, Dougan ST, Schier AF, Talbot WS. bozozok and squint act in parallel to specify dorsal mesoderm and anterior neuroectoderm in zebrafish. Development (Cambridge, England). 127: 2583-92. PMID 10821757  1
2000 Feldman B, Dougan ST, Schier AF, Talbot WS. Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish. Current Biology : Cb. 10: 531-4. PMID 10801442  0.72
2000 Imai Y, Feldman B, Schier AF, Talbot WS. Analysis of chromosomal rearrangements induced by postmeiotic mutagenesis with ethylnitrosourea in zebrafish. Genetics. 155: 261-72. PMID 10790400  0.72
2000 Kelly PD, Chu F, Woods IG, Ngo-Hazelett P, Cardozo T, Huang H, Kimm F, Liao L, Yan YL, Zhou Y, Johnson SL, Abagyan R, Schier AF, Postlethwait JH, Talbot WS. Genetic linkage mapping of zebrafish genes and ESTs. Genome Research. 10: 558-67. PMID 10779498 DOI: 10.1101/gr.10.4.558  1
2000 Burdine RD, Schier AF. Conserved and divergent mechanisms in left-right axis formation. Genes & Development. 14: 763-76. PMID 10766733  1
2000 Schier AF, Shen MM. Nodal signalling in vertebrate development. Nature. 403: 385-9. PMID 10667782 DOI: 10.1038/35000126  1
2000 Gritsman K, Talbot WS, Schier AF. Nodal signaling patterns the organizer. Development (Cambridge, England). 127: 921-32. PMID 10662632  1
2000 Dick A, Hild M, Bauer H, Imai Y, Maifeld H, Schier AF, Talbot WS, Bouwmeester T, Hammerschmidt M. Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo. Development (Cambridge, England). 127: 343-54. PMID 10603351  0.72
1999 Yan YT, Gritsman K, Ding J, Burdine RD, Corrales JD, Price SM, Talbot WS, Schier AF, Shen MM. Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes & Development. 13: 2527-37. PMID 10521397 DOI: 10.1101/gad.13.19.2527  1
1999 Meno C, Gritsman K, Ohishi S, Ohfuji Y, Heckscher E, Mochida K, Shimono A, Kondoh H, Talbot WS, Robertson EJ, Schier AF, Hamada H. Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Molecular Cell. 4: 287-98. PMID 10518210 DOI: 10.1016/S1097-2765(00)80331-7  1
1999 Geisler R, Rauch GJ, Baier H, van Bebber F, Bross L, Dekens MP, Finger K, Fricke C, Gates MA, Geiger H, Geiger-Rudolph S, Gilmour D, Glaser S, Gnügge L, Habeck H, ... ... Schier AF, et al. A radiation hybrid map of the zebrafish genome. Nature Genetics. 23: 86-9. PMID 10471505 DOI: 10.1038/12692  1
1999 Gates MA, Kim L, Egan ES, Cardozo T, Sirotkin HI, Dougan ST, Lashkari D, Abagyan R, Schier AF, Talbot WS. A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Genome Research. 9: 334-47. PMID 10207156  1
1999 Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell. 97: 121-32. PMID 10199408  1
1999 Fekany K, Yamanaka Y, Leung T, Sirotkin HI, Topczewski J, Gates MA, Hibi M, Renucci A, Stemple D, Radbill A, Schier AF, Driever W, Hirano T, Talbot WS, Solnica-Krezel L. The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development (Cambridge, England). 126: 1427-38. PMID 10068636  1
1999 Karlstrom RO, Talbot WS, Schier AF. Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes & Development. 13: 388-93. PMID 10049354  1
1999 Talbot WS, Schier AF. Positional cloning of mutated zebrafish genes. Methods in Cell Biology. 60: 259-86. PMID 9891342  0.72
1998 Drummond IA, Majumdar A, Hentschel H, Elger M, Solnica-Krezel L, Schier AF, Neuhauss SC, Stemple DL, Zwartkruis F, Rangini Z, Driever W, Fishman MC. Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (Cambridge, England). 125: 4655-67. PMID 9806915  1
1998 Feldman B, Gates MA, Egan ES, Dougan ST, Rennebeck G, Sirotkin HI, Schier AF, Talbot WS. Zebrafish organizer development and germ-layer formation require nodal-related signals. Nature. 395: 181-5. PMID 9744277 DOI: 10.1038/26013  1
1998 Schier AF, Talbot WS. The zebrafish organizer. Current Opinion in Genetics & Development. 8: 464-71. PMID 9729724  0.72
1998 Zhang J, Talbot WS, Schier AF. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell. 92: 241-51. PMID 9458048  0.72
1997 Schier AF, Neuhauss SC, Helde KA, Talbot WS, Driever W. The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (Cambridge, England). 124: 327-42. PMID 9053309  1
1996 Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Abdelilah S, Stainier DY, Driever W. Mutations affecting craniofacial development in zebrafish. Development (Cambridge, England). 123: 357-67. PMID 9007255  1
1996 Pack M, Solnica-Krezel L, Malicki J, Neuhauss SC, Schier AF, Stemple DL, Driever W, Fishman MC. Mutations affecting development of zebrafish digestive organs. Development (Cambridge, England). 123: 321-8. PMID 9007252  1
1996 Weinstein BM, Schier AF, Abdelilah S, Malicki J, Solnica-Krezel L, Stemple DL, Stainier DY, Zwartkruis F, Driever W, Fishman MC. Hematopoietic mutations in the zebrafish. Development (Cambridge, England). 123: 303-9. PMID 9007250  1
1996 Stainier DY, Fouquet B, Chen JN, Warren KS, Weinstein BM, Meiler SE, Mohideen MA, Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W, Fishman MC. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123: 285-92. PMID 9007248  1
1996 Malicki J, Schier AF, Solnica-Krezel L, Stemple DL, Neuhauss SC, Stainier DY, Abdelilah S, Rangini Z, Zwartkruis F, Driever W. Mutations affecting development of the zebrafish ear. Development (Cambridge, England). 123: 275-83. PMID 9007247  1
1996 Malicki J, Neuhauss SC, Schier AF, Solnica-Krezel L, Stemple DL, Stainier DY, Abdelilah S, Zwartkruis F, Rangini Z, Driever W. Mutations affecting development of the zebrafish retina. Development (Cambridge, England). 123: 263-73. PMID 9007246  1
1996 Abdelilah S, Mountcastle-Shah E, Harvey M, Solnica-Krezel L, Schier AF, Stemple DL, Malicki J, Neuhauss SC, Zwartkruis F, Stainier DY, Rangini Z, Driever W. Mutations affecting neural survival in the zebrafish Danio rerio. Development (Cambridge, England). 123: 217-27. PMID 9007242  1
1996 Schier AF, Neuhauss SC, Harvey M, Malicki J, Solnica-Krezel L, Stainier DY, Zwartkruis F, Abdelilah S, Stemple DL, Rangini Z, Yang H, Driever W. Mutations affecting the development of the embryonic zebrafish brain. Development (Cambridge, England). 123: 165-78. PMID 9007238  1
1996 Stemple DL, Solnica-Krezel L, Zwartkruis F, Neuhauss SC, Schier AF, Malicki J, Stainier DY, Abdelilah S, Rangini Z, Mountcastle-Shah E, Driever W. Mutations affecting development of the notochord in zebrafish. Development (Cambridge, England). 123: 117-28. PMID 9007234  1
1996 Solnica-Krezel L, Stemple DL, Mountcastle-Shah E, Rangini Z, Neuhauss SC, Malicki J, Schier AF, Stainier DY, Zwartkruis F, Abdelilah S, Driever W. Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development (Cambridge, England). 123: 67-80. PMID 9007230  1
1996 Driever W, Solnica-Krezel L, Schier AF, Neuhauss SC, Malicki J, Stemple DL, Stainier DY, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C. A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123: 37-46. PMID 9007227  1
1996 Schier AF, Joyner AL, Lehmann R, Talbot WS. From screens to genes: prospects for insertional mutagenesis in zebrafish. Genes & Development. 10: 3077-80. PMID 8985177  1
1995 Andjelković M, Jones PF, Grossniklaus U, Cron P, Schier AF, Dick M, Bilbe G, Hemmings BA. Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase. The Journal of Biological Chemistry. 270: 4066-75. PMID 7876156 DOI: 10.1074/jbc.270.8.4066  1
1994 Gehring WJ, Qian YQ, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendez-Perez D, Affolter M, Otting G, Wüthrich K. Homeodomain-DNA recognition. Cell. 78: 211-23. PMID 8044836 DOI: 10.1016/0092-8674(94)90292-5  1
1994 Solnica-Krezel L, Schier AF, Driever W. Efficient recovery of ENU-induced mutations from the zebrafish germline. Genetics. 136: 1401-20. PMID 8013916  1
1993 Schier AF, Gehring WJ. Functional specificity of the homeodomain protein fushi tarazu: the role of DNA-binding specificity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 90: 1450-4. PMID 8434005  1
1993 Affolter M, Walldorf U, Kloter U, Schier AF, Gehring WJ. Regional repression of a Drosophila POU box gene in the endoderm involves inductive interactions between germ layers. Development (Cambridge, England). 117: 1199-210. PMID 8104774  1
1993 Schier AF, Gehring WJ. Analysis of a fushi tarazu autoregulatory element: multiple sequence elements contribute to enhancer activity. The Embo Journal. 12: 1111-9. PMID 8096173  1
1992 Schier AF, Gehring WJ. Direct homeodomain-DNA interaction in the autoregulation of the fushi tarazu gene. Nature. 356: 804-7. PMID 1574120 DOI: 10.1038/356804a0  1
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