David B. Horton, Ph.D. - Publications

Pharmaceutical Sciences University of Kentucky, Lexington, KY 
Drug and alcohol abuse

14/24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Nickell JR, Siripurapu KB, Horton DB, Zheng G, Crooks PA, Dwoskin LP. GZ-793A inhibits the neurochemical effects of methamphetamine via a selective interaction with the vesicular monoamine transporter-2. European Journal of Pharmacology. 795: 143-149. PMID 27986625 DOI: 10.1016/j.ejphar.2016.12.016  0.96
2015 Beckmann JS, Meyer AC, Pivavarchyk M, Horton DB, Zheng G, Smith AM, Wooters TE, McIntosh JM, Crooks PA, Bardo MT, Dwoskin LP. r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochemical Research. PMID 26227997 DOI: 10.1007/s11064-015-1680-4  0.96
2013 Horton DB, Nickell JR, Zheng G, Crooks PA, Dwoskin LP. GZ-793A, a lobelane analog, interacts with the vesicular monoamine transporter-2 to inhibit the effect of methamphetamine. Journal of Neurochemistry. 127: 177-86. PMID 23875622 DOI: 10.1111/jnc.12371  0.96
2013 Horton DB, Potter DM, Mead AN. A translational pharmacology approach to understanding the predictive value of abuse potential assessments. Behavioural Pharmacology. 24: 410-36. PMID 23873088 DOI: 10.1097/FBP.0b013e3283644d2e  0.96
2013 Narayanaswami V, Somkuwar SS, Horton DB, Cassis LA, Dwoskin LP. Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release. Biochemical Pharmacology. 86: 656-65. PMID 23831951 DOI: 10.1016/j.bcp.2013.06.025  0.96
2013 Zheng G, Horton DB, Penthala NR, Nickell JR, Culver JP, Deaciuc AG, Dwoskin LP, Crooks PA. Exploring the effect of N-substitution in nor-lobelane on the interaction with VMAT2: discovery of a potential clinical candidate for treatment of methamphetamine abuse. Medchemcomm. 4: 564-568. PMID 23527317 DOI: 10.1039/C3MD20374C  0.96
2011 Horton DB, Siripurapu KB, Zheng G, Crooks PA, Dwoskin LP. Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 339: 286-97. PMID 21778282 DOI: 10.1124/jpet.111.184770  0.96
2011 Meyer AC, Horton DB, Neugebauer NM, Wooters TE, Nickell JR, Dwoskin LP, Bardo MT. Tetrabenazine inhibition of monoamine uptake and methamphetamine behavioral effects: locomotor activity, drug discrimination and self-administration. Neuropharmacology. 61: 849-56. PMID 21669212 DOI: 10.1016/j.neuropharm.2011.05.033  0.96
2011 Horton DB, Siripurapu KB, Norrholm SD, Culver JP, Hojahmat M, Beckmann JS, Harrod SB, Deaciuc AG, Bardo MT, Crooks PA, Dwoskin LP. meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release. The Journal of Pharmacology and Experimental Therapeutics. 336: 940-51. PMID 21177475 DOI: 10.1124/jpet.110.175117  0.96
2011 Crooks PA, Zheng G, Vartak AP, Culver JP, Zheng F, Horton DB, Dwoskin LP. Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse. Current Topics in Medicinal Chemistry. 11: 1103-27. PMID 21050177 DOI: 10.2174/156802611795371332  0.96
2010 Beckmann JS, Siripurapu KB, Nickell JR, Horton DB, Denehy ED, Vartak A, Crooks PA, Dwoskin LP, Bardo MT. The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 335: 841-51. PMID 20805303 DOI: 10.1124/jpet.110.172742  0.96
2010 Hojahmat M, Horton DB, Norrholm SD, Miller DK, Grinevich VP, Deaciuc AG, Dwoskin LP, Crooks PA. Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters. Bioorganic & Medicinal Chemistry. 18: 640-9. PMID 20036131 DOI: 10.1016/j.bmc.2009.12.002  0.96
2007 Norrholm SD, Horton DB, Dwoskin LP. The promiscuity of the dopamine transporter: implications for the kinetic analysis of [3H]serotonin uptake in rat hippocampal and striatal synaptosomes. Neuropharmacology. 53: 982-9. PMID 18022203 DOI: 10.1016/j.neuropharm.2007.10.001  0.96
2006 Zheng G, Horton DB, Deaciuc AG, Dwoskin LP, Crooks PA. Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters. Bioorganic & Medicinal Chemistry Letters. 16: 5018-21. PMID 16905316 DOI: 10.1016/j.bmcl.2006.07.070  0.96
Low-probability matches
2015 Horton DB, Scott FI, Haynes K, Putt ME, Rose CD, Lewis JD, Strom BL. Antibiotic Exposure, Infection, and the Development of Pediatric Psoriasis: A Nested Case-Control Study. Jama Dermatology. 1-9. PMID 26560335 DOI: 10.1001/jamadermatol.2015.3650  0.01
2015 Horton DB, Scott FI, Haynes K, Putt ME, Rose CD, Lewis JD, Strom BL. Antibiotic Exposure and Juvenile Idiopathic Arthritis: A Case-Control Study. Pediatrics. 136: e333-43. PMID 26195533 DOI: 10.1542/peds.2015-0036  0.01
2012 Horton DB, Sherry DD, Baldassano RN, Weiss PF. Enthesitis is an Extraintestinal Manifestation of Pediatric Inflammatory Bowel Disease. Annals of Paediatric Rheumatology. 1. PMID 24349861 DOI: 10.5455/apr.102920121510  0.01
2007 Horton DB, DeCamp MM, Boiselle PM, Roberts DH. What caused an elevated diaphragm in this woman with cough and dyspnea? Journal of Respiratory Diseases. 28: 397-404.  0.01
2002 Schönbeck U, Gerdes N, Varo N, Reynolds RS, Horton DB, Bavendiek U, Robbie L, Ganz P, Kinlay S, Libby P. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. Circulation. 106: 2888-93. PMID 12460867 DOI: 10.1161/01.CIR.0000043029.52803.7B  0.01
2001 Horton DB, Libby P, Schonbeck U. Ligation of CD40 onvascular smooth muscle cells mediates loss of interstitial collagen via matrix metalloproteinase activity. Annals of the New York Academy of Sciences. 947: 329-36. PMID 11795284  0.01
2001 Herman MP, Sukhova GK, Libby P, Gerdes N, Tang N, Horton DB, Kilbride M, Breitbart RE, Chun M, Schönbeck U. Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling. Circulation. 104: 1899-904. PMID 11602491  0.01
1998 Lehman AL, Nakatsu Y, Ching A, Bronson RT, Oakey RJ, Keiper-Hrynko N, Finger JN, Durham-Pierre D, Horton DB, Newton JM, Lyon MF, Brilliant MH. A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 9436-41. PMID 9689098 DOI: 10.1073/pnas.95.16.9436  0.01
1968 Tenore KR, Horton DB, Duke TW. Effects of bottom substrate on the brackish water bivalve Rangia cuneata Chesapeake Science. 9: 238-248. DOI: 10.2307/1351314  0.01
1965 Berry RJ, Saila SB, Horton DB. Growth Studies of Winter Flounder, Pseudopleuronectes americanus (Walbaum), in Rhode Island Transactions of the American Fisheries Society. 94: 259-264. DOI: 10.1577/1548-8659(1965)94[259:GSOWFP]2.0.CO;2  0.01
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