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Michael A. Mandell, Ph.D. - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Microbiology & Microbial Pathogenesis) Washington University, Saint Louis, St. Louis, MO 
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Mandell MA, Beatty WL, Beverley SM. Quantitative single-cell analysis of Leishmania major amastigote differentiation demonstrates variably extended expression of the lipophosphoglycan (LPG) virulence factor in different host cell types. Plos Neglected Tropical Diseases. 16: e0010893. PMID 36302046 DOI: 10.1371/journal.pntd.0010893  0.512
2020 Saha B, Chisholm D, Kell AM, Mandell MA. A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α. Plos Pathogens. 16: e1009017. PMID 33052966 DOI: 10.1371/journal.ppat.1009017  0.304
2020 Mandell MA, Saha B, Thompson TA. The Tripartite Nexus: Autophagy, Cancer, and Tripartite Motif-Containing Protein Family Members. Frontiers in Pharmacology. 11: 308. PMID 32226386 DOI: 10.3389/Fphar.2020.00308  0.324
2019 Zhang X, Wu D, Wang C, Luo Y, Ding X, Yang X, Silva F, Arenas S, Weaver JM, Mandell M, Deretic V, Liu M. Sustained Activation of Autophagy Suppresses Adipocyte Maturation via a Lipolysis-dependent Mechanism. Autophagy. PMID 31840569 DOI: 10.1080/15548627.2019.1703355  0.31
2017 Mandell MA, Beverley SM. Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096392 DOI: 10.1073/Pnas.1619265114  0.571
2016 Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd MH, Kimura T, Choi SW, Peters R, Mandell M, Bruun JA, Johansen T, Deretic V. TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis. Developmental Cell. PMID 27693506 DOI: 10.1016/J.Devcel.2016.08.003  0.387
2016 Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V. TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. Journal of Cell Science. PMID 27562068 DOI: 10.1242/Jcs.190017  0.389
2016 Mandell MA, Beverley SM. Concomitant Immunity Induced by Persistent Leishmania major Does Not Preclude Secondary Re-Infection: Implications for Genetic Exchange, Diversity and Vaccination. Plos Neglected Tropical Diseases. 10: e0004811. PMID 27352043 DOI: 10.1371/Journal.Pntd.0004811  0.533
2016 Kimura T, Jain A, Choi SW, Mandell MA, Johansen T, Deretic V. TRIM-Directed Selective Autophagy Regulates Immune Activation. Autophagy. 0. PMID 26983397 DOI: 10.1080/15548627.2016.1154254  0.42
2016 Kimura T, Mandell M, Deretic V. Precision autophagy directed by receptor regulators - emerging examples within the TRIM family. Journal of Cell Science. 129: 881-91. PMID 26906420 DOI: 10.1242/Jcs.163758  0.352
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Mandell MA, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.352
2015 Chauhan S, Ahmed Z, Bradfute SB, Arko-Mensah J, Mandell MA, Won Choi S, Kimura T, Blanchet F, Waller A, Mudd MH, Jiang S, Sklar L, Timmins GS, Maphis N, Bhaskar K, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nature Communications. 6: 8620. PMID 26503418 DOI: 10.1038/Ncomms9620  0.356
2015 Kimura T, Jain A, Choi SW, Mandell MA, Schroder K, Johansen T, Deretic V. TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. The Journal of Cell Biology. PMID 26347139 DOI: 10.1083/Jcb.201503023  0.439
2015 Chauhan S, Mandell MA, Deretic V. Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy. Autophagy. 0. PMID 26313894 DOI: 10.1080/15548627.2015.1084457  0.38
2015 Chauhan S, Mandell MA, Deretic V. IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense. Molecular Cell. 58: 507-21. PMID 25891078 DOI: 10.1016/J.Molcel.2015.03.020  0.347
2015 Deretic V, Kimura T, Timmins G, Moseley P, Chauhan S, Mandell M. Immunologic manifestations of autophagy. The Journal of Clinical Investigation. 125: 75-84. PMID 25654553 DOI: 10.1172/Jci73945  0.434
2014 Mandell MA, Kimura T, Jain A, Johansen T, Deretic V. TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction. Autophagy. 10: 2387-8. PMID 25587751 DOI: 10.4161/15548627.2014.984278  0.385
2014 Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V. TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Developmental Cell. 30: 394-409. PMID 25127057 DOI: 10.1016/J.Devcel.2014.06.013  0.415
2013 Bradfute SB, Castillo EF, Arko-Mensah J, Chauhan S, Jiang S, Mandell M, Deretic V. Autophagy as an immune effector against tuberculosis. Current Opinion in Microbiology. 16: 355-65. PMID 23790398 DOI: 10.1016/J.Mib.2013.05.003  0.449
2013 Dokladny K, Zuhl MN, Mandell M, Bhattacharya D, Schneider S, Deretic V, Moseley PL. Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. The Journal of Biological Chemistry. 288: 14959-72. PMID 23576438 DOI: 10.1074/Jbc.M113.462408  0.302
2012 Castillo EF, Dekonenko A, Arko-Mensah J, Mandell MA, Dupont N, Jiang S, Delgado-Vargas M, Timmins GS, Bhattacharya D, Yang H, Hutt J, Lyons CR, Dobos KM, Deretic V. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation. Proceedings of the National Academy of Sciences of the United States of America. 109: E3168-76. PMID 23093667 DOI: 10.1073/Pnas.1210500109  0.369
2012 Pilli M, Arko-Mensah J, Ponpuak M, Roberts E, Master S, Mandell MA, Dupont N, Ornatowski W, Jiang S, Bradfute SB, Bruun JA, Hansen TE, Johansen T, Deretic V. TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation. Immunity. 37: 223-34. PMID 22921120 DOI: 10.1016/J.Immuni.2012.04.015  0.434
2009 Vickers TJ, Murta SM, Mandell MA, Beverley SM. The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major. Molecular and Biochemical Parasitology. 166: 142-52. PMID 19450731 DOI: 10.1016/J.Molbiopara.2009.03.009  0.49
2008 Ng LG, Hsu A, Mandell MA, Roediger B, Hoeller C, Mrass P, Iparraguirre A, Cavanagh LL, Triccas JA, Beverley SM, Scott P, Weninger W. Migratory dermal dendritic cells act as rapid sensors of protozoan parasites. Plos Pathogens. 4: e1000222. PMID 19043558 DOI: 10.1371/Journal.Ppat.1000222  0.554
2000 Kelleher JF, Mandell MA, Moulder G, Hill KL, L'Hernault SW, Barstead R, Titus MA. Myosin VI is required for asymmetric segregation of cellular components during C. elegans spermatogenesis. Current Biology : Cb. 10: 1489-96. PMID 11114515 DOI: 10.1016/S0960-9822(00)00828-9  0.303
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