Stanley Appel - Publications

Affiliations: 
Duke University, Durham, NC 

423 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Beers DR, Zhao W, Thonhoff JR, Faridar A, Thome AD, Wen S, Wang J, Appel SH. Serum programmed cell death proteins in amyotrophic lateral sclerosis. Brain, Behavior, & Immunity - Health. 12: 100209. PMID 34589734 DOI: 10.1016/j.bbih.2021.100209  1
2021 Garbuzova-Davis S, Boccio KJ, Llauget A, Shell R, Hailu S, Mustafa H, Ehrhart J, Sanberg PR, Appel SH, Borlongan CV. Beneficial Effects of Transplanted Human Bone Marrow Endothelial Progenitors on Functional and Cellular Components of Blood-Spinal Cord Barrier in ALS Mice. Eneuro. PMID 34479980 DOI: 10.1523/ENEURO.0314-21.2021  1
2021 Berry J, Brooks B, Genge A, Heiman-Patterson T, Appel S, Benatar M, Bowser R, Cudkowicz M, Gooch C, Shefner J, Westra J, Agnese W, Merrill C, Nelson S, Apple S. Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS): Protocol and Study Design. Neurology. Clinical Practice. 11: e472-e479. PMID 34476128 DOI: 10.1212/CPJ.0000000000000968  1
2021 Appel SH, Beers DR, Zhao W. Amyotrophic lateral sclerosis is a systemic disease: peripheral contributions to inflammation-mediated neurodegeneration. Current Opinion in Neurology. PMID 34402459 DOI: 10.1097/WCO.0000000000000983  1
2021 Cathcart SJ, Appel SH, Peterson LE, Greene EP, Powell SZ, Arumanayagam AS, Rivera AL, Cykowski MD. Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord. Journal of Neuropathology and Experimental Neurology. PMID 34383907 DOI: 10.1093/jnen/nlab061  1
2021 Thome AD, Atassi F, Wang J, Faridar A, Zhao W, Thonhoff JR, Beers DR, Lai EC, Appel SH. Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease. Npj Parkinson's Disease. 7: 41. PMID 33986285 DOI: 10.1038/s41531-021-00188-5  1
2021 Pascual B, Funk Q, Zanotti-Fregonara P, Cykowski MD, Veronese M, Rockers E, Bradbury K, Yu M, Nakawah MO, Román GC, Schulz PE, Arumanayagam AS, Beers D, Faridar A, Fujita M, ... Appel SH, et al. Neuroinflammation is highest in areas of disease progression in semantic dementia. Brain : a Journal of Neurology. PMID 33824991 DOI: 10.1093/brain/awab057  1
2021 Garbuzova-Davis S, Boccio KJ, Ehrhart J, Sanberg PR, Appel SH, Borlongan CV. Detection of Endothelial Cell-Associated Human DNA Reveals Transplanted Human Bone Marrow Stem Cell Engraftment into CNS Capillaries of ALS Mice. Brain Research Bulletin. PMID 33545308 DOI: 10.1016/j.brainresbull.2021.01.020  1
2020 Cathcart SJ, Greene EP, Powell SZ, Arumanayagam AS, Rivera AL, Tawil R, Appel SH, Cykowski MD. Spinal Cord and Motor Neuron TDP-43 Pathology in a Sporadic Inclusion Body Myositis Patient. Journal of Neuropathology and Experimental Neurology. 79: 1130-1133. PMID 32954435 DOI: 10.1093/Jnen/Nlaa066  1
2020 Faridar A, Thome AD, Zhao W, Thonhoff JR, Beers DR, Pascual B, Masdeu JC, Appel SH. Restoring regulatory T-cell dysfunction in Alzheimer's disease through expansion. Brain Communications. 2: fcaa112. PMID 32954348 DOI: 10.1093/braincomms/fcaa112  1
2020 Beers DR, Zhao W, Neal DW, Thonhoff JR, Thome AD, Faridar A, Wen S, Wang J, Appel SH. Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis. Scientific Reports. 10: 15295. PMID 32943739 DOI: 10.1038/S41598-020-72247-5  1
2020 Zhao W, Beers DR, Thonhoff JR, Thome AD, Faridar A, Wang J, Wen S, Ornelas L, Sareen D, Goodridge HS, Svendsen CN, Appel SH. Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls. Iscience. 23: 101192. PMID 32521508 DOI: 10.1016/J.Isci.2020.101192  1
2020 Du Y, Zhao W, Thonhoff JR, Wang J, Wen S, Appel SH. Increased activation ability of monocytes from ALS patients. Experimental Neurology. 113259. PMID 32105709 DOI: 10.1016/J.Expneurol.2020.113259  1
2020 Faridar A, Thome A, Zhao W, Thonhoff JR, Beers D, Pascual B, Masdeu JC, Appel S. Restoring dysfunctional regulatory T cells through ex vivo expansion in Alzheimer disease Alzheimer's & Dementia. 16. DOI: 10.1002/alz.039830  0.01
2019 Garbuzova-Davis S, Ehrhart J, Mustafa H, Llauget A, Boccio KJ, Sanberg PR, Appel SH, Borlongan CV. Phenotypic Characteristics of Human Bone Marrow-Derived Endothelial Progenitor Cells in vitro Support Cell Effectiveness for Repair of the Blood-Spinal Cord Barrier in ALS. Brain Research. 146428. PMID 31493389 DOI: 10.1016/J.Brainres.2019.146428  1
2019 Cykowski MD, Dickson DW, Powell SZ, Arumanayagam AS, Rivera AL, Appel SH. Dipeptide repeat (DPR) pathology in the skeletal muscle of ALS patients with C9ORF72 repeat expansion. Acta Neuropathologica. PMID 31375896 DOI: 10.1007/S00401-019-02050-8  1
2019 Pascual B, Funk Q, Zanotti-Fregonara P, Pal N, Rockers E, Yu MM, Spann B, Román GC, Schulz PE, Karmonic C, Appel SH, Masdeu JC. Multimodal F-AV-1451 and MRI findings in non-fluent variant primary progressive aphasia: possible insights on nodal propagation of tau protein across the syntactic network. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31350322 DOI: 10.2967/Jnumed.118.225508  1
2019 Zanotti-Fregonara P, Pascual B, Veronese M, Yu M, Beers D, Appel SH, Masdeu JC. Head-to-head comparison of C-PBR28 and C-ER176 for quantification of the translocator protein in the human brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31152207 DOI: 10.1007/S00259-019-04349-W  1
2019 Garbuzova-Davis S, Kurien C, Haller E, Eve DJ, Navarro S, Steiner G, Mahendrasah A, Hailu S, Khatib M, Boccio KJ, Borlongan CV, Van Loveren HR, Appel SH, Sanberg PR. Human Bone Marrow Endothelial Progenitor Cell Transplantation into Symptomatic ALS Mice Delays Disease Progression and Increases Motor Neuron Survival by Repairing Blood-Spinal Cord Barrier. Scientific Reports. 9: 5280. PMID 30918315 DOI: 10.1038/S41598-019-41747-4  1
2019 Beers DR, Appel SH. Immune dysregulation in amyotrophic lateral sclerosis: mechanisms and emerging therapies. The Lancet. Neurology. 18: 211-220. PMID 30663610 DOI: 10.1016/S1474-4422(18)30394-6  1
2019 Faridar A, Thome A, Zhao W, Pascual B, Victoria A, Dlouhy KG, Beers D, Masdeu JC, Appel S. P2-187: TARGETING ADAPTIVE IMMUNE SYSTEM IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P648-P648. DOI: 10.1016/J.Jalz.2019.06.2594  0.01
2018 Thome AD, Faridar A, Beers DR, Thonhoff JR, Zhao W, Wen S, Pascual B, Masdeu JC, Appel SH. Functional alterations of myeloid cells during the course of Alzheimer's disease. Molecular Neurodegeneration. 13: 61. PMID 30424785 DOI: 10.1186/S13024-018-0293-1  1
2018 Garbuzova-Davis S, Haller E, Navarro S, Besong TE, Boccio KJ, Hailu S, Khatib M, Sanberg PR, Appel SH, Borlongan CV. Transplantation of human bone marrow stem cells into symptomatic ALS mice enhanced structural and functional blood-spinal cord barrier repair. Experimental Neurology. PMID 30172620 DOI: 10.1016/J.Expneurol.2018.08.012  1
2018 Thonhoff JR, Simpson EP, Appel SH. Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis. Current Opinion in Neurology. PMID 30048339 DOI: 10.1097/Wco.0000000000000599  1
2018 Thonhoff JR, Beers DR, Zhao W, Pleitez M, Simpson EP, Berry JD, Cudkowicz ME, Appel SH. Expanded autologous regulatory T-lymphocyte infusions in ALS: A phase I, first-in-human study. Neurology(R) Neuroimmunology & Neuroinflammation. 5: e465. PMID 29845093 DOI: 10.1212/Nxi.0000000000000465  1
2018 Cykowski MD, Powell SZ, Appel JW, Arumanayagam AS, Rivera AL, Appel SH. Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 6: 28. PMID 29653597 DOI: 10.1186/S40478-018-0528-Y  1
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/J.Neuron.2018.02.027  0.01
2018 Beers DR, Zhao W, Appel SH. The Role of Regulatory T Lymphocytes in Amyotrophic Lateral Sclerosis. Jama Neurology. PMID 29507936 DOI: 10.1001/Jamaneurol.2018.0043  1
2018 Zanotti-Fregonara P, Pascual B, Rizzo G, Yu M, Pal N, Beers D, Carter R, Appel S, Atassi N, Masdeu J. Head-to-head comparison of 11C-PBR28 and 18F-GE180 for the quantification of TSPO in the human brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29348317 DOI: 10.2967/Jnumed.117.203109  1
2018 Fournier CN, Schoenfeld D, Berry JD, Cudkowicz ME, Chan J, Quinn C, Brown RH, Salameh JS, Tansey MG, Beers DR, Appel SH, Glass JD. An open label study of a novel immunosuppression intervention for the treatment of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 29308669 DOI: 10.1080/21678421.2017.1421666  1
2017 Miller RG, Appel SH. Introduction to supplement: the current status of treatment for ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 18: 1-4. PMID 28872909 DOI: 10.1080/21678421.2017.1361447  1
2017 Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L. TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss. Neuron. PMID 28669544 DOI: 10.1016/J.Neuron.2017.05.037  1
2017 Berry JD, Paganoni S, Atassi N, Macklin EA, Goyal N, Rivner M, Simpson E, Appel S, Grasso DL, Mejia NI, Mateen F, Gill A, Vieira F, Tassinari V, Perrin S. Phase IIA Trial of Fingolimod for ALS Demonstrates Acceptable Acute Safety and Tolerability. Muscle & Nerve. PMID 28662296 DOI: 10.1002/Mus.25733  1
2017 Cykowski MD, Powell SZ, Peterson LE, Appel JW, Rivera AL, Takei H, Chang E, Appel SH. Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis. Journal of Neuropathology and Experimental Neurology. 76: 402-413. PMID 28521037 DOI: 10.1093/Jnen/Nlx025  1
2017 Lange DJ, Shahbazi M, Silani V, Ludolph AC, Weishaupt JH, Ajroud-Driss S, Fields KG, Remanan R, Appel SH, Morelli C, Doretti A, Maderna L, Messina S, Weiland U, Marklund SL, et al. Pyrimethamine Significantly Lowers CSF/SOD1 in ALS Patients With SOD1 Mutations. Annals of Neurology. PMID 28480639 DOI: 10.1002/Ana.24950  1
2017 Zhao W, Beers DR, Hooten KG, Sieglaff DH, Zhang A, Kalyana-Sundaram S, Traini CM, Halsey WS, Hughes AM, Sathe GM, Livi GP, Fan GH, Appel SH. Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes. Jama Neurology. PMID 28437540 DOI: 10.1001/Jamaneurol.2017.0357  1
2017 Lunetta C, Lizio A, Maestri E, Sansone VA, Mora G, Miller RG, Appel SH, Chiò A. Serum C-Reactive Protein as a Prognostic Biomarker in Amyotrophic Lateral Sclerosis. Jama Neurology. PMID 28384752 DOI: 10.1001/Jamaneurol.2016.6179  1
2017 Beers DR, Zhao W, Wang J, Zhang X, Wen S, Neal D, Thonhoff JR, Alsuliman AS, Shpall EJ, Rezvani K, Appel SH. ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity. Jci Insight. 2: e89530. PMID 28289705 DOI: 10.1172/Jci.Insight.89530  1
2016 Alsuliman A, Appel SH, Beers DR, Basar R, Shaim H, Kaur I, Zulovich J, Yvon E, Muftuoglu M, Imahashi N, Kondo K, Liu E, Shpall EJ, Rezvani K. A robust, good manufacturing practice-compliant, clinical-scale procedure to generate regulatory T cells from patients with amyotrophic lateral sclerosis for adoptive cell therapy. Cytotherapy. PMID 27497700 DOI: 10.1016/J.Jcyt.2016.06.012  1
2016 Appel SH, Armon C. Stem cells in amyotrophic lateral sclerosis: Ready for prime time? Neurology. PMID 27358334 DOI: 10.1212/Wnl.0000000000002906  1
2016 Bali T, Self W, Liu J, Siddique T, Wang LH, Bird TD, Ratti E, Atassi N, Boylan KB, Glass JD, Maragakis NJ, Caress JB, McCluskey LF, Appel SH, Wymer JP, et al. Defining SOD1 ALS natural history to guide therapeutic clinical trial design. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27261500 DOI: 10.1136/Jnnp-2016-313521  1
2016 Staff NP, Appel SH. The immune system continues to knock at the ALS door. Neuromuscular Disorders : Nmd. PMID 27133660 DOI: 10.1016/J.Nmd.2016.04.010  0.01
2016 Samuel BS, Appel SJ. Identifying early signs of peripheral neuropathy among patients with diabetes mellitus. The Nurse Practitioner. 41: 1-5. PMID 26678417 DOI: 10.1097/01.NPR.0000463785.44507.31  1
2016 Cohen OS, Kimiagar I, Korczyn AD, Nitsan Z, Appel S, Hoffmann C, Rosenmann H, Kahana E, Chapman J. Unusual presentations in patients with E200K familial Creutzfeldt-Jakob disease European Journal of Neurology. DOI: 10.1111/ene.12955  1
2015 Agostini M, Appel S, Bellini G, Benziger J, Bick D, Bonfini G, Bravo D, Caccianiga B, Calaprice F, Caminata A, Cavalcante P, Chepurnov A, D'Angelo D, Davini S, Derbin A, et al. Test of Electric Charge Conservation with Borexino. Physical Review Letters. 115: 231802. PMID 26684111 DOI: 10.1103/Physrevlett.115.231802  1
2015 Knies D, Wittmüß P, Appel S, Sawodny O, Ederer M, Feuer R. Modeling and Simulation of Optimal Resource Management during the Diurnal Cycle in Emiliania huxleyi by Genome-Scale Reconstruction and an Extended Flux Balance Analysis Approach. Metabolites. 5: 659-76. PMID 26516924 DOI: 10.3390/metabo5040659  0.01
2015 Karlsen M, Jonsson R, Brun JG, Appel S, Hansen T. TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren's Syndrome Patients by Increased Secretion of Cytokines. Scandinavian Journal of Immunology. 82: 523-31. PMID 26332048 DOI: 10.1111/sji.12368  1
2015 Goldstein JD, Lawrence YR, Appel S, Landau E, Ben-David MA, Rabin T, Benayun M, Dubinski S, Weizman N, Alezra D, Gnessin H, Goldstein AM, Baidun K, Segel MJ, Peled N, et al. Continuous Positive Airway Pressure for Motion Management in Stereotactic Body Radiation Therapy to the Lung: A Controlled Pilot Study. International Journal of Radiation Oncology, Biology, Physics. 93: 391-9. PMID 26264628 DOI: 10.1016/j.ijrobp.2015.06.011  1
2015 Zhao W, Beers DR, Bell S, Wang J, Wen S, Baloh RH, Appel SH. TDP-43 activates microglia through NF-κB and NLRP3 inflammasome. Experimental Neurology. 273: 24-35. PMID 26222336 DOI: 10.1016/J.Expneurol.2015.07.019  1
2015 Gidlund EK, Ydfors M, Appel S, Rundqvist H, Sundberg CJ, Norrbom J. Rapidly elevated levels of PGC-1α-b protein in human skeletal muscle after exercise: exploring regulatory factors in a randomized controlled trial. Journal of Applied Physiology (Bethesda, Md. : 1985). 119: 374-84. PMID 26089547 DOI: 10.1152/japplphysiol.01000.2014  1
2015 Cohen OS, Chapman J, Korczyn AD, Warman-Alaluf N, Nitsan Z, Appel S, Kahana E, Rosenmann H. CSF tau correlates with CJD disease severity and cognitive decline. Acta Neurologica Scandinavica. PMID 26014384 DOI: 10.1111/ane.12441  1
2015 Miller RG, Block G, Katz JS, Barohn RJ, Gopalakrishnan V, Cudkowicz M, Zhang JR, McGrath MS, Ludington E, Appel SH, Azhir A. Randomized phase 2 trial of NP001-a novel immune regulator: Safety and early efficacy in ALS. Neurology® Neuroimmunology & Neuroinflammation. 2: e100. PMID 25884010 DOI: 10.1212/Nxi.0000000000000100  1
2015 Sandvik LF, Skarstein K, Krynitz B, Volchenkov R, Sviland L, Leivestad T, Jonsson R, Appel S. Peritumoral dermis of squamous cell carcinomas in renal transplant recipients contains less CD11c+ myeloid dendritic cells and FoxP3+ T cells compared to immunocompetent controls. Journal of the European Academy of Dermatology and Venereology : Jeadv. PMID 25845701 DOI: 10.1111/jdv.13151  1
2015 Appel S, Sharan AD, Tracy JI, Evans J, Sperling MR. A comparison of occipital and temporal lobe epilepsies. Acta Neurologica Scandinavica. PMID 25809072 DOI: 10.1111/ane.12396  1
2015 Karlsen M, Hansen T, Nordal HH, Brun JG, Jonsson R, Appel S. Expression of Toll-like receptor -7 and -9 in B cell subsets from patients with primary Sjögren's syndrome. Plos One. 10: e0120383. PMID 25790192 DOI: 10.1371/journal.pone.0120383  1
2015 Cirulli ET, Lasseigne BN, Petrovski S, Sapp PC, Dion PA, Leblond CS, Couthouis J, Lu YF, Wang Q, Krueger BJ, Ren Z, Keebler J, Han Y, Levy SE, Boone BE, ... ... Appel S, et al. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. Science (New York, N.Y.). 347: 1436-41. PMID 25700176 DOI: 10.1126/Science.Aaa3650  1
2015 Nüsken E, Herrmann Y, Wohlfarth M, Goecke TW, Appel S, Schneider H, Dötsch J, Nüsken KD. Strong hypoxia reduces leptin synthesis in purified primary human trophoblasts. Placenta. 36: 427-32. PMID 25684657 DOI: 10.1016/j.placenta.2015.01.191  1
2015 McCombs DG, Appel SJ, Ward ME. Expedited diagnosis and management of inpatient hyperosmolar hyperglycemic nonketotic syndrome. Journal of the American Association of Nurse Practitioners. PMID 25641833 DOI: 10.1002/2327-6924.12205  1
2015 Hooten KG, Beers DR, Zhao W, Appel SH. Protective and Toxic Neuroinflammation in Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 364-75. PMID 25567201 DOI: 10.1007/S13311-014-0329-3  1
2015 Cohen OS, Chapman J, Korczyn AD, Nitsan Z, Appel S, Hoffmann C, Rosenmann H, Kahana E, Lee H. Familial Creutzfeldt-Jakob disease with the E200K mutation: longitudinal neuroimaging from asymptomatic to symptomatic CJD. Journal of Neurology. 262: 604-13. PMID 25522698 DOI: 10.1007/s00415-014-7615-1  1
2015 Cohen OS, Chapman J, Korczyn AD, Warman-Alaluf N, Orlev Y, Givaty G, Nitsan Z, Appel S, Rosenmann H, Kahana E, Shechter-Amir D. Characterization of sleep disorders in patients with E200K familial Creutzfeldt-Jakob disease. Journal of Neurology. 262: 443-50. PMID 25451855 DOI: 10.1007/s00415-014-7593-3  1
2015 Appel S, Turnwald EM, Ankerne J, Wohlfarth M, Appel J, Rother E, Janoschek R, Alejandre Alcazar MA, Schnare M, Meißner U, Dötsch J. Hypoxia-Mediated Soluble Fms-Like Tyrosine Kinase 1 Increase Is Not Attenuated in Interleukin 6-Deficient Mice. Reproductive Sciences (Thousand Oaks, Calif.). 22: 735-42. PMID 25415335 DOI: 10.1177/1933719114557898  1
2015 Sauter A, Mc Duffie Y, Boehm H, Martinez A, Spatz JP, Appel S. Surface-mediated priming during in vitro generation of monocyte-derived dendritic cells. Scandinavian Journal of Immunology. 81: 56-65. PMID 25376441 DOI: 10.1111/sji.12246  1
2015 Falope EO, Appel SJ. Substantive review of the literature of medication treatment of chronic low back pain among adults. Journal of the American Association of Nurse Practitioners. 27: 270-9. PMID 25066498 DOI: 10.1002/2327-6924.12155  1
2015 Barth W, Adonin A, Appel S, Gerhard P, Heilmann M, Heymach F, Hollinger R, Vinzenz W, Vormann H, Yaramyshev S. Heavy ion linac as a high current proton beam injector Physical Review Special Topics - Accelerators and Beams. 18. DOI: 10.1103/PhysRevSTAB.18.050102  1
2015 Agostini M, Appel S, Bellini G, Benziger J, Bick D, Bonfini G, Bravo D, Caccianiga B, Calaprice F, Caminata A, Cavalcante P, Chepurnov A, Choi K, D'Angelo D, Davini S, et al. Spectroscopy of geoneutrinos from 2056 days of Borexino data Physical Review D - Particles, Fields, Gravitation and Cosmology. 92. DOI: 10.1103/Physrevd.92.031101  1
2015 Boine-Frankenheim O, Hofmann I, Struckmeier J, Appel S. Artificial collisions, entropy and emittance growth in computer simulations of intense beams Nuclear Instruments and Methods in Physics Research, Section a: Accelerators, Spectrometers, Detectors and Associated Equipment. 770: 164-168. DOI: 10.1016/j.nima.2014.10.004  1
2015 Zhao W, Beers DR, Bell S, Wang J, Wen S, Baloh RH, Appel SH. TDP-43 activates microglia through NF-κB and NLRP3 inflammasome Experimental Neurology. 273: 24-35. DOI: 10.1016/j.expneurol.2015.07.019  1
2015 Joschko P, Widok AH, Appel S, Greiner S, Albers H, Page B. Modeling and simulation of offshore wind farm O&M processes Environmental Impact Assessment Review. 52: 31-39. DOI: 10.1016/j.eiar.2014.09.009  1
2015 Baiocco P, Ramusat G, Sirbi A, Bouilly T, Lavelle F, Cardone T, Fischer H, Appel S. System driven technology selection for future European launch systems Acta Astronautica. 107: 301-316. DOI: 10.1016/j.actaastro.2014.10.037  1
2015 Herzberg N, Kötter F, Appel S, Stojanovic N. Event modeling and processing in business process management: Preface to the 2nd international workshop on event modeling and processing in business process management (EMoV 2015) Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9382.  1
2014 Cykowski MD, Takei H, Schulz PE, Appel SH, Powell SZ. TDP-43 pathology in the basal forebrain and hypothalamus of patients with amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 2: 171. PMID 25539830 DOI: 10.1186/S40478-014-0171-1  1
2014 Goldstein J, Even-Sapir E, Ben-Haim S, Saad A, Spieler B, Davidson T, Berger R, Weiss I, Appel S, Lawrence YR, Symon Z. Does Choline PET/CT Change the Management of Prostate Cancer Patients With Biochemical Failure? American Journal of Clinical Oncology. PMID 25319322 DOI: 10.1097/COC.0000000000000139  1
2014 Appel S, Chapman J, Cohen OS, Rosenmann H, Nitsan Z, Blatt I. Seizures in E200K familial and sporadic Creutzfeldt-Jakob disease. Acta Neurologica Scandinavica. PMID 25319029 DOI: 10.1111/ane.12304  1
2014 McElhiney M, Rabkin JG, Goetz R, Katz J, Miller RG, Forshew DA, David W, Cudkowicz M, Glass JD, Appel S, Simpson E, Mitsumoto H. Seeking a measure of clinically meaningful change in ALS. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 15: 398-405. PMID 25124889 DOI: 10.3109/21678421.2014.942668  1
2014 Vogelsang P, Karlsen M, Brun JG, Jonsson R, Appel S. Altered phenotype and Stat1 expression in Toll-like receptor 7/8 stimulated monocyte-derived dendritic cells from patients with primary Sjögren's syndrome. Arthritis Research & Therapy. 16: R166. PMID 25113744 DOI: 10.1186/ar4682  1
2014 Vance DE, Fazeli PL, Dodson JE, Ackerman M, Talley M, Appel SJ. The synergistic effects of HIV, diabetes, and aging on cognition: implications for practice and research. The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses. 46: 292-305. PMID 25099061 DOI: 10.1097/Jnn.0000000000000074  1
2014 Pattee GL, Wymer JP, Lomen-Hoerth C, Appel SH, Formella AE, Pope LE. An open-label multicenter study to assess the safety of dextromethorphan/quinidine in patients with pseudobulbar affect associated with a range of underlying neurological conditions. Current Medical Research and Opinion. 30: 2255-65. PMID 25062507 DOI: 10.1185/03007995.2014.940040  1
2014 Appel S, Ankerne J, Appel J, Oberthuer A, Mallmann P, Dötsch J. CNN3 regulates trophoblast invasion and is upregulated by hypoxia in BeWo cells. Plos One. 9: e103216. PMID 25050546 DOI: 10.1371/journal.pone.0103216  1
2014 Appel S, Turnwald EM, Alejandre-Alcazar MA, Ankerne J, Rother E, Janoschek R, Wohlfarth M, Vohlen C, Schnare M, Meißner U, Dötsch J. Leptin does not induce an inflammatory response in the murine placenta. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 46: 384-9. PMID 24591047 DOI: 10.1055/s-0034-1368710  1
2014 Cady J, Koval ED, Benitez BA, Zaidman C, Jockel-Balsarotti J, Allred P, Baloh RH, Ravits J, Simpson E, Appel SH, Pestronk A, Goate AM, Miller TM, Cruchaga C, Harms MB. TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis. Jama Neurology. 71: 449-53. PMID 24535663 DOI: 10.1001/Jamaneurol.2013.6237  1
2014 Bergen PJ, Appel SE. The after-life of drugs: a responsible care initiative for reducing their environmental impact. The Medical Journal of Australia. 200: 83. PMID 24484100 DOI: 10.5694/mja13.11267  1
2014 Sprater F, Azeem W, Appel S. Activation of peroxisome proliferator-activated receptor gamma leads to upregulation of ESE-3 expression in human monocyte-derived dendritic cells. Scandinavian Journal of Immunology. 79: 20-6. PMID 24219556 DOI: 10.1111/sji.12126  1
2014 Sandvik LF, Skarstein K, Sviland L, Svarstad E, Nilsen AE, Leivestad T, Jonsson R, Appel S. CD11c(+) dendritic cells rather than Langerhans cells are reduced in normal skin of immunosuppressed renal transplant recipients. Acta Dermato-Venereologica. 94: 173-8. PMID 23995623 DOI: 10.2340/00015555-1679  1
2014 McElhiney M, Rabkin JG, Goetz R, Katz J, Miller RG, Forshew DA, David W, Cudkowicz M, Glass JD, Appel S, Simpson E, Mitsumoto H. Correction to: 'Seeking a measure of clinically meaningful change in ALS' Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 15: 627. DOI: 10.3109/21678421.2014.964589  1
2014 Appel SU, Botti D, Jamison J, Plant L, Shyr JY, Varshney LR. Predictive analytics can facilitate proactive property vacancy policies for cities Technological Forecasting and Social Change. 89: 161-173. DOI: 10.1016/J.Techfore.2013.08.028  1
2014 Appel S, Kleber P, Frischbier S, Freudenreich T, Buchmann A. Modeling and execution of event stream processing in business processes Information Systems. 46: 140-156. DOI: 10.1016/j.is.2014.04.002  1
2014 Goldstein JD, Lawrence YR, Appel S, Landau E, Ben-David MA, Rabin T, Benayun M, Dubinski S, Weizman N, Alezra D, Gnessin H, Goldstein AM, Baidun K, Segel MJ, Peled N, et al. Continuous Positive Airway Pressure for Motion Management in Stereotactic Body Radiation Therapy to the Lung: A Controlled Pilot Study International Journal of Radiation Oncology Biology Physics. DOI: 10.1016/j.ijrobp.2015.06.011  1
2014 Appel SH, Beers DR, Zhao W. Role of Inflammation in Neurodegenerative Diseases Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders. 380-395. DOI: 10.1016/B978-0-12-398270-4.00025-2  1
2014 Appel S, Volman A, Houben L, Gelbstein Y, Bar Sadan M. Orienting MoS2 flakes into ordered films Journal of Materials Science. 49: 7353-7359. DOI: 10.1007/s10853-014-8471-1  1
2014 Freudenreich T, Appel S, Frischbier S, Buchmann AP. Using policies for handling complexity of event-driven architectures Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8627: 114-129. DOI: 10.1007/978-3-319-09970-5-12  1
2014 Appel SH. Foreword Inflammation in Parkinson's Disease: Scientific and Clinical Aspects. vii-x. DOI: 10.1007/978-3-319-08046-8  1
2014 Appel S, Biskup M. Elastic bedding of buildings for protection against emissions from railroad traffic | Elastische Lagerung von Gebäuden zum Schutz vor Einwirkungen aus Schienenverkehr Bautechnik. 91: 472-480. DOI: 10.1002/bate.201400040  1
2014 Henkel JS, Beers DR, Zhao W, Appel SH. Neuroimmunology of Amyotrophic Lateral Sclerosis Neuroinflammation and Cns Disorders. 185-209. DOI: 10.1002/9781118406557.ch8  1
2013 Sauter A, Richter G, Micoulet A, Martinez A, Spatz JP, Appel S. Effective polyethylene glycol passivation for the inhibition of surface interactions of peripheral blood mononuclear cells and platelets. Biointerphases. 8: 14. PMID 24706127 DOI: 10.1186/1559-4106-8-14  1
2013 Mompoint-Williams D, Watts PI, Appel SJ. Detecting and treating hypoglycemia in patients with diabetes. The Nurse Practitioner. 38: 11-4. PMID 24141544 DOI: 10.1097/01.NPR.0000434230.39865.59  1
2013 Haldorsen K, Bruland O, Appel S, Bolstad AI. Reply to 'comment on no association of primary Sjögren's syndrome with Fcγ receptor gene variants'. Genes and Immunity. 14: 532. PMID 24108103 DOI: 10.1038/gene.2013.51  1
2013 Volchenkov R, Brun JG, Jonsson R, Appel S. In vitro suppression of immune responses using monocyte-derived tolerogenic dendritic cells from patients with primary Sjögren's syndrome. Arthritis Research & Therapy. 15: R114. PMID 24025795 DOI: 10.1186/ar4294  1
2013 Appel SH. Special issue: A tribute to Jenny S. Henkel, Ph.D. (1955-2013). Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 757-1047. PMID 23900591 DOI: 10.1007/S11481-013-9492-2  1
2013 Zhao W, Beers DR, Appel SH. Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 888-99. PMID 23881705 DOI: 10.1007/S11481-013-9489-X  1
2013 Sandvik LF, Volchenkov R, Jonsson R, Appel S. Characterization of monocyte-derived dendritic cells from immunosuppressed renal transplant recipients with and without squamous cell carcinomas. Scandinavian Journal of Immunology. 78: 291-7. PMID 23790073 DOI: 10.1111/sji.12084  1
2013 Beecher GP, Appel SJ. An algorithm for care: managing type 2 diabetes. Nursing. 43: 14-7. PMID 23685686 DOI: 10.1097/01.NURSE.0000427993.46812.c3  1
2013 Ravits J, Appel S, Baloh RH, Barohn R, Brooks BR, Elman L, Floeter MK, Henderson C, Lomen-Hoerth C, Macklis JD, McCluskey L, Mitsumoto H, Przedborski S, Rothstein J, Trojanowski JQ, et al. Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 5-18. PMID 23678876 DOI: 10.3109/21678421.2013.778548  1
2013 H Yi D, Appel S. Current status and future perspectives of dendritic cell-based cancer immunotherapy. Scandinavian Journal of Immunology. 78: 167-71. PMID 23672402 DOI: 10.1111/sji.12060  1
2013 Haldorsen K, Appel S, Le Hellard S, Bruland O, Brun JG, Omdal R, Kristjansdottir G, Theander E, Fernandes CP, Kvarnström M, Eriksson P, Rönnblom L, Herlenius MW, Nordmark G, Jonsson R, et al. No association of primary Sjögren's syndrome with Fcγ receptor gene variants. Genes and Immunity. 14: 234-7. PMID 23552400 DOI: 10.1038/gene.2013.12  1
2013 Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, et al. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. The Lancet. Neurology. 12: 435-42. PMID 23541756 DOI: 10.1016/S1474-4422(13)70061-9  1
2013 Volchenkov R, Karlsen M, Jonsson R, Appel S. Type 1 regulatory T cells and regulatory B cells induced by tolerogenic dendritic cells. Scandinavian Journal of Immunology. 77: 246-54. PMID 23442246 DOI: 10.1111/sji.12039  1
2013 Buckley A, Wingert K, Swedo S, Thurm A, Sato S, Appel S, Rodriguez AJ. First night effect analysis in a cohort of young children with autism spectrum disorder. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 9: 67-70. PMID 23319907 DOI: 10.5664/jcsm.2344  1
2013 Henkel JS, Beers DR, Wen S, Rivera AL, Toennis KM, Appel JE, Zhao W, Moore DH, Powell SZ, Appel SH. Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival. Embo Molecular Medicine. 5: 64-79. PMID 23143995 DOI: 10.1002/Emmm.201201544  1
2013 Winkler EA, Sengillo JD, Sullivan JS, Henkel JS, Appel SH, Zlokovic BV. Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis. Acta Neuropathologica. 125: 111-20. PMID 22941226 DOI: 10.1007/S00401-012-1039-8  1
2013 Fröbel S, Appel S, Ganter C, Gilch P. Extracting picosecond time constants from steady-state spectroscopy: A physical chemistry experiment Journal of Chemical Education. 90: 1082-1086. DOI: 10.1021/Ed4001393  1
2013 Appel S, Frischbier S, Freudenreich T, Buchmann A. Event stream processing units in business processes Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8094: 187-202. DOI: 10.1007/978-3-642-40176-3_15  1
2013 Freudenreich T, Eugster P, Frischbier S, Appel S, Buchmann A. Implementing federated object systems Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7920: 230-254. DOI: 10.1007/978-3-642-39038-8-10  1
2013 Nabeel M, Appel S, Bertino E, Buchmann A. Privacy preserving context aware publish subscribe systems Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7873: 465-478. DOI: 10.1007/978-3-642-38631-2_34  1
2012 Sprater F, Hovden AO, Appel S. Expression of ESE-3 isoforms in immunogenic and tolerogenic human monocyte-derived dendritic cells. Plos One. 7: e49577. PMID 23185370 DOI: 10.1371/journal.pone.0049577  1
2012 Appel SJ, Jones SJ. Latent autoimmune diabetes of adulthood: a case presentation. The Nurse Practitioner. 37: 6-9. PMID 23014173 DOI: 10.1097/01.NPR.0000419302.54267.d8  1
2012 Appel SH, Rowland LP. Amyotrophic lateral sclerosis, frontotemporal lobar dementia, and p62: a functional convergence? Neurology. 79: 1526-7. PMID 22972643 DOI: 10.1212/Wnl.0B013E31826E26Ec  1
2012 Appel S, Otto SJ, Weese JS. Cystotomy practices and complications among general small animal practitioners in Ontario, Canada. The Canadian Veterinary Journal. La Revue Vã©Tã©Rinaire Canadienne. 53: 303-10. PMID 22942449  1
2012 Jones EJ, Appel SJ, Eaves YD, Moneyham L, Oster RA, Ovalle F. Cardiometabolic risk, knowledge, risk perception, and self-efficacy among American Indian women with previous gestational diabetes. Journal of Obstetric, Gynecologic, and Neonatal Nursing : Jognn / Naacog. 41: 246-57. PMID 22834848 DOI: 10.1111/J.1552-6909.2012.01339.X  1
2012 Mompoint-Williams D, Watts PI, Appel SJ. Detecting and treating hypoglycemia in patients with diabetes. Nursing. 42: 50-2. PMID 22832630 DOI: 10.1097/01.NURSE.0000414629.07884.7f  1
2012 Zhao W, Beers DR, Liao B, Henkel JS, Appel SH. Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms. Neurobiology of Disease. 48: 418-28. PMID 22820142 DOI: 10.1016/J.Nbd.2012.07.008  1
2012 Appel SH. Inflammation in Parkinson's disease: cause or consequence? Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1075-7. PMID 22806694 DOI: 10.1002/mds.25111  1
2012 Volchenkov R, Jonsson R, Appel S. Anti-Ro and anti-La autoantibody profiling in Norwegian patients with primary Sjögren's syndrome using luciferase immunoprecipitation systems (LIPS). Scandinavian Journal of Rheumatology. 41: 314-5. PMID 22804348 DOI: 10.3109/03009742.2012.670863  1
2012 Liao B, Zhao W, Beers DR, Henkel JS, Appel SH. Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS. Experimental Neurology. 237: 147-52. PMID 22735487 DOI: 10.1016/J.Expneurol.2012.06.011  1
2012 Cohen OS, Prohovnik I, Korczyn AD, Inzelberg R, Nitsan Z, Appel S, Kahana E, Rosenmann H, Chapman J. Characterization of movement disorders in patients with familial Creutzfeldt-Jakob disease carrying the E200K mutation. The Israel Medical Association Journal : Imaj. 14: 162-5. PMID 22675855  1
2012 Sandvik LF, Vogelsang P, Leivestad T, Jonsson R, Appel S. Quantification of plasmacytoid dendritic cells and type 1 myeloid dendritic cells in peripheral blood of renal transplant recipients with and without squamous cell carcinoma. Acta Dermato-Venereologica. 92: 623-4. PMID 22378032 DOI: 10.2340/00015555-1334  1
2012 Kano O, Beers DR, Henkel JS, Appel SH. Peripheral nerve inflammation in ALS mice: cause or consequence. Neurology. 78: 833-5. PMID 22377817 DOI: 10.1212/Wnl.0B013E318249F776  1
2012 Landsverk OJ, Ottesen AH, Berg-Larsen A, Appel S, Bakke O. Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells. Journal of Leukocyte Biology. 91: 729-37. PMID 22371435 DOI: 10.1189/jlb.0311150  1
2012 Hovden AO, Karlsen M, Jonsson R, Appel S. The bacterial preparation OK432 induces IL-12p70 secretion in human dendritic cells in a TLR3 dependent manner. Plos One. 7: e31217. PMID 22363584 DOI: 10.1371/journal.pone.0031217  1
2012 Appel S, Duke ES, Martinez AR, Khan OI, Dustin IM, Reeves-Tyer P, Berl MB, Sato S, Gaillard WD, Theodore WH. Cerebral blood flow and fMRI BOLD auditory language activation in temporal lobe epilepsy. Epilepsia. 53: 631-8. PMID 22332720 DOI: 10.1111/j.1528-1167.2012.03403.x  1
2012 Alejandre Alcazar MA, Ostreicher I, Appel S, Rother E, Vohlen C, Plank C, Dötsch J. Developmental regulation of inflammatory cytokine-mediated Stat3 signaling: the missing link between intrauterine growth restriction and pulmonary dysfunction? Journal of Molecular Medicine (Berlin, Germany). 90: 945-57. PMID 22271168 DOI: 10.1007/s00109-012-0860-9  1
2012 Cherrington A, Martin MY, Hayes M, Halanych JH, Wright MA, Appel SJ, Andreae SJ, Safford M. Intervention mapping as a guide for the development of a diabetes peer support intervention in rural Alabama. Preventing Chronic Disease. 9: E36. PMID 22239751 DOI: 10.5888/Pcd9.110053  1
2012 Hirvonen J, Kreisl WC, Fujita M, Dustin I, Khan O, Appel S, Zhang Y, Morse C, Pike VW, Innis RB, Theodore WH. Increased in vivo expression of an inflammatory marker in temporal lobe epilepsy. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 234-40. PMID 22238156 DOI: 10.2967/jnumed.111.091694  1
2012 Jensen MH, Watt J, Hodgkinson JL, Gallant C, Appel S, El-Mezgueldi M, Angelini TE, Morgan KG, Lehman W, Moore JR. Effects of basic calponin on the flexural mechanics and stability of F-actin. Cytoskeleton (Hoboken, N.J.). 69: 49-58. PMID 22135101 DOI: 10.1002/Cm.20548  1
2012 Appel SJ. Nurse case management with a therapeutic algorithm for people living with diabetes, hypertension and raised LDL cholesterol: after 1 year 22% of those receiving the intervention have all three parameters under control versus 10% of those receiving usual care. Evidence-Based Nursing. 15: 18-9. PMID 22108564 DOI: 10.1136/ebnurs-2011-100264  1
2012 Volchenkov R, Sprater F, Vogelsang P, Appel S. The 2011 Nobel Prize in physiology or medicine. Scandinavian Journal of Immunology. 75: 1-4. PMID 22053831 DOI: 10.1111/j.1365-3083.2011.02663.x  1
2012 Theodore WH, Wiggs EA, Martinez AR, Dustin IH, Khan OI, Appel S, Reeves-Tyer P, Sato S. Serotonin 1A receptors, depression, and memory in temporal lobe epilepsy. Epilepsia. 53: 129-33. PMID 22050514 DOI: 10.1111/j.1528-1167.2011.03309.x  1
2012 Appel SA, Chapman J, Prohovnik I, Hoffman C, Cohen OS, Blatt I. The EEG in E200K familial CJD: relation to MRI patterns. Journal of Neurology. 259: 491-6. PMID 21833705 DOI: 10.1007/s00415-011-6208-5  1
2012 Freudenreich T, Appel S, Frischbier S, Buchmann AP. ACTrESS - Automatic context transformation in event-based software systems Proceedings of the 6th Acm International Conference On Distributed Event-Based Systems, Debs'12. 179-190. DOI: 10.1145/2335484.2335505  1
2012 Appel S, Frischbier S, Freudenreich T, Buchmann A. Eventlets: Components for the integration of event streams with SOA Proceedings - 2012 5th Ieee International Conference On Service-Oriented Computing and Applications, Soca 2012. DOI: 10.1109/SOCA.2012.6449455  1
2012 Appel S, Boine-Frankenheim O. Microbunch dynamics and multistream instability in a heavy-ion synchrotron Physical Review Special Topics - Accelerators and Beams. 15. DOI: 10.1103/PhysRevSTAB.15.054201  1
2012 Warnock DM, Appel S. Learning the Unwritten Rules: Working Class Students in Graduate School Innovative Higher Education. 37: 307-321. DOI: 10.1007/S10755-011-9204-X  1
2012 Buchmann A, Appel S, Freudenreich T, Frischbier S, Guerrero PE. From calls to events: Architecting future BPM systems Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7481: 17-32. DOI: 10.1007/978-3-642-32885-5_2  1
2012 Henkel JS, Beers DR, Zhao W, Appel SH. Reactive oxygen and nitrogen species - A driving force in amyotrophic lateral sclerosis Systems Biology of Free Radicals and Antioxidants. 3141-3165. DOI: 10.1007/978-3-642-30018-9_131  1
2012 Jaredson D, Ramusat G, Appel S, Cardone T, Persson J, Baiocco P, Lavelle F, Bouilly T. FLPP NGL structural subsytems activity European Space Agency, (Special Publication) Esa Sp. 691.  1
2011 Vaknin I, Kunis G, Miller O, Butovsky O, Bukshpan S, Beers DR, Henkel JS, Yoles E, Appel SH, Schwartz M. Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. Plos One. 6: e26921. PMID 22073221 DOI: 10.1371/Journal.Pone.0026921  1
2011 Gendelman HE, Appel SH. Neuroprotective activities of regulatory T cells. Trends in Molecular Medicine. 17: 687-8. PMID 21996344 DOI: 10.1016/J.Molmed.2011.08.005  1
2011 Appel SH, Zhao W, Beers DR, Henkel JS. The microglial-motoneuron dialogue in ALS. Acta Myologica : Myopathies and Cardiomyopathies : Official Journal of the Mediterranean Society of Myology / Edited by the Gaetano Conte Academy For the Study of Striated Muscle Diseases. 30: 4-8. PMID 21842586  1
2011 Miller RG, Moore DH, Forshew DA, Katz JS, Barohn RJ, Valan M, Bromberg MB, Goslin KL, Graves MC, McCluskey LF, McVey AL, Mozaffar T, Florence JM, Pestronk A, Ross M, ... ... Appel SH, et al. Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: examining a more efficient trial design. Neurology. 77: 973-9. PMID 21813790 DOI: 10.1212/Wnl.0B013E31822Dc7A5  1
2011 Jonsson R, Vogelsang P, Volchenkov R, Espinosa A, Wahren-Herlenius M, Appel S. The complexity of Sjögren's syndrome: novel aspects on pathogenesis. Immunology Letters. 141: 1-9. PMID 21777618 DOI: 10.1016/j.imlet.2011.06.007  1
2011 Lied GA, Vogelsang P, Berstad A, Appel S. Dendritic cell populations in patients with self-reported food hypersensitivity. International Journal of General Medicine. 4: 389-96. PMID 21625415 DOI: 10.2147/IJGM.S17655  1
2011 Beers DR, Henkel JS, Zhao W, Wang J, Huang A, Wen S, Liao B, Appel SH. Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 134: 1293-314. PMID 21596768 DOI: 10.1093/Brain/Awr074  1
2011 Appel S, Le Hellard S, Bruland O, Brun JG, Omdal R, Kristjansdottir G, Theander E, Nordmark G, Kvarnström M, Eriksson P, Rönnblom L, Wahren-Herlenius M, Jonsson R. Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome. Annals of the Rheumatic Diseases. 70: 1327-9. PMID 21450750 DOI: 10.1136/ard.2010.138966  1
2011 Karlsen M, Hovden AO, Vogelsang P, Tysnes BB, Appel S. Bromelain treatment leads to maturation of monocyte-derived dendritic cells but cannot replace PGE2 in a cocktail of IL-1β, IL-6, TNF-α and PGE2. Scandinavian Journal of Immunology. 74: 135-43. PMID 21449940 DOI: 10.1111/j.1365-3083.2011.02562.x  1
2011 Hunt CW, Grant JS, Appel SJ. An integrative review of community health advisors in type 2 diabetes. Journal of Community Health. 36: 883-93. PMID 21344237 DOI: 10.1007/S10900-011-9381-7  1
2011 Appel SJ. Tapping incretin-based therapy for type 2 diabetes. Nursing. 41: 49-51. PMID 21326056 DOI: 10.1097/01.NURSE.0000394397.55390.75  1
2011 Cohen OS, Prohovnik I, Korczyn AD, Ephraty L, Nitsan Z, Tsabari R, Appel S, Rosenmann H, Kahana E, Chapman J. The Creutzfeldt-Jakob disease (CJD) neurological status scale: a new tool for evaluation of disease severity and progression. Acta Neurologica Scandinavica. 124: 368-74. PMID 21303352 DOI: 10.1111/j.1600-0404.2011.01489.x  1
2011 Gallant C, Appel S, Graceffa P, Leavis P, Lin JJ, Gunning PW, Schevzov G, Chaponnier C, DeGnore J, Lehman W, Morgan KG. Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 300: C1356-65. PMID 21289288 DOI: 10.1152/Ajpcell.00450.2010  1
2011 Hovden AO, Karlsen M, Jonsson R, Aarstad HJ, Appel S. Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses. Bmc Immunology. 12: 2. PMID 21208424 DOI: 10.1186/1471-2172-12-2  1
2011 Beers DR, Zhao W, Liao B, Kano O, Wang J, Huang A, Appel SH, Henkel JS. Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice. Brain, Behavior, and Immunity. 25: 1025-35. PMID 21176785 DOI: 10.1016/J.Bbi.2010.12.008  1
2011 Appel SA, Molshatzki N, Schwammenthal Y, Merzeliak O, Toashi M, Sela BA, Tanne D. Serum calcium levels and long-term mortality in patients with acute stroke. Cerebrovascular Diseases (Basel, Switzerland). 31: 93-9. PMID 21079398 DOI: 10.1159/000321335  1
2011 Jawaid A, Poon M, Strutt AM, Rice LK, McDowell EJ, Salamone AR, Qureshi SU, Simpson E, Appel SH, York MK, Schulz PE. Does apolipoprotein E genotype modify the clinical expression of ALS? European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 18: 618-24. PMID 20880000 DOI: 10.1111/J.1468-1331.2010.03225.X  1
2011 Nordmark G, Kristjansdottir G, Theander E, Appel S, Eriksson P, Vasaitis L, Kvarnström M, Delaleu N, Lundmark P, Lundmark A, Sjöwall C, Brun JG, Jonsson MV, Harboe E, Gøransson LG, et al. Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome. Genes and Immunity. 12: 100-9. PMID 20861858 DOI: 10.1038/gene.2010.44  1
2011 Cohen OS, Chapman J, Lee H, Nitsan Z, Appel S, Hoffman C, Rosenmann H, Korczyn AD, Prohovnik I. Pruritus in familial Creutzfeldt-Jakob disease: a common symptom associated with central nervous system pathology. Journal of Neurology. 258: 89-95. PMID 20725737 DOI: 10.1007/s00415-010-5694-1  1
2011 Buchmann A, Pfohl HC, Appel S, Freudenreich T, Frischbier S, Petrov I, Zuber C. Event-driven services: Integrating production, logistics and transportation Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6568: 237-241. DOI: 10.1007/978-3-642-19394-1_26  1
2011 Görgen P, Boine-Frankenheim O, Appel S, Dimopoulou C, Litvinov S, Steck M. Experimental studies of beam loss during low energy Operation with electron cooled heavy ions in the ESR Ipac 2011 - 2nd International Particle Accelerator Conference. 3424-3426.  1
2011 Appel S, Brennan B, Davies R, Frost E, Gilbert A, Grogan B, Hooper J, Lloyd A, Morgan K, Newton I, Payne F, Sansom L, Ware J. Pharmacist elders hit out at rogue pharmacy owners: Call for united approach Australian Journal of Pharmacy. 92: 4-5+8.  1
2010 Appel SH, Cwik VA, Day JW. Trauma, TDP-43, and amyotrophic lateral sclerosis. Muscle & Nerve. 42: 851-2. PMID 21104858 DOI: 10.1002/Mus.21939  1
2010 Hovden AO, Appel S. The first dendritic cell-based therapeutic cancer vaccine is approved by the FDA. Scandinavian Journal of Immunology. 72: 554. PMID 21044130 DOI: 10.1111/j.1365-3083.2010.02464.x  1
2010 Hill AN, Appel SJ. Diagnosing diabetes with A1C: implications and considerations for measurement and surrogate markers. The Nurse Practitioner. 35: 16-23; quiz 23-4. PMID 20827232 DOI: 10.1097/01.NPR.0000388206.16357.02  1
2010 Appel S, Morgan KG. Scaffolding proteins and non-proliferative functions of ERK1/2. Communicative & Integrative Biology. 3: 354-6. PMID 20798825 DOI: 10.4161/Cib.3.4.11832  1
2010 Appel SL, Houston DM, Moore AE, Weese JS. Feline urate urolithiasis. The Canadian Veterinary Journal. La Revue Vã©Tã©Rinaire Canadienne. 51: 493-6. PMID 20676290  1
2010 Langston SB, Appel SJ. Smoking cessation: SNUB OUT CAD. The Nurse Practitioner. 35: 42-6. PMID 20299911 DOI: 10.1097/01.NPR.0000369942.62728.5c  1
2010 Appel S, Allen PG, Vetterkind S, Jin JP, Morgan KG. h3/Acidic calponin: an actin-binding protein that controls extracellular signal-regulated kinase 1/2 activity in nonmuscle cells. Molecular Biology of the Cell. 21: 1409-22. PMID 20181831 DOI: 10.1091/Mbc.E09-06-0451  1
2010 Appel SA, Chapman J, Kahana E, Rosenmann H, Prohovnik I, Pras E, Reznik-Wolf H, Cohen OS. Rapidly progressive Creutzfeldt-Jakob disease in patients with Familial Mediterranean Fever. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 17: 861-5. PMID 20113338 DOI: 10.1111/j.1468-1331.2010.02948.x  1
2010 Jawaid A, Salamone AR, Strutt AM, Murthy SB, Wheaton M, McDowell EJ, Simpson E, Appel SH, York MK, Schulz PE. ALS disease onset may occur later in patients with pre-morbid diabetes mellitus. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 17: 733-9. PMID 20074230 DOI: 10.1111/J.1468-1331.2009.02923.X  1
2010 Cudkowicz ME, Katz J, Moore DH, O'Neill G, Glass JD, Mitsumoto H, Appel S, Ravina B, Kieburtz K, Shoulson I, Kaufmann P, Khan J, Simpson E, Shefner J, Levin B, et al. Toward more efficient clinical trials for amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 259-65. PMID 19961263 DOI: 10.3109/17482960903358865  1
2010 Vogelsang P, Brun JG, Oijordsbakken G, Skarstein K, Jonsson R, Appel S. Levels of plasmacytoid dendritic cells and type-2 myeloid dendritic cells are reduced in peripheral blood of patients with primary Sjogren's syndrome. Annals of the Rheumatic Diseases. 69: 1235-8. PMID 19914903 DOI: 10.1136/ard.2009.118158  1
2010 Appel SH, Beers DR, Henkel JS. T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening? Trends in Immunology. 31: 7-17. PMID 19879804 DOI: 10.1016/J.It.2009.09.003  1
2010 Witgert M, Salamone AR, Strutt AM, Jawaid A, Massman PJ, Bradshaw M, Mosnik D, Appel SH, Schulz PE. Frontal-lobe mediated behavioral dysfunction in amyotrophic lateral sclerosis. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 17: 103-10. PMID 19874396 DOI: 10.1111/J.1468-1331.2009.02801.X  1
2010 Sterling LE, Jawaid A, Salamone AR, Murthy SB, Mosnik DM, McDowell E, Wheaton M, Strutt AM, Simpson E, Appel S, Schulz PE. Association between dysarthria and cognitive impairment in ALS: A prospective study. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 46-51. PMID 19722114 DOI: 10.3109/17482960903207997  1
2010 Zhao W, Beers DR, Henkel JS, Zhang W, Urushitani M, Julien JP, Appel SH. Extracellular mutant SOD1 induces microglial-mediated motoneuron injury. Glia. 58: 231-43. PMID 19672969 DOI: 10.1002/Glia.20919  1
2010 Massey CN, Appel SJ, Buchanan KL, Cherrington AL. Improving diabetes care in rural communities: An overview of current initiatives and a call for renewed efforts Clinical Diabetes. 28: 20-27. DOI: 10.2337/Diaclin.28.1.20  1
2010 Appel S, Sachs K, Buchmann A. Towards benchmarking of AMQP Proceedings of the 4th Acm International Conference On Distributed Event-Based Systems, Debs 2010. 99-100. DOI: 10.1145/1827418.1827438  1
2010 Appel S, Sachs K. A logistics workload for event notification middleware Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6462: 312-324. DOI: 10.1007/978-3-642-17226-7_19  1
2010 Sachs K, Appel S, Kounev S, Buchmann A. Benchmarking publish/subscribe-based messaging systems Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6193: 203-214. DOI: 10.1007/978-3-642-14589-6_21  1
2010 Appel S, Sachs K, Buchmann A. Quality of service in event-based systems Ceur Workshop Proceedings. 581.  1
2010 Appel S, Weiland T, Boine-Frankenheim O. Simulation and observation of the space charge induced multi-stream instability of linac micro bunches in the SIS18 synchrotron Ipac 2010 - 1st International Particle Accelerator Conference. 1916-1918.  1
2009 Vogelsang P, Hovden AO, Jonsson R, Appel S. Levels of dendritic cell populations and regulatory T cells vary significantly between two commonly used mouse strains. Scandinavian Journal of Immunology. 70: 541-6. PMID 19906196 DOI: 10.1111/j.1365-3083.2009.02327.x  1
2009 Jones EJ, Roche CC, Appel SJ. A review of the health beliefs and lifestyle behaviors of women with previous gestational diabetes. Journal of Obstetric, Gynecologic, and Neonatal Nursing : Jognn / Naacog. 38: 516-26. PMID 19883473 DOI: 10.1111/J.1552-6909.2009.01051.X  1
2009 Howe CL, Bergstrom RA, Horazdovsky BF. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology. 73: 1247; author reply 1. PMID 19822878 DOI: 10.1212/WNL.0b013e3181b26ae6  1
2009 Henkel JS, Beers DR, Zhao W, Appel SH. Microglia in ALS: the good, the bad, and the resting. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 389-98. PMID 19731042 DOI: 10.1007/S11481-009-9171-5  1
2009 Goldknopf IL, Bryson JK, Strelets I, Quintero S, Sheta EA, Mosqueda M, Park HR, Appel SH, Shill H, Sabbagh M, Chase B, Kaldjian E, Markopoulou K. Abnormal serum concentrations of proteins in Parkinson's disease. Biochemical and Biophysical Research Communications. 389: 321-7. PMID 19723509 DOI: 10.1016/J.Bbrc.2009.08.150  1
2009 Hill AN, Roche C, Appel SJ. Signs of improvement: diabetes update 2009. The Nurse Practitioner. 34: 12-22, quiz 23. PMID 19474626 DOI: 10.1097/01.Npr.0000352283.97228.10  1
2009 Hannibal MC, Ruzzo EK, Miller LR, Betz B, Buchan JG, Knutzen DM, Barnett K, Landsverk ML, Brice A, LeGuern E, Bedford HM, Worrall BB, Lovitt S, Appel SH, Andermann E, et al. SEPT9 gene sequencing analysis reveals recurrent mutations in hereditary neuralgic amyotrophy. Neurology. 72: 1755-9. PMID 19451530 DOI: 10.1212/Wnl.0B013E3181A609E3  1
2009 Henkel JS, Beers DR, Wen S, Bowser R, Appel SH. Decreased mRNA expression of tight junction proteins in lumbar spinal cords of patients with ALS. Neurology. 72: 1614-6. PMID 19414730 DOI: 10.1212/Wnl.0B013E3181A41228  1
2009 Gangopadhyay SS, Kengni E, Appel S, Gallant C, Kim HR, Leavis P, DeGnore J, Morgan KG. Smooth muscle archvillin is an ERK scaffolding protein. The Journal of Biological Chemistry. 284: 17607-15. PMID 19406750 DOI: 10.1074/Jbc.M109.002386  1
2009 Appel SJ, Wadas TM, Rosenthal RS, Ovalle F. Latent autoimmune diabetes of adulthood (LADA): an often misdiagnosed type of diabetes mellitus. Journal of the American Academy of Nurse Practitioners. 21: 156-9. PMID 19302691 DOI: 10.1111/J.1745-7599.2009.00399.X  1
2009 Appel SJ, Oster RA, Floyd NA, Ovalle F. Cardiometabolic risk among African American women: a pilot study. The Journal of Cardiovascular Nursing. 24: 140-50. PMID 19242280 DOI: 10.1097/JCN.0b013e318197aa3a  1
2009 Appel S, Barres B, Carlson K, Chernyshev A, Cox G, Fanara P, Gatchel J, Glass J, Johnson E, Johnstone B, Leitner M, Li Y, Lutz C, Ngo H, Perrin S, et al. Alzheimer research forum live discussion: Mice on trial? issues in the design of drug studies Journal of Alzheimer's Disease. 16: 197-205. PMID 19158436 DOI: 10.3233/Jad-2009-0961  1
2009 Appel SH. CD4+ T cells mediate cytotoxicity in neurodegenerative diseases. The Journal of Clinical Investigation. 119: 13-5. PMID 19104142 DOI: 10.1172/Jci38096  1
2009 Appel S, Achilles S, Biskup M. Engineering study of vibrations and dimensioning of the permanent way within the framework of the "Cracow Tram" project | Schwingungstechnische Untersuchungen und Dimensionierung des Oberbaus im Rahmen des Projektes "Tram Krakau" Vdi Berichte. 29-40.  1
2009 Vrettos C, Appel S, Saidel T. Dynamic calculation of a pile-supported paper printing machine | Dynamische Berechnung einer auf Pfählen Gegründeten Papierdruckmaschine Vdi Berichte. 543-554.  1
2008 Jones EJ, Appel SJ. Type 2 diabetes: fueling the surge of cardiovascular disease in women. Nursing For Women's Health. 12: 500-13; quiz 514. PMID 19121055 DOI: 10.1111/j.1751-486X.2008.00384.x  1
2008 Kim HR, Appel S, Vetterkind S, Gangopadhyay SS, Morgan KG. Smooth muscle signalling pathways in health and disease. Journal of Cellular and Molecular Medicine. 12: 2165-80. PMID 19120701 DOI: 10.1111/J.1582-4934.2008.00552.X  1
2008 Appel SL, Lefebvre SL, Houston DM, Holmberg DL, Stone JE, Moore AE, Weese JS. Evaluation of risk factors associated with suture-nidus cystoliths in dogs and cats: 176 cases (1999-2006). Journal of the American Veterinary Medical Association. 233: 1889-95. PMID 19072603 DOI: 10.2460/javma.233.12.1889  1
2008 Sorenson EJ, Windbank AJ, Mandrekar JN, Bamlet WR, Appel SH, Armon C, Barkhaus PE, Bosch P, Boylan K, David WS, Feldman E, Glass J, Gutmann L, Katz J, King W, et al. Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology. 71: 1770-5. PMID 19029516 DOI: 10.1212/01.Wnl.0000335970.78664.36  1
2008 Delaleu N, Jonsson MV, Appel S, Jonsson R. New concepts in the pathogenesis of Sjögren's syndrome. Rheumatic Diseases Clinics of North America. 34: 833-45, vii. PMID 18984407 DOI: 10.1016/j.rdc.2008.08.004  1
2008 Appel SH, Engelhardt JI, Henkel JS, Siklos L, Beers DR, Yen AA, Simpson EP, Luo Y, Carrum G, Heslop HE, Brenner MK, Popat U. Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis. Neurology. 71: 1326-34. PMID 18936424 DOI: 10.1212/01.Wnl.0000327668.43541.22  1
2008 Beers DR, Henkel JS, Zhao W, Wang J, Appel SH. CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proceedings of the National Academy of Sciences of the United States of America. 105: 15558-63. PMID 18809917 DOI: 10.1073/Pnas.0807419105  1
2008 Appel SJ, Giger JN, Davidhizar RE. Opportunity cost: the impact of contextual risk factors on the cardiovascular health of low-income rural southern African-American women. Journal of National Black Nurses' Association : Jnbna. 19: 42-51. PMID 18807778  1
2008 Appel SJ, Downs CA. Understanding acid-base balance. Find out how to interpret values and steady a disturbed equilibrium in an acutely ill patient. Nursing. 38: 9-11. PMID 18797369 DOI: 10.1097/01.NURSE.0000336658.39936.0c  1
2008 Appel SL, Moens NM, Abrams-Ogg AC, Woods JP, Nykamp S, Bienzle D. Multiple myeloma with central nervous system involvement in a cat. Journal of the American Veterinary Medical Association. 233: 743-7. PMID 18764709 DOI: 10.2460/Javma.233.5.743  0.01
2008 Appel SH, Beers DR, Henkel JS, Zhao W. Novel therapeutic targets in neurodegenerative diseases: lessons from amyotrophic lateral sclerosis. Current Neurology and Neuroscience Reports. 8: 353-5. PMID 18713569 DOI: 10.1007/S11910-008-0054-6  1
2008 Giger JN, Appel SJ, Davidhizar R, Davis C. Church and spirituality in the lives of the African American community. Journal of Transcultural Nursing : Official Journal of the Transcultural Nursing Society / Transcultural Nursing Society. 19: 375-83. PMID 18650398 DOI: 10.1177/1043659608322502  1
2008 Villoslada P, Moreno B, Melero I, Pablos JL, Martino G, Uccelli A, Montalban X, Avila J, Rivest S, Acarin L, Appel S, Khoury SJ, McGeer P, Ferrer I, Delgado M, et al. Immunotherapy for neurological diseases. Clinical Immunology (Orlando, Fla.). 128: 294-305. PMID 18534912 DOI: 10.1016/J.Clim.2008.04.003  1
2008 Voustianiouk A, Seidel G, Panchal J, Sivak M, Czaplinski A, Yen A, Appel SH, Lange DJ. ALSFRS and appel ALS scores: discordance with disease progression. Muscle & Nerve. 37: 668-72. PMID 18288708 DOI: 10.1002/Mus.20977  1
2008 Weck MM, Appel S, Werth D, Sinzger C, Bringmann A, Grünebach F, Brossart P. hDectin-1 is involved in uptake and cross-presentation of cellular antigens. Blood. 111: 4264-72. PMID 17698636 DOI: 10.1182/blood-2006-10-051375  1
2007 Appel SJ, Giger JN. The nurse's role in discouraging clinical inertia in diabetes management: optimizing cardiovascular health among African-Americans. Journal of National Black Nurses' Association : Jnbna. 18: vii-viii. PMID 18318325  1
2007 Appel SJ, Floyd NA, Jones EJ. Reducing cardiovascular risk and managing dyslipidemia in women. Nursing For Women's Health. 11: 586-99. PMID 18088296 DOI: 10.1111/j.1751-486X.2007.00245.x  1
2007 Demirel O, Waibler Z, Kalinke U, Grünebach F, Appel S, Brossart P, Hasilik A, Tampé R, Abele R. Identification of a lysosomal peptide transport system induced during dendritic cell development. The Journal of Biological Chemistry. 282: 37836-43. PMID 17977821 DOI: 10.1074/jbc.M708139200  1
2007 Barsheshet A, Marai I, Appel S, Zimlichman E. Acute ST elevation myocardial infarction during intravenous immunoglobulin infusion. Annals of the New York Academy of Sciences. 1110: 315-8. PMID 17911446 DOI: 10.1196/annals.1423.033  0.01
2007 Wheaton MW, Salamone AR, Mosnik DM, McDonald RO, Appel SH, Schmolck HI, Ringholz GM, Schulz PE. Cognitive impairment in familial ALS. Neurology. 69: 1411-7. PMID 17909153 DOI: 10.1212/01.Wnl.0000277422.11236.2C  1
2007 Appel SJ, Bannon JM. Hazardous waist: how body shape puts health at risk. Nursing For Women's Health. 11: 44-53. PMID 17883816 DOI: 10.1111/j.1751-486X.2007.00117.x  1
2007 Miller R, Bradley W, Cudkowicz M, Hubble J, Meininger V, Mitsumoto H, Moore D, Pohlmann H, Sauer D, Silani V, Strong M, Swash M, Vernotica E, Cashman N, Eisen A, ... ... Appel S, et al. Phase II/III randomized trial of TCH346 in patients with ALS Neurology. 69: 776-784. PMID 17709710 DOI: 10.1212/01.Wnl.0000269676.07319.09  1
2007 Dunckley T, Huentelman MJ, Craig DW, Pearson JV, Szelinger S, Joshipura K, Halperin RF, Stamper C, Jensen KR, Letizia D, Hesterlee SE, Pestronk A, Levine T, Bertorini T, Graves MC, ... ... Appel SH, et al. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. The New England Journal of Medicine. 357: 775-88. PMID 17671248 DOI: 10.1056/Nejmoa070174  1
2007 Appel SJ, Wright MA, Ovalle F. Optimizing insulin regimes. The Nurse Practitioner. 32: 18-26; CEU quiz 26-7. PMID 17667762 DOI: 10.1097/01.NPR.0000282797.81819.94  1
2007 Appel S, Brossart P. Development of novel compounds to treat autoimmune and inflammatory diseases and graft versus host reactions. Endocrine, Metabolic & Immune Disorders Drug Targets. 7: 93-7. PMID 17584149 DOI: 10.2174/187153007780832073  1
2007 Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH. Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia. Journal of Neurochemistry. 102: 2008-19. PMID 17555556 DOI: 10.1111/J.1471-4159.2007.04677.X  1
2007 Appel S, Chapman J, Shoenfeld Y. Infection and vaccination in chronic fatigue syndrome: myth or reality? Autoimmunity. 40: 48-53. PMID 17364497 DOI: 10.1080/08916930701197273  1
2007 Downs CA, Appel SJ. Chronic obstructive pulmonary disease: diagnosis and management. Journal of the American Academy of Nurse Practitioners. 19: 126-32. PMID 17341279 DOI: 10.1111/J.1745-7599.2006.00207.X  1
2007 Appel SJ, Wright MA. Teach your patient to administer: inhaled insulin. Nursing. 37: 49-50. PMID 17198163  1
2007 Wright MA, Appel SJ. Inhaled insulin: breathing new life into diabetes therapy. Nursing. 37: 46-8. PMID 17198162  1
2007 Koyama S, Brodie MS, Appel SB. Ethanol inhibition of m-current and ethanol-induced direct excitation of ventral tegmental area dopamine neurons. Journal of Neurophysiology. 97: 1977-85. PMID 16956995 DOI: 10.1152/Jn.00270.2006  1
2007 Czaplinski A, Yen AA, Simpson EP, Appel SH. In reply [5] Archives of Neurology. 64: 459.  1
2006 Appel SJ, Moore TM, Giger JN. An overview and update on the metabolic syndrome: implications for identifying cardiometabolic risk among African-American women. Journal of National Black Nurses' Association : Jnbna. 17: 47-62. PMID 17410759  1
2006 Jones DE, Weaver MT, Grimley D, Appel SJ, Ard J. Health belief model perceptions, knowledge of heart disease, and its risk factors in educated African-American women: an exploration of the relationships of socioeconomic status and age. Journal of National Black Nurses' Association : Jnbna. 17: 13-23. PMID 17410755  1
2006 Czaplinski A, Haverkamp LJ, Yen AA, Simpson EP, Lai EC, Appel SH. The value of database controls in pilot or futility studies in ALS. Neurology. 67: 1827-32. PMID 17130417 DOI: 10.1212/01.Wnl.0000244415.48221.81  1
2006 Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 16021-6. PMID 17043238 DOI: 10.1073/Pnas.0607423103  1
2006 Zhao W, Xie W, Xiao Q, Beers DR, Appel SH. Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia. Journal of Neurochemistry. 99: 1176-87. PMID 17018025 DOI: 10.1111/J.1471-4159.2006.04172.X  1
2006 Appel SJ, Floyd NA, Giger JN, Weaver MT, Luo H, Hannah T, Ovalle F. African-American women, metabolic syndrome, and national cholesterol education program criteria: a pilot study. Journal of National Black Nurses' Association : Jnbna. 17: 9-16. PMID 17004421  1
2006 Czaplinski A, Yen AA, Simpson EP, Appel SH. Predictability of disease progression in amyotrophic lateral sclerosis. Muscle & Nerve. 34: 702-8. PMID 16967489 DOI: 10.1002/Mus.20658  1
2006 Vogelsang P, Jonsson MV, Dalvin ST, Appel S. Role of dendritic cells in Sjögren's syndrome. Scandinavian Journal of Immunology. 64: 219-26. PMID 16918690 DOI: 10.1111/j.1365-3083.2006.01811.x  1
2006 Czaplinski A, Yen AA, Simpson EP, Appel SH. Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing? Archives of Neurology. 63: 1139-43. PMID 16908741 DOI: 10.1001/Archneur.63.8.1139  1
2006 Rincon M, Broadwater G, Harris L, Crocker A, Weaver D, Dressler L, Berry D, Sutton L, Michaelson R, Messino M, Kirshner J, Fleming G, Winer E, Hudis C, Appel S, et al. Interleukin-6, multidrug resistance protein-1 expression and response to paclitaxel in women with metastatic breast cancer: results of cancer and leukemia group B trial 159806. Breast Cancer Research and Treatment. 100: 301-8. PMID 16773437 DOI: 10.1007/S10549-006-9251-7  0.01
2006 Czaplinski A, Yen AA, Appel SH. Amyotrophic lateral sclerosis: early predictors of prolonged survival. Journal of Neurology. 253: 1428-36. PMID 16773270 DOI: 10.1007/S00415-006-0226-8  1
2006 Appel SB, Wise L, McDaid J, Koyama S, McElvain MA, Brodie MS. The effects of long chain-length n-alcohols on the firing frequency of dopaminergic neurons of the ventral tegmental area. The Journal of Pharmacology and Experimental Therapeutics. 318: 1137-45. PMID 16740620 DOI: 10.1124/Jpet.106.105148  1
2006 Appel SJ. Metabolic syndrome: fact or fiction. Journal of the American Academy of Nurse Practitioners. 18: 255-7. PMID 16719843 DOI: 10.1111/J.1745-7599.2006.00127.X  1
2006 Koyama S, Appel SB. A-type K+ current of dopamine and GABA neurons in the ventral tegmental area. Journal of Neurophysiology. 96: 544-54. PMID 16611837 DOI: 10.1152/jn.01318.2005  1
2006 Evans AH, Pavese N, Lawrence AD, Tai YF, Appel S, Doder M, Brooks DJ, Lees AJ, Piccini P. Compulsive drug use linked to sensitized ventral striatal dopamine transmission. Annals of Neurology. 59: 852-8. PMID 16557571 DOI: 10.1002/Ana.20822  1
2006 Appel SL, Maggs DJ, Hollingsworth SR, Kass PH. Evaluation of client perceptions concerning outcome of cataract surgery in dogs. Journal of the American Veterinary Medical Association. 228: 870-5. PMID 16536695 DOI: 10.2460/javma.228.6.870  1
2006 Goldknopf IL, Sheta EA, Bryson J, Folsom B, Wilson C, Duty J, Yen AA, Appel SH. Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson's disease. Biochemical and Biophysical Research Communications. 342: 1034-9. PMID 16516157 DOI: 10.1016/J.Bbrc.2006.02.051  1
2006 Czaplinski A, Yen AA, Appel SH. Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population. Journal of Neurology, Neurosurgery, and Psychiatry. 77: 390-2. PMID 16484652 DOI: 10.1136/Jnnp.2005.072660  1
2006 Appel SH. Is ALS a systemic disorder? Evidence from muscle mitochondria. Experimental Neurology. 198: 1-3. PMID 16458887 DOI: 10.1016/J.Expneurol.2005.12.025  1
2006 Sheta EA, Appel SH, Goldknopf IL. 2D gel blood serum biomarkers reveal differential clinical proteomics of the neurodegenerative diseases. Expert Review of Proteomics. 3: 45-62. PMID 16445350 DOI: 10.1586/14789450.3.1.45  1
2006 Koyama S, Appel SB. Characterization of M-current in ventral tegmental area dopamine neurons. Journal of Neurophysiology. 96: 535-43. PMID 16394077 DOI: 10.1152/jn.00574.2005  1
2006 Appel S, Bringmann A, Grünebach F, Weck MM, Bauer J, Brossart P. Epithelial-specific transcription factor ESE-3 is involved in the development of monocyte-derived DCs. Blood. 107: 3265-70. PMID 16380452 DOI: 10.1182/blood-2005-06-2480  1
2006 Henkel JS, Beers DR, Siklós L, Appel SH. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Molecular and Cellular Neurosciences. 31: 427-37. PMID 16337133 DOI: 10.1016/J.Mcn.2005.10.016  1
2006 Heine A, Grünebach F, Holderried T, Appel S, Weck MM, Dörfel D, Sinzger C, Brossart P. Transfection of dendritic cells with in vitro-transcribed CMV RNA induces polyclonal CD8+- and CD4+-mediated CMV-specific T cell responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 280-8. PMID 16219490 DOI: 10.1016/j.ymthe.2005.08.019  1
2006 Czaplinski A, Appel SH. Amyotrophic lateral sclerosis: Can we predict the course of disease? Schweizer Archiv Fur Neurologie Und Psychiatrie. 157: 317-322.  1
2005 Appel SJ. Sizing up patients for metabolic syndrome. Nursing. 35: 20-1. PMID 16331195  1
2005 Evans AH, Lawrence AD, Potts J, Appel S, Lees AJ. Factors influencing susceptibility to compulsive dopaminergic drug use in Parkinson disease. Neurology. 65: 1570-4. PMID 16301483 DOI: 10.1212/01.Wnl.0000184487.72289.F0  1
2005 Appel SJ, Harrell JS, Davenport ML. Central obesity, the metabolic syndrome, and plasminogen activator inhibitor-1 in young adults. Journal of the American Academy of Nurse Practitioners. 17: 535-41. PMID 16293162 DOI: 10.1111/J.1745-7599.2005.00083.X  1
2005 Yoshor D, Klugh A, Appel SH, Haverkamp LJ. Incidence and characteristics of spinal decompression surgery after the onset of symptoms of amyotrophic lateral sclerosis. Neurosurgery. 57: 984-9; discussion 98. PMID 16284567 DOI: 10.1227/01.Neu.0000180028.64385.D3  1
2005 Appel SJ, Floyd NA, Giger JN, Weaver MT, Luo H, Hannah T, Ovalle F. African American women, metabolic syndrome, and national cholesterol education program criteria: a pilot study. Nursing Research. 54: 339-46. PMID 16224320 DOI: 10.1097/00006199-200509000-00008  1
2005 Armeanu S, Bitzer M, Smirnow I, Bossow S, Appel S, Ungerechts G, Bernloehr C, Neubert WJ, Lauer UM, Brossart P. Severe impairment of dendritic cell allostimulatory activity by Sendai virus vectors is overcome by matrix protein gene deletion. Journal of Immunology (Baltimore, Md. : 1950). 175: 4971-80. PMID 16210599  1
2005 Mitsumoto H, Bromberg M, Johnston W, Tandan R, Byock I, Lyon M, Miller RG, Appel SH, Benditt J, Bernat JL, Borasio GD, Carver AC, Clawson L, Del Bene ML, Kasarskis EJ, et al. Promoting excellence in end-of-life care in ALS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 6: 145-54. PMID 16183556 DOI: 10.1080/14660820510028647  1
2005 Appel SJ, Giger JN, Davidhizar RE. Opportunity cost: the impact of contextual risk factors on the cardiovascular health of low-income rural southern African American women. The Journal of Cardiovascular Nursing. 20: 315-24. PMID 16141776 DOI: 10.1097/00005082-200509000-00005  1
2005 Appel S, Balabanov S, Brümmendorf TH, Brossart P. Effects of imatinib on normal hematopoiesis and immune activation. Stem Cells (Dayton, Ohio). 23: 1082-8. PMID 16140870 DOI: 10.1634/stemcells.2005-0069  1
2005 Simpson EP, Appel SH. "Individual and health-related quality of life assessment in amyotrophic lateral sclerosis patients and their caregivers" by Lo Coco G, Lo Coco D, Cicero V, Oliveri A, Lo Verso G, Piccolo F, La Bella V. Journal of the Neurological Sciences. 238: 1-2. PMID 16125725 DOI: 10.1016/J.Jns.2005.06.010  1
2005 Ringholz GM, Appel SH, Bradshaw M, Cooke NA, Mosnik DM, Schulz PE. Prevalence and patterns of cognitive impairment in sporadic ALS. Neurology. 65: 586-90. PMID 16116120 DOI: 10.1212/01.Wnl.0000172911.39167.B6  1
2005 Appel S, Mirakaj V, Bringmann A, Weck MM, Grünebach F, Brossart P. PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways. Blood. 106: 3888-94. PMID 16105976 DOI: 10.1182/blood-2004-12-4709  1
2005 Appel SJ. Calculating insulin resistance in the primary care setting: why should we worry about insulin levels in euglycemic patients? Journal of the American Academy of Nurse Practitioners. 17: 331-6. PMID 16045594 DOI: 10.1111/J.1745-7599.2005.0052.X  1
2005 Das A, Sribnick EA, Wingrave JM, Del Re AM, Woodward JJ, Appel SH, Banik NL, Ray SK. Calpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotection. Journal of Neuroscience Research. 81: 551-62. PMID 15968645 DOI: 10.1002/Jnr.20581  1
2005 Balabanov S, Appel S, Kanz L, Brossart P, Brümmendorf TH. Effect of tyrosine kinase inhibition using imatinib on normal lymphohematopoietic cells. Annals of the New York Academy of Sciences. 1044: 168-77. PMID 15958710 DOI: 10.1196/annals.1349.022  1
2005 Vigh L, Smith RG, Soós J, Engelhardt JI, Appel SH, Siklós L. Sublethal dose of 4-hydroxynonenal reduces intracellular calcium in surviving motor neurons in vivo. Acta Neuropathologica. 109: 567-75. PMID 15933871 DOI: 10.1007/S00401-004-0977-1  1
2005 Garfield BE, Krahl T, Appel S, Cooper SM, Rincón M. Regulation of p38 MAP kinase in CD4+ lymphocytes by infliximab therapy in patients with rheumatoid arthritis. Clinical Immunology (Orlando, Fla.). 116: 101-7. PMID 15914087 DOI: 10.1016/j.clim.2005.04.010  1
2005 Grünebach F, Kayser K, Weck MM, Müller MR, Appel S, Brossart P. Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes. Cancer Gene Therapy. 12: 749-56. PMID 15877082 DOI: 10.1038/sj.cgt.7700842  1
2005 Vetterkind S, Illenberger S, Kubicek J, Boosen M, Appel S, Naim HY, Scheidtmann KH, Preuss U. Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis. Experimental Cell Research. 305: 392-408. PMID 15817164 DOI: 10.1016/j.yexcr.2005.01.012  1
2005 Appel S, Rupf A, Weck MM, Schoor O, Brümmendorf TH, Weinschenk T, Grünebach F, Brossart P. Effects of imatinib on monocyte-derived dendritic cells are mediated by inhibition of nuclear factor-kappaB and Akt signaling pathways. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1928-40. PMID 15756019 DOI: 10.1158/1078-0432.CCR-04-1713  1
2005 Dörfel D, Appel S, Grünebach F, Weck MM, Müller MR, Heine A, Brossart P. Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA. Blood. 105: 3199-205. PMID 15618468 DOI: 10.1182/blood-2004-09-3556  1
2005 Siklós L, Appel SH. Calcium binding proteins in selective vulnerability of motor neurons Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 65-79. DOI: 10.1017/CBO9780511544873.007  1
2004 Appel SJ. Metabolic syndrome: broadening the understanding of African-American women's risk for cardiovascular disease. Journal of National Black Nurses' Association : Jnbna. 15: vii-ix. PMID 15712813  1
2004 Appel SH. Euthanasia and physician-assisted suicide in ALS: a commentary. The American Journal of Hospice & Palliative Care. 21: 405-6. PMID 15612229  1
2004 Yen A, Simpson E, Haverkamp L, Appel S. AALSS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 5: 94-8. PMID 15512884 DOI: 10.1080/17434470410019708  1
2004 Yen A, Simpson E, Haverkamp L, Appel S. Design using historical controls. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 5: 61-3. PMID 15512876 DOI: 10.1080/17434470410019807  1
2004 Brooks BR, Thisted RA, Appel SH, Bradley WG, Olney RK, Berg JE, Pope LE, Smith RA. Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology. 63: 1364-70. PMID 15505150 DOI: 10.1212/01.Wnl.0000142042.50528.2F  1
2004 Appel SJ, Giger JN, Floyd NA. Dysmetabolic syndrome: reducing cardiovascular risk. The Nurse Practitioner. 29: 18-35; quiz 35-7. PMID 15489668 DOI: 10.1097/00006205-200410000-00004  1
2004 Appel SJ, Jones ED, Kennedy-Malone L. Central obesity and the metabolic syndrome: implications for primary care providers. Journal of the American Academy of Nurse Practitioners. 16: 335-42. PMID 15455706 DOI: 10.1111/J.1745-7599.2004.Tb00456.X  1
2004 Zhao W, Xie W, Le W, Beers DR, He Y, Henkel JS, Simpson EP, Yen AA, Xiao Q, Appel SH. Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. Journal of Neuropathology and Experimental Neurology. 63: 964-77. PMID 15453095 DOI: 10.1093/Jnen/63.9.964  1
2004 Koh SH, Kwon H, Kim KS, Kim J, Kim MH, Yu HJ, Kim M, Lee KW, Do BR, Jung HK, Yang KW, Appel SH, Kim SH. Epigallocatechin gallate prevents oxidative-stress-induced death of mutant Cu/Zn-superoxide dismutase (G93A) motoneuron cells by alteration of cell survival and death signals. Toxicology. 202: 213-25. PMID 15337584 DOI: 10.1016/J.Tox.2004.05.008  1
2004 Carter-Edwards L, Skelly AH, Cagle CS, Appel SJ. "They care but don't understand": family support of African American women with type 2 diabetes. The Diabetes Educator. 30: 493-501. PMID 15208847 DOI: 10.1177/014572170403000321  1
2004 Trail M, Nelson N, Van JN, Appel SH, Lai EC. Major stressors facing patients with amyotrophic lateral sclerosis (ALS): a survey to identify their concerns and to compare with those of their caregivers. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 5: 40-5. PMID 15204023 DOI: 10.1080/14660820310016075  1
2004 Schag K, Schmidt SM, Müller MR, Weinschenk T, Appel S, Weck MM, Grünebach F, Stevanovic S, Rammensee HG, Brossart P. Identification of C-met oncogene as a broadly expressed tumor-associated antigen recognized by cytotoxic T-lymphocytes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3658-66. PMID 15173072 DOI: 10.1158/1078-0432.CCR-03-0640  1
2004 Simpson EP, Henry YK, Henkel JS, Smith RG, Appel SH. Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden. Neurology. 62: 1758-65. PMID 15159474 DOI: 10.1212/Wnl.62.10.1758  1
2004 Francis MK, Appel S, Meyer C, Balin SJ, Balin AK, Cristofalo VJ. Loss of EPC-1/PEDF expression during skin aging in vivo. The Journal of Investigative Dermatology. 122: 1096-105. PMID 15140209 DOI: 10.1111/j.0022-202X.2004.22510.x  0.01
2004 Yen AA, Simpson EP, Henkel JS, Beers DR, Appel SH. HFE mutations are not strongly associated with sporadic ALS. Neurology. 62: 1611-2. PMID 15136693 DOI: 10.1212/01.Wnl.0000123114.04644.Cc  1
2004 Evans AH, Katzenschlager R, Paviour D, O'Sullivan JD, Appel S, Lawrence AD, Lees AJ. Punding in Parkinson's disease: its relation to the dopamine dysregulation syndrome. Movement Disorders : Official Journal of the Movement Disorder Society. 19: 397-405. PMID 15077237 DOI: 10.1002/mds.20045  1
2004 Le W, Appel SH. Mutant genes responsible for Parkinson's disease. Current Opinion in Pharmacology. 4: 79-84. PMID 15018843 DOI: 10.1016/J.Coph.2003.09.005  1
2004 Schmidt SM, Schag K, Müller MR, Weinschenk T, Appel S, Schoor O, Weck MM, Grünebach F, Kanz L, Stevanovic S, Rammensee HG, Brossart P. Induction of adipophilin-specific cytotoxic T lymphocytes using a novel HLA-A2-binding peptide that mediates tumor cell lysis. Cancer Research. 64: 1164-70. PMID 14871853 DOI: 10.1158/0008-5472.CAN-03-2538  1
2004 Henkel JS, Engelhardt JI, Siklós L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Annals of Neurology. 55: 221-35. PMID 14755726 DOI: 10.1002/Ana.10805  1
2004 Kim SH, Engelhardt JI, Henkel JS, Siklós L, Soós J, Goodman C, Appel SH. Widespread increased expression of the DNA repair enzyme PARP in brain in ALS. Neurology. 62: 319-22. PMID 14745081 DOI: 10.1212/01.Wnl.0000103291.04985.Dc  1
2004 Appel S, Boehmler AM, Grünebach F, Müller MR, Rupf A, Weck MM, Hartmann U, Reichardt VL, Kanz L, Brümmendorf TH, Brossart P. Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells. Blood. 103: 538-44. PMID 14504105 DOI: 10.1182/blood-2003-03-0975  1
2004 Yen A, Simpson E, Haverkamp L, Appel S. AALSS Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders. 5: 94-98. DOI: 10.1080/17434470410019708-65  0.01
2003 Simpson EP, Yen AA, Appel SH. Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis. Current Opinion in Rheumatology. 15: 730-6. PMID 14569202 DOI: 10.1097/00002281-200311000-00008  1
2003 Sengun IS, Appel SH. Serum anti-Fas antibody levels in amyotrophic lateral sclerosis. Journal of Neuroimmunology. 142: 137-40. PMID 14512172 DOI: 10.1016/S0165-5728(03)00263-7  1
2003 Nelson ND, Trail M, Van JN, Appel SH, Lai EC. Quality of life in patients with amyotrophic lateral sclerosis: perceptions, coping resources, and illness characteristics. Journal of Palliative Medicine. 6: 417-24. PMID 14509487 DOI: 10.1089/109662103322144736  1
2003 He Y, Imam SZ, Dong Z, Jankovic J, Ali SF, Appel SH, Le W. Role of nitric oxide in rotenone-induced nigro-striatal injury. Journal of Neurochemistry. 86: 1338-45. PMID 12950443 DOI: 10.1046/J.1471-4159.2003.01938.X  1
2003 Cudkowicz ME, Shefner JM, Schoenfeld DA, Brown RH, Johnson H, Qureshi M, Jacobs M, Rothstein JD, Appel SH, Pascuzzi RM, Heiman-Patterson TD, Donofrio PD, David WS, Russell JA, Tandan R, et al. A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis. Neurology. 61: 456-64. PMID 12939417 DOI: 10.1212/Wnl.61.4.456  1
2003 Liu Z, Bunney EB, Appel SB, Brodie MS. Serotonin reduces the hyperpolarization-activated current (Ih) in ventral tegmental area dopamine neurons: involvement of 5-HT2 receptors and protein kinase C. Journal of Neurophysiology. 90: 3201-12. PMID 12890794 DOI: 10.1152/Jn.00281.2003  1
2003 Appel SB, Liu Z, McElvain MA, Brodie MS. Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine. The Journal of Pharmacology and Experimental Therapeutics. 306: 437-46. PMID 12721326 DOI: 10.1124/Jpet.103.050963  1
2003 Trail M, Nelson ND, Van JN, Appel SH, Lai EC. A study comparing patients with amyotrophic lateral sclerosis and their caregivers on measures of quality of life, depression, and their attitudes toward treatment options. Journal of the Neurological Sciences. 209: 79-85. PMID 12686407 DOI: 10.1016/S0022-510X(03)00003-0  1
2003 Schmidt SM, Schag K, Müller MR, Weck MM, Appel S, Kanz L, Grünebach F, Brossart P. Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells. Blood. 102: 571-6. PMID 12576330 DOI: 10.1182/blood-2002-08-2554  1
2003 Kim SH, Henkel JS, Beers DR, Sengun IS, Simpson EP, Goodman JC, Engelhardt JI, Siklós L, Appel SH. PARP expression is increased in astrocytes but decreased in motor neurons in the spinal cord of sporadic ALS patients. Journal of Neuropathology and Experimental Neurology. 62: 88-103. PMID 12528821 DOI: 10.1093/Jnen/62.1.88  1
2003 Le WD, Xu P, Jankovic J, Jiang H, Appel SH, Smith RG, Vassilatis DK. Mutations in NR4A2 associated with familial Parkinson disease. Nature Genetics. 33: 85-9. PMID 12496759 DOI: 10.1038/Ng1066  1
2003 Borasio GD, Appel SH. Upper and Lower Motor Neuron Disorders Neurological Disorders: Course and Treatment: Second Edition. 1165-1176. DOI: 10.1016/B978-012125831-3/50276-8  1
2002 Cagle CS, Appel S, Skelly AH, Carter-Edwards L. Mid-life African-American women with type 2 diabetes: influence on work and the multicaregiver role. Ethnicity & Disease. 12: 555-66. PMID 12477143  1
2002 He Y, Le WD, Appel SH. Role of Fcgamma receptors in nigral cell injury induced by Parkinson disease immunoglobulin injection into mouse substantia nigra. Experimental Neurology. 176: 322-7. PMID 12359173 DOI: 10.1006/Exnr.2002.7946  1
2002 Stöwe K, Appel S. Polymorphic forms of rubidium telluride Rb2Te. Angewandte Chemie (International Ed. in English). 41: 2725-30. PMID 12203467 DOI: 10.1002/1521-3773(20020802)41:15<2725::AID-ANIE2725>3.0.CO;2-G  1
2002 Mohamed HA, Mosier DR, Zou LL, Siklós L, Alexianu ME, Engelhardt JI, Beers DR, Le WD, Appel SH. Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons. Journal of Neuroscience Research. 69: 110-6. PMID 12111822 DOI: 10.1002/Jnr.10271  1
2002 Appel SJ, Harrell JS, Deng S. Racial and socioeconomic differences in risk factors for cardiovascular disease among Southern rural women. Nursing Research. 51: 140-7. PMID 12063412 DOI: 10.1097/00006199-200205000-00002  1
2002 Simpson EP, Mosier D, Appel SH. Mechanisms of disease pathogenesis in amyotrophic lateral sclerosis. A central role for calcium. Advances in Neurology. 88: 1-19. PMID 11908220  1
2002 Appel S, Filter M, Reis A, Hennies HC, Bergheim A, Ogilvie E, Arndt S, Simmons A, Lovett M, Hide W, Ramsay M, Reichwald K, Zimmermann W, Rosenthal A. Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759. European Journal of Human Genetics : Ejhg. 10: 17-25. PMID 11896452 DOI: 10.1038/Sj.Ejhg.5200750  1
2001 Appel SH, Simpson EP. Activated microglia: the silent executioner in neurodegenerative disease? Current Neurology and Neuroscience Reports. 1: 303-5. PMID 11898534 DOI: 10.1007/S11910-001-0081-Z  1
2001 Beers DR, Ho BK, Siklós L, Alexianu ME, Mosier DR, Mohamed AH, Otsuka Y, Kozovska ME, McAlhany RE, Smith RG, Appel SH. Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis. Journal of Neurochemistry. 79: 499-509. PMID 11701753 DOI: 10.1046/J.1471-4159.2001.00582.X  1
2001 Le W, Rowe D, Xie W, Ortiz I, He Y, Appel SH. Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8447-55. PMID 11606633  1
2001 Alexianu ME, Kozovska M, Appel SH. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology. 57: 1282-9. PMID 11591849 DOI: 10.1212/Wnl.57.7.1282  1
2001 Eisenberg DM, Kessler RC, Van Rompay MI, Kaptchuk TJ, Wilkey SA, Appel S, Davis RB. Perceptions about complementary therapies relative to conventional therapies among adults who use both: results from a national survey. Annals of Internal Medicine. 135: 344-51. PMID 11529698 DOI: 10.7326/0003-4819-135-5-200109040-00011  1
2001 He Y, Appel S, Le W. Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Research. 909: 187-93. PMID 11478935 DOI: 10.1016/S0006-8993(01)02681-6  1
2001 Appel S, Reichwald K, Zimmermann W, Reis A, Rosenthal A, Hennies HC. Identification and localization of a new human myotubularin-related protein gene, mtmr8, on 8p22-p23. Genomics. 75: 6-8. PMID 11472061 DOI: 10.1006/geno.2001.6591  1
2001 Appel SH, Beers D, Siklos L, Engelhardt JI, Mosier DR. Calcium: the Darth Vader of ALS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 2: S47-54. PMID 11465925 DOI: 10.1080/146608201300079418  1
2001 Seidl J, Rauch J, Krieg RC, Appel S, Baumgartner R, Knuechel R. Optimization of differential photodynamic effectiveness between normal and tumor urothelial cells using 5-aminolevulinic acid-induced protoporphyrin IX as sensitizer. International Journal of Cancer. Journal International Du Cancer. 92: 671-7. PMID 11340570 DOI: 10.1002/1097-0215(20010601)92:5<671::AID-IJC1240>3.0.CO;2-P  0.01
2001 Bodamer OA, Rosenblatt DS, Appel SH, Beaudet AL. Adult-onset combined methylmalonic aciduria and homocystinuria (cblC). Neurology. 56: 1113. PMID 11320193 DOI: 10.1212/Wnl.56.8.1113  1
2001 Bunney EB, Appel SB, Brodie MS. Electrophysiological effects of cocaethylene, cocaine, and ethanol on dopaminergic neurons of the ventral tegmental area. The Journal of Pharmacology and Experimental Therapeutics. 297: 696-703. PMID 11303060  1
2001 Trail M, Nelson N, Van JN, Appel SH, Lai EC. Wheelchair use by patients with amyotrophic lateral sclerosis: a survey of user characteristics and selection preferences. Archives of Physical Medicine and Rehabilitation. 82: 98-102. PMID 11239293 DOI: 10.1053/Apmr.2001.18062  1
2000 Smith RG, Appel SH. Immunosuppression and anti-inflammatory agents in ALS. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 33-42; discussion 42. PMID 11466958 DOI: 10.1080/14660820050515692-1  1
2000 Appel SH, Beers D, Smith RG, Wilson JE. Altered calcium homeostasis in ALS as a target for therapy. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 1: 27-32. PMID 11466956  1
2000 Le WD, Jankovic J, Xie W, Appel SH. Antioxidant property of pramipexole independent of dopamine receptor activation in neuroprotection. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 1165-73. PMID 11129106 DOI: 10.1007/S007020070030  1
2000 Brodie MS, Appel SB. Dopaminergic neurons in the ventral tegmental area of C57BL/6J and DBA/2J mice differ in sensitivity to ethanol excitation. Alcoholism, Clinical and Experimental Research. 24: 1120-4. PMID 10924018 DOI: 10.1111/J.1530-0277.2000.Tb04658.X  1
2000 Engelhardt JI, Le WD, Siklós L, Obál I, Boda K, Appel SH. Stereotaxic injection of IgG from patients with Alzheimer disease initiates injury of cholinergic neurons of the basal forebrain. Archives of Neurology. 57: 681-6. PMID 10815134 DOI: 10.1001/Archneur.57.5.681  1
2000 Siklós L, Engelhardt JI, Reaume AG, Scott RW, Adalbert R, Obál I, Appel SH. Altered calcium homeostasis in spinal motoneurons but not in oculomotor neurons of SOD-1 knockout mice. Acta Neuropathologica. 99: 517-24. PMID 10805095 DOI: 10.1007/S004010051154  1
2000 Bunney EB, Appel SB, Brodie MS. Cocaine potentiates ethanol-induced excitation of dopaminergic reward neurons in the ventral tegmental area. The Journal of Pharmacology and Experimental Therapeutics. 293: 383-9. PMID 10773006  1
2000 Alexianu ME, Manole E, Engelhardt JI, Appel SH. Ultrastructural evidence of calcium involvement in experimental autoimmune gray matter disease. Journal of Neuroscience Research. 60: 98-105. PMID 10723072 DOI: 10.1002/(Sici)1097-4547(20000401)60:1<98::Aid-Jnr10>3.0.Co;2-B  1
2000 Zou L, Xu J, Jankovic J, He Y, Appel SH, Le W. Pramipexole inhibits lipid peroxidation and reduces injury in the substantia nigra induced by the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice. Neuroscience Letters. 281: 167-70. PMID 10704769 DOI: 10.1016/S0304-3940(00)00853-3  1
2000 Mosier DR, Siklós L, Appel SH. Resistance of extraocular motoneuron terminals to effects of amyotrophic lateral sclerosis sera. Neurology. 54: 252-5. PMID 10636164 DOI: 10.1212/Wnl.54.1.252  1
2000 Ojika K, Mitake S, Tohdoh N, Appel SH, Otsuka Y, Katada E, Matsukawa N. Hippocampal cholinergic neurostimulating peptides (HCNP). Progress in Neurobiology. 60: 37-83. PMID 10622376 DOI: 10.1016/S0301-0082(99)00021-0  1
1999 Brodie MS, Pesold C, Appel SB. Ethanol directly excites dopaminergic ventral tegmental area reward neurons. Alcoholism, Clinical and Experimental Research. 23: 1848-52. PMID 10591603 DOI: 10.1111/J.1530-0277.1999.Tb04082.X  1
1999 Siklós L, Engelhardt JI, Adalbert R, Appel SH. Calcium-containing endosomes at oculomotor terminals in animal models of ALS. Neuroreport. 10: 2539-45. PMID 10574366 DOI: 10.1097/00001756-199908200-00019  1
1999 Le W, Conneely OM, He Y, Jankovic J, Appel SH. Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury. Journal of Neurochemistry. 73: 2218-21. PMID 10537083  1
1999 Panzara MA, Gussoni E, Begovich AB, Murray RS, Zang YQ, Appel SH, Steinman L, Zhang J. T cell receptor BV gene rearrangements in the spinal cords and cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Neurobiology of Disease. 6: 392-405. PMID 10527806 DOI: 10.1006/Nbdi.1999.0252  0.01
1999 Le W, Conneely OM, Zou L, He Y, Saucedo-Cardenas O, Jankovic J, Mosier DR, Appel SH. Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice. Experimental Neurology. 159: 451-8. PMID 10506516 DOI: 10.1006/Exnr.1999.7191  1
1999 Baskin DS, Browning JL, Pirozzolo FJ, Korporaal S, Baskin JA, Appel SH. Brain choline acetyltransferase and mental function in Alzheimer disease. Archives of Neurology. 56: 1121-3. PMID 10488813 DOI: 10.1001/Archneur.56.9.1121  1
1999 Brodie MS, McElvain MA, Bunney EB, Appel SB. Pharmacological reduction of small conductance calcium-activated potassium current (SK) potentiates the excitatory effect of ethanol on ventral tegmental area dopamine neurons. The Journal of Pharmacology and Experimental Therapeutics. 290: 325-33. PMID 10381795  1
1999 Le WD, Xie WJ, Appel SH. Protective role of heme oxygenase-1 in oxidative stress-induced neuronal injury. Journal of Neuroscience Research. 56: 652-8. PMID 10374820 DOI: 10.1002/(Sici)1097-4547(19990615)56:6<652::Aid-Jnr11>3.0.Co;2-5  1
1999 Zou L, Jankovic J, Rowe DB, Xie W, Appel SH, Le W. Neuroprotection by pramipexole against dopamine- and levodopa-induced cytotoxicity. Life Sciences. 64: 1275-85. PMID 10227583 DOI: 10.1016/S0024-3205(99)00062-4  1
1999 Hogikyan ND, Appel S, Guinn LW, Haxer MJ. Vocal fold nodules in adult singers: regional opinions about etiologic factors, career impact, and treatment. A survey of otolaryngologists, speech pathologists, and teachers of singing. Journal of Voice : Official Journal of the Voice Foundation. 13: 128-42. PMID 10223681 DOI: 10.1016/S0892-1997(99)80067-8  0.01
1999 Lee AG, Galetta SL, Lepore FE, Appel SH. Optic atrophy and chronic acquired polyneuropathy. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 19: 67-9. PMID 10098553  0.01
1999 Le WD, Rowe DB, Jankovic J, Xie W, Appel SH. Effects of cerebrospinal fluid from patients with Parkinson disease on dopaminergic cells. Archives of Neurology. 56: 194-200. PMID 10025424 DOI: 10.1001/Archneur.56.2.194  1
1998 Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Van Rompay M, Kessler RC. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. Jama. 280: 1569-75. PMID 9820257 DOI: 10.1097/00006254-199906000-00011  1
1998 Pedersen WA, Fu W, Keller JN, Markesbery WR, Appel S, Smith RG, Kasarskis E, Mattson MP. Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients. Annals of Neurology. 44: 819-24. PMID 9818940 DOI: 10.1002/Ana.410440518  1
1998 Smith RG, Henry YK, Mattson MP, Appel SH. Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis. Annals of Neurology. 44: 696-9. PMID 9778272 DOI: 10.1002/Ana.410440419  1
1998 Giorgetti M, Javaid JI, Davis JM, Costa E, Guidotti A, Appel SB, Brodie MS. Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability. The Journal of Pharmacology and Experimental Therapeutics. 287: 58-66. PMID 9765322  1
1998 Rowe DB, Le W, Smith RG, Appel SH. Antibodies from patients with Parkinson's disease react with protein modified by dopamine oxidation. Journal of Neuroscience Research. 53: 551-8. PMID 9726426 DOI: 10.1002/(Sici)1097-4547(19980901)53:5<551::Aid-Jnr5>3.0.Co;2-8  1
1998 Chen S, Le WD, Xie WJ, Alexianu ME, Engelhardt JI, Siklós L, Appel SH. Experimental destruction of substantia nigra initiated by Parkinson disease immunoglobulins. Archives of Neurology. 55: 1075-80. PMID 9708957 DOI: 10.1001/Archneur.55.8.1075  1
1998 Siklós L, Engelhardt JI, Alexianu ME, Gurney ME, Siddique T, Appel SH. Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice. Journal of Neuropathology and Experimental Neurology. 57: 571-87. PMID 9630237 DOI: 10.1097/00005072-199806000-00005  1
1998 Barry KL, Fleming MF, Manwell LB, Copeland LA, Appel S. Prevalence of and factors associated with current and lifetime depression in older adult primary care patients. Family Medicine. 30: 366-71. PMID 9597536  1
1998 Colom LV, Diaz ME, Beers DR, Neely A, Xie WJ, Appel SH. Role of potassium channels in amyloid-induced cell death. Journal of Neurochemistry. 70: 1925-34. PMID 9572276 DOI: 10.1046/J.1471-4159.1998.70051925.X  1
1998 Brodie MS, Appel SB. The effects of ethanol on dopaminergic neurons of the ventral tegmental area studied with intracellular recording in brain slices. Alcoholism, Clinical and Experimental Research. 22: 236-44. PMID 9514313 DOI: 10.1111/J.1530-0277.1998.Tb03644.X  1
1998 Alexianu ME, Robbins E, Carswell S, Appel SH. 1Alpha, 25 dihydroxyvitamin D3-dependent up-regulation of calcium-binding proteins in motoneuron cells. Journal of Neuroscience Research. 51: 58-66. PMID 9452309 DOI: 10.1002/(Sici)1097-4547(19980101)51:1<58::Aid-Jnr6>3.0.Co;2-K  1
1998 Lange DJ, Murphy PL, Diamond B, Appel V, Lai EC, Younger DS, Appel SH. Selegiline is ineffective in a collaborative double-blind, placebo-controlled trial for treatment of amyotrophic lateral sclerosis. Archives of Neurology. 55: 93-6. PMID 9443715 DOI: 10.1001/Archneur.55.1.93  1
1997 La Bella V, Ho BK, Appel SH. The differential in vitro stimulation of 3',5'-cyclic nucleotide phosphodiesterase by calcium binding proteins. Biochemistry and Molecular Biology International. 43: 1195-205. PMID 9442916 DOI: 10.1080/15216549700205031  1
1997 Appel S, Kumle A, Meier R. Clinical pharmacodynamics of SDZ HTF 919, a new 5-HT4 receptor agonist, in a model of slow colonic transit. Clinical Pharmacology and Therapeutics. 62: 546-55. PMID 9390111 DOI: 10.1016/S0009-9236(97)90050-3  1
1997 Colom LV, Neely A, Diaz ME, Xie WJ, Appel SH. Modulation of septal cell activity by extracellular zinc. Neuroreport. 8: 3081-6. PMID 9331918 DOI: 10.1097/00001756-199709290-00015  1
1997 Engelhardt JI, Siklós L, Appel SH. Immunization of guinea pigs with human choline acetyltransferase induces selective lower motoneuron destruction. Journal of Neuroimmunology. 78: 57-68. PMID 9307228 DOI: 10.1016/S0165-5728(97)00082-9  1
1997 Le WD, Xie WJ, Kong R, Appel SH. Beta-amyloid-induced neurotoxicity of a hybrid septal cell line associated with increased tau phosphorylation and expression of beta-amyloid precursor protein. Journal of Neurochemistry. 69: 978-85. PMID 9282919 DOI: 10.1046/J.1471-4159.1997.69030978.X  1
1997 Colom LV, Alexianu ME, Mosier DR, Smith RG, Appel SH. Amyotrophic lateral sclerosis immunoglobulins increase intracellular calcium in a motoneuron cell line. Experimental Neurology. 146: 354-60. PMID 9270044 DOI: 10.1006/Exnr.1997.6541  1
1997 Kálmán J, Engelhardt JI, Le WD, Xie W, Kovacs I, Kása P, Appel SH. Experimental immune-mediated damage of septal cholinergic neurons. Journal of Neuroimmunology. 77: 63-74. PMID 9209270 DOI: 10.1016/S0165-5728(97)00062-3  1
1997 La Bella V, Goodman JC, Appel SH. Increased CSF glutamate following injection of ALS immunoglobulins. Neurology. 48: 1270-2. PMID 9153455 DOI: 10.1212/Wnl.48.5.1270  1
1997 Le W, Jankovic J, Xie W, Kong R, Appel SH. (-)-Deprenyl protection of 1-methyl-4 phenylpyridium ion (MPP+)-induced apoptosis independent of MAO-B inhibition. Neuroscience Letters. 224: 197-200. PMID 9131670 DOI: 10.1016/S0304-3940(97)00170-5  1
1997 Appel S, Kumle A, Hubert M, Duvauchelle T. First pharmacokinetic-pharmacodynamic study in humans with a selective 5-hydroxytryptamine4 receptor agonist. Journal of Clinical Pharmacology. 37: 229-37. PMID 9089425  1
1997 Engelhardt JI, Siklos L, Appel SH. Altered calcium homeostasis and ultrastructure in motoneurons of mice caused by passively transferred anti-motoneuronal IgG. Journal of Neuropathology and Experimental Neurology. 56: 21-39. PMID 8990126 DOI: 10.1097/00005072-199701000-00003  1
1996 Cooper J, Feldman JM, Jaanus SD, Appleman W, Appel S, Horn D. Pupillary dilation and funduscopy with 1.0% hydroxyamphetamine plus 0.25% tropicamide (Paremyd) versus tropicamide (0.5 or 1.0%) as a function of iris and skin pigmentation, and age. Journal of the American Optometric Association. 67: 669-75. PMID 8979660  0.01
1996 Siklós L, Engelhardt J, Harati Y, Smith RG, Joó F, Appel SH. Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis. Annals of Neurology. 39: 203-16. PMID 8967752 DOI: 10.1002/Ana.410390210  1
1996 Massman PJ, Sims J, Cooke N, Haverkamp LJ, Appel V, Appel SH. Prevalence and correlates of neuropsychological deficits in amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. 61: 450-5. PMID 8937336 DOI: 10.1136/Jnnp.61.5.450  1
1996 Smith RG, Siklos L, Alexianu ME, Engelhardt JI, Mosier DR, Colom L, Habib Mohamed A, Appel SH. Autoimmunity and ALS. Neurology. 47: S40-5; discussion S4. PMID 8858050 DOI: 10.1212/Wnl.47.4_Suppl_2.40S  1
1996 La Bella V, Alexianu ME, Colom LV, Ionescu A, Mohamed AH, Appel SH. Apoptosis induced by beta-N-oxalylamino-L-alanine on a motoneuron hybrid cell line. Neuroscience. 70: 1039-52. PMID 8848166 DOI: 10.1016/0306-4522(95)00401-7  1
1996 Ciner EB, Appel S, Graboyes M, Zambone AM. Assessment and rehabilitation of children with special needs. Optometry Clinics : the Official Publication of the Prentice Society. 5: 187-226. PMID 8837132  0.01
1996 Warner LE, Hilz MJ, Appel SH, Killian JM, Kolodry EH, Karpati G, Carpenter S, Watters GV, Wheeler C, Witt D, Bodell A, Nelis E, Van Broeckhoven C, Lupski JR. Clinical phenotypes of different MPZ (P0) mutations may include Charcot-Marie-Tooth type 1B, Dejerine-Sottas, and congenital hypomyelination. Neuron. 17: 451-60. PMID 8816708 DOI: 10.1016/S0896-6273(00)80177-4  0.01
1996 Appel SD, Yamaguchi H. Laparoscopic cholangiography: a new technique for difficult cannulation. Surgical Laparoscopy & Endoscopy. 6: 5-9. PMID 8808551  1
1996 La Bella V, Ho BK, Appel SH, Smith RG. Calbindin D28K forms a Ca(2+)-dissociable complex with mellitin in vitro. Biochemistry and Molecular Biology International. 38: 1199-210. PMID 8739042  1
1996 Smith RG, Haverkamp LJ, Case S, Appel V, Appel SH. Apolipoprotein E epsilon 4 in bulbar-onset motor neuron disease. Lancet. 348: 334-5. PMID 8709704 DOI: 10.1016/S0140-6736(05)64502-3  1
1996 Ho BK, Alexianu ME, Colom LV, Mohamed AH, Serrano F, Appel SH. Expression of calbindin-D28K in motoneuron hybrid cells after retroviral infection with calbindin-D28K cDNA prevents amyotrophic lateral sclerosis IgG-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 93: 6796-801. PMID 8692898 DOI: 10.1073/Pnas.93.13.6796  1
1996 Appel SH, Smith RG, Le WD. Immune-mediated cell death in neurodegenerative disease. Advances in Neurology. 69: 153-9. PMID 8615124  1
1995 Lee JR, Annegers JF, Appel SH. Prognosis of amyotrophic lateral sclerosis and the effect of referral selection. Journal of the Neurological Sciences. 132: 207-15. PMID 8543950 DOI: 10.1016/0022-510X(95)00154-T  0.01
1995 Mosier DR, Baldelli P, Delbono O, Smith RG, Alexianu ME, Appel SH, Stefani E. Amyotrophic lateral sclerosis immunoglobulins increase Ca2+ currents in a motoneuron cell line. Annals of Neurology. 37: 102-9. PMID 7818241 DOI: 10.1002/Ana.410370119  1
1995 Le W, Xie WJ, Nyormoi O, Ho BK, Smith RG, Appel SH. beta-Amyloid1-40 increases expression of beta-amyloid precursor protein in neuronal hybrid cells. Journal of Neurochemistry. 65: 2373-6. PMID 7595528 DOI: 10.1046/J.1471-4159.1995.65052373.X  1
1995 Le WD, Colom LV, Xie WJ, Smith RG, Alexianu M, Appel SH. Cell death induced by beta-amyloid 1-40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis. Brain Research. 686: 49-60. PMID 7583271 DOI: 10.1016/0006-8993(95)00450-5  1
1995 Appel S, Mathôt RA, Langemeijer MW, IJzerman AP, Danhof M. Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline. British Journal of Pharmacology. 115: 1253-9. PMID 7582553 DOI: 10.1111/j.1476-5381.1995.tb15033.x  0.01
1995 Schneider T, Perez-Reyes E, Nyormoi O, Wei X, Crawford GD, Smith RG, Appel SH, Birnbaumer L. Alpha-1 subunits of voltage gated Ca2+ channels in the mesencephalon x neuroblastoma hybrid cell line MES23.5. Neuroscience. 68: 479-85. PMID 7477958 DOI: 10.1016/0306-4522(95)00147-B  1
1993 Llinás R, Sugimori M, Cherksey BD, Smith RG, Delbono O, Stefani E, Appel S. IgG from amyotrophic lateral sclerosis patients increases current through P-type calcium channels in mammalian cerebellar Purkinje cells and in isolated channel protein in lipid bilayer. Proceedings of the National Academy of Sciences of the United States of America. 90: 11743-7. PMID 8265620 DOI: 10.1073/Pnas.90.24.11743  1
1989 Marcus DM, Latov N, Hsi BP, Gillard BK, Antel J, Appel S, Callegaro L, Daune G, Gillard B, Latoy N, Marcus D, Nobile-Orazio E, Pestronk A, Portoukalian J, Quarles R, et al. Measurement and significance of antibodies against GM1 ganglioside. Report of a workshop, 18 April 1989, Chicago, IL, U.S.A. Journal of Neuroimmunology. 25: 255-259. PMID 2584398 DOI: 10.1016/0165-5728(89)90144-6  0.01
1981 Merickel M, Gray R, Chauvin P, Appel S. Electrophysiology of human muscle in culture Experimental Neurology. 72: 281-293. PMID 7238690 DOI: 10.1016/0014-4886(81)90223-5  1
1981 Merickel M, Gray R, Chauvin P, Appel S. Cultured muscle from myotonic muscular dystrophy patients: Altered membrane electrical properties Proceedings of the National Academy of Sciences of the United States of America. 78: 648-652. PMID 6941262 DOI: 10.1073/Pnas.78.1.648  1
1977 McNamara JO, Appel SH. Biochemical approaches to dementia. Contemporary Neurology Series. 15: 155-68. PMID 144584  1
1977 McNamara JO, Appel SH. Myelin basic protein phosphatase activity in rat brain. Journal of Neurochemistry. 29: 27-35. PMID 69679 DOI: 10.1111/J.1471-4159.1977.Tb03920.X  1
1976 Roses AD, Roses MJ, Miller SE, Hull KL, Appel SH. Carrier detection in Duchenne muscular dystrophy. The New England Journal of Medicine. 294: 193-8. PMID 1244534 DOI: 10.1056/Nejm197601222940404  1
1976 Roses AD, Appel SH. Erythrocyte spectrin peak II phosphorylation in Duchenne muscular dystrophy. Journal of the Neurological Sciences. 29: 185-93. PMID 978207 DOI: 10.1016/0022-510X(76)90170-2  1
1976 Butterfield DA, Roses AD, Appel SH, Chesnut DB. Electron spin resonance studies of membrane proteins in erythrocytes in myotonic muscular dystrophy. Archives of Biochemistry and Biophysics. 177: 226-34. PMID 187121 DOI: 10.1016/0003-9861(76)90432-X  1
1976 Butterfield DA, Chesnut DB, Appel SH, Roses AD. Spin label study of erythrocyte membrane fluidity in myotonic and Duchenne muscular dystrophy and congenital myotonia. Nature. 263: 159-61. PMID 184394 DOI: 10.1038/263159A0  1
1976 Roses AD, Herbstreith M, Metcalf B, Appel SH. Increased phosphorylated components of erythrocyte membrane spectrin band II with reference to Duchenne muscular dystrophy. Journal of the Neurological Sciences. 30: 167-78. PMID 10352 DOI: 10.1016/0022-510X(76)90264-1  1
1976 Miller SE, Roses AD, Appel SH. Scanning electron microscopy studies in muscular dystrophy. Archives of Neurology. 33: 172-4. PMID 3154 DOI: 10.1001/Archneur.1976.00500030028005  1
1975 Miller SE, Roses AD, Appel SH. Letter: Erythrocytes in human muscular dystrophy. Science (New York, N.Y.). 188: 1131. PMID 1215993 DOI: 10.1126/Science.1215993  1
1975 Roses AD, Herbstreith MH, Appel SH. Membrane protein kinase alteration in Duchenne muscular dystrophy. Nature. 254: 350-1. PMID 1118019 DOI: 10.1038/254350A0  1
1975 Roses AD, Appel SH, Butterfield DA, Miller SE, Chesnut DB. Specificity of biochemical and biophysical tests in Duchenne and myotonic muscular dystrophy, carrier states, and congenital myotonia. Transactions of the American Neurological Association. 100: 131-4. PMID 179179  1
1975 Roses AD, Butterfield A, Appel SH, Chestnut DB. Phenytoin and membrane fluidity in myotonic dystrophy. Archives of Neurology. 32: 535-8. PMID 168843 DOI: 10.1001/Archneur.1975.00490500055006  1
1975 Roses AD, Appel SH. Phosphorylation of component a of the human erythrocyte membrane in myotonic muscular dystrophy. The Journal of Membrane Biology. 20: 51-8. PMID 123592 DOI: 10.1007/Bf01870627  1
1974 Butterfield DA, Roses AD, Cooper ML, Appel SH, Chesnut DB. A comparative electron spin resonance study of the erythrocyte membrane in myotonic muscular dystrophy. Biochemistry. 13: 5078-82. PMID 4373028  1
1974 Butterfield DA, Chesnut DB, Roses AD, Appel SH. Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 71: 909-13. PMID 4362637 DOI: 10.1073/Pnas.71.3.909  1
1974 Roses AD, Appel SH. Muscle membrane protein kinase in myotonic muscular dystrophy. Nature. 250: 245-7. PMID 4277586 DOI: 10.1038/250245A0  1
1974 Roses AD, Appel SH. Letter: Muscular dystrophies. Lancet (London, England). 2: 1400. PMID 4143368  1
1973 Andrew CG, Roses AD, Almon RR, Appel SH. Phosphorylation of muscle membranes: identification of a membrane-bound protein kinase. Science (New York, N.Y.). 182: 927-9. PMID 4355523 DOI: 10.1126/Science.182.4115.927  1
1973 Roses AD, Appel SH. Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 70: 1855-9. PMID 4352659 DOI: 10.1073/Pnas.70.6.1855  1
1973 Roses AD, Appel SH. Erythrocyte protein phosphorylation. The Journal of Biological Chemistry. 248: 1408-11. PMID 4346955  1
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