Hunter C. Champion, Ph.D. - Publications

Affiliations: 
2000 Tulane University, New Orleans, LA, United States 
Area:
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231 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nossaman BD, Champion HC, Kaye AD, Anwar M, Feng CJ, Kadowitz PJ. Nociceptin Has Vasodilator Activity in the Pulmonary Vascular Bed of the Rat. Journal of Cardiovascular Pharmacology and Therapeutics. 3: 253-258. PMID 10684506 DOI: 10.1177/107424849800300309  0.586
2019 Schiller NK, Champion HC, Hugghins SY, Timothy AM, Murphy WA, Coy DH, Peter JR, Kadowitz PJ, McNamara DB. Adrenomedullin Does Not Inhibit Human Platelet Aggregation. Journal of Cardiovascular Pharmacology and Therapeutics. 3: 223-228. PMID 10684501 DOI: 10.1177/107424849800300304  0.455
2019 Nossaman BD, Kaye AD, Champion HC, Kang B, Feng CJ, Kadowitz PJ. Effects of Phentolamine on Responses to PAMP in the Hindquarters Vascular Bed of the Rat. Journal of Cardiovascular Pharmacology and Therapeutics. 2: 153-157. PMID 10684454 DOI: 10.1177/107424849700200302  0.613
2015 Sopko NA, Matsui H, Hannan JL, Berkowitz D, Champion HC, Hsu LL, Musicki B, Burnett AL, Bivalacqua TJ. Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation. The Journal of Sexual Medicine. 12: 1878-85. PMID 26346631 DOI: 10.1111/Jsm.12976  0.394
2014 Hill MR, Simon MA, Valdez-Jasso D, Zhang W, Champion HC, Sacks MS. Structural and mechanical adaptations of right ventricle free wall myocardium to pressure overload. Annals of Biomedical Engineering. 42: 2451-65. PMID 25164124 DOI: 10.1007/S10439-014-1096-3  0.323
2014 Musicki B, Bivalacqua TJ, Champion HC, Burnett AL. Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis. The Journal of Sexual Medicine. 11: 424-30. PMID 24251665 DOI: 10.1111/Jsm.12391  0.417
2014 Shatat MA, Tian H, Zhang R, Tandon G, Hale A, Fritz JS, Zhou G, Martínez-González J, Rodríguez C, Champion HC, Jain MK, Hamik A. Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension. American Journal of Respiratory Cell and Molecular Biology. 50: 647-53. PMID 24156273 DOI: 10.1165/rcmb.2013-0135OC  0.3
2013 Bivalacqua TJ, Musicki B, Hsu LL, Berkowitz DE, Champion HC, Burnett AL. Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress. Plos One. 8: e68028. PMID 23844149 DOI: 10.1371/Journal.Pone.0068028  0.42
2013 George MP, Champion HC, Simon M, Guyach S, Tarantelli R, Kling HM, Brower A, Janssen C, Murphy J, Carney JP, Morris A, Gladwin MT, Norris KA. Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension. American Journal of Respiratory Cell and Molecular Biology. 48: 374-81. PMID 23239493 DOI: 10.1165/Rcmb.2011-0434Oc  0.318
2013 Batal O, Dardari Z, Lopez-Candales A, Champion H, Mathier M. PROGNOSTIC VALUE OF PERICARDIAL EFFUSION ON SERIAL ECHOCARDIOGRAMS IN PULMONARY ARTERIAL HYPERTENSION Journal of the American College of Cardiology. 61: E1303. DOI: 10.1016/S0735-1097(13)61303-0  0.303
2012 Hemnes AR, Maynard KB, Champion HC, Gleaves L, Penner N, West J, Newman JH. Testosterone negatively regulates right ventricular load stress responses in mice. Pulmonary Circulation. 2: 352-8. PMID 23130103 DOI: 10.4103/2045-8932.101647  0.333
2012 Segal R, Hannan JL, Liu X, Kutlu O, Burnett AL, Champion HC, Kim JH, Steppan J, Berkowitz DE, Bivalacqua TJ. Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats. Journal of Andrology. 33: 1169-75. PMID 22492840 DOI: 10.2164/Jandrol.111.015834  0.521
2012 Saggar R, Lewis GD, Systrom DM, Champion HC, Naeije R, Saggar R. Pulmonary vascular responses to exercise: a haemodynamic observation. The European Respiratory Journal. 39: 231-4. PMID 22298608 DOI: 10.1183/09031936.00166211  0.313
2012 Morris A, Gingo MR, George MP, Lucht L, Kessinger C, Singh V, Hillenbrand M, Busch M, McMahon D, Norris KA, Champion HC, Gladwin MT, Zhang Y, Steele C, Sciurba FC. Cardiopulmonary function in individuals with HIV infection in the antiretroviral therapy era. Aids (London, England). 26: 731-40. PMID 22210636 DOI: 10.1097/Qad.0B013E32835099Ae  0.302
2012 Nwasike CO, Baust JJ, Bauer E, Bauer PM, Bivalacqua TJ, Champion H. ANDROGEN SUPPLEMENTATION IMPROVES RIGHT VENTRICULAR SYSTOLIC FUNCTION IN A CHRONIC HYPOXIA MODEL Journal of the American College of Cardiology. 59: E1609. DOI: 10.1016/S0735-1097(12)61610-6  0.43
2011 Zaiman AL, Damico R, Thoms-Chesley A, Files DC, Kesari P, Johnston L, Swaim M, Mozammel S, Myers AC, Halushka M, El-Haddad H, Shimoda LA, Peng CF, Hassoun PM, Champion HC, et al. A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension. Circulation. 124: 2533-42. PMID 22082675 DOI: 10.1161/Circulationaha.111.034512  0.352
2011 Gebska MA, Stevenson BK, Hemnes AR, Bivalacqua TJ, Haile A, Hesketh GG, Murray CI, Zaiman AL, Halushka MK, Krongkaew N, Strong TD, Cooke CA, El-Haddad H, Tuder RM, Berkowitz DE, ... Champion HC, et al. Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity. Cardiovascular Research. 90: 353-63. PMID 21421555 DOI: 10.1093/Cvr/Cvq410  0.53
2011 Musicki B, Champion HC, Hsu LL, Bivalacqua TJ, Burnett AL. Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis. The Journal of Sexual Medicine. 8: 419-26. PMID 21143412 DOI: 10.1111/J.1743-6109.2010.02123.X  0.419
2011 Bivalacqua T, Musicki B, Kutlu O, Champion H, Burnett A. 915 NADPH-OXIDASE MEDIATED INACTIVATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE CONTRIBUTES TO PRIAPISM IN TRANSGENIC SICKLE CELL MICE Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.806  0.489
2010 Gratzke C, Strong TD, Gebska MA, Champion HC, Stief CG, Burnett AL, Bivalacqua TJ. Activated RhoA/Rho kinase impairs erectile function after cavernous nerve injury in rats. The Journal of Urology. 184: 2197-204. PMID 20851436 DOI: 10.1016/J.Juro.2010.06.094  0.399
2010 LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST. β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4. Journal of Cardiovascular Pharmacology. 56: 548-59. PMID 20729750 DOI: 10.1097/Fjc.0B013E3181F713Fe  0.308
2010 Bivalacqua TJ, Ross AE, Strong TD, Gebska MA, Musicki B, Champion HC, Burnett AL. Attenuated RhoA/Rho-kinase signaling in penis of transgenic sickle cell mice. Urology. 76: 510.e7-12. PMID 20538321 DOI: 10.1016/J.Urology.2010.02.050  0.371
2010 White AR, Ryoo S, Bugaj L, Attarzadeh DO, Thiyagarajan S, Chen K, Attwater S, Abbot B, Li D, Champion HC, Shoukas AA, Nyhan D, Hare JM, Berkowitz DE, Tuday EC. Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway. European Journal of Applied Physiology. 110: 395-404. PMID 20512503 DOI: 10.1007/s00421-010-1514-7  0.305
2010 Campo A, Mathai SC, Le Pavec J, Zaiman AL, Hummers LK, Boyce D, Housten T, Champion HC, Lechtzin N, Wigley FM, Girgis RE, Hassoun PM. Hemodynamic predictors of survival in scleroderma-related pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 182: 252-60. PMID 20339143 DOI: 10.1164/Rccm.200912-1820Oc  0.32
2010 Deng W, Bivalacqua TJ, Champion HC, Hellstrom WJ, Murthy SN, Kadowitz PJ. Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the lung for pulmonary hypertension. Methods in Molecular Biology (Clifton, N.J.). 610: 309-21. PMID 20013186 DOI: 10.1007/978-1-60327-029-8_18  0.68
2010 Deng W, Bivalacqua TJ, Champion HC, Hellstrom WJ, Murthy SN, Kadowitz PJ. Superoxide dismutase - a target for gene therapeutic approach to reduce oxidative stress in erectile dysfunction. Methods in Molecular Biology (Clifton, N.J.). 610: 213-27. PMID 20013181 DOI: 10.1007/978-1-60327-029-8_13  0.631
2010 White TA, Witt TA, Pan S, Mueske CS, Kleppe LS, Holroyd EW, Champion HC, Simari RD. Tissue factor pathway inhibitor overexpression inhibits hypoxia-induced pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 43: 35-45. PMID 19648471 DOI: 10.1165/Rcmb.2009-0144Oc  0.367
2010 Mathai SC, Bueso M, Hummers LK, Boyce D, Lechtzin N, Le Pavec J, Campo A, Champion HC, Housten T, Forfia PR, Zaiman AL, Wigley FM, Girgis RE, Hassoun PM. Disproportionate elevation of N-terminal pro-brain natriuretic peptide in scleroderma-related pulmonary hypertension. The European Respiratory Journal. 35: 95-104. PMID 19643943 DOI: 10.1183/09031936.00074309  0.312
2010 Gratzke C, Strong T, Gebska M, Champion H, Stief C, Burnett A, Bivalacqua T. 80 ACTIVATED RHOA/RHO-KINASE LEADS TO IMPAIRED ERECTILE FUNCTION IN A CAVERNOUS NERVE INJURY RAT MODEL European Urology Supplements. 9: 58. DOI: 10.1016/S1569-9056(10)60086-3  0.373
2009 Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK, Champion HC, Bedja D, Gabrielson KL, Chen J, Xia Y, Hale AB, Channon KM, Halushka MK, Barker N, et al. Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor. Journal of Molecular and Cellular Cardiology. 47: 576-85. PMID 19766235 DOI: 10.1016/J.Yjmcc.2009.06.005  0.302
2009 Kim JH, Bugaj LJ, Oh YJ, Bivalacqua TJ, Ryoo S, Soucy KG, Santhanam L, Webb A, Camara A, Sikka G, Nyhan D, Shoukas AA, Ilies M, Christianson DW, Champion HC, et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 107: 1249-57. PMID 19661445 DOI: 10.1152/Japplphysiol.91393.2008  0.549
2009 Hemnes AR, Forfia PR, Champion HC. Assessment of pulmonary vasculature and right heart by invasive haemodynamics and echocardiography. International Journal of Clinical Practice. Supplement. 4-19. PMID 19624796 DOI: 10.1111/J.1742-1241.2009.02110.X  0.321
2009 Badesch DB, Champion HC, Sanchez MA, Hoeper MM, Loyd JE, Manes A, McGoon M, Naeije R, Olschewski H, Oudiz RJ, Torbicki A. Diagnosis and assessment of pulmonary arterial hypertension. Journal of the American College of Cardiology. 54: S55-66. PMID 19555859 DOI: 10.1016/J.Jacc.2009.04.011  0.326
2009 Ghofrani HA, Barst RJ, Benza RL, Champion HC, Fagan KA, Grimminger F, Humbert M, Simonneau G, Stewart DJ, Ventura C, Rubin LJ. Future perspectives for the treatment of pulmonary arterial hypertension. Journal of the American College of Cardiology. 54: S108-17. PMID 19555854 DOI: 10.1016/J.Jacc.2009.04.014  0.315
2009 Bivalacqua TJ, Musicki B, Hsu LL, Gladwin MT, Burnett AL, Champion HC. Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism. The Journal of Sexual Medicine. 6: 2494-504. PMID 19523035 DOI: 10.1111/J.1743-6109.2009.01359.X  0.472
2009 Thompson-Torgerson CS, Champion HC, Santhanam L, Harris ZL, Shoukas AA. Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1926-32. PMID 19411286 DOI: 10.1152/Ajpheart.00184.2009  0.378
2009 Musicki B, Ross AE, Champion HC, Burnett AL, Bivalacqua TJ. Posttranslational modification of constitutive nitric oxide synthase in the penis. Journal of Andrology. 30: 352-62. PMID 19342700 DOI: 10.2164/Jandrol.108.006999  0.513
2009 Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA. Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 41: 553-61. PMID 19251945 DOI: 10.1165/Rcmb.2008-0271Oc  0.371
2009 Mathai SC, Hummers LK, Champion HC, Wigley FM, Zaiman A, Hassoun PM, Girgis RE. Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease. Arthritis and Rheumatism. 60: 569-77. PMID 19180517 DOI: 10.1002/Art.24267  0.302
2009 Fisher MR, Forfia PR, Chamera E, Housten-Harris T, Champion HC, Girgis RE, Corretti MC, Hassoun PM. Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 179: 615-21. PMID 19164700 DOI: 10.1164/Rccm.200811-1691Oc  0.314
2009 Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Skinner JT, Champion HC, Crow MT, Johns RA. Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) induces the vascular and hemodynamic changes of pulmonary hypertension American Journal of Physiology - Lung Cellular and Molecular Physiology. 296: L582-L593. PMID 19136574 DOI: 10.1152/Ajplung.90526.2008  0.39
2009 Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 250-5. PMID 19104057 DOI: 10.1073/Pnas.0804333106  0.334
2009 Bivalacqua TJ, Sussan TE, Gebska MA, Strong TD, Berkowitz DE, Biswal S, Burnett AL, Champion HC. Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction. The Journal of Urology. 181: 899-906. PMID 19095260 DOI: 10.1016/J.Juro.2008.10.062  0.5
2009 Burnett AL, Musicki B, Champion HC, Bivalacqua TJ. Chronic Phosphodiesterase Type 5 Inhibitor Therapy Reduces Priapic Activity in Transgenic Sickle Cell Mice: Restoring Nitric Oxide/Redox Balance in the Penis. Blood. 114: 576-576. DOI: 10.1182/Blood.V114.22.576.576  0.482
2009 Bivalacqua TJ, Musicki B, Champion HC, Burnett AL. EFFECT OF BONE MARROW TRANSPLANTED SICKLE HEMOGLOBIN AND HEMOLYSIS ON THE DEVELOPMENT OF PRIAPISM IN A NEW ANIMAL MODEL OF SICKLE CELL ANEMIA-ASSOCIATED PRIAPISM Journal of Urology. 181: 298-298. DOI: 10.1016/S0022-5347(09)60848-X  0.392
2009 Bivalacqua TJ, Strong TD, Schaeffer EM, Pavlovich CP, Champion HC, Burnett AL. POTENTIAL ROLE FOR NESTIN, A NEURAL STEM CELL MARKER, IN THE PATHOPHYSIOLOGY OF INJURY AND REPAIR OF THE CAVERNOUS NERVE Journal of Urology. 181: 241-241. DOI: 10.1016/S0022-5347(09)60685-6  0.396
2009 Mathai SC, Bueso M, Hummers LK, Boyce D, Lechtzin N, LePavec J, Champion H, Wigley FM, Girgis RE, Hassoun PM. N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE IS A UNIQUE MARKER OF POOR SURVIVAL IN SCLERODERMA-RELATED PULMONARY ARTERIAL HYPERTENSION Chest. 136: 54S. DOI: 10.1016/S0012-3692(16)48077-3  0.312
2008 Zhang M, Koitabashi N, Nagayama T, Rambaran R, Feng N, Takimoto E, Koenke T, O'Rourke B, Champion HC, Crow MT, Kass DA. Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes. Cellular Signalling. 20: 2231-6. PMID 18790048 DOI: 10.1016/J.Cellsig.2008.08.012  0.324
2008 Bivalacqua TJ, Guzzo TJ, Schaeffer EM, Gebska MA, Champion HC, Burnett AL, Gonzalgo ML. Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo. Urology. 72: 1169-73. PMID 18561990 DOI: 10.1016/J.Urology.2008.03.046  0.505
2008 Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, ... ... Champion HC, et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation. 117: 2626-36. PMID 18474817 DOI: 10.1161/Circulationaha.107.737031  0.375
2008 Tankersley CG, Champion HC, Takimoto E, Gabrielson K, Bedja D, Misra V, El-Haddad H, Rabold R, Mitzner W. Exposure to inhaled particulate matter impairs cardiac function in senescent mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R252-63. PMID 18448608 DOI: 10.1152/Ajpregu.00697.2007  0.306
2008 Moens AL, Vrints CJ, Claeys MJ, Timmermans JP, Champion HC, Kass DA. Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1971-7. PMID 18375715 DOI: 10.1152/Ajpheart.91503.2007  0.358
2008 Moens AL, Champion HC, Claeys MJ, Tavazzi B, Kaminski PM, Wolin MS, Borgonjon DJ, Van Nassauw L, Haile A, Zviman M, Bedja D, Wuyts FL, Elsaesser RS, Cos P, Gabrielson KL, et al. High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury. Circulation. 117: 1810-9. PMID 18362233 DOI: 10.1161/Circulationaha.107.725481  0.308
2008 Grigoryev DN, Mathai SC, Fisher MR, Girgis RE, Zaiman AL, Housten-Harris T, Cheadle C, Gao L, Hummers LK, Champion HC, Garcia JG, Wigley FM, Tuder RM, Barnes KC, Hassoun PM. Identification of candidate genes in scleroderma-related pulmonary arterial hypertension. Translational Research : the Journal of Laboratory and Clinical Medicine. 151: 197-207. PMID 18355767 DOI: 10.1016/J.Trsl.2007.12.010  0.342
2008 Ryoo S, Gupta G, Benjo A, Lim HK, Camara A, Sikka G, Lim HK, Sohi J, Santhanam L, Soucy K, Tuday E, Baraban E, Ilies M, Gerstenblith G, Nyhan D, ... ... Champion HC, et al. Endothelial arginase II: a novel target for the treatment of atherosclerosis. Circulation Research. 102: 923-32. PMID 18309100 DOI: 10.1161/Circresaha.107.169573  0.361
2008 Strong TD, Gebska MA, Champion HC, Burnett AL, Bivalacqua TJ. Stem and endothelial progenitor cells in erection biology. International Journal of Impotence Research. 20: 243-54. PMID 18256677 DOI: 10.1038/Sj.Ijir.3901635  0.485
2008 Zaiman AL, Podowski M, Medicherla S, Gordy K, Xu F, Zhen L, Shimoda LA, Neptune E, Higgins L, Murphy A, Chakravarty S, Protter A, Sehgal PB, Champion HC, Tuder RM. Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 177: 896-905. PMID 18202349 DOI: 10.1164/Rccm.200707-1083Oc  0.335
2008 Strong TD, Gebska MA, Burnett AL, Champion HC, Bivalacqua TJ. Endothelium-specific gene and stem cell-based therapy for erectile dysfunction. Asian Journal of Andrology. 10: 14-22. PMID 18087639 DOI: 10.1111/J.1745-7262.2008.00362.X  0.465
2008 Hemnes AR, Zaiman A, Champion HC. PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L24-33. PMID 17965319 DOI: 10.1152/Ajplung.00245.2007  0.371
2008 Michelakis ED, Champion HC. Editors' Note: Pulmonary vascular diseases Circulation. 118: 1115-1116. DOI: 10.1161/Circulationaha.108.808303  0.341
2008 Bivalacqua TJ, Strong TD, Sussan T, Biswal S, Burnett AL, Champion HC. SILDENAFIL CITRATE INHIBITS SUPEROXIDE FORMATION AND RESTORES ENDOTHELIAL FUNCTION IN A MOUSE MODEL OF SECOND-HAND SMOKE INDUCED ERECTILE DYSFUNCTION Journal of Urology. 179: 338-338. DOI: 10.1016/S0022-5347(08)60990-8  0.464
2008 Bivalacqua TJ, Musicki B, Champion HC, Burnett AL. PUTATIVE MECHANISMS OF SILDENAFIL'S PREVENTION OF PRIAPISM IN TRANSGENIC SICKLE CELL MICE: ROLE OF eNOS UNCOUPLING AND PHOSPHORYLATION Journal of Urology. 179: 279-279. DOI: 10.1016/S0022-5347(08)60811-3  0.436
2008 Strong TD, Gebska M, Champion HC, Burnett AL, Bivalacqua TJ. EFFECT OF BILATERAL CAVERNOUS NERVE INJURY ON NITRIC OXIDE AND RHO-KINASE SIGNALING IN A RAT MODEL OF POST- RADICAL PROSTATECTOMY ERECTILE DYSFUNCTION Journal of Urology. 179: 232-232. DOI: 10.1016/S0022-5347(08)60668-0  0.471
2007 Nossaman BD, Bivalacqua TJ, Champion HC, Baber SR, Kadowitz PJ. Analysis of vasodilator responses to peroxynitrite in the hindlimb vascular bed of the cat. Journal of Cardiovascular Pharmacology. 50: 358-66. PMID 18049302 DOI: 10.1097/Fjc.0B013E31811242Cd  0.813
2007 Kass DA, Champion HC, Beavo JA. Phosphodiesterase type 5: expanding roles in cardiovascular regulation. Circulation Research. 101: 1084-95. PMID 18040025 DOI: 10.1161/Circresaha.107.162511  0.357
2007 Strong TD, Champion HC, Kadowitz PJ, Bivalacqua TJ. Reply: potential differentiation of human mesenchymal stem cell transplanted in rat corpus cavernosum toward endothelial or smooth muscle cells. International Journal of Impotence Research. 19: 530. PMID 17786157 DOI: 10.1038/Sj.Ijir.3901585  0.587
2007 Kass DA, Takimoto E, Nagayama T, Champion HC. Phosphodiesterase regulation of nitric oxide signaling. Cardiovascular Research. 75: 303-14. PMID 17467673 DOI: 10.1016/J.Cardiores.2007.02.031  0.37
2007 Takimoto E, Belardi D, Tocchetti CG, Vahebi S, Cormaci G, Ketner EA, Moens AL, Champion HC, Kass DA. Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5. Circulation. 115: 2159-67. PMID 17420342 DOI: 10.1161/Circulationaha.106.643536  0.354
2007 Bivalacqua TJ, Kendirci M, Champion HC, Hellstrom WJG, Andersson KE, Hedlund P. Dysregulation of cGMP-dependent protein kinase 1 (PKG-1) impairs erectile function in diabetic rats: Influence of in vivo gene therapy of PKG1α Bju International. 99: 1488-1494. PMID 17355372 DOI: 10.1111/J.1464-410X.2007.06794.X  0.509
2007 Forfia PR, Lee M, Tunin RS, Mahmud M, Champion HC, Kass DA. Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart. Journal of the American College of Cardiology. 49: 1079-88. PMID 17349888 DOI: 10.1016/J.Jacc.2006.08.066  0.389
2007 Girgis RE, Mozammel S, Champion HC, Li D, Peng X, Shimoda L, Tuder RM, Johns RA, Hassoun PM. Regression of chronic hypoxic pulmonary hypertension by simvastatin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1105-10. PMID 17277047 DOI: 10.1152/Ajplung.00411.2006  0.379
2007 Kapur NK, Deming CB, Kapur S, Bian C, Champion HC, Donahue JK, Kass DA, Rade JJ. Hemodynamic modulation of endocardial thromboresistance. Circulation. 115: 67-75. PMID 17190863 DOI: 10.1161/Circulationaha.106.640698  0.335
2007 Hsu LL, Champion HC, Campbell-Lee SA, Bivalacqua TJ, Manci EA, Diwan BA, Schimel DM, Cochard AE, Wang X, Schechter AN, Noguchi CT, Gladwin MT. Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood. 109: 3088-98. PMID 17158223 DOI: 10.1182/Blood-2006-08-039438  0.545
2007 Bivalacqua TJ, Liu T, Musicki B, Champion HC, Burnett AL. Endothelial Nitric Oxide Synthase Keeps Erection Regulatory Function Balance in the Penis European Urology. 51: 1732-1740. PMID 17113219 DOI: 10.1016/J.Eururo.2006.10.061  0.49
2007 Mathai SC, Girgis RE, Fisher MR, Champion HC, Housten-Harris T, Zaiman A, Hassoun PM. Additon of sildenafil to bosentan monotherapy in pulmonary arterial hypertension European Respiratory Journal. 29: 469-475. PMID 17079256 DOI: 10.1183/09031936.00081706  0.308
2007 Bivalacqua TJ, Burnett AL, Hellstrom WJ, Champion HC. Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1340-51. PMID 17071735 DOI: 10.1152/Ajpheart.00121.2005  0.524
2007 Bivalacqua TJ, Deng W, Kendirci M, Usta MF, Robinson C, Taylor BK, Murthy SN, Champion HC, Hellstrom WJ, Kadowitz PJ. Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1278-90. PMID 17071732 DOI: 10.1152/Ajpheart.00685.2006  0.705
2007 Bilchick KC, Duncan JG, Ravi R, Takimoto E, Champion HC, Gao WD, Stull LB, Kass DA, Murphy AM. Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function. American Journal of Physiology. Heart and Circulatory Physiology. 292: H318-25. PMID 16936010 DOI: 10.1152/Ajpheart.00283.2006  0.32
2007 Bivalacqua TJ, Musicki B, Hsu LL, Gladwin MT, Champion HC, Burnett AL. 675: Phosphodiesterase Type 5 Inhibitor Therapy Corrects “Nitric Oxide” Imbalance in Sickle Cell Anemia-Associated Priapism Journal of Urology. 177: 226-226. DOI: 10.1016/S0022-5347(18)30915-7  0.416
2006 Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism. The Journal of Sexual Medicine. 3: 1077-84. PMID 17100941 DOI: 10.1111/J.1743-6109.2006.00333.X  0.426
2006 Kendirci M, Teloken PE, Champion HC, Hellstrom WJ, Bivalacqua TJ. Gene therapy for erectile dysfunction: fact or fiction? European Urology. 50: 1208-22. PMID 16950560 DOI: 10.1016/J.Eururo.2006.08.007  0.476
2006 Fisher MR, Mathai SC, Champion HC, Girgis RE, Housten-Harris T, Hummers L, Krishnan JA, Wigley F, Hassoun PM. Clinical differences between idiopathic and scleroderma-related pulmonary hypertension Arthritis and Rheumatism. 54: 3043-3050. PMID 16947776 DOI: 10.1002/Art.22069  0.328
2006 Yamaji-Kegan K, Su Q, Angelini DJ, Champion HC, Johns RA. Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2 American Journal of Physiology - Lung Cellular and Molecular Physiology. 291: L1159-L1168. PMID 16891392 DOI: 10.1152/Ajplung.00168.2006  0.368
2006 Hemnes AR, Champion HC. Sildenafil, a PDE5 inhibitor, in the treatment of pulmonary hypertension Expert Review of Cardiovascular Therapy. 4: 293-300. PMID 16716091 DOI: 10.1586/14779072.4.3.293  0.392
2006 Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism Urology. 67: 1043-1048. PMID 16698365 DOI: 10.1016/J.Urology.2005.11.045  0.449
2006 Hurt KJ, Sezen SF, Champion HC, Crone JK, Palese MA, Huang PL, Sawa A, Luo X, Musicki B, Snyder SH, Burnett AL. Alternatively spliced neuronal nitric oxide synthase mediates penile erection. Proceedings of the National Academy of Sciences of the United States of America. 103: 3440-3. PMID 16488973 DOI: 10.1073/Pnas.0511326103  0.373
2006 Jin L, Liu T, Lagoda GA, Champion HC, Bivalacqua TJ, Burnett AL. Elevated RhoA/Rho-kinase activity in the aged rat penis: Mechanism for age-associated erectile dysfunction Faseb Journal. 20: 536-538. PMID 16396994 DOI: 10.1096/Fj.05-4232Fje  0.501
2006 White AR, Ryoo S, Li D, Champion HC, Steppan J, Wang D, Nyhan D, Shoukas AA, Hare JM, Berkowitz DE. Knockdown of arginase I restores NO signaling in the vasculature of old rats. Hypertension. 47: 245-51. PMID 16380531 DOI: 10.1161/01.Hyp.0000198543.34502.D7  0.386
2006 Bivalacqua TJ, Champion HC, Mason W, Burnett AL. 1202: Long-Term Phosphodiesterase Type 5 Inhibitor Therapy Reduces Priapic Activity in Transgenic Sickle Cell Mice Journal of Urology. 175: 387-387. DOI: 10.1016/S0022-5347(18)33427-X  0.428
2005 Bivalacqua TJ, Usta MF, Kendirci M, Pradhan L, Alvarez X, Champion HC, Kadowitz PJ, Hellstrom WJ. Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy. The Journal of Sexual Medicine. 2: 187-97; discussion 1. PMID 16422885 DOI: 10.1111/J.1743-6109.2005.20228_1.X  0.608
2005 Bivalacqua TJ, Musicki B, Usta MF, Champion HC, Kadowitz PJ, Burnett AL, Hellstrom WJ. Endothelial nitric oxide synthase gene therapy for erectile dysfunction. Current Pharmaceutical Design. 11: 4059-67. PMID 16378511 DOI: 10.2174/138161205774913345  0.622
2005 Musicki B, Champion HC, Becker RE, Kramer MF, Liu T, Sezen SF, Burnett AL. In vivo analysis of chronic phosphodiesterase-5 inhibition with sildenafil in penile erectile tissues: No tachyphylaxis effect Journal of Urology. 174: 1493-1496. PMID 16145478 DOI: 10.1097/01.Ju.0000173006.47623.2C  0.338
2005 Wilson A, Zhou W, Champion HC, Alber S, Tang ZL, Kennel S, Watkins S, Huang L, Pitt B, Li S. Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 510-8. PMID 15953766 DOI: 10.1016/J.Ymthe.2005.04.005  0.339
2005 Girgis RE, Champion HC, Diette GB, Johns RA, Permutt S, Sylvester JT. Decreased exhaled nitric oxide in pulmonary arterial hypertension: Response to Bosentan therapy American Journal of Respiratory and Critical Care Medicine. 172: 352-357. PMID 15879413 DOI: 10.1164/Rccm.200412-1684Oc  0.378
2005 Musicki B, Champion HC, Becker RE, Liu T, Kramer MF, Burnett AL. Erection capability is potentiated by long-term sildenafil treatment: Role of blood flow-induced endothelial nitric-oxide synthase phosphorylation Molecular Pharmacology. 68: 226-232. PMID 15851653 DOI: 10.1124/Mol.104.010678  0.357
2005 Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. The Journal of Clinical Investigation. 115: 1221-31. PMID 15841206 DOI: 10.1172/Jci21968  0.37
2005 Wittstein IS, Thiemann DR, Lima JA, Baughman KL, Schulman SP, Gerstenblith G, Wu KC, Rade JJ, Bivalacqua TJ, Champion HC. Neurohumoral features of myocardial stunning due to sudden emotional stress. The New England Journal of Medicine. 352: 539-48. PMID 15703419 DOI: 10.1056/Nejmoa043046  0.393
2005 Champion HC, Bivalacqua TJ, Takimoto E, Kass DA, Burnett AL. Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism Proceedings of the National Academy of Sciences of the United States of America. 102: 1661-1666. PMID 15668387 DOI: 10.1073/Pnas.0407183102  0.504
2005 Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nature Medicine. 11: 214-22. PMID 15665834 DOI: 10.1038/Nm1175  0.336
2005 Segers P, Georgakopoulos D, Afanasyeva M, Champion HC, Judge DP, Millar HD, Verdonck P, Kass DA, Stergiopulos N, Westerhof N. Conductance catheter-based assessment of arterial input impedance, arterial function, and ventricular-vascular interaction in mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1157-64. PMID 15604134 DOI: 10.1152/Ajpheart.00414.2004  0.33
2005 Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA. cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism Circulation Research. 96: 100-109. PMID 15576651 DOI: 10.1161/01.Res.0000152262.22968.72  0.341
2005 Hsu LL, Champion HC, Manci E, Diwan B, Schimel D, Cochard A, Wang X, Holtzclaw JD, Schechter A, Noguchi CT, Gladwin M. Spontaneous Pulmonary Hypertension in Transgenic Sickle Cell Mice - Hemodynamics and Histology Suggest Abnormal Nitric Oxide Production and Scavenging. Blood. 106: 208-208. DOI: 10.1182/Blood.V106.11.208.208  0.398
2005 Bivalacqua TJ, Liu T, Champion HC, Burnett AL. 1041: Endothelial Nitric Oxide Synthase is a Homeostatic Regulator of RHOA/RHO-Kinase Activity in the Penis Journal of Urology. 173: 282-283. DOI: 10.1016/S0022-5347(18)35197-8  0.49
2005 Champion HC, Bivalacqua TJ, Kass DA, Burnett AL. 1040: Priapism in Sickle Cell Transgenic Mice is Associated with PDE5 Downregulation: Further Support for PDE5 Dysregulation in Priapism Journal of Urology. 173: 282-282. DOI: 10.1016/S0022-5347(18)35196-6  0.404
2005 Nagoshi T, Matsui T, Aoyama T, Li L, Kass DA, Champion HC, Anthony R. 46. In Vivo Adenoviral Gene Transfer of Activated PI3-Kinase Rescues Cardiac Dysfunction and Injury Induced by Ischemia-Reperfusion after Chronic Cardiac Akt Activation Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.074  0.311
2004 Bivalacqua TJ, Deng W, Champion HC, Hellstrom WJ, Kadowitz PJ. Gene therapy techniques for the delivery of endothelial nitric oxide synthase to the corpora cavernosa for erectile dysfunction. Methods in Molecular Biology (Clifton, N.J.). 279: 173-85. PMID 15199245 DOI: 10.1385/1-59259-807-2:173  0.7
2004 Bivalacqua TJ, Champion HC, Usta MF, Cellek S, Chitaley K, Webb RC, Lewis RL, Mills TM, Hellstrom WJ, Kadowitz PJ. RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 101: 9121-6. PMID 15184671 DOI: 10.1073/Pnas.0400520101  0.599
2004 Bivalacqua TJ, Usta MF, Champion HC, Leungwattanakij S, Dabisch PA, McNamara DB, Kadowitz PJ, Hellstrom WJ. Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats. International Journal of Impotence Research. 16: 21-9. PMID 14963467 DOI: 10.1038/Sj.Ijir.3901054  0.763
2004 Champion HC, Georgakopoulos D, Takimoto E, Isoda T, Wang Y, Kass DA. Modulation of in vivo cardiac function by myocyte-specific nitric oxide synthase-3. Circulation Research. 94: 657-63. PMID 14752030 DOI: 10.1161/01.Res.0000119323.79644.20  0.363
2004 Nossaman BD, Dabisch PA, Liles JT, Baber SR, Champion HC, Kaye AD, Feng CJ, Anwar M, Bivalacqua TJ, Santiago JA, De Witt BJ, Kadowitz PJ. Peroxynitrite does not impair pulmonary and systemic vascular responses. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 455-62. PMID 14715677 DOI: 10.1152/Japplphysiol.01159.2002  0.803
2004 Bivalacqua TJ, Champion HC, Takimoto E, Kass D, Burnett AL. 1423: PDE5 Dysregulation in Penile Erectile Tissue: Mechanism of Priapism Journal of Urology. 171: 375-375. DOI: 10.1016/S0022-5347(18)38648-8  0.401
2004 Bivalacqua TJ, Usta MF, Champion HC, Deng W, Kadowitz PJ, Hellstrom WJ. 1417: Mesenchymal Stem Cells Alone or Modified with ENOS Restore Erectile Function in the Aged Rat: Cell-Based Gene Therapy for Erectile Dysfunction Journal of Urology. 171: 373-373. DOI: 10.1016/S0022-5347(18)38642-7  0.661
2004 Bivalacqua TJ, Usta, MF, Champion HC, Cellek S, Mills TM, Lewis RW, Hellstrom WJ. 1411: Rhoa/Rho-Kinase Suppresses Endothelial Nitric Oxide Synthase in the Penis: Novel Mechanism for Diabetic-Associated Erectile Dysfunction Journal of Urology. 171: 371-372. DOI: 10.1016/S0022-5347(18)38636-1  0.493
2003 Bivalacqua TJ, Usta MF, Champion HC, Kadowitz PJ, Hellstrom WJ. Endothelial dysfunction in erectile dysfunction: role of the endothelium in erectile physiology and disease. Journal of Andrology. 24: S17-37. PMID 14581492 DOI: 10.1002/J.1939-4640.2003.Tb02743.X  0.621
2003 Berkowitz DE, White R, Li D, Minhas KM, Cernetich A, Kim S, Burke S, Shoukas AA, Nyhan D, Champion HC, Hare JM. Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels. Circulation. 108: 2000-6. PMID 14517171 DOI: 10.1161/01.Cir.0000092948.04444.C7  0.343
2003 Baber SR, Champion HC, Bivalacqua TJ, Hyman AL, Kadowitz PJ. Role of cyclooxygenase-2 in the generation of vasoactive prostanoids in the rat pulmonary and systemic vascular beds. Circulation. 108: 896-901. PMID 12900348 DOI: 10.1161/01.Cir.0000084536.87322.Bb  0.798
2003 Teng X, Li D, Champion HC, Johns RA. FIZZ1/RELMα, a novel hypoxia-induced mitogenic factor in lung with vasoconstrictive and angiogenic properties Circulation Research. 92: 1065-1067. PMID 12714564 DOI: 10.1161/01.Res.0000073999.07698.33  0.403
2003 Paolocci N, Katori T, Champion HC, St John ME, Miranda KM, Fukuto JM, Wink DA, Kass DA. Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 5537-42. PMID 12704230 DOI: 10.1073/Pnas.0937302100  0.329
2003 Bivalacqua TJ, Usta MF, Champion HC, Adams D, Namara DB, Abdel-Mageed AB, Kadowitz PJ, Hellstrom WJ. Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats. The Journal of Urology. 169: 1911-7. PMID 12686872 DOI: 10.1097/01.Ju.0000051881.14239.4A  0.627
2003 Champion HC, Skaf MW, Hare JM. Role of nitric oxide in the pathophysiology of heart failure Heart Failure Reviews. 8: 35-46. PMID 12652158 DOI: 10.1023/A:1022142904202  0.302
2003 Leungwattanakij S, Bivalacqua TJ, Usta MF, Yang DY, Hyun JS, Champion HC, Abdel-Mageed AB, Hellstrom WJ. Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum. Journal of Andrology. 24: 239-45. PMID 12634311 DOI: 10.1002/J.1939-4640.2003.Tb02668.X  0.466
2003 Champion HC, Bivalacqua TJ, Pierce RL, Murphy WA, Coy DH, Hyman AL, Kadowitz PJ. Responses to human CGRP, ADM, and PAMP in human thymic arteries. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R531-7. PMID 12529288 DOI: 10.1152/Ajpregu.00337.2002  0.666
2003 Bivalacqua TJ, Armstrong JS, Biggerstaff J, Abdel-Mageed AB, Kadowitz PJ, Hellstrom WJ, Champion HC. Gene transfer of extracellular SOD to the penis reduces O2-* and improves erectile function in aged rats. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1408-21. PMID 12505874 DOI: 10.1152/Ajpheart.00770.2002  0.616
2003 White AR, Berkowitz DE, Li D, Champion HC, Kim S, Burke S, Shoukas A, Nyhan D, Hare JM. Upregulation of arginase mediates endothelial dysfunction in aging blood vessels Journal of the American College of Cardiology. 41: 270. DOI: 10.1016/S0735-1097(03)82266-0  0.333
2003 Bivalacqua TJ, Champion HC. Role of arginase in the pulmonary vascular response to chronic hypoxia in the mouse: Augmentation of responses by in vivo gene transfer Journal of the American College of Cardiology. 41: 223. DOI: 10.1016/S0735-1097(03)81621-2  0.541
2002 Chitaley K, Bivalacqua TJ, Champion HC, Usta MF, Hellstrom WJG, Mills TM, Clinton Webb R. Adeno-associated viral gene transfer of dominant negative RhoA enhances erectile function in rats Biochemical and Biophysical Research Communications. 298: 427-432. PMID 12413959 DOI: 10.1016/S0006-291X(02)02458-0  0.526
2002 Champion HC, Bivalacqua TJ, Greenberg SS, Giles TD, Hyman AL, Kadowitz PJ. Adenoviral gene transfer of endothelial nitric-oxide synthase (eNOS) partially restores normal pulmonary arterial pressure in eNOS-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 13248-53. PMID 12237402 DOI: 10.1073/Pnas.182225899  0.638
2002 Bivalacqua TJ, Champion HC, Shah MK, De Witt BJ, Inscho EW, Kadowitz PJ. Comparative responses to alpha,beta-methylene-ATP in cat pulmonary, mesenteric, and hindquarter vascular beds. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 1287-95. PMID 12235027 DOI: 10.1152/Japplphysiol.00262.2002  0.595
2002 Bivalacqua TJ, Hyman AL, Kadowitz PJ, Paolocci N, Kass DA, Champion HC. Role of calcitonin gene-related peptide (CGRP) in chronic hypoxia-induced pulmonary hypertension in the mouse. Influence of gene transfer in vivo. Regulatory Peptides. 108: 129-33. PMID 12220736 DOI: 10.1016/S0167-0115(02)00100-3  0.638
2002 Bivalacqua TJ, Champion HC, Lambert DG, Kadowitz PJ. Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R1696-709. PMID 12010752 DOI: 10.1152/Ajpregu.00394.2001  0.649
2002 Ortiz LA, Champion HC, Lasky JA, Gambelli F, Gozal E, Hoyle GW, Beasley MB, Hyman AL, Friedman M, Kadowitz PJ. Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-kappaB and AP-1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1209-21. PMID 12003776 DOI: 10.1152/Ajplung.00144.2001  0.507
2002 Champion HC, Bivalacqua TJ, Zadina JE, Kastin AJ, Hyman AL, Kadowitz PJ. Role of nitric oxide in mediating vasodilator responses to opioid peptides in the rat. Clinical and Experimental Pharmacology & Physiology. 29: 229-32. PMID 11906489 DOI: 10.1046/J.1440-1681.2002.03634.X  0.673
2002 Bivalacqua TJ, Hellstrom WJG, Kadowitz PJ, Champion HC, Burnett AL. Increased expression of arginase II in human diabetic corpus cavernosum: In diabetic-associated erectile dysfunction International Journal of Impotence Research. 14: 204. DOI: 10.1038/sj.ijir.3900849  0.493
2002 Champion HC, Bivalacqua TJ, Kass D, Hyman AL, Kadowitz PJ. In vivo gene transfer of enos and sod reduces superoxide formation in angiotensin II-treated mice Journal of the American College of Cardiology. 39: 251. DOI: 10.1016/S0735-1097(02)81123-8  0.579
2001 Bivalacqua TJ, Champion HC, Hyman AL, McNamara DB, Kadowitz PJ. Analysis of responses to angiotensin II in the mouse. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 2: S48-S53. PMID 28095236 DOI: 10.1177/14703203010020010801  0.622
2001 Shah MK, Champion HC, Bivalacqua TJ, Kadowitz PJ. Differential responses to ATPgammaS in the mesenteric and hindlimb vascular bed of the cat. Life Sciences. 69: 2561-71. PMID 11693263 DOI: 10.1016/S0024-3205(01)01336-4  0.66
2001 Bivalacqua TJ, Champion HC, Abdel-Mageed AB, Kadowitz PJ, Hellstrom WJ. Gene transfer of prepro-calcitonin gene-related peptide restores erectile function in the aged rat. Biology of Reproduction. 65: 1371-7. PMID 11673252 DOI: 10.1095/Biolreprod65.5.1371  0.615
2001 Shah MK, Bivalacqua TJ, Champion HC, Kadowitz PJ. Vasodilator responses to ATP and UTP are cAMP dependent in the mesenteric vascular bed of the cat. Journal of Cardiovascular Pharmacology and Therapeutics. 6: 287-95. PMID 11584335 DOI: 10.1177/107424840100600309  0.644
2001 Champion HC, Pierce RL, Bivalacqua TJ, Murphy WA, Coy DH, Kadowitz PJ. Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat. Peptides. 22: 1427-34. PMID 11514024 DOI: 10.1016/S0196-9781(01)00482-X  0.68
2001 Bivalacqua TJ, Champion HC, De Witt BJ, Saavedra JE, Hrabie JA, Keefer LK, Kadowitz PJ. Analysis of vasodilator responses to novel nitric oxide donors in the hindquarters vascular bed of the cat. Journal of Cardiovascular Pharmacology. 38: 120-9. PMID 11444495 DOI: 10.1097/00005344-200107000-00013  0.67
2001 Sikka SC, Champion HC, Bivalacqua TJ, Estrada LS, Wang R, Rajasekaran M, Aggarwal BB, Hellstrom WJG. Role of genitourinary inflammation in infertility: Synergistic effect of lipopolysaccharide and interferon-γ on human spermatozoa International Journal of Andrology. 24: 136-141. PMID 11380702 DOI: 10.1046/J.1365-2605.2001.00279.X  0.406
2001 Bivalacqua TJ, Hellstrom WJ, Kadowitz PJ, Champion HC. Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction. Biochemical and Biophysical Research Communications. 283: 923-7. PMID 11350073 DOI: 10.1006/Bbrc.2001.4874  0.583
2001 Bivalacqua TJ, Champion HC, Leungwattanakij S, Yang DY, Hyun JS, Abdel-Mageed AB, Sikka SC, Kadowitz PJ, Hellstrom WJ. Evaluation of nitric oxide synthase and arginase in the induction of a Peyronie's-like condition in the rat. Journal of Andrology. 22: 497-506. PMID 11330651 DOI: 10.1002/J.1939-4640.2001.Tb02207.X  0.611
2001 Doherty PC, Bivalacqua TJ, Champion HC, Kadowitz PJ, Greenwood-Van Meerveld B, Berzetei-Gurske I, Hellstrom WJ. Direct effects of selective type 5 phosphodiesterase inhibitors alone or with other vasodilators on the erectile response in cats. The Journal of Urology. 165: 1004-9. PMID 11176530 DOI: 10.1016/S0022-5347(05)66592-5  0.603
2001 Bivalacqua T, Heistad D, Kadowitz P, Kass D, Champion H. In vivo Adenoviral Gene Transfer of CGRP and Related Peptides to the Rat and Mouse The Scientific World Journal. 1: 6-6. DOI: 10.1100/Tsw.2001.404  0.657
2001 Bivalacqua TJ, Champion HC, Hyman AL, McNamara DB, Kadowitz PJ. Analysis of responses to angiotensin II in the mouse Jraas - Journal of the Renin-Angiotensin-Aldosterone System. 2: S48-S53.  0.414
2000 Mazzocchi G, Rossi GP, Malendowicz LK, Champion HC, Nussdorfer GG. Endothelin-1[1-31], acting as an ETA-receptor selective agonist, stimulates proliferation of cultured rat zona glomerulosa cells Febs Letters. 487: 194-198. PMID 11150508 DOI: 10.1016/S0014-5793(00)02352-8  0.325
2000 Bivalacqua TJ, Champion HC, Hellstrom WJ, Kadowitz PJ. Pharmacotherapy for erectile dysfunction. Trends in Pharmacological Sciences. 21: 484-9. PMID 11121838 DOI: 10.1016/S0165-6147(00)01587-X  0.576
2000 Hugghins SY, Champion HC, Cheng G, Kadowitz PJ, Jeter JR. Vasorelaxant responses to endomorphins, nociceptin, albuterol, and adrenomedullin in isolated rat aorta Life Sciences. 67: 471-476. PMID 11003057 DOI: 10.1016/S0024-3205(00)00631-7  0.544
2000 Bivalacqua TJ, Champion HC, Mehta YS, Abdel-Mageed AB, Sikka SC, Ignarro LJ, Kadowitz PJ, Hellstrom WJ. Adenoviral gene transfer of endothelial nitric oxide synthase (eNOS) to the penis improves age-related erectile dysfunction in the rat. International Journal of Impotence Research. 12: S8-17. PMID 11002394 DOI: 10.1038/Sj.Ijir.3900556  0.631
2000 De Witt BJ, Garrison EA, Champion HC, Kadowitz PJ. L-163,491 is a partial angiotensin AT1 receptor agonist in the hindquarters vascular bed of the cat European Journal of Pharmacology. 404: 213-219. PMID 10980281 DOI: 10.1016/S0014-2999(00)00612-9  0.55
2000 Champion HC, Kadowitz PJ. Vasodilator responses to ATP and UTP are not dependent on nitric oxide release, K+(ATP) channel activation, or the release of vasodilator prostaglandins in the hindlimb vascular bed of the cat Canadian Journal of Physiology and Pharmacology. 78: 612-621. PMID 10958161 DOI: 10.1139/Y00-021  0.537
2000 Bivalacqua TJ, Champion HC, Purohit SK, Murphy WA, Coy DH, Kadowitz PJ, Hellstrom WJ. Nitric oxide-mediated erectile effects of galantide but not galanin in vivo. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 4: 94-102. PMID 10835289 DOI: 10.1006/Niox.2000.0274  0.661
2000 Bivalacqua TJ, Diner EK, Novak TE, Vohra Y, Sikka SC, Champion HC, Kadowitz PJ, Hellstrom WJ. A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression. The Journal of Urology. 163: 1992-8. PMID 10799245 DOI: 10.1016/S0022-5347(05)67616-1  0.608
2000 Champion HC, Bivalacqua TJ, Toyoda K, Heistad DD, Hyman AL, Kadowitz PJ. In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse. Circulation. 101: 923-30. PMID 10694533 DOI: 10.1161/01.Cir.101.8.923  0.654
2000 Champion HC, Villnave DJ, Tower A, Kadowitz PJ, Hyman AL. A novel right-heart catheterization technique for in vivo measurement of vascular responses in lungs of intact mice American Journal of Physiology - Heart and Circulatory Physiology. 278: H8-H15. PMID 10644578 DOI: 10.1152/Ajpheart.2000.278.1.H8  0.56
1999 Mazzocchi G, Albertin G, Andreis PG, Neri G, Malendowicz LK, Champion HC, Bahçelioglu M, Kadowitz PJ, Nussdorfer GG. Distribution, functional role, and signaling mechanism of adrenomedullin receptors in the rat adrenal gland Peptides. 20: 1479-1487. PMID 10698124 DOI: 10.1016/S0196-9781(99)00159-X  0.465
1999 Champion HC, Bivalacqua TJ, Zadina JE, Kastin AJ, Kadowitz PJ. Vasodilator responses to the endomorphin peptides, but not nociceptin/OFQ, are mediated by nitric oxide release. Annals of the New York Academy of Sciences. 897: 165-72. PMID 10676445 DOI: 10.1111/J.1749-6632.1999.Tb07888.X  0.66
1999 Bivalacqua TJ, Champion HC, Wang R, Kadowitz PJ, Doherty PC, Hellstrom WJ. Feline penile erection induced by transurethral administration of sodium nitroprusside. Urological Research. 27: 432-6. PMID 10651131 DOI: 10.1007/S002400050132  0.606
1999 Champion HC, Nussdorfer GG, Kadowitz PJ. Structure-activity relationships of adrenomedullin in the circulation and adrenal gland Regulatory Peptides. 85: 1-8. PMID 10588445 DOI: 10.1016/S0167-0115(99)00025-7  0.501
1999 Bivalacqua TJ, Dalal A, Champion HC, Kadowitz PJ. Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice. The American Journal of Physiology. 277: E838-47. PMID 10567010 DOI: 10.1152/Ajpendo.1999.277.5.E838  0.625
1999 Bivalacqua TJ, Champion HC, Rajasekaran M, Sikka SC, Kadowitz PJ, Doherty PC, Hellstrom WJ. Potentiation of erectile response and cAMP accumulation by combination of prostaglandin E1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE 4). The Journal of Urology. 162: 1848-55. PMID 10524946 DOI: 10.1016/S0022-5347(05)68249-3  0.64
1999 Champion HC, Bivalacqua TJ, Lambert DG, Abassi RA, Kadowitz PJ. Analysis of vasoconstrictor responses to histamine in the hindlimb vascular bed of the rabbit. The American Journal of Physiology. 277: R1179-87. PMID 10516260 DOI: 10.1152/Ajpregu.1999.277.4.R1179  0.632
1999 Champion HC, Bivalacqua TJ, Hyman AL, Ignarro LJ, Hellstrom WJ, Kadowitz PJ. Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat. Proceedings of the National Academy of Sciences of the United States of America. 96: 11648-52. PMID 10500231 DOI: 10.1073/Pnas.96.20.11648  0.664
1999 Champion HC, Bivalacqua TJ, D'Souza FM, Ortiz LA, Jeter JR, Toyoda K, Heistad DD, Hyman AL, Kadowitz PJ. Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses. Circulation Research. 84: 1422-32. PMID 10381895 DOI: 10.1161/01.Res.84.12.1422  0.665
1999 Belloni AS, Rossi GP, Andreis PG, Aragona F, Champion HC, Kadowitz PJ, Murphy WA, Coy DH, Nussdorfer GG. Proadrenomedullin N-terminal 20 peptide (PAMP), acting through PAMP(12- 20)-sensitive receptors, inhibits Ca2+-dependent, agonist-stimulated secretion of human adrenal glands Hypertension. 33: 1185-1189. PMID 10334809 DOI: 10.1161/01.Hyp.33.5.1185  0.507
1999 Champion HC, Bivalacqua TJ, Wang R, Kadowitz PJ, Keefer LK, Saavedra JE, Hrabie JA, Doherty PC, Hellstrom WJ. Induction of penile erection by intracavernosal and transurethral administration of novel nitric oxide donors in the cat. The Journal of Urology. 161: 2013-9. PMID 10332492 DOI: 10.1016/S0022-5347(05)68875-1  0.625
1999 Belloni AS, Andreis PG, Meneghelli V, Champion HC, Kadowitz PJ, Coy DH, Murphy WA, Nussdorfer GG. Adrenomedullin and calcitonin gene-related peptide (CGRP) interact with a common receptor of the CGRP1 subtype in the human adrenal zona glomerulosa Endocrine Research. 25: 29-34. PMID 10098591 DOI: 10.1080/07435809909066127  0.404
1999 Champion HC, Kadowitz PJ. Vasodepressor responses to [D-Ala2]-endomorphin 2 (TAPP) are mediated by an L-NAME-sensitive mechanism in the rat Journal of Cardiovascular Pharmacology. 33: 280-284. PMID 10028937 DOI: 10.1097/00005344-199902000-00015  0.593
1999 CHAMPION H. In vivo gene-transfer of calcitonin gene-related peptide (CGRP) reduces hypoxia-induced pulmonary hypertension in the mouse. American Journal of Hypertension. 12: 43. DOI: 10.1016/S0895-7061(99)80135-6  0.344
1998 Champion HC, Czapla MA, Kadowitz PJ. Responses to angiotensin peptides are mediated by ATreceptors in the rat. American Journal of Physiology. Endocrinology and Metabolism. 274: E115-E123. PMID 29590986 DOI: 10.1152/ajpendo.1998.274.1.E115  0.522
1998 Champion HC, Kadowitz PJ. d-[Ala]endomorphin 2 and endomorphin 2 have nitric oxide-dependent vasodilator activity in rats. American Journal of Physiology. Heart and Circulatory Physiology. 274: H1690-H1697. PMID 29586504 DOI: 10.1152/ajpheart.1998.274.5.H1690  0.559
1998 Hyman AL, Hao Q, Tower A, Kadowitz PJ, Champion HC, Gumusel B, Lippton H. Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats. American Journal of Physiology. Heart and Circulatory Physiology. 274: H1218-H1229. PMID 29586014 DOI: 10.1152/ajpheart.1998.274.4.H1218  0.505
1998 Gumusel B, Hao Q, Hyman AL, Kadowitz PJ, Champion HC, Chang JK, Mehta JL, Lippton H. Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats. American Journal of Physiology. Heart and Circulatory Physiology. 274: H1255-H1263. PMID 29586004 DOI: 10.1152/ajpheart.1998.274.4.H1255  0.577
1998 Champion HC, Bivalacqua TJ, Rauchwarger A, McWilliams SM, McNamara DB, Kadowitz PJ. Analysis of Vasodepressor Responses to Nociceptin and Nociceptin Analogs in the Systemic Vascular Bed of the Anesthetized Rabbit In Vivo. Journal of Cardiovascular Pharmacology and Therapeutics. 3: 247-252. PMID 10684505 DOI: 10.1177/107424849800300308  0.647
1998 Belloni AS, Andreis PG, Rossi GP, Champion HC, Kadowitz PJ, Murphy WA, Coy DH, Nussdorfer GG. Structure-activity relationships of adrenomedullin in the adrenal gland Endocrine Research. 24: 729-730. PMID 9888567 DOI: 10.3109/07435809809032677  0.509
1998 Champion HC, Pierce RL, Kadowitz PJ. Nociceptin, a novel endogenous ligand for the ORL1 receptor, dilates isolated resistance arteries from the rat Regulatory Peptides. 78: 69-74. PMID 9879748 DOI: 10.1016/S0167-0115(98)00117-7  0.566
1998 Belloni AS, Andreis PG, Rossi GP, Mingrino A, Champion HC, Kadowitz PJ, Murphy WA, Coy DH, Nussdorfer GG. Inhibitory effect of adrenomedullin (ADM) on the aldosterone response of human adrenocortical cells to angiotensin-II: Role of ADM(22-52)-sensitive receptors Life Sciences. 63: 2313-2321. PMID 9877221 DOI: 10.1016/S0024-3205(98)00520-7  0.499
1998 Champion HC, Bivalacqua TJ, Wang R, Hellstrom WJ, Kadowitz PJ. [Tyr1]-nociceptin and nociceptin have similar naloxone-insensitive erectile activity in the cat. Journal of Andrology. 19: 747-53. PMID 9876026 DOI: 10.1002/J.1939-4640.1998.Tb02084.X  0.637
1998 Champion HC, Bivalacqua TJ, Friedman DE, Zadina JE, Kastin AJ, Kadowitz PJ. Nitric oxide release mediates vasodilator responses to endomorphin 1 but not nociceptin/OFQ in the hindquarters vascular bed of the rat. Peptides. 19: 1595-602. PMID 9864068 DOI: 10.1016/S0196-9781(98)00110-7  0.679
1998 Belloni AS, Meneghelli V, Champion HC, Murray WA, Coy DH, Kadowitz PJ, Nussdorfer GG. Autoradiographic evidence that zona glomerulosa and capsular vessels of the human adrenal cortex are provided with different subtypes of adrenomedullin receptors Peptides. 19: 1581-1584. PMID 9864066 DOI: 10.1016/S0196-9781(98)00111-9  0.513
1998 Bivalacqua TJ, Rajasekaran M, Champion HC, Wang R, Sikka SC, Kadowitz PJ, Hellstrom WJ. The influence of castration on pharmacologically induced penile erection in the cat. Journal of Andrology. 19: 551-7. PMID 9796614 DOI: 10.1002/J.1939-4640.1998.Tb02056.X  0.606
1998 Champion HC, Bivalacqua TJ, Lambert DG, McWilliams SM, Zadina JE, Kastin AJ, Kadowitz PJ. Endomorphin 1 and 2, the endogenous mu-opioid agonists, produce biphasic changes in systemic arterial pressure in the cat. Life Sciences. 63: PL131-6. PMID 9740318 DOI: 10.1016/S0024-3205(98)00335-X  0.634
1998 Champion HC, Kadowitz PJ. Influence of nimodipine on vasoconstrictor responses in the hindquarters vascular bed of the cat Journal of Pharmacy and Pharmacology. 50: 673-680. PMID 9680080 DOI: 10.1111/J.2042-7158.1998.Tb06904.X  0.554
1998 McNamara DB, Champion HC, Kadowitz PJ. Pharmacologic management of peripheral vascular disease Surgical Clinics of North America. 78: 447-464. PMID 9673656 DOI: 10.1016/S0039-6109(05)70325-X  0.459
1998 Champion HC, Zadina JE, Kastin AJ, Kadowitz PJ. Endomorphin 1 and 2 have vasodepressor activity in the anesthetized mouse. Peptides. 19: 925-9. PMID 9663459 DOI: 10.1016/S0196-9781(98)00026-6  0.581
1998 Champion HC, Estrada LS, Estrada LN, Filep JG, Kadowitz PJ. Analysis of effects of bosentan (Ro 47-0203), a nonpeptide endothelin ET(A)/ET(B) receptor antagonist, in the hind-limb vascular bed of the cat Canadian Journal of Physiology and Pharmacology. 76: 141-147. PMID 9635152 DOI: 10.1139/Y98-001  0.59
1998 Lambert DG, Champion HC, Kadowitz PJ. Inhibitory effects of candesartan on responses to angiotensin peptides in the hindquarters vascular bed of the cat Canadian Journal of Physiology and Pharmacology. 76: 133-140. PMID 9635151 DOI: 10.1139/Y98-002  0.564
1998 Gumusel B, Hao Q, Hyman AL, Kadowitz PJ, Champion HC, Chang JK, Mehta JL, Lippton H. Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats. The American Journal of Physiology. 274: H1255-63. PMID 9575929 DOI: 10.1152/Ajpheart.1998.274.4.H1255  0.621
1998 Hyman AL, Hao Q, Tower A, Kadowitz PJ, Champion HC, Gumusel B, Lippton H. Novel catheterization technique for the in vivo measurement of pulmonary vascular responses in rats. The American Journal of Physiology. 274: H1218-29. PMID 9575925 DOI: 10.1152/Ajpheart.1998.274.4.H1218  0.564
1998 Champion HC, Kadowitz PJ. R-(-)-alpha-methyl-histamine has nitric oxide-mediated vasodilator activity in the mesenteric vascular bed of the cat. European Journal of Pharmacology. 343: 209-16. PMID 9570469 DOI: 10.1016/S0014-2999(97)01525-2  0.524
1998 Czapla MA, Champion HC, Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kadowitz PJ. Endomorphin 1 and 2, endogenous mu-opioid agonists, decrease systemic arterial pressure in the rat. Life Sciences. 62: PL175-9. PMID 9519803 DOI: 10.1016/S0024-3205(98)00048-4  0.551
1998 Champion HC, Czapla MA, Kadowitz PJ. Responses to angiotensin peptides are mediated by AT1 receptors in the rat. The American Journal of Physiology. 274: E115-23. PMID 9458756 DOI: 10.1152/Ajpendo.1998.274.1.E115  0.58
1998 Champion HC, Kadowitz PJ. [Tyr1]-nociceptin has naloxone-insensitive vasodilator activity in the hindquarters vascular bed of the rat. Life Sciences. 61: PL 403-8. PMID 9416781 DOI: 10.1016/S0024-3205(97)01013-8  0.586
1998 Champion HC, Kadowitz PJ. D-[Ala2]endomorphin 2 and endomorphin 2 have nitric oxide-dependent vasodilator activity in rats American Journal of Physiology - Heart and Circulatory Physiology. 43: H1690-H1697. DOI: 10.1152/Ajpheart.1998.274.5.H1690  0.611
1998 Lambert DG, Champion HC, Kadowitz PJ. Inhibitory effects of candesartan on responses to angiotensin peptides in the hindquarters vascular bed of the cat Canadian Journal of Physiology and Pharmacology. 76: 133-140. DOI: 10.1139/y98-002  0.505
1998 Champion HC, Estrada LS, Estrada LN, Filep JG, Kadowitz PJ. Analysis of effects of bosentan (Ro 47-0203), a nonpeptide endothelin ETA/ETB receptor antagonist, in the hind-limb vascular bed of the cat Canadian Journal of Physiology and Pharmacology. 76: 141-147. DOI: 10.1139/y98-001  0.543
1997 Garrison EA, Champion HC, Kadowitz PJ. [Pro,d-Ala]angiotensin I has rapid onset vasoconstrictor activity in the cat. American Journal of Physiology. Endocrinology and Metabolism. 273: E1059-E1064. PMID 29585406 DOI: 10.1152/ajpendo.1997.273.6.E1059  0.486
1997 Garrison EA, Champion HC, Kadowitz PJ. [Pro11,D-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat. The American Journal of Physiology. 273: E1059-64. PMID 9435519 DOI: 10.1152/Ajpendo.1997.273.6.E1059  0.556
1997 Champion HC, Zadina JE, Kastin AJ, Kadowitz PJ. The endogenous mu-opioid agonists, endomorphin 1 and 2, have vasodilator activity in the hindquarters vascular bed of the rat. Life Sciences. 61: PL 409-15. PMID 9416782 DOI: 10.1016/S0024-3205(97)01029-1  0.577
1997 Champion HC, Akers DL, Santiago JA, Lambert DG, McNamara DB, Kadowitz PJ. Analysis of responses to human synthetic adrenomedullin and calcitonin gene-related peptides in the hindlimb vascular bed of the cat. Molecular and Cellular Biochemistry. 176: 5-11. PMID 9406138 DOI: 10.1023/A:1006888107952  0.546
1997 Czapla MA, Champion HC, Kadowitz PJ. Decreases in systemic arterial and hindquarters perfusion pressure in response to nociceptin are not inhibited by naloxone in the rat. Peptides. 18: 1197-200. PMID 9396061 DOI: 10.1016/S0196-9781(97)00178-2  0.568
1997 Champion HC, Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kadowitz PJ. Endomorphin 1 and 2, endogenous ligands for the mu-opioid receptor, decrease cardiac output, and total peripheral resistance in the rat. Peptides. 18: 1393-7. PMID 9392842 DOI: 10.1016/S0196-9781(97)00210-6  0.566
1997 Champion HC, Santiago JA, Czapla MA, Bivalacqua TJ, Ilgenfritz C, Kadowitz PJ. Comparison of responses to T-kinin and bradykinin in the mesenteric vascular bed of the cat. Peptides. 18: 1357-64. PMID 9392837 DOI: 10.1016/S0196-9781(97)00197-6  0.629
1997 Champion HC, Kadowitz PJ. Analysis of the effects of candesartan in the mesenteric vascular bed of the cat. Hypertension (Dallas, Tex. : 1979). 30: 1260-6. PMID 9369285 DOI: 10.1161/01.Hyp.30.5.1260  0.541
1997 DeWitt BJ, Champion HC, Marrone JR, McNamara DB, Giles TD, Greenberg SS, Kadowitz PJ. Differential effects of L-N5-(1-iminoethyl)-ornithine on tone and endothelium-dependent vasodilator responses. The American Journal of Physiology. 273: L588-94. PMID 9316493 DOI: 10.1152/Ajplung.1997.273.3.L588  0.518
1997 Czapla MA, Champion HC, Kadowitz PJ. Nociceptin, an endogenous ligand for the ORL1 receptor, has vasodilator activity in the hindquarters vascular bed of the rat. Peptides. 18: 793-5. PMID 9285926 DOI: 10.1016/S0196-9781(97)00014-4  0.594
1997 Champion HC, Kadowitz PJ. NO release and the opening of K+ATP channels mediate vasodilator responses to histamine in the cat. The American Journal of Physiology. 273: H928-37. PMID 9277512 DOI: 10.1152/Ajpheart.1997.273.2.H928  0.519
1997 Champion HC, Lambert DG, McWilliams SM, Shah MK, Murphy WA, Coy DH, Kadowitz PJ. Comparison of responses to rat and human adrenomedullin in the hindlimb vascular bed of the cat. Regulatory Peptides. 70: 161-5. PMID 9272628 DOI: 10.1016/S0167-0115(97)01003-3  0.613
1997 Champion HC, Wang R, Hellstrom WJ, Kadowitz PJ. Nociceptin, a novel endogenous ligand for the ORL1 receptor, has potent erectile activity in the cat. The American Journal of Physiology. 273: E214-9. PMID 9252499 DOI: 10.1152/Ajpendo.1997.273.1.E214  0.576
1997 Champion HC, Kadowitz PJ. Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism. The American Journal of Physiology. 273: R414-22. PMID 9249580 DOI: 10.1152/Ajpregu.1997.273.1.R414  0.573
1997 Champion HC, Czapla MA, Kadowitz PJ. Nociceptin, an endogenous ligand for the ORL1 receptor, decreases cardiac output and total peripheral resistance in the rat. Peptides. 18: 729-32. PMID 9213368 DOI: 10.1016/S0196-9781(97)00003-X  0.572
1997 Champion HC, Czapla MA, Friedman DE, Lambert DG, Murphy WA, Coy DH, Kadowitz PJ. Tone-dependent vasodilator responses to proadrenomedullin NH2-terminal 20 peptide in the hindquarters vascular bed of the rat. Peptides. 18: 513-9. PMID 9210169 DOI: 10.1016/S0196-9781(96)00348-8  0.59
1997 Champion HC, Zadina JE, Kastin AJ, Hackler L, Ge LJ, Kadowitz PJ. The endogenous mu-opioid receptor agonists endomorphins 1 and 2 have novel hypotensive activity in the rabbit. Biochemical and Biophysical Research Communications. 235: 567-70. PMID 9207197 DOI: 10.1006/Bbrc.1997.6843  0.547
1997 Champion HC, Kadowitz PJ. [Tyr1]-nociceptin, a novel nociceptin analog, decreases systemic arterial pressure by a naloxone-insensitive mechanism in the rat. Biochemical and Biophysical Research Communications. 234: 309-12. PMID 9177265 DOI: 10.1006/Bbrc.1997.6629  0.571
1997 Champion HC, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal 20 peptide has direct vasodilator activity in the cat. The American Journal of Physiology. 272: R1047-54. PMID 9140000 DOI: 10.1152/Ajpregu.1997.272.4.R1047  0.588
1997 Champion HC, Friedman DE, Lambert DG, Murphy WA, Coy DH, Kadowitz PJ. Adrenomedullin (16-31) has pressor activity in the rat but not the cat Peptides. 18: 133-136. PMID 9114462 DOI: 10.1016/S0196-9781(96)00251-3  0.58
1997 Champion HC, Kadowitz PJ. Nociceptin, an endogenous ligand for the ORL1 receptor, has novel hypotensive activity in the rat. Life Sciences. 60: PL 241-5. PMID 9096263 DOI: 10.1016/S0024-3205(97)00087-8  0.583
1997 Santiago JA, Champion HC, Kadowitz PJ. T-kinin has endothelium-dependent vasodilator activity in the cat. The American Journal of Physiology. 272: H1491-8. PMID 9087628 DOI: 10.1152/Ajpheart.1997.272.3.H1491  0.543
1997 Fry RC, Champion HC, Lawrence TC, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal peptide (PAMP)(12-20) has vasodepressor activity in the rat and cat. Life Sciences. 60: PL161-7. PMID 9064471 DOI: 10.1016/S0024-3205(97)00007-6  0.517
1997 Champion HC, Santiago JA, Murphy WA, Coy DH, Kadowitz PJ. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. The American Journal of Physiology. 272: R234-42. PMID 9039014 DOI: 10.1152/Ajpregu.1997.272.1.R234  0.605
1997 Champion HC, Wang R, Shenassa BB, Murphy WA, Coy DH, Hellstrom WJ, Kadowitz PJ. Adrenomedullin induces penile erection in the cat. European Journal of Pharmacology. 319: 71-5. PMID 9030900 DOI: 10.1016/S0014-2999(96)00924-7  0.563
1997 Champion HC, Wang R, Santiago JA, Murphy WA, Coy DH, Kadowitz PJ, Hellstrom WJG. Comparison of Responses to Adrenomedullin and Calcitonin Gene‐Related Peptide in the Feline Erection Model Journal of Andrology. 18: 513-521. DOI: 10.1002/J.1939-4640.1997.Tb01966.X  0.593
1996 DeWitt BJ, Cheng DY, McMahon TJ, Marrone JR, Champion HC, Kadowitz PJ. Effects of U-37883A, a vascular selective K(ATP)/+ channel antagonist, in the pulmonary and hindlimb circulation American Journal of Physiology - Lung Cellular and Molecular Physiology. 271. PMID 8997262 DOI: 10.1152/Ajplung.1996.271.6.L924  0.349
1996 Champion HC, Santiago JA, Garrison EA, Cheng DY, Coy DH, Murphy WA, Ascuitto RJ, Ross-Ascuitto NT, Mcnamara DB, Kadowitz PJ. Analysis of cardiovascular responses to PACAP-27, PACAP-38, and vasoactive intestinal polypeptide Annals of the New York Academy of Sciences. 805: 429-442. PMID 8993422 DOI: 10.1111/J.1749-6632.1996.Tb17502.X  0.595
1996 Champion HC, Erickson CC, Simoneaux ML, Bivalacqua TJ, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal 20 peptide has cAMP-mediated vasodilator activity in the mesenteric vascular bed of the cat. Peptides. 17: 1379-87. PMID 8971935 DOI: 10.1016/S0196-9781(96)00240-9  0.662
1996 Champion HC, Fry RC, Murphy WA, Coy DH, Kadowitz PJ. Catecholamine release mediates pressor effects of adrenomedullin-(15- 22) in the rat Hypertension. 28: 1041-1046. PMID 8952594 DOI: 10.1161/01.Hyp.28.6.1041  0.579
1996 Champion HC, Garrison EA, Estrada LS, Potter JM, Kadowitz PJ. Analysis of responses to angiotensin I and angiotensin I-(3-10) in the mesenteric vascular bed of the cat. European Journal of Pharmacology. 309: 251-9. PMID 8874148 DOI: 10.1016/0014-2999(96)00355-X  0.57
1996 Champion HC, Duperier CD, Fitzgerald WE, Lambert DG, Murphy WA, Coy DH, Kadowitz PJ. [MPR14]-rADM(14-50), a novel analog of adrenomedullin, possesses potent vasodilator activity in the hindlimb vascular bed of the cat. Life Sciences. 59: PL1-7. PMID 8684260 DOI: 10.1016/0024-3205(96)00258-5  0.589
1995 Santiago JA, Garrison EA, Champion HC, Smith RE, Del Rio O, Kadowitz PJ. Analysis of responses to kallidin, DABK, and DAK in feline hindlimb vascular bed. The American Journal of Physiology. 269: H2057-64. PMID 8594917 DOI: 10.1152/Ajpheart.1995.269.6.H2057  0.571
1995 Santiago JA, Garrison E, Purnell WL, Smith RE, Champion HC, Coy DH, Murphy WA, Kadowitz PJ. Comparison of responses to adrenomedullin and adrenomedullin analogs in the mesenteric vascular bed of the cat. European Journal of Pharmacology. 272: 115-8. PMID 7713143 DOI: 10.1016/0014-2999(94)00693-2  0.581
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