Stefan Engelhardt - Publications

Pharmacology Technical University of Munich (TUM), München, Bayern, Germany 

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Year Citation  Score
2021 Ahles A, Engelhardt S. Glycosylation-dependent cleavage of the human β-adrenoceptor. Journal of Molecular and Cellular Cardiology. 154: 154-155. PMID 33711343 DOI: 10.1016/j.yjmcc.2021.03.002  0.56
2017 Ziegler KA, Ahles A, Wille T, Kerler J, Ramanujam D, Engelhardt S. Local sympathetic denervation attenuates myocardial inflammation and improves cardiac function after myocardial infarction in mice. Cardiovascular Research. PMID 29186414 DOI: 10.1093/Cvr/Cvx227  0.56
2017 Wang J, Hanada K, Staus DP, Makara MA, Dahal GR, Chen Q, Ahles A, Engelhardt S, Rockman HA. Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling. Nature Communications. 8: 1706. PMID 29167435 DOI: 10.1038/S41467-017-01855-Z  0.56
2017 Hinz L, Ahles A, Ruprecht B, Küster B, Engelhardt S. Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment. Plos One. 12: e0176450. PMID 28472170 DOI: 10.1371/Journal.Pone.0176450  0.56
2016 Brill MS, Kleele T, Ruschkies L, Wang M, Marahori NA, Reuter MS, Hausrat TJ, Weigand E, Fisher M, Ahles A, Engelhardt S, Bishop DL, Kneussel M, Misgeld T. Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination. Neuron. PMID 27773584 DOI: 10.1016/J.Neuron.2016.09.049  0.56
2016 Regn M, Laggerbauer B, Jentzsch C, Ramanujam D, Ahles A, Sichler S, Calzada-Wack J, Koenen R, Braun A, Nieswandt B, Engelhardt S. Peptidase inhibitor 16 is a membrane-tethered regulator of chemerin processing in the myocardium. Journal of Molecular and Cellular Cardiology. PMID 27539859 DOI: 10.1016/J.Yjmcc.2016.08.010  0.56
2016 Meyer K, Hodwin B, Ramanujam D, Engelhardt S, Sarikas A. Essential Role for Premature Senescence of Myofibroblasts in Myocardial Fibrosis. Journal of the American College of Cardiology. 67: 2018-28. PMID 27126529 DOI: 10.1016/J.Jacc.2016.02.047  0.72
2015 Engelhardt S, Sassi Y. MicroRNA Augmentation of Bone Marrow-Derived Cell Therapy. Journal of the American College of Cardiology. 66: 2227-9. PMID 26564601 DOI: 10.1016/J.Jacc.2015.09.053  0.72
2015 Keller K, Maaß M, Dizayee S, Leiss V, Annala S, Köth J, Seemann W, Müller-Ehmsen J, Mohr K, Nürnberg B, Engelhardt S, Herzig S, Birnbaumer L, Matthes J. Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice. Cardiovascular Research. PMID 26464333 DOI: 10.1093/Cvr/Cvv235  0.72
2015 Gentner B, Pochert N, Rouhi A, Boccalatte F, Plati T, Berg T, Sun SM, Mah SM, Mirkovic-Hösle M, Ruschmann J, Muranyi A, Leierseder S, Argiropoulos B, Starczynowski DT, Karsan A, ... ... Engelhardt S, et al. MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia. Experimental Hematology. 43: 858-868.e7. PMID 26163797 DOI: 10.1016/J.Exphem.2015.05.018  0.72
2015 Truong DJ, Kühner K, Kühn R, Werfel S, Engelhardt S, Wurst W, Ortiz O. Development of an intein-mediated split-Cas9 system for gene therapy. Nucleic Acids Research. PMID 26082496 DOI: 10.1093/Nar/Gkv601  0.72
2015 Ramanujam D, Engelhardt S. Intercellular miRNA Traffic. Circulation Research. 116: 1726-8. PMID 25999416 DOI: 10.1161/Circresaha.115.306519  0.72
2015 Gutmann J, Kühbeck F, Berberat PO, Fischer MR, Engelhardt S, Sarikas A. Use of learning media by undergraduate medical students in pharmacology: a prospective cohort study. Plos One. 10: e0122624. PMID 25849565 DOI: 10.1371/Journal.Pone.0122624  0.72
2015 Ahles A, Rodewald F, Rochais F, Bünemann M, Engelhardt S. Interhelical interaction and receptor phosphorylation regulate the activation kinetics of different human β1-adrenoceptor variants. The Journal of Biological Chemistry. 290: 1760-9. PMID 25451930 DOI: 10.1074/Jbc.M114.607333  0.72
2015 Feechan A, Turnbull D, Stevens LJ, Engelhardt S, Birch PRJ, Hein I, Gilroy EM. The hypersensitive response in PAMP- and effector-triggered immune responses Plant Programmed Cell Death. 327-368. DOI: 10.1007/978-3-319-21033-9_10  0.72
2014 Sassi Y, Ahles A, Truong DJ, Baqi Y, Lee SY, Husse B, Hulot JS, Foinquinos A, Thum T, Müller CE, Dendorfer A, Laggerbauer B, Engelhardt S. Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation. The Journal of Clinical Investigation. 124: 5385-97. PMID 25401477 DOI: 10.1172/Jci74349  0.72
2014 Chapman S, Stevens LJ, Boevink PC, Engelhardt S, Alexander CJ, Harrower B, Champouret N, McGeachy K, Van Weymers PS, Chen X, Birch PR, Hein I. Detection of the virulent form of AVR3a from Phytophthora infestans following artificial evolution of potato resistance gene R3a. Plos One. 9: e110158. PMID 25340613 DOI: 10.1371/Journal.Pone.0110158  0.72
2014 Kräenbring J, Monzon Penza T, Gutmann J, Muehlich S, Zolk O, Wojnowski L, Maas R, Engelhardt S, Sarikas A. Accuracy and completeness of drug information in Wikipedia: a comparison with standard textbooks of pharmacology. Plos One. 9: e106930. PMID 25250889 DOI: 10.1371/Journal.Pone.0106930  0.72
2014 Werfel S, Jungmann A, Lehmann L, Ksienzyk J, Bekeredjian R, Kaya Z, Leuchs B, Nordheim A, Backs J, Engelhardt S, Katus HA, Müller OJ. Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase. Cardiovascular Research. 104: 15-23. PMID 25082846 DOI: 10.1093/Cvr/Cvu174  0.72
2014 Ahles A, Engelhardt S. Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease. Pharmacological Reviews. 66: 598-637. PMID 24928328 DOI: 10.1124/Pr.113.008219  0.72
2014 Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, Ponimaskin E, Schmiedl A, Yin X, Mayr M, Halder R, ... ... Engelhardt S, et al. Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. The Journal of Clinical Investigation. 124: 2136-46. PMID 24743145 DOI: 10.1172/Jci70577  0.72
2014 Kühbeck F, Engelhardt S, Sarikas A. novel web-based audience response system for higher education. A pilot study to evaluate user acceptance. Gms Zeitschrift FüR Medizinische Ausbildung. 31: Doc5. PMID 24575156 DOI: 10.3205/zma000897  0.72
2014 Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan ZQ, Engelhardt S, Sarikas A. Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen. Proceedings of the National Academy of Sciences of the United States of America. 111: 3371-6. PMID 24550499 DOI: 10.1073/Pnas.1401556111  0.72
2014 Scheufele F, Wolf B, Kruse M, Hartmann T, Lempart J, Muehlich S, Pfeiffer AF, Field LJ, Charron MJ, Pan ZQ, Engelhardt S, Sarikas A. Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling. Cellular Signalling. 26: 233-9. PMID 24219910 DOI: 10.1016/J.Cellsig.2013.11.005  0.72
2013 Engelhardt S, Leierseder S. Coinciding functions for miR-145 in vascular smooth muscle and cardiac fibroblasts. Journal of Molecular and Cellular Cardiology. 65: 105-7. PMID 24140723 DOI: 10.1016/J.Yjmcc.2013.10.002  0.72
2013 Gurha P, Wang T, Larimore AH, Sassi Y, Abreu-Goodger C, Ramirez MO, Reddy AK, Engelhardt S, Taffet GE, Wehrens XH, Entman ML, Rodriguez A. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. Plos One. 8: e75882. PMID 24086656 DOI: 10.1371/Journal.Pone.0075882  0.72
2013 Leierseder S, Petzold T, Zhang L, Loyer X, Massberg S, Engelhardt S. MiR-223 is dispensable for platelet production and function in mice. Thrombosis and Haemostasis. 110: 1207-14. PMID 24067995 DOI: 10.1160/Th13-07-0623  0.72
2013 Milde M, Rinne A, Wunder F, Engelhardt S, Bünemann M. Dynamics of Gαi1 interaction with type 5 adenylate cyclase reveal the molecular basis for high sensitivity of Gi-mediated inhibition of cAMP production. The Biochemical Journal. 454: 515-23. PMID 23841650 DOI: 10.1042/Bj20130554  0.72
2013 Rinck A, Preusse M, Laggerbauer B, Lickert H, Engelhardt S, Theis FJ. The human transcriptome is enriched for miRNA-binding sites located in cooperativity-permitting distance. Rna Biology. 10: 1125-35. PMID 23696004 DOI: 10.4161/Rna.24955  0.72
2013 Ganesan J, Ramanujam D, Sassi Y, Ahles A, Jentzsch C, Werfel S, Leierseder S, Loyer X, Giacca M, Zentilin L, Thum T, Laggerbauer B, Engelhardt S. MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. Circulation. 127: 2097-106. PMID 23625957 DOI: 10.1161/Circulationaha.112.000882  0.72
2013 Sucha M, Engelhardt S, Sarikas A. Internet discussion forums as part of a student-centred teaching concept of pharmacology. Gms Zeitschrift FüR Medizinische Ausbildung. 30: Doc2. PMID 23467549 DOI: 10.3205/zma000845  0.72
2013 Zollner B, Sucha M, Berg C, Muß N, Amann P, Amann-Neher B, Oestreicher D, Engelhardt S, Sarikas A. - a student-centered e-learning project of clinical pharmacology. Medical Teacher. 35: 251-3. PMID 23339530 DOI: 10.3109/0142159X.2013.759642  0.72
2012 Engelhardt S, Boevink PC, Armstrong MR, Ramos MB, Hein I, Birch PR. Relocalization of late blight resistance protein R3a to endosomal compartments is associated with effector recognition and required for the immune response. The Plant Cell. 24: 5142-58. PMID 23243124 DOI: 10.1105/Tpc.112.104992  0.72
2012 Ucar A, Gupta SK, Fiedler J, Erikci E, Kardasinski M, Batkai S, Dangwal S, Kumarswamy R, Bang C, Holzmann A, Remke J, Caprio M, Jentzsch C, Engelhardt S, Geisendorf S, et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nature Communications. 3: 1078. PMID 23011132 DOI: 10.1038/Ncomms2090  0.72
2012 Engelhardt S. Small RNA biomarkers come of age. Journal of the American College of Cardiology. 60: 300-3. PMID 22813606 DOI: 10.1016/J.Jacc.2012.04.018  0.72
2012 Ziegler M, Elvers M, Baumer Y, Leder C, Ochmann C, Schönberger T, Jürgens T, Geisler T, Schlosshauer B, Lunov O, Engelhardt S, Simmet T, Gawaz M. The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice. Circulation. 125: 685-96. PMID 22223428 DOI: 10.1161/Circulationaha.111.070508  0.72
2012 Sassi Y, Abi-Gerges A, Fauconnier J, Mougenot N, Reiken S, Haghighi K, Kranias EG, Marks AR, Lacampagne A, Engelhardt S, Hatem SN, Lompre AM, Hulot JS. Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1009-17. PMID 22090316 DOI: 10.1096/Fj.11-194027  0.72
2012 Jentzsch C, Leierseder S, Loyer X, Flohrschütz I, Sassi Y, Hartmann D, Thum T, Laggerbauer B, Engelhardt S. A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. Journal of Molecular and Cellular Cardiology. 52: 13-20. PMID 21801730 DOI: 10.1016/J.Yjmcc.2011.07.010  0.72
2011 Ahles A, Rochais F, Frambach T, Bünemann M, Engelhardt S. A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor. Science Signaling. 4: ra53. PMID 21868359 DOI: 10.1126/Scisignal.2001681  0.72
2011 Hulot JS, Fauconnier J, Ramanujam D, Chaanine A, Aubart F, Sassi Y, Merkle S, Cazorla O, Ouillé A, Dupuis M, Hadri L, Jeong D, Mühlstedt S, Schmitt J, Braun A, ... ... Engelhardt S, et al. Critical role for stromal interaction molecule 1 in cardiac hypertrophy. Circulation. 124: 796-805. PMID 21810664 DOI: 10.1161/Circulationaha.111.031229  0.72
2011 Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, ... ... Engelhardt S, et al. MicroRNA-24 regulates vascularity after myocardial infarction. Circulation. 124: 720-30. PMID 21788589 DOI: 10.1161/Circulationaha.111.039008  0.72
2011 Seizer P, Ochmann C, Schönberger T, Zach S, Rose M, Borst O, Klingel K, Kandolf R, MacDonald HR, Nowak RA, Engelhardt S, Lang F, Gawaz M, May AE. Disrupting the EMMPRIN (CD147)-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1377-86. PMID 21441138 DOI: 10.1161/Atvbaha.111.225771  0.72
2011 Thum T, Chau N, Bhat B, Gupta SK, Linsley PS, Bauersachs J, Engelhardt S. Comparison of different miR-21 inhibitor chemistries in a cardiac disease model. The Journal of Clinical Investigation. 121: 461-2; author reply . PMID 21285516 DOI: 10.1172/Jci45938  0.72
2011 Haapalainen M, Engelhardt S, Küfner I, Li CM, Nürnberger T, Lee J, Romantschuk M, Taira S. Functional mapping of harpin HrpZ of Pseudomonas syringae reveals the sites responsible for protein oligomerization, lipid interactions and plant defence induction. Molecular Plant Pathology. 12: 151-66. PMID 21199565 DOI: 10.1111/j.1364-3703.2010.00655.x  0.72
2010 Bos JI, Armstrong MR, Gilroy EM, Boevink PC, Hein I, Taylor RM, Zhendong T, Engelhardt S, Vetukuri RR, Harrower B, Dixelius C, Bryan G, Sadanandom A, Whisson SC, Kamoun S, et al. Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1. Proceedings of the National Academy of Sciences of the United States of America. 107: 9909-14. PMID 20457921 DOI: 10.1073/Pnas.0914408107  0.72
2009 Ahles A, Engelhardt S. Polymorphisms determine beta-adrenoceptor conformation: implications for cardiovascular disease and therapy. Trends in Pharmacological Sciences. 30: 188-93. PMID 19272658 DOI: 10.1016/J.Tips.2009.02.001  0.72
2009 Dorsch S, Klotz KN, Engelhardt S, Lohse MJ, Bünemann M. Analysis of receptor oligomerization by FRAP microscopy. Nature Methods. 6: 225-30. PMID 19234451 DOI: 10.1038/Nmeth.1304  0.72
2009 Vilardaga JP, Bünemann M, Feinstein TN, Lambert N, Nikolaev VO, Engelhardt S, Lohse MJ, Hoffmann C. GPCR and G proteins: drug efficacy and activation in live cells. Molecular Endocrinology (Baltimore, Md.). 23: 590-9. PMID 19196832 DOI: 10.1210/Me.2008-0204  0.72
2009 Lewin G, Matus M, Basu A, Frebel K, Rohsbach SP, Safronenko A, Seidl MD, Stümpel F, Buchwalow I, König S, Engelhardt S, Lohse MJ, Schmitz W, Müller FU. Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction. Circulation. 119: 79-88. PMID 19103994 DOI: 10.1161/Circulationaha.108.786533  0.72
2009 Cook AR, Bardswell SC, Pretheshan S, Dighe K, Kanaganayagam GS, Jabr RI, Merkle S, Marber MS, Engelhardt S, Avkiran M. Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress? Journal of Molecular and Cellular Cardiology. 46: 225-33. PMID 19027022 DOI: 10.1016/J.Yjmcc.2008.10.013  0.72
2009 Engelhardt S, Lee J, Gäbler Y, Kemmerling B, Haapalainen ML, Li CM, Wei Z, Keller H, Joosten M, Taira S, Nürnberger T. Separable roles of the Pseudomonas syringae pv. phaseolicola accessory protein HrpZ1 in ion-conducting pore formation and activation of plant immunity. The Plant Journal : For Cell and Molecular Biology. 57: 706-17. PMID 18980650 DOI: 10.1111/j.1365-313X.2008.03723.x  0.72
2008 Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, ... ... Engelhardt S, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature. 456: 980-4. PMID 19043405 DOI: 10.1038/Nature07511  0.72
2007 Rohrbach S, Engelhardt S, Lohse MJ, Werdan K, Holtz J, Muller-Werdan U. Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6. Molecular Medicine (Cambridge, Mass.). 13: 605-14. PMID 17948064 DOI: 10.2119/2007-00071.Rohrbach  0.72
2007 Frost RJ, Engelhardt S. A secretion trap screen in yeast identifies protease inhibitor 16 as a novel antihypertrophic protein secreted from the heart. Circulation. 116: 1768-75. PMID 17909105 DOI: 10.1161/Circulationaha.107.696468  0.72
2007 Engelhardt S. Alternative signaling: cardiomyocyte beta1-adrenergic receptors signal through EGFRs. The Journal of Clinical Investigation. 117: 2396-8. PMID 17786237 DOI: 10.1172/Jci33135  0.72
2007 Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J. MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation. 116: 258-67. PMID 17606841 DOI: 10.1016/S1567-4215(07)60006-X  0.72
2007 Engelhardt S, Rochais F. G proteins: more than transducers of receptor-generated signals? Circulation Research. 100: 1109-11. PMID 17463326 DOI: 10.1161/01.Res.0000266971.15127.E8  0.72
2007 Peter PS, Brady JE, Yan L, Chen W, Engelhardt S, Wang Y, Sadoshima J, Vatner SF, Vatner DE. Inhibition of p38 alpha MAPK rescues cardiomyopathy induced by overexpressed beta 2-adrenergic receptor, but not beta 1-adrenergic receptor. The Journal of Clinical Investigation. 117: 1335-43. PMID 17446930 DOI: 10.1172/Jci29576  0.72
2007 Merkle S, Frantz S, Schön MP, Bauersachs J, Buitrago M, Frost RJ, Schmitteckert EM, Lohse MJ, Engelhardt S. A role for caspase-1 in heart failure. Circulation Research. 100: 645-53. PMID 17303764 DOI: 10.1161/01.Res.0000260203.55077.61  0.72
2007 Rochais F, Vilardaga JP, Nikolaev VO, Bünemann M, Lohse MJ, Engelhardt S. Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. The Journal of Clinical Investigation. 117: 229-35. PMID 17200720 DOI: 10.1172/Jci30012  0.72
2007 Seeland U, Selejan S, Engelhardt S, Müller P, Lohse MJ, Böhm M. Interstitial remodeling in beta1-adrenergic receptor transgenic mice. Basic Research in Cardiology. 102: 183-93. PMID 17122889 DOI: 10.1007/S00395-006-0635-Y  0.72
2006 Qutob D, Kemmerling B, Brunner F, Küfner I, Engelhardt S, Gust AA, Luberacki B, Seitz HU, Stahl D, Rauhut T, Glawischnig E, Schween G, Lacombe B, Watanabe N, Lam E, et al. Phytotoxicity and innate immune responses induced by Nep1-like proteins. The Plant Cell. 18: 3721-44. PMID 17194768 DOI: 10.1105/tpc.106.044180  0.72
2006 Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt S. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circulation Research. 99: 1084-91. PMID 17038640 DOI: 10.1161/01.Res.0000250046.69918.D5  0.72
2006 Hein P, Rochais F, Hoffmann C, Dorsch S, Nikolaev VO, Engelhardt S, Berlot CH, Lohse MJ, Bünemann M. Gs activation is time-limiting in initiating receptor-mediated signaling. The Journal of Biological Chemistry. 281: 33345-51. PMID 16963443 DOI: 10.1074/Jbc.M606713200  0.72
2006 Hallhuber M, Burkard N, Wu R, Buch MH, Engelhardt S, Hein L, Neyses L, Schuh K, Ritter O. Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy. Circulation Research. 99: 626-35. PMID 16931796 DOI: 10.1161/01.Res.0000243208.59795.D8  0.72
2006 Engelhardt S, Merkle S. Physiological and pathological myocardial growth? | Physiologisches und pathologisches myokardwachstum? Biospektrum. 12: 165-167.  0.72
2005 Engelhardt S. Beta-adrenergic receptors in heart failure. Heart Failure Clinics. 1: 183-91. PMID 17386845 DOI: 10.1016/J.Hfc.2005.04.005  0.72
2005 Racapé J, Belbahri L, Engelhardt S, Lacombe B, Lee J, Lochman J, Marais A, Nicole M, Nürnberger T, Parlange F, Puverel S, Keller H. Ca2+-dependent lipid binding and membrane integration of PopA, a harpin-like elicitor of the hypersensitive response in tobacco. Molecular Microbiology. 58: 1406-20. PMID 16313625 DOI: 10.1111/j.1365-2958.2004.04910.x  0.72
2005 Buitrago M, Lorenz K, Maass AH, Oberdorf-Maass S, Keller U, Schmitteckert EM, Ivashchenko Y, Lohse MJ, Engelhardt S. The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy. Nature Medicine. 11: 837-44. PMID 16025126 DOI: 10.1038/Nm1272  0.72
2005 Frambach T, Müller T, Freund S, Engelhardt S, Sütterlin M, Lohse MJ, Dietl J. Self-limitation of intravenous tocolysis with beta2-adrenergic agonists is mediated through receptor G protein uncoupling. The Journal of Clinical Endocrinology and Metabolism. 90: 2882-7. PMID 15728216 DOI: 10.1210/Jc.2004-1732  0.72
2005 Nikolaev VO, Gambaryan S, Engelhardt S, Walter U, Lohse MJ. Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. The Journal of Biological Chemistry. 280: 1716-9. PMID 15557342 DOI: 10.1074/Jbc.C400505200  0.72
2004 Otto C, Hein L, Brede M, Jahns R, Engelhardt S, Gröne HJ, Schütz G. Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice. Circulation. 110: 3245-51. PMID 15520307 DOI: 10.1161/01.Cir.0000147235.53360.59  0.72
2004 Witte K, Engelhardt S, Janssen BJ, Lohse M, Lemmer B. Circadian and short-term regulation of blood pressure and heart rate in transgenic mice with cardiac overexpression of the beta1-adrenoceptor. Chronobiology International. 21: 205-16. PMID 15332342 DOI: 10.1081/Cbi-120037801  0.72
2004 Zerkowski HR, Grussenmeyer T, Matt P, Grapow M, Engelhardt S, Lefkovits I. Proteomics strategies in cardiovascular research. Journal of Proteome Research. 3: 200-8. PMID 15113095 DOI: 10.1021/pr034079t  0.72
2004 Foerster K, Kaeferstein T, Groner F, Engelhardt S, Matthes J, Koch WJ, Lohse MJ, Herzig S. Calcium channel function and regulation in beta 1- and beta 2-adrenoceptor transgenic mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 369: 490-5. PMID 15083268 DOI: 10.1007/S00210-004-0928-3  0.72
2004 Engelhardt S, Hein L, Dyachenkow V, Kranias EG, Isenberg G, Lohse MJ. Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. Circulation. 109: 1154-60. PMID 14967726 DOI: 10.1161/01.Cir.0000117254.68497.39  0.72
2003 Gaussin V, Tomlinson JE, Depre C, Engelhardt S, Antos CL, Takagi G, Hein L, Topper JN, Liggett SB, Olson EN, Lohse MJ, Vatner SF, Vatner DE. Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy. Circulation. 108: 2926-33. PMID 14623810 DOI: 10.1161/01.Cir.0000101922.18151.7B  0.72
2003 Lohse MJ, Engelhardt S, Eschenhagen T. What is the role of beta-adrenergic signaling in heart failure? Circulation Research. 93: 896-906. PMID 14615493 DOI: 10.1161/01.Res.0000102042.83024.Ca  0.72
2003 Eigenthaler M, Engelhardt S, Schinke B, Kobsar A, Schmitteckert E, Gambaryan S, Engelhardt CM, Krenn V, Eliava M, Jarchau T, Lohse MJ, Walter U, Hein L. Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2471-81. PMID 12933343 DOI: 10.1152/Ajpheart.00362.2003  0.72
2003 Maack C, Böhm M, Vlaskin L, Dabew E, Lorenz K, Schäfers HJ, Lohse MJ, Engelhardt S. Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor. Circulation. 108: 348-53. PMID 12847069 DOI: 10.1161/01.Cir.0000080325.94345.8B  0.72
2003 Spindler M, Engelhardt S, Niebler R, Wagner H, Hein L, Lohse MJ, Neubauer S. Alterations in the myocardial creatine kinase system precede the development of contractile dysfunction in beta(1)-adrenergic receptor transgenic mice. Journal of Molecular and Cellular Cardiology. 35: 389-97. PMID 12689818 DOI: 10.1016/S0022-2828(03)00015-4  0.72
2002 Fellbrich G, Romanski A, Varet A, Blume B, Brunner F, Engelhardt S, Felix G, Kemmerling B, Krzymowska M, Nürnberger T. NPP1, a Phytophthora-associated trigger of plant defense in parsley and Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 32: 375-90. PMID 12410815 DOI: 10.1046/j.1365-313X.2002.01454.x  0.72
2002 Engelhardt S, Hein L, Keller U, Klämbt K, Lohse MJ. Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice. Circulation Research. 90: 814-9. PMID 11964375 DOI: 10.1161/01.Res.0000014966.97486.C0  0.72
2001 Lohse MJ, Engelhardt S. Protein kinase a transgenes: the many faces of cAMP. Circulation Research. 89: 938-40. PMID 11717148 DOI: 10.1161/Res.89.11.938  0.72
2001 Brede M, Hadamek K, Meinel L, Wiesmann F, Peters J, Engelhardt S, Simm A, Haase A, Lohse MJ, Hein L. Vascular hypertrophy and increased P70S6 kinase in mice lacking the angiotensin II AT(2) receptor. Circulation. 104: 2602-7. PMID 11714657 DOI: 10.1161/Hc4601.099401  0.72
2001 Engelhardt S, Boknik P, Keller U, Neumann J, Lohse MJ, Hein L. Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2718-20. PMID 11606476 DOI: 10.1096/Fj.01-0107Fje  0.72
2001 Engelhardt S, Grimmer Y, Fan GH, Lohse MJ. Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice. Molecular Pharmacology. 60: 712-7. PMID 11562432  0.72
2001 Wiesmann F, Ruff J, Engelhardt S, Hein L, Dienesch C, Leupold A, Illinger R, Frydrychowicz A, Hiller KH, Rommel E, Haase A, Lohse MJ, Neubauer S. Dobutamine-stress magnetic resonance microimaging in mice : acute changes of cardiac geometry and function in normal and failing murine hearts. Circulation Research. 88: 563-9. PMID 11282889 DOI: 10.1161/01.Res.88.6.563  0.72
2001 Kaumann AJ, Engelhardt S, Hein L, Molenaar P, Lohse M. Abolition of (-)-CGP 12177-evoked cardiostimulation in double β1/β2-adrenoceptor knockout mice. Obligatory role of β1-adrenoceptors for putative β4-adrenoceptor pharmacology Naunyn-Schmiedeberg's Archives of Pharmacology. 363: 87-93. PMID 11191841 DOI: 10.1007/S002100000336  0.72
2000 Engelhardt S, Lohse MJ. Determination of adrenergic receptor mRNAs by quantitative reverse transcriptase-polymerase chain reactions. Methods in Molecular Biology (Clifton, N.J.). 126: 155-68. PMID 10685408 DOI: 10.1385/1-59259-684-3:155  0.72
1999 Engelhardt S, Hein L, Wiesmann F, Lohse MJ. Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 7059-64. PMID 10359838 DOI: 10.1073/Pnas.96.12.7059  0.72
1997 Engelhardt S, Zieger W, Kassubek J, Michel MC, Lohse MJ, Brodde OE. Tocolytic therapy with fenoterol induces selective down-regulation of beta-adrenergic receptors in human myometrium. The Journal of Clinical Endocrinology and Metabolism. 82: 1235-42. PMID 9100601 DOI: 10.1210/Jcem.82.4.3885  0.72
1996 Lohse MJ, Engelhardt S, Danner S, Böhm M. Mechanisms of beta-adrenergic receptor desensitization: from molecular biology to heart failure. Basic Research in Cardiology. 91: 29-34. PMID 8957541 DOI: 10.1007/Bf00795359  0.72
1996 Engelhardt S, Böhm M, Erdmann E, Lohse MJ. Analysis of beta-adrenergic receptor mRNA levels in human ventricular biopsy specimens by quantitative polymerase chain reactions: progressive reduction of beta 1-adrenergic receptor mRNA in heart failure. Journal of the American College of Cardiology. 27: 146-54. PMID 8522688 DOI: 10.1016/0735-1097(95)00425-4  0.72
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