Justin Guinney, Ph.D. - Publications

Affiliations: 
Computational Biology and Bioinformatics Duke University, Durham, NC 
Area:
Computational biology , statistical learning , Laplacian statistics

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pollard K, Banerjee J, Doan X, Wang J, Guo X, Allaway R, Langmead S, Slobogean B, Meyer CF, Loeb DM, Morris CD, Belzberg AJ, Blakeley JO, Rodriguez FJ, Guinney J, et al. A clinically and genomically annotated nerve sheath tumor biospecimen repository. Scientific Data. 7: 184. PMID 32561749 DOI: 10.1038/S41597-020-0508-5  0.34
2020 Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, ... ... Guinney J, et al. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell. 181: 236-249. PMID 32302568 DOI: 10.1016/J.Cell.2020.03.053  0.321
2020 Banerjee J, Allaway RJ, Taroni JN, Baker A, Zhang X, Moon CI, Pratilas CA, Blakeley JO, Guinney J, Hirbe A, Greene CS, Gosline SJ. Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1. Genes. 11. PMID 32098059 DOI: 10.3390/Genes11020226  0.347
2020 Mason MJ, Schinke C, Eng CLP, Towfic F, Gruber F, Dervan A, White BS, Pratapa A, Guan Y, Chen H, Cui Y, Li B, Yu T, Chaibub Neto E, Mavrommatis K, ... ... Guinney J, et al. Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease. Leukemia. PMID 32060406 DOI: 10.1038/S41375-020-0742-Z  0.375
2020 Eddy JA, Thorsson V, Lamb AE, Gibbs DL, Heimann C, Yu JX, Chung V, Chae Y, Dang K, Vincent BG, Shmulevich I, Guinney J. CRI iAtlas: an interactive portal for immuno-oncology research F1000research. 9: 1028. DOI: 10.12688/F1000Research.25141.1  0.362
2020 Chen Z, Mo J, Brosseau J, Shipman T, Wang Y, Liao C, Cooper JM, Allaway RJ, Gosline SJC, Guinney J, Carroll TJ, Le LQ. Abstract B23: A novel model of neurofibroma that deciphers its developmental origin and susceptibility to modification by the Hippo pathway Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-B23  0.384
2019 Dienstmann R, Villacampa G, Sveen A, Mason MJ, Niedzwiecki D, Nesbakken A, Moreno V, Warren RS, Lothe RA, Guinney J. Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 31504112 DOI: 10.1093/Annonc/Mdz287  0.353
2019 Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, ... ... Guinney J, et al. The Immune Landscape of Cancer. Immunity. 51: 411-412. PMID 31433971 DOI: 10.1016/J.Immuni.2019.08.004  0.327
2019 Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M, Jang IS, Ghazoui Z, ... ... Guinney J, et al. Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications. 10: 2674. PMID 31209238 DOI: 10.1038/S41467-019-09799-2  0.394
2019 Gosline SJC, Allaway R, Guinney J. DTEN: a network-based workflow to identify drug target networks from gene expression data in rare disease F1000research. 8. DOI: 10.7490/F1000Research.1117232.1  0.303
2019 Mason MJ, Schinke CD, Eng C, Towfic F, Gruber F, White BS, Cui Y, Li B, Yu T, Dalton WS, Goldschmidt H, Avet-Loiseau H, Samur M, Ortiz M, Trotter M, ... ... Guinney J, et al. Crowdsourced High-Risk Classifiers for Multiple Myeloma Patients Commonly Identify PHF19 As a Robust Progression Biomarker Blood. 134: 4370-4370. DOI: 10.1182/Blood-2019-127362  0.316
2019 Thorsson V, Eddy JA, Lamb A, Gibbs DL, Shmulevich I, Guinney J. Abstract B051: Facilitating translational research with interactive tools for immuno-oncology data Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B051  0.393
2019 White BS, Gentles AJ, Reyniès Ad, Newman AM, Lamb A, Heiser L, Waterfall JJ, Yu T, Guinney J. Abstract 1690: A tumor deconvolution DREAM Challenge: Inferring immune infiltration from bulk gene expression data Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1690  0.334
2018 Chang K, Willis JA, Reumers J, Taggart MW, San Lucas FA, Thirumurthi S, Kanth P, Delker DA, Hagedorn CH, Lynch PM, Ellis LM, Hawk ET, Scheet PA, Kopetz S, Arts J, ... Guinney J, et al. Colorectal premalignancy is associated with consensus molecular subtypes 1 and 2. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: 2061-2067. PMID 30412224 DOI: 10.1093/Annonc/Mdy337  0.375
2018 Lee AY, Ewing AD, Ellrott K, Hu Y, Houlahan KE, Bare JC, Espiritu SMG, Huang V, Dang K, Chong Z, Caloian C, Yamaguchi TN, Kellen MR, Chen K, ... ... Guinney J, et al. Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection. Genome Biology. 19: 188. PMID 30400818 DOI: 10.1186/S13059-018-1539-5  0.361
2018 Chen Z, Mo J, Brosseau JP, Shipman T, Wang Y, Liao CP, Cooper JM, Allaway RJ, Gosline SJC, Guinney J, Carroll TJ, Le LQ. Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway. Cancer Discovery. PMID 30348677 DOI: 10.1158/2159-8290.Cd-18-0151  0.35
2018 Allaway R, Angus SP, Beauchamp RL, Blakeley JO, Bott M, Burns SS, Carlstedt A, Chang LS, Chen X, Clapp DW, Desouza PA, Erdin S, Fernandez-Valle C, Guinney J, et al. Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2. Plos One. 13: e0197350. PMID 29897904 DOI: 10.1371/Journal.Pone.0197350  0.356
2018 Ferrer M, Gosline SJC, Stathis M, Zhang X, Guo X, Guha R, Ryman DA, Wallace MR, Kasch-Semenza L, Hao H, Ingersoll R, Mohr D, Thomas C, Verma S, Guinney J, et al. Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells. Scientific Data. 5: 180106. PMID 29893754 DOI: 10.1038/Sdata.2018.106  0.342
2018 Allaway RJ, Gosline SJC, La Rosa S, Knight P, Bakker A, Guinney J, Le LQ. Cutaneous neurofibromas in the genomics era: current understanding and open questions. British Journal of Cancer. PMID 29695767 DOI: 10.1038/S41416-018-0073-2  0.375
2018 Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, ... ... Guinney J, et al. The Immune Landscape of Cancer. Immunity. PMID 29628290 DOI: 10.1016/J.Immuni.2018.03.023  0.398
2018 Xu C, Nikolova O, Basom R, Mitchell RM, Shaw R, Moser R, Park H, Gurley KE, Kao M, Green CL, Schaub FX, Diaz RL, Swan HA, Jang IS, Guinney J, et al. Functional precision medicine identifies novel druggable targets and therapeutic options in head and neck cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29599409 DOI: 10.1158/1078-0432.Ccr-17-1339  0.359
2018 White BS, Khan SA, Ammad-ud-din M, Potdar S, Mason MJ, Tognon CE, Druker BJ, Heckman CA, Kallioniemi O, Kurtz SE, Porkka K, Tyner JW, Aittokallio T, Wennerberg K, Guinney J. Comparative Analysis of Independent Ex Vivo functional Drug Screens Identifies Predictive Biomarkers of BCL-2 Inhibitor Response in AML Blood. 132: 2763-2763. DOI: 10.1182/Blood-2018-99-111916  0.34
2018 Allaway RJ, Gosline SJ, Nievo M, Rosa SL, Bakker A, Guinney J. Abstract 4643: Drug-Target Explorer: An interactive tool for examining chemical-biological interactions Cancer Research. 78: 4643-4643. DOI: 10.1158/1538-7445.Am2018-4643  0.334
2018 Dry JR, Menden MP, Bulusu K, Guinney J, Saez-Rodriguez J. Abstract 3886: A large cancer pharmacogenomics combination screen powering crowd-sourced advancement of computational drug synergy predictions Cancer Research. 78: 3886-3886. DOI: 10.1158/1538-7445.Am2018-3886  0.356
2018 White BS, Khan SA, Ammad-ud-din M, Potdar S, Mason MJ, Tognon CE, Druker BJ, Heckman CA, Kallioniemi OP, Kurtz SE, Porkka K, Tyner JW, Aittokallio T, Wennerberg K, Guinney J. Abstract 3883: Gene expression predicts ex vivo drug sensitivity in acute myeloid leukemia Cancer Research. 78: 3883-3883. DOI: 10.1158/1538-7445.Am2018-3883  0.375
2018 Dry JR, Menden M, Rodriguez JS, Guinney J. Abstract B076: A DREAM-world of approaches for predicting combination synergies in cancer Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B076  0.422
2017 Sveen A, Bruun J, Eide PW, Eilertsen IA, Ramirez L, Murumägi A, Arjama MA, Danielsen SA, Kryeziu K, Elez E, Tabernero J, Guinney J, Palmer HG, Nesbakken A, Kallioniemi O, et al. Colorectal cancer Consensus Molecular Subtypes translated to preclinical models uncover potentially targetable cancer-cell dependencies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29242316 DOI: 10.1158/1078-0432.Ccr-17-1234  0.426
2017 Roumeliotis TI, Williams SP, Gonçalves E, Alsinet C, Del Castillo Velasco-Herrera M, Aben N, Ghavidel FZ, Michaut M, Schubert M, Price S, Wright JC, Yu L, Yang M, Dienstmann R, Guinney J, et al. Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells. Cell Reports. 20: 2201-2214. PMID 28854368 DOI: 10.1016/J.Celrep.2017.08.010  0.392
2017 Dienstmann R, Mason MJ, Sinicrope FA, Phipps AI, Tejpar S, Nesbakken A, Danielsen SA, Sveen A, Buchanan DD, Clendenning M, Rosty C, Bot B, Alberts SR, Milburn Jessup J, Lothe RA, ... ... Guinney J, et al. Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 28: 1023-1031. PMID 28453697 DOI: 10.1093/Annonc/Mdx052  0.364
2017 Gosline SJ, Weinberg H, Knight P, Yu T, Guo X, Prasad N, Jones A, Shrestha S, Boone B, Levy SE, La Rosa S, Guinney J, Bakker A. A high-throughput molecular data resource for cutaneous neurofibromas. Scientific Data. 4: 170045. PMID 28398289 DOI: 10.1038/Sdata.2017.45  0.31
2017 Dienstmann R, Vermeulen L, Guinney J, Kopetz S, Tejpar S, Tabernero J. Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer. Nature Reviews. Cancer. 17: 268. PMID 28332502 DOI: 10.1038/Nrc.2017.24  0.376
2017 Dienstmann R, Vermeulen L, Guinney J, Kopetz S, Tejpar S, Tabernero J. Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer. Nature Reviews. Cancer. PMID 28050011 DOI: 10.1038/Nrc.2016.126  0.441
2017 Davis JS, Yu R, Banerjee M, Jiang Z, Menter DG, Guinney J, Morris J, Broom BM, Maru D, Manyam GC, Chang S, Kopetz S. Distinct Patient and Tumor Characteristics of the Consensus Molecular Subtypes of Colorectal Cancer Gastroenterology. 152: S880. DOI: 10.1016/S0016-5085(17)33008-1  0.385
2016 Guinney J, Wang T, Laajala TD, Winner KK, Bare JC, Neto EC, Khan SA, Peddinti G, Airola A, Pahikkala T, Mirtti T, Yu T, Bot BM, Shen L, Abdallah K, et al. Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data. The Lancet. Oncology. PMID 27864015 DOI: 10.1016/S1470-2045(16)30560-5  0.381
2016 Barras D, Missiaglia E, Wirapati P, Sieber OM, Jorissen RN, Love C, Molloy PL, Jones IT, McLaughlin S, Gibbs P, Guinney J, Simon IM, Roth A, Bosman FT, Tejpar S, et al. BRAF V600E mutant colorectal cancer subtypes based on gene expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27354468 DOI: 10.1158/1078-0432.Ccr-16-0140  0.37
2016 Zhou FL, Guinney J, Wang T, Bare JC, Norman TC, Bot B, Shen L, Winner KK, Friend SH, Abdallah K, Stolovitzky GA, Xie Y, Costello J. Use of crowdsourced research to develop a prognostic model for first-line metastatic castrate resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 34: 180-180. DOI: 10.1200/Jco.2016.34.2_Suppl.180  0.369
2016 Dienstmann R, Tejpar S, Sinicrope FA, Phipps AI, Bot B, Friend SH, Delorenzi M, Newcomb PA, Sargent DJ, Jessup JM, Guinney J. Prognostication using molecular (mol) markers and clinicopathological (clpath) features in high-risk stage II/III colon cancer (CC). Journal of Clinical Oncology. 34: 3519-3519. DOI: 10.1200/Jco.2016.34.15_Suppl.3519  0.304
2016 Gosline SJ, Knight P, Yu T, Prasad N, Jones A, Shrestha S, Boone B, Levy SE, Link AJ, Galassie AC, Weinberg H, Friend S, Rosa SL, Guinney J, Bakker A. Abstract 772: The molecular landscape of dermal neurofibromatosis Cancer Research. 76: 772-772. DOI: 10.1158/1538-7445.Am2016-772  0.414
2015 Guinney J, Dienstmann R, Wang X, de Reyniès A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot BM, Morris JS, Simon IM, Gerster S, Fessler E, et al. The consensus molecular subtypes of colorectal cancer. Nature Medicine. PMID 26457759 DOI: 10.1038/Nm.3967  0.402
2015 Dienstmann R, Jang IS, Bot B, Friend S, Guinney J. Database of genomic biomarkers for cancer drugs and clinical targetability in solid tumors. Cancer Discovery. 5: 118-23. PMID 25656898 DOI: 10.1158/2159-8290.Cd-14-1118  0.445
2015 Jang IS, Dienstmann R, Margolin AA, Guinney J. Stepwise group sparse regression (SGSR): gene-set-based pharmacogenomic predictive models with stepwise selection of functional priors. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 32-43. PMID 25592566  0.36
2015 Commo F, Ferté C, Soria JC, Friend SH, André F, Guinney J. Impact of centralization on aCGH-based genomic profiles for precision medicine in oncology. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 582-8. PMID 25538175 DOI: 10.1093/Annonc/Mdu582  0.38
2015 Sinicrope FA, Shi Q, Smyrk TC, Thibodeau SN, Dienstmann R, Guinney J, Bot BM, Tejpar S, Delorenzi M, Goldberg RM, Mahoney M, Sargent DJ, Alberts SR. Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes. Gastroenterology. 148: 88-99. PMID 25305506 DOI: 10.1053/J.Gastro.2014.09.041  0.371
2015 Zhou FL, Guinney J, Abdallah K, Norman TC, Bot B, Costello J, Shen L, Wang T, Xie Y, Stolovitzky GA. Building a crowd-sourced challenge using clinical trial data. Journal of Clinical Oncology. 33: e16047-e16047. DOI: 10.1200/Jco.2015.33.15_Suppl.E16047  0.383
2015 Teufel M, Schwenke S, Seidel H, Beckmann G, Reischl J, Vonk R, Lenz H, Tabernero J, Siena S, Grothey A, Van Cutsem E, Jeffers M, Wilhelm S, Wagner A, Laurent D, ... ... Guinney J, et al. Molecular subtypes and outcomes in regorafenib-treated patients with metastatic colorectal cancer (mCRC) enrolled in the CORRECT trial. Journal of Clinical Oncology. 33: 3558-3558. DOI: 10.1200/Jco.2015.33.15_Suppl.3558  0.409
2015 Hu Y, Dienstmann R, Guinney J. Abstract B1-61: RNA-seq differential splicing analysis of over six hundred colorectal cancer transcriptomes reveals subtype-specific isoform usage Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B1-61  0.384
2015 Guinney J, Dienstmann R, Wang X, Reynies Ad, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot B, Morris JS, Simon I, Gerster S, Fessler E, et al. Abstract 603: Consensus molecular subtyping through a community of experts advances unsupervised gene expression-based disease classification and facilitates clinical translation Cancer Research. 75: 603-603. DOI: 10.1158/1538-7445.Am2015-603  0.453
2015 Hu Y, Dienstmann R, Guinney J. Abstract 1932: RNA-seq differential transcription analysis of TCGA colorectal cancer (CRC) transcriptomes reveals subtype-specific isoform usage Cancer Research. 75: 1932-1932. DOI: 10.1158/1538-7445.Am2015-1932  0.386
2015 Guinney J, Wang T, Bare C, Norman T, Bot B, Shen L, Winner K, Friend S, Abdallah K, Stolovitzky G, Xie Y, Zhou FL, Costello JC. Abstract B204: A DREAM Challenge to improve prognostic models in patients with metastatic castrate-resistant prostate cancer Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-B204  0.412
2014 Guinney J, Dienstmann R, Ferté C, Friend S, McCormick F. Social interactomes for enabling research communities. Cancer Discovery. 4: 1265-8. PMID 25367949 DOI: 10.1158/2159-8290.Cd-14-0774  0.302
2014 Kemp CJ, Moore JM, Moser R, Bernard B, Teater M, Smith LE, Rabaia NA, Gurley KE, Guinney J, Busch SE, Shaknovich R, Lobanenkov VV, Liggitt D, Shmulevich I, Melnick A, et al. CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer. Cell Reports. 7: 1020-9. PMID 24794443 DOI: 10.1016/J.Celrep.2014.04.004  0.375
2014 Guinney J, Ferté C, Dry J, McEwen R, Manceau G, Kao KJ, Chang KM, Bendtsen C, Hudson K, Huang E, Dougherty B, Ducreux M, Soria JC, Friend S, Derry J, et al. Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 265-72. PMID 24170544 DOI: 10.1158/1078-0432.Ccr-13-1943  0.345
2014 Dienstmann R, Guinney J, Delorenzi M, Reynies AD, Roepman P, Sadanandam A, Vermeulen L, Schlicker A, Missiaglia E, Soneson C, Marisa L, Homicsko K, Wang X, Simon I, Laurent-Puig P, et al. Colorectal Cancer Subtyping Consortium (CRCSC) identification of a consensus of molecular subtypes. Journal of Clinical Oncology. 32: 3511-3511. DOI: 10.1200/Jco.2014.32.15_Suppl.3511  0.386
2014 Ferte C, Chaibub Neto E, Commo F, Nikolova O, Jang iS, Gonen M, Lacroix L, Koubi-Pick V, Angevin E, Besse B, Ducreux M, Hollebecque A, Massard C, Margolin A, Friend SH, ... ... Guinney J, et al. Joint cell-line and patient modeling of drug sensitivity reveals novel molecular biomarkers for targeted and conventional chemotherapy. Journal of Clinical Oncology. 32: 2565-2565. DOI: 10.1200/Jco.2014.32.15_Suppl.2565  0.336
2014 Nikolova OH, Gönen M, Dienstmann R, Jang IS, Moser R, Cermelli S, Xu C, Mitchell RM, Mendez E, Grandori C, Kemp C, Friend S, Guinney J, Margolin A. Abstract 5323: Integrated computational cell-line modeling of drug sensitivity and high-throughput siRNA screening reveals novel molecular biomarkers for conventional chemotherapy Cancer Research. 74: 5323-5323. DOI: 10.1158/1538-7445.Am2014-5323  0.407
2014 Dienstmann R, Guinney J, Delorenzi M, De Reynies A, Roepman P, Sadanandam A, Vermeulen L, Schlicker A, Missiaglia E, Soneson C, Marisa L, Homicsko K, Wang X, Simon I, Laurent-Puig P, et al. Colorectal Cancer Subtyping Consortium (CRCSC) Identifies Consensus of Molecular Subtypes Annals of Oncology. 25: ii115. DOI: 10.1093/Annonc/Mdu193.25  0.387
2013 Ferté C, Trister AD, Huang E, Bot BM, Guinney J, Commo F, Sieberts S, André F, Besse B, Soria JC, Friend SH. Impact of bioinformatic procedures in the development and translation of high-throughput molecular classifiers in oncology. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4315-25. PMID 23780890 DOI: 10.1158/1078-0432.Ccr-12-3937  0.373
2013 Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, et al. Improving breast cancer survival analysis through competition-based multidimensional modeling. Plos Computational Biology. 9: e1003047. PMID 23671412 DOI: 10.1371/Journal.Pcbi.1003047  0.391
2013 Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, et al. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer. Science Translational Medicine. 5: 181re1. PMID 23596205 DOI: 10.1126/Scitranslmed.3006112  0.395
2013 Hänzelmann S, Castelo R, Guinney J. GSVA: gene set variation analysis for microarray and RNA-seq data. Bmc Bioinformatics. 14: 7. PMID 23323831 DOI: 10.1186/1471-2105-14-7  0.363
2013 Guinney J, Ferte C, Huang E, Derry J, Friend S. Abstract 2409: A model of RAS pathway in colorectal cancer elucidates molecular traits and drug sensitivity: an integrated analysis of gene expression from human tumors, mouse xenografts and the Cancer Cell Line Encyclopedia (CCLE). Cancer Research. 73: 2409-2409. DOI: 10.1158/1538-7445.Am2013-2409  0.411
2013 Ferte C, Guinney J, Derry J, huang eH, Besse B, Soria J. Abstract 1199: NSCLC KRAS G12C and G12V mutations drive different pathways and display specific drug sensitivity patterns. Cancer Research. 73: 1199-1199. DOI: 10.1158/1538-7445.Am2013-1199  0.385
2013 Ferté C, Neto EC, Sun C, Noecker C, Commo F, Nikolova O, Jang IS, Gonen M, Besse B, André F, Angevin E, Lacroix L, Mazoyer C, Hollebecque A, Massard C, ... ... Guinney J, et al. Abstract A130: Joint cell-line (CCLE, Sanger) and patient (TCGA) modeling of drug sensitivity reveals novel molecular biomarkers for targeted therapy and conventional chemotherapy. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A130  0.427
2012 Greenawalt DM, Sieberts SK, Cornelis MC, Girman CJ, Zhong H, Yang X, Guinney J, Qi L, Hu FB. Integrating genetic association, genetics of gene expression, and single nucleotide polymorphism set analysis to identify susceptibility Loci for type 2 diabetes mellitus. American Journal of Epidemiology. 176: 423-30. PMID 22865700 DOI: 10.1093/Aje/Kws123  0.306
2012 Huang CL, Lamb J, Chindelevitch L, Kostrowicki J, Guinney J, Delisi C, Ziemek D. Correlation set analysis: detecting active regulators in disease populations using prior causal knowledge. Bmc Bioinformatics. 13: 46. PMID 22443377 DOI: 10.1186/1471-2105-13-46  0.306
2011 Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, ... ... Guinney J, et al. Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting. Plos One. 6: e20090. PMID 21750698 DOI: 10.1371/Journal.Pone.0020090  0.354
2011 Onaitis M, D'Amico TA, Clark CP, Guinney J, Harpole DH, Rawlins EL. A 10-gene progenitor cell signature predicts poor prognosis in lung adenocarcinoma. The Annals of Thoracic Surgery. 91: 1046-50; discussion . PMID 21353202 DOI: 10.1016/J.Athoracsur.2010.12.054  0.31
2011 Zhang B, Derry J, Schadt E, Friend S, Zhu J, Dai X, Wang Z, Meng F, Tran L, Zhang Z, Guinney J, Clurman B, Wu G. Abstract PR8: From prediction to prognosis and therapeutics: The power of breast cancer transcriptional networks Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr8  0.403
2011 Guinney J, Wu Q, Mukherjee S. Estimating variable structure and dependence in multitask learning via gradients Machine Learning. 83: 265-287. DOI: 10.1007/S10994-010-5217-4  0.576
2009 Mendiratta P, Mostaghel E, Guinney J, Tewari AK, Porrello A, Barry WT, Nelson PS, Febbo PG. Genomic strategy for targeting therapy in castration-resistant prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2022-9. PMID 19289629 DOI: 10.1200/Jco.2008.17.2882  0.34
2008 Mendiratta P, Tewari A, Guinney J, Porrello A, Barry WT, Febbo PG. A genomic strategy for targeting therapy in castration-Independent Prostate Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 5067. PMID 27948753 DOI: 10.1200/Jco.2008.26.15_Suppl.5067  0.309
2008 Edelman EJ, Guinney J, Chi JT, Febbo PG, Mukherjee S. Modeling cancer progression via pathway dependencies. Plos Computational Biology. 4: e28. PMID 18282083 DOI: 10.1371/Journal.Pcbi.0040028  0.682
2006 Edelman E, Porrello A, Guinney J, Balakumaran B, Bild A, Febbo PG, Mukherjee S. Analysis of sample set enrichment scores: assaying the enrichment of sets of genes for individual samples in genome-wide expression profiles. Bioinformatics (Oxford, England). 22: e108-16. PMID 16873460 DOI: 10.1093/Bioinformatics/Btl231  0.673
Show low-probability matches.