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Allison D. Ebert, Ph.D. - Publications

Affiliations: 
Northwestern University, Evanston, IL 
Area:
Parkinson's Disease
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Adelman JW, Rosas-Rogers S, Schumacher ML, Mokry RL, Terhune SS, Ebert AD. Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical Neurons. Biorxiv : the Preprint Server For Biology. PMID 36945635 DOI: 10.1101/2023.03.03.531045  0.319
2020 Seminary ER, Santarriaga S, Wheeler L, Mejaki M, Abrudan J, Demos W, Zimmermann MT, Urrutia RA, Fee D, Barkhaus PE, Ebert AD. Motor Neuron Generation from iPSCs from Identical Twins Discordant for Amyotrophic Lateral Sclerosis. Cells. 9. PMID 32121108 DOI: 10.3390/Cells9030571  0.368
2019 Kaifer KA, Villalón E, O'Brien BS, Sison SL, Smith CE, Simon ME, Marquez J, O'Day S, Hopkins AE, Neff R, Rindt H, Ebert AD, Lorson CL. AAV9-Mediated Delivery of miR-23a Reduces Disease Severity in Smn2B-/SMA Model Mice. Human Molecular Genetics. PMID 31211843 DOI: 10.1093/Hmg/Ddz142  0.309
2019 Logan S, Arzua T, Canfield SG, Seminary ER, Sison SL, Ebert AD, Bai X. Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models. Comprehensive Physiology. 9: 565-611. PMID 30873582 DOI: 10.1002/Cphy.C180025  0.301
2018 Sison SL, Vermilyea SC, Emborg ME, Ebert AD. Using Patient-Derived Induced Pluripotent Stem Cells to Identify Parkinson's Disease-Relevant Phenotypes. Current Neurology and Neuroscience Reports. 18: 84. PMID 30284665 DOI: 10.1007/S11910-018-0893-8  0.381
2018 Seminary ER, Sison SL, Ebert AD. Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons. Frontiers in Neuroscience. 12: 86. PMID 29515358 DOI: 10.3389/Fnins.2018.00086  0.384
2017 Gray KM, Kaifer KA, Baillat D, Wen Y, Bonacci TR, Ebert AD, Raimer AC, Spring AM, Have ST, Glascock JJ, Gupta K, Van Duyne GD, Emanuele MJ, Lamond AI, Wagner EJ, et al. Self-oligomerization regulates stability of Survival Motor Neuron (SMN) protein isoforms by sequestering an SCF(Slmb) degron. Molecular Biology of the Cell. PMID 29167380 DOI: 10.1091/Mbc.E17-11-0627  0.355
2017 Schwab AJ, Sison SL, Meade MR, Broniowska KA, Corbett JA, Ebert AD. Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons. Stem Cell Reports. PMID 29129681 DOI: 10.1016/J.Stemcr.2017.10.010  0.373
2017 Sison SL, Patitucci TN, Seminary ER, Villalon E, Lorson CL, Ebert AD. Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy. Human Molecular Genetics. PMID 28637335 DOI: 10.1093/Hmg/Ddx230  0.358
2016 Osman EY, Washington CW, Kaifer KA, Mazzasette C, Patitucci TN, Florea KM, Simon ME, Ko CP, Ebert AD, Lorson CL. Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27401142 DOI: 10.1038/Mt.2016.145  0.333
2016 Bigley TM, McGivern JV, Ebert AD, Terhune SS. Impact of a Cytomegalovirus Kinase Inhibitor on Infection and Neuronal Progenitor Cell Differentiation. Antiviral Research. PMID 26875788 DOI: 10.1016/J.Antiviral.2016.02.007  0.365
2015 Schwab AJ, Ebert AD. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports. 5: 1039-52. PMID 26651604 DOI: 10.1016/J.Stemcr.2015.11.004  0.396
2015 Patitucci TN, Ebert AD. SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons. Human Molecular Genetics. PMID 26643950 DOI: 10.1093/Hmg/Ddv489  0.347
2015 Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL. Astrocytes influence the severity of spinal muscular atrophy. Human Molecular Genetics. 24: 4094-102. PMID 25911676 DOI: 10.1093/Hmg/Ddv148  0.383
2015 Yu H, Fischer G, Ebert AD, Wu HE, Bai X, Hogan QH. Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results. Molecular Pain. 11: 5. PMID 25888914 DOI: 10.1186/S12990-015-0002-9  0.341
2014 Schwab AJ, Ebert AD. Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy. Plos One. 9: e103112. PMID 25054590 DOI: 10.1371/Journal.Pone.0103112  0.427
2014 Hosoyama T, McGivern JV, Van Dyke JM, Ebert AD, Suzuki M. Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture. Stem Cells Translational Medicine. 3: 564-74. PMID 24657962 DOI: 10.5966/Sctm.2013-0143  0.357
2014 McGivern JV, Ebert AD. Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments. Advanced Drug Delivery Reviews. 69: 170-8. PMID 24309014 DOI: 10.1016/J.Addr.2013.11.012  0.311
2013 McGivern JV, Patitucci TN, Nord JA, Barabas ME, Stucky CL, Ebert AD. Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production. Glia. 61: 1418-28. PMID 23839956 DOI: 10.1002/Glia.22522  0.399
2013 Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN. EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs. Stem Cell Research. 10: 417-27. PMID 23474892 DOI: 10.1016/J.Scr.2013.01.009  0.355
2012 Ebert AD. Modeling neurodegenerative diseases using stem cells: is it accelerating drug discovery? Future Medicinal Chemistry. 4: 1651-3. PMID 22924501 DOI: 10.4155/Fmc.12.101  0.33
2012 Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN. Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. Plos One. 7: e39113. PMID 22723941 DOI: 10.1371/Journal.Pone.0039113  0.435
2012 Mattis V, Svendsen S, Ebert A, Svendsen C, King A, Casale M, Winokur S, Batugedara G, Vawter M, Donovan P, Lock L, Thompson L, Zhu Y, Fossale E, Atwal R, et al. A11 Induced pluripotent stem cells for basic and translational research on HD Journal of Neurology, Neurosurgery & Psychiatry. 83: A3.2-A4. DOI: 10.1136/Jnnp-2012-303524.11  0.441
2012 Mattis VB, Svendsen SP, Ebert A, Svendsen CN, King AR, Casale M, Winokur ST, Batugedara G, Vawter M, Donovan PJ, Lock LF, Thompson LM, Zhu Y, Fossale E, Atwal RS, et al. Induced pluripotent stem cells from patients with huntington’s disease show CAG repeat expansion associated phenotypes Cell Stem Cell. 11: 264-278. DOI: 10.1016/J.Stem.2012.04.027  0.402
2010 Jodelka FM, Ebert AD, Duelli DM, Hastings ML. A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Human Molecular Genetics. 19: 4906-17. PMID 20884664 DOI: 10.1093/Hmg/Ddq425  0.337
2010 Ebert AD, Svendsen CN. Stem cell model of spinal muscular atrophy. Archives of Neurology. 67: 665-9. PMID 20558385 DOI: 10.1001/Archneurol.2010.89  0.384
2010 Ebert AD, Svendsen CN. Human stem cells and drug screening: opportunities and challenges. Nature Reviews. Drug Discovery. 9: 367-72. PMID 20339370 DOI: 10.1038/Nrd3000  0.337
2010 Ebert AD, Barber AE, Heins BM, Svendsen CN. Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease. Experimental Neurology. 224: 155-62. PMID 20227407 DOI: 10.1016/J.Expneurol.2010.03.005  0.423
2009 Sareen D, McMillan E, Ebert AD, Shelley BC, Johnson JA, Meisner LF, Svendsen CN. Chromosome 7 and 19 trisomy in cultured human neural progenitor cells. Plos One. 4: e7630. PMID 19898616 DOI: 10.1371/Journal.Pone.0007630  0.33
2009 Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiology of Disease. 36: 303-11. PMID 19660547 DOI: 10.1016/J.Nbd.2009.07.022  0.301
2009 Mattis VB, Ebert AD, Fosso MY, Chang CW, Lorson CL. Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model. Human Molecular Genetics. 18: 3906-13. PMID 19625298 DOI: 10.1093/Hmg/Ddp333  0.375
2009 Ebert AD, Yu J, Rose FF, Mattis VB, Lorson CL, Thomson JA, Svendsen CN. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature. 457: 277-80. PMID 19098894 DOI: 10.1038/Nature07677  0.42
2008 Behrstock S, Ebert AD, Klein S, Schmitt M, Moore JM, Svendsen CN. Lesion-induced increase in survival and migration of human neural progenitor cells releasing GDNF. Cell Transplantation. 17: 753-62. PMID 19044202 DOI: 10.3727/096368908786516819  0.37
2008 Ebert AD, McMillan EL, Svendsen CN. Isolating, expanding, and infecting human and rodent fetal neural progenitor cells. Current Protocols in Stem Cell Biology. Unit 2D.2. PMID 18819085 DOI: 10.1002/9780470151808.Sc02D02S6  0.338
2008 Emborg ME, Ebert AD, Moirano J, Peng S, Suzuki M, Capowski E, Joers V, Roitberg BZ, Aebischer P, Svendsen CN. GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplantation. 17: 383-95. PMID 18522241 DOI: 10.3727/096368908784423300  0.334
2008 Ebert AD, Beres AJ, Barber AE, Svendsen CN. Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease. Experimental Neurology. 209: 213-23. PMID 18061591 DOI: 10.1016/J.Expneurol.2007.09.022  0.378
2008 Ebert AD, Hann HJ, Bohn MC. Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of Parkinson's disease does not involve activation of caspase-9 and caspase-3. Journal of Neuroscience Research. 86: 317-25. PMID 17787016 DOI: 10.1002/Jnr.21480  0.599
2007 Capowski EE, Schneider BL, Ebert AD, Seehus CR, Szulc J, Zufferey R, Aebischer P, Svendsen CN. Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy. Journal of Neuroscience Methods. 163: 338-49. PMID 17397931 DOI: 10.1016/J.Jneumeth.2007.02.022  0.375
2006 Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ. Differentiated dopaminergic MN9D cells only partially recapitulate the electrophysiological properties of midbrain dopaminergic neurons. Developmental Neuroscience. 28: 528-37. PMID 17028430 DOI: 10.1159/000095115  0.629
2006 Behrstock S, Ebert A, McHugh J, Vosberg S, Moore J, Schneider B, Capowski E, Hei D, Kordower J, Aebischer P, Svendsen CN. Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Therapy. 13: 379-88. PMID 16355116 DOI: 10.1038/Sj.Gt.3302679  0.394
2006 Zhao P, Awosika W, Wu N, Macias F, Cepeda C, Levine M, Vellis Jd, Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ, Espinosa-Jeffrey A, Lv X, Wang N, et al. Contents Vol. 28, 2006 Developmental Neuroscience. 28: 555-557. DOI: 10.1159/000096120  0.49
2006 Zhao P, Awosika W, Wu N, Macias F, Cepeda C, Levine M, Vellis Jd, Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ, Espinosa-Jeffrey A, Lv X, Wang N, et al. Subject Index Vol. 28, 2006 Developmental Neuroscience. 28: 553-554. DOI: 10.1159/000096119  0.496
2006 Emborg M, Peng S, Moirano J, Ebert A, Suzuki M, Capowski B, Joers V, Roitberg B, Aebischer P, Svendsen C. Survival of human neural stem cells (HNSCs) expressing GDNF in mptp-treated rhesus monkeys Experimental Neurology. 198: 567. DOI: 10.1016/J.Expneurol.2006.02.039  0.335
2005 Ebert AD, Svendsen CN. A new tool in the battle against Alzheimer's disease and aging: ex vivo gene therapy. Rejuvenation Research. 8: 131-4. PMID 16144466 DOI: 10.1089/Rej.2005.8.131  0.34
2005 Ebert AD, Chen F, He X, Cryns VL, Bohn MC. A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo. Experimental Neurology. 191: S80-94. PMID 15629764 DOI: 10.1016/J.Expneurol.2004.08.024  0.622
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