Ricardo E. Dolmetsch - Publications

Affiliations: 
Stanford University, Palo Alto, CA 

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sun Y, Paşca SP, Portmann T, Goold C, Worringer KA, Guan W, Chan KC, Gai H, Vogt D, Chen YJ, Mao R, Chan K, Rubenstein JL, Madison DV, Hallmayer J, ... ... Dolmetsch RE, et al. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients. Elife. 5. PMID 27458797 DOI: 10.7554/eLife.13073  0.76
2015 Tsuruta F, Dolmetsch RE. PIKfyve mediates the motility of late endosomes and lysosomes in neuronal dendrites. Neuroscience Letters. 605: 18-23. PMID 26232680 DOI: 10.1016/j.neulet.2015.07.021  1
2015 Rana A, Yen M, Sadaghiani AM, Malmersjö S, Park CY, Dolmetsch RE, Lewis RS. Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels. The Journal of Cell Biology. 209: 653-70. PMID 26033257 DOI: 10.1083/jcb.201412060  1
2015 Byers B, Lee HJ, Liu J, Weitz AJ, Lin P, Zhang P, Shcheglovitov A, Dolmetsch R, Pera RR, Lee JH. Direct in vivo assessment of human stem cell graft-host neural circuits. Neuroimage. 114: 328-37. PMID 25936696 DOI: 10.1016/j.neuroimage.2015.03.079  1
2015 Yang M, Mahrt EJ, Lewis F, Foley G, Portmann T, Dolmetsch RE, Portfors CV, Crawley JN. 16p11.2 Deletion Syndrome Mice Display Sensory and Ultrasonic Vocalization Deficits During Social Interactions. Autism Research : Official Journal of the International Society For Autism Research. PMID 25663600 DOI: 10.1002/aur.1465  1
2014 Tian Y, Voineagu I, Pa?ca SP, Won H, Chandran V, Horvath S, Dolmetsch RE, Geschwind DH. Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. Genome Medicine. 6: 75. PMID 25360157 DOI: 10.1186/s13073-014-0075-5  1
2014 Sadaghiani AM, Lee SM, Odegaard JI, Leveson-Gower DB, McPherson OM, Novick P, Kim MR, Koehler AN, Negrin R, Dolmetsch RE, Park CY. Identification of Orai1 channel inhibitors by using minimal functional domains to screen small molecule microarrays. Chemistry & Biology. 21: 1278-92. PMID 25308275 DOI: 10.1016/j.chembiol.2014.08.016  1
2014 PaÅŸca SP, Panagiotakos G, Dolmetsch RE. Generating human neurons in vitro and using them to understand neuropsychiatric disease. Annual Review of Neuroscience. 37: 479-501. PMID 25002278 DOI: 10.1146/annurev-neuro-062012-170328  1
2014 Portmann T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, Bader PL, Grueter BA, Goold C, Fisher E, Clifford K, Rengarajan P, Kalikhman D, Loureiro D, Saw NL, ... ... Dolmetsch RE, et al. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Reports. 7: 1077-92. PMID 24794428 DOI: 10.1016/j.celrep.2014.03.036  1
2013 Dolmetsch R. Straight talk with... Ricardo Dolmetsch. Interview by Elie Dolgin Nature Medicine. 19: 1360. PMID 24202377  1
2013 Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, Dolmetsch RE. SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature. 503: 267-71. PMID 24132240 DOI: 10.1038/nature12618  1
2013 Yucel G, Altindag B, Gomez-Ospina N, Rana A, Panagiotakos G, Lara MF, Dolmetsch R, Oro AE. State-dependent signaling by Cav1.2 regulates hair follicle stem cell function. Genes & Development. 27: 1217-22. PMID 23752588 DOI: 10.1101/gad.216556.113  1
2013 Hall DD, Dai S, Tseng PY, Malik Z, Nguyen M, Matt L, Schnizler K, Shephard A, Mohapatra DP, Tsuruta F, Dolmetsch RE, Christel CJ, Lee A, Burette A, Weinberg RJ, et al. Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2. Neuron. 78: 483-97. PMID 23664615 DOI: 10.1016/j.neuron.2013.02.032  1
2013 Gomez-Ospina N, Panagiotakos G, Portmann T, Pasca SP, Rabah D, Budzillo A, Kinet JP, Dolmetsch RE. A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT. Plos One. 8: e60526. PMID 23613729 DOI: 10.1371/journal.pone.0060526  1
2013 Ramachandran KV, Hennessey JA, Barnett AS, Yin X, Stadt HA, Foster E, Shah RA, Yazawa M, Dolmetsch RE, Kirby ML, Pitt GS. Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development. The Journal of Clinical Investigation. 123: 1638-46. PMID 23549079 DOI: 10.1172/JCI66903  1
2013 Takahashi M, Obayashi M, Ishiguro T, Sato N, Niimi Y, Ozaki K, Mogushi K, Mahmut Y, Tanaka H, Tsuruta F, Dolmetsch R, Yamada M, Takahashi H, Kato T, Mori O, et al. Cytoplasmic location of α1A voltage-gated calcium channel C-terminal fragment (Cav2.1-CTF) aggregate is sufficient to cause cell death. Plos One. 8: e50121. PMID 23505410 DOI: 10.1371/journal.pone.0050121  1
2013 Wang Y, Dolmetsch R. In vitro human corticogenesis. Neuron. 77: 379-81. PMID 23395367 DOI: 10.1016/j.neuron.2013.01.023  1
2013 Krey JF, PaÅŸca SP, Shcheglovitov A, Yazawa M, Schwemberger R, Rasmusson R, Dolmetsch RE. Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. Nature Neuroscience. 16: 201-9. PMID 23313911 DOI: 10.1038/nn.3307  1
2013 Yazawa M, Dolmetsch RE. Modeling Timothy syndrome with iPS cells. Journal of Cardiovascular Translational Research. 6: 1-9. PMID 23299782 DOI: 10.1007/s12265-012-9444-x  1
2013 Dolmetsch R. Straight talk with Nature Medicine. 19: 1360. DOI: 10.1038/nm1113-1360  1
2012 Tadmouri A, Kiyonaka S, Barbado M, Rousset M, Fablet K, Sawamura S, Bahembera E, Pernet-Gallay K, Arnoult C, Miki T, Sadoul K, Gory-Faure S, Lambrecht C, Lesage F, Akiyama S, ... ... Dolmetsch R, et al. Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy. The Embo Journal. 31: 3730-44. PMID 22892567 DOI: 10.1038/emboj.2012.226  1
2012 Wang IN, Wang X, Ge X, Anderson J, Ho M, Ashley E, Liu J, Butte MJ, Yazawa M, Dolmetsch RE, Quertermous T, Yang PC. Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells. Plos One. 7: e38328. PMID 22675543 DOI: 10.1371/journal.pone.0038328  1
2012 Sun N, Yazawa M, Liu J, Han L, Sanchez-Freire V, Abilez OJ, Navarrete EG, Hu S, Wang L, Lee A, Pavlovic A, Lin S, Chen R, Hajjar RJ, Snyder MP, ... Dolmetsch RE, et al. Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Science Translational Medicine. 4: 130ra47. PMID 22517884 DOI: 10.1126/scitranslmed.3003552  1
2011 Pa?ca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Pa?ca AM, Cord B, Palmer TD, Chikahisa S, Nishino S, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE. Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nature Medicine. 17: 1657-62. PMID 22120178 DOI: 10.1038/nm.2576  1
2011 Yoo AS, Sun AX, Li L, Shcheglovitov A, Portmann T, Li Y, Lee-Messer C, Dolmetsch RE, Tsien RW, Crabtree GR. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature. 476: 228-31. PMID 21753754 DOI: 10.1038/nature10323  1
2011 Dolmetsch R, Geschwind DH. The human brain in a dish: the promise of iPSC-derived neurons. Cell. 145: 831-4. PMID 21663789 DOI: 10.1016/j.cell.2011.05.034  1
2011 Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, Kee K, Schüle B, Dolmetsch RE, Langston W, Palmer TD, Pera RR. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell. 8: 267-80. PMID 21362567 DOI: 10.1016/j.stem.2011.01.013  1
2011 Yazawa M, Hsueh B, Jia X, Pasca AM, Bernstein JA, Hallmayer J, Dolmetsch RE. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature. 471: 230-4. PMID 21307850 DOI: 10.1038/nature09855  1
2010 Park CY, Shcheglovitov A, Dolmetsch R. The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. Science (New York, N.Y.). 330: 101-5. PMID 20929812 DOI: 10.1126/science.1191027  1
2010 Rana A, Dolmetsch RE. Using light to control signaling cascades in live neurons. Current Opinion in Neurobiology. 20: 617-22. PMID 20850295 DOI: 10.1016/j.conb.2010.08.018  1
2010 Ishiguro T, Ishikawa K, Takahashi M, Obayashi M, Amino T, Sato N, Sakamoto M, Fujigasaki H, Tsuruta F, Dolmetsch R, Arai T, Sasaki H, Nagashima K, Kato T, Yamada M, et al. The carboxy-terminal fragment of alpha(1A) calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells. Acta Neuropathologica. 119: 447-64. PMID 20043227 DOI: 10.1007/s00401-009-0630-0  1
2009 Tsuruta F, Green EM, Rousset M, Dolmetsch RE. PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death. The Journal of Cell Biology. 187: 279-94. PMID 19841139 DOI: 10.1083/jcb.200903028  1
2009 Eroglu C, Allen NJ, Susman MW, O'Rourke NA, Park CY, Ozkan E, Chakraborty C, Mulinyawe SB, Annis DS, Huberman AD, Green EM, Lawler J, Dolmetsch R, Garcia KC, Smith SJ, et al. Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. Cell. 139: 380-92. PMID 19818485 DOI: 10.1016/j.cell.2009.09.025  1
2009 Yazawa M, Sadaghiani AM, Hsueh B, Dolmetsch RE. Induction of protein-protein interactions in live cells using light. Nature Biotechnology. 27: 941-5. PMID 19801976 DOI: 10.1038/nbt.1569  1
2009 Mullins FM, Park CY, Dolmetsch RE, Lewis RS. STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels. Proceedings of the National Academy of Sciences of the United States of America. 106: 15495-500. PMID 19706428 DOI: 10.1073/pnas.0906781106  1
2009 Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, Walz T, Garcia KC, Dolmetsch RE, Lewis RS. STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell. 136: 876-90. PMID 19249086 DOI: 10.1016/j.cell.2009.02.014  1
2009 Barreto-Chang OL, Dolmetsch RE. Calcium imaging of cortical neurons using Fura-2 AM. Journal of Visualized Experiments : Jove. PMID 19229178 DOI: 10.3791/1067  1
2008 Gomez-Ospina N, Dolmetsch R. L-type channel regulation of gene expression Transcriptional Regulation by Neuronal Activity: to the Nucleus and Back. 111-123. DOI: 10.1007/978-0-387-73609-9_6  1
2007 Brenner JS, Dolmetsch RE. TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size. Plos One. 2: e802. PMID 17726532 DOI: 10.1371/journal.pone.0000802  1
2007 Green EM, Barrett CF, Bultynck G, Shamah SM, Dolmetsch RE. The tumor suppressor eIF3e mediates calcium-dependent internalization of the L-type calcium channel CaV1.2. Neuron. 55: 615-32. PMID 17698014 DOI: 10.1016/j.neuron.2007.07.024  1
2007 Green E, Dolmetsch RE. Calcium channels light up. Nature Chemical Biology. 3: 369-70. PMID 17576420 DOI: 10.1038/nchembio0707-369  1
2007 Krey JF, Dolmetsch RE. Molecular mechanisms of autism: a possible role for Ca2+ signaling. Current Opinion in Neurobiology. 17: 112-9. PMID 17275285 DOI: 10.1016/j.conb.2007.01.010  1
2007 Brenner J, Gomez-Ospina N, Dolmetsch R. Temporal and spatial regulation of calcium-dependent transcription New Comprehensive Biochemistry. 41: 403-423. DOI: 10.1016/S0167-7306(06)41015-2  1
2006 Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L, Dolmetsch R. The C Terminus of the L-Type Voltage-Gated Calcium Channel CaV1.2 Encodes a Transcription Factor Cell. 127: 591-606. PMID 17081980 DOI: 10.1016/j.cell.2006.10.017  1
2003 Dolmetsch R. Excitation-transcription coupling: signaling by ion channels to the nucleus Science's Stke : Signal Transduction Knowledge Environment. 2003: PE4. PMID 12538881  1
2002 Spotts JM, Dolmetsch RE, Greenberg ME. Time-lapse imaging of a dynamic phosphorylation-dependent protein-protein interaction in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 99: 15142-7. PMID 12415118 DOI: 10.1073/pnas.232565699  1
2002 Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch RE, Griffith EC, Hu LS, Haddad C, Xia Z, Greenberg ME. CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. Neuron. 34: 221-33. PMID 11970864 DOI: 10.1016/S0896-6273(02)00655-4  1
2001 Dolmetsch RE, Pajvani U, Fife K, Spotts JM, Greenberg ME. Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. Science (New York, N.Y.). 294: 333-9. PMID 11598293 DOI: 10.1126/science.1063395  1
2001 West AE, Chen WG, Dalva MB, Dolmetsch RE, Kornhauser JM, Shaywitz AJ, Takasu MA, Tao X, Greenberg ME. Calcium regulation of neuronal gene expression. Proceedings of the National Academy of Sciences of the United States of America. 98: 11024-31. PMID 11572963 DOI: 10.1073/pnas.191352298  1
2001 Feske S, Giltnane J, Dolmetsch R, Staudt LM, Rao A. Gene regulation mediated by calcium signals in T lymphocytes Nature Immunology. 2: 316-324. PMID 11276202 DOI: 10.1038/86318  1
1998 Healy JI, Dolmetsch RE, Lewis RS, Goodnow CC. Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytes. Novartis Foundation Symposium. 215: 137-44; discussion 1. PMID 9760576  1
1998 Bergling S, Dolmetsch R, Lewis RS, Keizer J. A fluorometric method for estimating the calcium content of internal stores. Cell Calcium. 23: 251-9. PMID 9681188 DOI: 10.1016/S0143-4160(98)90123-3  1
1998 Dolmetsch RE, Xu K, Lewis RS. Calcium oscillations increase the efficiency and specificity of gene expression. Nature. 392: 933-6. PMID 9582075 DOI: 10.1038/31960  1
1997 Healy JI, Dolmetsch RE, Timmerman LA, Cyster JG, Thomas ML, Crabtree GR, Lewis RS, Goodnow CC. Different nuclear signals are activated by the B cell receptor during positive versus negative signaling. Immunity. 6: 419-28. PMID 9133421  1
1997 Dolmetsch RE, Lewis RS, Goodnow CC, Healy JI. Differential activation of transcription factors induced by Ca2+ response amplitude and duration. Nature. 386: 855-8. PMID 9126747 DOI: 10.1038/386855a0  1
1997 Fanger CM, Zweifach A, Dolmetsch RE, Hoth M, Lewis RS. Function follows form: The role of store-operated calcium channels in T-cell activation Cellular Physiology and Biochemistry. 7: 203-218.  1
1996 Lewis RS, Dolmetsch RE, Zweifach A. Positive and negative regulation of depletion-activated calcium channels by calcium. Society of General Physiologists Series. 51: 241-54. PMID 8809948  1
1994 Dolmetsch RE, Lewis RS. Signaling between intracellular Ca2+ stores and depletion-activated Ca2+ channels generates [Ca2+]i oscillations in T lymphocytes. The Journal of General Physiology. 103: 365-88. PMID 8195779  1
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