Jae W. Chang, Ph.D. - Publications

Affiliations: 
2013 Chemical Physiology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Medicinal Chemistry

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Huang JX, Lee G, Cavanaugh KE, Chang JW, Gardel ML, Moellering RE. High throughput discovery of functional protein modifications by Hotspot Thermal Profiling. Nature Methods. PMID 31384043 DOI: 10.1038/s41592-019-0499-3  0.8
2016 Jeon HJ, You SY, Park YS, Chang JW, Kim JS, Oh JS. TCTP regulates spindle microtubule dynamics by stabilizing polar microtubules during mouse oocyte meiosis. Biochimica Et Biophysica Acta. PMID 26802898 DOI: 10.1016/j.bbamcr.2016.01.012  0.4
2016 Guo J, Zhang H, Wang C, Chang JW, Chen LL. Construction and analysis of a genome-scale metabolic network for Bacillus licheniformis WX-02. Research in Microbiology. PMID 26776566 DOI: 10.1016/j.resmic.2015.12.005  0.4
2016 Buczynski MW, Herman MA, Hsu KL, Natividad LA, Irimia C, Polis IY, Pugh H, Chang JW, Niphakis MJ, Cravatt BF, Roberto M, Parsons LH. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755579 DOI: 10.1073/pnas.1522672113  0.8
2015 Chang JW, Hong HJ, Ban MJ, Shin YS, Kim WS, Koh YW, Choi EC. Prognostic Factors and Treatment Outcomes of Parotid Gland Cancer: A 10-Year Single-Center Experience. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. PMID 26203086 DOI: 10.1177/0194599815594789  0.8
2015 Kohnz RA, Mulvihill MM, Chang JW, Hsu KL, Sorrentino A, Cravatt BF, Bandyopadhyay S, Goga A, Nomura DK. Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. Acs Chemical Biology. 10: 1624-30. PMID 25945974 DOI: 10.1021/acschembio.5b00053  0.8
2015 Chang JW, Zuhl AM, Speers AE, Niessen S, Brown SJ, Mulvihill MM, Fan YC, Spicer TP, Southern M, Scampavia L, Fernandez-Vega V, Dix MM, Cameron MD, Hodder PS, Rosen H, et al. Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. Acs Chemical Biology. 10: 925-32. PMID 25602368 DOI: 10.1021/cb500893q  0.8
2015 Wang C, Deng ZL, Xie ZM, Chu XY, Chang JW, Kong DX, Li BJ, Zhang HY, Chen LL. Construction of a genome-scale metabolic network of the plant pathogen Pectobacterium carotovorum provides new strategies for bactericide discovery. Febs Letters. 589: 285-94. PMID 25535697 DOI: 10.1016/j.febslet.2014.12.010  0.4
2014 Galmozzi A, Sonne SB, Altshuler-Keylin S, Hasegawa Y, Shinoda K, Luijten IH, Chang JW, Sharp LZ, Cravatt BF, Saez E, Kajimura S. ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Reports. 9: 1584-93. PMID 25466254 DOI: 10.1016/j.celrep.2014.10.066  0.8
2014 Manna JD, Wepy JA, Hsu KL, Chang JW, Cravatt BF, Marnett LJ. Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. The Journal of Biological Chemistry. 289: 33741-53. PMID 25301951 DOI: 10.1074/jbc.M114.582353  0.8
2014 Dominguez E, Galmozzi A, Chang JW, Hsu KL, Pawlak J, Li W, Godio C, Thomas J, Partida D, Niessen S, O'Brien PE, Russell AP, Watt MJ, Nomura DK, Cravatt BF, et al. Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nature Chemical Biology. 10: 113-21. PMID 24362705 DOI: 10.1038/nchembio.1429  0.8
2013 Hsu KL, Tsuboi K, Chang JW, Whitby LR, Speers AE, Pugh H, Cravatt BF. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). Journal of Medicinal Chemistry. 56: 8270-9. PMID 24152295 DOI: 10.1021/jm400899c  0.8
2013 Holly SP, Chang JW, Li W, Niessen S, Phillips RM, Piatt R, Black JL, Smith MC, Boulaftali Y, Weyrich AS, Bergmeier W, Cravatt BF, Parise LV. Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation. Chemistry & Biology. 20: 1125-34. PMID 23993462 DOI: 10.1016/j.chembiol.2013.07.011  0.8
2013 Niphakis MJ, Cognetta AB, Chang JW, Buczynski MW, Parsons LH, Byrne F, Burston JJ, Chapman V, Cravatt BF. Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors. Acs Chemical Neuroscience. 4: 1322-32. PMID 23731016 DOI: 10.1021/cn400116z  0.8
2013 Chang JW, Cognetta AB, Niphakis MJ, Cravatt BF. Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition. Acs Chemical Biology. 8: 1590-9. PMID 23701408 DOI: 10.1021/cb400261h  0.8
2013 Bisogno T, Mahadevan A, Coccurello R, Chang JW, Allarà M, Chen Y, Giacovazzo G, Lichtman A, Cravatt B, Moles A, Di Marzo V. A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects British Journal of Pharmacology. 169: 784-793. PMID 23072382 DOI: 10.1111/bph.12013  0.8
2012 Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF. Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes. Journal of the American Chemical Society. 134: 10345-8. PMID 22690931 DOI: 10.1021/ja303400u  0.8
2012 Chang JW, Niphakis MJ, Lum KM, Cognetta AB, Wang C, Matthews ML, Niessen S, Buczynski MW, Parsons LH, Cravatt BF. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chemistry & Biology. 19: 579-88. PMID 22542104 DOI: 10.1016/j.chembiol.2012.03.009  0.8
2012 Chang JW, Moellering RE, Cravatt BF. An activity-based imaging probe for the integral membrane hydrolase KIAA1363. Angewandte Chemie (International Ed. in English). 51: 966-70. PMID 22162147 DOI: 10.1002/anie.201107236  0.8
2011 Nomura DK, Lombardi DP, Chang JW, Niessen S, Ward AM, Long JZ, Hoover HH, Cravatt BF. Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer. Chemistry & Biology. 18: 846-56. PMID 21802006 DOI: 10.1016/j.chembiol.2011.05.009  0.8
2011 Chang JW, Nomura DK, Cravatt BF. A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis. Chemistry & Biology. 18: 476-84. PMID 21513884 DOI: 10.1016/j.chembiol.2011.02.008  0.8
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