Year |
Citation |
Score |
2019 |
Wang Q, Corey RA, Hedger G, Aryal P, Grieben M, Nasrallah C, Baronina A, Pike ACW, Shi J, Carpenter EP, Sansom MSP. Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2. Structure (London, England : 1993). PMID 31806353 DOI: 10.1016/J.Str.2019.11.005 |
0.624 |
|
2019 |
Wang Q, Hedger G, Aryal P, Grieben M, Pike AC, Shi J, Carpenter EP, Sansom MS. Understanding Protein-Lipid Interactions of TRP Channels of the Polycystin Family, through MD Simulations and Structural Studies Biophysical Journal. 116: 534a-535a. DOI: 10.1016/J.Bpj.2018.11.2877 |
0.671 |
|
2019 |
Cullinan M, Aryal P, Bankston J. Measuring Dynamics of the Acid-Sensing Ion Channel N-Terminus using Transition Metal Ion FRET Biophysical Journal. 116: 35a-36a. DOI: 10.1016/J.Bpj.2018.11.236 |
0.456 |
|
2018 |
Wang Q, Hedger G, Aryal P, Shi J, Carpenter EP, Sansom MS. A PIP2 Binding Site on a Human TRP Channel: Simulation Studies of PKD2 Biophysical Journal. 114: 397a. DOI: 10.1016/J.Bpj.2017.11.2196 |
0.638 |
|
2017 |
Nematian-Ardestani E, Jarerattanachat V, Aryal P, Sansom MSP, Tucker SJ. The Effects of Stretch Activation on Ionic Selectivity of the TREK-2 K2P K(+) Channel. Channels (Austin, Tex.). 0. PMID 28723241 DOI: 10.1080/19336950.2017.1356955 |
0.703 |
|
2017 |
Lacin E, Aryal P, Glaaser IW, Bodhinathan K, Tsai E, Marsh N, Tucker SJ, Sansom MSP, Slesinger PA. Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of General Physiology. PMID 28720589 DOI: 10.1085/Jgp.201711801 |
0.788 |
|
2017 |
Aryal P, Jarerattanachat V, Clausen MV, Schewe M, McClenaghan C, Argent L, Conrad LJ, Dong YY, Pike AC, Carpenter EP, Baukrowitz T, Sansom MS, Tucker SJ. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel. Structure (London, England : 1993). PMID 28392258 DOI: 10.1016/J.Str.2017.03.006 |
0.815 |
|
2017 |
Jarerattanachat V, Clausen MV, Aryal P, Carpenter EP, Sansom MS, Tucker SJ. Structural and Functional Response of a Mechanosensitive K2P K + Channel to Asymmetric Membrane Tension Biophysical Journal. 112: 545a. DOI: 10.1016/J.Bpj.2016.11.2945 |
0.73 |
|
2017 |
Klesse G, Trick J, Chelvaniththilan S, Aryal P, Wallace J, Tucker S, Sansom MSP. Hydrophobic Gating and Functional Annotation of Ion Channel Structures by Molecular Dynamics Simulations Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2233 |
0.729 |
|
2016 |
Trick JL, Chelvaniththilan S, Klesse G, Aryal P, Wallace EJ, Tucker SJ, Sansom MS. Functional Annotation of Ion Channel Structures by Molecular Simulation. Structure (London, England : 1993). PMID 27866853 DOI: 10.1016/J.Str.2016.10.005 |
0.755 |
|
2016 |
McClenaghan C, Schewe M, Aryal P, Carpenter EP, Baukrowitz T, Tucker SJ. Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states. The Journal of General Physiology. 147: 497-505. PMID 27241700 DOI: 10.1085/Jgp.201611601 |
0.808 |
|
2016 |
Aryal P, Jarerattanachat V, Tucker SJ, Sansom MS. Bilayer-Mediated Structural Transitions in the TREK-2 Mechanosensitive K2P Channel Biophysical Journal. 110: 348a. DOI: 10.1016/J.Bpj.2015.11.1874 |
0.818 |
|
2015 |
Trick JL, Aryal P, Tucker SJ, Sansom MS. Molecular simulation studies of hydrophobic gating in nanopores and ion channels. Biochemical Society Transactions. 43: 146-50. PMID 25849908 DOI: 10.1042/Bst20140256 |
0.783 |
|
2015 |
Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, et al. K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science (New York, N.Y.). 347: 1256-9. PMID 25766236 DOI: 10.1126/Science.1261512 |
0.821 |
|
2015 |
Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ. Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel. Channels (Austin, Tex.). 9: 44-9. PMID 25487004 DOI: 10.4161/19336950.2014.981987 |
0.733 |
|
2015 |
Aryal P, Sansom MS, Tucker SJ. Hydrophobic gating in ion channels. Journal of Molecular Biology. 427: 121-30. PMID 25106689 DOI: 10.1016/J.Jmb.2014.07.030 |
0.747 |
|
2015 |
Aryal P, Tucker SJ, Sansom MS. Understanding the Dynamics of K2P Channels in Complex Lipid Bilayers Biophysical Journal. 108: 436a-437a. DOI: 10.1016/J.Bpj.2014.11.2384 |
0.813 |
|
2014 |
Aryal P, Abd-Wahab F, Bucci G, Sansom MS, Tucker SJ. A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel. Nature Communications. 5: 4377. PMID 25001086 DOI: 10.1038/Ncomms5377 |
0.804 |
|
2013 |
Schmidt MR, Aryal P, Tucker SJ, Sansom MS. K2P and Kir K+ Channels in Physiological Bilayers Biophysical Journal. 104: 132a. DOI: 10.1016/J.Bpj.2012.11.754 |
0.796 |
|
2012 |
Almeida MC, Hew-Butler T, Soriano RN, Rao S, Wang W, Wang J, Tamayo N, Oliveira DL, Nucci TB, Aryal P, Garami A, Bautista D, Gavva NR, Romanovsky AA. Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2086-99. PMID 22323721 DOI: 10.1523/Jneurosci.5606-11.2012 |
0.54 |
|
2010 |
Aryal P, Dvir H, Choe S, Slesinger PA. Identification of the Alcohol Activation Site in GIRK Channels Biophysical Journal. 98: 700a. DOI: 10.1016/J.Bpj.2009.12.3840 |
0.743 |
|
2009 |
Aryal P, Dvir H, Choe S, Slesinger PA. A discrete alcohol pocket involved in GIRK channel activation. Nature Neuroscience. 12: 988-95. PMID 19561601 DOI: 10.1038/Nn.2358 |
0.707 |
|
2009 |
Aryal P, Dvir H, Choe S, Slesinger PA. Evidence for a Discrete Alcohol Pocket Mediating GIRK Channel Activation Biophysical Journal. 96: 463a. DOI: 10.1016/J.Bpj.2008.12.2387 |
0.734 |
|
2007 |
Fowler CE, Aryal P, Suen KF, Slesinger PA. Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. The Journal of Physiology. 580: 51-65. PMID 17185339 DOI: 10.1113/Jphysiol.2006.123216 |
0.609 |
|
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