David B. Sykes, Ph.D. - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. PMID 27641501 DOI: 10.1016/j.cell.2016.08.057  1
2015 Lang D, Mead JS, Sykes DB. Hormones and the bone marrow: panhypopituitarism and pancytopenia in a man with a pituitary adenoma. Journal of General Internal Medicine. 30: 692-6. PMID 25583570 DOI: 10.1007/s11606-014-3161-x  1
2015 Rosado FG, Oliveira JL, Sohani AR, Schroyens W, Sykes DB, Kenderian SS, Lacy MQ, Kyle RA, Hoyer JD. Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 367-72. PMID 25216227 DOI: 10.1038/modpathol.2014.117  1
2015 Wu L, Walas S, Leung W, Sykes DB, Wu J, Lo EH, Lok J. Neuregulin1-β decreases IL-1β-induced neutrophil adhesion to human brain microvascular endothelial cells. Translational Stroke Research. 6: 116-24. PMID 24863743 DOI: 10.1007/s12975-014-0347-9  1
2013 Singh H, Lane AA, Correll M, Przychodzen B, Sykes DB, Stone RM, Ballen KK, Amrein PC, Maciejewski J, Attar EC. Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies. Blood Cancer Journal. 3: e117. PMID 23708642 DOI: 10.1038/bcj.2013.16  1
2013 Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, Vyas JM. Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes. The Journal of Biological Chemistry. 288: 16043-54. PMID 23609446 DOI: 10.1074/jbc.M113.473223  1
2013 Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin. Embo Molecular Medicine. 5: 430-40. PMID 23364955 DOI: 10.1002/emmm.201201606  1
2013 Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. Corrigendum to SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin [EMBO Mol Med] DOI:10.1002/emmm.201201606 Embo Molecular Medicine. 5: 482. DOI: 10.1002/emmm.201390004  1
2012 Schroyens W, O'Connell C, Sykes DB. Complete and partial responses of the TEMPI syndrome to bortezomib. The New England Journal of Medicine. 367: 778-80. PMID 22913703 DOI: 10.1056/NEJMc1205806  1
2012 Park D, Sykes DB, Scadden DT. The hematopoietic stem cell niche. Frontiers in Bioscience (Landmark Edition). 17: 30-9. PMID 22201730 DOI: 10.2741/3913  1
2011 Sykes DB, Schroyens W, O'Connell C. The TEMPI syndrome--a novel multisystem disease. The New England Journal of Medicine. 365: 475-7. PMID 21812700 DOI: 10.1056/NEJMc1106670  1
2010 Sykes DB, Attar EC, Bazari H. The authors reply New England Journal of Medicine. 363: 1875. DOI: 10.1056/NEJMc1007378  1
2009 Scheele JS, Kolanczyk M, Gantert M, Zemojtel T, Dorn A, Sykes DB, Sykes DP, Möbest DC, Kamps MP, Räpple D, Duchniewicz M. The Spt-Ada-Gcn5-acetyltransferase complex interaction motif of E2a is essential for a subset of transcriptional and oncogenic properties of E2a-Pbx1. Leukemia & Lymphoma. 50: 816-28. PMID 19399691 DOI: 10.1080/10428190902836107  1
2007 Odegaard JI, Vats D, Zhang L, Ricardo-Gonzalez R, Smith KL, Sykes DB, Kamps MP, Chawla A. Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages. Journal of Leukocyte Biology. 81: 711-9. PMID 17158607 DOI: 10.1189/jlb.0906590  1
2006 Wang GG, Calvo KR, Pasillas MP, Sykes DB, Häcker H, Kamps MP. Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8. Nature Methods. 3: 287-93. PMID 16554834 DOI: 10.1038/nmeth865  1
2004 Sykes DB, Kamps MP. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice. Molecular and Cellular Biology. 24: 1256-69. PMID 14729970 DOI: 10.1128/MCB.24.3.1256-1269.2004  1
2003 Sykes DB, Scheele J, Pasillas M, Kamps MP. Transcriptional profiling during the early differentiation of granulocyte and monocyte progenitors controlled by conditional versions of the E2a-Pbx1 oncoprotein. Leukemia & Lymphoma. 44: 1187-99. PMID 12916872 DOI: 10.1080/1042819031000090273  1
2003 Sykes DB, Kamps MP. Estrogen-regulated conditional oncoproteins: tools to address open questions in normal myeloid cell function, normal myeloid differentiation, and the genetic basis of differentiation arrest in myeloid leukemia. Leukemia & Lymphoma. 44: 1131-9. PMID 12916864 DOI: 10.1080/1042819031000063444  1
2002 Welch JS, Escoubet-Lozach L, Sykes DB, Liddiard K, Greaves DR, Glass CK. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. The Journal of Biological Chemistry. 277: 42821-9. PMID 12215441 DOI: 10.1074/jbc.M205873200  1
2002 Calvo KR, Sykes DB, Pasillas MP, Kamps MP. Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1. Oncogene. 21: 4247-56. PMID 12082612 DOI: 10.1038/sj.onc.1205516  1
2002 Klappacher GW, Lunyak VV, Sykes DB, Sawka-Verhelle D, Sage J, Brard G, Ngo SD, Gangadharan D, Jacks T, Kamps MP, Rose DW, Rosenfeld MG, Glass CK. An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. Cell. 109: 169-80. PMID 12007404 DOI: 10.1016/S0092-8674(02)00714-6  1
2001 Calvo KR, Knoepfler PS, Sykes DB, Pasillas MP, Kamps MP. Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 98: 13120-5. PMID 11687616 DOI: 10.1073/pnas.231115398  1
2001 Sykes DB, Kamps MP. Estrogen-dependent E2a/Pbx1 myeloid cell lines exhibit conditional differentiation that can be arrested by other leukemic oncoproteins. Blood. 98: 2308-18. PMID 11588024 DOI: 10.1182/blood.V98.8.2308  1
2001 Knoepfler PS, Sykes DB, Pasillas M, Kamps MP. HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation. Oncogene. 20: 5440-8. PMID 11571641 DOI: 10.1038/sj.onc.1204710  1
2001 Slupsky CM, Sykes DB, Gay GL, Sykes BD. The HoxB1 hexapeptide is a prefolded domain: implications for the Pbx1/Hox interaction. Protein Science : a Publication of the Protein Society. 10: 1244-53. PMID 11369863 DOI: 10.1110/ps.50901  1
2000 Calvo KR, Sykes DB, Pasillas M, Kamps MP. Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression. Molecular and Cellular Biology. 20: 3274-85. PMID 10757811 DOI: 10.1128/MCB.20.9.3274-3285.2000  1
1997 Parney IF, Petruk KC, Zhang C, Farr-Jones M, Sykes DB, Chang LJ. Granulocyte-macrophage colony-stimulating factor and B7-2 combination immunogene therapy in an allogeneic Hu-PBL-SCID/beige mouse-human glioblastoma multiforme model. Human Gene Therapy. 8: 1073-85. PMID 9189765 DOI: 10.1089/hum.1997.8.9-1073  1
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