Isabel R. Schlaepfer, Ph.D. - Publications

Affiliations: 
Integrative Physiology University of Colorado, Boulder, Boulder, CO, United States 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sawyer BT, Qamar L, Yamamoto TM, McMellen A, Watson ZL, Richer JK, Behbakht K, Schlaepfer IR, Bitler BG. Targeting fatty acid oxidation to promote anoikis and inhibit ovarian cancer progression. Molecular Cancer Research : McR. PMID 32198139 DOI: 10.1158/1541-7786.Mcr-19-1057  0.309
2020 Schlaepfer IR, Joshi M. CPT1A-mediated fat oxidation, mechanisms and therapeutic potential. Endocrinology. PMID 31900483 DOI: 10.1210/Endocr/Bqz046  0.306
2020 Hartman SJ, Nadales N, Bagby SM, Yacob BW, Gittleman BL, Estrada-Bernal A, Le AT, Lieu CH, Davis SL, Leal AD, Diamond JR, Messersmith WA, Schlaepfer IR, Pitts TM. Abstract 6387: Therapeutic targeting of lipid oxidation and apoptosis in pancreatic ductal adenocarcinoma Cancer Research. 80: 6387-6387. DOI: 10.1158/1538-7445.Am2020-6387  0.328
2019 Joshi M, Stoykova GE, Salzmann-Sullivan M, Dzieciatkowska M, Liebman LN, Deep G, Schlaepfer IR. CPT1A Supports Castration-Resistant Prostate Cancer in Androgen-Deprived Conditions. Cells. 8. PMID 31547059 DOI: 10.3390/Cells8101115  0.304
2019 Stoykova GE, Schlaepfer IR. Lipid Metabolism and Endocrine Resistance in Prostate Cancer, and New Opportunities for Therapy. International Journal of Molecular Sciences. 20. PMID 31142021 DOI: 10.3390/Ijms20112626  0.326
2018 Pathak GP, Shah R, Kennedy BE, Murphy JP, Clements D, Konda P, Giacomantonio M, Xu Z, Schlaepfer IR, Gujar S. RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 26: 2019-2033. PMID 30078441 DOI: 10.1016/J.Ymthe.2018.05.026  0.321
2018 Peak TC, Praharaj P, Panigrahi GK, Doyle M, Su Y, Schlaepfer IR, Singh R, Vander Griend DJ, Alickson J, Hemal A, Atala A, Deep G. Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells. Biochemical and Biophysical Research Communications. PMID 29627574 DOI: 10.1016/J.Bbrc.2018.04.038  0.328
2018 Guth AM, Salzmann-Sullivan M, Beaton C, Goldkorn A, Gibson EA, Kessler E, Lam E, Flaig T, Agarwal R, Schlaepfer IR. Abstract A021: CPT1A-mediated fat oxidation and its role in the immune response to prostate cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-A021  0.303
2017 Flaig TW, Salzmann-Sullivan M, Su LJ, Zhang Z, Joshi M, Gijón MA, Kim J, Arcaroli JJ, Van Bokhoven A, Lucia MS, La Rosa FG, Schlaepfer IR. Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade. Oncotarget. 8: 56051-56065. PMID 28915573 DOI: 10.18632/Oncotarget.17359  0.349
2016 Deep G, Schlaepfer IR. Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis. International Journal of Molecular Sciences. 17. PMID 27384557 DOI: 10.3390/Ijms17071061  0.346
2016 Schlaepfer IR, Deep G, Agarwal R, Zhang Z, Salzmann-Sullivan M, Su L, Flaig T. Abstract 1055: CPT1A-mediated lipid catabolism modulates growth, AR expression and hypoxia survival of prostate cancer Cancer Research. 76: 1055-1055. DOI: 10.1158/1538-7445.Am2016-1055  0.344
2015 Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G. Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation. Oncotarget. PMID 26087400 DOI: 10.18632/Oncotarget.4479  0.33
2015 Schlaepfer IR, Salzmann-Sullivan M, Su L, Glode LM, Flaig T. Abstract 1483: Lipid oxidation via CPT1 as a target for prostate cancer imaging and therapy Cancer Research. 75: 1483-1483. DOI: 10.1158/1538-7445.Am2015-1483  0.357
2014 Potcoava MC, Futia GL, Aughenbaugh J, Schlaepfer IR, Gibson EA. Raman and coherent anti-Stokes Raman scattering microscopy studies of changes in lipid content and composition in hormone-treated breast and prostate cancer cells. Journal of Biomedical Optics. 19: 111605. PMID 24933682 DOI: 10.1117/1.Jbo.19.11.111605  0.319
2014 Schlaepfer IR, Pac CT, Serkova NJ, Deep G, Agarwal R, Cramer SD, Eckel RH, Glode LM. Abstract 107: Lipid metabolism inhibitors enhance glycolysis and FDG-PET imaging of prostate cancer tumors Cancer Research. 74: 107-107. DOI: 10.1158/1538-7445.Am2014-107  0.315
2014 Potcoava MC, Futia GL, Aughenbaugh J, Schlaepfer I, Gibson EA. Micro-Raman spectroscopy studies of changes in lipid composition in breast and prostate cancer cells treated with MPA and R1881 hormones Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8939. DOI: 10.1117/12.2040696  0.311
2012 Schlaepfer IR, Hitz CA, Gijón MA, Bergman BC, Eckel RH, Jacobsen BM. Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel. Molecular and Cellular Endocrinology. 363: 111-21. PMID 22922095 DOI: 10.1016/J.Mce.2012.08.005  0.314
2012 Stephens SH, Hoft NR, Schlaepfer IR, Young SE, Corley RC, McQueen MB, Hopfer C, Crowley T, Stallings M, Hewitt J, Ehringer MA. Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. Behavior Genetics. 42: 402-14. PMID 22042234 DOI: 10.1007/S10519-011-9514-X  0.626
2009 Hoft NR, Corley RP, McQueen MB, Schlaepfer IR, Huizinga D, Ehringer MA. Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 698-706. PMID 18704094 DOI: 10.1038/Npp.2008.122  0.64
2008 Schlaepfer IR, Hoft NR, Ehringer MA. The genetic components of alcohol and nicotine co-addiction: from genes to behavior. Current Drug Abuse Reviews. 1: 124-34. PMID 19492010 DOI: 10.2174/1874473710801020124  0.629
2008 Schlaepfer IR, Hoft NR, Collins AC, Corley RP, Hewitt JK, Hopfer CJ, Lessem JM, McQueen MB, Rhee SH, Ehringer MA. The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults. Biological Psychiatry. 63: 1039-46. PMID 18163978 DOI: 10.1016/J.Biopsych.2007.10.024  0.642
2008 Zeiger JS, Haberstick BC, Schlaepfer I, Collins AC, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Lessem J, McQueen MB, Rhee SH, Ehringer MA. The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco. Human Molecular Genetics. 17: 724-34. PMID 18055561 DOI: 10.1093/Hmg/Ddm344  0.637
2007 Schlaepfer IR, Clegg HV, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Krauter K, Lessem J, Rhee SH, Stallings MC, Wehner JM, Young SE, Ehringer MA. The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition. Addiction Biology. 12: 200-9. PMID 17508994 DOI: 10.1111/J.1369-1600.2007.00063.X  0.613
2007 Ehringer MA, Clegg HV, Collins AC, Corley RP, Crowley T, Hewitt JK, Hopfer CJ, Krauter K, Lessem J, Rhee SH, Schlaepfer I, Smolen A, Stallings MC, Young SE, Zeiger JS. Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 596-604. PMID 17226798 DOI: 10.1002/Ajmg.B.30464  0.644
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