Nicholas Gaiano - Publications

Johns Hopkins University, Baltimore, MD 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Yamanishi E, Yoon K, Alberi L, Gaiano N, Mizutani K. NF-κB signaling regulates the generation of intermediate progenitors in the developing neocortex. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 20: 706-19. PMID 26243725 DOI: 10.1111/gtc.12267  1
2015 Liu S, Wang Y, Worley PF, Mattson MP, Gaiano N. The canonical Notch pathway effector RBP-J regulates neuronal plasticity and expression of GABA transporters in hippocampal networks. Hippocampus. 25: 670-8. PMID 25515406 DOI: 10.1002/Hipo.22402  1
2012 Gaiano N, Alberi L, Liu S. Expression of notch proteins in pyramidal neurons in vivo. The Journal of Biological Chemistry. 287: 24595; author reply . PMID 22798548 DOI: 10.1074/Jbc.L112.379016  1
2012 Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, et al. Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer. Cancer Cell. 21: 626-41. PMID 22624713 DOI: 10.1016/J.Ccr.2012.03.041  1
2012 Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL. Botch promotes neurogenesis by antagonizing Notch. Developmental Cell. 22: 707-20. PMID 22445366 DOI: 10.1016/J.Devcel.2012.02.011  1
2012 Gaiano N. Mind's why Scientific American. 307: 3.  1
2011 Kim Y, Sharov AA, McDole K, Cheng M, Hao H, Fan CM, Gaiano N, Ko MS, Zheng Y. Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells. Science (New York, N.Y.). 334: 1706-10. PMID 22116031 DOI: 10.1126/Science.1211222  1
2011 Kim J, Oh WJ, Gaiano N, Yoshida Y, Gu C. Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism. Genes & Development. 25: 1399-411. PMID 21724832 DOI: 10.1101/Gad.2042011  1
2011 Pierfelice T, Alberi L, Gaiano N. Notch in the vertebrate nervous system: an old dog with new tricks. Neuron. 69: 840-55. PMID 21382546 DOI: 10.1016/J.Neuron.2011.02.031  1
2011 Alberi L, Liu S, Wang Y, Badie R, Smith-Hicks C, Wu J, Pierfelice TJ, Abazyan B, Mattson MP, Kuhl D, Pletnikov M, Worley PF, Gaiano N. Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron. 69: 437-44. PMID 21315255 DOI: 10.1016/J.Neuron.2011.01.004  1
2011 Pierfelice TJ, Schreck KC, Dang L, Asnaghi L, Gaiano N, Eberhart CG. Notch3 activation promotes invasive glioma formation in a tissue site-specific manner. Cancer Research. 71: 1115-25. PMID 21245095 DOI: 10.1158/0008-5472.Can-10-0690  1
2011 Yang MS, Hong JS, Kim ST, Lee KY, Park KW, Kwon ST, Kweon DH, Koh YH, Gaiano N, Yoon K. Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells. Biochemical and Biophysical Research Communications. 404: 133-8. PMID 21108929 DOI: 10.1016/j.bbrc.2010.11.080  1
2011 Russell JL, Goetsch SC, Gaiano NR, Hill JA, Olson EN, Schneider JW. A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circulation Research. 108: 51-9. PMID 21106942 DOI: 10.1161/Circresaha.110.233262  1
2010 Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 6060-70. PMID 21169257 DOI: 10.1158/1078-0432.Ccr-10-1624  1
2010 Pierfelice TJ, Gaiano N. Ultrasound-guided microinjection into the mouse forebrain in utero at E9.5. Journal of Visualized Experiments : Jove. PMID 21113114 DOI: 10.3791/2047  1
2010 Albéri L, Chi Z, Kadam SD, Mulholland JD, Dawson VL, Gaiano N, Comi AM. Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injury. Stroke; a Journal of Cerebral Circulation. 41: S64-71. PMID 20876509 DOI: 10.1161/Strokeaha.110.595298  1
2010 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ. The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nature Neuroscience. 13: 551-8. PMID 20364144 DOI: 10.1038/Nn.2527  1
2010 Claus EB, Abdel-Wahab M, Burger PC, Engelhard HH, Ellison DW, Gaiano N, Gutmann DH, Heck DA, Holland EC, Jallo GI, Kruchko C, Kun LE, Maria BL, Rumboldt Z, Seminara D, et al. Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop. Journal of Neurosurgery. Spine. 12: 117-21. PMID 20121344 DOI: 10.3171/2009.7.Spine09137  1
2010 Schreck KC, Taylor P, Bar EE, Gopalakrishnan V, Gaiano N, Eberhart CG. Abstract 14: Targeting Notch in malignant brain tumors: Crosstalk with Hedgehog as a potential mechanism of treatment resistance Cancer Research. 70: 14-14. DOI: 10.1158/1538-7445.Am10-14  0.92
2009 Sockanathan S, Gaiano N. Preview. Meninges Play a RAdical Role in Embryonic Neural Stem Cell Regulation. Cell Stem Cell. 5: 455-6. PMID 19896433 DOI: 10.1016/J.Stem.2009.10.010  1
2009 Schreck KC, Gaiano N. PML: a tumor suppressor essential for neocortical development. Nature Neuroscience. 12: 108-10. PMID 19172164 DOI: 10.1038/Nn0209-108  1
2008 Pierfelice TJ, Schreck KC, Eberhart CG, Gaiano N. Notch, neural stem cells, and brain tumors. Cold Spring Harbor Symposia On Quantitative Biology. 73: 367-75. PMID 19022772 DOI: 10.1101/Sqb.2008.73.013  1
2008 Gaiano N. Strange bedfellows: Reelin and Notch signaling interact to regulate cell migration in the developing neocortex. Neuron. 60: 189-91. PMID 18957210 DOI: 10.1016/j.neuron.2008.10.009  1
2008 Corbin JG, Gaiano N, Juliano SL, Poluch S, Stancik E, Haydar TF. Regulation of neural progenitor cell development in the nervous system. Journal of Neurochemistry. 106: 2272-87. PMID 18819190 DOI: 10.1111/J.1471-4159.2008.05522.X  1
2008 Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L. Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell. 2: 461-71. PMID 18462696 DOI: 10.1016/J.Stem.2008.03.001  1
2008 Ever L, Zhao RJ, Eswarakumar VP, Gaiano N. Fibroblast growth factor receptor 2 plays an essential role in telencephalic progenitors. Developmental Neuroscience. 30: 306-18. PMID 18073459 DOI: 10.1159/000112521  1
2007 Wu M, Kwon HY, Rattis F, Blum J, Zhao C, Ashkenazi R, Jackson TL, Gaiano N, Oliver T, Reya T. Imaging hematopoietic precursor division in real time. Cell Stem Cell. 1: 541-54. PMID 18345353 DOI: 10.1016/J.Stem.2007.08.009  1
2007 Mizutani K, Yoon K, Dang L, Tokunaga A, Gaiano N. Differential Notch signalling distinguishes neural stem cells from intermediate progenitors. Nature. 449: 351-5. PMID 17721509 DOI: 10.1038/Nature06090  1
2007 Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 445: 776-80. PMID 17259973 DOI: 10.1038/Nature05571  1
2006 Mizutani K, Gaiano N. Chalk one up for 'nature' during neocortical neurogenesis. Nature Neuroscience. 9: 717-8. PMID 16732198 DOI: 10.1038/nn0606-717  1
2006 Dang L, Yoon K, Wang M, Gaiano N. Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon. Developmental Neuroscience. 28: 58-69. PMID 16508304 DOI: 10.1159/000090753  1
2006 Dang L, Fan X, Chaudhry A, Wang M, Gaiano N, Eberhart CG. Notch3 signaling initiates choroid plexus tumor formation. Oncogene. 25: 487-91. PMID 16186803 DOI: 10.1038/Sj.Onc.1209074  1
2005 Yoon K, Gaiano N. Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nature Neuroscience. 8: 709-15. PMID 15917835 DOI: 10.1038/nn1475  1
2005 Ever L, Gaiano N. Radial 'glial' progenitors: neurogenesis and signaling. Current Opinion in Neurobiology. 15: 29-33. PMID 15721741 DOI: 10.1016/j.conb.2005.01.005  1
2005 Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nature Immunology. 6: 314-22. PMID 15665828 DOI: 10.1038/Ni1164  1
2004 Yoon K, Nery S, Rutlin ML, Radtke F, Fishell G, Gaiano N. Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9497-506. PMID 15509736 DOI: 10.1523/JNEUROSCI.0993-04.2004  1
2003 Corbin JG, Rutlin M, Gaiano N, Fishell G. Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development (Cambridge, England). 130: 4895-906. PMID 12930780 DOI: 10.1242/dev.00717  1
2002 Rallu M, Machold R, Gaiano N, Corbin JG, McMahon AP, Fishell G. Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development (Cambridge, England). 129: 4963-74. PMID 12397105  1
2002 Gaiano N, Fishell G. The role of notch in promoting glial and neural stem cell fates. Annual Review of Neuroscience. 25: 471-90. PMID 12052917 DOI: 10.1146/annurev.neuro.25.030702.130823  1
2001 Kohtz JD, Lee HY, Gaiano N, Segal J, Ng E, Larson T, Baker DP, Garber EA, Williams KP, Fishell G. N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons. Development (Cambridge, England). 128: 2351-63. PMID 11493554  1
2001 Lee JD, Kraus P, Gaiano N, Nery S, Kohtz J, Fishell G, Loomis CA, Treisman JE. An acylatable residue of Hedgehog is differentially required in Drosophila and mouse limb development. Developmental Biology. 233: 122-36. PMID 11319862 DOI: 10.1006/Dbio.2001.0218  1
2001 Chambers CB, Peng Y, Nguyen H, Gaiano N, Fishell G, Nye JS. Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors. Development (Cambridge, England). 128: 689-702. PMID 11171394  1
2000 Corbin JG, Gaiano N, Machold RP, Langston A, Fishell G. The Gsh2 homeodomain gene controls multiple aspects of telencephalic development. Development (Cambridge, England). 127: 5007-20. PMID 11060228  1
2000 Gaiano N, Nye JS, Fishell G. Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron. 26: 395-404. PMID 10839358 DOI: 10.1016/S0896-6273(00)81172-1  1
1999 Gaiano N, Kohtz JD, Turnbull DH, Fishell G. A method for rapid gain-of-function studies in the mouse embryonic nervous system. Nature Neuroscience. 2: 812-9. PMID 10461220 DOI: 10.1038/12186  1
1998 Gaiano N, Fishell G. Transplantation as a tool to study progenitors within the vertebrate nervous system. Journal of Neurobiology. 36: 152-61. PMID 9712301 DOI: 10.1002/(SICI)1097-4695(199808)36:2<152::AID-NEU4>3.0.CO;2-0  1
1997 Amsterdam A, Yoon C, Allende M, Becker T, Kawakami K, Burgess S, Gaiano N, Hopkins N. Retrovirus-mediated insertional mutagenesis in zebrafish and identification of a molecular marker for embryonic germ cells. Cold Spring Harbor Symposia On Quantitative Biology. 62: 437-50. PMID 9598379 DOI: 10.1101/Sqb.1997.062.01.052  1
1996 Allende ML, Amsterdam A, Becker T, Kawakami K, Gaiano N, Hopkins N. Insertional mutagenesis in zebrafish identifies two novel genes, pescadillo and dead eye, essential for embryonic development. Genes & Development. 10: 3141-55. PMID 8985183 DOI: 10.1101/Gad.10.24.3141  1
1996 Gaiano N, Amsterdam A, Kawakami K, Allende M, Becker T, Hopkins N. Insertional mutagenesis and rapid cloning of essential genes in zebrafish. Nature. 383: 829-32. PMID 8893009 DOI: 10.1038/383829A0  1
1996 Gaiano N, Hopkins N. Introducing genes into zebrafish. Biochimica Et Biophysica Acta. 1288: O11-4. PMID 8764844 DOI: 10.1016/0304-419X(96)00017-0  1
1996 Gaiano N, Allende M, Amsterdam A, Kawakami K, Hopkins N. Highly efficient germ-line transmission of proviral insertions in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 93: 7777-82. PMID 8755552 DOI: 10.1073/Pnas.93.15.7777  1
1994 Lin S, Gaiano N, Culp P, Burns JC, Friedmann T, Yee JK, Hopkins N. Integration and germ-line transmission of a pseudotyped retroviral vector in zebrafish. Science (New York, N.Y.). 265: 666-9. PMID 8036514 DOI: 10.1126/Science.8036514  1
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