Christopher E. Hart, Ph.D. - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Crooke ST, Baker BF, Kwoh J, Cheng W, Schulz D, Xia S, Salgado N, Bui HH, Hart CE, Burel S, Younis HS, Geary RS, Henry SP, Bhanot S. Integrated Safety Assessment of 2'-O-Methoxyethyl Chimeric Antisense Oligonucleotides in Non-Human Primates and Healthy Human Volunteers. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27357629 DOI: 10.1038/mt.2016.136  0.48
2016 Lima WF, Murray HM, Damle SS, Hart CE, Hung G, De Hoyos CL, Liang XH, Crooke ST. Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function. Nucleic Acids Research. PMID 27131367 DOI: 10.1093/nar/gkw350  0.48
2015 Burel SA, Hart CE, Cauntay P, Hsiao J, Machemer T, Katz M, Watt A, Bui HH, Younis H, Sabripour M, Freier SM, Hung G, Dan A, Prakash TP, Seth PP, et al. Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts. Nucleic Acids Research. PMID 26553810 DOI: 10.1093/nar/gkv1210  0.48
2015 Huang L, Damle SS, Booten S, Singh P, Sabripour M, Hsu J, Jo M, Katz M, Watt A, Hart CE, Freier SM, Monia BP, Guo S. Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration. Plos One. 10: e0132798. PMID 26207833 DOI: 10.1371/journal.pone.0132798  0.48
2014 Wan WB, Migawa MT, Vasquez G, Murray HM, Nichols JG, Gaus H, Berdeja A, Lee S, Hart CE, Lima WF, Swayze EE, Seth PP. Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages. Nucleic Acids Research. 42: 13456-68. PMID 25398895 DOI: 10.1093/nar/gku1115  0.48
2013 Liang XH, Hart CE, Crooke ST. Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells. Biochimica Et Biophysica Acta. 1829: 455-68. PMID 23403288 DOI: 10.1016/j.bbagrm.2013.01.011  0.48
2012 Xu J, Yanagisawa Y, Tsankov AM, Hart C, Aoki K, Kommajosyula N, Steinmann KE, Bochicchio J, Russ C, Regev A, Rando OJ, Nusbaum C, Niki H, Milos P, Weng Z, et al. Genome-wide identification and characterization of replication origins by deep sequencing. Genome Biology. 13: R27. PMID 22531001 DOI: 10.1186/gb-2012-13-4-r27  0.48
2011 Steinmann KE, Hart CE, Thompson JF, Milos PM. Helicos single-molecule sequencing of bacterial genomes. Methods in Molecular Biology (Clifton, N.J.). 733: 3-24. PMID 21431759 DOI: 10.1007/978-1-61779-089-8_1  0.48
2010 Giladi E, Healy J, Myers G, Hart C, Kapranov P, Lipson D, Roels S, Thayer E, Letovsky S. Error tolerant indexing and alignment of short reads with covering template families. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 1397-1411. PMID 20937014  0.48
2010 Kapranov P, Ozsolak F, Kim SW, Foissac S, Lipson D, Hart C, Roels S, Borel C, Antonarakis SE, Monaghan AP, John B, Milos PM. New class of gene-termini-associated human RNAs suggests a novel RNA copying mechanism. Nature. 466: 642-6. PMID 20671709 DOI: 10.1038/nature09190  0.48
2010 Hart C, Lipson D, Ozsolak F, Raz T, Steinmann K, Thompson J, Milos PM. Single-molecule sequencing: sequence methods to enable accurate quantitation Methods in Enzymology. 472: 407-430. PMID 20580974  0.48
2010 Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE. Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA. Nature Methods. 7: 47-9. PMID 19946276 DOI: 10.1038/nmeth.1404  0.48
2010 Giladi E, Healy J, Myers G, Hart C, Kapranov P, Lipson D, Roels S, Thayer E, Letovsky S. Error tolerant indexing and alignment of hort reads with covering template families Journal of Computational Biology. 17: 1279-1293. DOI: 10.1089/cmb.2010.0005  0.48
2009 Ni L, Bruce C, Hart C, Leigh-Bell J, Gelperin D, Umansky L, Gerstein MB, Snyder M. Dynamic and complex transcription factor binding during an inducible response in yeast. Genes & Development. 23: 1351-63. PMID 19487574 DOI: 10.1101/gad.1781909  0.48
2006 Hart CE, Mjolsness E, Wold BJ. Connectivity in the yeast cell cycle transcription network: inferences from neural networks. Plos Computational Biology. 2: e169. PMID 17194216 DOI: 10.1371/journal.pcbi.0020169  0.48
2006 Roden JC, King BW, Trout D, Mortazavi A, Wold BJ, Hart CE. Mining gene expression data by interpreting principal components. Bmc Bioinformatics. 7: 194. PMID 16600052 DOI: 10.1186/1471-2105-7-194  0.48
2005 Hart CE, Sharenbroich L, Bornstein BJ, Trout D, King B, Mjolsness E, Wold BJ. A mathematical and computational framework for quantitative comparison and integration of large-scale gene expression data. Nucleic Acids Research. 33: 2580-94. PMID 15886390 DOI: 10.1093/nar/gki536  0.48
2004 Chudova D, Hart C, Mjolsness E, Smyth P. Gene expression clustering with functional mixture models Advances in Neural Information Processing Systems 0.48
2003 Wang R, Scharenbroich L, Hart C, Wold B, Mjolsness E. Clustering analysis of microarray gene expression data by splitting algorithm Journal of Parallel and Distributed Computing. 63: 692-706. DOI: 10.1016/S0743-7315(03)00085-6  0.48
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