| Year |
Citation |
Score |
| 2023 |
Park JU, Petassi MT, Hsieh SC, Mehrotra E, Schuler G, Budhathoki J, Truong VH, Thyme SB, Ke A, Kellogg EH, Peters JE. Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition. Molecular Cell. 83: 1827-1838.e6. PMID 37267904 DOI: 10.1016/j.molcel.2023.05.005 |
0.631 |
|
| 2020 |
Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, ... ... Thyme SB, et al. Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nature Methods. PMID 32483333 DOI: 10.1038/S41592-020-0848-2 |
0.409 |
|
| 2016 |
Thyme SB, Akhmetova L, Montague TG, Valen E, Schier AF. Internal guide RNA interactions interfere with Cas9-mediated cleavage. Nature Communications. 7: 11750. PMID 27282953 DOI: 10.1038/Ncomms11750 |
0.357 |
|
| 2016 |
Labun K, Montague TG, Gagnon JA, Thyme SB, Valen E. CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering. Nucleic Acids Research. PMID 27185894 DOI: 10.1093/Nar/Gkw398 |
0.465 |
|
| 2016 |
Thyme SB, Schier AF. Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Reports. PMID 27149851 DOI: 10.1016/J.Celrep.2016.03.072 |
0.332 |
|
| 2016 |
Thyme S, Song Y. Computational Design of DNA-Binding Proteins. Methods in Molecular Biology (Clifton, N.J.). 1414: 265-83. PMID 27094297 DOI: 10.1007/978-1-4939-3569-7_16 |
0.635 |
|
| 2014 |
Thyme SB, Song Y, Brunette TJ, Szeto MD, Kusak L, Bradley P, Baker D. Massively parallel determination and modeling of endonuclease substrate specificity. Nucleic Acids Research. 42: 13839-52. PMID 25389263 DOI: 10.1093/Nar/Gku1096 |
0.717 |
|
| 2014 |
Gagnon JA, Valen E, Thyme SB, Huang P, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. Plos One. 9: e98186. PMID 24873830 DOI: 10.1371/Journal.Pone.0098186 |
0.396 |
|
| 2014 |
Wang Y, Khan IF, Boissel S, Jarjour J, Pangallo J, Thyme S, Baker D, Scharenberg AM, Rawlings DJ. Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus. Nucleic Acids Research. 42: 6463-75. PMID 24682825 DOI: 10.1093/Nar/Gku224 |
0.759 |
|
| 2014 |
Thyme S, Baker D. Redesigning the specificity of protein-DNA interactions with rosetta Methods in Molecular Biology. 1123: 265-282. PMID 24510272 DOI: 10.1007/978-1-62703-968-0_17 |
0.601 |
|
| 2014 |
Thyme SB, Boissel SJ, Arshiya Quadri S, Nolan T, Baker DA, Park RU, Kusak L, Ashworth J, Baker D. Reprogramming homing endonuclease specificity through computational design and directed evolution. Nucleic Acids Research. 42: 2564-76. PMID 24270794 DOI: 10.1093/Nar/Gkt1212 |
0.742 |
|
| 2012 |
Thyme SB, Baker D, Bradley P. Improved modeling of side-chain--base interactions and plasticity in protein--DNA interface design. Journal of Molecular Biology. 419: 255-74. PMID 22426128 DOI: 10.1016/J.Jmb.2012.03.005 |
0.66 |
|
| 2011 |
Szeto MD, Boissel SJ, Baker D, Thyme SB. Mining endonuclease cleavage determinants in genomic sequence data. The Journal of Biological Chemistry. 286: 32617-27. PMID 21778233 DOI: 10.1074/Jbc.M111.259572 |
0.74 |
|
| 2011 |
Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY, Hovde BT, Baker D, Monnat RJ, Burt A, Crisanti A. A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature. 473: 212-5. PMID 21508956 DOI: 10.1038/Nature09937 |
0.425 |
|
| 2009 |
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D. Exploitation of binding energy for catalysis and design. Nature. 461: 1300-4. PMID 19865174 DOI: 10.1038/Nature08508 |
0.715 |
|
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