Steffen Mueller, Ph.D. - Publications

Stony Brook University, Stony Brook, NY, United States 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mueller S, Stauft CB, Kalkeri R, Koidei F, Kushnir A, Tasker S, Coleman JR. A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates. Vaccine. PMID 32107060 DOI: 10.1016/j.vaccine.2020.02.056  0.56
2019 Le Nouën C, Luongo CL, Yang L, Mueller S, Wimmer E, DiNapoli JM, Collins PL, Buchholz UJ. Optimization of the codon-pair usage of human respiratory syncytial virus paradoxically resulted in reduced viral replication and reduced immunogenicity. Journal of Virology. PMID 31666376 DOI: 10.1128/JVI.01296-19  1
2019 Stauft CB, Yang C, Coleman JR, Boltz D, Chin C, Kushnir A, Mueller S. Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets. Plos One. 14: e0223784. PMID 31609986 DOI: 10.1371/journal.pone.0223784  0.56
2018 Stauft CB, Shen SH, Song Y, Gorbatsevych O, Asare E, Futcher B, Mueller S, Payne A, Brecher M, Kramer L, Wimmer E. Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes. Plos One. 13: e0198303. PMID 30192757 DOI: 10.1371/journal.pone.0198303  1
2018 Kaplan BS, Souza CK, Gauger PC, Stauft CB, Robert Coleman J, Mueller S, Vincent AL. Vaccination of pigs with a codon-pair bias de-optimized live attenuated influenza vaccine protects from homologous challenge. Vaccine. PMID 29366707 DOI: 10.1016/j.vaccine.2018.01.027  0.48
2017 Song Y, Gorbatsevych O, Liu Y, Mugavero J, Shen SH, Ward CB, Asare E, Jiang P, Paul AV, Mueller S, Wimmer E. Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973853 DOI: 10.1073/pnas.1714385114  1
2017 Le Nouën C, McCarty T, Brown M, Smith ML, Lleras R, Dolan MA, Mehedi M, Yang L, Luongo C, Liang B, Munir S, DiNapoli JM, Mueller S, Wimmer E, Collins PL, et al. Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049853 DOI: 10.1073/pnas.1619242114  1
2016 Kraus AK, Chen J, Edenhofer I, Ravens I, Gaspert A, Cippà PE, Mueller S, Wuthrich RP, Segerer S, Bernhardt G, Fehr T. The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation. Plos One. 11: e0147951. PMID 26840537 DOI: 10.1371/journal.pone.0147951  1
2015 Broadbent AJ, Santos CP, Anafu A, Wimmer E, Mueller S, Subbarao K. Evaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets. Vaccine. PMID 26655630 DOI: 10.1016/j.vaccine.2015.11.054  1
2015 Futcher B, Gorbatsevych O, Shen SH, Stauft CB, Song Y, Wang B, Leatherwood J, Gardin J, Yurovsky A, Mueller S, Wimmer E. Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished. Proceedings of the National Academy of Sciences of the United States of America. 112: E3635-6. PMID 26071446 DOI: 10.1073/pnas.1507710112  1
2015 Wang B, Yang C, Tekes G, Mueller S, Paul A, Whelan SP, Wimmer E. Recoding of the vesicular stomatitis virus L gene by computer-aided design provides a live, attenuated vaccine candidate. Mbio. 6. PMID 25827413 DOI: 10.1128/mBio.00237-15  1
2015 Shen SH, Stauft CB, Gorbatsevych O, Song Y, Ward CB, Yurovsky A, Mueller S, Futcher B, Wimmer E. Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference. Proceedings of the National Academy of Sciences of the United States of America. 112: 4749-54. PMID 25825721 DOI: 10.1073/pnas.1502864112  1
2014 Le Nouën C, Brock LG, Luongo C, McCarty T, Yang L, Mehedi M, Wimmer E, Mueller S, Collins PL, Buchholz UJ, DiNapoli JM. Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization. Proceedings of the National Academy of Sciences of the United States of America. 111: 13169-74. PMID 25157129 DOI: 10.1073/pnas.1411290111  1
2014 Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P. An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses. Plos Pathogens. 10: e1004052. PMID 24722315 DOI: 10.1371/journal.ppat.1004052  1
2013 Yang C, Skiena S, Futcher B, Mueller S, Wimmer E. Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 9481-6. PMID 23690603 DOI: 10.1073/pnas.1307473110  1
2013 Jahan N, Wimmer E, Mueller S. Polypyrimidine tract binding protein-1 (PTB1) is a determinant of the tissue and host tropism of a human rhinovirus/poliovirus chimera PV1(RIPO). Plos One. 8: e60791. PMID 23593313 DOI: 10.1371/journal.pone.0060791  1
2012 Song Y, Liu Y, Ward CB, Mueller S, Futcher B, Skiena S, Paul AV, Wimmer E. Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design. Proceedings of the National Academy of Sciences of the United States of America. 109: 14301-7. PMID 22886087 DOI: 10.1073/pnas.1211484109  1
2012 Cello J, Mueller S. Production of infectious poliovirus from synthetic viral genomes. Methods in Molecular Biology (Clifton, N.J.). 852: 181-93. PMID 22328434 DOI: 10.1007/978-1-61779-564-0_14  1
2011 Sitaraman V, Hearing P, Ward CB, Gnatenko DV, Wimmer E, Mueller S, Skiena S, Bahou WF. Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 108: 14294-9. PMID 21844368 DOI: 10.1073/pnas.1102883108  1
2011 Mueller S, Wimmer E. Introducing recombinant picornaviral genomes into cells. Cold Spring Harbor Protocols. 2011: 657-63. PMID 21632780 DOI: 10.1101/pdb.prot5626  1
2011 Jahan N, Wimmer E, Mueller S. A host-specific, temperature-sensitive translation defect determines the attenuation phenotype of a human rhinovirus/poliovirus chimera, PV1(RIPO). Journal of Virology. 85: 7225-35. PMID 21561914 DOI: 10.1128/JVI.01804-09  1
2011 Nimnual AS, Mueller S, Ward CB. Building new genomes - chemical synthesis of algorithmically designed attenuated viruses Biochemist. 33: 32-35.  1
2010 Liu Y, Wang C, Mueller S, Paul AV, Wimmer E, Jiang P. Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis. Plos Pathogens. 6: e1001066. PMID 20865167 DOI: 10.1371/journal.ppat.1001066  1
2010 Mueller S, Coleman JR, Papamichail D, Ward CB, Nimnual A, Futcher B, Skiena S, Wimmer E. Live attenuated influenza virus vaccines by computer-aided rational design. Nature Biotechnology. 28: 723-6. PMID 20543832 DOI: 10.1038/nbt.1636  1
2010 Wang Y, Zhang Z, Jain V, Yi J, Mueller S, Sokolov J, Liu Z, Levon K, Rigas B, Rafailovich MH. Potentiometric sensors based on surface molecular imprinting: Detection of cancer biomarkers and viruses Sensors and Actuators, B: Chemical. 146: 381-387. DOI: 10.1016/j.snb.2010.02.032  1
2009 Wimmer E, Mueller S, Tumpey TM, Taubenberger JK. Synthetic viruses: a new opportunity to understand and prevent viral disease. Nature Biotechnology. 27: 1163-72. PMID 20010599 DOI: 10.1038/nbt.1593  1
2009 Li X, Mueller S, Wimmer E. Inhibition of hepatitis C virus IRES-mediated translation by oligonucleotides. Virus Research. 146: 29-35. PMID 19720092 DOI: 10.1016/j.virusres.2009.08.008  1
2009 Satomi-Kobayashi S, Ueyama T, Mueller S, Toh R, Masano T, Sakoda T, Rikitake Y, Miyoshi J, Matsubara H, Oh H, Kawashima S, Hirata K, Takai Y. Deficiency of nectin-2 leads to cardiac fibrosis and dysfunction under chronic pressure overload. Hypertension. 54: 825-31. PMID 19667252 DOI: 10.1161/HYPERTENSIONAHA.109.130443  1
2009 Mueller S, Coleman JR, Wimmer E. Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis. Chemistry & Biology. 16: 337-47. PMID 19318214 DOI: 10.1016/j.chembiol.2009.03.002  1
2008 Zhang P, Mueller S, Morais MC, Bator CM, Bowman VD, Hafenstein S, Wimmer E, Rossmann MG. Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses. Proceedings of the National Academy of Sciences of the United States of America. 105: 18284-9. PMID 19011098 DOI: 10.1073/pnas.0807848105  1
2008 Coleman JR, Papamichail D, Skiena S, Futcher B, Wimmer E, Mueller S. Virus attenuation by genome-scale changes in codon pair bias. Science (New York, N.Y.). 320: 1784-7. PMID 18583614 DOI: 10.1126/science.1155761  1
2008 Richert L, Tuschl G, Viollon-Abadie C, Blanchard N, Bonet A, Heyd B, Halkic N, Wimmer E, Dolgos H, Mueller SO. Species differences in the response of liver drug-metabolizing enzymes to (S)-4-O-tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric acid (EMD 392949) in vivo and in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 702-14. PMID 18216275 DOI: 10.1124/dmd.107.018358  1
2007 Toyoda H, Yin J, Mueller S, Wimmer E, Cello J. Oncolytic treatment and cure of neuroblastoma by a novel attenuated poliovirus in a novel poliovirus-susceptible animal model. Cancer Research. 67: 2857-64. PMID 17363609 DOI: 10.1158/0008-5472.CAN-06-3713  1
2007 Wang B, Papamichail D, Mueller S, Skiena S. Two proteins for the price of one: The design of maximally compressed coding sequences Natural Computing. 6: 359-370. DOI: 10.1007/s11047-006-9031-7  1
2007 Mueller S, Coleman JR, Cello J, Paul A, Wimmer E, Papamichail D, Skiena S. Synthetic Biology: Synthesis and Modification of a Chemical Called Poliovirus Future Trends in Microelectronics: Up the Nano Creek. 113-121. DOI: 10.1002/9780470168264.ch11  1
2007 Wang Y, Zhang Z, Jain V, Yi J, Mueller S, Sokolov J, Levon K, Rigas B, Rafailovich M. High sensitivity detection of biomolecules using surface molecular imprinting technology 7th World Congress: Enabling Technologies and New Markets, Nanocomposites 2007 1
2006 Mueller S, Papamichail D, Coleman JR, Skiena S, Wimmer E. Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity. Journal of Virology. 80: 9687-96. PMID 16973573 DOI: 10.1128/JVI.00738-06  1
2006 Cohn CA, Mueller S, Wimmer E, Leifer N, Greenbaum S, Strongin DR, Schoonen MA. Pyrite-induced hydroxyl radical formation and its effect on nucleic acids. Geochemical Transactions. 7: 3. PMID 16759350 DOI: 10.1186/1467-4866-7-3  1
2005 Mueller SB, Micke O, Herbst H, Schaefer U, Willich N. Alpha-fetoprotein-positive carcinoma of the pancreas: A case report Anticancer Research. 25: 1671-1674. PMID 16033080  1
2005 Mueller S, Wimmer E, Cello J. Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event. Virus Research. 111: 175-93. PMID 15885840 DOI: 10.1016/j.virusres.2005.04.008  1
2003 Mueller S, Rosenquist TA, Takai Y, Bronson RA, Wimmer E. Loss of nectin-2 at Sertoli-spermatid junctions leads to male infertility and correlates with severe spermatozoan head and midpiece malformation, impaired binding to the zona pellucida, and oocyte penetration. Biology of Reproduction. 69: 1330-40. PMID 12801998 DOI: 10.1095/biolreprod.102.014670  1
2003 Mueller S, Wimmer E. Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomains. The Journal of Biological Chemistry. 278: 31251-60. PMID 12759359 DOI: 10.1074/jbc.M304166200  1
2003 He Y, Mueller S, Chipman PR, Bator CM, Peng X, Bowman VD, Mukhopadhyay S, Wimmer E, Kuhn RJ, Rossmann MG. Complexes of poliovirus serotypes with their common cellular receptor, CD155. Journal of Virology. 77: 4827-35. PMID 12663789 DOI: 10.1128/JVI.77.8.4827-4835.2003  1
2002 Thomas NA, Mueller S, Klein A, Jarrell KF. Mutants in flaI and flaJ of the archaeon Methanococcus voltae are deficient in flagellum assembly. Molecular Microbiology. 46: 879-87. PMID 12410843 DOI: 10.1046/j.1365-2958.2002.03220.x  1
2002 Iwasaki A, Welker R, Mueller S, Linehan M, Nomoto A, Wimmer E. Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection. The Journal of Infectious Diseases. 186: 585-92. PMID 12195344 DOI: 10.1086/342682  1
2002 Ozaki-Kuroda K, Nakanishi H, Ohta H, Tanaka H, Kurihara H, Mueller S, Irie K, Ikeda W, Sakai T, Wimmer E, Nishimune Y, Takai Y. Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions. Current Biology : Cb. 12: 1145-50. PMID 12121624 DOI: 10.1016/S0960-9822(02)00922-3  1
2002 Solecki DJ, Gromeier M, Mueller S, Bernhardt G, Wimmer E. Expression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog. The Journal of Biological Chemistry. 277: 25697-702. PMID 11983699 DOI: 10.1074/jbc.M201378200  1
2002 Mueller S, Cao X, Welker R, Wimmer E. Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis. The Journal of Biological Chemistry. 277: 7897-904. PMID 11751937 DOI: 10.1074/jbc.M111937200  1
2001 Li X, Lu HH, Mueller S, Wimmer E. The C-terminal residues of poliovirus proteinase 2A(pro) are critical for viral RNA replication but not for cis- or trans-proteolytic cleavage. The Journal of General Virology. 82: 397-408. PMID 11161279  1
2000 He Y, Bowman VD, Mueller S, Bator CM, Bella J, Peng X, Baker TS, Wimmer E, Kuhn RJ, Rossmann MG. Interaction of the poliovirus receptor with poliovirus. Proceedings of the National Academy of Sciences of the United States of America. 97: 79-84. PMID 10618374 DOI: 10.1073/pnas.97.1.79  1
1998 Mueller S, Wimmer E. Expression of foreign proteins by poliovirus polyprotein fusion: analysis of genetic stability reveals rapid deletions and formation of cardioviruslike open reading frames. Journal of Virology. 72: 20-31. PMID 9420196  1
1997 Gromeier M, Mueller S, Solecki D, Bossert B, Bernhardt G, Wimmer E. Determinants of poliovirus neurovirulence. Journal of Neurovirology. 3: S35-8. PMID 9179789  1
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