Viacheslav O. Nikolaev - Publications

Affiliations: 
2003-2010 Experimental Cardiovascular Research University of Hamburg, Hamburg, Hamburg, Germany 

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Donzelli S, Goetz M, Schmidt K, Wolters M, Stathopoulou K, Diering S, Prysyazhna O, Polat V, Scotcher J, Dees C, Subramanian H, Butt E, Kamynina A, Schobesberger S, King SB, ... Nikolaev VO, et al. Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity. Scientific Reports. 7: 9938. PMID 28855531 DOI: 10.1038/s41598-017-09275-1  0.36
2017 Rukoyatkina N, Butt E, Subramanian H, Nikolaev VO, Mindukshev I, Walter U, Gambaryan S, Benz PM. Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis. Cell Death & Disease. 8: e2898. PMID 28661475 DOI: 10.1038/cddis.2017.290  0.56
2017 Berisha F, Nikolaev VO. Cyclic nucleotide imaging and cardiovascular disease. Pharmacology & Therapeutics. PMID 28216026 DOI: 10.1016/j.pharmthera.2017.02.038  0.36
2016 Chen W, Spitzl A, Mathes DS, Nikolaev VO, Werner F, Weirather J, Spiranec K, Röck K, Fischer JW, Kämmerer U, Stegner D, Baba HA, Hofmann U, Frantz S, Kuhn M. Endothelial Actions of ANP Enhance Myocardial Inflammatory Infiltration in the Early Phase After Acute Infarction. Circulation Research. PMID 27142162 DOI: 10.1161/CIRCRESAHA.115.307196  1
2015 Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, Philippaert K, Reinbothe T, Rorsman N, Salehi A, Sones WR, Vergari E, Weston C, Gorelik J, Katsura M, ... Nikolaev VO, et al. GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation. The Journal of Clinical Investigation. PMID 26571400 DOI: 10.1172/JCI81975  1
2015 Froese A, Nikolaev VO. Imaging alterations of cardiomyocyte cAMP microdomains in disease. Frontiers in Pharmacology. 6: 172. PMID 26379548 DOI: 10.3389/fphar.2015.00172  1
2015 Straubinger J, Schöttle V, Bork N, Subramanian H, Dünnes S, Russwurm M, Gawaz M, Friebe A, Nemer M, Nikolaev VO, Lukowski R. Sildenafil Does Not Prevent Heart Hypertrophy and Fibrosis Induced by Cardiomyocyte Angiotensin II Type 1 Receptor Signaling. The Journal of Pharmacology and Experimental Therapeutics. 354: 406-16. PMID 26157043 DOI: 10.1124/jpet.115.226092  1
2015 Fischer TH, Herting J, Mason FE, Hartmann N, Watanabe S, Nikolaev VO, Sprenger JU, Fan P, Yao L, Popov AF, Danner BC, Schöndube F, Belardinelli L, Hasenfuss G, Maier LS, et al. Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII. Cardiovascular Research. 107: 184-96. PMID 25990311 DOI: 10.1093/cvr/cvv153  1
2015 Reddy GR, Subramanian H, Birk A, Milde M, Nikolaev VO, Bünemann M. Adenylyl cyclases 5 and 6 underlie PIP3-dependent regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 3458-71. PMID 25931510 DOI: 10.1096/fj.14-268466  1
2015 Sprenger JU, Perera RK, Steinbrecher JH, Lehnart SE, Maier LS, Hasenfuss G, Nikolaev VO. In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease. Nature Communications. 6: 6965. PMID 25917898 DOI: 10.1038/ncomms7965  1
2015 Hübscher D, Nikolaev VO. Generation of transgenic mice expressing FRET biosensors. Methods in Molecular Biology (Clifton, N.J.). 1294: 117-29. PMID 25783881 DOI: 10.1007/978-1-4939-2537-7_9  1
2015 Shuhaibar LC, Egbert JR, Norris RP, Lampe PD, Nikolaev VO, Thunemann M, Wen L, Feil R, Jaffe LA. Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles. Proceedings of the National Academy of Sciences of the United States of America. 112: 5527-32. PMID 25775542 DOI: 10.1073/pnas.1423598112  1
2015 Boivin V, Beyersdorf N, Palm D, Nikolaev VO, Schlipp A, Müller J, Schmidt D, Kocoski V, Kerkau T, Hünig T, Ertl G, Lohse MJ, Jahns R. Novel receptor-derived cyclopeptides to treat heart failure caused by anti-β1-adrenoceptor antibodies in a human-analogous rat model. Plos One. 10: e0117589. PMID 25700031 DOI: 10.1371/journal.pone.0117589  1
2015 Perera RK, Sprenger JU, Steinbrecher JH, Hübscher D, Lehnart SE, Abesser M, Schuh K, El-Armouche A, Nikolaev VO. Microdomain switch of cGMP-regulated phosphodiesterases leads to ANP-induced augmentation of β-adrenoceptor-stimulated contractility in early cardiac hypertrophy. Circulation Research. 116: 1304-11. PMID 25688144 DOI: 10.1161/CIRCRESAHA.116.306082  1
2015 Lelle M, Hameed A, Ackermann LM, Kaloyanova S, Wagner M, Berisha F, Nikolaev VO, Peneva K. Functional non-nucleoside adenylyl cyclase inhibitors. Chemical Biology & Drug Design. 85: 633-7. PMID 25319071 DOI: 10.1111/cbdd.12452  1
2014 Nakagawa H, Oberwinkler H, Nikolaev VO, Gaßner B, Umbenhauer S, Wagner H, Saito Y, Baba HA, Frantz S, Kuhn M. Atrial natriuretic peptide locally counteracts the deleterious effects of cardiomyocyte mineralocorticoid receptor activation. Circulation. Heart Failure. 7: 814-21. PMID 25027872 DOI: 10.1161/CIRCHEARTFAILURE.113.000885  1
2014 Dybkova N, Wagner S, Backs J, Hund TJ, Mohler PJ, Sowa T, Nikolaev VO, Maier LS. Tubulin polymerization disrupts cardiac β-adrenergic regulation of late INa. Cardiovascular Research. 103: 168-77. PMID 24812278 DOI: 10.1093/cvr/cvu120  1
2014 Agarwal SR, Yang PC, Rice M, Singer CA, Nikolaev VO, Lohse MJ, Clancy CE, Harvey RD. Role of membrane microdomains in compartmentation of cAMP signaling. Plos One. 9: e95835. PMID 24752595 DOI: 10.1371/journal.pone.0095835  1
2014 Götz KR, Sprenger JU, Perera RK, Steinbrecher JH, Lehnart SE, Kuhn M, Gorelik J, Balligand JL, Nikolaev VO. Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes. Circulation Research. 114: 1235-45. PMID 24599804 DOI: 10.1161/CIRCRESAHA.114.302437  1
2014 Vettel C, Lämmle S, Ewens S, Cervirgen C, Emons J, Ongherth A, Dewenter M, Lindner D, Westermann D, Nikolaev VO, Lutz S, Zimmermann WH, El-Armouche A. PDE2-mediated cAMP hydrolysis accelerates cardiac fibroblast to myofibroblast conversion and is antagonized by exogenous activation of cGMP signaling pathways American Journal of Physiology - Heart and Circulatory Physiology. 306: H1246-H1252. PMID 24531807 DOI: 10.1152/ajpheart.00852.2013  1
2014 Wright PT, Nikolaev VO, O'Hara T, Diakonov I, Bhargava A, Tokar S, Schobesberger S, Shevchuk AI, Sikkel MB, Wilkinson R, Trayanova NA, Lyon AR, Harding SE, Gorelik J. Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling. Journal of Molecular and Cellular Cardiology. 67: 38-48. PMID 24345421 DOI: 10.1016/j.yjmcc.2013.12.003  1
2014 Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, et al. Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase. Circulation. 129: 451-62. PMID 24190960 DOI: 10.1161/CIRCULATIONAHA.113.004940  1
2014 Cazabat L, Ragazzon B, Varin A, Potier-Cartereau M, Vandier C, Vezzosi D, Risk-Rabin M, Guellich A, Schittl J, Lechêne P, Richter W, Nikolaev VO, Zhang J, Bertherat J, Vandecasteele G. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters. Human Molecular Genetics. 23: 1163-74. PMID 24122441 DOI: 10.1093/hmg/ddt510  1
2013 Couto A, Oda S, Nikolaev VO, Soltesz Z, de Bono M. In vivo genetic dissection of O2-evoked cGMP dynamics in a Caenorhabditis elegans gas sensor. Proceedings of the National Academy of Sciences of the United States of America. 110: E3301-10. PMID 23940325 DOI: 10.1073/pnas.1217428110  1
2013 Leavesley SJ, Britain AL, Cichon LK, Nikolaev VO, Rich TC. Assessing FRET using spectral techniques. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 83: 898-912. PMID 23929684 DOI: 10.1002/cyto.a.22340  1
2013 Lowther KM, Uliasz TF, Götz KR, Nikolaev VO, Mehlmann LM. Regulation of Constitutive GPR3 Signaling and Surface Localization by GRK2 and β-arrestin-2 Overexpression in HEK293 Cells. Plos One. 8: e65365. PMID 23826079 DOI: 10.1371/journal.pone.0065365  1
2013 Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, ... ... Nikolaev VO, et al. Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes. Journal of the American College of Cardiology. 62: 1596-606. PMID 23810893 DOI: 10.1016/j.jacc.2013.05.057  1
2013 Götz KR, Nikolaev VO. Advances and techniques to measure cGMP in intact cardiomyocytes. Methods in Molecular Biology (Clifton, N.J.). 1020: 121-9. PMID 23709029 DOI: 10.1007/978-1-62703-459-3_7  1
2013 Sprenger JU, Nikolaev VO. Biophysical techniques for detection of cAMP and cGMP in living cells. International Journal of Molecular Sciences. 14: 8025-46. PMID 23584022 DOI: 10.3390/ijms14048025  1
2013 Perera RK, Nikolaev VO. Compartmentation of cAMP signalling in cardiomyocytes in health and disease. Acta Physiologica (Oxford, England). 207: 650-62. PMID 23383621 DOI: 10.1111/apha.12077  1
2012 Ghigo A, Perino A, Mehel H, Zahradníková A, Morello F, Leroy J, Nikolaev VO, Damilano F, Cimino J, De Luca E, Richter W, Westenbroek R, Catterall WA, Zhang J, Yan C, et al. Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. Circulation. 126: 2073-83. PMID 23008439 DOI: 10.1161/CIRCULATIONAHA.112.114074  1
2012 Sprenger JU, Perera RK, Götz KR, Nikolaev VO. FRET microscopy for real-time monitoring of signaling events in live cells using unimolecular biosensors. Journal of Visualized Experiments : Jove. e4081. PMID 22929080 DOI: 10.3791/4081  1
2012 Paur H, Wright PT, Sikkel MB, Tranter MH, Mansfield C, O'Gara P, Stuckey DJ, Nikolaev VO, Diakonov I, Pannell L, Gong H, Sun H, Peters NS, Petrou M, Zheng Z, et al. High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy. Circulation. 126: 697-706. PMID 22732314 DOI: 10.1161/CIRCULATIONAHA.112.111591  1
2012 Gambaryan S, Butt E, Kobsar A, Geiger J, Rukoyatkina N, Parnova R, Nikolaev VO, Walter U. The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells. British Journal of Pharmacology. 167: 826-38. PMID 22612416 DOI: 10.1111/j.1476-5381.2012.02044.x  1
2012 Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J. Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circulation. Heart Failure. 5: 357-65. PMID 22456061 DOI: 10.1161/CIRCHEARTFAILURE.111.964692  1
2012 Froese A, Breher SS, Waldeyer C, Schindler RF, Nikolaev VO, Rinné S, Wischmeyer E, Schlueter J, Becher J, Simrick S, Vauti F, Kuhtz J, Meister P, Kreissl S, Torlopp A, et al. Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. The Journal of Clinical Investigation. 122: 1119-30. PMID 22354168 DOI: 10.1172/JCI59410  1
2012 Mindukshev I, Gambaryan S, Kehrer L, Schuetz C, Kobsar A, Rukoyatkina N, Nikolaev VO, Krivchenko A, Watson SP, Walter U, Geiger J. Low angle light scattering analysis: a novel quantitative method for functional characterization of human and murine platelet receptors. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 50: 1253-62. PMID 22149738 DOI: 10.1515/CCLM.2011.817  1
2012 Chen W, Gassner B, Börner S, Nikolaev VO, Schlegel N, Waschke J, Steinbronn N, Strasser R, Kuhn M. Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway. Cardiovascular Research. 93: 141-51. PMID 22025581 DOI: 10.1093/cvr/cvr279  1
2011 Klaiber M, Dankworth B, Kruse M, Hartmann M, Nikolaev VO, Yang RB, Völker K, Gassner B, Oberwinkler H, Feil R, Freichel M, Groschner K, Skryabin BV, Frantz S, Birnbaumer L, et al. A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide. Proceedings of the National Academy of Sciences of the United States of America. 108: 18500-5. PMID 22027011 DOI: 10.1073/pnas.1103300108  1
2011 Nikolaev VO. [cAMP, cGMP and their visualization in living cells using fluorescent microscopy]. Tsitologiia. 53: 623-32. PMID 21961281  1
2011 Miragoli M, Kadir SH, Sheppard MN, Salvarani N, Virta M, Wells S, Lab MJ, Nikolaev VO, Moshkov A, Hague WM, Rohr S, Williamson C, Gorelik J. A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Hepatology (Baltimore, Md.). 54: 1282-92. PMID 21809354 DOI: 10.1002/hep.24492  1
2011 Börner S, Schwede F, Schlipp A, Berisha F, Calebiro D, Lohse MJ, Nikolaev VO. FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells. Nature Protocols. 6: 427-38. PMID 21412271 DOI: 10.1038/nprot.2010.198  1
2011 Lowther KM, Nikolaev VO, Mehlmann LM. Endocytosis in the mouse oocyte and its contribution to cAMP signaling during meiotic arrest. Reproduction (Cambridge, England). 141: 737-47. PMID 21411693 DOI: 10.1530/REP-10-0461  1
2011 Frölich N, Dees C, Paetz C, Ren X, Lohse MJ, Nikolaev VO, Zenk MH. Distinct pharmacological properties of morphine metabolites at G i-protein and β-arrestin signaling pathways activated by the human μ-opioid receptor Biochemical Pharmacology. 81: 1248-1254. PMID 21396918 DOI: 10.1016/j.bcp.2011.03.001  1
2011 Miragoli M, Moshkov A, Novak P, Shevchuk A, Nikolaev VO, El-Hamamsy I, Potter CM, Wright P, Kadir SH, Lyon AR, Mitchell JA, Chester AH, Klenerman D, Lab MJ, Korchev YE, et al. Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells. Journal of the Royal Society, Interface / the Royal Society. 8: 913-25. PMID 21325316 DOI: 10.1098/rsif.2010.0597  1
2010 Norris RP, Freudzon M, Nikolaev VO, Jaffe LA. Epidermal growth factor receptor kinase activity is required for gap junction closure and for part of the decrease in ovarian follicle cGMP in response to LH. Reproduction (Cambridge, England). 140: 655-62. PMID 20826538 DOI: 10.1530/REP-10-0288  1
2010 Jacobs S, Calebiro D, Nikolaev VO, Lohse MJ, Schulz S. Real-time monitoring of somatostatin receptor-cAMP signaling in live pituitary. Endocrinology. 151: 4560-5. PMID 20610560 DOI: 10.1210/en.2010-0341  1
2010 Castro LR, Gervasi N, Guiot E, Cavellini L, Nikolaev VO, Paupardin-Tritsch D, Vincent P. Type 4 phosphodiesterase plays different integrating roles in different cellular domains in pyramidal cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6143-51. PMID 20427672 DOI: 10.1523/JNEUROSCI.5851-09.2010  1
2010 Calebiro D, Nikolaev VO, Lohse MJ. Imaging of persistent cAMP signaling by internalized G protein-coupled receptors. Journal of Molecular Endocrinology. 45: 1-8. PMID 20378719 DOI: 10.1677/JME-10-0014  1
2010 Calebiro D, Nikolaev VO, Persani L, Lohse MJ. Signaling by internalized G-protein-coupled receptors. Trends in Pharmacological Sciences. 31: 221-8. PMID 20303186 DOI: 10.1016/j.tips.2010.02.002  1
2010 Sheikh Abdul Kadir SH, Miragoli M, Abu-Hayyeh S, Moshkov AV, Xie Q, Keitel V, Nikolaev VO, Williamson C, Gorelik J. Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes. Plos One. 5: e9689. PMID 20300620 DOI: 10.1371/journal.pone.0009689  1
2010 Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J. Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science (New York, N.Y.). 327: 1653-7. PMID 20185685 DOI: 10.1126/science.1185988  1
2010 Maier-Peuschel M, Frölich N, Dees C, Hommers LG, Hoffmann C, Nikolaev VO, Lohse MJ. A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation. The Journal of Biological Chemistry. 285: 8793-800. PMID 20083608 DOI: 10.1074/jbc.M109.098517  1
2010 Wachten S, Masada N, Ayling LJ, Ciruela A, Nikolaev VO, Lohse MJ, Cooper DM. Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells. Journal of Cell Science. 123: 95-106. PMID 20016070 DOI: 10.1242/jcs.058594  1
2010 von Hayn K, Werthmann RC, Nikolaev VO, Hommers LG, Lohse MJ, Bünemann M. Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 298: C324-32. PMID 19889965 DOI: 10.1152/ajpcell.00197.2009  1
2009 Calebiro D, Nikolaev VO, Gagliani MC, de Filippis T, Dees C, Tacchetti C, Persani L, Lohse MJ. Persistent cAMP-signals triggered by internalized G-protein-coupled receptors. Plos Biology. 7: e1000172. PMID 19688034 DOI: 10.1371/journal.pbio.1000172  1
2009 Adachi E, Kazoe Y, Sato Y, Suzuki Y, Urano T, Ueyama T, Saito N, Nikolaev VO, Lohse MJ, Tominaga M, Mogami H. A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy. PflüGers Archiv : European Journal of Physiology. 459: 227-34. PMID 19680684 DOI: 10.1007/s00424-009-0705-8  1
2009 Werthmann RC, von Hayn K, Nikolaev VO, Lohse MJ, Bünemann M. Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6. The Journal of Physiology. 587: 4091-104. PMID 19546162 DOI: 10.1113/jphysiol.2009.172957  1
2009 Norris RP, Ratzan WJ, Freudzon M, Mehlmann LM, Krall J, Movsesian MA, Wang H, Ke H, Nikolaev VO, Jaffe LA. Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte. Development (Cambridge, England). 136: 1869-78. PMID 19429786 DOI: 10.1242/dev.035238  1
2009 Nakagawa Y, Nagasawa M, Yamada S, Hara A, Mogami H, Nikolaev VO, Lohse MJ, Shigemura N, Ninomiya Y, Kojima I. Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. Plos One. 4: e5106. PMID 19352508 DOI: 10.1371/journal.pone.0005106  1
2009 Mironov SL, Skorova E, Taschenberger G, Hartelt N, Nikolaev VO, Lohse MJ, Kügler S. Imaging cytoplasmic cAMP in mouse brainstem neurons. Bmc Neuroscience. 10: 29. PMID 19327133 DOI: 10.1186/1471-2202-10-29  1
2009 Vilardaga JP, Bünemann M, Feinstein TN, Lambert N, Nikolaev VO, Engelhardt S, Lohse MJ, Hoffmann C. GPCR and G proteins: drug efficacy and activation in live cells. Molecular Endocrinology (Baltimore, Md.). 23: 590-9. PMID 19196832 DOI: 10.1210/me.2008-0204  1
2009 Nikolaev VO, Lohse MJ. Novel techniques for real-time monitoring of cGMP in living cells. Handbook of Experimental Pharmacology. 229-43. PMID 19089332 DOI: 10.1007/978-3-540-68964-5_11  1
2008 Hartmann M, Skryabin BV, Müller T, Gazinski A, Schröter J, Gassner B, Nikolaev VO, Bünemann M, Kuhn M. Alternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signaling. The Journal of Biological Chemistry. 283: 28313-20. PMID 18713751 DOI: 10.1074/jbc.M805521200  1
2008 Sassi Y, Lipskaia L, Vandecasteele G, Nikolaev VO, Hatem SN, Cohen Aubart F, Russel FG, Mougenot N, Vrignaud C, Lechat P, Lompré AM, Hulot JS. Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation. The Journal of Clinical Investigation. 118: 2747-57. PMID 18636120 DOI: 10.1172/JCI35067  1
2008 Müller II, Klingel K, Nikolaev VO, Jahns R, Gawaz MP, Weig HJ. Immunoadsorption in a 40 year old man with dilated cardiomyopathy and underlying active myocarditis. Clinical Research in Cardiology : Official Journal of the German Cardiac Society. 97: 787-90. PMID 18633566 DOI: 10.1007/s00392-008-0689-y  1
2008 Iancu RV, Ramamurthy G, Warrier S, Nikolaev VO, Lohse MJ, Jones SW, Harvey RD. Cytoplasmic cAMP concentrations in intact cardiac myocytes. American Journal of Physiology. Cell Physiology. 295: C414-22. PMID 18550706 DOI: 10.1152/ajpcell.00038.2008  1
2008 Herget S, Lohse MJ, Nikolaev VO. Real-time monitoring of phosphodiesterase inhibition in intact cells. Cellular Signalling. 20: 1423-31. PMID 18467075 DOI: 10.1016/j.cellsig.2008.03.011  1
2008 Shafer OT, Kim DJ, Dunbar-Yaffe R, Nikolaev VO, Lohse MJ, Taghert PH. Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging. Neuron. 58: 223-37. PMID 18439407 DOI: 10.1016/j.neuron.2008.02.018  1
2008 Leroy J, Abi-Gerges A, Nikolaev VO, Richter W, Lechêne P, Mazet JL, Conti M, Fischmeister R, Vandecasteele G. Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases. Circulation Research. 102: 1091-100. PMID 18369156 DOI: 10.1161/CIRCRESAHA.107.167817  1
2008 Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bünemann M. Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends in Pharmacological Sciences. 29: 159-65. PMID 18262662 DOI: 10.1016/j.tips.2007.12.002  1
2008 Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Kinetics of G-protein-coupled receptor signals in intact cells. British Journal of Pharmacology. 153: S125-32. PMID 18193071 DOI: 10.1038/sj.bjp.0707656  1
2008 Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nature Chemical Biology. 4: 126-31. PMID 18193048 DOI: 10.1038/nchembio.64  1
2007 Lohse MJ, Bünemann M, Hoffmann C, Vilardaga JP, Nikolaev VO. Monitoring receptor signaling by intramolecular FRET. Current Opinion in Pharmacology. 7: 547-53. PMID 17919975 DOI: 10.1016/j.coph.2007.08.007  1
2007 Lohse MJ, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells. Advances in Protein Chemistry. 74: 167-88. PMID 17854658 DOI: 10.1016/S0065-3233(07)74005-6  1
2007 Nikolaev VO, Boivin V, Störk S, Angermann CE, Ertl G, Lohse MJ, Jahns R. A novel fluorescence method for the rapid detection of functional beta1-adrenergic receptor autoantibodies in heart failure. Journal of the American College of Cardiology. 50: 423-31. PMID 17662395 DOI: 10.1016/j.jacc.2007.03.051  1
2007 Nikolaev VO, Boettcher C, Dees C, Bünemann M, Lohse MJ, Zenk MH. Live cell monitoring of μ-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors Journal of Biological Chemistry. 282: 27126-27132. PMID 17616524 DOI: 10.1074/jbc.M703272200  1
2007 Warrier S, Ramamurthy G, Eckert RL, Nikolaev VO, Lohse MJ, Harvey RD. cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes. The Journal of Physiology. 580: 765-76. PMID 17289786 DOI: 10.1113/jphysiol.2006.124891  1
2007 Rochais F, Vilardaga JP, Nikolaev VO, Bünemann M, Lohse MJ, Engelhardt S. Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. The Journal of Clinical Investigation. 117: 229-35. PMID 17200720 DOI: 10.1172/JCI30012  1
2006 Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt S. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling. Circulation Research. 99: 1084-91. PMID 17038640 DOI: 10.1161/01.RES.0000250046.69918.d5  1
2006 Harbeck MC, Chepurny O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW. Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells. Science's Stke : Signal Transduction Knowledge Environment. 2006: pl6. PMID 16985238 DOI: 10.1126/stke.3532006pl6  1
2006 Hein P, Rochais F, Hoffmann C, Dorsch S, Nikolaev VO, Engelhardt S, Berlot CH, Lohse MJ, Bünemann M. Gs activation is time-limiting in initiating receptor-mediated signaling. The Journal of Biological Chemistry. 281: 33345-51. PMID 16963443 DOI: 10.1074/jbc.M606713200  1
2006 Nikolaev VO, Hoffmann C, Bünemann M, Lohse MJ, Vilardaga JP. Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer. The Journal of Biological Chemistry. 281: 24506-11. PMID 16787921 DOI: 10.1074/jbc.M603266200  1
2006 Nikolaev VO, Lohse MJ. Monitoring of cAMP synthesis and degradation in living cells. Physiology (Bethesda, Md.). 21: 86-92. PMID 16565474 DOI: 10.1152/physiol.00057.2005  1
2006 Nikolaev VO, Gambaryan S, Lohse MJ. Fluorescent sensors for rapid monitoring of intracellular cGMP. Nature Methods. 3: 23-5. PMID 16369548 DOI: 10.1038/nmeth816  1
2005 Castro M, Nikolaev VO, Palm D, Lohse MJ, Vilardaga JP. Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism. Proceedings of the National Academy of Sciences of the United States of America. 102: 16084-9. PMID 16236727 DOI: 10.1073/pnas.0503942102  1
2005 Landa LR, Harbeck M, Kaihara K, Chepurny O, Kitiphongspattana K, Graf O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW. Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line. The Journal of Biological Chemistry. 280: 31294-302. PMID 15987680 DOI: 10.1074/jbc.M505657200  1
2005 Nikolaev VO, Gambaryan S, Engelhardt S, Walter U, Lohse MJ. Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis. The Journal of Biological Chemistry. 280: 1716-9. PMID 15557342 DOI: 10.1074/jbc.C400505200  1
2005 Nikolaev VO, Lohse MJ. Visualization of cAMP in living cells | Visualisierung von cAMP in lebenden zellen Biospektrum. 11: 724-726.  1
2004 Nikolaev VO, Bünemann M, Hein L, Hannawacker A, Lohse MJ. Novel single chain cAMP sensors for receptor-induced signal propagation. The Journal of Biological Chemistry. 279: 37215-8. PMID 15231839 DOI: 10.1074/jbc.C400302200  1
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