Kevin Foust - Publications

Neuroscience Ohio State University, Columbus, Columbus, OH 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Mendell JR, Al-Zaidy S, Shell R, Arnold WD, Rodino-Klapac LR, Prior TW, Lowes L, Alfano L, Berry K, Church K, Kissel JT, Nagendran S, L'Italien J, Sproule DM, Wells C, ... ... Foust KD, et al. Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy. The New England Journal of Medicine. 377: 1713-1722. PMID 29091557 DOI: 10.1056/Nejmoa1706198  0.76
2017 Gombash SE, Cowley CJ, Fitzgerald JA, Lepak CA, Neides MG, Hook K, Todd LJ, Wang GD, Mueller C, Kaspar BK, Bielefeld EC, Fischer AJ, Wood JD, Foust KD. Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques. Gene Therapy. PMID 28771235 DOI: 10.1038/Gt.2017.72  0.76
2016 Song S, Miranda CJ, Braun L, Meyer K, Frakes AE, Ferraiuolo L, Likhite S, Bevan AK, Foust KD, McConnell MJ, Walker CM, Kaspar BK. Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis. Nature Medicine. PMID 26928464 DOI: 10.1038/Nm.4052  0.76
2016 Gombash SE, Foust KD. Systemic Gene Therapy for Targeting the CNS. Methods in Molecular Biology (Clifton, N.J.). 1382: 231-7. PMID 26611590 DOI: 10.1007/978-1-4939-3271-9_16  0.76
2015 Nizzardo M, Simone C, Rizzo F, Salani S, Dametti S, Rinchetti P, Del Bo R, Foust K, Kaspar BK, Bresolin N, Comi GP, Corti S. Gene therapy rescues disease phenotype in a spinal muscular atrophy with respiratory distress type 1 (SMARD1) mouse model. Science Advances. 1: e1500078. PMID 26601156 DOI: 10.1126/Sciadv.1500078  0.76
2015 Iyer CC, McGovern VL, Murray JD, Gombash SE, Zaworski PG, Foust KD, Janssen PM, Burghes AH. Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA. Human Molecular Genetics. PMID 26276812 DOI: 10.1093/Hmg/Ddv332  0.76
2015 Gombash SE, Cowley CJ, Fitzgerald JA, Iyer CC, Fried D, McGovern VL, Williams KC, Burghes AH, Christofi FL, Gulbransen BD, Foust KD. SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice. Human Molecular Genetics. PMID 26223459 DOI: 10.1093/Hmg/Ddv292  0.76
2015 McGovern VL, Iyer CC, Arnold WD, Gombash SE, Zaworski PG, Blatnik AJ, Foust KD, Burghes AH. SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA. Human Molecular Genetics. 24: 5524-41. PMID 26206889 DOI: 10.1093/Hmg/Ddv283  0.76
2015 Xie Y, Zhou B, Lin MY, Wang S, Foust KD, Sheng ZH. Endolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice. Neuron. 87: 355-70. PMID 26182418 DOI: 10.1016/j.neuron.2015.06.026  0.76
2015 Gombash SE, Cowley CJ, Fitzgerald JA, Iyer CC, Fried D, McGovern VL, Williams KC, Burghes AH, Christofi FL, Gulbransen BD, Foust KD. SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice. Human Molecular Genetics. 24: 3847-60. PMID 25859009 DOI: 10.1093/Hmg/Ddv127  0.76
2015 Weber-Adrian D, Thévenot E, O'Reilly MA, Oakden W, Akens MK, Ellens N, Markham-Coultes K, Burgess A, Finkelstein J, Yee AJ, Whyne CM, Foust KD, Kaspar BK, Stanisz GJ, Chopra R, et al. Gene delivery to the spinal cord using MRI-guided focused ultrasound. Gene Therapy. 22: 568-77. PMID 25781651 DOI: 10.1038/Gt.2015.25  0.76
2015 Meyer K, Ferraiuolo L, Schmelzer L, Braun L, McGovern V, Likhite S, Michels O, Govoni A, Fitzgerald J, Morales P, Foust KD, Mendell JR, Burghes AH, Kaspar BK. Improving single injection CSF delivery of AAV9-mediated gene therapy for SMA: a dose-response study in mice and nonhuman primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 477-87. PMID 25358252 DOI: 10.1038/Mt.2014.210  0.76
2014 Gombash Lampe SE, Kaspar BK, Foust KD. Intravenous injections in neonatal mice. Journal of Visualized Experiments : Jove. e52037. PMID 25407048 DOI: 10.3791/52037  0.76
2014 Gombash SE, Cowley CJ, Fitzgerald JA, Hall JC, Mueller C, Christofi FL, Foust KD. Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice. Frontiers in Molecular Neuroscience. 7: 81. PMID 25360081 DOI: 10.3389/fnmol.2014.00081  0.76
2014 Frakes AE, Ferraiuolo L, Haidet-Phillips AM, Schmelzer L, Braun L, Miranda CJ, Ladner KJ, Bevan AK, Foust KD, Godbout JP, Popovich PG, Guttridge DC, Kaspar BK. Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis. Neuron. 81: 1009-23. PMID 24607225 DOI: 10.1016/J.Neuron.2014.01.013  0.76
2013 Foust KD, Salazar DL, Likhite S, Ferraiuolo L, Ditsworth D, Ilieva H, Meyer K, Schmelzer L, Braun L, Cleveland DW, Kaspar BK. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2148-59. PMID 24008656 DOI: 10.1038/Mt.2013.211  0.76
2013 Garg SK, Lioy DT, Cheval H, McGann JC, Bissonnette JM, Murtha MJ, Foust KD, Kaspar BK, Bird A, Mandel G. Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13612-20. PMID 23966684 DOI: 10.1523/Jneurosci.1854-13.2013  0.76
2012 Thévenot E, Jordão JF, O'Reilly MA, Markham K, Weng YQ, Foust KD, Kaspar BK, Hynynen K, Aubert I. Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound. Human Gene Therapy. 23: 1144-55. PMID 22838844 DOI: 10.1089/Hum.2012.013  0.76
2012 Samaranch L, Salegio EA, San Sebastian W, Kells AP, Foust KD, Bringas JR, Lamarre C, Forsayeth J, Kaspar BK, Bankiewicz KS. Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates. Human Gene Therapy. 23: 382-9. PMID 22201473 DOI: 10.1089/Hum.2011.200  0.76
2012 Porensky PN, Mitrpant C, McGovern VL, Bevan AK, Foust KD, Kaspar BK, Wilton SD, Burghes AH. A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in mouse. Human Molecular Genetics. 21: 1625-38. PMID 22186025 DOI: 10.1093/Hmg/Ddr600  0.76
2011 Lin Y, Roman K, Foust KD, Kaspar BK, Bailey MT, Stephens RL. Glutamate Transporter GLT-1 Upregulation Attenuates Visceral Nociception and Hyperalgesia via Spinal Mechanisms Not Related to Anti-Inflammatory or Probiotic Effects. Pain Research and Treatment. 2011: 507029. PMID 22220274 DOI: 10.1155/2011/507029  0.76
2011 Bockstael O, Foust KD, Kaspar B, Tenenbaum L. Recombinant AAV delivery to the central nervous system. Methods in Molecular Biology (Clifton, N.J.). 807: 159-77. PMID 22034030 DOI: 10.1007/978-1-61779-370-7_7  0.76
2011 Haidet-Phillips AM, Hester ME, Miranda CJ, Meyer K, Braun L, Frakes A, Song S, Likhite S, Murtha MJ, Foust KD, Rao M, Eagle A, Kammesheidt A, Christensen A, Mendell JR, et al. Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nature Biotechnology. 29: 824-8. PMID 21832997 DOI: 10.1038/Nbt.1957  0.76
2011 Bevan AK, Duque S, Foust KD, Morales PR, Braun L, Schmelzer L, Chan CM, McCrate M, Chicoine LG, Coley BD, Porensky PN, Kolb SJ, Mendell JR, Burghes AH, Kaspar BK. Systemic gene delivery in large species for targeting spinal cord, brain, and peripheral tissues for pediatric disorders. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1971-80. PMID 21811247 DOI: 10.1038/Mt.2011.157  0.76
2011 Lioy DT, Garg SK, Monaghan CE, Raber J, Foust KD, Kaspar BK, Hirrlinger PG, Kirchhoff F, Bissonnette JM, Ballas N, Mandel G. A role for glia in the progression of Rett's syndrome. Nature. 475: 497-500. PMID 21716289 DOI: 10.1038/Nature10214  0.76
2011 Foust KD, Kaspar BK. Delivery strategies for RNAi to the nervous system Neuromethods. 58: 59-76. DOI: 10.1007/978-1-61779-114-7_4  0.76
2010 Bevan AK, Hutchinson KR, Foust KD, Braun L, McGovern VL, Schmelzer L, Ward JG, Petruska JC, Lucchesi PA, Burghes AH, Kaspar BK. Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery. Human Molecular Genetics. 19: 3895-905. PMID 20639395 DOI: 10.1093/Hmg/Ddq300  0.76
2010 Foust KD, Wang X, McGovern VL, Braun L, Bevan AK, Haidet AM, Le TT, Morales PR, Rich MM, Burghes AH, Kaspar BK. Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN. Nature Biotechnology. 28: 271-4. PMID 20190738 DOI: 10.1038/Nbt.1610  0.76
2009 Foust KD, Kaspar BK. Over the barrier and through the blood: to CNS delivery we go. Cell Cycle (Georgetown, Tex.). 8: 4017-8. PMID 19949299 DOI: 10.4161/Cc.8.24.10245  0.76
2009 Hester ME, Foust KD, Kaspar RW, Kaspar BK. AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS. Current Gene Therapy. 9: 428-33. PMID 19860657 DOI: 10.2174/156652309789753383  0.76
2009 Manfredsson FP, Tumer N, Erdos B, Landa T, Broxson CS, Sullivan LF, Rising AC, Foust KD, Zhang Y, Muzyczka N, Gorbatyuk OS, Scarpace PJ, Mandel RJ. Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 980-91. PMID 19277011 DOI: 10.1038/Mt.2009.45  0.76
2009 Foust KD, Nurre E, Montgomery CL, Hernandez A, Chan CM, Kaspar BK. Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes. Nature Biotechnology. 27: 59-65. PMID 19098898 DOI: 10.1038/Nbt.1515  0.76
2009 Liqun Wang R, McLaughlin T, Cossette T, Tang Q, Foust K, Campbell-Thompson M, Martino A, Cruz P, Loiler S, Mueller C, Flotte TR. Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 81-7. PMID 18941444 DOI: 10.1038/Mt.2008.217  0.76
2008 Foust KD, Flotte TR, Reier PJ, Mandel RJ. Recombinant adeno-associated virus-mediated global anterograde delivery of glial cell line-derived neurotrophic factor to the spinal cord: comparison of rubrospinal and corticospinal tracts in the rat. Human Gene Therapy. 19: 71-82. PMID 18072858 DOI: 10.1089/Hum.2007.104  0.76
2008 Foust KD, Poirier A, Pacak CA, Mandel RJ, Flotte TR. Neonatal intraperitoneal or intravenous injections of recombinant adeno-associated virus type 8 transduce dorsal root ganglia and lower motor neurons. Human Gene Therapy. 19: 61-70. PMID 18052722 DOI: 10.1089/Hum.2007.093  0.76
2006 Mandel RJ, Manfredsson FP, Foust KD, Rising A, Reimsnider S, Nash K, Burger C. Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 463-83. PMID 16412695 DOI: 10.1016/J.Ymthe.2005.11.009  0.76
2005 Virella-Lowell I, Zusman B, Foust K, Loiler S, Conlon T, Song S, Chesnut KA, Ferkol T, Flotte TR. Enhancing rAAV vector expression in the lung. The Journal of Gene Medicine. 7: 842-50. PMID 15838934 DOI: 10.1002/Jgm.759  0.76
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