Lili Wan, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Spinal Muscular Atrophy, RNA binding proteins, Splicing, High-Throughput Screening

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Wan L, Dreyfuss G. Splicing-Correcting Therapy for SMA. Cell. 170: 5. PMID 28666123 DOI: 10.1016/j.cell.2017.06.028  1
2016 Shao D, Lin Y, Liu J, Wan L, Liu Z, Cheng S, Fei L, Deng R, Wang J, Chen X, Liu L, Gu X, Liang W, He P, Wang J, et al. A targeted next-generation sequencing method for identifying clinically relevant mutation profiles in lung adenocarcinoma. Scientific Reports. 6: 22338. PMID 26936516 DOI: 10.1038/srep22338  0.52
2016 Xiao Y, Zhu Y, Yu S, Yan C, J Y Ho R, Liu J, Li T, Wang J, Wan L, Yang X, Xu H, Wang J, Tu X, Jia L. Thirty-day rat toxicity study reveals reversible liver toxicity of mifepristone (RU486) and metapristone. Toxicology Mechanisms and Methods. 1-10. PMID 26907462 DOI: 10.3109/15376516.2015.1118715  0.52
2016 So BR, Wan L, Zhang Z, Li P, Babiash E, Duan J, Younis I, Dreyfuss G. A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange. Nature Structural & Molecular Biology. PMID 26828962 DOI: 10.1038/nsmb.3167  1
2016 Zhang Y, Li H, Wang X, Zheng C, Wang C, Xiao K, Wan L, Jiang X, Guo H. Estimation of submarine groundwater discharge and associated nutrient fluxes in eastern Laizhou Bay, China using 222Rn Journal of Hydrology. 533: 103-113. DOI: 10.1016/j.jhydrol.2015.11.027  0.56
2016 Song D, Wan L, Liu X, Hu W, Xie D, Wang J. Effect of hot pressing temperature on microstructure, mechanical properties and grinding performance of vitrified-metal bond diamond wheels International Journal of Refractory Metals and Hard Materials. 54: 289-294. DOI: 10.1016/j.ijrmhm.2015.08.008  0.52
2015 Feng W, Yang Y, Wan L, Yu C. Tone-Mapped Mean-shift Based Environment Map Sampling. Ieee Transactions On Visualization and Computer Graphics. PMID 26584494 DOI: 10.1109/TVCG.2015.2500236  0.64
2015 Cai W, Wan L, Jiang Y, Wang C, Lin L. The Short-lived Buildings in China: Impacts on Water, Energy and Carbon Emissions. Environmental Science & Technology. PMID 26561867 DOI: 10.1021/acs.est.5b02333  0.56
2015 Dong WL, Wang L, Ding H, Zhao L, Wang D, Wang C, Wan LJ. Substrate Orientation Effect in the On-surface Synthesis of Tetrathiafulvalene Integrated Single-layer Covalent Organic Frameworks. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26467436 DOI: 10.1021/acs.langmuir.5b02412  0.56
2015 Wan L, Dong H, Xu H, Ma J, Zhu Y, Lu Y, Wang J, Zhang T, Li T, Xie J, Xu B, Xie F, Gao Y, Shao J, Tu X, et al. Aspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil. Oncotarget. PMID 26459390 DOI: 10.18632/oncotarget.6038  0.52
2015 Wan L, Zhang Y, Lai Y, Jiang M, Song Y, Zhou J, Zhang Z, Duan X, Fu Y, Liao L, Wang C. Effect of Granulocyte-Macrophage Colony-Stimulating Factor on Prevention and Treatment of Invasive Fungal Disease in Recipients of Allogeneic Stem-Cell Transplantation: A Prospective Multicenter Randomized Phase IV Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26392095 DOI: 10.1200/JCO.2014.60.5121  0.56
2015 Zhou Z, Wan L, Wang C, Zhou K. Integration of Shh and Wnt Signaling Pathways Regulating Hematopoiesis. Dna and Cell Biology. PMID 26378473 DOI: 10.1089/dna.2015.2930  0.56
2015 Zou J, Zhou Z, Wan L, Tong Y, Qin Y, Wang C, Zhou K. Targeting the Sonic Hedgehog-Gli1 Pathway as a Potential New Therapeutic Strategy for Myelodysplastic Syndromes. Plos One. 10: e0136843. PMID 26317501 DOI: 10.1371/journal.pone.0136843  0.56
2015 Yang J, Cai Y, Jiang JL, Wan LP, Yan SK, Wang C. Anti-thymocyte globulin could improve the outcome of allogeneic hematopoietic stem cell transplantation in patients with highly aggressive T-cell tumors. Blood Cancer Journal. 5: e332. PMID 26230956 DOI: 10.1038/bcj.2015.54  0.56
2015 Jiang Y, Wan L, Qin Y, Wang X, Yan S, Xie K, Wang C. Donor Chimerism of B Cells and Nature Killer Cells Provides Useful Information to Predict Hematologic Relapse following Allogeneic Hematopoietic Stem Cell Transplantation. Plos One. 10: e0133671. PMID 26226104 DOI: 10.1371/journal.pone.0133671  0.56
2015 Zhang X, Wan L, Wang J, Xu Y, Li P. [Analysis of related factors of tonsil postoperative pain]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery. 29: 137-9. PMID 25989661  0.52
2015 Feng J, Wang J, Fan P, Jia W, Nie L, Jiang P, Chen X, Lv S, Wan L, Chang S, Li S, Li Y. High-throughput deep sequencing reveals that microRNAs play important roles in salt tolerance of euhalophyte Salicornia europaea. Bmc Plant Biology. 15: 63. PMID 25848810 DOI: 10.1186/s12870-015-0451-3  0.52
2015 Wu Y, Wan L, Li P, Zhang Y, Li M, Gong J, Zhang W. Application of radiofrequency ablation for splenic preservation. The Journal of Surgical Research. 193: 781-7. PMID 25145904 DOI: 10.1016/j.jss.2014.07.031  0.44
2015 Ren Q, Gao T, Li W, Wan L, Hu Y, Peng Y, Sun S, Hu L, Wu M, Guo H, Wang J. A highly enantioselective Michael reaction between α,β-unsaturated ketones and malonic acid half-thioesters New Journal of Chemistry. 39: 5100-5103. DOI: 10.1039/c5nj00719d  0.52
2015 Wang C, Shang J, Lan Y, Tian T, Wang H, Chen X, Gu JY, Liu JZ, Wan LJ, Zhu W, Li G. Metal-organic polyhedra cages immobilized on a plasmonic substrate for sensitive detection of trace explosives Advanced Functional Materials. 25: 6009-6017. DOI: 10.1002/adfm.201503071  0.56
2013 Zhang Z, Pinto AM, Wan L, Wang W, Berg MG, Oliva I, Singh LN, Dengler C, Wei Z, Dreyfuss G. Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: 19348-53. PMID 24191055 DOI: 10.1073/pnas.1319280110  1
2013 Younis I, Dittmar K, Wang W, Foley SW, Berg MG, Hu KY, Wei Z, Wan L, Dreyfuss G. Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA. Elife. 2: e00780. PMID 23908766 DOI: 10.7554/eLife.00780  1
2012 Berg MG, Singh LN, Younis I, Liu Q, Pinto AM, Kaida D, Zhang Z, Cho S, Sherrill-Mix S, Wan L, Dreyfuss G. U1 snRNP determines mRNA length and regulates isoform expression. Cell. 150: 53-64. PMID 22770214 DOI: 10.1016/j.cell.2012.05.029  1
2012 Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G. A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Molecular and Cellular Biology. 32: 1271-83. PMID 22252314 DOI: 10.1128/MCB.05788-11  1
2011 Zhang R, So BR, Li P, Yong J, Glisovic T, Wan L, Dreyfuss G. Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly. Cell. 146: 384-95. PMID 21816274 DOI: 10.1016/j.cell.2011.06.043  1
2010 Kaida D, Berg MG, Younis I, Kasim M, Singh LN, Wan L, Dreyfuss G. U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation. Nature. 468: 664-8. PMID 20881964 DOI: 10.1038/nature09479  1
2010 Yong J, Kasim M, Bachorik JL, Wan L, Dreyfuss G. Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. Molecular Cell. 38: 551-62. PMID 20513430 DOI: 10.1016/j.molcel.2010.03.014  1
2009 Cooper TA, Wan L, Dreyfuss G. RNA and disease. Cell. 136: 777-93. PMID 19239895 DOI: 10.1016/j.cell.2009.02.011  1
2008 Wan L, Ottinger E, Cho S, Dreyfuss G. Inactivation of the SMN complex by oxidative stress. Molecular Cell. 31: 244-54. PMID 18657506 DOI: 10.1016/j.molcel.2008.06.004  1
2008 Zhang Z, Lotti F, Dittmar K, Younis I, Wan L, Kasim M, Dreyfuss G. SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. Cell. 133: 585-600. PMID 18485868 DOI: 10.1016/j.cell.2008.03.031  1
2006 Battle DJ, Kasim M, Yong J, Lotti F, Lau CK, Mouaikel J, Zhang Z, Han K, Wan L, Dreyfuss G. The SMN complex: an assembly machine for RNPs. Cold Spring Harbor Symposia On Quantitative Biology. 71: 313-20. PMID 17381311 DOI: 10.1101/sqb.2006.71.001  1
2006 Battle DJ, Lau CK, Wan L, Deng H, Lotti F, Dreyfuss G. The Gemin5 protein of the SMN complex identifies snRNAs. Molecular Cell. 23: 273-9. PMID 16857593 DOI: 10.1016/j.molcel.2006.05.036  1
2005 Wan L, Battle DJ, Yong J, Gubitz AK, Kolb SJ, Wang J, Dreyfuss G. The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy. Molecular and Cellular Biology. 25: 5543-51. PMID 15964810 DOI: 10.1128/MCB.25.13.5543-5551.2005  1
2005 Feng W, Gubitz AK, Wan L, Battle DJ, Dostie J, Golembe TJ, Dreyfuss G. Gemins modulate the expression and activity of the SMN complex. Human Molecular Genetics. 14: 1605-11. PMID 15843395 DOI: 10.1093/hmg/ddi168  1
2005 Golembe TJ, Yong J, Battle DJ, Feng W, Wan L, Dreyfuss G. Lymphotropic Herpesvirus saimiri uses the SMN complex to assemble Sm cores on its small RNAs. Molecular and Cellular Biology. 25: 602-11. PMID 15632062 DOI: 10.1128/MCB.25.2.602-611.2005  1
2004 Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends in Cell Biology. 14: 226-32. PMID 15130578 DOI: 10.1016/j.tcb.2004.03.010  1
2001 Wan L, Kim JK, Pollard VW, Dreyfuss G. Mutational definition of RNA-binding and protein-protein interaction domains of heterogeneous nuclear RNP C1. The Journal of Biological Chemistry. 276: 7681-8. PMID 11113151 DOI: 10.1074/jbc.M010207200  1
2000 Wan L, Dockendorff TC, Jongens TA, Dreyfuss G. Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Molecular and Cellular Biology. 20: 8536-47. PMID 11046149 DOI: 10.1128/MCB.20.22.8536-8547.2000  1
1999 Kamma H, Horiguchi H, Wan L, Matsui M, Fujiwara M, Fujimoto M, Yazawa T, Dreyfuss G. Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms. Experimental Cell Research. 246: 399-411. PMID 9925756 DOI: 10.1006/excr.1998.4323  1
1998 Siomi MC, Fromont M, Rain JC, Wan L, Wang F, Legrain P, Dreyfuss G. Functional conservation of the transportin nuclear import pathway in divergent organisms. Molecular and Cellular Biology. 18: 4141-8. PMID 9632798  1
1997 Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G. Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins. The Journal of Cell Biology. 138: 1181-92. PMID 9298975 DOI: 10.1083/jcb.138.6.1181  1
1996 Liu Q, Siomi H, Siomi MC, Fischer U, Zhang Y, Wan L, Dreyfuss G. Molecular characterization of the protein products of the fragile X syndrome gene and the survival of motor neurons gene. Cold Spring Harbor Symposia On Quantitative Biology. 61: 689-97. PMID 9246495  1
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