Justin Guinney, Ph.D. - Publications

Computational Biology and Bioinformatics Duke University, Durham, NC 
Computational biology , statistical learning , Laplacian statistics

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kattan MW, Hess KR, Amin MB, Lu Y, Moons KG, Gershenwald JE, Gimotty PA, Guinney JH, Halabi S, Lazar AJ, Mahar AL, Patel T, Sargent DJ, Weiser MR, Compton C, et al. American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine. Ca: a Cancer Journal For Clinicians. PMID 26784705 DOI: 10.3322/caac.21339  1
2015 Guinney J, Dienstmann R, Wang X, de Reyniès A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot BM, Morris JS, Simon IM, Gerster S, Fessler E, et al. The consensus molecular subtypes of colorectal cancer. Nature Medicine. PMID 26457759 DOI: 10.1038/nm.3967  1
2015 Paten B, Diekhans M, Druker BJ, Friend S, Guinney J, Gassner N, Guttman M, James Kent W, Mantey P, Margolin AA, Massie M, Novak AM, Nothaft F, Pachter L, Patterson D, et al. The NIH BD2K center for big data in translational genomics. Journal of the American Medical Informatics Association : Jamia. PMID 26174866 DOI: 10.1093/jamia/ocv047  1
2015 Dienstmann R, Jang IS, Bot B, Friend S, Guinney J. Database of genomic biomarkers for cancer drugs and clinical targetability in solid tumors. Cancer Discovery. 5: 118-23. PMID 25656898 DOI: 10.1158/2159-8290.CD-14-1118  1
2015 Sinicrope FA, Shi Q, Smyrk TC, Thibodeau SN, Dienstmann R, Guinney J, Bot BM, Tejpar S, Delorenzi M, Goldberg RM, Mahoney M, Sargent DJ, Alberts SR. Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes. Gastroenterology. 148: 88-99. PMID 25305506 DOI: 10.1053/j.gastro.2014.09.041  1
2014 Kemp CJ, Moore JM, Moser R, Bernard B, Teater M, Smith LE, Rabaia NA, Gurley KE, Guinney J, Busch SE, Shaknovich R, Lobanenkov VV, Liggitt D, Shmulevich I, Melnick A, et al. CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer. Cell Reports. 7: 1020-9. PMID 24794443 DOI: 10.1016/j.celrep.2014.04.004  1
2014 Jang IS, Neto EC, Guinney J, Friend SH, Margolin AA. Systematic assessment of analytical methods for drug sensitivity prediction from cancer cell line data. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 63-74. PMID 24297534  1
2014 Guinney J, Ferté C, Dry J, McEwen R, Manceau G, Kao KJ, Chang KM, Bendtsen C, Hudson K, Huang E, Dougherty B, Ducreux M, Soria JC, Friend S, Derry J, et al. Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 265-72. PMID 24170544 DOI: 10.1158/1078-0432.CCR-13-1943  1
2013 Ferté C, Trister AD, Huang E, Bot BM, Guinney J, Commo F, Sieberts S, André F, Besse B, Soria JC, Friend SH. Impact of bioinformatic procedures in the development and translation of high-throughput molecular classifiers in oncology. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4315-25. PMID 23780890 DOI: 10.1158/1078-0432.CCR-12-3937  1
2013 Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, et al. Improving breast cancer survival analysis through competition-based multidimensional modeling. Plos Computational Biology. 9: e1003047. PMID 23671412 DOI: 10.1371/journal.pcbi.1003047  1
2013 Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, et al. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer. Science Translational Medicine. 5: 181re1. PMID 23596205 DOI: 10.1126/scitranslmed.3006112  1
2013 Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan JB, Gao Y, Deconde R, Chen M, Rajapakse I, Friend S, Ideker T, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Molecular Cell. 49: 359-67. PMID 23177740 DOI: 10.1016/j.molcel.2012.10.016  1
2012 Xu X, Rock JR, Lu Y, Futtner C, Schwab B, Guinney J, Hogan BLM, Onaitis MW. Evidence for type II cells as cells of origin of K-Ras - Induced distal lung adenocarcinoma Proceedings of the National Academy of Sciences of the United States of America. 109: 4910-4915. PMID 22411819 DOI: 10.1073/pnas.1112499109  1
2011 Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, ... ... Guinney J, et al. Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting. Plos One. 6: e20090. PMID 21750698 DOI: 10.1371/journal.pone.0020090  1
2011 Onaitis M, D'Amico TA, Clark CP, Guinney J, Harpole DH, Rawlins EL. A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma. The Annals of Thoracic Surgery. 91: 1046-50; discussion . PMID 21353202 DOI: 10.1016/j.athoracsur.2010.12.054  1
2011 Guinney J, Wu Q, Mukherjee S. Estimating variable structure and dependence in multitask learning via gradients Machine Learning. 83: 265-287. DOI: 10.1007/s10994-010-5217-4  1
2009 Mendiratta P, Mostaghel E, Guinney J, Tewari AK, Porrello A, Barry WT, Nelson PS, Febbo PG. Genomic strategy for targeting therapy in castration-resistant prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2022-9. PMID 19289629 DOI: 10.1200/JCO.2008.17.2882  1
2008 Mendiratta P, Tewari A, Guinney J, Porrello A, Barry WT, Febbo PG. A genomic strategy for targeting therapy in castration-Independent Prostate Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 5067. PMID 27948753 DOI: 10.1200/jco.2008.26.15_suppl.5067  0.48
2008 Boyle AP, Guinney J, Crawford GE, Furey TS. F-Seq: a feature density estimator for high-throughput sequence tags. Bioinformatics (Oxford, England). 24: 2537-8. PMID 18784119 DOI: 10.1093/bioinformatics/btn480  1
2008 Edelman EJ, Guinney J, Chi JT, Febbo PG, Mukherjee S. Modeling cancer progression via pathway dependencies. Plos Computational Biology. 4: e28. PMID 18282083 DOI: 10.1371/journal.pcbi.0040028  1
2006 Edelman E, Porrello A, Guinney J, Balakumaran B, Bild A, Febbo PG, Mukherjee S. Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles. Bioinformatics (Oxford, England). 22: e108-16. PMID 16873460 DOI: 10.1093/bioinformatics/btl231  1
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