Huanghe Yang, Ph.D. - Publications

Affiliations: 
2015- Biochemistry Duke Medical School, Durham, NC, United States 
Area:
Ion channels, biophysics, electrophysiology, neuroscience

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Le T, Le SC, Zhang Y, Liang P, Yang H. Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F. The Journal of Biological Chemistry. PMID 32709749 DOI: 10.1074/jbc.AC120.014872  0.36
2020 Liao C, Zhang Y, Fan C, Herring LE, Liu J, Locasale JW, Takada M, Zhou J, Zurlo G, Hu L, Simon JM, Ptacek TS, Andrianov VG, Loza E, Peng Y, ... Yang H, et al. Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer. Cancer Discovery. PMID 32690540 DOI: 10.1158/2159-8290.Cd-20-0288  0.8
2020 Zhang G, Gibson RA, McDonald M, Liang P, Kang PW, Shi J, Yang H, Cui J, Mikati MA. A Gain-of-Function Mutation in KCNMA1 Causes Dystonia Spells Controlled With Stimulant Therapy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32633875 DOI: 10.1002/mds.28138  0.84
2020 Zhang Y, Le T, Grabau R, Mohseni Z, Kim H, Natale DR, Feng L, Pan H, Yang H. TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development. Science Advances. 6: eaba0310. PMID 32494719 DOI: 10.1126/Sciadv.Aba0310  0.36
2020 Jia Z, Liang P, Le T, Yang H, Chen J. The Road not Taken - Lipid/Ion Conduction Pathways in TMEM16 Protein Family Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1542  0.36
2019 Zhang Y, Yang H. Corrigendum to "A simple and robust fluorescent labeling method to quantify trophoblast fusion" [Placenta 77 (2019) 16-18]. Placenta. PMID 31130263 DOI: 10.1016/j.placenta.2019.05.011  0.36
2019 Le T, Jia Z, Le SC, Zhang Y, Chen J, Yang H. An inner activation gate controls TMEM16F phospholipid scrambling. Nature Communications. 10: 1846. PMID 31015464 DOI: 10.1038/S41467-019-09778-7  0.36
2019 Zhang Y, Yang H. A simple and robust fluorescent labeling method to quantify trophoblast fusion. Placenta. 77: 16-18. PMID 30827351 DOI: 10.1016/j.placenta.2019.01.016  0.36
2019 Le T, Le SC, Yang H. Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids. The Journal of Biological Chemistry. PMID 30700552 DOI: 10.1074/jbc.AC118.006530  0.36
2018 Zubcevic L, Le S, Yang H, Lee SY. Conformational plasticity in the selectivity filter of the TRPV2 ion channel. Nature Structural & Molecular Biology. 25: 405-415. PMID 29728656 DOI: 10.2210/Pdb6Bwj/Pdb  0.36
2017 Zhou Y, Yang H, Cui J, Lingle CJ. Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel. The Journal of General Physiology. PMID 29025867 DOI: 10.1085/jgp.201711845  0.84
2017 Zhang Y, Zhang Z, Xiao S, Tien J, Le S, Le T, Jan LY, Yang H. Inferior Olivary TMEM16B Mediates Cerebellar Motor Learning. Neuron. 95: 1103-1111.e4. PMID 28858616 DOI: 10.1016/J.Bpj.2017.11.752  0.92
2016 Dong Y, Wang Q, Wu H, Chen Y, Lu CH, Chi Y, Yang HH. Graphitic Carbon Nitride Materials: Sensing, Imaging and Therapy. Small (Weinheim An Der Bergstrasse, Germany). PMID 27611869 DOI: 10.1002/smll.201602056  0.4
2016 Yang H, Wang Y, Chen X, Zhao X, Gu L, Huang H, Yan J, Xu C, Li G, Wu J, Edwards AJ, Dittrich B, Tang Z, Wang D, Lehtovaara L, et al. Plasmonic twinned silver nanoparticles with molecular precision. Nature Communications. 7: 12809. PMID 27611564 DOI: 10.1038/Ncomms12809  0.36
2016 Pan H, Yu H, Ravi V, Li C, Lee AP, Lian MM, Tay BH, Brenner S, Wang J, Yang H, Zhang G, Venkatesh B. The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate. Gigascience. 5: 36. PMID 27609345 DOI: 10.1186/S13742-016-0144-3  0.64
2016 Wang Z, Ju J, Yang J, Ma Z, Liu D, Cui K, Yang H, Chang J, Huang N, Li L. The non-equilibrium phase diagrams of flow-induced crystallization and melting of polyethylene. Scientific Reports. 6: 32968. PMID 27609305 DOI: 10.1038/srep32968  0.64
2016 Wang Y, Wang H, Pan T, Li L, Li J, Yang H. Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells. Oncotarget. PMID 27608840 DOI: 10.18632/oncotarget.11842  0.36
2016 Li S, Yang H, Guo Y, Wei F, Yang X, Li D, Li M, Xu W, Li W, Sun L, Gao Y, Wang Y. Comparative efficacy and safety of urate-lowering therapy for the treatment of hyperuricemia: a systematic review and network meta-analysis. Scientific Reports. 6: 33082. PMID 27605442 DOI: 10.1038/srep33082  0.56
2016 Sun W, Quan N, Wang L, Yang H, Chu D, Liu Q, Zhao X, Leng J, Li J. Cardiac-Specific Deletion of the Pdha1 Gene Sensitizes Heart to Toxicological Actions of Ischemic Stress. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27605416 DOI: 10.1093/toxsci/kfw154  0.36
2016 Yang H, Flower RJ, Huang X. Fellowships: Brexit threatens China collaboration. Nature. 537: 167. PMID 27604941 DOI: 10.1038/537167c  0.44
2016 Deng Z, Yang H, Liu Q, Wang Z, Feng T, Ouyang Y, Jin T, Ren H. Identification of novel susceptibility markers for the risk of overall breast cancer as well as subtypes defined by hormone receptor status in the Chinese population. Journal of Human Genetics. PMID 27604554 DOI: 10.1038/jhg.2016.97  0.36
2016 Guan X, Ma F, Liu S, Wu S, Xiao R, Yuan L, Sun X, Yi Z, Yang H, Xu B. Analysis of the hormone receptor status of circulating tumor cell subpopulations based on epithelial-mesenchymal transition: a proof-of-principle study on the heterogeneity of circulating tumor cells. Oncotarget. PMID 27602758 DOI: 10.18632/oncotarget.11787  0.52
2016 Weng X, Yang H, Xu J, Li X, Liao Q, Wang J. In vivo testing of porous Ti-25Nb alloy serving as a femoral stem prosthesis in a rabbit model. Experimental and Therapeutic Medicine. 12: 1323-1330. PMID 27602063 DOI: 10.3892/etm.2016.3472  0.48
2016 Wu JT, Wang SL, Chu YJ, Long DY, Dong JZ, Fan XW, Yang HT, Duan HY, Yan LJ, Qian P, Yang CK. Usefulness of a Combination of Interatrial Block and a High CHADS2 Score to Predict New Onset Atrial Fibrillation. International Heart Journal. PMID 27593538 DOI: 10.1536/ihj.15-505  0.36
2016 Wong WK, Su TW, Cheng WL, Yang HT, Wei WC, Ko PJ. Endovascular Stent Graft Repair is an Effective and Safe Alternative Therapy for Arteriovenous Graft Pseudoaneurysms. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society For Vascular Surgery. PMID 27592733 DOI: 10.1016/j.ejvs.2016.07.019  0.32
2016 Jiang Q, Zhou Y, Yang H, Li L, Deng X, Cheng C, Xie Y, Luo X, Fang W, Liu Z. A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma. Oncotarget. PMID 27589832 DOI: 10.18632/oncotarget.11691  0.48
2016 Niu L, Zhang Y, Li Q, Dai J, Yin H, Duan L, Yang H, Liang W, Qin Z, Zhang J, Pan Y. The analysis of correlative factors affecting long-term outcomes in patients with Solid Cerebellar Hemangioblastomas. Clinical Neurology and Neurosurgery. 150: 59-66. PMID 27588372 DOI: 10.1016/j.clineuro.2016.08.028  0.36
2016 Yao J, Wang XQ, Li YJ, Shan K, Yang H, Wang YN, Yao MD, Liu C, Li XM, Shen Y, Liu JY, Cheng H, Yuan J, Zhang YY, Jiang Q, et al. Long non-coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling. Embo Molecular Medicine. 8: 1113. PMID 27587362 DOI: 10.15252/emmm.201606749  0.32
2016 Fang Z, Zhang S, Wang Y, Shen S, Wang F, Hao Y, Li Y, Zhang B, Zhou Y, Yang H. Long non-coding RNA MALAT-1 modulates metastatic potential of tongue squamous cell carcinomas partially through the regulation of small proline rich proteins. Bmc Cancer. 16: 706. PMID 27586393 DOI: 10.1186/s12885-016-2735-x  0.48
2016 Liu Y, Lin J, Zhang M, Chen K, Yang S, Wang Q, Yang H, Xie S, Zhou Y, Zhang X, Chen F, Yang Y. PINK1 is required for timely cell-type specific mitochondrial clearance during Drosophila midgut metamorphosis. Developmental Biology. PMID 27575041 DOI: 10.1016/j.ydbio.2016.08.028  0.48
2016 Liu N, Wang Z, Cheng Y, Zhang P, Wang X, Yang H, Liu H, Zhang Y, Tu Y. Acylglycerol kinase functions as an oncogene and an unfavorable prognostic marker of human gliomas. Human Pathology. PMID 27574811 DOI: 10.1016/j.humpath.2016.07.034  0.36
2016 Wang MS, Yang HC, Otecko NO, Wu DD, Zhang YP. Olfactory genes in Tibetan wild boar. Nature Genetics. 48: 972-3. PMID 27573682 DOI: 10.1038/ng.3631  0.32
2015 Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, et al. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nature Neuroscience. PMID 26258683 DOI: 10.1038/Nn.4088  0.92
2015 Yang H, Zhang G, Cui J. BK channels: multiple sensors, one activation gate. Frontiers in Physiology. 6: 29. PMID 25705194 DOI: 10.3389/fphys.2015.00029  0.92
2014 Zhang G, Yang H, Liang H, Yang J, Shi J, McFarland K, Chen Y, Cui J. A charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12280-8. PMID 25209270 DOI: 10.1523/Jneurosci.1174-14.2014  0.4
2014 Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 3. PMID 24980701 DOI: 10.7554/Elife.02772  0.92
2014 Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nature Medicine. 20: 624-32. PMID 24836577 DOI: 10.1038/Nm.3543  0.92
2014 Tien J, Peters CJ, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. Author response: A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity Elife. DOI: 10.7554/Elife.02772.012  0.92
2013 Sun X, Shi J, Delaloye K, Yang X, Yang H, Zhang G, Cui J. The interface between membrane-spanning and cytosolic domains in Ca²+-dependent K+ channels is involved in β subunit modulation of gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11253-61. PMID 23825428 DOI: 10.1523/JNEUROSCI.0620-13.2013  0.92
2013 Yang J, Yang H, Sun X, Delaloye K, Yang X, Moller A, Shi J, Cui J. Interaction between residues in the Mg2+-binding site regulates BK channel activation. The Journal of General Physiology. 141: 217-28. PMID 23359284 DOI: 10.1085/Jgp.201210794  0.92
2012 Yang H, Kim A, David T, Palmer D, Jin T, Tien J, Huang F, Cheng T, Coughlin SR, Jan YN, Jan LY. TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. Cell. 151: 111-22. PMID 23021219 DOI: 10.1016/J.Bpj.2012.11.2033  0.92
2012 Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, et al. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proceedings of the National Academy of Sciences of the United States of America. 109: 16354-9. PMID 22988107 DOI: 10.1073/Pnas.1214596109  0.92
2012 Berg J, Yang H, Jan LY. Ca2+-activated Cl- channels at a glance. Journal of Cell Science. 125: 1367-71. PMID 22526416 DOI: 10.1242/jcs.093260  0.92
2010 Yang J, Krishnamoorthy G, Saxena A, Zhang G, Shi J, Yang H, Delaloye K, Sept D, Cui J. An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing. Neuron. 66: 871-83. PMID 20620873 DOI: 10.1016/J.Neuron.2010.05.009  0.92
2009 Cui J, Yang H, Lee US. Molecular mechanisms of BK channel activation. Cellular and Molecular Life Sciences : Cmls. 66: 852-75. PMID 19099186 DOI: 10.1007/S00018-008-8609-X  0.92
2008 Yang H, Shi J, Zhang G, Yang J, Delaloye K, Cui J. Activation of Slo1 BK channels by Mg2+ coordinated between the voltage sensor and RCK1 domains. Nature Structural & Molecular Biology. 15: 1152-9. PMID 18931675 DOI: 10.1038/Nsmb.1507  0.92
2008 Yang H, Zhang G, Shi J, Lee US, Delaloye K, Cui J. Subunit-specific effect of the voltage sensor domain on Ca2+ sensitivity of BK channels. Biophysical Journal. 94: 4678-87. PMID 18339745 DOI: 10.1529/Biophysj.107.121590  0.92
2007 Yang H, Hu L, Shi J, Delaloye K, Horrigan FT, Cui J. Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channels. Proceedings of the National Academy of Sciences of the United States of America. 104: 18270-5. PMID 17984060 DOI: 10.1073/pnas.0705873104  0.92
2006 Yang H, Hu L, Shi J, Cui J. Tuning magnesium sensitivity of BK channels by mutations. Biophysical Journal. 91: 2892-900. PMID 16877509 DOI: 10.1529/biophysj.106.090159  0.92
2006 Hu L, Yang H, Shi J, Cui J. Effects of multiple metal binding sites on calcium and magnesium-dependent activation of BK channels. The Journal of General Physiology. 127: 35-49. PMID 16344323 DOI: 10.1085/jgp.200509317  0.92
2005 Du W, Bautista JF, Yang H, Diez-Sampedro A, You SA, Wang L, Kotagal P, Lüders HO, Shi J, Cui J, Richerson GB, Wang QK. Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder. Nature Genetics. 37: 733-8. PMID 15937479 DOI: 10.1038/Ng1585  0.92
2002 Tang J, Zhang T, Liang D, Yang H, Li N, Lin L. Direct decomposition of NO by microwave heating over Fe/NaZSM-5 Applied Catalysis B: Environmental. 36: 1-7. DOI: 10.1016/S0926-3373(01)00268-5  0.92
2001 Yang H, Zhang T, Tian H, Tang J, Xu D, Yang W, Lin L. Effect of Sr substitution on catalytic activity of La1-xSrxMnO3 (0≤x≤0.8) perovskite-type oxides for catalytic decomposition of hydrogen peroxide Reaction Kinetics and Catalysis Letters. 73: 311-316. DOI: 10.1023/A:1014115508872  0.92
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