Sean G. Megason, Ph.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
sonic hedgehog, patterning, nervous system

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hiscock TW, Megason SG. Orientation of Turing-like Patterns by Morphogen Gradients and Tissue Anisotropies. Cell Systems. 1: 408-416. PMID 26771020 DOI: 10.1016/j.cels.2015.12.001  0.72
2015 Swinburne IA, Mosaliganti KR, Green AA, Megason SG. Improved Long-Term Imaging of Embryos with Genetically Encoded α-Bungarotoxin. Plos One. 10: e0134005. PMID 26244658 DOI: 10.1371/journal.pone.0134005  0.72
2015 Xiong F, Obholzer ND, Noche RR, Megason SG. Multibow: digital spectral barcodes for cell tracing. Plos One. 10: e0127822. PMID 26010570 DOI: 10.1371/journal.pone.0127822  0.72
2015 Xiong F, Megason SG. Abstracting the principles of development using imaging and modeling. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 633-42. PMID 25946995 DOI: 10.1039/c5ib00025d  0.72
2015 Stooke-Vaughan GA, Obholzer ND, Baxendale S, Megason SG, Whitfield TT. Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin. Development (Cambridge, England). 142: 1137-45. PMID 25758224 DOI: 10.1242/dev.116632  0.72
2015 Hiscock TW, Megason SG. Mathematically guided approaches to distinguish models of periodic patterning. Development (Cambridge, England). 142: 409-19. PMID 25605777 DOI: 10.1242/dev.107441  0.72
2014 Xiong F, Ma W, Hiscock TW, Mosaliganti KR, Tentner AR, Brakke KA, Rannou N, Gelas A, Souhait L, Swinburne IA, Obholzer ND, Megason SG. Interplay of cell shape and division orientation promotes robust morphogenesis of developing epithelia. Cell. 159: 415-27. PMID 25303534 DOI: 10.1016/j.cell.2014.09.007  0.72
2013 Mosaliganti KR, Gelas A, Megason SG. An efficient, scalable, and adaptable framework for solving generic systems of level-set PDEs. Frontiers in Neuroinformatics. 7: 35. PMID 24501592 DOI: 10.3389/fninf.2013.00035  0.72
2013 Xiong F, Tentner AR, Huang P, Gelas A, Mosaliganti KR, Souhait L, Rannou N, Swinburne IA, Obholzer ND, Cowgill PD, Schier AF, Megason SG. Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell. 153: 550-61. PMID 23622240 DOI: 10.1016/j.cell.2013.03.023  0.72
2013 Miller AC, Obholzer ND, Shah AN, Megason SG, Moens CB. RNA-seq-based mapping and candidate identification of mutations from forward genetic screens. Genome Research. 23: 679-86. PMID 23299976 DOI: 10.1101/gr.147322.112  0.72
2012 Mosaliganti KR, Noche RR, Xiong F, Swinburne IA, Megason SG. ACME: automated cell morphology extractor for comprehensive reconstruction of cell membranes. Plos Computational Biology. 8: e1002780. PMID 23236265 DOI: 10.1371/journal.pcbi.1002780  0.72
2012 Obholzer N, Swinburne IA, Schwab E, Nechiporuk AV, Nicolson T, Megason SG. Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing. Development (Cambridge, England). 139: 4280-90. PMID 23052906 DOI: 10.1242/dev.083931  0.72
2012 Shaheen R, Faqeih E, Shamseldin HE, Noche RR, Sunker A, Alshammari MJ, Al-Sheddi T, Adly N, Al-Dosari MS, Megason SG, Al-Husain M, Al-Mohanna F, Alkuraya FS. POC1A truncation mutation causes a ciliopathy in humans characterized by primordial dwarfism. American Journal of Human Genetics. 91: 330-6. PMID 22840364 DOI: 10.1016/j.ajhg.2012.05.025  0.72
2012 Huang P, Xiong F, Megason SG, Schier AF. Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord. Plos Genetics. 8: e1002762. PMID 22685423 DOI: 10.1371/journal.pgen.1002762  0.72
2012 Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental Cell. 22: 625-38. PMID 22421047 DOI: 10.1016/j.devcel.2012.01.003  0.72
2011 Trinh le A, Hochgreb T, Graham M, Wu D, Ruf-Zamojski F, Jayasena CS, Saxena A, Hawk R, Gonzalez-Serricchio A, Dixson A, Chow E, Gonzales C, Leung HY, Solomon I, Bronner-Fraser M, ... Megason SG, et al. A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes & Development. 25: 2306-20. PMID 22056673 DOI: 10.1101/gad.174037.111  0.72
2011 Megason SG, Srinivas S, Dickinson ME, Hadjantonakis AK. Microscopy to mechanism across the scales of development. Current Opinion in Genetics & Development. 21: 519-22. PMID 21996420 DOI: 10.1016/j.gde.2011.09.012  0.72
2011 Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, Silver PA. Towards a synthetic chloroplast. Plos One. 6: e18877. PMID 21533097 DOI: 10.1371/journal.pone.0018877  0.72
2011 Megason SG. Current challenges in image analysis for in toto imaging of zebrafish Proceedings - International Symposium On Biomedical Imaging. 1730-1732. DOI: 10.1109/ISBI.2011.5872739  0.72
2010 Mosaliganti K, Janoos F, Gelas A, Noche R, Obholzer N, Machiraju R, Megason SG. ANISOTROPIC PLATE DIFFUSION FILTERING FOR DETECTION OF CELL MEMBRANES IN 3D MICROSCOPY IMAGES. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 588-591. PMID 21766060 DOI: 10.1109/ISBI.2010.5490110  0.72
2009 Mosaliganti K, Gelas A, Gouaillard A, Megason SG. TISSUE LEVEL SEGMENTATION AND TRACKING OF BIOLOGICAL STRUCTURES IN MICROSCOPIC IMAGES BASED ON DENSITY MAPS. Proceedings / Ieee International Symposium On Biomedical Imaging: From Nano to Macro. Ieee International Symposium On Biomedical Imaging. 1354-1357. PMID 21766061 DOI: 10.1109/ISBI.2009.5193316  0.72
2009 Gelas A, Mosaliganti K, Gouaillard A, Souhait L, Noche R, Obholzer N, Megason SG. VARIATIONAL LEVEL-SET WITH GAUSSIAN SHAPE MODEL FOR CELL SEGMENTATION. Proceedings / Icip ... International Conference On Image Processing. 1089-1092. PMID 21738904 DOI: 10.1109/ICIP.2009.5413463  0.72
2009 Mosaliganti K, Gelas A, Gouaillard A, Noche R, Obholzer N, Megason S. Detection of spatially correlated objects in 3D images using appearance models and coupled active contours. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 12: 641-8. PMID 20426166 DOI: 10.1007/978-3-642-04271-3_78  0.72
2009 Gouaillard A, Mosaliganti K, Gelas A, Souhait L, Obholzer N, Megason S. Streaming level set algorithm for 3D segmentation of confocal microscopy images. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 3621-4. PMID 19964083 DOI: 10.1109/IEMBS.2009.5333522  0.72
2009 Megason SG. In toto imaging of embryogenesis with confocal time-lapse microscopy. Methods in Molecular Biology (Clifton, N.J.). 546: 317-32. PMID 19378112 DOI: 10.1007/978-1-60327-977-2_19  0.72
2008 Cedilnik A, Baumes J, Ibanez L, Megason S, Wylie B. Integration of information and volume visualization for analysis of cell lineage and gene expression during embryogenesis Proceedings of Spie - the International Society For Optical Engineering. 6809. DOI: 10.1117/12.768014  0.72
2008 Link BA, Megason SG. Zebrafish as a model for development Source Book of Models For Biomedical Research. 103-112. DOI: 10.1007/978-1-59745-285-4_13  0.72
2007 Megason SG, Fraser SE. Imaging in systems biology. Cell. 130: 784-95. PMID 17803903 DOI: 10.1016/j.cell.2007.08.031  0.72
2005 Megason S, Amsterdam A, Hopkins N, Lin S. Uses of GFP in transgenic vertebrates Methods of Biochemical Analysis. 47: 285-303. PMID 16335718 DOI: 10.1002/0471739499.ch13  0.72
2003 Megason SG, Fraser SE. Digitizing life at the level of the cell: high-performance laser-scanning microscopy and image analysis for in toto imaging of development. Mechanisms of Development. 120: 1407-20. PMID 14623446 DOI: 10.1016/j.mod.2003.07.005  0.72
2002 Megason SG, McMahon AP. A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development (Cambridge, England). 129: 2087-98. PMID 11959819  0.72
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