| Year |
Citation |
Score |
| 2024 |
Scala SG, Kang MS, Cox SML, Rosa-Neto P, Massarweh G, Leyton M. Mesocorticolimbic function in cocaine polydrug users: A multimodal study of drug cue reactivity and cognitive regulation. Addiction Biology. 29: e13358. PMID 38221806 DOI: 10.1111/adb.13358 |
0.569 |
|
| 2022 |
Hansen JY, Shafiei G, Markello RD, Smart K, Cox SML, Nørgaard M, Beliveau V, Wu Y, Gallezot JD, Aumont É, Servaes S, Scala SG, DuBois JM, Wainstein G, Bezgin G, ... ... Leyton M, et al. Mapping neurotransmitter systems to the structural and functional organization of the human neocortex. Nature Neuroscience. PMID 36303070 DOI: 10.1038/s41593-022-01186-3 |
0.514 |
|
| 2021 |
Iqbal M, Cox SML, Jaworska N, Tippler M, Castellanos-Ryan N, Parent S, Dagher A, Vitaro F, Brendgen MR, Boivin M, Pihl RO, Côté SM, Tremblay RE, Séguin JR, Leyton M. A three-factor model of common early onset psychiatric disorders: temperament, adversity, and dopamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34625707 DOI: 10.1038/s41386-021-01187-z |
0.783 |
|
| 2021 |
D'Amour-Horvat V, Cox SML, Dagher A, Kolivakis T, Jaworska N, Leyton M. Cocaine cue-induced mesocorticolimbic activation in cocaine users: Effects of personality traits, lifetime drug use, and acute stimulant ingestion. Addiction Biology. e13094. PMID 34463411 DOI: 10.1111/adb.13094 |
0.781 |
|
| 2021 |
Cox SML, Castellanos-Ryan N, Parent S, Benkelfat C, Vitaro F, Pihl RO, Boivin M, Tremblay RE, Leyton M, Séguin JR. Externalizing Risk Pathways for Adolescent Substance Use and Its Developmental Onset: A Canadian Birth Cohort Study: Trajectoires de comportements extériorisés et le risque pour l'initiation et l'usage de substances des adolescents : Une étude de cohorte de naissance canadienne. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 706743720982429. PMID 33530707 DOI: 10.1177/0706743720982429 |
0.665 |
|
| 2020 |
Smart K, Nagano-Saito A, Milella MS, Sakae DY, Favier M, Vigneault E, Louie L, Hamilton A, Ferguson SSG, Rosa-Neto P, Narayanan S, El Mestikawy S, Leyton M, Benkelfat C. Metabotropic glutamate type 5 receptor binding availability during dextroamphetamine sensitization in mice and humans. Journal of Psychiatry & Neuroscience : Jpn. 45: 190162. PMID 32559027 DOI: 10.1503/Jpn.190162 |
0.68 |
|
| 2020 |
Cox SML, Tippler M, Jaworska N, Smart K, Castellanos-Ryan N, Durand F, Allard D, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté S, Tremblay RE, ... ... Leyton M, et al. mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32413893 DOI: 10.1038/S41386-020-0708-X |
0.782 |
|
| 2020 |
Lissemore JI, Nagano-Saito A, Smart K, Gravel P, Leyton M, Benkelfat C. Dopaminergic Plasticity in the Bilateral Hippocampus Following Threat Reversal in Humans. Scientific Reports. 10: 7627. PMID 32376865 DOI: 10.1038/s41598-020-63977-7 |
0.692 |
|
| 2020 |
Jaworska N, Cox SML, Tippler M, Castellanos-Ryan N, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté SM, Tremblay RE, Séguin JR, Leyton M. Extra-striatal D receptor availability in youth at risk for addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32259831 DOI: 10.1038/S41386-020-0662-7 |
0.803 |
|
| 2019 |
Vosberg DE, Leyton M, Flores C. The Netrin-1/DCC guidance system: dopamine pathway maturation and psychiatric disorders emerging in adolescence. Molecular Psychiatry. PMID 31659271 DOI: 10.1038/s41380-019-0561-7 |
0.788 |
|
| 2019 |
Bdair H, Tsai IH, Smart K, Benkelfat C, Leyton M, Kostikov A. Radiosynthesis of the diastereomerically pure (E)-[ C]ABP688. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 31418468 DOI: 10.1002/jlcr.3802 |
0.607 |
|
| 2019 |
Vosberg DE, Beaulé V, Torres-Berrío A, Cooke D, Chalupa A, Jaworska N, Cox SM, Larcher K, Zhang Y, Allard D, Durand F, Dagher A, Benkelfat C, Srour M, Tampieri D, ... ... Leyton M, et al. Neural Function in DCC Mutation Carriers with and without Mirror Movements. Annals of Neurology. PMID 30666715 DOI: 10.1002/Ana.25418 |
0.748 |
|
| 2019 |
Smart K, Cox SML, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M. Sex differences in [C]ABP688 binding: a positron emission tomography study of mGlu5 receptors. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30627817 DOI: 10.1007/S00259-018-4252-4 |
0.762 |
|
| 2019 |
Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M. Effect of (Z)-isomer content on [C]ABP688 binding potential in humans. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30607444 DOI: 10.1007/S00259-018-4237-3 |
0.76 |
|
| 2019 |
Chiarella J, Sild M, Casey KF, Massarweh G, Soucy J, Leyton M, Azar N, Tremblay RE, Hooker J, Benkelfat C, Booij L. The association between childhood stressors and histone deacetylase density in the brain of adults followed since childhood: A positron emission tomography study Psychoneuroendocrinology. 107: 6. DOI: 10.1016/J.Psyneuen.2019.07.013 |
0.565 |
|
| 2018 |
Shafiei G, Zeighami Y, Clark CA, Coull JT, Nagano-Saito A, Leyton M, Dagher A, Mišic B. Dopamine Signaling Modulates the Stability and Integration of Intrinsic Brain Networks. Cerebral Cortex (New York, N.Y. : 1991). PMID 30357316 DOI: 10.1093/Cercor/Bhy264 |
0.358 |
|
| 2018 |
Sharkey RJ, Bourque J, Larcher K, Misic B, Zhang Y, Altinkaya A, Sadikot A, Conrod P, Evans AC, Garavan H, Leyton M, Séguin JR, Pihl R, Dagher A. Mesolimbic connectivity signatures of impulsivity and BMI in early adolescence. Appetite. PMID 30273626 DOI: 10.1016/J.Appet.2018.09.019 |
0.541 |
|
| 2018 |
Smart K, Cox SML, Nagano-Saito A, Rosa-Neto P, Leyton M, Benkelfat C. Test-retest variability of [ C]ABP688 estimates of metabotropic glutamate receptor subtype 5 availability in humans. Synapse (New York, N.Y.). PMID 29935121 DOI: 10.1002/syn.22041 |
0.631 |
|
| 2018 |
Vosberg DE, Zhang Y, Menegaux A, Chalupa A, Manitt C, Zehntner S, Eng C, DeDuck K, Allard D, Durand F, Dagher A, Benkelfat C, Srour M, Joober R, Lepore F, ... ... Leyton M, et al. Mesocorticolimbic Connectivity and Volumetric Alterations in Mutation Carriers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29712788 DOI: 10.1523/Jneurosci.3251-17.2018 |
0.782 |
|
| 2018 |
Lissemore JI, Sookman D, Gravel P, Berney A, Barsoum A, Diksic M, Nordahl TE, Pinard G, Sibon I, Cottraux J, Leyton M, Benkelfat C. Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline. Translational Psychiatry. 8: 82. PMID 29666372 DOI: 10.1038/s41398-018-0128-4 |
0.624 |
|
| 2017 |
Shakra MA, Leyton M, Moghnieh H, Pruessner J, Dagher A, Pihl R. Neurobiological Correlates and Predictors of Two Distinct Personality Trait Pathways to Escalated Alcohol Use. Ebiomedicine. PMID 29292030 DOI: 10.1016/J.Ebiom.2017.11.025 |
0.509 |
|
| 2017 |
Cherkasova MV, Faridi N, Casey KF, Larcher K, O'Driscoll GA, Hechtman L, Joober R, Baker GB, Palmer J, Evans AC, Dagher A, Benkelfat C, Leyton M. Differential Associations between Cortical Thickness and Striatal Dopamine in Treatment-Naïve Adults with ADHD vs. Healthy Controls. Frontiers in Human Neuroscience. 11: 421. PMID 28878639 DOI: 10.3389/Fnhum.2017.00421 |
0.799 |
|
| 2017 |
Nagano-Saito A, Lissemore JI, Gravel P, Leyton M, Carbonell F, Benkelfat C. Posterior Dopamine D2/3 Receptors and Brain Network Functional Connectivity. Synapse (New York, N.Y.). PMID 28700819 DOI: 10.1002/syn.21993 |
0.607 |
|
| 2017 |
Cawley E, Tippler M, Coupland NJ, Benkelfat C, Boivin DB, Aan Het Rot M, Leyton M. Dopamine and light: effects on facial emotion recognition. Journal of Psychopharmacology (Oxford, England). 269881117711707. PMID 28633582 DOI: 10.1177/0269881117711707 |
0.773 |
|
| 2017 |
Cox SML, Yau Y, Larcher K, Durand F, Kolivakis T, Delaney JS, Dagher A, Benkelfat C, Leyton M. Cocaine Cue-Induced Dopamine Release in Recreational Cocaine Users. Scientific Reports. 7: 46665. PMID 28443614 DOI: 10.1038/srep46665 |
0.701 |
|
| 2017 |
Jaworska N, Cox SM, Casey KF, Boileau I, Cherkasova M, Larcher K, Dagher A, Benkelfat C, Leyton M. Is there a relation between novelty seeking, striatal dopamine release and frontal cortical thickness? Plos One. 12: e0174219. PMID 28346539 DOI: 10.1371/Journal.Pone.0174219 |
0.802 |
|
| 2017 |
Laroque F, Bourque J, Spinney S, Sharkey R, Baker T, Dagher A, Garavan H, Leyton M, Seguin J, Pihl R, Conrod P. 1.28 Early Cannabis Use Initiation at 12–14 Years Old Associated With Thinner Frontal and Temporal Cortical Thickness Journal of the American Academy of Child & Adolescent Psychiatry. 56: S161. DOI: 10.1016/J.Jaac.2017.09.042 |
0.486 |
|
| 2016 |
Bourque J, Baker TE, Dagher A, Evans AC, Garavan H, Leyton M, Séguin JR, Pihl R, Conrod PJ. Effects of delaying binge drinking on adolescent brain development: a longitudinal neuroimaging study. Bmc Psychiatry. 16: 445. PMID 27955636 DOI: 10.1186/S12888-016-1148-3 |
0.519 |
|
| 2016 |
Booij L, Welfeld K, Leyton M, Dagher A, Boileau I, Sibon I, Baker GB, Diksic M, Soucy JP, Pruessner JC, Cawley-Fiset E, Casey KF, Benkelfat C. Dopamine cross-sensitization between psychostimulant drugs and stress in healthy male volunteers. Translational Psychiatry. 6: e740. PMID 26905412 DOI: 10.1038/tp.2016.6 |
0.784 |
|
| 2016 |
Milella MS, Fotros A, Gravel P, Casey KF, Larcher K, Verhaeghe JA, Cox SM, Reader AJ, Dagher A, Benkelfat C, Leyton M. Cocaine cue-induced dopamine release in the human prefrontal cortex. Journal of Psychiatry & Neuroscience : Jpn. 41: 150207. PMID 26900792 DOI: 10.1503/Jpn.150207 |
0.807 |
|
| 2016 |
O'Hara CB, Keyes A, Renwick B, Leyton M, Campbell IC, Schmidt U. The Effects of Acute Dopamine Precursor Depletion on the Reinforcing Value of Exercise in Anorexia Nervosa. Plos One. 11: e0145894. PMID 26808920 DOI: 10.1371/journal.pone.0145894 |
0.347 |
|
| 2015 |
Larson MJ, Clayson PE, Primosch M, Leyton M, Steffensen SC. The Effects of Acute Dopamine Precursor Depletion on the Cognitive Control Functions of Performance Monitoring and Conflict Processing: An Event-Related Potential (ERP) Study. Plos One. 10: e0140770. PMID 26492082 DOI: 10.1371/Journal.Pone.0140770 |
0.356 |
|
| 2015 |
Cox SM, Frank MJ, Larcher K, Fellows LK, Clark CA, Leyton M, Dagher A. Striatal D1 and D2 signaling differentially predict learning from positive and negative outcomes. Neuroimage. 109: 95-101. PMID 25562824 DOI: 10.1016/j.neuroimage.2014.12.070 |
0.58 |
|
| 2014 |
D'Amour-Horvat V, Leyton M. Impulsive actions and choices in laboratory animals and humans: effects of high vs. low dopamine states produced by systemic treatments given to neurologically intact subjects. Frontiers in Behavioral Neuroscience. 8: 432. PMID 25566001 DOI: 10.3389/fnbeh.2014.00432 |
0.797 |
|
| 2014 |
Leyton M. What's deficient in reward deficiency? Journal of Psychiatry & Neuroscience : Jpn. 39: 291-3. PMID 25162147 DOI: 10.1503/jpn.140204 |
0.335 |
|
| 2014 |
Booij L, Soucy JP, Young SN, Regoli M, Gravel P, Diksic M, Leyton M, Pihl RO, Benkelfat C. Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study. Journal of Neurochemistry. 131: 634-44. PMID 25041501 DOI: 10.1111/Jnc.12826 |
0.746 |
|
| 2014 |
Milella MS, Marengo L, Larcher K, Fotros A, Dagher A, Rosa-Neto P, Benkelfat C, Leyton M. Limbic system mGluR5 availability in cocaine dependent subjects: a high-resolution PET [(11)C]ABP688 study. Neuroimage. 98: 195-202. PMID 24795154 DOI: 10.1016/J.Neuroimage.2014.04.061 |
0.804 |
|
| 2014 |
Leyton M, Vezina P. Dopamine ups and downs in vulnerability to addictions: a neurodevelopmental model. Trends in Pharmacological Sciences. 35: 268-76. PMID 24794705 DOI: 10.1016/j.tips.2014.04.002 |
0.658 |
|
| 2014 |
Carbonell F, Nagano-Saito A, Leyton M, Cisek P, Benkelfat C, He Y, Dagher A. Dopamine precursor depletion impairs structure and efficiency of resting state brain functional networks. Neuropharmacology. 84: 90-100. PMID 24412649 DOI: 10.1016/j.neuropharm.2013.12.021 |
0.639 |
|
| 2014 |
Cherkasova MV, Faridi N, Casey KF, O'Driscoll GA, Hechtman L, Joober R, Baker GB, Palmer J, Dagher A, Leyton M, Benkelfat C. Amphetamine-induced dopamine release and neurocognitive function in treatment-naive adults with ADHD. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1498-507. PMID 24378745 DOI: 10.1038/Npp.2013.349 |
0.803 |
|
| 2014 |
Young SN, Regoli M, Leyton M, Pihl RO, Benkelfat C. The effect of acute tryptophan depletion on mood and impulsivity in polydrug ecstasy users. Psychopharmacology. 231: 707-16. PMID 24142202 DOI: 10.1007/S00213-013-3287-2 |
0.736 |
|
| 2014 |
Casey KF, Benkelfat C, Cherkasova MV, Baker GB, Dagher A, Leyton M. Reduced dopamine response to amphetamine in subjects at ultra-high risk for addiction. Biological Psychiatry. 76: 23-30. PMID 24138922 DOI: 10.1016/J.Biopsych.2013.08.033 |
0.765 |
|
| 2014 |
Setiawan E, Pihl RO, Dagher A, Schlagintweit H, Casey KF, Benkelfat C, Leyton M. Differential striatal dopamine responses following oral alcohol in individuals at varying risk for dependence. Alcoholism, Clinical and Experimental Research. 38: 126-34. PMID 23919483 DOI: 10.1111/Acer.12218 |
0.785 |
|
| 2013 |
Becker S, Ceko M, Louis-Foster M, Elfassy NM, Leyton M, Shir Y, Schweinhardt P. Dopamine and pain sensitivity: neither sulpiride nor acute phenylalanine and tyrosine depletion have effects on thermal pain sensations in healthy volunteers. Plos One. 8: e80766. PMID 24236199 DOI: 10.1371/Journal.Pone.0080766 |
0.369 |
|
| 2013 |
Casey KF, Cherkasova MV, Larcher K, Evans AC, Baker GB, Dagher A, Benkelfat C, Leyton M. Individual differences in frontal cortical thickness correlate with the d-amphetamine-induced striatal dopamine response in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15285-94. PMID 24048857 DOI: 10.1523/Jneurosci.5029-12.2013 |
0.775 |
|
| 2013 |
Bohbot VD, Del Balso D, Conrad K, Konishi K, Leyton M. Caudate nucleus-dependent navigational strategies are associated with increased use of addictive drugs. Hippocampus. 23: 973-84. PMID 23939925 DOI: 10.1002/hipo.22187 |
0.327 |
|
| 2013 |
Nagano-Saito A, Dagher A, Booij L, Gravel P, Welfeld K, Casey KF, Leyton M, Benkelfat C. Stress-induced dopamine release in human medial prefrontal cortex--18F-fallypride/PET study in healthy volunteers. Synapse (New York, N.Y.). 67: 821-30. PMID 23939822 DOI: 10.1002/Syn.21700 |
0.763 |
|
| 2013 |
Cawley EI, Park S, aan het Rot M, Sancton K, Benkelfat C, Young SN, Boivin DB, Leyton M. Dopamine and light: dissecting effects on mood and motivational states in women with subsyndromal seasonal affective disorder. Journal of Psychiatry & Neuroscience : Jpn. 38: 388-97. PMID 23735584 DOI: 10.1503/Jpn.120181 |
0.792 |
|
| 2013 |
Fotros A, Casey KF, Larcher K, Verhaeghe JA, Cox SM, Gravel P, Reader AJ, Dagher A, Benkelfat C, Leyton M. Cocaine cue-induced dopamine release in amygdala and hippocampus: a high-resolution PET [¹â¸F]fallypride study in cocaine dependent participants. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1780-8. PMID 23546387 DOI: 10.1038/Npp.2013.77 |
0.81 |
|
| 2013 |
Leyton M, Vezina P. Striatal ups and downs: their roles in vulnerability to addictions in humans. Neuroscience and Biobehavioral Reviews. 37: 1999-2014. PMID 23333263 DOI: 10.1016/j.neubiorev.2013.01.018 |
0.644 |
|
| 2013 |
Fotros A, Casey KF, Larcher K, Verhaeghe JAJ, Cox SML, Gravel P, Reader AJ, Dagher A, Benkelfat C, Leyton M. Cue-Induced Dopamine Release in Striatal and Extra-striatal Regions in Cocaine Dependent Users: A High Resolution PET [18F]Fallypride Study Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 183. DOI: 10.1016/B978-0-12-800044-1.00166-5 |
0.809 |
|
| 2013 |
Casey KF, Benkelfat C, Cherkasova MV, Dagher A, Leyton M. Attenuated Amphetamine-Induced Dopamine Release in Subjects at Ultra-High Risk for Substance Dependence Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 57. DOI: 10.1016/B978-0-12-800044-1.00051-9 |
0.61 |
|
| 2012 |
Coull JT, Hwang HJ, Leyton M, Dagher A. Dopamine precursor depletion impairs timing in healthy volunteers by attenuating activity in putamen and supplementary motor area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16704-15. PMID 23175824 DOI: 10.1523/JNEUROSCI.1258-12.2012 |
0.361 |
|
| 2012 |
Setiawan E, Pihl RO, Benkelfat C, Leyton M. Influence of the OPRM1 A118G polymorphism on alcohol-induced euphoria, risk for alcoholism and the clinical efficacy of naltrexone. Pharmacogenomics. 13: 1161-72. PMID 22909206 DOI: 10.2217/Pgs.12.99 |
0.774 |
|
| 2012 |
Leyton M, Vezina P. On cue: striatal ups and downs in addictions. Biological Psychiatry. 72: e21-2. PMID 22789688 DOI: 10.1016/j.biopsych.2012.04.036 |
0.633 |
|
| 2012 |
Nagano-Saito A, Cisek P, Perna AS, Shirdel FZ, Benkelfat C, Leyton M, Dagher A. From anticipation to action, the role of dopamine in perceptual decision making: an fMRI-tyrosine depletion study. Journal of Neurophysiology. 108: 501-12. PMID 22552189 DOI: 10.1152/jn.00592.2011 |
0.632 |
|
| 2012 |
Booij L, Benkelfat C, Leyton M, Vitaro F, Gravel P, Lévesque ML, Arseneault L, Diksic M, Tremblay RE. Perinatal effects on in vivo measures of human brain serotonin synthesis in adulthood: a 27-year longitudinal study. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 22: 419-23. PMID 22257439 DOI: 10.1016/J.Euroneuro.2011.11.002 |
0.654 |
|
| 2012 |
Liggins J, Pihl RO, Benkelfat C, Leyton M. The dopamine augmenter L-DOPA does not affect positive mood in healthy human volunteers. Plos One. 7: e28370. PMID 22238577 DOI: 10.1371/Journal.Pone.0028370 |
0.82 |
|
| 2012 |
Labonte B, McLaughlin RJ, Dominguez-Lopez S, Bambico FR, Lucchino I, Ochoa-Sanchez R, Leyton M, Gobbi G. Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1319-30. PMID 22053980 DOI: 10.1017/S1461145711001544 |
0.33 |
|
| 2012 |
Booij L, Turecki G, Leyton M, Gravel P, Lopez De Lara C, Diksic M, Benkelfat C. Tryptophan hydroxylase(2) gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans. Molecular Psychiatry. 17: 809-17. PMID 21747395 DOI: 10.1038/Mp.2011.79 |
0.321 |
|
| 2012 |
Shakra MA, Pruessner JC, Dagher A, Leyton M, Pihl R. Why gender matters: differential effects of stress and alcohol on cortisol secretion and neural stress circuitry activation among sensation seeking and anxiety-sensitive males and females European Journal of Psychotraumatology. 3. DOI: 10.3402/Ejpt.V3I0.19345 |
0.496 |
|
| 2012 |
Cox SML, Casey KF, Delaney JS, Leyton M. Authors' reply British Journal of Psychiatry. 201: 73-74. DOI: 10.1192/bjp.201.1.73a |
0.457 |
|
| 2011 |
Venugopalan VV, Casey KF, O'Hara C, O'Loughlin J, Benkelfat C, Fellows LK, Leyton M. Acute phenylalanine/tyrosine depletion reduces motivation to smoke cigarettes across stages of addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2469-76. PMID 21775977 DOI: 10.1038/Npp.2011.135 |
0.719 |
|
| 2011 |
Cox SM, Benkelfat C, Dagher A, Delaney JS, Durand F, Kolivakis T, Casey KF, Leyton M. Effects of lowered serotonin transmission on cocaine-induced striatal dopamine response: PET [¹¹C]raclopride study in humans. The British Journal of Psychiatry : the Journal of Mental Science. 199: 391-7. PMID 21543823 DOI: 10.1192/Bjp.Bp.110.084178 |
0.813 |
|
| 2011 |
Setiawan E, Pihl RO, Cox SM, Gianoulakis C, Palmour RM, Benkelfat C, Leyton M. The effect of naltrexone on alcohol's stimulant properties and self-administration behavior in social drinkers: influence of gender and genotype. Alcoholism, Clinical and Experimental Research. 35: 1134-41. PMID 21410481 DOI: 10.1111/J.1530-0277.2011.01446.X |
0.771 |
|
| 2011 |
Berney A, Leyton M, Gravel P, Sibon I, Sookman D, Rosa Neto P, Diksic M, Nakai A, Pinard G, Todorov C, Okazawa H, Blier P, Nordahl TE, Benkelfat C. Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder. Archives of General Psychiatry. 68: 732-41. PMID 21383250 DOI: 10.1001/Archgenpsychiatry.2011.16 |
0.632 |
|
| 2010 |
Allman AA, Benkelfat C, Durand F, Sibon I, Dagher A, Leyton M, Baker GB, O'Driscoll GA. Effect of D-amphetamine on inhibition and motor planning as a function of baseline performance. Psychopharmacology. 211: 423-33. PMID 20602089 DOI: 10.1007/s00213-010-1912-x |
0.656 |
|
| 2010 |
Booij L, Tremblay RE, Leyton M, Séguin JR, Vitaro F, Gravel P, Perreau-Linck E, Lévesque ML, Durand F, Diksic M, Turecki G, Benkelfat C. Brain serotonin synthesis in adult males characterized by physical aggression during childhood: a 21-year longitudinal study. Plos One. 5: e11255. PMID 20582306 DOI: 10.1371/Journal.Pone.0011255 |
0.635 |
|
| 2009 |
Cox SM, Benkelfat C, Dagher A, Delaney JS, Durand F, McKenzie SA, Kolivakis T, Casey KF, Leyton M. Striatal dopamine responses to intranasal cocaine self-administration in humans. Biological Psychiatry. 65: 846-50. PMID 19249751 DOI: 10.1016/J.Biopsych.2009.01.021 |
0.808 |
|
| 2009 |
Flores C, Zawertailo L, Meyer J, Leyton M. The 31st annual meeting of the Canadian College of Neuropsychopharmacology: Toronto, Ontario, June 6-9, 2008. Journal of Psychiatry & Neuroscience : Jpn. 34: 66-7. PMID 19125215 |
0.353 |
|
| 2009 |
Vezina P, Leyton M. Conditioned cues and the expression of stimulant sensitization in animals and humans. Neuropharmacology. 56: 160-8. PMID 18657553 DOI: 10.1016/j.neuropharm.2008.06.070 |
0.641 |
|
| 2008 |
Nagano-Saito A, Leyton M, Monchi O, Goldberg YK, He Y, Dagher A. Dopamine depletion impairs frontostriatal functional connectivity during a set-shifting task. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3697-706. PMID 18385328 DOI: 10.1523/JNEUROSCI.3921-07.2008 |
0.396 |
|
| 2008 |
Barrett SP, Pihl RO, Benkelfat C, Brunelle C, Young SN, Leyton M. The role of dopamine in alcohol self-administration in humans: individual differences. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 18: 439-47. PMID 18367384 DOI: 10.1016/J.Euroneuro.2008.01.008 |
0.808 |
|
| 2007 |
Leyton M. Conditioned and sensitized responses to stimulant drugs in humans. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1601-13. PMID 17888557 DOI: 10.1016/j.pnpbp.2007.08.027 |
0.402 |
|
| 2007 |
Boileau I, Dagher A, Leyton M, Welfeld K, Booij L, Diksic M, Benkelfat C. Conditioned dopamine release in humans: a positron emission tomography [11C]raclopride study with amphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3998-4003. PMID 17428975 DOI: 10.1523/Jneurosci.4370-06.2007 |
0.793 |
|
| 2007 |
Leyton M, aan het Rot M, Booij L, Baker GB, Young SN, Benkelfat C. Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion. Journal of Psychiatry & Neuroscience : Jpn. 32: 129-36. PMID 17353942 |
0.808 |
|
| 2007 |
Rosa-Neto P, Benkelfat C, Sakai Y, Leyton M, Morais JA, Diksic M. Brain regional alpha-[11C]methyl-L-tryptophan trapping, used as an index of 5-HT synthesis, in healthy adults: absence of an age effect. European Journal of Nuclear Medicine and Molecular Imaging. 34: 1254-64. PMID 17318550 DOI: 10.1007/s00259-007-0365-x |
0.617 |
|
| 2007 |
Casey KF, Beninger RJ, Busto U, Tarter RE, Leyton M. The 30th annual meeting of the Canadian College of Neuropsychopharmacology Journal of Psychiatry and Neuroscience. 32: 439-440. |
0.492 |
|
| 2006 |
Boileau I, Dagher A, Leyton M, Gunn RN, Baker GB, Diksic M, Benkelfat C. Modeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men. Archives of General Psychiatry. 63: 1386-95. PMID 17146013 DOI: 10.1001/Archpsyc.63.12.1386 |
0.781 |
|
| 2006 |
Sakai Y, Nishikawa M, Leyton M, Benkelfat C, Young SN, Diksic M. Cortical trapping of alpha-[(11)C]methyl-l-tryptophan, an index of serotonin synthesis, is lower in females than males. Neuroimage. 33: 815-24. PMID 16996279 DOI: 10.1016/J.Neuroimage.2006.08.004 |
0.489 |
|
| 2006 |
Casey KF, Benkelfat C, Young SN, Leyton M. Lack of effect of acute dopamine precursor depletion in nicotine-dependent smokers. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 512-20. PMID 16545549 DOI: 10.1016/J.Euroneuro.2006.02.002 |
0.759 |
|
| 2006 |
Leyton M, Paquette V, Gravel P, Rosa-Neto P, Weston F, Diksic M, Benkelfat C. alpha-[11C]Methyl-L-tryptophan trapping in the orbital and ventral medial prefrontal cortex of suicide attempters. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 16: 220-3. PMID 16269239 DOI: 10.1016/j.euroneuro.2005.09.006 |
0.618 |
|
| 2006 |
Berney A, Sookman D, Leyton M, Young SN, Benkelfat C. Lack of effects on core obsessive-compulsive symptoms of tryptophan depletion during symptom provocation in remitted obsessive-compulsive disorder patients. Biological Psychiatry. 59: 853-7. PMID 16213470 DOI: 10.1016/J.Biopsych.2005.08.023 |
0.673 |
|
| 2006 |
Barrett SP, Tichauer M, Leyton M, Pihl RO. Nicotine increases alcohol self-administration in non-dependent male smokers. Drug and Alcohol Dependence. 81: 197-204. PMID 16054779 DOI: 10.1016/J.Drugalcdep.2005.06.009 |
0.646 |
|
| 2006 |
Boileau I, Dagher A, Welfeld K, Leyton M, Booij L, Sibon I, Diksic M, Benkelfat C. Drug-associated context increases dopamine release during placebo administration: A PET [11C]raclopride study in healthy volunteers Neuroimage. 31: T112. DOI: 10.1016/J.Neuroimage.2006.04.098 |
0.626 |
|
| 2005 |
Leyton M, Casey KF, Delaney JS, Kolivakis T, Benkelfat C. Cocaine craving, euphoria, and self-administration: a preliminary study of the effect of catecholamine precursor depletion. Behavioral Neuroscience. 119: 1619-27. PMID 16420164 DOI: 10.1037/0735-7044.119.6.1619 |
0.747 |
|
| 2005 |
Nishikawa M, Kumakura Y, Young SN, Fiset P, Vogelzangs N, Leyton M, Benkelfat C, Diksic M. Increasing blood oxygen increases an index of 5-HT synthesis in human brain as measured using alpha-[(11)C]methyl-L-tryptophan and positron emission tomography. Neurochemistry International. 47: 556-64. PMID 16157418 DOI: 10.1016/J.Neuint.2005.07.006 |
0.689 |
|
| 2005 |
Rosa-Neto P, Diksic M, Leyton M, Mzengeza S, Benkelfat C. Stability of alpha-[11C]methyl-L-tryptophan brain trapping in healthy male volunteers. European Journal of Nuclear Medicine and Molecular Imaging. 32: 1199-204. PMID 15948006 DOI: 10.1007/s00259-005-1829-5 |
0.613 |
|
| 2005 |
Leyton M, Diksic M, Benkelfat C. Brain regional alpha-[11C]methyl-L-tryptophan trapping correlates with post-mortem tissue serotonin content and [11C]5-hydroxytryptophan accumulation. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 8: 633-4. PMID 15896264 DOI: 10.1017/S1461145705005420 |
0.604 |
|
| 2005 |
Diksic M, Sakai Y, Nishikawa M, Leyton M, Benkelfat C, Young SN. Serotonin synthesis is lower in the cortical areas of female than male healthy participants as measured with α-[11C]methyl-L-tryptophan positron emission tomography Journal of Cerebral Blood Flow & Metabolism. 25: S344-S344. DOI: 10.1038/Sj.Jcbfm.9591524.0344 |
0.491 |
|
| 2004 |
Rosa-Neto P, Diksic M, Okazawa H, Leyton M, Ghadirian N, Mzengeza S, Nakai A, Debonnel G, Blier P, Benkelfat C. Measurement of brain regional alpha-[11C]methyl-L-tryptophan trapping as a measure of serotonin synthesis in medication-free patients with major depression. Archives of General Psychiatry. 61: 556-63. PMID 15184235 DOI: 10.1001/Archpsyc.61.6.556 |
0.626 |
|
| 2004 |
Leyton M, Dagher A, Boileau I, Casey K, Baker GB, Diksic M, Gunn R, Young SN, Benkelfat C. Decreasing amphetamine-induced dopamine release by acute phenylalanine/tyrosine depletion: A PET/[11C]raclopride study in healthy men. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 427-32. PMID 14583741 DOI: 10.1038/Sj.Npp.1300328 |
0.817 |
|
| 2004 |
Barrett SP, Leyton M. Acute phenylalanine/tyrosine depletion: A new method to study the role of catecholamines in psychiatric disorders Primary Psychiatry. 11: 37-41. |
0.484 |
|
| 2003 |
Leyton M, Pun VK, Benkelfat C, Young SN. A new method for rapidly and simultaneously decreasing serotonin and catecholamine synthesis in humans. Journal of Psychiatry & Neuroscience : Jpn. 28: 464-7. PMID 14631457 |
0.657 |
|
| 2003 |
Boileau I, Assaad JM, Pihl RO, Benkelfat C, Leyton M, Diksic M, Tremblay RE, Dagher A. Alcohol promotes dopamine release in the human nucleus accumbens. Synapse (New York, N.Y.). 49: 226-31. PMID 12827641 DOI: 10.1002/Syn.10226 |
0.812 |
|
| 2002 |
Leyton M, Young SN, Srivastava LK. The 25th annual meeting of the Canadian College of Neuropsychopharmacology. Ottawa, Ontario, Canada, June 9-12, 2002. Journal of Psychiatry & Neuroscience : Jpn. 27: 438-50. PMID 12491577 |
0.365 |
|
| 2002 |
Leyton M, Boileau I, Benkelfat C, Diksic M, Baker G, Dagher A. Amphetamine-induced increases in extracellular dopamine, drug wanting, and novelty seeking: a PET/[11C]raclopride study in healthy men. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 1027-35. PMID 12464459 DOI: 10.1016/S0893-133X(02)00366-4 |
0.78 |
|
| 2002 |
Booij L, Van der Does W, Benkelfat C, Bremner JD, Cowen PJ, Fava M, Gillin C, Leyton M, Moore P, Smith KA, Van der Kloot WA. Predictors of mood response to acute tryptophan depletion. A reanalysis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 852-61. PMID 12431859 DOI: 10.1016/S0893-133X(02)00361-5 |
0.605 |
|
| 2002 |
Young SN, Leyton M. The role of serotonin in human mood and social interaction. Insight from altered tryptophan levels. Pharmacology, Biochemistry, and Behavior. 71: 857-65. PMID 11888576 DOI: 10.1016/S0091-3057(01)00670-0 |
0.513 |
|
| 2002 |
Diksic M, Okazawa S, Nishizawa S, Leyton M, Young S. A decrease in blood tryptophan concentration produces regionally specific changes in brain serotonin synthesis in men and women: A PET study with alpha-[11C]methyl-L-tryptophan European Neuropsychopharmacology. 12: 403-404. DOI: 10.1016/S0924-977X(02)80688-5 |
0.486 |
|
| 2002 |
Benkelfat C, Rosa P, Leyton M, Young S, Mzengeza S, Diksic M. In-vivo measurement of 5HT synthesis capacity in the human brain, using the PET/11 C-αmethyltryptophan method: Clinical applications European Neuropsychopharmacology. 12: 137-138. DOI: 10.1016/S0924-977X(02)80082-7 |
0.487 |
|
| 2001 |
Srivastava LK, Leyton M, Young SN. The 24th Annual Meeting of the Canadian College of Neuropsychopharmacology. Banff, Alberta, Canada, June 17-20, 2001. Journal of Psychiatry & Neuroscience : Jpn. 26: 375-84. PMID 11762205 |
0.365 |
|
| 2001 |
Leyton M, Okazawa H, Diksic M, Paris J, Rosa P, Mzengeza S, Young SN, Blier P, Benkelfat C. Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. The American Journal of Psychiatry. 158: 775-82. PMID 11329401 DOI: 10.1176/Appi.Ajp.158.5.775 |
0.519 |
|
| 2001 |
Boileau U, Benkelfat C, Assad J, Leyton M, Pihl RO, Dagher A. Acute ethanol consumption increases synaptic dopamine in ventral striatum: a PET / 11C-raclopride study in healthy volunteers Neuroimage. 13: 1029. DOI: 10.1016/S1053-8119(01)92363-8 |
0.582 |
|
| 2000 |
Leyton M, Ghadirian AM, Young SN, Palmour RM, Blier P, Helmers KF, Benkelfat C. Depressive relapse following acute tryptophan depletion in patients with major depressive disorder. Journal of Psychopharmacology (Oxford, England). 14: 284-7. PMID 11106310 DOI: 10.1177/026988110001400317 |
0.486 |
|
| 2000 |
Leyton M, Young SN, Blier P, Baker GB, Pihl RO, Benkelfat C. Acute tyrosine depletion and alcohol ingestion in healthy women. Alcoholism, Clinical and Experimental Research. 24: 459-64. PMID 10798581 DOI: 10.1111/J.1530-0277.2000.Tb02012.X |
0.628 |
|
| 2000 |
Leyton M, Young SN, Pihl RO, Etezadi S, Lauze C, Blier P, Baker GB, Benkelfat C. Effects on mood of acute phenylalanine/tyrosine depletion in healthy women. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 52-63. PMID 10633491 DOI: 10.1016/S0893-133X(99)00086-X |
0.636 |
|
| 1999 |
Leyton M, Young SN, Pihl RO, Etezadi S, Lauze C, Blier P, Baker GB, Benkelfat C. A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women. Advances in Experimental Medicine and Biology. 467: 67-71. PMID 10721039 DOI: 10.1007/978-1-4615-4709-9_8 |
0.627 |
|
| 1999 |
Young SN, Leyton M, Benkelfat C. Pet studies of serotonin synthesis in the human brain. Advances in Experimental Medicine and Biology. 467: 11-8. PMID 10721033 DOI: 10.1007/978-1-4615-4709-9_2 |
0.508 |
|
| 1999 |
Benkelfat C, Young SN, Okazawa H, Leyton M, Diksic M. The validity of the PET/alpha-[11C]methyl-L-tryptophan method for measuring rates of serotonin synthesis in the human brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 153-7. PMID 10379530 DOI: 10.1016/S0893-133X(98)00140-7 |
0.467 |
|
| 1997 |
Helmers KF, Danoff D, Steinert Y, Leyton M, Young SN. Stress and depressed mood in medical students, law students, and graduate students at McGill University. Academic Medicine : Journal of the Association of American Medical Colleges. 72: 708-14. PMID 9282148 DOI: 10.1097/00001888-199708000-00018 |
0.428 |
|
| 1997 |
Leyton M, Young SN, Benkelfat C. Relapse of depression after rapid depletion of tryptophan. Lancet. 349: 1840-1. PMID 9269238 DOI: 10.1016/S0140-6736(05)61726-6 |
0.432 |
|
| 1997 |
Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C, Blier P, Diksic M. Differences between males and females in rates of serotonin synthesis in human brain. Proceedings of the National Academy of Sciences of the United States of America. 94: 5308-13. PMID 9144233 DOI: 10.1073/Pnas.94.10.5308 |
0.488 |
|
| 1997 |
Leyton M, Young SN, Blier P, Ellenbogen MA, Palmour RM, Ghadirian AM, Benkelfat C. The effect of tryptophan depletion on mood in medication-free, former patients with major affective disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 294-7. PMID 9094147 DOI: 10.1016/S0893-133X(96)00262-X |
0.474 |
|
| 1997 |
Leyton M, Diksic M, Young S, Okazawa H, Nishizawa S, Paris J, Mzengeza S, Benkelfat C. Brain regional rates of serotonin synthesis in patients with borderline personality disorder: A PET study with α-[11C]methyl-L-tryptophan Biological Psychiatry. 42: 16S. DOI: 10.1016/S0006-3223(97)86918-1 |
0.498 |
|
| 1996 |
Leyton M, Bélanger C, Martial J, Beaulieu S, Corin E, Pecknold J, Kin NM, Meaney M, Thavundayil J, Larue S, Nair NP. Cardiovascular, neuroendocrine, and monoaminergic responses to psychological stressors: possible differences between remitted panic disorder patients and healthy controls. Biological Psychiatry. 40: 353-60. PMID 8874835 DOI: 10.1016/0006-3223(95)00452-1 |
0.45 |
|
| 1996 |
Leyton M, Stewart J. Acute and repeated activation of male sexual behavior by tail pinch: opioid and dopaminergic mechanisms. Physiology & Behavior. 60: 77-85. PMID 8804646 DOI: 10.1016/0031-9384(95)02270-8 |
0.463 |
|
| 1995 |
Leyton M, Corin E, Martial J, Meaney M. Psychotic symptoms and vulnerability to recurrent major depression. Journal of Affective Disorders. 33: 107-15. PMID 7759658 DOI: 10.1016/0165-0327(94)00080-S |
0.431 |
|
| 1992 |
Leyton M, Stewart J. The stimulation of central kappa opioid receptors decreases male sexual behavior and locomotor activity. Brain Research. 594: 56-74. PMID 1334765 DOI: 10.1016/0006-8993(92)91029-E |
0.408 |
|
| 1992 |
Leyton M, Rajabi H, Stewart J. U-50,488H into A10 reduces haloperidol-induced elevations of accumbens dopamine. Neuroreport. 3: 1127-30. PMID 1283534 DOI: 10.1097/00001756-199212000-00024 |
0.55 |
|
| 1990 |
Leyton M, Stewart J. Preexposure to foot-shock sensitizes the locomotor response to subsequent systemic morphine and intra-nucleus accumbens amphetamine. Pharmacology, Biochemistry, and Behavior. 37: 303-10. PMID 2080193 DOI: 10.1016/0091-3057(90)90339-J |
0.435 |
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