Kwok K. Lai, Ph.D. - Related publications

Affiliations: 
2013 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Traditional Chinese Medicine, Cancer
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Li M, Wang T, Tian H, Wei G, Zhao L, Shi Y. Macrophage-derived exosomes accelerate wound healing through their anti-inflammation effects in a diabetic rat model. Artificial Cells, Nanomedicine, and Biotechnology. 47: 3793-3803. PMID 31556314 DOI: 10.1080/21691401.2019.1669617   
2019 Wang F, Xi Y, Liu W, Li J, Zhang Y, Jia M, He Q, Zhao H, Wang S. Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3/Nrf2 Pathway. Journal of Diabetes Research. 2019: 5734723. PMID 31612149 DOI: 10.1155/2019/5734723   
2019 Zhu X, Guo F, Tang H, Huang C, Xie G, Huang T, Li Y, Liu C, Wang H, Chen B. Islet Transplantation Attenuating Testicular Injury in Type 1 Diabetic Rats Is Associated with Suppression of Oxidative Stress and Inflammation via Nrf-2/HO-1 and NF-B Pathways. Journal of Diabetes Research. 2019: 8712492. PMID 31583254 DOI: 10.1155/2019/8712492   
2019 Davoodi M, Karimooy FN, Budde T, Ortega-Martinez S, Moradi-Kor N. Beneficial effects of Japanese sake yeast supplement on biochemical, antioxidant, and anti-inflammatory factors in streptozotocin-induced diabetic rats. Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy. 12: 1667-1673. PMID 31564934 DOI: 10.2147/DMSO.S220181   
2019 Srivastava S, Pandey H, Singh SK, Tripathi YB. Anti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets. Bioscience Trends. PMID 31597821 DOI: 10.5582/bst.2019.01181   
2019 Elrashidy RA, Liu G. Long-term diabetes causes molecular alterations related to fibrosis and apoptosis in rat urinary bladder. Experimental and Molecular Pathology. 104304. PMID 31479659 DOI: 10.1016/j.yexmp.2019.104304   
2019 Li M, Yu H, Pan H, Zhou X, Ruan Q, Kong D, Chu Z, Li H, Huang J, Huang X, Chau A, Xie W, Ding Y, Yao P. Nrf2 Suppression Delays Diabetic Wound Healing Through Sustained Oxidative Stress and Inflammation. Frontiers in Pharmacology. 10: 1099. PMID 31616304 DOI: 10.3389/fphar.2019.01099   
2019 Gong DJ, Wang L, Yang YY, Zhang JJ, Liu XH. Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis. Renal Failure. 41: 750-761. PMID 31441362 DOI: 10.1080/0886022X.2019.1643737   
2019 He Y, Shi B, Zhao X, Sui J. Sphingosine-1-phosphate induces islet β-cell proliferation and decreases cell apoptosis in high-fat diet/streptozotocin diabetic mice. Experimental and Therapeutic Medicine. 18: 3415-3424. PMID 31602216 DOI: 10.3892/etm.2019.7999   
2019 Ahmed OM, Ali TM, Abdel Gaid MA, Elberry AA. Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats. Plos One. 14: e0214349. PMID 31527864 DOI: 10.1371/journal.pone.0214349   
2019 Nna VU, Abu Bakar AB, Ahmad A, Eleazu CO, Mohamed M. Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin-Induced Diabetic Rats: Combined Protective Effects of Malaysian Propolis and Metformin. Antioxidants (Basel, Switzerland). 8. PMID 31600920 DOI: 10.3390/antiox8100465   
2019 Yang X, Cao J, Du Y, Gong Q, Cheng Y, Su G. Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 25: 6742-6754. PMID 31494661 DOI: 10.12659/MSM.915748   
2019 Gao J, Cheng Y, Hao H, Yin Y, Xue J, Zhang Q, Li L, Liu J, Xie Z, Yu S, Li B, Han W, Mu Y. Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic mice. Stem Cell Research & Therapy. 10: 259. PMID 31426846 DOI: 10.1186/s13287-019-1338-2   
2019 Liao Z, Zhang J, Wang J, Yan T, Xu F, Wu B, Xiao F, Bi K, Niu J, Jia Y. The anti-nephritic activity of a polysaccharide from okra (Abelmoschus esculentus (L.) Moench) via modulation of AMPK-Sirt1-PGC-1α signaling axis mediated anti-oxidative in type 2 diabetes model mice. International Journal of Biological Macromolecules. PMID 31442509 DOI: 10.1016/j.ijbiomac.2019.08.149   
2019 Chen YJ, Wu SC, Wang HC, Wu TH, Yuan SF, Lu TT, Liaw WF, Wang YM. Activation of Angiogenesis and Wound Healing in Diabetic Mice Using NO-Delivery Dinitrosyl Iron Complexes. Molecular Pharmaceutics. PMID 31436106 DOI: 10.1021/acs.molpharmaceut.9b00586   
2019 Hsiao CC, Lin CC, Hou YS, Ko JY, Wang CJ. Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model. International Journal of Molecular Sciences. 20. PMID 31590394 DOI: 10.3390/ijms20194934   
2019 Lin CH, Hsiao LW, Kuo YH, Shih CC. Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from , in Streptozotocin-Induced Diabetic Mice. International Journal of Molecular Sciences. 20. PMID 31581697 DOI: 10.3390/ijms20194897   
2019 Zhao J, Liu L, Zhang L, Lv J, Guo X, Li X, Zhao T. Sodium ferulate attenuates high-glucose-induced oxidative injury in HT22 hippocampal cells. Experimental and Therapeutic Medicine. 18: 2015-2020. PMID 31452700 DOI: 10.3892/etm.2019.7822   
2019 Wang R, Yan Y, Li C. LINC00462 is involved in high glucose-induced apoptosis of renel tubular epithelial cells via AKT pathway. Cell Biology International. PMID 31489995 DOI: 10.1002/cbin.11231   
2019 Wu B, Huang XY, Li L, Fan XH, Li PC, Huang CQ, Xiao J, Gui R, Wang S. Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model. Journal of Cellular and Molecular Medicine. PMID 31565849 DOI: 10.1111/jcmm.14638   
2019 Kolling J, Kolling J, Franceschi ID, Nishihira VSK, Baldissera MD, Pinto CG, Mezzomo NJ, Carmo GMD, Feksa LR, Fernandes LS, Orengo G, Vaucher RA, Giongo JL, Wyse ATS, Wannmacher CMD, et al. Resveratrol and resveratrol-hydroxypropyl-β-cyclodextrin complex recovered the changes of creatine kinase and Na+, K+-ATPase activities found in the spleen from streptozotocin-induced diabetic rats. Anais Da Academia Brasileira De Ciencias. 91: e20181330. PMID 31508665 DOI: 10.1590/0001-3765201920181330   
2019 Liu ZZ, Weng HB, Zhang LJ, Pan LY, Sun W, Chen HX, Chen MY, Zeng T, Zhang YY, Chen DF, Li H. Bupleurum polysaccharides ameliorated renal injury in diabetic mice associated with suppression of HMGB1-TLR4 signaling. Chinese Journal of Natural Medicines. 17: 641-649. PMID 31526499 DOI: 10.1016/S1875-5364(19)30078-0   
2019 Pitasi CL, Liu J, Gausserès B, Pommier G, Delangre E, Armanet M, Cattan P, Mégarbane B, Hanak AS, Maouche K, Bailbé D, Portha B, Movassat J. Implication of glycogen synthase kinase 3 in diabetes-associated islet inflammation. The Journal of Endocrinology. PMID 31600727 DOI: 10.1530/JOE-19-0239   
2019 Inam-U-Llah, Shi X, Zhang M, Li K, Wu P, Suleman R, Shahbaz M, Taj A, Piao F. Protective Effect of Taurine on Apoptosis of Spinal Cord Cells in Diabetic Neuropathy Rats. Advances in Experimental Medicine and Biology. 1155: 875-887. PMID 31468454 DOI: 10.1007/978-981-13-8023-5_74   
2019 Sierra-Mondragon E, Rodríguez-Muñoz R, Namorado-Tonix C, Molina-Jijon E, Romero-Trejo D, Pedraza-Chaverri J, Reyes JL. All-Trans Retinoic Acid Attenuates Fibrotic Processes by Downregulating TGF-β1/Smad3 in Early Diabetic Nephropathy. Biomolecules. 9. PMID 31557800 DOI: 10.3390/biom9100525   
2019 Ang WJ, Zunaina E, Norfadzillah AJ, Raja-Norliza RO, Julieana M, Ab-Hamid SA, Mahaneem M. Evaluation of vascular endothelial growth factor levels in tears and serum among diabetic patients. Plos One. 14: e0221481. PMID 31437234 DOI: 10.1371/journal.pone.0221481   
2019 Zhang Y, Huo W, Wen Y, Li H. Silencing Nogo-B receptor inhibits penile corpus cavernosum vascular smooth muscle cell apoptosis of rats with diabetic erectile dysfunction by down-regulating ICAM-1. Plos One. 14: e0220715. PMID 31442237 DOI: 10.1371/journal.pone.0220715   
2019 Zhang L, Yu J, Ye M, Zhao H. Upregulation of - inhibits high-glucose induced inflammation and oxidative stress in HRECs and attenuates diabetic retinopathy by modulating / signaling pathway: an in vitro study. Cell & Bioscience. 9: 67. PMID 31462987 DOI: 10.1186/s13578-019-0331-x   
2019 Wang Y, Lu YH, Tang C, Xue M, Li XY, Chang YP, Cheng Y, Li T, Yu XC, Sun B, Li CJ, Chen LM. Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway. Frontiers in Pharmacology. 10: 886. PMID 31447680 DOI: 10.3389/fphar.2019.00886   
2019 Kaya D, Kaji K, Tsuji Y, Yamashita S, Kitagawa K, Ozutsumi T, Fujinaga Y, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T, Yoshiji H. TGR5 Activation Modulates an Inhibitory Effect on Liver Fibrosis Development Mediated by Anagliptin in Diabetic Rats. Cells. 8. PMID 31561561 DOI: 10.3390/cells8101153   
2019 Ying L, Li N, He Z, Zeng X, Nan Y, Chen J, Miao P, Ying Y, Lin W, Zhao X, Lu L, Chen M, Cen W, Guo T, Li X, et al. Fibroblast growth factor 21 Ameliorates diabetes-induced endothelial dysfunction in mouse aorta via activation of the CaMKK2/AMPKα signaling pathway. Cell Death & Disease. 10: 665. PMID 31511499 DOI: 10.1038/s41419-019-1893-6   
2019 Qu X, Chen X, Shi Q, Wang X, Wang D, Yang L. Resveratrol alleviates ischemia/reperfusion injury of diabetic myocardium via inducing autophagy. Experimental and Therapeutic Medicine. 18: 2719-2725. PMID 31555372 DOI: 10.3892/etm.2019.7846   
2019 Malekshahi H, Bahrami G, Miraghaee S, Ahmadi SA, Sajadimajd S, Hatami R, Mohammadi B, Keshavarzi S. Momordica charantia reverses type II diabetes in rat. Journal of Food Biochemistry. e13021. PMID 31441956 DOI: 10.1111/jfbc.13021   
2019 Djelić N, Radaković M, Borozan S, Dimirijević-Srećković V, Pajović N, Vejnović B, Borozan N, Bankoglu EE, Stopper H, Stanimirović Z. Oxidative stress and DNA damage in peripheral blood mononuclear cells from normal, obese, prediabetic and diabetic persons exposed to adrenaline in vitro. Mutation Research. 843: 81-89. PMID 31421743 DOI: 10.1016/j.mrgentox.2019.01.013   
2019 Huo YN, Yeh SD, Lee WS. Androgen receptor activation reduces the endothelial cell proliferation through activating the cSrc/AKT/p38/ERK/NFκB-mediated pathway. The Journal of Steroid Biochemistry and Molecular Biology. 105459. PMID 31470108 DOI: 10.1016/j.jsbmb.2019.105459   
2019 Xiao Q, Zhao XY, Jiang RC, Chen XH, Zhu X, Chen KF, Chen SY, Zhang XL, Qin Y, Liu YH, Luo JD. Increased expression of Sonic hedgehog restores diabetic endothelial progenitor cells and improves cardiac repair after acute myocardial infarction in diabetic mice. International Journal of Molecular Medicine. PMID 31524224 DOI: 10.3892/ijmm.2019.4277   
2019 Zhang Z, Lin J, Nisar M, Chen T, Xu T, Zheng G, Wang C, Jin H, Chen J, Gao W, Tian N, Wang X, Zhang X. The Sirt1/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics. Oxidative Medicine and Cellular Longevity. 2019: 7959573. PMID 31583043 DOI: 10.1155/2019/7959573   
2019 Bai Y, Zhu R, Tian Y, Li R, Chen B, Zhang H, Xia B, Zhao D, Mo F, Zhang D, Gao S. Catalpol in Diabetes and its Complications: A Review of Pharmacology, Pharmacokinetics, and Safety. Molecules (Basel, Switzerland). 24. PMID 31514313 DOI: 10.3390/molecules24183302   
2019 Li H, Wang Y, Zhou Z, Tian F, Yang H, Yan J. Combination of leflunomide and benazepril reduces renal injury of diabetic nephropathy rats and inhibits high-glucose induced cell apoptosis through regulation of NF-κB, TGF-β and TRPC6. Renal Failure. 41: 899-906. PMID 31552773 DOI: 10.1080/0886022X.2019.1665547   
2019 Ko KI, Syverson AL, Kralik RM, Choi J, DerGarabedian BP, Chen C, Graves DT. Diabetes-Induced NF-κB Dysregulation in Skeletal Stem Cells Prevents Resolution of Inflammation. Diabetes. PMID 31439641 DOI: 10.2337/db19-0496   
2019 Wang X, Huang H, Su C, Zhong Q, Wu G. Cilostazol ameliorates high free fatty acid (FFA)-induced activation of NLRP3 inflammasome in human vascular endothelial cells. Artificial Cells, Nanomedicine, and Biotechnology. 47: 3704-3710. PMID 31514535 DOI: 10.1080/21691401.2019.1665058   
2019 Msomi NZ, Shode FO, Pooe OJ, Mazibuko-Mbeje S, Simelane MBC. Iso-Mukaadial Acetate from Enhances Glucose Uptake in the L6 Rat Myoblast Cell Line. Biomolecules. 9. PMID 31546691 DOI: 10.3390/biom9100520   
2019 Li XX, Ling SK, Hu MY, Ma Y, Li Y, Huang PL. Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats. Free Radical Biology & Medicine. PMID 31541678 DOI: 10.1016/j.freeradbiomed.2019.09.015   
2019 Sheng X, Yao K, Shao A, Tu S, Zhang X, Chen T, Yao D. The Role of Insulin Glargine and Human Insulin in the Regulation of Thyroid Proliferation Through Mitogenic Signaling. Frontiers in Endocrinology. 10: 594. PMID 31555212 DOI: 10.3389/fendo.2019.00594   
2019 Zhang X, Qu P, Zhao H, Zhao T, Cao N. COX‑2 promotes epithelial‑mesenchymal transition and migration in osteosarcoma MG‑63 cells via PI3K/AKT/NF‑κB signaling. Molecular Medicine Reports. PMID 31485669 DOI: 10.3892/mmr.2019.10598   
2019 Wan FC, Zhang C, Jin Q, Wei C, Zhao HB, Zhang XL, You W, Liu XM, Liu GF, Liu YF, Tan XW. Protective Effects of Astaxanthin on Lipopolysaccharide-Induced Inflammation in Bovine Endometrial Epithelial Cells. Biology of Reproduction. PMID 31566218 DOI: 10.1093/biolre/ioz187   
2019 Ajjan RA, Schroeder V. Role of complement in diabetes. Molecular Immunology. 114: 270-277. PMID 31400630 DOI: 10.1016/j.molimm.2019.07.031   
2019 Marafie SK, Al-Shawaf EM, Abubaker J, Arefanian H. Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells. Biological Research. 52: 44. PMID 31426858 DOI: 10.1186/s40659-019-0253-4   
2019 Zhang D, Gava AL, Van Krieken R, Mehta N, Li R, Gao B, Desjardins EM, Steinberg GR, Hawke T, Krepinsky JC. The caveolin-1 regulated protein follistatin protects against diabetic kidney disease. Kidney International. PMID 31492508 DOI: 10.1016/j.kint.2019.05.032   
2019 Vieira R, Souto SB, Sánchez-López E, Machado AL, Severino P, Jose S, Santini A, Silva AM, Fortuna A, García ML, Souto EB. Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Strategies for In Vivo Administration: Part-II. Journal of Clinical Medicine. 8. PMID 31466386 DOI: 10.3390/jcm8091332