Matthew P. Patricelli, Ph.D. - Publications

2001 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Medicinal Chemistry

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Janes MR, Zhang J, Li LS, Hansen R, Peters U, Guo X, Chen Y, Babbar A, Firdaus SJ, Darjania L, Feng J, Chen JH, Li S, Li S, Long YO, ... ... Patricelli MP, et al. Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 172: 578-589.e17. PMID 29373830 DOI: 10.1016/j.cell.2018.01.006  0.36
2017 Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. Plos One. 12: e0172649. PMID 28199383 DOI: 10.1371/journal.pone.0172649  0.44
2016 Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. Plos One. 11: e0152934. PMID 27031502 DOI: 10.1371/journal.pone.0152934  0.88
2016 Patricelli MP, Janes MR, Li LS, Hansen R, Peters U, Kessler LV, Chen Y, Kucharski JM, Feng J, Ely T, Chen JH, Firdaus SJ, Babbar A, Ren P, Liu Y. Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State. Cancer Discovery. PMID 26739882 DOI: 10.1158/2159-8290.CD-15-1105  0.88
2015 Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, et al. Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2). Journal of Medicinal Chemistry. 58: 183-96. PMID 25075558 DOI: 10.1021/jm500480k  0.88
2014 Okerberg ES, Brown HE, Minimo L, Alemayehu S, Rosenblum J, Patricelli M, Nomanbhoy T, Kozarich JW. Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe. Journal of the American Chemical Society. 136: 4664-9. PMID 24601623 DOI: 10.1021/ja4129907  0.88
2014 Atkins C, Evans CW, Nordin B, Patricelli MP, Reynolds R, Wennerberg K, Noah JW. Global Human-Kinase Screening Identifies Therapeutic Host Targets against Influenza. Journal of Biomolecular Screening. 19: 936-946. PMID 24464431 DOI: 10.1177/1087057113518068  0.88
2013 Villamor JG, Kaschani F, Colby T, Oeljeklaus J, Zhao D, Kaiser M, Patricelli MP, van der Hoorn RA. Profiling protein kinases and other ATP binding proteins in Arabidopsis using Acyl-ATP probes. Molecular & Cellular Proteomics : McP. 12: 2481-96. PMID 23722185 DOI: 10.1074/mcp.M112.026278  0.88
2013 Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, et al. Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR. Cancer Research. 73: 2574-86. PMID 23436801 DOI: 10.1158/0008-5472.CAN-12-1702  0.88
2012 Choi HG, Zhang J, Deng X, Hatcher JM, Patricelli MP, Zhao Z, Alessi DR, Gray NS. Brain Penetrant LRRK2 Inhibitor. Acs Medicinal Chemistry Letters. 3: 658-662. PMID 23066449 DOI: 10.1021/ml300123a  0.88
2012 Vetter ML, Rodgers MA, Patricelli MP, Yang PL. Chemoproteomic profiling identifies changes in DNA-PK as markers of early dengue virus infection. Acs Chemical Biology. 7: 2019-26. PMID 22999307 DOI: 10.1021/cb300420z  0.88
2012 Dix MM, Simon GM, Wang C, Okerberg E, Patricelli MP, Cravatt BF. Functional interplay between caspase cleavage and phosphorylation sculpts the apoptotic proteome. Cell. 150: 426-40. PMID 22817901 DOI: 10.1016/j.cell.2012.05.040  0.88
2012 Zhang T, Inesta-Vaquera F, Niepel M, Zhang J, Ficarro SB, Machleidt T, Xie T, Marto JA, Kim N, Sim T, Laughlin JD, Park H, LoGrasso PV, Patricelli M, Nomanbhoy TK, et al. Discovery of potent and selective covalent inhibitors of JNK. Chemistry & Biology. 19: 140-54. PMID 22284361 DOI: 10.1016/j.chembiol.2011.11.010  0.88
2012 Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, et al. Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics. The Journal of Biological Chemistry. 287: 9742-52. PMID 22223645 DOI: 10.1074/jbc.M111.304485  0.88
2011 Patricelli MP, Nomanbhoy TK, Wu J, Brown H, Zhou D, Zhang J, Jagannathan S, Aban A, Okerberg E, Herring C, Nordin B, Weissig H, Yang Q, Lee JD, Gray NS, et al. In situ kinase profiling reveals functionally relevant properties of native kinases. Chemistry & Biology. 18: 699-710. PMID 21700206 DOI: 10.1016/j.chembiol.2011.04.011  0.88
2011 Chou TF, Brown SJ, Minond D, Nordin BE, Li K, Jones AC, Chase P, Porubsky PR, Stoltz BM, Schoenen FJ, Patricelli MP, Hodder P, Rosen H, Deshaies RJ. Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 4834-9. PMID 21383145 DOI: 10.1073/pnas.1015312108  0.88
2011 Deng X, Dzamko N, Prescott A, Davies P, Liu Q, Yang Q, Lee JD, Patricelli MP, Nomanbhoy TK, Alessi DR, Gray NS. Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2. Nature Chemical Biology. 7: 203-5. PMID 21378983 DOI: 10.1038/nchembio.538  0.88
2010 Yang Q, Deng X, Lu B, Cameron M, Fearns C, Patricelli MP, Yates JR, Gray NS, Lee JD. Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein. Cancer Cell. 18: 258-67. PMID 20832753 DOI: 10.1016/j.ccr.2010.08.008  0.88
2010 Miyazaki M, Nakagawa I, Koga S, Kasahara Y, Patricelli MP. Proteomics analysis of cardiac muscle from rats with peroxisomal proliferator-activated receptor alpha (PPARalpha) stimulation. The Journal of Toxicological Sciences. 35: 131-5. PMID 20118634 DOI: 10.2131/jts.35.131  0.88
2009 Miyazaki M, Rosenblum JS, Kasahara Y, Nakagawa I, Patricelli MP. Determination of enzymatic source of alanine aminotransferase activity in serum from dogs with liver injury. Journal of Pharmacological and Toxicological Methods. 60: 307-15. PMID 19748590 DOI: 10.1016/j.vascn.2009.09.001  0.88
2008 Liu Y, Wu J, Weissig H, Betancort JM, Gai WZ, Leventhal PS, Patricelli MP, Samii B, Szardenings AK, Shreder KR, Kozarich JW. Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta. Bioorganic & Medicinal Chemistry Letters. 18: 5955-8. PMID 18774710 DOI: 10.1016/j.bmcl.2008.08.045  0.88
2007 Patricelli MP, Szardenings AK, Liyanage M, Nomanbhoy TK, Wu M, Weissig H, Aban A, Chun D, Tanner S, Kozarich JW. Functional interrogation of the kinome using nucleotide acyl phosphates. Biochemistry. 46: 350-8. PMID 17209545 DOI: 10.1021/bi062142x  0.88
2005 Okerberg ES, Wu J, Zhang B, Samii B, Blackford K, Winn DT, Shreder KR, Burbaum JJ, Patricelli MP. High-resolution functional proteomics by active-site peptide profiling. Proceedings of the National Academy of Sciences of the United States of America. 102: 4996-5001. PMID 15795380 DOI: 10.1073/pnas.0501205102  0.88
2005 Jessani N, Young JA, Diaz SL, Patricelli MP, Varki A, Cravatt BF. Class assignment of sequence-unrelated members of enzyme superfamilies by activity-based protein profiling. Angewandte Chemie (International Ed. in English). 44: 2400-3. PMID 15765498 DOI: 10.1002/anie.200463098  0.88
2004 Adam GC, Burbaum J, Kozarich JW, Patricelli MP, Cravatt BF. Mapping enzyme active sites in complex proteomes. Journal of the American Chemical Society. 126: 1363-8. PMID 14759193 DOI: 10.1021/ja038441g  0.88
2002 Patricelli MP. Activity-based probes for functional proteomics. Briefings in Functional Genomics & Proteomics. 1: 151-8. PMID 15239901 DOI: 10.1093/bfgp/1.2.151  0.88
2001 Patricelli MP, Giang DK, Stamp LM, Burbaum JJ. Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes. Proteomics. 1: 1067-71. PMID 11990500 DOI: 10.1002/1615-9861(200109)1:9<1067::AID-PROT1067>3.0.CO;2-4  0.88
2001 Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 98: 9371-6. PMID 11470906 DOI: 10.1073/pnas.161191698  0.88
2001 Patricelli MP, Cravatt BF. Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase. Biochemistry. 40: 6107-15. PMID 11352748 DOI: 10.1021/bi002578r  0.88
2001 Patricelli MP, Cravatt BF. Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides. Vitamins and Hormones. 62: 95-131. PMID 11345902  0.88
2000 Boger DL, Fecik RA, Patterson JE, Miyauchi H, Patricelli MP, Cravatt BF. Fatty acid amide hydrolase substrate specificity. Bioorganic & Medicinal Chemistry Letters. 10: 2613-6. PMID 11128635 DOI: 10.1016/S0960-894X(00)00528-X  0.88
2000 Boger DL, Sato H, Lerner AE, Hedrick MP, Fecik RA, Miyauchi H, Wilkie GD, Austin BJ, Patricelli MP, Cravatt BF. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. Proceedings of the National Academy of Sciences of the United States of America. 97: 5044-9. PMID 10805767 DOI: 10.1073/pnas.97.10.5044  0.88
2000 Patricelli MP, Cravatt BF. Clarifying the catalytic roles of conserved residues in the amidase signature family. The Journal of Biological Chemistry. 275: 19177-84. PMID 10764768 DOI: 10.1074/jbc.M001607200  0.88
1999 Liu Y, Patricelli MP, Cravatt BF. Activity-based protein profiling: the serine hydrolases. Proceedings of the National Academy of Sciences of the United States of America. 96: 14694-9. PMID 10611275 DOI: 10.1073/pnas.96.26.14694  0.88
1999 Patricelli MP, Cravatt BF. Fatty acid amide hydrolase competitively degrades bioactive amides and esters through a nonconventional catalytic mechanism. Biochemistry. 38: 14125-30. PMID 10571985 DOI: 10.1021/bi991876p  0.88
1999 Patricelli MP, Lovato MA, Cravatt BF. Chemical and mutagenic investigations of fatty acid amide hydrolase: evidence for a family of serine hydrolases with distinct catalytic properties. Biochemistry. 38: 9804-12. PMID 10433686 DOI: 10.1021/bi990637z  0.88
1999 Boger DL, Sato H, Lerner AE, Austin BJ, Patterson JE, Patricelli MP, Cravatt BF. Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: a probe of structural and conformational features contributing to inhibition. Bioorganic & Medicinal Chemistry Letters. 9: 265-70. PMID 10021942 DOI: 10.1016/S0960-894X(98)00734-3  0.88
1998 Patricelli MP, Patterson JE, Boger DL, Cravatt BF. An endogenous sleep-inducing compound is a novel competitive inhibitor of fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters. 8: 613-8. PMID 9871570 DOI: 10.1016/S0960-894X(98)00073-0  0.88
1998 Patricelli MP, Lashuel HA, Giang DK, Kelly JW, Cravatt BF. Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: identification of the transmembrane domain as a site for oligomerization. Biochemistry. 37: 15177-87. PMID 9790682 DOI: 10.1021/bi981733n  0.88
1997 DiFalco MR, Bakopanos E, Patricelli M, Chan G, Congote LF. The influence of various insect cell lines, p10 and polyhedrin promoters in the production of secreted insulin-like growth factor-interleukin-3 chimeras in the baculovirus expression system Journal of Biotechnology. 56: 49-56. PMID 9246791 DOI: 10.1016/S0168-1656(97)00077-1  0.88
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