Patrick D. McMullen, Ph.D. - Publications

Chemical and Biological Engineering Northwestern University, Evanston, IL 

13/36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pendse SN, Maertens A, Rosenberg M, Roy D, Fasani RA, Vantangoli MM, Madnick SJ, Boekelheide K, Fornace AJ, Odwin SA, Yager JD, Hartung T, Andersen ME, McMullen PD. Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity. Archives of Toxicology. PMID 27592001 DOI: 10.1007/s00204-016-1824-6  0.6
2015 Black MB, Dodd DE, McMullen PD, Pendse S, MacGregor JA, Gollapudi BB, Andersen ME. Using gene expression profiling to evaluate cellular responses in mouse lungs exposed to V2O5 and a group of other mouse lung tumorigens and non-tumorigens. Regulatory Toxicology and Pharmacology : Rtp. 73: 339-47. PMID 26210822 DOI: 10.1016/j.yrtph.2015.07.017  0.6
2015 Andersen ME, McMullen PD, Krewski D. Developing tools for defining and establishing pathways of toxicity. Archives of Toxicology. 89: 809-12. PMID 25851822 DOI: 10.1007/s00204-015-1512-y  0.6
2015 Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ, Kleensang A, Li H, Livi C, Maertens A, McMullen PD, Rosenberg M, Thomas R, Vantangoli M, Yager JD, et al. The human toxome project. Altex. 32: 112-24. PMID 25742299 DOI:  0.6
2014 Deisenroth C, Black MB, Pendse S, Pluta L, Witherspoon SM, McMullen PD, Thomas RS. MYC is an early response regulator of human adipogenesis in adipose stem cells. Plos One. 9: e114133. PMID 25437437 DOI: 10.1371/journal.pone.0114133  0.6
2014 Clewell RA, Sun B, Adeleye Y, Carmichael P, Efremenko A, McMullen PD, Pendse S, Trask OJ, White A, Andersen ME. Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 56-73. PMID 25078064 DOI: 10.1093/toxsci/kfu153  0.6
2014 McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME. A map of the PPARα transcription regulatory network for primary human hepatocytes. Chemico-Biological Interactions. 209: 14-24. PMID 24269660 DOI: 10.1016/j.cbi.2013.11.006  0.6
2013 Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, ... ... McMullen P, et al. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology. 87: 1315-530. PMID 23974980 DOI: 10.1007/s00204-013-1078-5  0.6
2013 Guisbert E, Czyz DM, Richter K, McMullen PD, Morimoto RI. Identification of a tissue-selective heat shock response regulatory network. Plos Genetics. 9: e1003466. PMID 23637632 DOI: 10.1371/journal.pgen.1003466  0.6
2013 Andersen ME, McMullen PD, Bhattacharya S. Toxicogenomics for transcription factor-governed molecular pathways: moving on to roles beyond classification and prediction. Archives of Toxicology. 87: 7-11. PMID 23184225 DOI: 10.1007/s00204-012-0980-6  0.6
2012 Bhattacharya S, Shoda LK, Zhang Q, Woods CG, Howell BA, Siler SQ, Woodhead JL, Yang Y, McMullen P, Watkins PB, Andersen ME. Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. Frontiers in Physiology. 3: 462. PMID 23248599 DOI: 10.3389/fphys.2012.00462  0.6
2012 McMullen PD, Aprison EZ, Winter PB, Amaral LA, Morimoto RI, Ruvinsky I. Macro-level modeling of the response of C. elegans reproduction to chronic heat stress. Plos Computational Biology. 8: e1002338. PMID 22291584 DOI: 10.1371/journal.pcbi.1002338  0.6
2010 McMullen PD, Morimoto RI, Amaral LA. Physically grounded approach for estimating gene expression from microarray data. Proceedings of the National Academy of Sciences of the United States of America. 107: 13690-5. PMID 20643961 DOI: 10.1073/pnas.1000938107  0.6
Low-probability matches
2019 Nault R, Bals B, Teymouri F, Black MB, Andersen ME, McMullen PD, Krishnan S, Kuravadi N, Paul N, Kumar S, Kannan K, Jayachandra KC, Alagappan L, Patel BD, Bogen KT, et al. A toxicogenomic approach for the risk assessment of the food contaminant acetamide. Toxicology and Applied Pharmacology. 114872. PMID 31881176 DOI: 10.1016/j.taap.2019.114872  0.01
2019 Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK. The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay. Toxicology and Applied Pharmacology. 114774. PMID 31783037 DOI: 10.1016/j.taap.2019.114774  0.01
2019 Andersen ME, McMullen PD, Phillips MB, Yoon M, Pendse SN, Clewell HJ, Hartman JK, Moreau M, Becker RA, Clewell RA. Developing context appropriate toxicity testing approaches using new alternative methods (NAMs). Altex. 36: 523-534. PMID 31664457 DOI: 10.14573/altex.1906261  0.01
2019 McMullen PD, Bhattacharya S, Woods CG, Pendse SN, McBride MT, Soldatow VY, Deisenroth C, LeCluyse EL, Clewell RA, Andersen ME. Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 31628012 DOI: 10.1016/j.tiv.2019.02.017  0.01
2019 McMullen PD, Pendse SN, Black MB, Mansouri K, Haider S, Andersen ME, Clewell RA. Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30807807 DOI: 10.1016/j.tiv.2019.02.014  0.01
2018 Haider S, Black MB, Parks BB, Foley B, Wetmore BA, Andersen ME, Clewell RA, Mansouri K, McMullen PD. A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation. Frontiers in Pharmacology. 9: 1072. PMID 30333746 DOI: 10.3389/fphar.2018.01072  0.01
2018 Wetmore BA, Clewell RA, Cholewa B, Parks B, Pendse SN, Black MB, Mansouri K, Haider S, Berg EL, Judson RS, Houck KA, Martin M, Clewell HJ, Andersen ME, Thomas RS, ... McMullen PD, et al. Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30218698 DOI: 10.1016/j.tiv.2018.09.006  0.01
2018 Hartman JK, Beames T, Parks B, Doheny D, Song G, Efremenko A, Yoon M, Foley B, Deisenroth C, McMullen PD, Clewell RA. An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis. Toxicology and Applied Pharmacology. PMID 29782964 DOI: 10.1016/j.taap.2018.05.016  0.01
2018 Andersen ME, Cruzan G, Black MB, Pendse SN, Dodd DE, Bus JS, Sarang SS, Banton MI, Waites R, Layko DB, McMullen PD. Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment. Regulatory Toxicology and Pharmacology : Rtp. PMID 29777725 DOI: 10.1016/j.yrtph.2018.05.011  0.01
2018 McMullen PD, Andersen ME, Cholewa B, Clewell HJ, Dunnick K, Hartman J, Mansouri K, Minto MS, Nicolas CI, Phillips M, Slattery S, Yoon M, Clewell RA. Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 29391263 DOI: 10.1016/j.tiv.2018.01.027  0.01
2017 Andersen ME, Cruzan G, Black MB, Pendse SN, Dodd D, Bus JS, Sarang S, Banton MI, Waites R, McMullen PD. Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures. Toxicology and Applied Pharmacology. PMID 28951217 DOI: 10.1016/j.taap.2017.09.015  0.01
2017 Miller MM, McMullen PD, Andersen ME, Clewell RA. Multiple receptors shape the estrogen response pathway and are critical considerations for the future of in vitro-based risk assessment efforts. Critical Reviews in Toxicology. 1-17. PMID 28675057 DOI: 10.1080/10408444.2017.1289150  0.01
2017 Andersen ME, Black MB, Campbell JL, Pendse SN, Clewell Iii HJ, Pottenger LH, Bus JS, Dodd DE, Kemp DC, McMullen PD. Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver. Toxicology and Applied Pharmacology. PMID 28392392 DOI: 10.1016/j.taap.2017.04.002  0.01
2016 Clewell RA, McMullen PD, Adeleye Y, Carmichael PL, Andersen ME. Pathway Based Toxicology and Fit-for-Purpose Assays. Advances in Experimental Medicine and Biology. 856: 205-230. PMID 27671724 DOI: 10.1007/978-3-319-33826-2_8  0.01
2015 Fasani RA, Livi CB, Choudhury DR, Kleensang A, Bouhifd M, Pendse SN, McMullen PD, Andersen ME, Hartung T, Rosenberg M. The Human Toxome Collaboratorium: A Shared Environment for Multi-Omic Computational Collaboration within a Consortium. Frontiers in Pharmacology. 6: 322. PMID 26924983 DOI: 10.3389/fphar.2015.00322  0.01
2015 McMullen PD, Freitag NE. Assessing bacterial invasion of cardiac cells in culture and heart colonization in infected mice using Listeria monocytogenes. Journal of Visualized Experiments : Jove. e52497. PMID 26065439 DOI: 10.3791/52497  0.01
2015 Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ, Kleensang A, Li H, Livi C, Maertens A, McMullen PD, Rosenberg M, Thomas R, Vantangoli M, Yager JD, et al. The Human Toxome Project Altex. 32: 112-124. DOI: 10.14573/altex.1502091  0.01
2013 Salazar JK, Wu Z, McMullen PD, Luo Q, Freitag NE, Tortorello ML, Hu S, Zhang W. PrfA-like transcription factor gene lmo0753 contributes to L-rhamnose utilization in Listeria monocytogenes strains associated with human food-borne infections. Applied and Environmental Microbiology. 79: 5584-92. PMID 23835178 DOI: 10.1128/AEM.01812-13  0.01
2013 Frencher JT, Ryan-Pasyeur BK, Huang D, Wang RC, McMullen PD, Letvin NL, Collins WE, Freitag NE, Malkovsky M, Chen CY, Shen L, Chen ZW. SHIV antigen immunization alters patterns of immune responses to SHIV/malaria coinfection and protects against life-threatening SHIV-related malaria. The Journal of Infectious Diseases. 208: 260-70. PMID 23568175 DOI: 10.1093/infdis/jit151  0.01
2012 McMullen PD, Gillaspy AF, Gipson J, Bobo LD, Skiest DJ, Freitag NE. Genome sequence of Listeria monocytogenes 07PF0776, a cardiotropic serovar 4b strain. Journal of Bacteriology. 194: 3552. PMID 22689239 DOI: 10.1128/JB.00616-12  0.01
2011 Alonzo F, McMullen PD, Freitag NE. Actin polymerization drives septation of Listeria monocytogenes namA hydrolase mutants, demonstrating host correction of a bacterial defect. Infection and Immunity. 79: 1458-70. PMID 21263016 DOI: 10.1128/IAI.01140-10  0.01
2009 Sagraves SG, Newell MA, Bard MR, Watkins FR, Corcoran KJ, McMullen PD, Rotondo MF. Tissue oxygenation monitoring in the field: a new EMS vital sign. The Journal of Trauma. 67: 441-3; discussion 44. PMID 19741383 DOI: 10.1097/TA.0b013e3181b88de7  0.01
1980 Brecher G, Anderson RE, McMullen PD. When to do diffs: how often should differential counts be repeated? Blood Cells. 6: 431-54. PMID 7397396  0.01
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