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Kunjumon Vadakkan, Ph.D, M.D - Publications

Affiliations: 
Neurosearch Center, Toronto 
Area:
Neuroscience
Website:
http://semblancehypothesis.org/
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15/43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Wang H, Xu H, Wu LJ, Kim SS, Chen T, Koga K, Descalzi G, Gong B, Vadakkan KI, Zhang X, Kaang BK, Zhuo M. Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain. Science Translational Medicine. 3: 65ra3. PMID 21228397 DOI: 10.1126/Scitranslmed.3001269  0.718
2009 Sowa NA, Vadakkan KI, Zylka MJ. Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception. Plos One. 4: e4248. PMID 19158948 DOI: 10.1371/Journal.Pone.0004248  0.699
2008 Xu H, Wu LJ, Wang H, Zhang X, Vadakkan KI, Kim SS, Steenland HW, Zhuo M. Presynaptic and postsynaptic amplifications of neuropathic pain in the anterior cingulate cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7445-53. PMID 18632948 DOI: 10.1523/Jneurosci.1812-08.2008  0.728
2008 Zhang F, Vadakkan KI, Kim SS, Wu LJ, Shang Y, Zhuo M. Selective activation of microglia in spinal cord but not higher cortical regions following nerve injury in adult mouse. Molecular Pain. 4: 15. PMID 18423014 DOI: 10.1186/1744-8069-4-15  0.681
2007 Wu LJ, Vadakkan KI, Zhuo M. ATP-induced chemotaxis of microglial processes requires P2Y receptor-activated initiation of outward potassium currents. Glia. 55: 810-21. PMID 17357150 DOI: 10.1002/glia.20500  0.593
2007 Wu LJ, Ko SW, Toyoda H, Zhao MG, Xu H, Vadakkan KI, Ren M, Knifed E, Shum F, Quan J, Zhang XH, Zhuo M. Increased anxiety-like behavior and enhanced synaptic efficacy in the amygdala of GluR5 knockout mice. Plos One. 2: e167. PMID 17245443 DOI: 10.1371/journal.pone.0000167  0.647
2007 Wang H, Gong B, Vadakkan KI, Toyoda H, Kaang BK, Zhuo M. Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 282: 1507-17. PMID 17121841 DOI: 10.1074/Jbc.M607291200  0.697
2007 Vadakkan KI, Xu H, Zhuo M. Common characteristics and pathways in neuropathic pain of different etiologies Drug Discovery Today: Disease Models. 3: 413-417. DOI: 10.1016/j.ddmod.2006.12.001  0.572
2006 Vadakkan KI, Li B, De Boni U. Trend towards varying combinatorial centromere association in morphologically identical clusters in Purkinje neurons. Cell & Chromosome. 5: 1. PMID 17156432 DOI: 10.1186/1475-9268-5-1  0.628
2006 Xu H, Wu LJ, Zhao MG, Toyoda H, Vadakkan KI, Jia Y, Pinaud R, Zhuo M. Presynaptic regulation of the inhibitory transmission by GluR5-containing kainate receptors in spinal substantia gelatinosa. Molecular Pain. 2: 29. PMID 16948848 DOI: 10.1186/1744-8069-2-29  0.689
2006 Vadakkan KI, Li B, De Boni U. Cell-type specific proximity of centromeric domains of one homologue each of chromosomes 2 and 11 in nuclei of cerebellar Purkinje neurons. Chromosoma. 115: 395-402. PMID 16741706 DOI: 10.1007/s00412-006-0069-1  0.624
2006 Vadakkan KI, Wang H, Ko SW, Zastepa E, Petrovic MJ, Sluka KA, Zhuo M. Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases. Molecular Pain. 2: 7. PMID 16503978 DOI: 10.1186/1744-8069-2-7  0.59
2006 Wei F, Vadakkan KI, Toyoda H, Wu LJ, Zhao MG, Xu H, Shum FW, Jia YH, Zhuo M. Calcium calmodulin-stimulated adenylyl cyclases contribute to activation of extracellular signal-regulated kinase in spinal dorsal horn neurons in adult rats and mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 851-61. PMID 16421305 DOI: 10.1523/JNEUROSCI.3292-05.2006  0.691
2005 Vadakkan KI, Jia YH, Zhuo M. A behavioral model of neuropathic pain induced by ligation of the common peroneal nerve in mice. The Journal of Pain : Official Journal of the American Pain Society. 6: 747-56. PMID 16275599 DOI: 10.1016/j.jpain.2005.07.005  0.552
2005 Ko SW, Vadakkan KI, Ao H, Gallitano-Mendel A, Wei F, Milbrandt J, Zhuo M. Selective contribution of Egr1 (zif/268) to persistent inflammatory pain. The Journal of Pain : Official Journal of the American Pain Society. 6: 12-20. PMID 15629414 DOI: 10.1016/J.Jpain.2004.10.001  0.56
Low-probability matches (unlikely to be authored by this person)
2015 Vadakkan KI. The functional role of all postsynaptic potentials examined from a first-person frame of reference. Reviews in the Neurosciences. PMID 26540219 DOI: 10.1515/revneuro-2015-0036  0.296
2013 Vadakkan KI. A supplementary circuit rule-set for the neuronal wiring. Frontiers in Human Neuroscience. 7: 170. PMID 23641209 DOI: 10.3389/fnhum.2013.00170  0.243
2010 Vadakkan KI. Framework of Consciousness from Semblance of Activity at Functionally LINKed Postsynaptic Membranes. Frontiers in Psychology. 1: 168. PMID 21833231 DOI: 10.3389/fpsyg.2010.00168  0.211
2012 Vadakkan KI. A structure-function mechanism for schizophrenia. Frontiers in Psychiatry. 3: 108. PMID 23293606 DOI: 10.3389/fpsyt.2012.00108  0.198
2014 Vadakkan KI. An Electronic Circuit Model of the Interpostsynaptic Functional LINK Designed to Study the Formation of Internal Sensations in the Nervous System Advances in Artificial Neural Systems. 2014: 1-15. DOI: 10.1155/2014/318390  0.17
2016 Vadakkan KI. Neurodegenerative disorders share common features of "loss of function" states of a proposed mechanism of nervous system functions. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 83: 412-430. PMID 27424323 DOI: 10.1016/j.biopha.2016.06.042  0.157
2016 Vadakkan KI. Rapid chain generation of interpostsynaptic functional LINKs can trigger seizure generation: Evidence for potential interconnections from pathology to behavior. Epilepsy & Behavior : E&B. 59: 28-41. PMID 27085478 DOI: 10.1016/j.yebeh.2016.03.014  0.147
2011 Vadakkan KI. Processing Semblances Induced through Inter-Postsynaptic Functional LINKs, Presumed Biological Parallels of K-Lines Proposed for Building Artificial Intelligence. Frontiers in Neuroengineering. 4: 8. PMID 21845180 DOI: 10.3389/fneng.2011.00008  0.14
2020 Vadakkan KI. A derived mechanism of nervous system functions explains aging-related neurodegeneration as a gradual loss of an evolutionary adaptation Current Aging Science. PMID 31870273 DOI: doi: 10.2174/1874609813666191223092451  0.132
2019 Vadakkan KI. A derived mechanism of the nervous system functions explains aging-related neurodegeneration as a gradual loss of an evolutionary adaptation. Current Aging Science. PMID 31870273 DOI: 10.2174/1874609813666191223092451  0.132
2015 Vadakkan KI. A pressure-reversible cellular mechanism of general anesthetics capable of altering a possible mechanism for consciousness. Springerplus. 4: 485. PMID 26380161 DOI: 10.1186/s40064-015-1283-1  0.127
2012 Vadakkan KI. The nature of "internal sensations" of higher brain functions may be derived from the design rules for artificial machines that can produce them. Journal of Biological Engineering. 6: 21. PMID 23126434 DOI: 10.1186/1754-1611-6-21  0.124
2011 Vadakkan KI. A possible mechanism of transfer of memories from the hippocampus to the cortex. Medical Hypotheses. 77: 234-43. PMID 21601989 DOI: 10.1016/j.mehy.2011.04.020  0.122
2012 Odero G, Snow W, Vadakkan K, Albensi BC. Roles for NF-κB in regulating gene expression in synaptic plasticity and memory Transcription Factors Creb and Nf-Kb: Involvement in Synaptic Plasticity and Memory Formation. 66-78. DOI: 10.2174/978160805257811201010066  0.119
2018 Vadakkan KI. A potential mechanism for first-person internal sensation of memory provides evidence for the relationship between learning and LTP induction Behavioural Brain Research. 360: 16-35. PMID 30502355 DOI: 10.1016/j.bbr.2018.11.038  0.105
2016 Vadakkan KI. Substantive nature of sleep in updating the temporal conditions necessary for inducing units of internal sensations. Sleep Science (SãO Paulo, Brazil). 9: 60-4. PMID 27656266 DOI: 10.1016/j.slsci.2016.05.001  0.097
2018 Vadakkan KI. Corrigendum to: The functional role of all postsynaptic potentials examined from a first-person frame of reference. Reviews in the Neurosciences. PMID 30243017 DOI: 10.1515/revneuro-2018-0077  0.093
2016 Vadakkan KI. Corrigendum to: The functional role of all postsynaptic potentials examined from a first-person frame of reference. Reviews in the Neurosciences. PMID 26959538 DOI: 10.1515/revneuro-2016-0005  0.093
2015 Vadakkan KI. A framework for the first-person internal sensation of visual perception in mammals and a comparable circuitry for olfactory perception in Drosophila. Springerplus. 4: 833. PMID 26753120 DOI: 10.1186/s40064-015-1568-4  0.08
2021 Vadakkan KI. Framework for internal sensation of pleasure using constraints from disparate findings in nucleus accumbens. World Journal of Psychiatry. 11: 681-695. PMID 34733636 DOI: 10.5498/wjp.v11.i10.681  0.07
2017 Vadakkan KI. The necessity for the observer to examine the system from a first-person frame of reference to trace the path of generation of inner sensations F1000research. 4: 173. DOI: 10.12688/F1000RESEARCH.6720.2  0.068
2021 Vadakkan KI. Neurological disorders of COVID-19 can be explained in terms of both "loss and gain of function" states of a solution for the nervous system. Brain Circulation. 7: 217-222. PMID 34667907 DOI: 10.4103/bc.bc_46_21  0.065
2019 Vadakkan KI. From cells to sensations: A window to the physics of mind. Physics of Life Reviews. PMID 31759872 DOI: 10.1016/j.plrev.2019.10.002  0.06
2019 Vadakkan KI. From cells to sensations: A window to the physics of mind Physics of Life Reviews. 31: 44-78. PMID 31759872 DOI: 10.1016/j.plrev.2019.10.002  0.06
2015 Vadakkan KI, Mammen T, Wadhwa VS. Sum of two catalytic activities of the glutamine synthetase enzyme is a blood biomarker for stroke and is optimized for a rapid diagnostic test. International Journal of Stroke : Official Journal of the International Stroke Society. 10: E1-2. PMID 25491548 DOI: 10.1111/ijs.12382  0.043
2015 Vadakkan KI. The necessity of studying higher brain functions from a first-person frame of reference F1000research. 4: 173. DOI: 10.12688/F1000RESEARCH.6720.1  0.029
2019 Vadakkan KI. From cells to sensations: A window to the physics of mind. Physics of Life Reviews. 31: 44-78. PMID 31759872 DOI: 10.1016/j.plrev.2019.10.002  0.026
2015 Vadakkan K. A structural unit of brain networks that can operate in unison with synaptic connections and can impart needed functions F1000research. 6. DOI: 10.7490/F1000Research.1098329.1  0.387
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