Charles L. Howe, Ph.D. - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
neurodegneration, Down syndrome

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

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Year Citation  Score
2015 Walker-Caulfield ME, Guo Y, Johnson RK, McCarthy CB, Fitz-Gibbon PD, Lucchinetti CF, Howe CL. NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG. Journal of Neuroinflammation. 12: 185. PMID 26423139 DOI: 10.1186/s12974-015-0403-8  0.92
2014 Howe CL, Kaptzan T, Magaña SM, Ayers-Ringler JR, Lafrance-Corey RG, Lucchinetti CF. Neuromyelitis optica IgG stimulates an immunological response in rat astrocyte cultures Glia. 62: 692-708. PMID 24492996 DOI: 10.1002/glia.22635  0.92
2013 Sauer BM, Schmalstieg WF, Howe CL. Axons are injured by antigen-specific CD8(+) T cells through a MHC class I- and granzyme B-dependent mechanism. Neurobiology of Disease. 59: 194-205. PMID 23899663 DOI: 10.1016/j.nbd.2013.07.010  0.92
2013 Poland GA, Poland CM, Howe CL. Influenza vaccine and Guillain-Barré syndrome: making informed decisions. Lancet (London, England). 381: 1437-9. PMID 23622271 DOI: 10.1016/S0140-6736(13)60182-8  0.92
2013 Bergstrom RA, Choi JH, Manduca A, Shin HS, Worrell GA, Howe CL. Automated identification of multiple seizure-related and interictal epileptiform event types in the EEG of mice. Scientific Reports. 3: 1483. PMID 23514826 DOI: 10.1038/srep01483  0.92
2012 Howe CL, Lafrance-Corey RG, Sundsbak RS, Sauer BM, Lafrance SJ, Buenz EJ, Schmalstieg WF. Hippocampal protection in mice with an attenuated inflammatory monocyte response to acute CNS picornavirus infection. Scientific Reports. 2: 545. PMID 22848791 DOI: 10.1038/srep00545  0.92
2012 Howe CL, Lafrance-Corey RG, Sundsbak RS, Lafrance SJ. Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain. Journal of Neuroinflammation. 9: 50. PMID 22405261 DOI: 10.1186/1742-2094-9-50  0.92
2011 LaFrance-Corey RG, Howe CL. Isolation of brain-infiltrating leukocytes. Journal of Visualized Experiments : Jove. PMID 21694694 DOI: 10.3791/2747  0.92
2011 German CL, Sauer BM, Howe CL. The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures. Experimental Cell Research. 317: 1955-69. PMID 21619877 DOI: 10.1016/j.yexcr.2011.05.009  0.92
2011 Rao AA, Ye H, Decker PA, Howe CL, Wetmore C. Therapeutic doses of cranial irradiation induce hippocampus-dependent cognitive deficits in young mice. Journal of Neuro-Oncology. 105: 191-8. PMID 21499912 DOI: 10.1007/s11060-011-0582-9  0.92
2011 Popescu BF, Lennon VA, Parisi JE, Howe CL, Weigand SD, Cabrera-Gómez JA, Newell K, Mandler RN, Pittock SJ, Weinshenker BG, Lucchinetti CF. Neuromyelitis optica unique area postrema lesions: nausea, vomiting, and pathogenic implications. Neurology. 76: 1229-37. PMID 21368286 DOI: 10.1212/WNL.0b013e318214332c  0.92
2010 Deb C, Lafrance-Corey RG, Schmalstieg WF, Sauer BM, Wang H, German CL, Windebank AJ, Rodriguez M, Howe CL. CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis. Plos One. 5: e12478. PMID 20814579 DOI: 10.1371/journal.pone.0012478  0.92
2010 Arneson LN, Upshaw JL, Howe CL, Felts SJ, Rodriguez M, Pease LR, Colonna M. Retraction: TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 6557. PMID 20483797 DOI: 10.4049/jimmunol.1090036  0.92
2010 Lacerda-Queiroz N, Rodrigues DH, Vilela MC, Miranda AS, Amaral DC, Camargos ER, Carvalho LJ, Howe CL, Teixeira MM, Teixeira AL. Inflammatory changes in the central nervous system are associated with behavioral impairment in Plasmodium berghei (strain ANKA)-infected mice. Experimental Parasitology. 125: 271-8. PMID 20138873 DOI: 10.1016/j.exppara.2010.02.002  0.92
2010 Blocki FA, Radhakrishnan S, Van Keulen VP, Heckman KL, Ciric B, Howe CL, Rodriguez M, Kwon E, Pease LR. Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC (The FASEB Journal (2006) 20, 13 (2408-2410) DOI: 10.1096/fj.06-6171fje) Faseb Journal. 24: 2135-2136. DOI: 10.1096/fj.06-6171fjeRET  0.92
2009 Deb C, Lafrance-Corey RG, Zoecklein L, Papke L, Rodriguez M, Howe CL. Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis. Journal of Neuropathology and Experimental Neurology. 68: 1037-48. PMID 19680139 DOI: 10.1097/NEN.0b013e3181b5417e  0.92
2009 German CL, Howe CL. Preparation of biologically active subcellular fractions using the Balch homogenizer. Analytical Biochemistry. 394: 117-24. PMID 19622341 DOI: 10.1016/j.ab.2009.07.024  0.92
2009 Buenz EJ, Sauer BM, Lafrance-Corey RG, Deb C, Denic A, German CL, Howe CL. Apoptosis of hippocampal pyramidal neurons is virus independent in a mouse model of acute neurovirulent picornavirus infection. The American Journal of Pathology. 175: 668-84. PMID 19608874 DOI: 10.2353/ajpath.2009.081126  0.92
2009 Deb C, Howe CL. Functional characterization of mouse spinal cord infiltrating CD8+ lymphocytes. Journal of Neuroimmunology. 214: 33-42. PMID 19596449 DOI: 10.1016/j.jneuroim.2009.06.013  0.92
2009 Rodriguez M, Zoecklein L, Papke L, Gamez J, Denic A, Macura S, Howe C. Tumor necrosis factor α is reparative via TNFR1 in the hippocampus and via TNFR2 in the striatum after virus-induced encephalitis Brain Pathology. 19: 12-26. PMID 18422761 DOI: 10.1111/j.1750-3639.2008.00151.x  0.92
2008 Radhakrishnan S, Arneson LN, Upshaw JL, Howe CL, Felts SJ, Colonna M, Leibson PJ, Rodriguez M, Pease LR. TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 7863-72. PMID 19017976  0.92
2008 Hinson SR, Roemer SF, Lucchinetti CF, Fryer JP, Kryzer TJ, Chamberlain JL, Howe CL, Pittock SJ, Lennon VA. Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2. The Journal of Experimental Medicine. 205: 2473-81. PMID 18838545 DOI: 10.1084/jem.20081241  0.92
2008 Deb C, Howe CL. NKG2D contributes to efficient clearance of picornavirus from the acutely infected murine brain. Journal of Neurovirology. 14: 261-6. PMID 18569460 DOI: 10.1080/13550280802105002  0.92
2008 Rodriguez M, Zoecklein L, Kerkvliet JG, Pavelko KD, Papke L, Howe CL, Pease LR, David C. Human HLA-DR transgenes protect mice from fatal virus-induced encephalomyelitis and chronic demyelination. Journal of Virology. 82: 3369-80. PMID 18234804 DOI: 10.1128/JVI.02243-07  0.92
2008 Kahraman A, Barreyro FJ, Bronk SF, Werneburg NW, Mott JL, Akazawa Y, Masuoka HC, Howe CL, Gores GJ. TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse. Hepatology (Baltimore, Md.). 47: 1317-30. PMID 18220275 DOI: 10.1002/hep.22136  0.92
2008 Howe CL. Immunological aspects of axon injury in multiple sclerosis. Current Topics in Microbiology and Immunology. 318: 93-131. PMID 18219816 DOI: 10.1007/978-3-540-73677-6-5  0.92
2007 Buenz EJ, Bauer BA, Schnepple DJ, Wahner-Roedler DL, Vandell AG, Howe CL. A randomized Phase I study of Atuna racemosa: a potential new anti-MRSA natural product extract. Journal of Ethnopharmacology. 114: 371-6. PMID 17889468 DOI: 10.1016/j.jep.2007.08.027  0.92
2007 Howe CL, Ure D, Adelson JD, LaFrance-Corey R, Johnson A, Rodriguez M. CD8+ T cells directed against a viral peptide contribute to loss of motor function by disrupting axonal transport in a viral model of fulminant demyelination. Journal of Neuroimmunology. 188: 13-21. PMID 17493690 DOI: 10.1016/j.jneuroim.2007.04.005  0.92
2007 Buenz EJ, Howe CL. Beta-methylamino-alanine (BMAA) injures hippocampal neurons in vivo. Neurotoxicology. 28: 702-4. PMID 17379313 DOI: 10.1016/j.neuro.2007.02.010  0.92
2007 Buenz EJ, Howe CL. Mechanisms of action of IVIG in adult onset Rasmussen's encephalitis. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 34: 108-9. PMID 17352358  0.92
2007 Buenz EJ, Limburg PJ, Howe CL. A high-throughput 3-parameter flow cytometry-based cell death assay. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 170-3. PMID 17226860 DOI: 10.1002/cyto.a.20376  0.92
2007 Howe CL, Adelson JD, Rodriguez M. Absence of perforin expression confers axonal protection despite demyelination. Neurobiology of Disease. 25: 354-9. PMID 17112732 DOI: 10.1016/j.nbd.2006.10.001  0.92
2007 Buenz EJ, Howe CL. Response to Buenz and Howe [2] Journal of Perinatology. 27: 197. DOI: 10.1038/sj.jp.7211661  0.92
2006 Buenz EJ, Bauer BA, Johnson HE, Tavana G, Beekman EM, Frank KL, Howe CL. Searching historical herbal texts for potential new drugs. Bmj (Clinical Research Ed.). 333: 1314-5. PMID 17185721 DOI: 10.1136/bmj.39008.492361.BE  0.92
2006 Howe CL. Coated glass and vicryl microfibers as artificial axons. Cells, Tissues, Organs. 183: 180-94. PMID 17159344 DOI: 10.1159/000096509  0.92
2006 Blocki FA, Radhakrishnan S, Van Keulen VP, Heckman KL, Ciric B, Howe CL, Rodriguez M, Kwon E, Pease LR. Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2408-10. PMID 17023390 DOI: 10.1096/fj.06-6171fje  0.92
2006 Buenz EJ, Rodriguez M, Howe CL. Disrupted spatial memory is a consequence of picornavirus infection. Neurobiology of Disease. 24: 266-73. PMID 16919964 DOI: 10.1016/j.nbd.2006.07.003  0.92
2006 Howe CL, Mayoral S, Rodriguez M. Activated microglia stimulate transcriptional changes in primary oligodendrocytes via IL-1beta. Neurobiology of Disease. 23: 731-9. PMID 16887357 DOI: 10.1016/j.nbd.2006.06.012  0.92
2006 Rodriguez M, Zoecklein L, Gamez JD, Pavelko KD, Papke LM, Nakane S, Howe C, Radhakrishnan S, Hansen MJ, David CS, Warrington AE, Pease LR. STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 343-5. PMID 16352646 DOI: 10.1096/fj.05-4650fje  0.92
2006 Buenz EJ, Howe CL. Picornaviruses and cell death. Trends in Microbiology. 14: 28-36. PMID 16337385 DOI: 10.1016/j.tim.2005.11.003  0.92
2005 Howe CL. Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk. Theoretical Biology & Medical Modelling. 2: 43. PMID 16236165 DOI: 10.1186/1742-4682-2-43  0.92
2005 Saxena S, Howe CL, Cosgaya JM, Steiner P, Hirling H, Chan JR, Weis J, Krüttgen A. Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking. Molecular and Cellular Neurosciences. 28: 571-87. PMID 15737746 DOI: 10.1016/j.mcn.2004.11.011  0.92
2005 Howe CL, Mobley WC. Long-distance retrograde neurotrophic signaling. Current Opinion in Neurobiology. 15: 40-8. PMID 15721743 DOI: 10.1016/j.conb.2005.01.010  0.92
2005 Howe CL, Rodriguez M. Remyelination as Neuroprotection Multiple Sclerosis as a Neuronal Disease. 389-419. DOI: 10.1016/B978-012738761-1/50028-6  0.92
2004 Saxena S, Howe CL, Cosgaya JM, Hu M, Weis J, Krüttgen A. Differences in the surface binding and endocytosis of neurotrophins by p75NTR. Molecular and Cellular Neurosciences. 26: 292-307. PMID 15207854 DOI: 10.1016/j.mcn.2004.02.006  0.92
2004 Howe CL, Bieber AJ, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiology of Disease. 15: 120-31. PMID 14751777 DOI: 10.1016/j.nbd.2003.09.002  0.92
2004 Howe CL, Mobley WC. Signaling endosome hypothesis: A cellular mechanism for long distance communication. Journal of Neurobiology. 58: 207-16. PMID 14704953 DOI: 10.1002/neu.10323  0.92
2004 Delcroix JD, Valletta J, Wu C, Howe CL, Lai CF, Cooper JD, Belichenko PV, Salehi A, Mobley WC. Trafficking the NGF signal: implications for normal and degenerating neurons. Progress in Brain Research. 146: 3-23. PMID 14699953  0.92
2003 Ciric B, Howe CL, Paz Soldan M, Warrington AE, Bieber AJ, Van Keulen V, Rodriguez M, Pease LR. Human monoclonal IgM antibody promotes CNS myelin repair independent of Fc function. Brain Pathology (Zurich, Switzerland). 13: 608-16. PMID 14655764  0.92
2003 Rodriguez M, Zoecklein LJ, Howe CL, Pavelko KD, Gamez JD, Nakane S, Papke LM. Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection. Journal of Virology. 77: 12252-65. PMID 14581562 DOI: 10.1128/JVI.77.22.12252-12265.2003  0.92
2003 Howe CL. Depolarization of PC12 cells induces neurite outgrowth and enhances nerve growth factor-induced neurite outgrowth in rats. Neuroscience Letters. 351: 41-5. PMID 14550909 DOI: 10.1016/S0304-3940(03)00915-7  0.92
2003 Pavelko KD, Howe CL, Drescher KM, Gamez JD, Johnson AJ, Wei T, Ransohoff RM, Rodriguez M. Interleukin-6 protects anterior horn neurons from lethal virus-induced injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 481-92. PMID 12533608  0.92
2003 Howe CL. A Cbl:clathrin complex involved in NGF signaling for neurite outgrowth Neuroscience Research Communications. 33: 86-98. DOI: 10.1002/nrc.10084  0.92
2002 Ransohoff RM, Howe CL, Rodriguez M. Growth factor treatment of demyelinating disease: at last, a leap into the light. Trends in Immunology. 23: 512-6. PMID 12401395 DOI: 10.1016/S1471-4906(02)02321-9  0.92
2001 Silver MA, Fagiolini M, Gillespie DC, Howe CL, Frank MG, Issa NP, Antonini A, Stryker MP. Infusion of nerve growth factor (NGF) into kitten visual cortex increases immunoreactivity for NGF, NGF receptors, and choline acetyltransferase in basal forebrain without affecting ocular dominance plasticity or column development. Neuroscience. 108: 569-85. PMID 11738495 DOI: 10.1016/S0306-4522(01)00391-8  0.92
2001 Howe CL, Valletta JS, Rusnak AS, Mobley WC. NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron. 32: 801-14. PMID 11738027 DOI: 10.1016/S0896-6273(01)00526-8  0.92
2001 Sofroniew MV, Howe CL, Mobley WC. Nerve growth factor signaling, neuroprotection, and neural repair. Annual Review of Neuroscience. 24: 1217-81. PMID 11520933 DOI: 10.1146/annurev.neuro.24.1.1217  0.92
2001 Cooper JD, Salehi A, Delcroix JD, Howe CL, Belichenko PV, Chua-Couzens J, Kilbridge JF, Carlson EJ, Epstein CJ, Mobley WC. Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proceedings of the National Academy of Sciences of the United States of America. 98: 10439-44. PMID 11504920 DOI: 10.1073/pnas.181219298  0.92
2000 Beattie EC, Howe CL, Wilde A, Brodsky FM, Mobley WC. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7325-33. PMID 11007890  0.92
1996 Beattie EC, Zhou J, Grimes ML, Bunnett NW, Howe CL, Mobley WC. A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration. Cold Spring Harbor Symposia On Quantitative Biology. 61: 389-406. PMID 9246468  0.92
1996 Yuen EC, Howe CL, Li Y, Holtzman DM, Mobley WC. Nerve growth factor and the neurotrophic factor hypothesis. Brain & Development. 18: 362-8. PMID 8891230 DOI: 10.1016/0387-7604(96)00051-4  0.92
1994 Rodriguez M, Prayoonwiwat N, Howe C, Sanborn K. Proteolipid protein gene expression in demyelination and remyelination of the central nervous system: A model for multiple sclerosis Journal of Neuropathology and Experimental Neurology. 53: 136-143. PMID 7509847 DOI: 10.1097/00005072-199403000-00004  0.92
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