Alexander Schier - Publications

1996-2005 Skirball Institute New York University School of Medicine, New York, NY, United States 
 2005- Harvard University, Cambridge, MA, United States 
Development, Sleep

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dingal PCDP, Carte AN, Montague TG, Lim Suan MB, Schier AF. Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1. Proceedings of the National Academy of Sciences of the United States of America. 120: e2307203120. PMID 37844219 DOI: 10.1073/pnas.2307203120  0.754
2022 Sfeir A, Fishell G, Schier AF, Dustin ML, Gan WB, Joyner A, Lehmann R, Ron D, Roth D, Talbot WS, Yelon D, Zychlinsky A. Basic science under threat: Lessons from the Skirball Institute. Cell. 185: 755-758. PMID 35245477 DOI: 10.1016/j.cell.2022.02.008  0.498
2020 Raj B, Farrell JA, Liu J, El Kholtei J, Carte AN, Navajas Acedo J, Du LY, McKenna A, Relić Đ, Leslie JM, Schier AF. Emergence of Neuronal Diversity during Vertebrate Brain Development. Neuron. PMID 33068532 DOI: 10.1016/j.neuron.2020.09.023  0.804
2020 Lin Q, Manley J, Helmreich M, Schlumm F, Li JM, Robson DN, Engert F, Schier A, Nöbauer T, Vaziri A. Cerebellar Neurodynamics Predict Decision Timing and Outcome on the Single-Trial Level. Cell. PMID 31955849 DOI: 10.1016/J.Cell.2019.12.018  0.768
2019 Ma 马漫修 M, Ramirez AD, Wang 王彤 T, Roberts RL, Harmon KE, Schoppik D, Sharma A, Kuang C, Goei SL, Gagnon JA, Zimmerman S, Tsai SQ, Reyon D, Joung JK, Aksay ERF, ... Schier AF, et al. Zebrafish Deficiency Impairs Retinal Patterning and Oculomotor Function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31685652 DOI: 10.1523/Jneurosci.1783-19.2019  0.8
2019 Haesemeyer M, Schier AF, Engert F. Convergent Temperature Representations in Artificial and Biological Neural Networks. Neuron. PMID 31376984 DOI: 10.1016/j.neuron.2019.07.003  0.57
2019 Wee CL, Nikitchenko M, Wang WC, Luks-Morgan SJ, Song E, Gagnon JA, Randlett O, Bianco IH, Lacoste AMB, Glushenkova E, Barrios JP, Schier AF, Kunes S, Engert F, Douglass AD. Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets. Nature Neuroscience. PMID 31358991 DOI: 10.1038/S41593-019-0452-X  0.79
2019 Randlett O, Haesemeyer M, Forkin G, Shoenhard H, Schier AF, Engert F, Granato M. Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish. Current Biology : Cb. PMID 30955936 DOI: 10.1016/J.Cub.2019.02.039  0.772
2019 Thyme SB, Pieper LM, Li EH, Pandey S, Wang Y, Morris NS, Sha C, Choi JW, Herrera KJ, Soucy ER, Zimmerman S, Randlett O, Greenwood J, McCarroll SA, Schier AF. Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Cell. PMID 30929901 DOI: 10.2139/ssrn.3198823  0.724
2018 Montague TG, Gagnon JA, Schier AF. Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse. Development (Cambridge, England). PMID 30446628 DOI: 10.1242/Dev.171090  0.796
2018 Raj B, Gagnon JA, Schier AF. Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT. Nature Protocols. PMID 30353175 DOI: 10.1038/S41596-018-0058-X  0.675
2018 Haesemeyer M, Robson DN, Li JM, Schier AF, Engert F. A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish. Neuron. 98: 817-831.e6. PMID 29731253 DOI: 10.1016/j.neuron.2018.04.013  0.775
2018 Rabani M, Pieper L, Chew GL, Schier AF. A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell. 70: 565. PMID 29727622 DOI: 10.1016/j.molcel.2018.04.013  0.484
2018 Raj B, Wagner DE, McKenna A, Pandey S, Klein AM, Shendure J, Gagnon JA, Schier AF. Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain. Nature Biotechnology. PMID 29608178 DOI: 10.1038/Nbt.4103  0.685
2017 Rabani M, Pieper L, Chew GL, Schier AF. A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation. Molecular Cell. PMID 29225039 DOI: 10.1016/J.Molcel.2017.11.014  0.528
2017 Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF. Nodal patterning without Lefty inhibitory feedback is functional but fragile. Elife. 6. PMID 29215332 DOI: 10.7554/Elife.28785  0.801
2017 Gagnon JA, Obbad K, Schier AF. Zebrafish nanog is primarily required in extraembryonic tissue. Development (Cambridge, England). PMID 29180571 DOI: 10.1242/Dev.147793  0.702
2017 Montague TG, Schier AF. Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm. Elife. 6. PMID 29140251 DOI: 10.7554/Elife.28183  0.774
2017 Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF. Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling. Elife. 6. PMID 29117894 DOI: 10.7554/Elife.22626  0.799
2017 Schoppik D, Bianco IH, Prober DA, Douglass AD, Robson DN, Li JMB, Greenwood JSF, Soucy E, Engert F, Schier AF. Gaze-stabilizing central vestibular neurons project asymmetrically to extraocular motoneuron pools. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28972121 DOI: 10.1523/Jneurosci.1711-17.2017  0.776
2017 Freyer L, Hsu CW, Nowotschin S, Pauli A, Ishida J, Kuba K, Fukamizu A, Schier AF, Hoodless PA, Dickinson ME, Hadjantonakis AK. Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives. Cell Reports. 20: 2116-2130. PMID 28854362 DOI: 10.1016/J.Celrep.2017.08.014  0.705
2017 Hildebrand DGC, Cicconet M, Torres RM, Choi W, Quan TM, Moon J, Wetzel AW, Scott Champion A, Graham BJ, Randlett O, Plummer GS, Portugues R, Bianco IH, Saalfeld S, Baden AD, ... ... Schier AF, et al. Whole-brain serial-section electron microscopy in larval zebrafish. Nature. PMID 28489821 DOI: 10.1038/Nature22356  0.779
2016 Thyme SB, Akhmetova L, Montague TG, Valen E, Schier AF. Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature Communications. 7: 11750. PMID 27282953 DOI: 10.1038/Ncomms11750  0.757
2016 McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J. Whole organism lineage tracing by combinatorial and cumulative genome editing. Science (New York, N.Y.). PMID 27229144 DOI: 10.1126/Science.Aaf7907  0.681
2016 Chew GL, Pauli A, Schier AF. Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish. Nature Communications. 7: 11663. PMID 27216465 DOI: 10.1038/ncomms11663  0.744
2016 Dunn TW, Mu Y, Narayan S, Randlett O, Naumann EA, Yang CT, Schier AF, Freeman J, Engert F, Ahrens MB. Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion. Elife. 5. PMID 27003593 DOI: 10.7554/Elife.12741  0.792
2016 Chiu CN, Rihel J, Lee DA, Singh C, Mosser EA, Chen S, Sapin V, Pham U, Engle J, Niles BJ, Montz CJ, Chakravarthy S, Zimmerman S, Salehi-Ashtiani K, Vidal M, ... Schier AF, et al. A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 89: 842-56. PMID 26889812 DOI: 10.1016/J.Neuron.2016.01.007  0.705
2015 Randlett O, Wee CL, Naumann EA, Nnaemeka O, Schoppik D, Fitzgerald JE, Portugues R, Lacoste AM, Riegler C, Engert F, Schier AF. Whole-brain activity mapping onto a zebrafish brain atlas. Nature Methods. 12: 1039-1046. PMID 26778924 DOI: 10.1038/Nmeth.3581  0.771
2015 Haesemeyer M, Robson DN, Li JM, Schier AF, Engert F. The structure and timescales of heat perception in larval zebrafish. Cell Systems. 1: 338-348. PMID 26640823 DOI: 10.1016/j.cels.2015.10.010  0.772
2015 Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. Plos One. 10: e0139504. PMID 26436892 DOI: 10.1371/Journal.Pone.0139504  0.784
2015 Lacoste AM, Schoppik D, Robson DN, Haesemeyer M, Portugues R, Li JM, Randlett O, Wee CL, Engert F, Schier AF. A convergent and essential interneuron pathway for mauthner-cell-mediated escapes. Current Biology : Cb. 25: 1526-34. PMID 25959971 DOI: 10.1016/J.Cub.2015.04.025  0.775
2015 Merkle FT, Neuhausser WM, Santos D, Valen E, Gagnon JA, Maas K, Sandoe J, Schier AF, Eggan K. Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus. Cell Reports. 11: 875-83. PMID 25937281 DOI: 10.1016/J.Celrep.2015.04.007  0.673
2015 Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142: 1113-24. PMID 25725064 DOI: 10.1242/Dev.117424  0.788
2015 Mundell NA, Beier KT, Pan YA, Lapan SW, Göz Aytürk D, Berezovskii VK, Wark AR, Drokhlyansky E, Bielecki J, Born RT, Schier AF, Cepko CL. Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. The Journal of Comparative Neurology. 523: 1639-63. PMID 25688551 DOI: 10.1002/Cne.23761  0.717
2015 Pauli A, Valen E, Schier AF. Identifying (non-)coding RNAs and small peptides: challenges and opportunities. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 103-12. PMID 25345765 DOI: 10.1002/bies.201400103  0.665
2014 Rabani M, Raychowdhury R, Jovanovic M, Rooney M, Stumpo DJ, Pauli A, Hacohen N, Schier AF, Blackshear PJ, Friedman N, Amit I, Regev A. High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell. 159: 1698-710. PMID 25497548 DOI: 10.1016/J.Cell.2014.11.015  0.67
2014 Richter C, Woods IG, Schier AF. Neuropeptidergic control of sleep and wakefulness. Annual Review of Neuroscience. 37: 503-31. PMID 25032501 DOI: 10.1146/Annurev-Neuro-062111-150447  0.647
2014 Gagnon JA, Valen E, Thyme SB, Huang P, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. Plos One. 9: e98186. PMID 24873830 DOI: 10.1371/Journal.Pone.0098186  0.783
2014 Woods IG, Schoppik D, Shi VJ, Zimmerman S, Coleman HA, Greenwood J, Soucy ER, Schier AF. Neuropeptidergic signaling partitions arousal behaviors in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3142-60. PMID 24573274 DOI: 10.1523/Jneurosci.3529-13.2014  0.795
2014 Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF. Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (New York, N.Y.). 343: 1248636. PMID 24407481 DOI: 10.1126/Science.1248636  0.796
2014 Zhang Y, Vastenhouw NL, Feng J, Fu K, Wang C, Ge Y, Pauli A, van Hummelen P, Schier AF, Liu XS. Canonical nucleosome organization at promoters forms during genome activation. Genome Research. 24: 260-6. PMID 24285721 DOI: 10.1101/gr.157750.113  0.663
2014 Blaser BW, Li B, Tamplin OJ, Binder V, Prober D, Schier A, Vidal M, Zon LI. Identification of Secreted Factors with a Role in Hematopoietic Stem and Progenitor Cell Engraftment in the Developing Zebrafish Blood. 124: 4361-4361. DOI: 10.1182/Blood.V124.21.4361.4361  0.69
2013 Pan YA, Freundlich T, Weissman TA, Schoppik D, Wang XC, Zimmerman S, Ciruna B, Sanes JR, Lichtman JW, Schier AF. Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (Cambridge, England). 140: 2835-46. PMID 23757414 DOI: 10.1242/Dev.094631  0.794
2013 Chew GL, Pauli A, Rinn JL, Regev A, Schier AF, Valen E. Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development (Cambridge, England). 140: 2828-34. PMID 23698349 DOI: 10.1242/Dev.098343  0.729
2013 Xiong F, Tentner AR, Huang P, Gelas A, Mosaliganti KR, Souhait L, Rannou N, Swinburne IA, Obholzer ND, Cowgill PD, Schier AF, Megason SG. Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell. 153: 550-61. PMID 23622240 DOI: 10.1016/J.Cell.2013.03.023  0.39
2013 Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16: 507-16. PMID 23455609 DOI: 10.1038/Nn.3346  0.658
2013 Varshney GK, Lu J, Gildea DE, Huang H, Pei W, Yang Z, Huang SC, Schoenfeld D, Pho NH, Casero D, Hirase T, Mosbrook-Davis D, Zhang S, Jao LE, Zhang B, ... ... Schier AF, et al. A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Research. 23: 727-35. PMID 23382537 DOI: 10.1101/Gr.151464.112  0.695
2012 Bianco IH, Ma LH, Schoppik D, Robson DN, Orger MB, Beck JC, Li JM, Schier AF, Engert F, Baker R. The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. Current Biology : Cb. 22: 1285-95. PMID 22704987 DOI: 10.1016/J.Cub.2012.05.026  0.769
2012 Huang P, Xiong F, Megason SG, Schier AF. Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord. Plos Genetics. 8: e1002762. PMID 22685423 DOI: 10.1371/Journal.Pgen.1002762  0.38
2012 Ahrens MB, Li JM, Orger MB, Robson DN, Schier AF, Engert F, Portugues R. Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature. 485: 471-7. PMID 22622571 DOI: 10.1038/Nature11057  0.791
2012 Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, ... ... Schier AF, et al. CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature Genetics. 44: 714-9. PMID 22581229 DOI: 10.1038/Ng.2277  0.79
2012 Müller P, Rogers KW, Jordan BM, Lee JS, Robson D, Ramanathan S, Schier AF. Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science (New York, N.Y.). 336: 721-4. PMID 22499809 DOI: 10.1126/Science.1221920  0.744
2012 Low SE, Woods IG, Lachance M, Ryan J, Schier AF, Saint-Amant L. Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of Neurophysiology. 108: 148-59. PMID 22490555 DOI: 10.1152/Jn.00839.2011  0.689
2012 Stooke-Vaughan GA, Huang P, Hammond KL, Schier AF, Whitfield TT. The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England). 139: 1777-87. PMID 22461562 DOI: 10.1242/dev.079947  0.369
2012 Pan YA, Caron SJ, Schier AF. BAPTI and BAPTISM birthdating of neurons in zebrafish. Cold Spring Harbor Protocols. 2012: 87-92. PMID 22194263 DOI: 10.1101/pdb.prot067520  0.784
2012 Pan YA, Choy M, Prober DA, Schier AF. Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development (Cambridge, England). 139: 591-600. PMID 22190641 DOI: 10.1242/Dev.076588  0.79
2012 Pauli A, Valen E, Lin MF, Garber M, Vastenhouw NL, Levin JZ, Fan L, Sandelin A, Rinn JL, Regev A, Schier AF. Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. Genome Research. 22: 577-91. PMID 22110045 DOI: 10.1101/gr.133009.111  0.695
2012 Stooke-Vaughan G, Huang P, Hammond K, Schier A, Whitfield T. The role of cilia and ciliary motility in otolith formation in the zebrafish embryo Cilia. 1: 78. DOI: 10.1186/2046-2530-1-S1-P78  0.339
2011 Pauli A, Rinn JL, Schier AF. Non-coding RNAs as regulators of embryogenesis. Nature Reviews. Genetics. 12: 136-49. PMID 21245830 DOI: 10.1038/nrg2904  0.692
2011 Pan YA, Livet J, Sanes JR, Lichtman JW, Schier AF. Multicolor Brainbow imaging in zebrafish. Cold Spring Harbor Protocols. 2011: pdb.prot5546. PMID 21205846 DOI: 10.1101/pdb.prot5546  0.742
2010 Rihel J, Prober DA, Schier AF. Monitoring sleep and arousal in zebrafish. Methods in Cell Biology. 100: 281-94. PMID 21111222 DOI: 10.1016/B978-0-12-384892-5.00011-6  0.595
2010 Vastenhouw NL, Zhang Y, Woods IG, Imam F, Regev A, Liu XS, Rinn J, Schier AF. Chromatin signature of embryonic pluripotency is established during genome activation. Nature. 464: 922-6. PMID 20336069 DOI: 10.1038/Nature08866  0.688
2010 Naumann EA, Kampff AR, Prober DA, Schier AF, Engert F. Monitoring neural activity with bioluminescence during natural behavior. Nature Neuroscience. 13: 513-20. PMID 20305645 DOI: 10.1038/Nn.2518  0.762
2010 Rihel J, Prober DA, Arvanites A, Lam K, Zimmerman S, Jang S, Haggarty SJ, Kokel D, Rubin LL, Peterson RT, Schier AF. Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science (New York, N.Y.). 327: 348-51. PMID 20075256 DOI: 10.1126/Science.1183090  0.623
2009 Huang P, Schier AF. Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England). 136: 3089-98. PMID 19700616 DOI: 10.1242/dev.041343  0.406
2008 Prober DA, Zimmerman S, Myers BR, McDermott BM, Kim SH, Caron S, Rihel J, Solnica-Krezel L, Julius D, Hudspeth AJ, Schier AF. Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10102-10. PMID 18829968 DOI: 10.1523/Jneurosci.2740-08.2008  0.789
2008 Caron SJ, Prober D, Choy M, Schier AF. In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development (Cambridge, England). 135: 3259-69. PMID 18755773 DOI: 10.1242/Dev.023200  0.786
2008 Douglass AD, Kraves S, Deisseroth K, Schier AF, Engert F. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current Biology : Cb. 18: 1133-7. PMID 18682213 DOI: 10.1016/J.Cub.2008.06.077  0.616
2008 Woods IG, Schier AF. Targeted mutagenesis in zebrafish. Nature Biotechnology. 26: 650-1. PMID 18536686 DOI: 10.1038/Nbt0608-650  0.687
2008 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz HR, Schier AF, Dulac C. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 57: 41-55. PMID 18184563 DOI: 10.1016/J.Neuron.2007.11.018  0.769
2008 Schier A. Regulation of nodal signaling Developmental Biology. 319: 473. DOI: 10.1016/J.YDBIO.2008.05.030  0.301
2007 Bennett JT, Stickney HL, Choi WY, Ciruna B, Talbot WS, Schier AF. Maternal nodal and zebrafish embryogenesis. Nature. 450: E1-2; discussion E2-. PMID 17994032 DOI: 10.1038/Nature06314  0.734
2007 Karkera JD, Lee JS, Roessler E, Banerjee-Basu S, Ouspenskaia MV, Mez J, Goldmuntz E, Bowers P, Towbin J, Belmont JW, Baxevanis AD, Schier AF, Muenke M. Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. American Journal of Human Genetics. 81: 987-94. PMID 17924340 DOI: 10.1086/522890  0.39
2007 Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science (New York, N.Y.). 318: 271-4. PMID 17761850 DOI: 10.1126/Science.1147535  0.641
2007 Bennett JT, Joubin K, Cheng S, Aanstad P, Herwig R, Clark M, Lehrach H, Schier AF. Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental Biology. 304: 525-40. PMID 17306247 DOI: 10.1016/J.Ydbio.2007.01.012  0.671
2006 Schier AF, Giraldez AJ. MicroRNA function and mechanism: insights from zebra fish. Cold Spring Harbor Symposia On Quantitative Biology. 71: 195-203. PMID 17381297 DOI: 10.1101/sqb.2006.71.055  0.53
2006 Prober DA, Rihel J, Onah AA, Sung RJ, Schier AF. Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13400-10. PMID 17182791 DOI: 10.1523/Jneurosci.4332-06.2006  0.626
2006 Mishima Y, Giraldez AJ, Takeda Y, Fujiwara T, Sakamoto H, Schier AF, Inoue K. Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Current Biology : Cb. 16: 2135-42. PMID 17084698 DOI: 10.1016/J.Cub.2006.08.086  0.775
2006 Obara T, Mangos S, Liu Y, Zhao J, Wiessner S, Kramer-Zucker AG, Olale F, Schier AF, Drummond IA. Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology : Jasn. 17: 2706-18. PMID 16943304 DOI: 10.1681/Asn.2006040412  0.793
2006 Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, Inoue K, Enright AJ, Schier AF. Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science (New York, N.Y.). 312: 75-9. PMID 16484454 DOI: 10.1126/Science.1122689  0.764
2006 Ciruna B, Jenny A, Lee D, Mlodzik M, Schier AF. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature. 439: 220-4. PMID 16407953 DOI: 10.1038/Nature04375  0.449
2005 Schier AF, Talbot WS. Molecular genetics of axis formation in zebrafish. Annual Review of Genetics. 39: 561-613. PMID 16285872 DOI: 10.1146/annurev.genet.37.110801.143752  0.62
2005 Kramer-Zucker AG, Olale F, Haycraft CJ, Yoder BK, Schier AF, Drummond IA. Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (Cambridge, England). 132: 1907-21. PMID 15790966 DOI: 10.1242/Dev.01772  0.773
2005 Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson JM, Baskerville S, Hammond SM, Bartel DP, Schier AF. MicroRNAs regulate brain morphogenesis in zebrafish. Science (New York, N.Y.). 308: 833-8. PMID 15774722 DOI: 10.1126/Science.1109020  0.539
2005 Dutta S, Dietrich JE, Aspöck G, Burdine RD, Schier A, Westerfield M, Varga ZM. pitx3 defines an equivalence domain for lens and anterior pituitary placode. Development (Cambridge, England). 132: 1579-90. PMID 15728669 DOI: 10.1242/Dev.01723  0.738
2005 Le Good JA, Joubin K, Giraldez AJ, Ben-Haim N, Beck S, Chen Y, Schier AF, Constam DB. Nodal stability determines signaling range. Current Biology : Cb. 15: 31-6. PMID 15649361 DOI: 10.1016/j.cub.2004.12.062  0.574
2005 Tyurina OV, Guner B, Popova E, Feng J, Schier AF, Kohtz JD, Karlstrom RO. Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental Biology. 277: 537-56. PMID 15617692 DOI: 10.1016/J.Ydbio.2004.10.003  0.811
2004 Cheng SK, Olale F, Brivanlou AH, Schier AF. Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. Plos Biology. 2: E30. PMID 14966532 DOI: 10.1371/Journal.Pbio.0020030  0.787
2003 Kunwar PS, Zimmerman S, Bennett JT, Chen Y, Whitman M, Schier AF. Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development (Cambridge, England). 130: 5589-99. PMID 14522874 DOI: 10.1242/Dev.00803  0.509
2003 Dougan ST, Warga RM, Kane DA, Schier AF, Talbot WS. The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development (Cambridge, England). 130: 1837-51. PMID 12642489 DOI: 10.1242/Dev.00400  0.641
2003 Karlstrom RO, Tyurina OV, Kawakami A, Nishioka N, Talbot WS, Sasaki H, Schier AF. Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development (Cambridge, England). 130: 1549-64. PMID 12620981 DOI: 10.1242/Dev.00364  0.811
2003 Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF. EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes & Development. 17: 31-6. PMID 12514096 DOI: 10.1101/Gad.1041203  0.774
2002 de la Cruz JM, Bamford RN, Burdine RD, Roessler E, Barkovich AJ, Donnai D, Schier AF, Muenke M. A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human Genetics. 110: 422-8. PMID 12073012 DOI: 10.1007/S00439-002-0709-3  0.622
2002 Yamashita S, Miyagi C, Carmany-Rampey A, Shimizu T, Fujii R, Schier AF, Hirano T. Stat3 Controls Cell Movements during Zebrafish Gastrulation. Developmental Cell. 2: 363-75. PMID 11879641 DOI: 10.1016/S1534-5807(02)00126-0  0.794
2001 Carmany-Rampey A, Schier AF. Single-cell internalization during zebrafish gastrulation. Current Biology : Cb. 11: 1261-5. PMID 11525740 DOI: 10.1016/S0960-9822(01)00353-0  0.799
2000 Concha ML, Burdine RD, Russell C, Schier AF, Wilson SW. A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. Neuron. 28: 399-409. PMID 11144351 DOI: 10.1016/S0896-6273(00)00120-3  0.641
2000 Bamford RN, Roessler E, Burdine RD, SaplakoÄŸlu U, dela Cruz J, Splitt M, Goodship JA, Towbin J, Bowers P, Ferrero GB, Marino B, Schier AF, Shen MM, Muenke M, Casey B. Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects. Nature Genetics. 26: 365-9. PMID 11062482 DOI: 10.1038/81695  0.624
2000 Sirotkin HI, Gates MA, Kelly PD, Schier AF, Talbot WS. Fast1 is required for the development of dorsal axial structures in zebrafish. Current Biology : Cb. 10: 1051-4. PMID 10996072 DOI: 10.1016/S0960-9822(00)00679-5  0.622
2000 Sirotkin HI, Dougan ST, Schier AF, Talbot WS. bozozok and squint act in parallel to specify dorsal mesoderm and anterior neuroectoderm in zebrafish. Development (Cambridge, England). 127: 2583-92. PMID 10821757  0.305
2000 Feldman B, Dougan ST, Schier AF, Talbot WS. Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish. Current Biology : Cb. 10: 531-4. PMID 10801442 DOI: 10.1016/S0960-9822(00)00469-3  0.634
2000 Kelly PD, Chu F, Woods IG, Ngo-Hazelett P, Cardozo T, Huang H, Kimm F, Liao L, Yan YL, Zhou Y, Johnson SL, Abagyan R, Schier AF, Postlethwait JH, Talbot WS. Genetic linkage mapping of zebrafish genes and ESTs. Genome Research. 10: 558-67. PMID 10779498 DOI: 10.1101/Gr.10.4.558  0.758
2000 Burdine RD, Schier AF. Conserved and divergent mechanisms in left-right axis formation. Genes & Development. 14: 763-76. PMID 10766733 DOI: 10.1101/Gad.14.7.763  0.559
2000 Gritsman K, Talbot WS, Schier AF. Nodal signaling patterns the organizer. Development (Cambridge, England). 127: 921-32. PMID 10662632  0.663
1999 Yan YT, Gritsman K, Ding J, Burdine RD, Corrales JD, Price SM, Talbot WS, Schier AF, Shen MM. Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes & Development. 13: 2527-37. PMID 10521397 DOI: 10.1101/Gad.13.19.2527  0.784
1999 Meno C, Gritsman K, Ohishi S, Ohfuji Y, Heckscher E, Mochida K, Shimono A, Kondoh H, Talbot WS, Robertson EJ, Schier AF, Hamada H. Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Molecular Cell. 4: 287-98. PMID 10518210 DOI: 10.1016/S1097-2765(00)80331-7  0.759
1999 Geisler R, Rauch GJ, Baier H, van Bebber F, Bross L, Dekens MP, Finger K, Fricke C, Gates MA, Geiger H, Geiger-Rudolph S, Gilmour D, Glaser S, Gnügge L, Habeck H, ... ... Schier AF, et al. A radiation hybrid map of the zebrafish genome. Nature Genetics. 23: 86-9. PMID 10471505 DOI: 10.1038/12692  0.751
1999 Gates MA, Kim L, Egan ES, Cardozo T, Sirotkin HI, Dougan ST, Lashkari D, Abagyan R, Schier AF, Talbot WS. A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Genome Research. 9: 334-47. PMID 10207156 DOI: 10.1101/Gr.9.4.334  0.571
1999 Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell. 97: 121-32. PMID 10199408 DOI: 10.1016/S0092-8674(00)80720-5  0.812
1999 Fekany K, Yamanaka Y, Leung T, Sirotkin HI, Topczewski J, Gates MA, Hibi M, Renucci A, Stemple D, Radbill A, Schier AF, Driever W, Hirano T, Talbot WS, Solnica-Krezel L. The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development (Cambridge, England). 126: 1427-38. PMID 10068636  0.585
1999 Karlstrom RO, Talbot WS, Schier AF. Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes & Development. 13: 388-93. PMID 10049354 DOI: 10.1101/Gad.13.4.388  0.767
1999 Talbot WS, Schier AF. Positional cloning of mutated zebrafish genes. Methods in Cell Biology. 60: 259-86. PMID 9891342 DOI: 10.1016/S0091-679X(08)61905-6  0.563
1998 Drummond IA, Majumdar A, Hentschel H, Elger M, Solnica-Krezel L, Schier AF, Neuhauss SC, Stemple DL, Zwartkruis F, Rangini Z, Driever W, Fishman MC. Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (Cambridge, England). 125: 4655-67. PMID 9806915  0.713
1998 Feldman B, Gates MA, Egan ES, Dougan ST, Rennebeck G, Sirotkin HI, Schier AF, Talbot WS. Zebrafish organizer development and germ-layer formation require nodal-related signals. Nature. 395: 181-5. PMID 9744277 DOI: 10.1038/26013  0.609
1998 Schier AF, Talbot WS. The zebrafish organizer. Current Opinion in Genetics & Development. 8: 464-71. PMID 9729724 DOI: 10.1016/S0959-437X(98)80119-6  0.596
1998 Zhang J, Talbot WS, Schier AF. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell. 92: 241-51. PMID 9458048 DOI: 10.1016/S0092-8674(00)80918-6  0.611
1997 Schier AF, Neuhauss SC, Helde KA, Talbot WS, Driever W. The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development (Cambridge, England). 124: 327-42. PMID 9053309 DOI: 10.5167/Uzh-231  0.73
1996 Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Abdelilah S, Stainier DY, Driever W. Mutations affecting craniofacial development in zebrafish. Development (Cambridge, England). 123: 357-67. PMID 9007255 DOI: 10.5167/Uzh-228  0.703
1996 Pack M, Solnica-Krezel L, Malicki J, Neuhauss SC, Schier AF, Stemple DL, Driever W, Fishman MC. Mutations affecting development of zebrafish digestive organs. Development (Cambridge, England). 123: 321-8. PMID 9007252 DOI: 10.5167/Uzh-229  0.697
1996 Weinstein BM, Schier AF, Abdelilah S, Malicki J, Solnica-Krezel L, Stemple DL, Stainier DY, Zwartkruis F, Driever W, Fishman MC. Hematopoietic mutations in the zebrafish. Development (Cambridge, England). 123: 303-9. PMID 9007250  0.557
1996 Stainier DY, Fouquet B, Chen JN, Warren KS, Weinstein BM, Meiler SE, Mohideen MA, Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W, Fishman MC. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123: 285-92. PMID 9007248 DOI: 10.5167/Uzh-237  0.692
1996 Malicki J, Schier AF, Solnica-Krezel L, Stemple DL, Neuhauss SC, Stainier DY, Abdelilah S, Rangini Z, Zwartkruis F, Driever W. Mutations affecting development of the zebrafish ear. Development (Cambridge, England). 123: 275-83. PMID 9007247  0.713
1996 Malicki J, Neuhauss SC, Schier AF, Solnica-Krezel L, Stemple DL, Stainier DY, Abdelilah S, Zwartkruis F, Rangini Z, Driever W. Mutations affecting development of the zebrafish retina. Development (Cambridge, England). 123: 263-73. PMID 9007246  0.687
1996 Abdelilah S, Mountcastle-Shah E, Harvey M, Solnica-Krezel L, Schier AF, Stemple DL, Malicki J, Neuhauss SC, Zwartkruis F, Stainier DY, Rangini Z, Driever W. Mutations affecting neural survival in the zebrafish Danio rerio. Development (Cambridge, England). 123: 217-27. PMID 9007242  0.704
1996 Schier AF, Neuhauss SC, Harvey M, Malicki J, Solnica-Krezel L, Stainier DY, Zwartkruis F, Abdelilah S, Stemple DL, Rangini Z, Yang H, Driever W. Mutations affecting the development of the embryonic zebrafish brain. Development (Cambridge, England). 123: 165-78. PMID 9007238 DOI: 10.5167/Uzh-232  0.716
1996 Stemple DL, Solnica-Krezel L, Zwartkruis F, Neuhauss SC, Schier AF, Malicki J, Stainier DY, Abdelilah S, Rangini Z, Mountcastle-Shah E, Driever W. Mutations affecting development of the notochord in zebrafish. Development (Cambridge, England). 123: 117-28. PMID 9007234 DOI: 10.5167/Uzh-238  0.717
1996 Solnica-Krezel L, Stemple DL, Mountcastle-Shah E, Rangini Z, Neuhauss SC, Malicki J, Schier AF, Stainier DY, Zwartkruis F, Abdelilah S, Driever W. Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development (Cambridge, England). 123: 67-80. PMID 9007230  0.706
1996 Driever W, Solnica-Krezel L, Schier AF, Neuhauss SC, Malicki J, Stemple DL, Stainier DY, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C. A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123: 37-46. PMID 9007227 DOI: 10.5167/Uzh-215  0.698
1996 Schier AF, Joyner AL, Lehmann R, Talbot WS. From screens to genes: prospects for insertional mutagenesis in zebrafish. Genes & Development. 10: 3077-80. PMID 8985177 DOI: 10.1101/GAD.10.24.3077  0.55
1995 Andjelković M, Jones PF, Grossniklaus U, Cron P, Schier AF, Dick M, Bilbe G, Hemmings BA. Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase. The Journal of Biological Chemistry. 270: 4066-75. PMID 7876156 DOI: 10.1074/Jbc.270.8.4066  0.523
1994 Gehring WJ, Qian YQ, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendez-Perez D, Affolter M, Otting G, Wüthrich K. Homeodomain-DNA recognition. Cell. 78: 211-23. PMID 8044836 DOI: 10.1016/0092-8674(94)90292-5  0.731
1994 Driever W, Stemple D, Schier A, Solnica-Krezel L. Zebrafish: genetic tools for studying vertebrate development. Trends in Genetics : Tig. 10: 152-9. PMID 8036717 DOI: 10.1016/0168-9525(94)90091-4  0.574
1994 Solnica-Krezel L, Schier AF, Driever W. Efficient recovery of ENU-induced mutations from the zebrafish germline. Genetics. 136: 1401-20. PMID 8013916  0.531
1993 Schier AF, Gehring WJ. Functional specificity of the homeodomain protein fushi tarazu: the role of DNA-binding specificity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 90: 1450-4. PMID 8434005  0.456
1993 Affolter M, Walldorf U, Kloter U, Schier AF, Gehring WJ. Regional repression of a Drosophila POU box gene in the endoderm involves inductive interactions between germ layers. Development (Cambridge, England). 117: 1199-210. PMID 8104774  0.632
1993 Schier AF, Gehring WJ. Analysis of a fushi tarazu autoregulatory element: multiple sequence elements contribute to enhancer activity. The Embo Journal. 12: 1111-9. PMID 8096173  0.456
1992 Schier AF, Gehring WJ. Direct homeodomain-DNA interaction in the autoregulation of the fushi tarazu gene. Nature. 356: 804-7. PMID 1574120 DOI: 10.1038/356804a0  0.475
1990 Pick L, Schier A, Affolter M, Schmidt-Glenewinkel T, Gehring WJ. Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated. Genes & Development. 4: 1224-39. PMID 1976571 DOI: 10.1101/GAD.4.7.1224  0.641
1990 Gibson G, Schier A, LeMotte P, Gehring WJ. The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell. 62: 1087-103. PMID 1976044 DOI: 10.1016/0092-8674(90)90386-S  0.623
1990 Affolter M, Schier A, Gehring WJ. Homeodomain proteins and the regulation of gene expression. Current Opinion in Cell Biology. 2: 485-95. PMID 1974141 DOI: 10.1016/0955-0674(90)90132-X  0.631
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