| Year |
Citation |
Score |
| 2023 |
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, ... ... Vilardaga JP, et al. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144. PMID 38123151 DOI: 10.1111/bph.16177 |
0.383 |
|
| 2023 |
Portales-Castillo I, Dean T, Cheloha RW, Creemer BA, Vilardaga JP, Savransky S, Khatri A, Jüppner H, Gardella TJ. Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome. Communications Biology. 6: 599. PMID 37268817 DOI: 10.1038/s42003-023-04966-0 |
0.443 |
|
| 2022 |
Vilardaga JP, Clark LJ, White AD, Sutkeviciute I, Lee JY, Bahar I. Molecular Mechanisms of PTH/PTHrP class B GPCR Signaling and Pharmacological Implications. Endocrine Reviews. PMID 36503956 DOI: 10.1210/endrev/bnac032 |
0.566 |
|
| 2022 |
Peña KA, White AD, Savransky S, Castillo IP, Jean-Alphonse FG, Gardella TJ, Sutkeviciute I, Vilardaga JP. Biased GPCR signaling by the native parathyroid hormone-related protein 1-141 relative to its N-terminal fragment 1-36. The Journal of Biological Chemistry. 102332. PMID 35933010 DOI: 10.1016/j.jbc.2022.102332 |
0.541 |
|
| 2021 |
Sutkeviciute I, Lee JY, White AD, Maria CS, Peña KA, Savransky S, Doruker P, Li H, Lei S, Kaynak B, Tu C, Clark LJ, Sanker S, Gardella TJ, Chang W, ... ... Vilardaga JP, et al. Precise druggability of the PTH type 1 receptor. Nature Chemical Biology. PMID 34949836 DOI: 10.1038/s41589-021-00929-w |
0.453 |
|
| 2021 |
White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, ... ... Vilardaga JP, et al. Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation. Science Signaling. 14: eabc5944. PMID 34609896 DOI: 10.1126/scisignal.abc5944 |
0.374 |
|
| 2021 |
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, ... ... Vilardaga JP, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156. PMID 34529832 DOI: 10.1111/bph.15538 |
0.376 |
|
| 2021 |
Vilardaga JP, Sutkeviciute I, Peña KA. Shining light on location-biased cAMP signaling. The Journal of Biological Chemistry. 297: 101118. PMID 34437901 DOI: 10.1016/j.jbc.2021.101118 |
0.372 |
|
| 2020 |
Daley EJ, Khatri A, Dean T, Vilardaga JP, Zaidi SA, Katritch V, Gardella TJ. Ligand-Dependent Effects of Methionine-8 Oxidation in Parathyroid Hormone Peptide Analogs. Endocrinology. PMID 33242090 DOI: 10.1210/endocr/bqaa216 |
0.31 |
|
| 2020 |
Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, ... ... Vilardaga JP, et al. Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature Chemical Biology. PMID 32632293 DOI: 10.1038/S41589-020-0567-0 |
0.611 |
|
| 2020 |
Sutkeviciute I, Vilardaga JP. Structural insights into emergent signaling modes of G protein-coupled receptors. The Journal of Biological Chemistry. PMID 32571882 DOI: 10.1074/Jbc.Rev120.009348 |
0.58 |
|
| 2020 |
White AD, Jean-Alphonse FG, Fang F, Peña KA, Liu S, König GM, Inoue A, Aslanoglou D, Gellman SH, Kostenis E, Xiao K, Vilardaga JP. G-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR. Proceedings of the National Academy of Sciences of the United States of America. PMID 32184323 DOI: 10.1073/Pnas.1918158117 |
0.587 |
|
| 2019 |
Sutkeviciute I, Clark LJ, White AD, Gardella TJ, Vilardaga JP. PTH/PTHrP Receptor Signaling, Allostery, and Structures. Trends in Endocrinology and Metabolism: Tem. 30: 860-874. PMID 31699241 DOI: 10.1016/J.Tem.2019.07.011 |
0.536 |
|
| 2019 |
Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH. Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. Journal of the American Chemical Society. PMID 31496241 DOI: 10.1021/Jacs.9B04179 |
0.431 |
|
| 2019 |
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, ... ... Vilardaga JP, et al. Structure and dynamics of the active human parathyroid hormone receptor-1. Science (New York, N.Y.). 364: 148-153. PMID 30975883 DOI: 10.1126/science.aav7942 |
0.55 |
|
| 2019 |
White AD, Fang F, Jean-Alphonse FG, Clark LJ, An HJ, Liu H, Zhao Y, Reynolds SL, Lee S, Xiao K, Sutkeviciute I, Vilardaga JP. Ca allostery in PTH-receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718391 DOI: 10.1073/Pnas.1814670116 |
0.554 |
|
| 2019 |
Bisello A, Chorev M, Friedman PA, Gardella T, Hills R, Jueppner H, Martin TJ, Nissenson RA, Potts, Jr. JT, Silve C, Usdin TB, Vilardaga J. Parathyroid hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f53/2019.4 |
0.444 |
|
| 2019 |
Clark L, Bondarenko V, Tang P, Vilardaga J. SAT-040 Structural Mechanisms of Parathyroid Hormone (PTH) Binding to Receptor and Regulation of Endosomal Signaling Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-040 |
0.525 |
|
| 2019 |
Sutkeviciute I, Zhao L, Zhang Y, Xu HE, Vilardaga J. OR30-3 Structural Basis of Activation and Sustained Signaling by the PTH Receptor Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or30-3 |
0.568 |
|
| 2019 |
White A, Sutkeviciute I, Jean-Alphonse F, Xiao K, Vilardaga J. MON-538 Ca2+Allostery in PTH-Receptor Signaling Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-538 |
0.472 |
|
| 2018 |
Naim N, White AD, Reece JM, Wankhede M, Zhang X, Vilardaga JP, Altschuler DL. Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis. The Journal of Biological Chemistry. PMID 30559293 DOI: 10.1074/Jbc.Ac118.004905 |
0.386 |
|
| 2018 |
Suofu Y, Carlisle DL, Vilardaga JP, Friedlander RM. Reply to Ahluwalia et al.: Contributions of melatonin receptors are tissue-dependent. Proceedings of the National Academy of Sciences of the United States of America. PMID 29440383 DOI: 10.1073/Pnas.1800449115 |
0.441 |
|
| 2017 |
Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, Baranov SV, Leronni D, Mihalik AC, He Y, Cecon E, Wehbi VL, Kim J, Heath BE, Baranova OV, ... ... Vilardaga JP, et al. Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874589 DOI: 10.1073/Pnas.1705768114 |
0.533 |
|
| 2017 |
Gbahou F, Cecon E, Viault G, Gerbier R, Jean-Alphonse F, Karamitri A, Guillaumet G, Delagrange P, Friedlander RM, Vilardaga JP, Suzenet F, Jockers R. Design and validation of the first cell-impermeant melatonin receptor agonist. British Journal of Pharmacology. PMID 28493341 DOI: 10.1111/Bph.13856 |
0.687 |
|
| 2016 |
Jean-Alphonse FG, Wehbi VL, Chen J, Noda M, Taboas JM, Xiao K, Vilardaga JP. β2-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ. Nature Chemical Biology. PMID 28024151 DOI: 10.1038/Nchembio.2267 |
0.674 |
|
| 2016 |
McGarvey JC, Xiao K, Bowman SL, Mamonova T, Zhang Q, Bisello A, Sneddon WB, Ardura JA, Jean-Alphonse F, Vilardaga JP, Puthenveedu MA, Friedman PA. Actin-Sorting Nexin 27-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling. The Journal of Biological Chemistry. PMID 27008860 DOI: 10.1074/Jbc.M115.697045 |
0.489 |
|
| 2016 |
Gidon A, Feinstein TN, Xiao K, Vilardaga JP. Studying the regulation of endosomal cAMP production in GPCR signaling. Methods in Cell Biology. 132: 109-26. PMID 26928541 DOI: 10.1016/Bs.Mcb.2015.10.007 |
0.601 |
|
| 2016 |
Tahimic CG, Long RK, Kubota T, Sun MY, Elalieh H, Fong C, Menendez AT, Wang Y, Vilardaga JP, Bikle DD. Regulation of Ligand and Shear Stress-induced Insulin-like Growth Factor 1 (IGF1) Signaling by the Integrin Pathway. The Journal of Biological Chemistry. PMID 26865633 DOI: 10.1074/Jbc.M115.693598 |
0.431 |
|
| 2015 |
Cheloha RW, Gellman SH, Vilardaga JP, Gardella TJ. PTH receptor-1 signalling-mechanistic insights and therapeutic prospects. Nature Reviews. Endocrinology. PMID 26303600 DOI: 10.1038/Nrendo.2015.139 |
0.647 |
|
| 2015 |
Gardella TJ, Vilardaga JP. International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors. Pharmacological Reviews. 67: 310-37. PMID 25713287 DOI: 10.1124/Pr.114.009464 |
0.579 |
|
| 2014 |
Vilardaga JP, Jean-Alphonse FG, Gardella TJ. Endosomal generation of cAMP in GPCR signaling. Nature Chemical Biology. 10: 700-6. PMID 25271346 DOI: 10.1038/Nchembio.1611 |
0.578 |
|
| 2014 |
Fernández-Dueñas V, Gómez-Soler M, López-Cano M, Taura JJ, Ledent C, Watanabe M, Jacobson KA, Vilardaga JP, Ciruela F. Uncovering caffeine's adenosine A2A receptor inverse agonism in experimental parkinsonism. Acs Chemical Biology. 9: 2496-501. PMID 25268872 DOI: 10.1021/Cb5005383 |
0.42 |
|
| 2014 |
Gidon A, Al-Bataineh MM, Jean-Alphonse FG, Stevenson HP, Watanabe T, Louet C, Khatri A, Calero G, Pastor-Soler NM, Gardella TJ, Vilardaga JP. Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase. Nature Chemical Biology. 10: 707-9. PMID 25064832 DOI: 10.1038/Nchembio.1589 |
0.635 |
|
| 2013 |
Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD, Hallows KR, Brown D, Bouley R, Vilardaga JP. Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. The Journal of Biological Chemistry. 288: 27849-60. PMID 23935101 DOI: 10.1074/Jbc.M112.445098 |
0.624 |
|
| 2013 |
Vilardaga JP, Romero G, Feinstein TN, Wehbi VL. Kinetics and dynamics in the G protein-coupled receptor signaling cascade. Methods in Enzymology. 522: 337-63. PMID 23374192 DOI: 10.1016/B978-0-12-407865-9.00016-9 |
0.616 |
|
| 2013 |
Wehbi VL, Stevenson HP, Feinstein TN, Calero G, Romero G, Vilardaga JP. Noncanonical GPCR signaling arising from a PTH receptor-arrestin-Gβγ complex. Proceedings of the National Academy of Sciences of the United States of America. 110: 1530-5. PMID 23297229 DOI: 10.1073/Pnas.1205756110 |
0.675 |
|
| 2012 |
Vilardaga JP, Gardella TJ, Wehbi VL, Feinstein TN. Non-canonical signaling of the PTH receptor. Trends in Pharmacological Sciences. 33: 423-31. PMID 22709554 DOI: 10.1016/J.Tips.2012.05.004 |
0.646 |
|
| 2012 |
Hanyu R, Wehbi VL, Hayata T, Moriya S, Feinstein TN, Ezura Y, Nagao M, Saita Y, Hemmi H, Notomi T, Nakamoto T, Schipani E, Takeda S, Kaneko K, Kurosawa H, ... ... Vilardaga JP, et al. Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 7433-8. PMID 22538810 DOI: 10.1073/Pnas.1109036109 |
0.498 |
|
| 2012 |
Wehbi VL, Stevenson HP, Feinstein TN, Romero G, Calero G, Vilardaga J. Dynamic Formation of a Ternary PTH Receptor-Arrestin-GS Complex: Consequences for Cell Signaling Biophysical Journal. 102: 240a. DOI: 10.1016/J.Bpj.2011.11.1322 |
0.685 |
|
| 2011 |
Nagao M, Feinstein TN, Ezura Y, Hayata T, Notomi T, Saita Y, Hanyu R, Hemmi H, Izu Y, Takeda S, Wang K, Rittling S, Nakamoto T, Kaneko K, Kurosawa H, ... ... Vilardaga JP, et al. Sympathetic control of bone mass regulated by osteopontin. Proceedings of the National Academy of Sciences of the United States of America. 108: 17767-72. PMID 21990347 DOI: 10.1073/Pnas.1109402108 |
0.36 |
|
| 2011 |
Liu Z, Turan S, Wehbi VL, Vilardaga JP, Bastepe M. Extra-long Gαs variant XLαs protein escapes activation-induced subcellular redistribution and is able to provide sustained signaling. The Journal of Biological Chemistry. 286: 38558-69. PMID 21890629 DOI: 10.1074/Jbc.M111.240150 |
0.507 |
|
| 2011 |
Vilardaga JP. Studying ligand efficacy at G protein-coupled receptors using FRET. Methods in Molecular Biology (Clifton, N.J.). 756: 133-48. PMID 21870223 DOI: 10.1007/978-1-61779-160-4_6 |
0.656 |
|
| 2011 |
Ardura JA, Wang B, Watkins SC, Vilardaga JP, Friedman PA. Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains. The Journal of Biological Chemistry. 286: 35020-9. PMID 21832055 DOI: 10.1074/Jbc.M111.264978 |
0.647 |
|
| 2011 |
Chen S, Webber MJ, Vilardaga JP, Khatri A, Brown D, Ausiello DA, Lin HY, Bouley R. Visualizing microtubule-dependent vasopressin type 2 receptor trafficking using a new high-affinity fluorescent vasopressin ligand. Endocrinology. 152: 3893-904. PMID 21828182 DOI: 10.1210/En.2011-1049 |
0.515 |
|
| 2011 |
Vilardaga JP. Recording kinetics of adrenergic receptor activation in live cells. Current Topics in Membranes. 67: 101-11. PMID 21771487 DOI: 10.1016/B978-0-12-384921-2.00005-7 |
0.681 |
|
| 2011 |
Feinstein TN, Wehbi VL, Ardura JA, Wheeler DS, Ferrandon S, Gardella TJ, Vilardaga JP. Retromer terminates the generation of cAMP by internalized PTH receptors. Nature Chemical Biology. 7: 278-84. PMID 21445058 DOI: 10.1038/Nchembio.545 |
0.647 |
|
| 2011 |
Vilardaga JP, Romero G, Friedman PA, Gardella TJ. Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. Cellular and Molecular Life Sciences : Cmls. 68: 1-13. PMID 20703892 DOI: 10.1007/S00018-010-0465-9 |
0.637 |
|
| 2010 |
Vilardaga JP, Agnati LF, Fuxe K, Ciruela F. G-protein-coupled receptor heteromer dynamics. Journal of Cell Science. 123: 4215-20. PMID 21123619 DOI: 10.1242/Jcs.063354 |
0.693 |
|
| 2010 |
Vilardaga JP. Theme and variations on kinetics of GPCR activation/deactivation. Journal of Receptor and Signal Transduction Research. 30: 304-12. PMID 20836728 DOI: 10.3109/10799893.2010.509728 |
0.594 |
|
| 2010 |
Klenk C, Vetter T, Zürn A, Vilardaga JP, Friedman PA, Wang B, Lohse MJ. Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor. The Journal of Biological Chemistry. 285: 30355-62. PMID 20656684 DOI: 10.1074/Jbc.M110.114900 |
0.761 |
|
| 2010 |
Ciruela F, Vilardaga JP, Fernández-Dueñas V. Lighting up multiprotein complexes: lessons from GPCR oligomerization. Trends in Biotechnology. 28: 407-15. PMID 20542584 DOI: 10.1016/J.Tibtech.2010.05.002 |
0.512 |
|
| 2010 |
Agnati LF, Guidolin D, Vilardaga JP, Ciruela F, Fuxe K. On the expanding terminology in the GPCR field: the meaning of receptor mosaics and receptor heteromers. Journal of Receptor and Signal Transduction Research. 30: 287-303. PMID 20429829 DOI: 10.3109/10799891003786226 |
0.584 |
|
| 2010 |
Ardura JA, Vilardaga J, Friedman PA. Protein-Exchange Dynamics at GPCR Micro-Domains: a Case Study with the Parathyroid Hormone Receptor Biophysical Journal. 98: 432a. DOI: 10.1016/J.Bpj.2009.12.2346 |
0.532 |
|
| 2009 |
Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP. Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nature Chemical Biology. 5: 734-42. PMID 19701185 DOI: 10.1038/Nchembio.206 |
0.597 |
|
| 2009 |
Kawada K, Upadhyay G, Ferandon S, Janarthanan S, Hall M, Vilardaga JP, Yajnik V. Cell migration is regulated by platelet-derived growth factor receptor endocytosis. Molecular and Cellular Biology. 29: 4508-18. PMID 19528233 DOI: 10.1128/Mcb.00015-09 |
0.575 |
|
| 2009 |
Brea J, Castro M, Giraldo J, López-Giménez JF, Padín JF, Quintián F, Cadavid MI, Vilaró MT, Mengod G, Berg KA, Clarke WP, Vilardaga JP, Milligan G, Loza MI. Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers. Molecular Pharmacology. 75: 1380-91. PMID 19279328 DOI: 10.1124/mol.108.054395 |
0.478 |
|
| 2009 |
Vilardaga JP, Bünemann M, Feinstein TN, Lambert N, Nikolaev VO, Engelhardt S, Lohse MJ, Hoffmann C. GPCR and G proteins: drug efficacy and activation in live cells. Molecular Endocrinology (Baltimore, Md.). 23: 590-9. PMID 19196832 DOI: 10.1210/Me.2008-0204 |
0.823 |
|
| 2009 |
Zürn A, Zabel U, Vilardaga JP, Schindelin H, Lohse MJ, Hoffmann C. Fluorescence resonance energy transfer analysis of alpha 2a-adrenergic receptor activation reveals distinct agonist-specific conformational changes. Molecular Pharmacology. 75: 534-41. PMID 19106230 DOI: 10.1124/Mol.108.052399 |
0.705 |
|
| 2008 |
Okazaki M, Ferrandon S, Vilardaga JP, Bouxsein ML, Potts JT, Gardella TJ. Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proceedings of the National Academy of Sciences of the United States of America. 105: 16525-30. PMID 18946036 DOI: 10.1073/Pnas.0808750105 |
0.492 |
|
| 2008 |
Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA. Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney International. 74: 1557-67. PMID 18813286 DOI: 10.1038/Ki.2008.412 |
0.575 |
|
| 2008 |
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bünemann M. Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends in Pharmacological Sciences. 29: 159-65. PMID 18262662 DOI: 10.1016/J.Tips.2007.12.002 |
0.82 |
|
| 2008 |
Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Kinetics of G-protein-coupled receptor signals in intact cells. British Journal of Pharmacology. 153: S125-32. PMID 18193071 DOI: 10.1038/sj.bjp.0707656 |
0.798 |
|
| 2008 |
Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nature Chemical Biology. 4: 126-31. PMID 18193048 DOI: 10.1038/Nchembio.64 |
0.807 |
|
| 2008 |
Dean T, Vilardaga JP, Potts JT, Gardella TJ. Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor. Molecular Endocrinology (Baltimore, Md.). 22: 156-66. PMID 17872377 DOI: 10.1210/Me.2007-0274 |
0.583 |
|
| 2008 |
Okazaki M, Ferrandon S, Vilardaga JP, Bouxsein ML, Potts JT, Gardella TJ. Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation (Proceedings of the National Academy of Sciences of the United States of America (October 28, 2008) 105: 43 10.1073/pnas.0808750105) Proceedings of the National Academy of Sciences of the United States of America. 105: 20559. DOI: 10.1073/pnas.0811217106 |
0.435 |
|
| 2007 |
Lohse MJ, Bünemann M, Hoffmann C, Vilardaga JP, Nikolaev VO. Monitoring receptor signaling by intramolecular FRET. Current Opinion in Pharmacology. 7: 547-53. PMID 17919975 DOI: 10.1016/J.Coph.2007.08.007 |
0.804 |
|
| 2007 |
Lohse MJ, Hoffmann C, Nikolaev VO, Vilardaga JP, Bünemann M. Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells. Advances in Protein Chemistry. 74: 167-88. PMID 17854658 DOI: 10.1016/S0065-3233(07)74005-6 |
0.83 |
|
| 2007 |
Rochais F, Vilardaga JP, Nikolaev VO, Bünemann M, Lohse MJ, Engelhardt S. Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. The Journal of Clinical Investigation. 117: 229-35. PMID 17200720 DOI: 10.1172/Jci30012 |
0.759 |
|
| 2006 |
Vilardaga JP. Switching modes for G protein-coupled receptor activation. Nature Chemical Biology. 2: 395-6. PMID 16850011 DOI: 10.1038/Nchembio0806-395 |
0.629 |
|
| 2006 |
Nikolaev VO, Hoffmann C, Bünemann M, Lohse MJ, Vilardaga JP. Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer. The Journal of Biological Chemistry. 281: 24506-11. PMID 16787921 DOI: 10.1074/Jbc.M603266200 |
0.837 |
|
| 2005 |
Vilardaga JP, Steinmeyer R, Harms GS, Lohse MJ. Molecular basis of inverse agonism in a G protein-coupled receptor. Nature Chemical Biology. 1: 25-8. PMID 16407989 DOI: 10.1038/Nchembio705 |
0.762 |
|
| 2005 |
Castro M, Nikolaev VO, Palm D, Lohse MJ, Vilardaga JP. Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism. Proceedings of the National Academy of Sciences of the United States of America. 102: 16084-9. PMID 16236727 DOI: 10.1073/Pnas.0503942102 |
0.762 |
|
| 2005 |
Hoffmann C, Gaietta G, Bünemann M, Adams SR, Oberdorff-Maass S, Behr B, Vilardaga JP, Tsien RY, Ellisman MH, Lohse MJ. A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nature Methods. 2: 171-6. PMID 15782185 DOI: 10.1038/Nmeth742 |
0.762 |
|
| 2004 |
Krasel C, Vilardaga JP, Bünemann M, Lohse MJ. Kinetics of G-protein-coupled receptor signalling and desensitization. Biochemical Society Transactions. 32: 1029-31. PMID 15506955 DOI: 10.1042/Bst0321029 |
0.825 |
|
| 2003 |
Lohse MJ, Vilardaga JP, Bünemann M. Molecular mechanisms of receptor activation: real-time analysis by fluorescence resonance energy transfer. Autonomic & Autacoid Pharmacology. 23: 231-3. PMID 15134067 |
0.726 |
|
| 2003 |
Lohse MJ, Vilardaga JP, Bünemann M. Direct optical recording of intrinsic efficacy at a G protein-coupled receptor. Life Sciences. 74: 397-404. PMID 14607268 DOI: 10.1016/J.Lfs.2003.09.026 |
0.823 |
|
| 2003 |
Vilardaga JP, Bünemann M, Krasel C, Castro M, Lohse MJ. Measurement of the millisecond activation switch of G protein-coupled receptors in living cells. Nature Biotechnology. 21: 807-12. PMID 12808462 DOI: 10.1038/Nbt838 |
0.809 |
|
| 2002 |
Castro M, Dicker F, Vilardaga JP, Krasel C, Bernhardt M, Lohse MJ. Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and beta-arrestins. Endocrinology. 143: 3854-65. PMID 12239097 DOI: 10.1210/En.2002-220232 |
0.651 |
|
| 2002 |
Vilardaga JP, Krasel C, Chauvin S, Bambino T, Lohse MJ, Nissenson RA. Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association. The Journal of Biological Chemistry. 277: 8121-9. PMID 11726668 DOI: 10.1074/Jbc.M110433200 |
0.669 |
|
| 2001 |
Vilardaga JP, Lin I, Nissenson RA. Analysis of parathyroid hormone (PTH)/secretin receptor chimeras differentiates the role of functional domains in the pth/ pth-related peptide (PTHrP) receptor on hormone binding and receptor activation. Molecular Endocrinology (Baltimore, Md.). 15: 1186-99. PMID 11435617 DOI: 10.1210/Mend.15.7.0665 |
0.519 |
|
| 2001 |
Vilardaga JP, Frank M, Krasel C, Dees C, Nissenson RA, Lohse MJ. Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein. The Journal of Biological Chemistry. 276: 33435-43. PMID 11387315 DOI: 10.1074/Jbc.M011495200 |
0.699 |
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| 1999 |
Di Paolo E, Vilardaga JP, Petry H, Moguilevsky N, Bollen A, Robberecht P, Waelbroeck M. Role of charged amino acids conserved in the vasoactive intestinal polypeptide/secretin family of receptors on the secretin receptor functionality. Peptides. 20: 1187-93. PMID 10573290 DOI: 10.1016/S0196-9781(99)00122-9 |
0.4 |
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| 1997 |
Vilardaga JP, Di Paolo E, Bialek C, De Neef P, Waelbroeck M, Bollen A, Robberecht P. Mutational analysis of extracellular cysteine residues of rat secretin receptor shows that disulfide bridges are essential for receptor function. European Journal of Biochemistry / Febs. 246: 173-80. PMID 9210480 DOI: 10.1111/J.1432-1033.1997.00173.X |
0.428 |
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| 1997 |
Vilardaga JP, Ujlaml L, Nissenson RA. Structure-function analysis of pth receptor, a class ii g protein-coupled receptor Faseb Journal. 11: A1332. |
0.521 |
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| 1996 |
Gourlet P, Vilardaga JP, De Neef P, Waelbroeck M, Vandermeers A, Robberecht P. The C-terminus ends of secretin and VIP interact with the N-terminal domains of their receptors. Peptides. 17: 825-9. PMID 8844773 DOI: 10.1016/0196-9781(96)00107-6 |
0.539 |
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| 1996 |
Gourlet P, Vilardaga JP, De Neef P, Vandermeers A, Waelbroeck M, Bollen A, Robberecht P. Interaction of amino acid residues at positions 8-15 of secretin with the N-terminal domain of the secretin receptor. European Journal of Biochemistry / Febs. 239: 349-55. PMID 8706739 DOI: 10.1111/J.1432-1033.1996.0349U.X |
0.52 |
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| 1996 |
Vilardaga JP, di Paolo E, de Neef P, Waelbroeck M, Bollen A, Robberecht P. Lysine 173 residue within the first exoloop of rat secretin receptor is involved in carboxylate moiety recognition of Asp 3 in secretin. Biochemical and Biophysical Research Communications. 218: 842-6. PMID 8579602 DOI: 10.1006/bbrc.1996.0150 |
0.483 |
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| 1995 |
Ciccarelli E, Svoboda M, De Neef P, Di Paolo E, Bollen A, Dubeaux C, Vilardaga JP, Waelbroeck M, Robberecht P. Pharmacological properties of two recombinant splice variants of the PACAP type I receptor, transfected and stably expressed in CHO cells. European Journal of Pharmacology. 288: 259-67. PMID 7774670 DOI: 10.1016/0922-4106(95)90037-3 |
0.589 |
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| 1995 |
Vilardaga JP, De Neef P, Di Paolo E, Bollen A, Waelbroeck M, Robberecht P. Properties of chimeric secretin and VIP receptor proteins indicate the importance of the N-terminal domain for ligand discrimination. Biochemical and Biophysical Research Communications. 211: 885-91. PMID 7598719 DOI: 10.1006/bbrc.1995.1895 |
0.453 |
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| 1994 |
Vilardaga JP, Ciccarelli E, Dubeaux C, De Neef P, Bollen A, Robberecht P. Properties and regulation of the coupling to adenylate cyclase of secretin receptors stably transfected in Chinese hamster ovary cells. Molecular Pharmacology. 45: 1022-8. PMID 8190092 |
0.396 |
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| 1994 |
Ciccarelli E, Vilardaga JP, De Neef P, Di Paolo E, Waelbroeck M, Bollen A, Robberecht P. Properties of the VIP-PACAP type II receptor stably expressed in CHO cells. Regulatory Peptides. 54: 397-407. PMID 7716273 DOI: 10.1016/0167-0115(94)90537-1 |
0.528 |
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| Low-probability matches (unlikely to be authored by this person) |
| 2017 |
Bhattacharyya S, Jean-Alphonse FG, Raghavan V, McGarvey JC, Rbaibi Y, Vilardaga JP, Carattino MD, Weisz OA. Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells. Physiological Reports. 5. PMID 29038362 DOI: 10.14814/Phy2.13460 |
0.293 |
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| 2020 |
Chang W, Tu CL, Jean-Alphonse FG, Herberger A, Cheng Z, Hwong J, Ho H, Li A, Wang D, Liu H, White AD, Suh I, Shen W, Duh QY, Khanafshar E, ... ... Vilardaga JP, et al. PTH hypersecretion triggered by a GABA and Ca-sensing receptor heterocomplex in hyperparathyroidism. Nature Metabolism. 2: 243-255. PMID 32694772 DOI: 10.1038/s42255-020-0175-z |
0.288 |
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| 2013 |
Leslie KL, Song GJ, Barrick S, Wehbi VL, Vilardaga JP, Bauer PM, Bisello A. Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-κB (NF-κB): a feed-forward loop for systemic and vascular inflammation. The Journal of Biological Chemistry. 288: 36426-36. PMID 24196963 DOI: 10.1074/Jbc.M113.483339 |
0.259 |
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| 2015 |
Xu Y, Streets AJ, Hounslow AM, Tran U, Jean-Alphonse F, Needham AJ, Vilardaga JP, Wessely O, Williamson MP, Ong AC. The Polycystin-1, Lipoxygenase, and α-Toxin Domain Regulates Polycystin-1 Trafficking. Journal of the American Society of Nephrology : Jasn. PMID 26311459 DOI: 10.1681/Asn.2014111074 |
0.151 |
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| 2015 |
Twohig MP, Vilardaga JCP, Levin ME, Hayes SC. Changes in psychological flexibility during acceptance and commitment therapy for obsessive compulsive disorder Journal of Contextual Behavioral Science. 4: 196-202. DOI: 10.1016/J.Jcbs.2015.07.001 |
0.061 |
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| 2016 |
Stevenson HP, Lin G, Barnes CO, Sutkeviciute I, Krzysiak T, Weiss SC, Reynolds S, Wu Y, Nagarajan V, Makhov AM, Lawrence R, Lamm E, Clark L, Gardella TJ, Hogue BG, ... ... Vilardaga JP, et al. Transmission electron microscopy for the evaluation and optimization of crystal growth. Acta Crystallographica. Section D, Structural Biology. 72: 603-615. PMID 27139624 DOI: 10.1107/S2059798316001546 |
0.038 |
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| 2013 |
Luoma JB, Vilardaga JP. Improving therapist psychological flexibility while training acceptance and commitment therapy: a pilot study. Cognitive Behaviour Therapy. 42: 1-8. PMID 23505991 DOI: 10.1080/16506073.2012.701662 |
0.036 |
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| 2013 |
Chase JA, Houmanfar R, Hayes SC, Ward TA, Vilardaga JP, Follette V. Values are not just goals: Online ACT-based values training adds to goal setting in improving undergraduate college student performance Journal of Contextual Behavioral Science. 2: 79-84. DOI: 10.1016/J.Jcbs.2013.08.002 |
0.016 |
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| 1995 |
Vilardaga JP, Di Paolo E, Bollen A. Improved PCR method for high-efficiency site-directed mutagenesis using class 2S restriction enzymes. Biotechniques. 18: 604-6. PMID 7598888 |
0.012 |
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| 2014 |
Craske MG, Niles AN, Burklund LJ, Wolitzky-Taylor KB, Vilardaga JC, Arch JJ, Saxbe DE, Lieberman MD. Randomized controlled trial of cognitive behavioral therapy and acceptance and commitment therapy for social phobia: outcomes and moderators. Journal of Consulting and Clinical Psychology. 82: 1034-48. PMID 24999670 DOI: 10.1037/A0037212 |
0.012 |
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| 2007 |
Sánchez XF, Farfan EG, Vilardaga JN. Two-stage revision of septic hip prosthesis with uncemented implants Infection and Local Treatment in Orthopedic Surgery. 214-230. DOI: 10.1007/978-3-540-47999-4_26 |
0.01 |
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| Hide low-probability matches. |