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Carmela Molinaro, Ph.D. - Publications

Affiliations: 
2002 Université de Montréal, Montréal, Canada 
Area:
stereoselective synthesis of organic compounds
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wong N, Petronijević F, Hong AY, Linghu X, Kelly SM, Hou H, Cravillion T, Lim NK, Robinson SJ, Han C, Molinaro C, Sowell CG, Gosselin F. Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338. Organic Letters. PMID 31668077 DOI: 10.1021/Acs.Orglett.9B03481  0.437
2019 Molinaro C, Phillips EM, Xiang B, Milczek EM, Shevlin M, Balsells J, Ceglia S, Chen J, Chen L, Chen Q, Fei Z, Hoerrner S, Qi J, de Lera Ruiz M, Tan L, et al. Synthesis of a CGRP Receptor Antagonist via a Asymmetric Synthesis of 3-Fluoro-4-aminopiperidine. The Journal of Organic Chemistry. PMID 31124362 DOI: 10.1021/acs.joc.9b00569  0.445
2019 Song ZJ, Maligres P, Molinaro C, Humphrey G, Fritzen J, Wilson J, Chen Y. Preparation of 2-(2H-Tetrazol-2-yl)benzoic Acids via Regioselective Cu(I) Catalyzed N2 Arylation of Tetrazole Organic Process Research & Development. 23: 2354-2361. DOI: 10.1021/acs.oprd.9b00243  0.287
2016 Thaisrivongs DA, Miller SP, Molinaro C, Chen Q, Song ZJ, Tan L, Chen L, Chen W, Lekhal A, Pulicare SK, Xu Y. Synthesis of Verubecestat, a BACE1 Inhibitor for the Treatment of Alzheimer's Disease. Organic Letters. 18: 5780-5783. PMID 27934506 DOI: 10.1021/acs.orglett.6b01793  0.326
2016 Bungard CJ, Williams PD, Ballard JE, Bennett DJ, Beaulieu C, Bahnck-Teets C, Carroll SS, Chang RK, Dubost DC, Fay JF, Diamond TL, Greshock TJ, Hao L, Holloway MK, Felock PJ, ... ... Molinaro C, et al. Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group. Acs Medicinal Chemistry Letters. 7: 702-7. PMID 27437081 DOI: 10.1021/Acsmedchemlett.6B00135  0.221
2015 Molinaro C, Scott JP, Shevlin M, Wise C, Ménard A, Gibb A, Junker EM, Lieberman D. Catalytic, asymmetric, and stereodivergent synthesis of non-symmetric β,β-diaryl-α-amino acids. Journal of the American Chemical Society. 137: 999-1006. PMID 25523503 DOI: 10.1021/ja511872a  0.328
2012 Molinaro C, Bulger PG, Lee EE, Kosjek B, Lau S, Gauvreau D, Howard ME, Wallace DJ, O'Shea PD. CRTH2 antagonist MK-7246: a synthetic evolution from discovery through development. The Journal of Organic Chemistry. 77: 2299-309. PMID 22335767 DOI: 10.1021/jo202620r  0.37
2011 Zaghdane H, Boyd M, Colucci J, Simard D, Berthelette C, Leblanc Y, Wang Z, Houle R, Lévesque JF, Molinaro C, Hamel M, Stocco R, Sawyer N, Sillaots S, Gervais F, et al. New indole amide derivatives as potent CRTH2 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 3471-4. PMID 21515053 DOI: 10.1016/j.bmcl.2011.03.085  0.279
2011 Ouellet SG, Roy A, Molinaro C, Angelaud R, Marcoux JF, O'Shea PD, Davies IW. Preparative scale synthesis of the biaryl core of anacetrapib via a ruthenium-catalyzed direct arylation reaction: unexpected effect of solvent impurity on the arylation reaction. The Journal of Organic Chemistry. 76: 1436-9. PMID 21284400 DOI: 10.1021/Jo1018574  0.525
2011 Molinaro C, Shultz S, Roy A, Lau S, Trinh T, Angelaud R, O'Shea PD, Abele S, Cameron M, Corley E, Funel JA, Steinhuebel D, Weisel M, Krska S. A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate. The Journal of Organic Chemistry. 76: 1062-71. PMID 21250716 DOI: 10.1021/Jo102070E  0.4
2011 Simard D, Leblanc Y, Berthelette C, Zaghdane MH, Molinaro C, Wang Z, Gallant M, Lau S, Thao T, Hamel M, Stocco R, Sawyer N, Sillaots S, Gervais F, Houle R, et al. Azaindoles as potent CRTH2 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 841-5. PMID 21185722 DOI: 10.1016/j.bmcl.2010.11.084  0.229
2011 Gallant M, Beaulieu C, Berthelette C, Colucci J, Crackower MA, Dalton C, Denis D, Ducharme Y, Friesen RW, Guay D, Gervais FG, Hamel M, Houle R, Krawczyk CM, Kosjek B, ... ... Molinaro C, et al. Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases. Bioorganic & Medicinal Chemistry Letters. 21: 288-93. PMID 21106375 DOI: 10.1016/j.bmcl.2010.11.015  0.249
2010 Molinaro C, Guilbault AA, Kosjek B. Resolution of 2,2-disubstituted epoxides via biocatalytic azidolysis. Organic Letters. 12: 3772-5. PMID 20681610 DOI: 10.1021/ol101406k  0.467
2010 Gosselin F, Britton RA, Davies IW, Dolman SJ, Gauvreau D, Hoerrner RS, Hughes G, Janey J, Lau S, Molinaro C, Nadeau C, O'Shea PD, Palucki M, Sidler R. A practical synthesis of 5-lipoxygenase inhibitor MK-0633. The Journal of Organic Chemistry. 75: 4154-60. PMID 20486715 DOI: 10.1021/Jo100561U  0.443
2010 Charette AB, Molinaro C, Brochu C. ChemInform Abstract: Catalytic Asymmetric Cyclopropanation of Allylic Alcohols with Titanium-TADDOLate: Scope of the Cyclopropanation Reaction. Cheminform. 33: no-no. DOI: 10.1002/chin.200217043  0.475
2010 Charette AB, Molinaro C, Brochu C. ChemInform Abstract: Stability, Reactivity, Solution, and Solid-State Structure of Halomethylzinc Alkoxides. Cheminform. 33: no-no. DOI: 10.1002/chin.200216044  0.485
2009 Molinaro C, Gauvreau D, Hughes G, Lau S, Lauzon S, Angelaud R, O'Shea PD, Janey J, Palucki M, Hoerrner SR, Raab CE, Sidler RR, Belley M, Han Y. Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310. The Journal of Organic Chemistry. 74: 6863-6. PMID 19663395 DOI: 10.1021/Jo901267X  0.391
2007 Molinaro C, Mowat J, Gosselin F, O'Shea PD, Marcoux JF, Angelaud R, Davies IW. A practical synthesis of alpha-aryl methyl ketones via a transition-metal-free Meerwein arylation. The Journal of Organic Chemistry. 72: 1856-8. PMID 17263583 DOI: 10.1021/Jo062483G  0.338
2004 Molinaro C, Jamison TF. Catalytic reductive coupling of epoxides and aldehydes: epoxide-ring opening precedes carbonyl reduction. Angewandte Chemie (International Ed. in English). 44: 129-32. PMID 15599916 DOI: 10.1002/Anie.200461705  0.574
2004 Miller KM, Luanphaisarnnont T, Molinaro C, Jamison TF. Alkene-directed, nickel-catalyzed alkyne coupling reactions. Journal of the American Chemical Society. 126: 4130-1. PMID 15053602 DOI: 10.1021/Ja0491735  0.667
2003 Molinaro C, Jamison TF. Nickel-catalyzed reductive coupling of alkynes and epoxides. Journal of the American Chemical Society. 125: 8076-7. PMID 12837057 DOI: 10.1021/Ja0361401  0.638
2003 Lebel H, Marcoux JF, Molinaro C, Charette AB. Stereoselective cyclopropanation reactions. Chemical Reviews. 103: 977-1050. PMID 12683775 DOI: 10.1021/Cr010007E  0.691
2003 Miller KM, Molinaro C, Jamison TF. Catalytic reductive carbon-carbon bond-forming reactions of alkynes Tetrahedron Asymmetry. 14: 3619-3625. DOI: 10.1016/J.Tetasy.2003.07.010  0.643
2001 Charette AB, Molinaro C, Brochu C. Catalytic asymmetric cyclopropanation of allylic alcohols with titanium-TADDOLate: scope of the cyclopropanation reaction. Journal of the American Chemical Society. 123: 12168-75. PMID 11734015 DOI: 10.1021/Ja0108382  0.655
2001 Charette AB, Molinaro C, Brochu C. Stability, reactivity, solution, and solid-state structure of halomethylzinc alkoxides. Journal of the American Chemical Society. 123: 12160-7. PMID 11734014 DOI: 10.1021/Ja010837+  0.635
2001 Charette AB, Molinaro C. Enantioselective cyclopropanation using dioxaborolane ligands Acs Symposium Series. 783: 136-147.  0.499
2000 Charette AB, Marcoux JF, Molinaro C, Beauchemin A, Brochu C, Isabel E. Preparation, solid-state structure, and synthetic applications of isolable and storable haloalkylzinc reagents [1] Journal of the American Chemical Society. 122: 4508-4509. DOI: 10.1021/Ja994371V  0.643
1998 Charette AB, Juteau H, Lebel H, Molinaro C. Enantioselective cyclopropanation of allylic alcohols with dioxaborolane ligands: Scope and synthetic applications Journal of the American Chemical Society. 120: 11943-11952. DOI: 10.1021/Ja982055V  0.686
1996 Bratty J, Ferbeyre G, Molinaro C, Cedergren R. Stimulation of mitotic recombination upon transcription from the yeast GAL1 promoter but not from other RNA polymerase I, II and III promoters. Current Genetics. 30: 381-8. PMID 8929389 DOI: 10.1007/S002940050146  0.499
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