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Arianne L. Theiss, Ph.D. - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Alula KM, Dowdell AS, LeBere B, Lee JS, Levens CL, Kuhn KA, Kaipparettu BA, Thompson WE, Blumberg RS, Colgan SP, Theiss AL. Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice. Microbiome. 11: 256. PMID 37978573 DOI: 10.1186/s40168-023-01686-9  0.371
2020 Delgado-Deida Y, Alula KM, Theiss AL. The influence of mitochondrial-directed regulation of Wnt signaling on tumorigenesis. Gastroenterology Report. 8: 215-223. PMID 32665853 DOI: 10.1093/Gastro/Goaa025  0.331
2020 Jackson DN, Alula KM, Delgado-Deida Y, Tabti R, Turner K, Wang X, Venuprasad K, Souza RF, Désaubry L, Theiss AL. The synthetic small molecule FL3 combats intestinal tumorigenesis via Axin1-mediated inhibition of Wnt/beta-catenin signaling. Cancer Research. PMID 32665357 DOI: 10.1158/0008-5472.Can-20-0216  0.359
2020 Mukherjee S, Kumar R, Tsakem Lenou E, Basrur V, Kontoyiannis DL, Ioakeimidis F, Mosialos G, Theiss AL, Flavell RA, Venuprasad K. Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation. Nature Immunology. PMID 32424362 DOI: 10.1038/S41590-020-0681-X  0.36
2020 Kathania M, Tsakem EL, Theiss AL, Venuprasad K. Gut Microbiota Contributes to Spontaneous Colitis in E3 Ligase Itch-Deficient Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 32169841 DOI: 10.4049/Jimmunol.1701478  0.38
2020 Jackson DN, Panopoulos M, Neumann WL, Turner K, Cantarel BL, Thompson-Snipes L, Dassopoulos T, Feagins LA, Souza RF, Mills JC, Blumberg RS, Venuprasad K, Thompson WE, Theiss AL. Mitochondrial dysfunction during loss of prohibitin 1 triggers Paneth cell defects and ileitis. Gut. PMID 32111635 DOI: 10.1136/Gutjnl-2019-319523  0.405
2020 Alula KM, Delgado-Deida Y, Smith AD, Kim DS, Jackson DN, Dassopoulos T, Feagins LA, Theiss AL. Tu1290 PANETH CELL DEFECTS IN CROHN'S DISEASE PATIENTS ARE ASSOCIATED WITH MITOCHONDRIAL DAMAGE Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33298-4  0.363
2019 Jackson DN, Theiss AL. Gut bacteria signaling to mitochondria in intestinal inflammation and cancer. Gut Microbes. 1-20. PMID 30913966 DOI: 10.1080/19490976.2019.1592421  0.444
2018 Han J, Jackson D, Holm J, Turner K, Ashcraft P, Wang X, Cook B, Arning E, Genta RM, Venuprasad K, Souza RF, Sweetman L, Theiss AL. Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339485 DOI: 10.1073/Pnas.1712625115  0.329
2017 Paul J, Singh AK, Kathania M, Elviche TL, Zeng M, Basrur V, Theiss AL, Venuprasad K. IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5. Mucosal Immunology. PMID 28612841 DOI: 10.1038/Mi.2017.53  0.371
2017 Toden S, Theiss AL, Wang X, Goel A. Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis. Scientific Reports. 7: 814. PMID 28400554 DOI: 10.1038/S41598-017-00812-6  0.325
2017 Han J, Thompson WE, Souza RF, Theiss AL. Mitotempo Prevents Intestinal Epithelial Cell Mitochondrial Dysfunction and Paneth Cell Defects During Prohibitin Deletion Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30928-9  0.409
2016 Nadatani Y, Huo X, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Theiss A, Pham TH, Wang DH, Watanabe T, Fujiwara Y, Arakawa T, Spechler SJ, Souza RF. NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrett's Epithelial Cells. Cellular and Molecular Gastroenterology and Hepatology. 2: 439-453. PMID 27777967 DOI: 10.1016/J.Jcmgh.2016.03.006  0.341
2016 Gu P, Theiss A, Han J, Feagins LA. Increased Cell Adhesion Molecules, PECAM-1, ICAM-3, or VCAM-1, Predict Increased Risk for Flare in Patients With Quiescent Inflammatory Bowel Disease. Journal of Clinical Gastroenterology. PMID 27552332 DOI: 10.1097/Mcg.0000000000000618  0.364
2016 Panopoulos M, Han J, Souza RF, Thompson WE, Mills J, Theiss AL. 246 Paneth Cell-Specific Deletion of Prohibitin Triggers Ileitis in Mice Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30320-1  0.33
2015 Han J, Zhao Q, Basmadjian C, Désaubry L, Theiss AL. Flavaglines Ameliorate Experimental Colitis and Protect Against Intestinal Epithelial Cell Apoptosis and Mitochondrial Dysfunction. Inflammatory Bowel Diseases. PMID 26398710 DOI: 10.1097/Mib.0000000000000592  0.486
2015 Yu C, Huo X, Agoston AT, Zhang X, Theiss AL, Cheng E, Zhang Q, Zaika A, Pham TH, Wang DH, Lobie PE, Odze RD, Spechler SJ, Souza RF. Mitochondrial STAT3 Contributes to Transformation of Barrett's Epithelial Cells that Express Oncogenic Ras in a p53-Independent Fashion. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00462.2014. PMID 26045618 DOI: 10.1152/Ajpgi.00462.2014  0.368
2015 Panopoulos M, Han J, Theiss AL. Tu1848 Prohibitin Deficiency Leads to Defective Mitochondrial Clearance by Mitophagy in Intestinal Epithelial Cells Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)33118-8  0.403
2015 Han J, Panopoulos M, He B, O'Malley BW, Robine S, Genta RM, Souza RF, Thompson WE, Theiss AL. 111 Loss of Prohibitin in Intestinal Epithelial Cells Triggers the Development of Spontaneous Ileitis in Mice Subsequent to Mitochondrial Dysfunction and Paneth Cell Defects Gastroenterology. 148: S-29. DOI: 10.1016/S0016-5085(15)30100-1  0.334
2014 Han J, Theiss AL. Stat3: friend or foe in colitis and colitis-associated cancer? Inflammatory Bowel Diseases. 20: 2405-11. PMID 25185686 DOI: 10.1097/Mib.0000000000000180  0.433
2014 Han J, Yu C, Souza RF, Theiss AL. Prohibitin 1 modulates mitochondrial function of Stat3. Cellular Signalling. 26: 2086-95. PMID 24975845 DOI: 10.1016/J.Cellsig.2014.06.006  0.438
2014 Han J, Yu C, Souza RF, Theiss AL. 131 Prohibitin 1 Protects Against Mitochondrial Dysfunction in Intestinal Epithelial Cells via STAT3 Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)60126-8  0.425
2013 Kathiria AS, Butcher MA, Hansen JM, Theiss AL. Nrf2 is not required for epithelial prohibitin-dependent attenuation of experimental colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G885-96. PMID 23494124 DOI: 10.1152/Ajpgi.00327.2012  0.468
2013 Theiss AL, Neumann WL, Genta RM, He B, O'Malley BW, Robine S, Thompson WE, Souza RF, Boland CR. 226 Prohibitin Maintains Intestinal Epithelial Cell Homeostasis and Mitochondrial Function At Baseline and During Dextran Sodium Sulfate-Induced Colonic Injury Gastroenterology. 144: S-49. DOI: 10.1016/S0016-5085(13)60172-9  0.397
2012 Kathiria AS, Neumann WL, Rhees J, Hotchkiss E, Cheng Y, Genta RM, Meltzer SJ, Souza RF, Theiss AL. Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses. Cancer Research. 72: 5778-89. PMID 22869582 DOI: 10.1158/0008-5472.Can-12-0603  0.435
2012 Kathiria AS, Butcher LD, Feagins LA, Souza RF, Boland CR, Theiss AL. Prohibitin 1 modulates mitochondrial stress-related autophagy in human colonic epithelial cells. Plos One. 7: e31231. PMID 22363587 DOI: 10.1371/Journal.Pone.0031231  0.463
2012 Kathiria A, Butcher M, Neumann W, Genta R, Souza R, He B, OʼMalley B, Robine S, Thompson W, Theiss A. The Mitochondrial Protein Prohibitin Is Crucial for Maintaining Intestinal Epithelial Cell Homeostasis in Mice Inflammatory Bowel Diseases. 18: S99-S100. DOI: 10.1097/00054725-201212001-00251  0.428
2012 Kathiria AS, Butcher LD, Feagins LA, Souza RF, Boland CR, Theiss AL. 320 Prohibitin 1 Modulates Mitochondrial Stress-Related Autophagy in Human Colonic Epithelial Cells Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60281-9  0.362
2012 Kathiria AS, Neumann W, Genta RM, Souza RF, Theiss AL. 109 Prohibitin Attenuation of Colitis-Associated Tumorigenesis in Mice is Associated With Increased p53 Activation Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60104-8  0.306
2011 Theiss AL, Sitaraman SV. The role and therapeutic potential of prohibitin in disease. Biochimica Et Biophysica Acta. 1813: 1137-43. PMID 21296110 DOI: 10.1016/J.Bbamcr.2011.01.033  0.385
2011 Laroui H, Theiss AL, Yan Y, Dalmasso G, Nguyen HT, Sitaraman SV, Merlin D. Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon. Biomaterials. 32: 1218-28. PMID 20970849 DOI: 10.1016/J.Biomaterials.2010.09.062  0.316
2011 Theiss AL, Laroui H, Obertone TS, Chowdhury I, Thompson WE, Merlin D, Sitaraman SV. Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis. Inflammatory Bowel Diseases. 17: 1163-76. PMID 20872832 DOI: 10.1002/Ibd.21469  0.417
2009 Theiss AL, Jenkins AK, Okoro NI, Klapproth JM, Merlin D, Sitaraman SV. Prohibitin inhibits tumor necrosis factor alpha-induced nuclear factor-kappa B nuclear translocation via the novel mechanism of decreasing importin alpha3 expression. Molecular Biology of the Cell. 20: 4412-23. PMID 19710421 DOI: 10.1091/Mbc.E09-05-0361  0.388
2009 Theiss AL, Vijay-Kumar M, Obertone TS, Jones DP, Hansen JM, Gewirtz AT, Merlin D, Sitaraman SV. Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice. Gastroenterology. 137: 199-208, 208.e1-6. PMID 19327358 DOI: 10.1053/J.Gastro.2009.03.033  0.431
2009 Theiss AL, Jenkins AK, Merlin D, Sitaraman SV. S1715 Prohibitin Inhibits NF-kB Activation in Intestinal Epithelial Cells Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)61161-6  0.378
2009 Theiss AL, Vijay-Kumar M, Obertone TS, Jones D, Hansen J, Gewirtz AT, Merlin D, Sitaraman SV. 219 Prohibitin (PHB) Is a Novel Antioxidant That Attenuates Colonic Inflammation in Mice Gastroenterology. 136: A-41. DOI: 10.1016/S0016-5085(09)60190-6  0.367
2008 Theiss AL, Obertone TS, Merlin D, Sitaraman SV. S1288 Intestinal Epithelial Cell-Specific Overexpression of Prohibitin (PHB) Ameliorates Experimental Colitis in Mice Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)61010-0  0.408
2008 Theiss AL, Okoro NI, Merlin D, Sitaraman SV. 825 Reciprocal Effects of Tumor Necrosis Factor Alpha and Prohibitin in Intestinal Epithelial Cells Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60550-8  0.304
2007 Sasaki M, Sitaraman SV, Babbin BA, Gerner-Smidt P, Ribot EM, Garrett N, Alpern JA, Akyildiz A, Theiss AL, Nusrat A, Klapproth JM. Invasive Escherichia coli are a feature of Crohn's disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 1042-54. PMID 17660846 DOI: 10.1038/Labinvest.3700661  0.306
2007 Theiss AL, Obertone TS, Merlin D, Sitaraman SV. Interleukin-6 transcriptionally regulates prohibitin expression in intestinal epithelial cells. The Journal of Biological Chemistry. 282: 12804-12. PMID 17324931 DOI: 10.1074/Jbc.M609031200  0.37
2007 Theiss AL, Merlin D, Sitaraman SV. Keeping harmful intruders at bay: insights into the mechanism of barrier dysfunction during inflammatory bowel diseases. Gastroenterology. 132: 454-5; discussion 45. PMID 17241896 DOI: 10.1053/J.Gastro.2006.12.015  0.343
2007 Wang L, Srinivasan S, Theiss AL, Merlin D, Sitaraman SV. Interleukin-6 induces keratin expression in intestinal epithelial cells: potential role of keratin-8 in interleukin-6-induced barrier function alterations. The Journal of Biological Chemistry. 282: 8219-27. PMID 17213200 DOI: 10.1074/Jbc.M604068200  0.324
2007 Theiss AL, Idell RD, Srinivasan S, Klapproth JM, Jones DP, Merlin D, Sitaraman SV. Prohibitin protects against oxidative stress in intestinal epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 197-206. PMID 17135366 DOI: 10.1096/Fj.06-6801Com  0.406
2007 Theiss A, Idell R, Srinivasan S, Klapproth J, Jones D, Merlin D, Sitaraman S. P-0020: Prohibitin expression is decreased during Crohn's disease and combats against oxidative stress in intestinal epithelial cells Inflammatory Bowel Diseases. 13: 654-654. DOI: 10.1097/00054725-200705005-00040  0.384
2007 Theiss A, Idell R, Srinivasan S, Klapproth J, Jones D, Merlin D, Sitaraman S. Prohibitin expression is decreased during Crohnʼs disease and combats against oxidative stress in intestinal epithelial cells.: P-0020 Inflammatory Bowel Diseases. 13: 654. DOI: 10.1097/00054725-200705001-00040  0.378
2007 Klapproth JA, Sasaki M, Sitaraman SV, Alpern JA, Akyildiz A, Theiss AL, Nusrat A. Invasive E. coli from patients with inflammatory bowel disease regulate epithelial barrier function The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A585-B  0.349
2005 Theiss AL, Simmons JG, Jobin C, Lund PK. Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2. The Journal of Biological Chemistry. 280: 36099-109. PMID 16141211 DOI: 10.1074/Jbc.M505291200  0.392
2005 Theiss AL, Fuller CR, Simmons JG, Liu B, Sartor RB, Lund PK. Growth hormone reduces the severity of fibrosis associated with chronic intestinal inflammation. Gastroenterology. 129: 204-19. PMID 16012948 DOI: 10.1053/J.Gastro.2005.05.019  0.366
2004 Theiss AL, Fruchtman S, Lund PK. Growth factors in inflammatory bowel disease: the actions and interactions of growth hormone and insulin-like growth factor-I. Inflammatory Bowel Diseases. 10: 871-80. PMID 15626905 DOI: 10.1097/00054725-200411000-00021  0.342
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