Jae W. Chang, Ph.D. - Publications

Affiliations: 
2013 Chemical Physiology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Medicinal Chemistry

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Jeon HJ, You SY, Park YS, Chang JW, Kim JS, Oh JS. TCTP regulates spindle microtubule dynamics by stabilizing polar microtubules during mouse oocyte meiosis. Biochimica Et Biophysica Acta. PMID 26802898 DOI: 10.1016/j.bbamcr.2016.01.012  0.4
2016 Guo J, Zhang H, Wang C, Chang JW, Chen LL. Construction and analysis of a genome-scale metabolic network for Bacillus licheniformis WX-02. Research in Microbiology. PMID 26776566 DOI: 10.1016/j.resmic.2015.12.005  0.4
2016 Buczynski MW, Herman MA, Hsu KL, Natividad LA, Irimia C, Polis IY, Pugh H, Chang JW, Niphakis MJ, Cravatt BF, Roberto M, Parsons LH. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755579 DOI: 10.1073/pnas.1522672113  0.8
2016 Park SE, Lee NK, Lee J, Hwang JW, Choi SJ, Hwang H, Hyung B, Chang JW, Na DL. Distribution of human umbilical cord blood-derived mesenchymal stem cells in the Alzheimer's disease transgenic mouse after a single intravenous injection. Neuroreport. PMID 26752148 DOI: 10.1097/WNR.0000000000000526  0.4
2016 Jeong da U, Oh JH, Lee JE, Lee J, Cho ZH, Chang JW, Chang WS. Basal Forebrain Cholinergic Deficits Reduce Glucose Metabolism and Function of Cholinergic and GABAergic Systems in the Cingulate Cortex. Yonsei Medical Journal. 57: 165-72. PMID 26632397 DOI: 10.3349/ymj.2016.57.1.165  0.4
2015 Cha HY, Lee BS, Chang JW, Park JK, Han JH, Kim YS, Shin YS, Byeon HK, Kim CH. Downregulation of nrf2 by the combination of TRAIL and valproic acid induces apoptotic cell death of TRAIL-resistant papillary thyroid cancer cells via suppression of bcl-xl. Cancer Letters. PMID 26721202 DOI: 10.1016/j.canlet.2015.12.016  0.4
2015 Chang JW, Kang SU, Shin YS, Seo SJ, Kim YS, Yang SS, Lee JS, Moon E, Lee K, Kim CH. Combination of NTP with cetuximab inhibited invasion/migration of cetuximab-resistant OSCC cells: Involvement of NF-κB signaling. Scientific Reports. 5: 18208. PMID 26655729 DOI: 10.1038/srep18208  0.4
2015 Jang CK, Jung HH, Chang JH, Chang JW, Park YG, Chang WS. Long-Term Results of Gamma Knife Radiosurgery for Intracranial Meningioma. Brain Tumor Research and Treatment. 3: 103-107. PMID 26605265 DOI: 10.14791/btrt.2015.3.2.103  0.4
2015 Chang JW, Gwak SY, Shim GA, Liu L, Lim YC, Kim JM, Jung MG, Koo BS. EZH2 is associated with poor prognosis in head-and-neck squamous cell carcinoma via regulating the epithelial-to-mesenchymal transition and chemosensitivity. Oral Oncology. PMID 26604082 DOI: 10.1016/j.oraloncology.2015.11.002  0.4
2015 Mandyam CD, Schilling JM, Cui W, Egawa J, Niesman IR, Kellerhals SE, Staples MC, Busija AR, Risbrough VB, Posadas E, Grogman GC, Chang JW, Roth DM, Patel PM, Patel HH, et al. Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice. Biological Psychiatry. PMID 26592463 DOI: 10.1016/j.biopsych.2015.09.020  0.4
2015 Byeon HK, Kim DH, Chang JW, Ban MJ, Park JH, Kim WS, Choi EC, Koh YW. Comprehensive application of robotic retroauricular thyroidectomy: The evolution of robotic thyroidectomy. The Laryngoscope. PMID 26525822 DOI: 10.1002/lary.25763  0.4
2015 Tseng RC, Chang JW, Mao JS, Tsai CD, Wu PC, Lin CJ, Lu YL, Liao SY, Cheng HC, Hsu HS, Wang YC. Growth-arrest-specific 7C protein inhibits tumor metastasis via the N-WASP/FAK/F-actin and hnRNP U/β-TrCP/β-catenin pathways in lung cancer. Oncotarget. PMID 26506240 DOI: 10.18632/oncotarget.6229  0.4
2015 Byeon HK, Na HJ, Yang YJ, Kwon HJ, Chang JW, Ban MJ, Kim WS, Shin DY, Lee EJ, Koh YW, Yoon JH, Choi EC. c-Met-mediated reactivation of PI3K/AKT signaling contributes to insensitivity of BRAF(V600E) mutant thyroid cancer to BRAF inhibition. Molecular Carcinogenesis. PMID 26456083 DOI: 10.1002/mc.22418  0.4
2015 Jo DS, Bae DJ, Park SJ, Seo HM, Kim HB, Oh JS, Chang JW, Kim SY, Shin JW, Cho DH. Pexophagy is induced by increasing peroxisomal reactive oxygen species in 1'10-phenanthroline-treated cells. Biochemical and Biophysical Research Communications. PMID 26453011 DOI: 10.1016/j.bbrc.2015.09.153  0.4
2015 Yang YJ, Na HJ, Suh MJ, Ban MJ, Byeon HK, Kim WS, Kim JW, Choi EC, Kwon HJ, Chang JW, Koh YW. Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α. Yonsei Medical Journal. 56: 1503-14. PMID 26446630 DOI: 10.3349/ymj.2015.56.6.1503  0.4
2015 Shih CL, Luo JD, Chang JW, Chen TL, Chien YT, Yu CJ, Chiou CC. Circulating Messenger RNA Profiling with Microarray and Next-generation Sequencing: Cross-platform Comparison. Cancer Genomics & Proteomics. 12: 223-230. PMID 26417025  0.4
2015 Chang WS, Jung HH, Zadicario E, Rachmilevitch I, Tlusty T, Vitek S, Chang JW. Factors associated with successful magnetic resonance-guided focused ultrasound treatment: efficiency of acoustic energy delivery through the skull. Journal of Neurosurgery. 1-6. PMID 26361280 DOI: 10.3171/2015.3.JNS142592  0.4
2015 Park HW, Moon HE, Kim HR, Paek SL, Kim Y, Chang JW, Yang YS, Kim K, Oh W, Hwang JH, Kim JW, Kim DG, Paek SH. Human umbilical cord blood-derived mesenchymal stem cells improve functional recovery through thrombospondin1, pantraxin3, and vascular endothelial growth factor in the ischemic rat brain. Journal of Neuroscience Research. PMID 26332684 DOI: 10.1002/jnr.23616  0.4
2015 Kim JH, Chang WS, Jung HH, Chang JW. Effect of Subthalamic Deep Brain Stimulation on Levodopa-Induced Dyskinesia in Parkinson's Disease. Yonsei Medical Journal. 56: 1316-21. PMID 26256974 DOI: 10.3349/ymj.2015.56.5.1316  0.4
2015 Han JS, Kim JK, Chang JW, Han JH. An improved quasi-steady aerodynamic model for insect wings that considers movement of the center of pressure. Bioinspiration & Biomimetics. 10: 046014. PMID 26226478 DOI: 10.1088/1748-3190/10/4/046014  0.4
2015 Chang JW, Hong HJ, Ban MJ, Shin YS, Kim WS, Koh YW, Choi EC. Prognostic Factors and Treatment Outcomes of Parotid Gland Cancer: A 10-Year Single-Center Experience. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. PMID 26203086 DOI: 10.1177/0194599815594789  0.8
2015 Kim K, Park HW, Moon HE, Kim JW, Bae S, Chang JW, Oh W, Yang YS, Paek SH. The Effect of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in a Collagenase-Induced Intracerebral Hemorrhage Rat Model. Experimental Neurobiology. 24: 146-55. PMID 26113794 DOI: 10.5607/en.2015.24.2.146  0.4
2015 Chang JW, Zhang W, Yeh HS, de Jong EP, Jun S, Kim KH, Bae SS, Beckman K, Hwang TH, Kim KS, Kim DH, Griffin TJ, Kuang R, Yong J. mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation. Nature Communications. 6: 7218. PMID 26074333 DOI: 10.1038/ncomms8218  0.4
2015 Chang JW, Hwang HS, Kim YS, Kim HJ, Shin YS, Jittreetat T, Kim CH. Protective effect of Artemisia asiatica (Pamp.) Nakai ex Kitam ethanol extract against cisplatin-induced apoptosis of human HaCaT keratinocytes: Involvement of NF-kappa B- and Bcl-2-controlled mitochondrial signaling. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 22: 679-88. PMID 26055133 DOI: 10.1016/j.phymed.2015.04.003  0.4
2015 Kohnz RA, Mulvihill MM, Chang JW, Hsu KL, Sorrentino A, Cravatt BF, Bandyopadhyay S, Goga A, Nomura DK. Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer. Acs Chemical Biology. 10: 1624-30. PMID 25945974 DOI: 10.1021/acschembio.5b00053  0.8
2015 Chang JW, Koh YW, Chung WY, Hong SW, Choi EC. Predictors of thyroid gland involvement in hypopharyngeal squamous cell carcinoma. Yonsei Medical Journal. 56: 812-8. PMID 25837190 DOI: 10.3349/ymj.2015.56.3.812  0.4
2015 Shin JH, Kim PS, Kim ES, Park SJ, Jo YK, Hwang JJ, Park TJ, Chang JW, Seo JH, Cho DH. BIX-01294-induced autophagy regulates elongation of primary cilia. Biochemical and Biophysical Research Communications. 460: 428-33. PMID 25796328 DOI: 10.1016/j.bbrc.2015.03.050  0.4
2015 Chang JW, Zuhl AM, Speers AE, Niessen S, Brown SJ, Mulvihill MM, Fan YC, Spicer TP, Southern M, Scampavia L, Fernandez-Vega V, Dix MM, Cameron MD, Hodder PS, Rosen H, et al. Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. Acs Chemical Biology. 10: 925-32. PMID 25602368 DOI: 10.1021/cb500893q  0.8
2015 Jang M, Shin YS, Chang JW. A grid-based k-nearest neighbor join for large scale datasets on MapReduce Proceedings - 2015 Ieee 17th International Conference On High Performance Computing and Communications, 2015 Ieee 7th International Symposium On Cyberspace Safety and Security and 2015 Ieee 12th International Conference On Embedded Software and Systems, Hpcc-Css-Icess 2015. 888-891. DOI: 10.1109/HPCC-CSS-ICESS.2015.189  0.4
2014 Sim HT, Kim SR, Beom MS, Chang JW, Kim NR, Jang MH, Ryu SW. Neurologic outcomes of preoperative acute silent cerebral infarction in patients with cardiac surgery. The Korean Journal of Thoracic and Cardiovascular Surgery. 47: 510-6. PMID 25551071 DOI: 10.5090/kjtcs.2014.47.6.510  0.4
2014 Galmozzi A, Sonne SB, Altshuler-Keylin S, Hasegawa Y, Shinoda K, Luijten IH, Chang JW, Sharp LZ, Cravatt BF, Saez E, Kajimura S. ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. Cell Reports. 9: 1584-93. PMID 25466254 DOI: 10.1016/j.celrep.2014.10.066  0.8
2014 Manna JD, Wepy JA, Hsu KL, Chang JW, Cravatt BF, Marnett LJ. Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. The Journal of Biological Chemistry. 289: 33741-53. PMID 25301951 DOI: 10.1074/jbc.M114.582353  0.8
2014 Ding YD, Chang JW, Guo J, Chen D, Li S, Xu Q, Deng XX, Cheng YJ, Chen LL. Prediction and functional analysis of the sweet orange protein-protein interaction network. Bmc Plant Biology. 14: 213. PMID 25091279 DOI: 10.1186/s12870-014-0213-7  0.4
2014 Wu TH, Li YY, Wu TL, Chang JW, Chou WC, Hsieh LL, Chen JR, Yeh KY. Culture supernatants of different colon cancer cell lines induce specific phenotype switching and functional alteration of THP-1 cells. Cellular Immunology. 290: 107-15. PMID 24960291 DOI: 10.1016/j.cellimm.2014.05.015  0.4
2014 Dominguez E, Galmozzi A, Chang JW, Hsu KL, Pawlak J, Li W, Godio C, Thomas J, Partida D, Niessen S, O'Brien PE, Russell AP, Watt MJ, Nomura DK, Cravatt BF, et al. Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nature Chemical Biology. 10: 113-21. PMID 24362705 DOI: 10.1038/nchembio.1429  0.8
2013 Hsu KL, Tsuboi K, Chang JW, Whitby LR, Speers AE, Pugh H, Cravatt BF. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). Journal of Medicinal Chemistry. 56: 8270-9. PMID 24152295 DOI: 10.1021/jm400899c  0.8
2013 Holly SP, Chang JW, Li W, Niessen S, Phillips RM, Piatt R, Black JL, Smith MC, Boulaftali Y, Weyrich AS, Bergmeier W, Cravatt BF, Parise LV. Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation. Chemistry & Biology. 20: 1125-34. PMID 23993462 DOI: 10.1016/j.chembiol.2013.07.011  0.8
2013 Niphakis MJ, Cognetta AB, Chang JW, Buczynski MW, Parsons LH, Byrne F, Burston JJ, Chapman V, Cravatt BF. Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors. Acs Chemical Neuroscience. 4: 1322-32. PMID 23731016 DOI: 10.1021/cn400116z  0.8
2013 Chang JW, Cognetta AB, Niphakis MJ, Cravatt BF. Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition. Acs Chemical Biology. 8: 1590-9. PMID 23701408 DOI: 10.1021/cb400261h  0.8
2013 Bisogno T, Mahadevan A, Coccurello R, Chang JW, Allarà M, Chen Y, Giacovazzo G, Lichtman A, Cravatt B, Moles A, Di Marzo V. A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects British Journal of Pharmacology. 169: 784-793. PMID 23072382 DOI: 10.1111/bph.12013  0.8
2012 Adibekian A, Martin BR, Chang JW, Hsu KL, Tsuboi K, Bachovchin DA, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder PS, Rosen H, Cravatt BF. Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes. Journal of the American Chemical Society. 134: 10345-8. PMID 22690931 DOI: 10.1021/ja303400u  0.8
2012 Chang JW, Niphakis MJ, Lum KM, Cognetta AB, Wang C, Matthews ML, Niessen S, Buczynski MW, Parsons LH, Cravatt BF. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chemistry & Biology. 19: 579-88. PMID 22542104 DOI: 10.1016/j.chembiol.2012.03.009  0.8
2012 Chang JW, Moellering RE, Cravatt BF. An activity-based imaging probe for the integral membrane hydrolase KIAA1363. Angewandte Chemie (International Ed. in English). 51: 966-70. PMID 22162147 DOI: 10.1002/anie.201107236  0.8
2011 Nomura DK, Lombardi DP, Chang JW, Niessen S, Ward AM, Long JZ, Hoover HH, Cravatt BF. Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer. Chemistry & Biology. 18: 846-56. PMID 21802006 DOI: 10.1016/j.chembiol.2011.05.009  0.8
2011 Chang JW, Nomura DK, Cravatt BF. A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis. Chemistry & Biology. 18: 476-84. PMID 21513884 DOI: 10.1016/j.chembiol.2011.02.008  0.8
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