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William J. Greenleaf, Ph.D. - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
biophysics, single molecules, motor proteins, transcription
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83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Limouse C, Smith OK, Jukam D, Fryer KA, Greenleaf WJ, Straight AF. Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactions. Nature Communications. 14: 6073. PMID 37770513 DOI: 10.1038/s41467-023-41848-9  0.311
2023 Horton CA, Alexandari AM, Hayes MGB, Marklund E, Schaepe JM, Aditham AK, Shah N, Suzuki PH, Shrikumar A, Afek A, Greenleaf WJ, Gordân R, Zeitlinger J, Kundaje A, Fordyce PM. Short tandem repeats bind transcription factors to tune eukaryotic gene expression. Science (New York, N.Y.). 381: eadd1250. PMID 37733848 DOI: 10.1126/science.add1250  0.617
2023 Shin JH, Bonilla SL, Denny SK, Greenleaf WJ, Herschlag D. Dissecting the energetic architecture within an RNA tertiary structural motif via high-throughput thermodynamic measurements. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220485120. PMID 36897989 DOI: 10.1073/pnas.2220485120  0.345
2023 Kim SH, Marinov GK, Bagdatli ST, Higashino SI, Shipony Z, Kundaje A, Greenleaf WJ. Simultaneous Single-Cell Profiling of the Transcriptome and Accessible Chromatin Using SHARE-seq. Methods in Molecular Biology (Clifton, N.J.). 2611: 187-230. PMID 36807070 DOI: 10.1007/978-1-0716-2899-7_11  0.317
2023 Marklund E, Ke Y, Greenleaf WJ. High-throughput biochemistry in RNA sequence space: predicting structure and function. Nature Reviews. Genetics. PMID 36635406 DOI: 10.1038/s41576-022-00567-5  0.716
2022 Sadée C, Hagler LD, Becker WR, Jarmoskaite I, Vaidyanathan PP, Denny SK, Greenleaf WJ, Herschlag D. A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4. Nature Communications. 13: 4522. PMID 35927243 DOI: 10.1038/s41467-022-31968-z  0.325
2021 Bonilla SL, Denny SK, Shin JH, Alvarez-Buylla A, Greenleaf WJ, Herschlag D. High-throughput dissection of the thermodynamic and conformational properties of a ubiquitous class of RNA tertiary contact motifs. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34373334 DOI: 10.1073/pnas.2109085118  0.31
2020 Andreasson JOL, Savinov A, Block SM, Greenleaf WJ. Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme. Nature Communications. 11: 1663. PMID 32245964 DOI: 10.1038/S41467-020-15540-1  0.616
2020 Shipony Z, Marinov GK, Swaffer MP, Sinnott-Armstrong NA, Skotheim JM, Kundaje A, Greenleaf WJ. Long-range single-molecule mapping of chromatin accessibility in eukaryotes. Nature Methods. PMID 32042188 DOI: 10.1038/S41592-019-0730-2  0.403
2019 Granja JM, Klemm S, McGinnis LM, Kathiria AS, Mezger A, Corces MR, Parks B, Gars E, Liedtke M, Zheng GXY, Chang HY, Majeti R, Greenleaf WJ. Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia. Nature Biotechnology. PMID 31792411 DOI: 10.1038/S41587-019-0332-7  0.324
2019 Calderon D, Nguyen MLT, Mezger A, Kathiria A, Müller F, Nguyen V, Lescano N, Wu B, Trombetta J, Ribado JV, Knowles DA, Gao Z, Blaeschke F, Parent AV, Burt TD, ... ... Greenleaf WJ, et al. Landscape of stimulation-responsive chromatin across diverse human immune cells. Nature Genetics. PMID 31570894 DOI: 10.1038/S41588-019-0505-9  0.321
2019 Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, ... ... Greenleaf WJ, et al. Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. Nature Communications. 10: 4063. PMID 31492858 DOI: 10.1038/S41467-019-11955-7  0.329
2019 Satpathy AT, Granja JM, Yost KE, Qi Y, Meschi F, McDermott GP, Olsen BN, Mumbach MR, Pierce SE, Corces MR, Shah P, Bell JC, Jhutty D, Nemec CM, Wang J, ... ... Greenleaf WJ, et al. Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion. Nature Biotechnology. 37: 925-936. PMID 31375813 DOI: 10.1038/S41587-019-0206-Z  0.321
2019 Yesselman JD, Denny SK, Bisaria N, Herschlag D, Greenleaf WJ, Das R. Sequence-dependent RNA helix conformational preferences predictably impact tertiary structure formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31375637 DOI: 10.1073/Pnas.1901530116  0.442
2019 Ghosh RP, Shi Q, Yang L, Reddick MP, Nikitina T, Zhurkin VB, Fordyce P, Stasevich TJ, Chang HY, Greenleaf WJ, Liphardt JT. Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions. Nature Communications. 10: 3221. PMID 31324780 DOI: 10.1038/S41467-019-11118-8  0.649
2019 Becker WR, Ober-Reynolds B, Jouravleva K, Jolly SM, Zamore PD, Greenleaf WJ. High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2. Molecular Cell. PMID 31324449 DOI: 10.1016/J.Molcel.2019.06.012  0.38
2019 Wu MJ, Andreasson JO, Kladwang W, Greenleaf WJ, Das R. Automated design of diverse stand-alone riboswitches. Acs Synthetic Biology. PMID 31298841 DOI: 10.1021/Acssynbio.9B00142  0.388
2019 Shcherbina A, Li J, Narayanan C, Greenleaf W, Kundaje A, Chetty S. Cell cycle dynamics of human pluripotent stem cells primed for differentiation. Stem Cells (Dayton, Ohio). PMID 31135093 DOI: 10.1002/Stem.3041  0.32
2019 Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, ... ... Greenleaf WJ, et al. HiChIRP reveals RNA-associated chromosome conformation. Nature Methods. PMID 31133759 DOI: 10.1038/S41592-019-0407-X  0.422
2019 Jarmoskaite I, Denny SK, Vaidyanathan PP, Becker WR, Andreasson JOL, Layton CJ, Kappel K, Shivashankar V, Sreenivasan R, Das R, Greenleaf WJ, Herschlag D. A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins. Molecular Cell. PMID 31078383 DOI: 10.1016/J.Molcel.2019.04.012  0.449
2019 Kappel K, Jarmoskaite I, Vaidyanathan PP, Greenleaf WJ, Herschlag D, Das R. Blind tests of RNA-protein binding affinity prediction. Proceedings of the National Academy of Sciences of the United States of America. PMID 30962376 DOI: 10.1073/Pnas.1819047116  0.415
2019 Becker WR, Jarmoskaite I, Vaidyanathan PP, Greenleaf WJ, Herschlag D. Demonstration of Protein Cooperativity Mediated by RNA Structure Using the Human Protein PUM2. Rna (New York, N.Y.). PMID 30914482 DOI: 10.1261/Rna.068585.118  0.433
2019 Layton CJ, McMahon PL, Greenleaf WJ. Large-Scale, Quantitative Protein Assays on a High-Throughput DNA Sequencing Chip. Molecular Cell. 73: 1075-1082.e4. PMID 30849388 DOI: 10.1016/J.Molcel.2019.02.019  0.365
2019 Klemm SL, Shipony Z, Greenleaf WJ. Chromatin accessibility and the regulatory epigenome. Nature Reviews. Genetics. PMID 30675018 DOI: 10.1038/S41576-018-0089-8  0.339
2019 Mumbach M, Granja J, Flynn R, Roake C, Satpathy A, Rubin A, Qi Y, Jiang Z, Shams S, Louie B, Guo J, Gennert D, Corces MR, Khavari P, Atianand M, ... ... Greenleaf W, et al. HiChIRP: RNA-centric chromatin conformation Protocol Exchange. DOI: 10.1038/Protex.2019.032  0.404
2018 Rubin AJ, Parker KR, Satpathy AT, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY, Khavari PA. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. PMID 30580963 DOI: 10.1016/J.Cell.2018.11.022  0.413
2018 Boyle EA, Pritchard JK, Greenleaf WJ. High-resolution mapping of cancer cell networks using co-functional interactions. Molecular Systems Biology. 14: e8594. PMID 30573688 DOI: 10.15252/Msb.20188594  0.301
2018 Zviran A, Mor N, Rais Y, Gingold H, Peles S, Chomsky E, Viukov S, Buenrostro JD, Scognamiglio R, Weinberger L, Manor YS, Krupalnik V, Zerbib M, Hezroni H, Jaitin DA, ... ... Greenleaf WJ, et al. Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules. Cell Stem Cell. PMID 30554962 DOI: 10.1016/J.Stem.2018.11.014  0.345
2018 Chen X, Litzenburger UM, Wei Y, Schep AN, LaGory EL, Choudhry H, Giaccia AJ, Greenleaf WJ, Chang HY. Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. Nature Communications. 9: 4590. PMID 30389926 DOI: 10.1038/S41467-018-07115-Y  0.341
2018 Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Greenleaf WJ, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/Science.Aav1898  0.313
2018 Denny SK, Greenleaf WJ. Linking RNA Sequence, Structure, and Function on Massively Parallel High-Throughput Sequencers. Cold Spring Harbor Perspectives in Biology. PMID 30322887 DOI: 10.1101/Cshperspect.A032300  0.452
2018 Mezger A, Klemm S, Mann I, Brower K, Mir A, Bostick M, Farmer A, Fordyce P, Linnarsson S, Greenleaf W. High-throughput chromatin accessibility profiling at single-cell resolution. Nature Communications. 9: 3647. PMID 30194434 DOI: 10.1038/S41467-018-05887-X  0.634
2018 Mor N, Rais Y, Sheban D, Peles S, Aguilera-Castrejon A, Zviran A, Elinger D, Viukov S, Geula S, Krupalnik V, Zerbib M, Chomsky E, Lasman L, Shani T, Bayerl J, ... ... Greenleaf WJ, et al. Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency. Cell Stem Cell. PMID 30122475 DOI: 10.1016/J.Stem.2018.07.004  0.308
2018 Denny SK, Bisaria N, Yesselman JD, Das R, Herschlag D, Greenleaf WJ. High-Throughput Investigation of Diverse Junction Elements in RNA Tertiary Folding. Cell. PMID 29961580 DOI: 10.1016/J.Cell.2018.05.038  0.428
2018 Zamanighomi M, Lin Z, Daley T, Chen X, Duren Z, Schep A, Greenleaf WJ, Wong WH. Unsupervised clustering and epigenetic classification of single cells. Nature Communications. 9: 2410. PMID 29925875 DOI: 10.1038/S41467-018-04629-3  0.313
2018 Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ. Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation. Cell. PMID 29706549 DOI: 10.1016/J.Cell.2018.03.074  0.367
2018 Bell JC, Jukam D, Teran NA, Risca VI, Smith OK, Johnson WL, Skotheim JM, Greenleaf WJ, Straight AF. Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts. Elife. 7. PMID 29648534 DOI: 10.7554/Elife.27024  0.456
2018 Aggeli D, Karas VO, Sinnott-Armstrong NA, Varghese V, Shafer RW, Greenleaf WJ, Sherlock G. Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery. Nucleic Acids Research. PMID 29361139 DOI: 10.1093/Nar/Gky022  0.37
2018 Bell JC, Jukam D, Teran NA, Risca VI, Smith OK, Johnson WL, Skotheim JM, Greenleaf WJ, Straight AF. Author response: Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts Elife. DOI: 10.7554/Elife.27024.037  0.427
2017 Daugherty AC, Yeo RW, Buenrostro JD, Greenleaf WJ, Kundaje A, Brunet A. Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans. Genome Research. PMID 29141961 DOI: 10.1101/Gr.226233.117  0.324
2017 Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Greenleaf WJ, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963  0.311
2017 Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, ... ... Greenleaf WJ, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. PMID 28854172 DOI: 10.1038/Nature23875  0.326
2017 Schep AN, Wu B, Buenrostro JD, Greenleaf WJ. chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data. Nature Methods. PMID 28825706 DOI: 10.1038/Nmeth.4401  0.335
2017 Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, et al. Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature Genetics. PMID 28805829 DOI: 10.1038/Ng.3935  0.31
2017 Boyle EA, Andreasson JOL, Chircus LM, Sternberg SH, Wu MJ, Guegler CK, Doudna JA, Greenleaf WJ. High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding. Proceedings of the National Academy of Sciences of the United States of America. PMID 28495970 DOI: 10.1073/Pnas.1700557114  0.399
2017 She R, Chakravarty AK, Layton CJ, Chircus LM, Andreasson JO, Damaraju N, McMahon PL, Buenrostro JD, Jarosz DF, Greenleaf WJ. Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28325876 DOI: 10.1073/Pnas.1618370114  0.472
2017 Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR. TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nature Structural & Molecular Biology. PMID 28250416 DOI: 10.1038/Nsmb.3384  0.336
2017 Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY. Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells. Nature Genetics. PMID 28112738 DOI: 10.1038/Ng.3769  0.341
2017 Kappel K, Jarmoskaite I, Vaidyanathan PP, Greenleaf WJ, Herschlag D, Das R. Blind Predictions of RNA/Protein Relative Binding Affinities Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.434  0.402
2016 Risca VI, Denny SK, Straight AF, Greenleaf WJ. Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping. Nature. PMID 28024297 DOI: 10.1038/Nature20781  0.355
2016 Wang J, Yu J, Yang Q, McDermott J, Scott A, Vukovich M, Lagrois R, Gong Q, Greenleaf W, Eisenstein M, Ferguson BS, Soh HT. Multiparameter Particle Display (MPPD): A Quantitative Screening Method for the Discovery of Highly Specific Aptamers. Angewandte Chemie (International Ed. in English). PMID 27933702 DOI: 10.1002/Anie.201608880  0.326
2016 Chen X, Shen Y, Draper W, Buenrostro JD, Litzenburger U, Cho SW, Satpathy AT, Carter AC, Ghosh RP, East-Seletsky A, Doudna JA, Greenleaf WJ, Liphardt JT, Chang HY. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nature Methods. PMID 27749837 DOI: 10.1038/Nmeth.4031  0.335
2016 Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nature Genetics. PMID 27526324 DOI: 10.1038/Ng.3646  0.316
2016 Denny SK, Yang D, Chuang CH, Brady JJ, Lim JS, Grüner BM, Chiou SH, Schep AN, Baral J, Hamard C, Antoine M, Wislez M, Kong CS, Connolly AJ, Park KS, ... ... Greenleaf WJ, et al. Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility. Cell. PMID 27374332 DOI: 10.1016/J.Cell.2016.05.052  0.317
2016 Risca VI, Denny SJ, Schep AN, Kathiria AS, Straight AF, Greenleaf WJ. Mapping of Nucleosomes and DNA-Bound Proteins in Living Cells with Ionizing Radiation Biophysical Journal. 110: 69a. DOI: 10.1016/J.Bpj.2015.11.436  0.397
2016 Risca VI, Denny S, Schep A, Straight A, Greenleaf WJ. Genome-Wide Mapping of Chromatin Secondary Structure using Ionizing Radiation Coupled with Sequencing Biophysical Journal. 110: 66a. DOI: 10.1016/J.Bpj.2015.11.421  0.404
2016 Denny S, Bisaria N, Yesselman J, Das R, Herschlag D, Greenleaf W. High Throughput Characterization of RNA Tertiary Elements Biophysical Journal. 110: 363a. DOI: 10.1016/J.Bpj.2015.11.1957  0.424
2015 Risca VI, Greenleaf WJ. Beyond the Linear Genome: Paired-End Sequencing as a Biophysical Tool. Trends in Cell Biology. PMID 26437592 DOI: 10.1016/J.Tcb.2015.08.004  0.376
2015 Schep AN, Buenrostro JD, Denny SK, Schwartz K, Sherlock G, Greenleaf WJ. Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions. Genome Research. PMID 26314830 DOI: 10.1101/Gr.192294.115  0.367
2015 Qu K, Zaba LC, Giresi PG, Li R, Longmire M, Kim YH, Greenleaf WJ, Chang HY. Individuality and variation of personal regulomes in primary human T cells. Cell Systems. 1: 51-61. PMID 26251845 DOI: 10.1016/J.Cels.2015.06.003  0.3
2015 Buenrostro JD, Wu B, Litzenburger UM, Ruff D, Gonzales ML, Snyder MP, Chang HY, Greenleaf WJ. Single-cell chromatin accessibility reveals principles of regulatory variation. Nature. 523: 486-90. PMID 26083756 DOI: 10.1038/Nature14590  0.361
2015 Risca VI, Greenleaf WJ. Unraveling the 3D genome: genomics tools for multiscale exploration. Trends in Genetics : Tig. 31: 357-72. PMID 25887733 DOI: 10.1016/J.Tig.2015.03.010  0.303
2015 Buenrostro JD, Wu B, Chang HY, Greenleaf WJ. ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 109: 21.29.1-9. PMID 25559105 DOI: 10.1002/0471142727.Mb2129S109  0.344
2015 Greenleaf WJ. Assaying the epigenome in limited numbers of cells. Methods (San Diego, Calif.). 72: 51-6. PMID 25461774 DOI: 10.1016/J.Ymeth.2014.10.010  0.357
2015 Araya CL, Cenik C, Reuter J, Snyder M, Greenleaf W. Abstract B2-42: Systematic dissection of multi-scale mutational hotspots across 21 cancer types reveals a rich landscape of functionally targeted oncogenic disruptions Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B2-42  0.303
2014 Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science (New York, N.Y.). 344: 1042-7. PMID 24789973 DOI: 10.1126/Science.1251871  0.619
2014 Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, Greenleaf WJ. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nature Biotechnology. 32: 562-8. PMID 24727714 DOI: 10.1038/Nbt.2880  0.467
2014 Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of Native Chromatin for Fast and Sensitive Mulitmodal Analysis of Chromatin Architecture Biophysical Journal. 106: 77a. DOI: 10.1016/J.Bpj.2013.11.503  0.398
2014 Buenrostro JD, Chircus L, Araya CL, Layton C, Greenleaf WJ. Direct, High-Throughput Measurement of Quantitative RNA Affinity Landscapes Biophysical Journal. 106: 495a. DOI: 10.1016/J.Bpj.2013.11.2771  0.448
2013 Carpenter ML, Buenrostro JD, Valdiosera C, Schroeder H, Allentoft ME, Sikora M, Rasmussen M, Gravel S, Guillén S, Nekhrizov G, Leshtakov K, Dimitrova D, Theodossiev N, Pettener D, Luiselli D, ... ... Greenleaf WJ, et al. Pulling out the 1%: whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries. American Journal of Human Genetics. 93: 852-64. PMID 24568772 DOI: 10.1016/J.Ajhg.2013.10.002  0.354
2013 Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nature Methods. 10: 1213-8. PMID 24097267 DOI: 10.1038/Nmeth.2688  0.38
2011 Sims PA, Greenleaf WJ, Duan H, Xie XS. Fluorogenic DNA sequencing in PDMS microreactors. Nature Methods. 8: 575-80. PMID 21666670 DOI: 10.1038/Nmeth.1629  0.329
2011 Greenleaf WJ, Sims PA, Duan H, Xie XS. Fluorogenic Pyrosequencing in Microreactors Biophysical Journal. 100: 368a. DOI: 10.1016/J.Bpj.2010.12.2198  0.384
2010 Gutiérrez-Medina B, Andreasson JO, Greenleaf WJ, Laporta A, Block SM. An optical apparatus for rotation and trapping. Methods in Enzymology. 475: 377-404. PMID 20627165 DOI: 10.1016/S0076-6879(10)75015-1  0.553
2008 Herbert KM, Greenleaf WJ, Block SM. Single-molecule studies of RNA polymerase: motoring along. Annual Review of Biochemistry. 77: 149-76. PMID 18410247 DOI: 10.1146/Annurev.Biochem.77.073106.100741  0.79
2008 Larson MH, Greenleaf WJ, Landick R, Block SM. Applied force reveals mechanistic and energetic details of transcription termination. Cell. 132: 971-82. PMID 18358810 DOI: 10.1016/J.Cell.2008.01.027  0.631
2008 Greenleaf WJ, Frieda KL, Foster DA, Woodside MT, Block SM. Direct observation of hierarchical folding in single riboswitch aptamers. Science (New York, N.Y.). 319: 630-3. PMID 18174398 DOI: 10.1126/Science.1151298  0.745
2007 Block SM, Larson MH, Greenleaf WJ, Herbert KM, Guydosh NR, Anthony PC. Molecule by molecule, the physics and chemistry of life: SMB 2007. Nature Chemical Biology. 3: 193-7. PMID 17372599 DOI: 10.1038/Nchembio0407-193  0.723
2007 Greenleaf WJ, Woodside MT, Block SM. High-resolution, single-molecule measurements of biomolecular motion. Annual Review of Biophysics and Biomolecular Structure. 36: 171-90. PMID 17328679 DOI: 10.1146/Annurev.Biophys.36.101106.101451  0.692
2007 Greenleaf WJ, Frieda KL, Abbondanzieri EA, Woodside MT, Block SM. High-resolution, single-molecule optical trapping measurements of transcription with basepair accuracy: Instrumentation and methods Proceedings of Spie - the International Society For Optical Engineering. 6644. DOI: 10.1117/12.739631  0.755
2006 Greenleaf WJ, Block SM. Single-molecule, motion-based DNA sequencing using RNA polymerase. Science (New York, N.Y.). 313: 801. PMID 16902131 DOI: 10.1126/Science.1130105  0.639
2005 Greenleaf WJ, Woodside MT, Abbondanzieri EA, Block SM. Passive all-optical force clamp for high-resolution laser trapping. Physical Review Letters. 95: 208102. PMID 16384102 DOI: 10.1103/Physrevlett.95.208102  0.74
2005 Abbondanzieri EA, Greenleaf WJ, Shaevitz JW, Landick R, Block SM. Direct observation of base-pair stepping by RNA polymerase. Nature. 438: 460-5. PMID 16284617 DOI: 10.1038/Nature04268  0.785
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