Keir C. Neuman, Ph.D. - Publications

Princeton University, Princeton, NJ 
biophysics, single molecules, motor proteins, transcription

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Dittmore A, Silver J, Sarkar SK, Marmer B, Goldberg GI, Neuman KC. Internal strain drives spontaneous periodic buckling in collagen and regulates remodeling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402741 DOI: 10.1073/Pnas.1523228113  1
2016 Seol Y, Strub MP, Neuman KC. Single molecule measurements of DNA helicase activity with magnetic tweezers and t-test based step-finding analysis. Methods (San Diego, Calif.). PMID 27131595 DOI: 10.1016/J.Ymeth.2016.04.030  1
2016 Vecchiarelli AG, Li M, Mizuuchi M, Hwang LC, Seol Y, Neuman KC, Mizuuchi K. Membrane-bound MinDE complex acts as a toggle switch that drives Min oscillation coupled to cytoplasmic depletion of MinD. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884160 DOI: 10.1073/Pnas.1600644113  1
2015 Herbert KM, Sarkar SK, Mills M, Delgado De la Herran HC, Neuman KC, Steitz JA. A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting. Rna (New York, N.Y.). PMID 26683315 DOI: 10.1261/Rna.054684.115  1
2015 Hu L, Vecchiarelli AG, Mizuuchi K, Neuman KC, Liu J. Directed and persistent movement arises from mechanochemistry of the ParA/ParB system. Proceedings of the National Academy of Sciences of the United States of America. PMID 26647183 DOI: 10.1073/Pnas.1505147112  1
2015 Seol Y, Zhang H, Agama K, Lorence N, Pommier Y, Neuman KC. Single-molecule supercoil-relaxation assay as a screening tool to determine the mechanism and efficacy of human topoisomerase IB inhibitors. Molecular Cancer Therapeutics. PMID 26351326 DOI: 10.1158/1535-7163.Mct-15-0454  1
2015 Litwin TR, Solà M, Holt IJ, Neuman KC. A robust assay to measure DNA topology-dependent protein binding affinity. Nucleic Acids Research. 43: e43. PMID 25552413 DOI: 10.1093/Nar/Gku1381  1
2015 Silver J, Li Z, Neuman K. Tethered-bead, immune sandwich assay. Biosensors & Bioelectronics. 63: 117-23. PMID 25064819 DOI: 10.1016/J.Bios.2014.07.011  1
2015 Harami GM, Nagy NT, Martina M, Neuman KC, Kovács M. The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling Scientific Reports. 5. DOI: 10.1038/srep11091  1
2015 Neuman KC, Seol Y. Untwisting and unzipping: Magnetic tweezers based measurements of DNA processing enzymes Optical Trapping Applications, Ota 2015 1
2014 Vecchiarelli AG, Seol Y, Neuman KC, Mizuuchi K. A moving ParA gradient on the nucleoid directs subcellular cargo transport via a chemophoresis force. Bioarchitecture. 4: 154-9. PMID 25759913 DOI: 10.4161/19490992.2014.987581  1
2014 Aldred KJ, Breland EJ, Vlčková V, Strub MP, Neuman KC, Kerns RJ, Osheroff N. Role of the water-metal ion bridge in mediating interactions between quinolones and Escherichia coli topoisomerase IV. Biochemistry. 53: 5558-67. PMID 25115926 DOI: 10.1021/Bi500682E  1
2014 Khiati S, Seol Y, Agama K, Dalla Rosa I, Agrawal S, Fesen K, Zhang H, Neuman KC, Pommier Y. Poisoning of mitochondrial topoisomerase I by lamellarin D. Molecular Pharmacology. 86: 193-9. PMID 24890608 DOI: 10.1124/Mol.114.092833  1
2014 Sarkar SK, Bumb A, Wu X, Sochacki KA, Kellman P, Brechbiel MW, Neuman KC. Wide-field in vivo background free imaging by selective magnetic modulation of nanodiamond fluorescence. Biomedical Optics Express. 5: 1190-202. PMID 24761300 DOI: 10.1364/Boe.5.001190  1
2014 Vecchiarelli AG, Neuman KC, Mizuuchi K. A propagating ATPase gradient drives transport of surface-confined cellular cargo. Proceedings of the National Academy of Sciences of the United States of America. 111: 4880-5. PMID 24567408 DOI: 10.1073/Pnas.1401025111  1
2013 Neuman KC. The tail that wags the dog: topoisomerase IV ParC C-terminal domain controls strand passage activity through multipartite topology-dependent interactions with DNA. Journal of Molecular Biology. 425: 3025-8. PMID 23851170 DOI: 10.1016/J.Jmb.2013.07.004  1
2013 Sarkar SK, Bumb A, Mills M, Neuman KC. SnapShot: single-molecule fluorescence. Cell. 153: 1408-1408.e1. PMID 23746850 DOI: 10.1016/J.Cell.2013.05.024  1
2013 Seol Y, Neuman KC. SnapShot: force spectroscopy and single-molecule manipulation. Cell. 153: 1168-1168.e1. PMID 23706746 DOI: 10.1016/J.Cell.2013.04.047  1
2013 Bumb A, Sarkar SK, Billington N, Brechbiel MW, Neuman KC. Silica encapsulation of fluorescent nanodiamonds for colloidal stability and facile surface functionalization. Journal of the American Chemical Society. 135: 7815-8. PMID 23581827 DOI: 10.1021/Ja4016815  1
2013 Seol Y, Gentry AC, Osheroff N, Neuman KC. Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα. The Journal of Biological Chemistry. 288: 13695-703. PMID 23508957 DOI: 10.1074/Jbc.M112.444745  1
2013 Seol Y, Hardin AH, Strub MP, Charvin G, Neuman KC. Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification. Nucleic Acids Research. 41: 4640-9. PMID 23460205 DOI: 10.1093/Nar/Gkt136  1
2013 Arthur Z. E, Susanta K. S, Neuman KC, Gregory I. G. Matrix Metallopeptidase 9/Gelatinase B Handbook of Proteolytic Enzymes. 1: 754-763. DOI: 10.1016/B978-0-12-382219-2.00157-5  1
2013 Bumb A, Sarkar SK, Brechbiel MW, Neuman KC. A nanodiamond is forever: Functionalizable fluorescent nanodiamonds that do not photobleach or blink for in vitro and in vivo imaging Technical Proceedings of the 2013 Nsti Nanotechnology Conference and Expo, Nsti-Nanotech 2013. 3: 1-4.  1
2012 Seol Y, Zhang H, Pommier Y, Neuman KC. A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 109: 16125-30. PMID 22991469 DOI: 10.1073/Pnas.1206480109  1
2012 Sarkar SK, Marmer B, Goldberg G, Neuman KC. Single-molecule tracking of collagenase on native type I collagen fibrils reveals degradation mechanism. Current Biology : Cb. 22: 1047-56. PMID 22578418 DOI: 10.1016/J.Cub.2012.04.012  1
2011 Bumb A, Sarkar SK, Wu XS, Brechbiel MW, Neuman KC. Quantitative characterization of fluorophores in multi-component nanoprobes by single-molecule fluorescence. Biomedical Optics Express. 2: 2761-9. PMID 22025982 DOI: 10.1364/Boe.2.002761  1
2011 Seol Y, Neuman KC. Magnetic tweezers for single-molecule manipulation. Methods in Molecular Biology (Clifton, N.J.). 783: 265-93. PMID 21909894 DOI: 10.1007/978-1-61779-282-3_15  1
2011 Seol Y, Neuman KC. Single-molecule measurements of topoisomerase activity with magnetic tweezers. Methods in Molecular Biology (Clifton, N.J.). 778: 229-41. PMID 21809210 DOI: 10.1007/978-1-61779-261-8_15  1
2011 Hardin AH, Sarkar SK, Seol Y, Liou GF, Osheroff N, Neuman KC. Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification. Nucleic Acids Research. 39: 5729-43. PMID 21421557 DOI: 10.1093/Nar/Gkr109  1
2011 Pitts SL, Liou GF, Mitchenall LA, Burgin AB, Maxwell A, Neuman KC, Osheroff N. Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV. Nucleic Acids Research. 39: 4808-17. PMID 21300644 DOI: 10.1093/Nar/Gkr018  1
2010 Neuman KC. Evolutionary twist on topoisomerases: conversion of gyrase to topoisomerase IV. Proceedings of the National Academy of Sciences of the United States of America. 107: 22363-4. PMID 21169503 DOI: 10.1073/Pnas.1016041108  1
2010 Neuman KC. Single-molecule measurements of DNA topology and topoisomerases. The Journal of Biological Chemistry. 285: 18967-71. PMID 20382732 DOI: 10.1074/Jbc.R109.092437  1
2009 Neuman KC, Charvin G, Bensimon D, Croquette V. Mechanisms of chiral discrimination by topoisomerase IV. Proceedings of the National Academy of Sciences of the United States of America. 106: 6986-91. PMID 19359479 DOI: 10.1073/Pnas.0900574106  1
2008 Bouthier de la Tour C, Amrani L, Cossard R, Neuman KC, Serre MC, Duguet M. Mutational analysis of the helicase-like domain of Thermotoga maritima reverse gyrase. The Journal of Biological Chemistry. 283: 27395-402. PMID 18614530 DOI: 10.1074/Jbc.M800867200  1
2008 Neuman KC, Nagy A. Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy. Nature Methods. 5: 491-505. PMID 18511917 DOI: 10.1038/Nmeth.1218  1
2007 Neuman KC, Lionnet T, Allemand JF. Single-molecule micromanipulation techniques Annual Review of Materials Research. 37: 33-67. DOI: 10.1146/Annurev.Matsci.37.052506.084336  1
2007 Allemand JF, Bensimon D, Charvin G, Croquette V, Lia G, Lionnet T, Neuman KC, Saleh OA, Yokota H. Studies of DNA-protein interactions at the single molecule level with magnetic tweezers Lecture Notes in Physics. 711: 123-140. DOI: 10.1007/3-540-49522-3_6  1
2006 Dalal RV, Larson MH, Neuman KC, Gelles J, Landick R, Block SM. Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing. Molecular Cell. 23: 231-9. PMID 16857589 DOI: 10.1016/J.Molcel.2006.06.023  1
2006 Herbert KM, La Porta A, Wong BJ, Mooney RA, Neuman KC, Landick R, Block SM. Sequence-resolved detection of pausing by single RNA polymerase molecules. Cell. 125: 1083-94. PMID 16777599 DOI: 10.1016/J.Cell.2006.04.032  1
2005 Neuman KC, Saleh OA, Lionnet T, Lia G, Allemand JF, Bensimon D, Croquette V. Statistical determination of the step size of molecular motors. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 17: S3811-20. PMID 21690726 DOI: 10.1088/0953-8984/17/47/012  1
2005 Neuman KC, Abbondanzieri EA, Block SM. Measurement of the effective focal shift in an optical trap. Optics Letters. 30: 1318-20. PMID 15981519 DOI: 10.1364/Ol.30.001318  1
2005 Neuman K, Dholakia K. Shedding light on life Physics World. 18: 35-37. DOI: 10.1088/2058-7058/18/10/35  1
2004 Neuman KC, Block SM. Optical trapping. The Review of Scientific Instruments. 75: 2787-809. PMID 16878180 DOI: 10.1063/1.1785844  1
2004 Lang MJ, Fordyce PM, Engh AM, Neuman KC, Block SM. Simultaneous, coincident optical trapping and single-molecule fluorescence. Nature Methods. 1: 133-9. PMID 15782176 DOI: 10.1038/Nmeth714  1
2003 Neuman KC, Abbondanzieri EA, Landick R, Gelles J, Block SM. Ubiquitous transcriptional pausing is independent of RNA polymerase backtracking. Cell. 115: 437-47. PMID 14622598 DOI: 10.1016/S0092-8674(03)00845-6  1
1999 Neuman KC, Chadd EH, Liou GF, Bergman K, Block SM. Characterization of photodamage to Escherichia coli in optical traps. Biophysical Journal. 77: 2856-63. PMID 10545383 DOI: 10.1016/S0006-3495(99)77117-1  1
1998 Neuman KC, Liou GF, Block SM, Bergman K. Characterization of photodamage induced by optical tweezers Conference On Lasers and Electro-Optics Europe - Technical Digest. 203-204.  1
1997 Prenner EJ, Lewis RN, Neuman KC, Gruner SM, Kondejewski LH, Hodges RS, McElhaney RN. Nonlamellar phases induced by the interaction of gramicidin S with lipid bilayers. A possible relationship to membrane-disrupting activity. Biochemistry. 36: 7906-16. PMID 9201936 DOI: 10.1021/Bi962785K  1
1996 Perkins WR, Dause RB, Parente RA, Minchey SR, Neuman KC, Gruner SM, Taraschi TF, Janoff AS. Role of lipid polymorphism in pulmonary surfactant. Science (New York, N.Y.). 273: 330-2. PMID 8662513 DOI: 10.1126/Science.273.5273.330  1
1996 Farkas G, Tóth C, Neuman KC, Tittel FK. Wavelength dependence of harmonic generation efficiency at metal surfaces induced by femtosecond Ti: Sapphire laser pulses Optics Communications. 132: 289-294. DOI: 10.1016/0030-4018(96)00353-7  1
1996 Farkas G, Toth C, Neuman KC, Falcone RW, Tittel FK. Spectral dependence of harmonic generation efficiency at metal surfaces Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-Leos. 91-92.  1
1996 Farkas G, Toth C, Neuman KC, Falcone RW, Tittel FK. Spectral dependence of harmonic generation efficiency at metal surfaces Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-Leos. 91-92.  1
1996 Donnelly TD, Ditmire T, Neuman K, Perry MD, Falcone RW. High-order harmonic generation in atom clusters Physical Review Letters. 76: 2472-2475.  1
1995 Gauthier JCJ, Bastiani S, Audebert P, Geindre JP, Neuman K, Donnelly TD, Hoffer M, Falcone RW, Shepherd RL, Price DF, White WE. Femtosecond laser-produced plasma x rays from periodically modulated surface targets Proceedings of Spie - the International Society For Optical Engineering. 2523: 242-253.  1
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