Derrek P. Hibar, Ph.D. - Related publications

Biomedical Engineering 0289 University of California, Los Angeles, Los Angeles, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, ... , et al. The genetic architecture of human brainstem structures and their involvement in common brain disorders. Nature Communications. 11: 4016. PMID 32782260 DOI: 10.1038/s41467-020-17376-1   
2020 Zhao L, Batta I, Matloff W, O'Driscoll C, Hobel S, Toga AW. Neuroimaging PheWAS (Phenome-Wide Association Study): A Free Cloud-Computing Platform for Big-Data, Brain-Wide Imaging Association Studies. Neuroinformatics. PMID 32822005 DOI: 10.1007/s12021-020-09486-4   
2020 Hernandez LM, Kim M, Hoftman GD, Haney JR, de la Torre-Ubieta L, Pasaniuc B, Gandal MJ. Transcriptomic Insight Into the Polygenic Mechanisms Underlying Psychiatric Disorders. Biological Psychiatry. PMID 32792264 DOI: 10.1016/j.biopsych.2020.06.005   
2020 Cong S, Yao X, Huang Z, Risacher SL, Nho K, Saykin AJ, Shen L, , . Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data. Neurobiology of Aging. 95: 81-93. PMID 32768867 DOI: 10.1016/j.neurobiolaging.2020.07.005   
2020 Li W, Cai X, Li HJ, Song M, Zhang CY, Yang Y, Zhang L, Zhao L, Liu W, Wang L, Shao M, Zhang Y, Zhang C, Cai J, Zhou DS, et al. Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32791513 DOI: 10.1038/s41386-020-00788-4   
2020 Xiang J, Wang X, Gao Y, Li T, Cao R, Yan T, Ma Y, Niu Y, Xue J, Wang B. Phosphodiesterase 4D Gene Modifies the Functional Network of Patients With Mild Cognitive Impairment and Alzheimer's Disease. Frontiers in Genetics. 11: 890. PMID 32849849 DOI: 10.3389/fgene.2020.00890   
2020 Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, et al. Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants. Science (New York, N.Y.). 369: 561-565. PMID 32732423 DOI: 10.1126/science.aay3983   
2020 Zhao Y, Li T, Zhu H. Bayesian sparse heritability analysis with high-dimensional neuroimaging phenotypes. Biostatistics (Oxford, England). PMID 32948880 DOI: 10.1093/biostatistics/kxaa035   
2020 Matos MR, Ho SM, Schrode N, Brennand KJ. Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics. Molecular and Cellular Neurosciences. 103532. PMID 32712198 DOI: 10.1016/j.mcn.2020.103532   
2020 Li C, Wu D, Lu Q. Set-based genetic association and interaction tests for survival outcomes based on weighted V statistics. Genetic Epidemiology. PMID 32896012 DOI: 10.1002/gepi.22353   
2020 Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, ... , ... , et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/brain/awaa209   
2020 Zhu Y, Ji J, Lin W, Li M, Liu L, Zhu H, Xue F, Li X, Zhou X, Yuan Z. MCC-SP: a powerful integration method for identification of causal pathways from genetic variants to complex disease. Bmc Genetics. 21: 90. PMID 32847502 DOI: 10.1186/s12863-020-00899-3   
2020 Crouch DJM, Bodmer WF. Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants. Proceedings of the National Academy of Sciences of the United States of America. 117: 18924-18933. PMID 32753378 DOI: 10.1073/pnas.2005634117   
2020 Dong X, Su YR, Barfield R, Bien SA, He Q, Harrison TA, Huyghe JR, Keku TO, Lindor NM, Schafmayer C, Chan AT, Gruber SB, Jenkins MA, Kooperberg C, Peters U, et al. A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study. Plos Genetics. 16: e1008947. PMID 32833970 DOI: 10.1371/journal.pgen.1008947   
2020 Wright GEB, Caron NS, Ng B, Casal L, Casazza W, Xu X, Ooi J, Pouladi MA, Mostafavi S, Ross CJD, Hayden MR. Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease. Human Molecular Genetics. PMID 32898862 DOI: 10.1093/hmg/ddaa184   
2020 Crawford H, Scerif G, Wilde L, Beggs A, Stockton J, Sandhu P, Shelley L, Oliver C, McCleery J. Genetic modifiers in rare disorders: the case of fragile X syndrome. European Journal of Human Genetics : Ejhg. PMID 32862204 DOI: 10.1038/s41431-020-00711-x   
2020 Zhang J, Li Y, Dai Y, Xu J. Replication of the Association Between Keratoconus and Polymorphisms in and in a Han Chinese Population. Frontiers in Genetics. 11: 827. PMID 32793291 DOI: 10.3389/fgene.2020.00827   
2020 Hebbar P, Abubaker JA, Abu-Farha M, Alsmadi O, Elkum N, Alkayal F, John SE, Channanath A, Iqbal R, Pitkaniemi J, Tuomilehto J, Sladek R, Al-Mulla F, Thanaraj TA. Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population. Human Genetics. PMID 32902719 DOI: 10.1007/s00439-020-02222-7   
2020 Blatt M, Gusev A, Polyakov Y, Rohloff K, Vaikuntanathan V. Optimized homomorphic encryption solution for secure genome-wide association studies. Bmc Medical Genomics. 13: 83. PMID 32693805 DOI: 10.1186/s12920-020-0719-9   
2020 Höglund A, Strempfl K, Fogelholm J, Wright D, Henriksen R. The genetic regulation of size variation in the transcriptome of the cerebrum in the chicken and its role in domestication and brain size evolution. Bmc Genomics. 21: 518. PMID 32727510 DOI: 10.1186/s12864-020-06908-0   
2020 Grama S, Willcocks I, Hubert JJ, Pardiñas AF, Legge SE, Bracher-Smith M, Menzies GE, Hall LS, Pocklington AJ, Anney RJL, Bray NJ, Escott-Price V, Caseras X. Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort. Translational Psychiatry. 10: 309. PMID 32908133 DOI: 10.1038/s41398-020-00940-0   
2020 French JD, Edwards SL. The Role of Noncoding Variants in Heritable Disease. Trends in Genetics : Tig. PMID 32741549 DOI: 10.1016/j.tig.2020.07.004   
2020 Cheema AN, Pirim D, Wang X, Ali J, Bhatti A, John P, Feingold E, Demirci FY, Kamboh MI. Association Study of Coronary Artery Disease-Associated Genome-Wide Significant SNPs with Coronary Stenosis in Pakistani Population. Disease Markers. 2020: 9738567. PMID 32685059 DOI: 10.1155/2020/9738567   
2020 Zrzavy T, Leutmezer F, Kristoferitsch W, Kornek B, Schneider C, Rommer P, Berger T, Zimprich A. Exome-Sequence Analyses of Four Multi-Incident Multiple Sclerosis Families. Genes. 11. PMID 32854198 DOI: 10.3390/genes11090988   
2020 Sim JJ, Chan FM, Chen S, Meng Tan BH, Mi Aung KM. Achieving GWAS with homomorphic encryption. Bmc Medical Genomics. 13: 90. PMID 32693823 DOI: 10.1186/s12920-020-0717-y   
2020 Meng Q, Wang L, Dai R, Wang J, Ren Z, Liu S, Xia Y, Jiang Y, Duan F, Wang K, Liu C, Chen C. Integrative analyses prioritize GNL3 as a risk gene for bipolar disorder. Molecular Psychiatry. PMID 32826963 DOI: 10.1038/s41380-020-00866-5   
2020 Sun H, Zhang J, Ma Y, Liu J. Integrative genomics analysis identifies 5 promising genes implicated in insomnia risk based on multiple omics datasets. Bioscience Reports. PMID 32830860 DOI: 10.1042/BSR20201084   
2020 Mencacci NE, Reynolds R, Ruiz SG, Vandrovcova J, Forabosco P, Sánchez-Ferrer A, Volpato V, , , Weale ME, Bhatia KP, Webber C, Hardy J, Botía JA, Ryten M. Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders. Brain : a Journal of Neurology. PMID 32889528 DOI: 10.1093/brain/awaa217   
2020 Fergus P, Montanez CC, Abdulaimma B, Lisboa P, Chalmers C, Pineles B. Utilizing Deep Learning and Genome Wide Association Studies for Epistatic-Driven Preterm Birth Classification in African-American Women. Ieee/Acm Transactions On Computational Biology and Bioinformatics. 17: 668-678. PMID 30183645 DOI: 10.1109/TCBB.2018.2868667   
2020 Driver MN, Kuo SI, Dick DM. Genetic feedback for psychiatric conditions: Where are we now and where are we going. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32812348 DOI: 10.1002/ajmg.b.32815   
2020 Gnanadesikan GE, Hare B, Snyder-Mackler N, Call J, Kaminski J, Miklósi Á, MacLean EL. Breed differences in dog cognition associated with brain-expressed genes and neurological functions. Integrative and Comparative Biology. PMID 32726413 DOI: 10.1093/icb/icaa112   
2020 Pandey JP, Olsson J, Weidung B, Kothera RT, Johansson A, Eriksson S, Hallmans G, Elgh F, Lövheim H. An Ig γ Marker Genotype Is a Strong Risk Factor for Alzheimer Disease, Independent of Apolipoprotein E ε4 Genotype. Journal of Immunology (Baltimore, Md. : 1950). PMID 32709662 DOI: 10.4049/jimmunol.2000351   
2020 Guinot F, Szafranski M, Chiquet J, Zancarini A, Le Signor C, Mougel C, Ambroise C. Fast computation of genome-metagenome interaction effects. Algorithms For Molecular Biology : Amb. 15: 13. PMID 32625242 DOI: 10.1186/s13015-020-00173-2   
2020 Wamsley B, Geschwind DH. Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease. Current Opinion in Genetics & Development. 65: 117-125. PMID 32634676 DOI: 10.1016/j.gde.2020.05.032   
2020 Wang H, Zhao L, Liu H, Luo S, Akinyemiju T, Hwang S, Wei Q. Variants in , and in vitamin D pathway genes are associated with breast cancer risk: a large-scale analysis of 14 GWASs in the DRIVE study. American Journal of Cancer Research. 10: 2160-2173. PMID 32775008   
2020 Yousefian-Jazi A, Sung MK, Lee T, Hong YH, Choi JK, Choi J. Functional fine-mapping of noncoding risk variants in amyotrophic lateral sclerosis utilizing convolutional neural network. Scientific Reports. 10: 12872. PMID 32732921 DOI: 10.1038/s41598-020-69790-6   
2020 Liang B, Wang Y, Lin N, Huang H, Chen L, Chen M, Yu D, Chen X, He D, Xu L. Single Nucleotide Polymorphism Array Analysis of 102 Patients with Developmental Delay and/or Intellectual Disability from Fujian, China. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 32858057 DOI: 10.1016/j.cca.2020.08.032   
2020 Xu C, Zhang R, Xia Y, Xiong L, Yang W, Wang P. Annotation of susceptibility SNPs associated with atrial fibrillation. Aging. 12. PMID 32902410 DOI: 10.18632/aging.103615   
2020 Engelbrecht HR, Dalvie S, Agenbag G, Stein DJ, Ramesar RS. Whole-exome sequencing in an Afrikaner family with bipolar disorder. Journal of Affective Disorders. 276: 69-75. PMID 32697718 DOI: 10.1016/j.jad.2020.06.045   
2020 LoPresti M, Beck DB, Duggal P, Cummings DAT, Solomon BD. The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature. American Journal of Human Genetics. 107: 381-402. PMID 32814065 DOI: 10.1016/j.ajhg.2020.08.007   
2020 Vernau KM, Struys E, Letko A, Woolard KD, Aguilar M, Brown EA, Cissell DD, Dickinson PJ, Shelton GD, Broome MR, Gibson KM, Pearl PL, König F, Van Winkle TJ, O'Brien D, et al. A Missense Variant in Associated with Canine Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD) in the Saluki Dog. Genes. 11. PMID 32887425 DOI: 10.3390/genes11091033   
2020 Mahmoudi E, Atkins JR, Quidé Y, Reay WR, Cairns HM, Fitzsimmons C, Carr VJ, Green MJ, Cairns MJ. The MIR137 VNTR rs58335419 Is Associated With Cognitive Impairment in Schizophrenia and Altered Cortical Morphology. Schizophrenia Bulletin. PMID 32910167 DOI: 10.1093/schbul/sbaa123   
2020 Seo GH, Kim T, Choi IH, Park JY, Lee J, Kim S, Won DG, Oh A, Lee Y, Choi J, Lee H, Kang HG, Cho HY, Cho MH, Kim YJ, et al. Diagnostic yield and clinical utility of whole exome sequencing using an automated variant prioritization system, EVIDENCE. Clinical Genetics. PMID 32901917 DOI: 10.1111/cge.13848   
2020 Roberson-Nay R, Lapato DM, Wolen AR, Lancaster EE, Webb BT, Verhulst B, Hettema JM, York TP. An epigenome-wide association study of early-onset major depression in monozygotic twins. Translational Psychiatry. 10: 301. PMID 32843619 DOI: 10.1038/s41398-020-00984-2   
2020 Groopman EE, Povysil G, Goldstein DB, Gharavi AG. Rare genetic causes of complex kidney and urological diseases. Nature Reviews. Nephrology. PMID 32807983 DOI: 10.1038/s41581-020-0325-2   
2020 Horpaopan S, Fann CSJ, Lathrop M, Ott J. Shared genomic segment analysis with equivalence testing. Genetic Epidemiology. PMID 32677112 DOI: 10.1002/gepi.22335   
2020 Li C, Wang L, Li Y, Feng Z, Wang Q, Luo W. Common Variants in Gene Contributed to the Risk of Dilated Cardiomyopathy in the Han Chinese Population. Genetic Testing and Molecular Biomarkers. PMID 32721242 DOI: 10.1089/gtmb.2020.0080   
2020 Baselmans BML, Yengo L, van Rheenen W, Wray NR. Risk in Relatives, Heritability, SNP-Based Heritability, and Genetic Correlations in Psychiatric Disorders: A Review. Biological Psychiatry. PMID 32736793 DOI: 10.1016/j.biopsych.2020.05.034   
2020 Mulvey B, Lagunas T, Dougherty JD. Massively Parallel Reporter Assays: Defining Functional Psychiatric Genetic Variants Across Biological Contexts. Biological Psychiatry. PMID 32843144 DOI: 10.1016/j.biopsych.2020.06.011   
2020 Wainberg M, Magis AT, Earls JC, Lovejoy JC, Sinnott-Armstrong N, Omenn GS, Hood L, Price ND. Multiomic blood correlates of genetic risk identify presymptomatic disease alterations. Proceedings of the National Academy of Sciences of the United States of America. 117: 21813-21820. PMID 32817414 DOI: 10.1073/pnas.2001429117