Toshiharu Suzuki - Publications

Affiliations: 
University of Tokyo, Bunkyō-ku, Tōkyō-to, Japan 
 Hokkaido University, Sapporo-shi, Hokkaidō, Japan 
Area:
Alzheimers Disease

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hata S, Kano K, Kikuchi K, Kinoshita S, Sobu Y, Saito H, Saito T, Saido TC, Sano Y, Taru H, Aoki J, Komano H, Tomita T, Natori S, Suzuki T. Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid. Journal of Neurochemistry. PMID 34379812 DOI: 10.1111/jnc.15490  0.76
2021 Fujita Y, Kano K, Kishino S, Nagao T, Shen X, Sato C, Hatakeyama H, Ota Y, Niibori S, Nomura A, Kikuchi K, Yasuno W, Takatori S, Kikuchi K, Sano Y, ... ... Suzuki T, et al. Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer's disease mouse model. Scientific Reports. 11: 9749. PMID 33980877 DOI: 10.1038/s41598-021-88870-9  0.467
2020 Gotoh N, Saito Y, Hata S, Saito H, Ojima D, Murayama C, Shigeta M, Abe T, Konno D, Matsuzaki F, Suzuki T, Yamamoto T. Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of Alcadein α-deficient mice. The Journal of Biological Chemistry. PMID 32467230 DOI: 10.1074/Jbc.Ra119.012386  0.438
2020 Seita Y, Morimura T, Watanabe N, Iwatani C, Tsuchiya H, Nakamura S, Suzuki T, Yanagisawa D, Tsukiyama T, Nakaya M, Okamura E, Muto M, Ema M, Nishimura M, Tooyama I. Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein. Journal of Alzheimer's Disease : Jad. PMID 32250299 DOI: 10.3233/Jad-191081  0.368
2020 Kakuda N, Yamaguchi H, Akazawa K, Hata S, Suzuki T, Hatsuta H, Murayama S, Funamoto S, Ihara Y. γ-Secretase activity is associated with Braak Senile Plaque stages. The American Journal of Pathology. PMID 32201261 DOI: 10.1016/J.Ajpath.2020.02.009  0.363
2019 Hata S, Hu A, Piao Y, Nakaya T, Taru H, Morishima-Kawashima M, Murayama S, Nishimura M, Suzuki T. Enhanced amyloid-β generation by γ-secretase complex in detergent-resistant membrane microdomains with reduced cholesterol levels. Human Molecular Genetics. PMID 31841137 DOI: 10.1093/Hmg/Ddz297  0.738
2019 Hata S, Omori C, Kimura A, Saito H, Kimura N, Gupta V, Pedrini S, Hone E, Chatterjee P, Taddei K, Kasuga K, Ikeuchi T, Waragai M, Nishimura M, Hu A, ... Suzuki T, et al. Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 5: 740-750. PMID 31754625 DOI: 10.1016/J.Trci.2019.09.015  0.387
2019 Kushibiki Y, Suzuki T, Jin Y, Taru H. RIMB-1/RIM-binding protein and UNC-10/RIM redundantly regulate presynaptic localization of the voltage-gated calcium channel in . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31530643 DOI: 10.1523/Jneurosci.0506-19.2019  0.776
2019 Saito H, Hata S, Suzuki T. P1-158: PREVENTION OF NEURON FROM TOXICITY INDUCED BY Aβ42 BY P3-ALCβ PEPTIDES AND THEIR PHARMACOKINETICS IN MICE Alzheimer's & Dementia. 15: P297-P297. DOI: 10.1016/J.Jalz.2019.06.713  0.321
2019 Hata S, Kimura A, Saito H, Waragai M, Ikeuchi T, Martins RN, Kimura N, Nishimura M, Suzuki T. P3-184: ALTERED LEVELS OF P3-ALCβ PEPTIDES IN THE CSF OF AGED MONKEYS AND ALZHEIMER'S DISEASE PATIENTS Alzheimer's & Dementia. 15: P1000-P1001. DOI: 10.1016/J.Jalz.2019.06.3213  0.309
2018 Motodate R, Saito H, Sobu Y, Hata S, Saito Y, Nakaya T, Suzuki T. X11 and X11-like proteins regulate the level of extrasynaptic glutamate receptors. Journal of Neurochemistry. PMID 30411795 DOI: 10.1111/Jnc.14623  0.323
2018 Fukuyama K, Kakio S, Nakazawa Y, Kobata K, Funakoshi-Tago M, Suzuki T, Tamura H. Roasted Coffee Reduces β-amyloid Production by Increasing Proteasomal β-Secretase Degradation in Human Neuroblastoma SH-SY5Y Cells. Molecular Nutrition & Food Research. e1800238. PMID 30144352 DOI: 10.1002/Mnfr.201800238  0.317
2018 Cam M, Durieu E, Bodin M, Manousopoulou A, Koslowski S, Vasylieva N, Barnych B, Hammock BD, Bohl B, Koch P, Omori C, Yamamoto K, Hata S, Suzuki T, Karg F, et al. Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides. Journal of Alzheimer's Disease : Jad. PMID 29504531 DOI: 10.3233/Jad-170875  0.374
2017 Chiba K, Chien KY, Sobu Y, Hata S, Kato S, Nakaya T, Okada Y, Nairn AC, Kinjo M, Taru H, Wang R, Suzuki T. Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1. Molecular Biology of the Cell. PMID 29093025 DOI: 10.1091/Mbc.E17-05-0303  0.777
2017 Sobu Y, Furukori K, Chiba K, Nairn AC, Kinjo M, Hata S, Suzuki T. Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo. Molecular Biology of the Cell. PMID 29093024 DOI: 10.1091/Mbc.E17-05-0301  0.539
2017 Suzuki T, Chiba K, Shiraki Y, Sobu Y, Hata S. [P2-138]: REGULATION AND FUNCTION OF APP AS A CARGO-RECEPTOR OF KINESIN-1 IN NEURONS Alzheimer's & Dementia. 13: P659-P659. DOI: 10.1016/J.Jalz.2017.06.788  0.319
2017 Omori C, Hata S, Waragai M, Suzuki T, Yamamoto K. [P3-217]: NOVEL BIOMARKER P3-ALCα, PEPTIDES PRODUCED BY γ-SECRETASE CLEAVAGE, ALTERED IN AD PATIENTS Alzheimer's & Dementia. 13: P1021-P1021. DOI: 10.1016/J.Jalz.2017.06.1430  0.323
2017 Hata S, Kimura A, Waragai M, Ikeuchi T, Martins RN, Kimura N, Nishimura M, Suzuki T. [P3-202]: LEVEL OF P3-ALCβ PEPTIDES ALTER IN CSF OF AD PATIENTS Alzheimer's & Dementia. 13: P1013-P1013. DOI: 10.1016/J.Jalz.2017.06.1415  0.307
2017 Toyoda M, Nakaya T, Michikawa M, Suzuki T. [P3-093]: IDENTIFICATION OF APOE4-X11L REGULATED DOWNSTREAM GENES RELATED TO THE LATE-ONSET AD Alzheimer's & Dementia. 13: P969-P970. DOI: 10.1016/J.Jalz.2017.06.1303  0.318
2017 Saitoh H, Omori C, Kimura A, Waragai M, Maeda M, Hata S, Suzuki T. PROTECTIVE PROPERTY OF P3-ALCβ AGAINST A NEUROTOXICITY INDUCED BY Aβ OLIGOMER Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.019  0.315
2016 Kimura A, Hata S, Suzuki T. Alternative Selection of BACE1 Cleavage Sites in APP Harboring Protective And Pathogenic Mutations Within the Aβ Sequence. The Journal of Biological Chemistry. PMID 27687728 DOI: 10.1074/Jbc.M116.744722  0.359
2016 Portelius E, Durieu E, Bodin M, Cam M, Pannee J, Leuxe C, Mabondzo A, Oumata N, Galons H, Lee JY, Chang YT, Stϋber K, Koch P, Fontaine G, Potier MC, ... Suzuki T, et al. Specific Triazine Herbicides Induce Amyloid-β42 Production. Journal of Alzheimer's Disease : Jad. PMID 27589520 DOI: 10.3233/Jad-160310  0.373
2016 Omori C, Motodate R, Shiraki Y, Chiba K, Sobu Y, Kimura A, Nakaya T, Kondo H, Kurumiya S, Tanaka T, Yamamoto K, Nakajima M, Suzuki T, Hata S. Facilitation of brain mitochondrial activity by 5-aminolevulinic acid in a mouse model of Alzheimer's disease. Nutritional Neuroscience. 1-9. PMID 27329428 DOI: 10.1080/1028415X.2016.1199114  0.343
2016 Motodate R, Saito Y, Hata S, Suzuki T. Expression and localization of X11 family proteins in neurons. Brain Research. PMID 27268412 DOI: 10.1016/J.Brainres.2016.05.054  0.407
2016 Suzuki T, Kimura A, Hata S. P4-060: Alternative Cleavage Mechanism of Human App by Bace1 Alzheimer's & Dementia. 12: P1037-P1037. DOI: 10.1016/J.Jalz.2016.06.2150  0.321
2016 Omori C, Hata S, Waragai M, Yamamoto K, Suzuki T. P3-184: Increase of P3-ALCA38 to P3-ALCA35, Products by Γ-Secretase Cleavage, in CSF of Alzheimer's Disease Patients Alzheimer's & Dementia. 12: P891-P892. DOI: 10.1016/J.Jalz.2016.06.1844  0.311
2015 Hosono T, Mouri A, Nishitsuji K, Jung CG, Kontani M, Tokuda H, Kawashima H, Shibata H, Suzuki T, Nabehsima T, Michikawa M. Arachidonic or Docosahexaenoic Acid Diet Prevents Memory Impairment in Tg2576 Mice. Journal of Alzheimer's Disease : Jad. 48: 149-62. PMID 26401936 DOI: 10.3233/Jad-150341  0.371
2015 Kimura A, Hata S, Suzuki T. Stabilization of intracellular trafficking and metabolism of amyloid β-protein precursor and Alcadein β by apolipoprotein E. Febs Letters. 589: 2394-400. PMID 26213366 DOI: 10.1016/J.Febslet.2015.07.017  0.424
2015 Hosono T, Nishitsuji K, Nakamura T, Jung CG, Kontani M, Tokuda H, Kawashima H, Kiso Y, Suzuki T, Michikawa M. Arachidonic acid diet attenuates brain Aβ deposition in Tg2576 mice. Brain Research. 1613: 92-9. PMID 25881896 DOI: 10.1016/J.Brainres.2015.04.005  0.396
2015 Takei N, Sobu Y, Kimura A, Urano S, Piao Y, Araki Y, Taru H, Yamamoto T, Hata S, Nakaya T, Suzuki T. Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid β-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage. The Journal of Biological Chemistry. 290: 987-95. PMID 25406318 DOI: 10.1074/Jbc.M114.599852  0.814
2015 Suzuki T, Kimura A, Chiba K, Nakaya T, Hata S. Brain aging as a cause of alzheimer’s disease Aging Mechanisms: Longevity, Metabolism, and Brain Aging. 305-318. DOI: 10.1007/978-4-431-55763-0_18  0.347
2014 Preobraschenski J, Zander JF, Suzuki T, Ahnert-Hilger G, Jahn R. Vesicular glutamate transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter. Neuron. 84: 1287-301. PMID 25433636 DOI: 10.1016/j.neuron.2014.11.008  0.378
2014 Chiba K, Araseki M, Nozawa K, Furukori K, Araki Y, Matsushima T, Nakaya T, Hata S, Saito Y, Uchida S, Okada Y, Nairn AC, Davis RJ, Yamamoto T, Kinjo M, ... Suzuki T, et al. Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport. Molecular Biology of the Cell. 25: 3569-80. PMID 25165140 DOI: 10.1091/Mbc.E14-06-1111  0.797
2014 Tajes M, Eraso-Pichot A, Rubio-Moscardó F, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Guix FX, Clarimón J, Miscione GP, Boada M, Gil-Gómez G, Suzuki T, Molina H, Villà-Freixa J, Vicente R, et al. Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 41: 273-88. PMID 24614897 DOI: 10.3233/Jad-131685  0.367
2014 Morihara T, Hayashi N, Yokokoji M, Akatsu H, Silverman MA, Kimura N, Sato M, Saito Y, Suzuki T, Yanagida K, Kodama TS, Tanaka T, Okochi M, Tagami S, Kazui H, et al. Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier. Proceedings of the National Academy of Sciences of the United States of America. 111: 2638-43. PMID 24497505 DOI: 10.1073/Pnas.1307345111  0.329
2014 Omori C, Kaneko M, Nakajima E, Akatsu H, Waragai M, Maeda M, Morishima-Kawashima M, Saito Y, Nakaya T, Taru H, Yamamoto T, Asada T, Hata S, Suzuki T. Increased levels of plasma p3-alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 39: 861-70. PMID 24305499 DOI: 10.3233/Jad-131610  0.729
2013 Hoshino T, Suzuki K, Matsushima T, Yamakawa N, Suzuki T, Mizushima T. Suppression of Alzheimer's disease-related phenotypes by geranylgeranylacetone in mice. Plos One. 8: e76306. PMID 24098472 DOI: 10.1371/Journal.Pone.0076306  0.38
2013 Piao Y, Kimura A, Urano S, Saito Y, Taru H, Yamamoto T, Hata S, Suzuki T. Mechanism of intramembrane cleavage of alcadeins by γ-secretase. Plos One. 8: e62431. PMID 23658629 DOI: 10.1371/Journal.Pone.0062431  0.732
2013 Kang S, Todokoro Y, Yumen I, Shen B, Iwasaki I, Suzuki T, Miyagi A, Yoshida M, Fujiwara T, Akutsu H. 3P100 The Active-Site Structure of Thermophilic F_oF_1-ATP Synthase c-Subunit Rings in Membranes(03. Membrane proteins,Poster) Seibutsu Butsuri. 53. DOI: 10.2142/Biophys.53.S228_4  0.313
2013 Hata S, Omori C, Kaneko M, Waragai M, Urakami K, Taniguchi M, Ikeuchi T, Akatsu H, Suzuki T. P1-135: Quantitative alteration of p3-Alc peptides in CSF of people with Alzheimer's disease Alzheimer's & Dementia. 9: P199-P199. DOI: 10.1016/J.Jalz.2013.05.357  0.312
2013 Suzuki T, Matsushima T, Chiba K, Saito Y, Taru H, Hata S. O3-07-06: Neuron-specific phosphorylation of APP: The roles in APP metabolism and function Alzheimer's & Dementia. 9: P532-P532. DOI: 10.1016/J.Jalz.2013.04.278  0.722
2012 Saito Y, Inoue T, Zhu G, Kimura N, Okada M, Nishimura M, Kimura N, Murayama S, Kaneko S, Shigemoto R, Imoto K, Suzuki T. Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's disease. Molecular Neurodegeneration. 7: 50. PMID 23034178 DOI: 10.1186/1750-1326-7-50  0.322
2012 Maruta C, Saito Y, Hata S, Gotoh N, Suzuki T, Yamamoto T. Constitutive cleavage of the single-pass transmembrane protein alcadeinα prevents aberrant peripheral retention of Kinesin-1. Plos One. 7: e43058. PMID 22905201 DOI: 10.1371/Journal.Pone.0043058  0.384
2012 Kamogawa K, Kohara K, Tabara Y, Takita R, Miki T, Konno T, Hata S, Suzuki T. Potential utility of soluble p3-alcadein α plasma levels as a biomarker for sporadic Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 421-8. PMID 22571980 DOI: 10.3233/Jad-2012-120601  0.34
2012 Hata S, Taniguchi M, Piao Y, Ikeuchi T, Fagan AM, Holtzman DM, Bateman R, Sohrabi HR, Martins RN, Gandy S, Urakami K, Suzuki T. Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects. Molecular Neurodegeneration. 7: 16. PMID 22534039 DOI: 10.1186/1750-1326-7-16  0.398
2012 Matsushima T, Saito Y, Elliott JI, Iijima-Ando K, Nishimura M, Kimura N, Hata S, Yamamoto T, Nakaya T, Suzuki T. Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue. The Journal of Biological Chemistry. 287: 19715-24. PMID 22511769 DOI: 10.1074/Jbc.M111.334847  0.416
2012 Dumanis SB, Chamberlain KA, Jin Sohn Y, Jin Lee Y, Guénette SY, Suzuki T, Mathews PM, Pak DTs, Rebeck GW, Suh YH, Park HS, Hoe HS. FE65 as a link between VLDLR and APP to regulate their trafficking and processing. Molecular Neurodegeneration. 7: 9. PMID 22429478 DOI: 10.1186/1750-1326-7-9  0.325
2012 Kawano T, Araseki M, Araki Y, Kinjo M, Yamamoto T, Suzuki T. A small peptide sequence is sufficient for initiating kinesin-1 activation through part of TPR region of KLC1. Traffic (Copenhagen, Denmark). 13: 834-48. PMID 22404616 DOI: 10.1111/J.1600-0854.2012.01350.X  0.603
2012 Hoshino T, Namba T, Takehara M, Murao N, Matsushima T, Sugimoto Y, Narumiya S, Suzuki T, Mizushima T. Improvement of cognitive function in Alzheimer's disease model mice by genetic and pharmacological inhibition of the EP(4) receptor. Journal of Neurochemistry. 120: 795-805. PMID 22044482 DOI: 10.1111/J.1471-4159.2011.07567.X  0.326
2012 Matsushima T, Saito Y, Nishimura M, Kimura N, Hata S, Suzuki T. P2-153: Membrane microdomain localization of APP c-terminal fragments regulated by the phosphorylation at cytoplasmic Thr668 residue Alzheimer's & Dementia. 8: P312-P312. DOI: 10.1016/J.Jalz.2012.05.859  0.36
2012 Hata S, Konno T, Urakami K, Ikeuchi T, Akatsu H, Suzuki T. P2-047: Increase of p3-Alc peptides in the CSF and plasma of sporadic Alzheimer's disease patients Alzheimer's & Dementia. 8: P279-P280. DOI: 10.1016/J.Jalz.2012.05.750  0.302
2012 Kanada Y, Saito Y, Nishimura M, Kimura N, Suzuki T. P4-071: Involvement of X11/X11L in Alzheimer's-related beta-amyloid generation and epileptogenesis Alzheimer's & Dementia. 8: P658-P658. DOI: 10.1016/J.Jalz.2012.05.1773  0.43
2011 Konno T, Hata S, Hamada Y, Horikoshi-Sakuraba Y, Nakaya T, Saito Y, Yamamoto T, Yamamoto T, Maeda M, Ikeuchi T, Gandy S, Akatsu H, Suzuki T. Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA system. Molecular Neurodegeneration. 6: 76. PMID 22067061 DOI: 10.1186/1750-1326-6-76  0.373
2011 Cui H, Hung AC, Klaver DW, Suzuki T, Freeman C, Narkowicz C, Jacobson GA, Small DH. Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice. Plos One. 6: e23007. PMID 21829577 DOI: 10.1371/Journal.Pone.0023007  0.381
2011 Saito Y, Akiyama M, Araki Y, Sumioka A, Shiono M, Taru H, Nakaya T, Yamamoto T, Suzuki T. Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like. Plos One. 6: e22108. PMID 21818298 DOI: 10.1371/Journal.Pone.0022108  0.813
2011 Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, ... Suzuki T, et al. Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction. Annals of Neurology. 69: 1026-31. PMID 21681798 DOI: 10.1002/Ana.22343  0.599
2011 Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T. Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5225-34. PMID 21471357 DOI: 10.1523/Jneurosci.5478-10.2011  0.367
2011 Nakazawa S, Gotoh N, Matsumoto H, Murayama C, Suzuki T, Yamamoto T. Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 59: 202-13. PMID 21339182 DOI: 10.1369/0022155410392231  0.321
2011 Suzuki T. P4-325: Intracellular trafficking and metabolism of APP regulated by novel function of X11L Alzheimer's & Dementia. 7: e24-e24. DOI: 10.1016/J.Jalz.2011.09.070  0.343
2011 Hata S, Urakami K, Taniguchi M, Akatsu H, Gandy S, Suzuki T. P3-189: Alternative gamma-secretase processing in sporadic Alzheimer's disease suggested by p3-Alc peptide, metabolic product of alcadein Alzheimer's & Dementia. 7: S577-S577. DOI: 10.1016/J.Jalz.2011.05.1630  0.34
2011 Chiba K, Nozawa K, Araseki M, Kinjo M, Taru H, Suzuki T. P3-145: Molecular mechanism of JIP1b-mediated APP association to kinesin-1 in APP transport and metabolic regulation Alzheimer's & Dementia. 7: S562-S562. DOI: 10.1016/J.Jalz.2011.05.1585  0.73
2010 Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, Taru H, Hata S, Yamamoto T, Saito Y, Suzuki T. Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain. Molecular Neurodegeneration. 5: 35. PMID 20843325 DOI: 10.1186/1750-1326-5-35  0.747
2010 Mitsuishi Y, Hasegawa H, Matsuo A, Araki W, Suzuki T, Tagami S, Okochi M, Takeda M, Roepman R, Nishimura M. Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex. The Journal of Biological Chemistry. 285: 14920-31. PMID 20299451 DOI: 10.1074/Jbc.M109.038760  0.422
2010 Kobayashi M, Akutsu H, Suzuki T, Yoshida M, Yagi H. Analysis of the open and closed conformations of the beta subunits in thermophilic F1-ATPase by solution NMR. Journal of Molecular Biology. 398: 189-99. PMID 20230835 DOI: 10.1016/J.Jmb.2010.03.013  0.316
2010 Kuruma Y, Suzuki T, Ueda T. Production of multi-subunit complexes on liposome through an E. coli cell-free expression system. Methods in Molecular Biology (Clifton, N.J.). 607: 161-71. PMID 20204856 DOI: 10.1007/978-1-60327-331-2_14  0.331
2010 Kawai T, Nakaya T, Suzuki T. Roles of the intramolecular regions of FE65 in its trans-accumulation and in p53 stabilization in the nuclear matrix of osmotically stressed cells. Febs Letters. 584: 765-9. PMID 20036665 DOI: 10.1016/J.Febslet.2009.12.040  0.375
2010 Minami SS, Sung YM, Dumanis SB, Chi SH, Burns MP, Ann EJ, Suzuki T, Turner RS, Park HS, Pak DT, Rebeck GW, Hoe HS. The cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 58-69. PMID 19720620 DOI: 10.1096/Fj.09-138123  0.307
2010 Suzuki T, Mizumaru C. P1-299: Regulation of APP α-secretase activity involved in protein palmitoylation by DHHC-12 Alzheimer's & Dementia. 6: S260-S260. DOI: 10.1016/J.Jalz.2010.05.851  0.38
2010 Shiono M, Akiyama M, Saito Y, Suzuki T. P1-247: Functional region of X11L in the regulation of APP metabolism and trafficking Alzheimer's & Dementia. 6: S245-S245. DOI: 10.1016/J.Jalz.2010.05.798  0.335
2010 Piao Y, Gotoh N, Kondo M, Saito Y, Hata S, Yamamoto T, Suzuki T. P1-222: Expression and localization of Alcadein along with X11L and APP in mouse brain Alzheimer's & Dementia. 6: S238-S238. DOI: 10.1016/J.Jalz.2010.05.773  0.312
2010 Saito Y, Inoue T, Suzuki T. P1-112: Neuronal activity and APP metabolism in the brain of X11/X11L doubly-deficient mice Alzheimer's & Dementia. 6: S207-S207. DOI: 10.1016/J.Jalz.2010.05.661  0.335
2010 Hata S, Urakami K, Fagan A, Peskind E, Akatsu H, Maeda M, Levey A, Chung KA, Montine T, Leverenz J, Goate A, Bateman R, Holtzman DM, Gandy S, Suzuki T. P3-171: Gamma-secretase dysfunction in sporadic Alzhemer's disease suggested by p3-Alc peptide, metabolic product of Alcadein Alzheimer's & Dementia. 6: S499-S500. DOI: 10.1016/J.Jalz.2010.05.1669  0.316
2009 Hata S, Fujishige S, Araki Y, Kato N, Araseki M, Nishimura M, Hartmann D, Saftig P, Fahrenholz F, Taniguchi M, Urakami K, Akatsu H, Martins RN, Yamamoto K, Maeda M, ... Suzuki T, et al. Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction. The Journal of Biological Chemistry. 284: 36024-33. PMID 19864413 DOI: 10.1074/Jbc.M109.057497  0.643
2009 Nakaya T, Kawai T, Suzuki T. Metabolic stabilization of p53 by FE65 in the nuclear matrix of osmotically stressed cells. The Febs Journal. 276: 6364-74. PMID 19796171 DOI: 10.1111/J.1742-4658.2009.07349.X  0.335
2009 Mizumaru C, Saito Y, Ishikawa T, Yoshida T, Yamamoto T, Nakaya T, Suzuki T. Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein. Journal of Neurochemistry. 111: 1213-24. PMID 19780898 DOI: 10.1111/J.1471-4159.2009.06399.X  0.481
2009 Taru H, Suzuki T. Regulation of the physiological function and metabolism of AbetaPP by AbetaPP binding proteins. Journal of Alzheimer's Disease : Jad. 18: 253-65. PMID 19584434 DOI: 10.3233/Jad-2009-1148  0.781
2009 Sano Y, Ornthanalai VG, Yamada K, Homma C, Suzuki H, Suzuki T, Murphy NP, Itohara S. X11-like protein deficiency is associated with impaired conflict resolution in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5884-96. PMID 19420255 DOI: 10.1523/Jneurosci.5756-08.2009  0.633
2009 Hoshino T, Namba T, Takehara M, Nakaya T, Sugimoto Y, Araki W, Narumiya S, Suzuki T, Mizushima T. Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor. The Journal of Biological Chemistry. 284: 18493-502. PMID 19407341 DOI: 10.1074/Jbc.M109.003269  0.356
2009 Onoue Y, Suzuki T, Davidson M, Karlsson M, Orwar O, Yoshida M, Kinosita K. A giant liposome for single-molecule observation of conformational changes in membrane proteins. Biochimica Et Biophysica Acta. 1788: 1332-40. PMID 19366590 DOI: 10.1016/J.Bbamem.2009.01.015  0.303
2009 Guix FX, Ill-Raga G, Bravo R, Nakaya T, de Fabritiis G, Coma M, Miscione GP, Villà-Freixa J, Suzuki T, Fernàndez-Busquets X, Valverde MA, de Strooper B, Muñoz FJ. Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation. Brain : a Journal of Neurology. 132: 1335-45. PMID 19251756 DOI: 10.1093/Brain/Awp023  0.431
2009 Sakuma M, Tanaka E, Taru H, Tomita S, Gandy S, Nairn AC, Nakaya T, Yamamoto T, Suzuki T. Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP. Journal of Neurochemistry. 109: 465-75. PMID 19222704 DOI: 10.1111/J.1471-4159.2009.05988.X  0.817
2009 Sano Y, Ornthanalai VG, Yamada K, Homma C, Suzuki H, Suzuki T, Murphy NP, Itohara S. X11L protein deficiency is associated with the selective impairment of motivated approach behavior and the withdrawn response to social conflict Neuroscience Research. 65: S39. DOI: 10.1016/J.Neures.2009.09.031  0.603
2009 Gandy SE, Hata S, Fujishige S, Araki Y, Kato N, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Saftig P, Hartmann D, Fahrenholz F, Yamamoto K, Martins RN, ... Suzuki T, et al. O1-06-07: Misprocessing of Multiple Transmembrane Substrates Reveals Gamma-Secretase Dysfunction in Both Familial and Sporadic Alzheimer's Diseases Alzheimer's & Dementia. 5: e3-e3. DOI: 10.1016/J.Jalz.2009.07.125  0.545
2009 Shiono M, Akiyama M, Saito Y, Yamamoto T, Suzuki T. P4-183: Regulation of intracellular APP transport by X11L Alzheimer's & Dementia. 5: P485-P485. DOI: 10.1016/J.Jalz.2009.04.750  0.328
2009 Hata S, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Fagan A, Goate A, Bateman R, Holtzman DM, Nakaya T, Gandy S, Suzuki T. P2-190: p3-Alc peptides produced by covariant processing of Alcadein and APP implicate γ-secretase dysfunction in sporadic Alzheimer's disease Alzheimer's & Dementia. 5: P316-P317. DOI: 10.1016/J.Jalz.2009.04.502  0.343
2009 Araseki M, Kawano T, Furukori K, Yamamoto T, Suzuki T. P1-159: Regulatory mechanisms of app and alcadein transport by kinesin-1 Alzheimer's & Dementia. 5: P224-P224. DOI: 10.1016/J.Jalz.2009.04.165  0.313
2009 Kondo M, Sakuma M, Saito Y, Nakaya T, Maeda M, Suzuki T. P1-158: Amyloidogenic metabolism of human APP in X11-like deficient mice brain Alzheimer's & Dementia. 5: P224-P224. DOI: 10.1016/J.Jalz.2009.04.164  0.324
2009 Matsushima T, Nakaya T, Suzuki T. P1-155: Exclusion of phosporylated APP CTFs from membrane region rich in active γ-secretase Alzheimer's & Dementia. 5: P223-P223. DOI: 10.1016/J.Jalz.2009.04.161  0.319
2009 Saito Y, Nakaya T, Suzuki T. P1-007: Aberrant localization of amyloid precursor protein in X11 and X11L- deficient mice brain Alzheimer's & Dementia. 5: P173-P174. DOI: 10.1016/J.Jalz.2009.04.010  0.385
2008 Saito Y, Sano Y, Vassar R, Gandy S, Nakaya T, Yamamoto T, Suzuki T. X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain. The Journal of Biological Chemistry. 283: 35763-71. PMID 18845544 DOI: 10.1074/Jbc.M801353200  0.626
2008 Suzuki T, Nakaya T. Regulation of amyloid beta-protein precursor by phosphorylation and protein interactions. The Journal of Biological Chemistry. 283: 29633-7. PMID 18650433 DOI: 10.1074/Jbc.R800003200  0.487
2008 Nakaya T, Kawai T, Suzuki T. Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells. The Journal of Biological Chemistry. 283: 19119-31. PMID 18468999 DOI: 10.1074/Jbc.M801827200  0.366
2008 Sumioka A, Saito Y, Sakuma M, Araki Y, Yamamoto T, Suzuki T. The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm. Experimental Cell Research. 314: 1155-62. PMID 18201694 DOI: 10.1016/J.Yexcr.2007.12.006  0.802
2008 Saito Y, Nakaya T, Suzuki T. P1-022: Inhibitory mechanism of amyloidgenic APP metabolism by X11 and X11L in brain Alzheimer's & Dementia. 4: T212-T212. DOI: 10.1016/J.Jalz.2008.05.607  0.351
2008 Suzuki T. S3-04-04: Regulation of APP trafficking and processing in neurons Alzheimer's & Dementia. 4: T155-T155. DOI: 10.1016/J.Jalz.2008.05.395  0.4
2008 Hata S, Araki Y, Urakami K, Akatsu H, Nishimura M, Gandy S, Nakaya T, Suzuki T. P3-072: Analysis of β-Alc; Alcadein processing yields fragment homologous to APP P3 peptide Alzheimer's & Dementia. 4: T539-T539. DOI: 10.1016/J.Jalz.2008.05.1636  0.549
2008 Matsushima T, Suzuki T, Nakaya T. P1-453: APP metabolism in brain of Thr668 residue mutant mice Alzheimer's & Dementia. 4: T352-T352. DOI: 10.1016/J.Jalz.2008.05.1036  0.328
2008 Furukori K, Araki Y, Taru H, Yamamoto T, Davis RJ, Suzuki T. P1-452: Analysis of axonal transport of APP in JIP1 gene-deficient mice Alzheimer's & Dementia. 4: T352-T352. DOI: 10.1016/J.Jalz.2008.05.1035  0.752
2008 Suzuki T, Wakabayashi C, Feniouk BA, Taniguchi N, Yoshida M. S1.17 Function of epsilon subunit in bacillus PS3 FOF1F0F1-ATP synthase: C-terminal helices of epsilon conduct the substrate specificity toward nucleoside triphosphates Biochimica Et Biophysica Acta. 1777. DOI: 10.1016/J.Bbabio.2008.05.055  0.307
2007 Ikin AF, Causevic M, Pedrini S, Benson LS, Buxbaum JD, Suzuki T, Lovestone S, Higashiyama S, Mustelin T, Burgoyne RD, Gandy S. Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. Molecular Neurodegeneration. 2: 23. PMID 18067682 DOI: 10.1186/1750-1326-2-23  0.6
2007 Hoshino T, Nakaya T, Homan T, Tanaka K, Sugimoto Y, Araki W, Narita M, Narumiya S, Suzuki T, Mizushima T. Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo. The Journal of Biological Chemistry. 282: 32676-88. PMID 17767011 DOI: 10.1074/Jbc.M703087200  0.395
2007 Araki Y, Kawano T, Taru H, Saito Y, Wada S, Miyamoto K, Kobayashi H, Ishikawa HO, Ohsugi Y, Yamamoto T, Matsuno K, Kinjo M, Suzuki T. The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. The Embo Journal. 26: 1475-86. PMID 17332754 DOI: 10.1038/Sj.Emboj.7601609  0.792
2007 Hoshino T, Nakaya T, Araki W, Suzuki K, Suzuki T, Mizushima T. Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. The Biochemical Journal. 402: 581-9. PMID 17132139 DOI: 10.1042/Bj20061318  0.441
2007 Feniouk BA, Suzuki T, Yoshida M. Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. The Journal of Biological Chemistry. 282: 764-72. PMID 17092944 DOI: 10.1074/Jbc.M606321200  0.305
2007 Saito Y, Sano Y, Nakaya T, Itohara S, Suzuki T. The roles of X11 and X11L in APP metabolism Neuroscience Research. 58: S117. DOI: 10.1016/J.Neures.2007.06.1251  0.627
2007 Sano Y, Boulay C, Suzuki T, Murphy N, Itohara S. A possible role for an adaptor protein, X11L/mint2, in risk assessment Neuroscience Research. 58: S107. DOI: 10.1016/J.Neures.2007.06.1192  0.615
2006 Sano Y, Nakaya T, Pedrini S, Takeda S, Iijima-Ando K, Iijima K, Mathews PM, Itohara S, Gandy S, Suzuki T. Physiological mouse brain Abeta levels are not related to the phosphorylation state of threonine-668 of Alzheimer's APP. Plos One. 1: e51. PMID 17183681 DOI: 10.1371/Journal.Pone.0000051  0.692
2006 Sumioka A, Yamamoto T, Suzuki T. [Novel mechanisms in signal transduction and cellular response through neural adaptor proteins]. Seikagaku. the Journal of Japanese Biochemical Society. 78: 949-56. PMID 17131878  0.771
2006 Sano Y, Syuzo-Takabatake A, Nakaya T, Saito Y, Tomita S, Itohara S, Suzuki T. Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. The Journal of Biological Chemistry. 281: 37853-60. PMID 17032642 DOI: 10.1074/Jbc.M609312200  0.775
2006 Suzuki T, Araki Y, Yamamoto T, Nakaya T. Trafficking of Alzheimer's disease-related membrane proteins and its participation in disease pathogenesis. Journal of Biochemistry. 139: 949-55. PMID 16788045 DOI: 10.1093/Jb/Mvj121  0.631
2006 Nakaya T, Suzuki T. Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 11: 633-45. PMID 16716194 DOI: 10.1111/J.1365-2443.2006.00968.X  0.355
2006 Feniouk BA, Suzuki T, Yoshida M. The role of subunit epsilon in the catalysis and regulation of FOF1-ATP synthase. Biochimica Et Biophysica Acta. 1757: 326-38. PMID 16701076 DOI: 10.1016/J.Bbabio.2006.03.022  0.306
2006 Masaike T, Suzuki T, Tsunoda SP, Konno H, Yoshida M. Probing conformations of the beta subunit of F0F1-ATP synthase in catalysis. Biochemical and Biophysical Research Communications. 342: 800-7. PMID 16517239 DOI: 10.1016/J.Bbrc.2006.02.017  0.315
2006 Saito Y, Zhu G, Sano Y, Okada M, Nakaya T, Kaneko S, Itohara S, Suzuki T. P2-010: Analysis of X11/X11L gene deficient mice Alzheimer's & Dementia. 2: S234-S235. DOI: 10.1016/J.Jalz.2006.05.847  0.495
2006 Kawano T, Araki Y, Nakaya T, Matsuno K, Suzuki T. P1-376 Alzheimer's & Dementia. 2: S208. DOI: 10.1016/J.Jalz.2006.05.754  0.517
2006 Suzuki T, Sano Y, Itohara S, Nakaya T. P1-060: APP metabolism in the brain of X11-like null mutant mouse Alzheimer's & Dementia. 2: S112-S112. DOI: 10.1016/J.Jalz.2006.05.435  0.648
2006 Araki Y, Suzuki T. P4-042: Alcadein, a presenilin/ γ-secretase substrate is a novel cargo receptor for kinesin-I Alzheimer's & Dementia. 2: S525-S526. DOI: 10.1016/J.Jalz.2006.05.1780  0.537
2006 Hoshino T, Nakaya T, Suzuki T, Mizushima T. P4-029: Inhibition of amyloid-B production by endoplasmic reticulum chaperones Alzheimer's & Dementia. 2: S521-S522. DOI: 10.1016/J.Jalz.2006.05.1767  0.325
2006 Hata S, Araki Y, Akatsu H, Urakami K, Nishimura M, Nakaya T, Suzuki T. P4-020: β-Alc, metabolic products of alcadein, as a novel diagnostic marker in CSF of Alzheimer's disease Alzheimer's & Dementia. 2: S519-S519. DOI: 10.1016/J.Jalz.2006.05.1758  0.555
2006 Sakuma M, Taru H, Tanaka E, Nakaya T, Suzuki T. P4-015: Hyperosmotic stress enhances the interaction between APP and X11L Alzheimer's & Dementia. 2: S518-S518. DOI: 10.1016/J.Jalz.2006.05.1753  0.706
2006 Mizumaru C, Kihara A, Suzuki T. P4-012: Molecular mechanism of DHHC family proteins on the suppression of Aβ generation Alzheimer's & Dementia. 2: S517-S517. DOI: 10.1016/J.Jalz.2006.05.1750  0.356
2005 Sumioka A, Nagaishi S, Yoshida T, Lin A, Miura M, Suzuki T. Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment. The Journal of Biological Chemistry. 280: 42364-74. PMID 16223726 DOI: 10.1074/Jbc.M504278200  0.778
2005 Asaumi M, Iijima K, Sumioka A, Iijima-Ando K, Kirino Y, Nakaya T, Suzuki T. Interaction of N-terminal acetyltransferase with the cytoplasmic domain of beta-amyloid precursor protein and its effect on A beta secretion. Journal of Biochemistry. 137: 147-55. PMID 15749829 DOI: 10.1093/Jb/Mvi014  0.822
2004 von Rotz RC, Kohli BM, Bosset J, Meier M, Suzuki T, Nitsch RM, Konietzko U. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. Journal of Cell Science. 117: 4435-48. PMID 15331662 DOI: 10.1242/Jcs.01323  0.444
2004 Taru H, Yoshikawa K, Suzuki T. Suppression of the caspase cleavage of beta-amyloid precursor protein by its cytoplasmic phosphorylation. Febs Letters. 567: 248-52. PMID 15178331 DOI: 10.1016/J.Febslet.2004.04.077  0.767
2004 Tabuchi A, Ishii A, Fukuchi M, Kobayashi S, Suzuki T, Tsuda M. Activity-dependent increase in beta-amyloid precursor protein mRNA expression in neurons. Neuroreport. 15: 1329-33. PMID 15167560 DOI: 10.1097/01.Wnr.0000127140.54853.04  0.369
2004 Araki Y, Miyagi N, Kato N, Yoshida T, Wada S, Nishimura M, Komano H, Yamamoto T, De Strooper B, Yamamoto K, Suzuki T. Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. The Journal of Biological Chemistry. 279: 24343-54. PMID 15037614 DOI: 10.1074/Jbc.M401925200  0.658
2004 Taru H, Suzuki T. Facilitation of stress-induced phosphorylation of beta-amyloid precursor protein family members by X11-like/Mint2 protein. The Journal of Biological Chemistry. 279: 21628-36. PMID 14970211 DOI: 10.1074/Jbc.M312007200  0.782
2004 Sawamura N, Ko M, Yu W, Zou K, Hanada K, Suzuki T, Gong JS, Yanagisawa K, Michikawa M. Modulation of amyloid precursor protein cleavage by cellular sphingolipids. The Journal of Biological Chemistry. 279: 11984-91. PMID 14715666 DOI: 10.1074/Jbc.M309832200  0.409
2004 Araki Y, Miyagi N, Kato N, Yoshida T, Suzuki T. P4-299 Presenilin-dependent gamma-secretase cleavage of alcadein and amyloid precursor protein: their coordinative metabolism and cooperative regulation on FE65-dependent gene transactivation Neurobiology of Aging. 25: S560. DOI: 10.1016/S0197-4580(04)81857-8  0.623
2004 Nakaya T, Kawaguchi E, Suzuki T. P1-285 Phosphorylation of APP at THR668 regulates the function of APP intracellular domain fragment Neurobiology of Aging. 25: S177. DOI: 10.1016/S0197-4580(04)80598-0  0.395
2004 Sumioka A, Miura M, Suzuki T. P1-282 14-3-3 modulates gene transactivation of AICD through it's interaction between C-terminal region of APP Neurobiology of Aging. 25: S176. DOI: 10.1016/S0197-4580(04)80595-5  0.782
2004 Taru H, Suzuki T. P1-229 Stress-induced phosphorylation of beta-amyloid precursor protein by JNK and its facilitation by X11-like/mint2 protein Neurobiology of Aging. 25: S161. DOI: 10.1016/S0197-4580(04)80542-6  0.76
2004 Miyagi N, Sakuma M, Araki Y, Suzuki T. P1-225 X11L and Alcadein form a tripartite comprex with APP and suppress the γ-cleavage of CTFβ Neurobiology of Aging. 25: S160. DOI: 10.1016/S0197-4580(04)80538-4  0.568
2003 Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T. Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. The Journal of Biological Chemistry. 278: 49448-58. PMID 12972431 DOI: 10.1074/Jbc.M306024200  0.82
2003 Sumioka A, Imoto S, Martins RN, Kirino Y, Suzuki T. XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanisms. The Biochemical Journal. 374: 261-8. PMID 12780348 DOI: 10.1042/Bj20030489  0.836
2003 Inomata H, Nakamura Y, Hayakawa A, Takata H, Suzuki T, Miyazawa K, Kitamura N. A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. The Journal of Biological Chemistry. 278: 22946-55. PMID 12665528 DOI: 10.1074/Jbc.M212160200  0.422
2002 Ishii J, Adachi H, Aoki J, Koizumi H, Tomita S, Suzuki T, Tsujimoto M, Inoue K, Arai H. SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain. The Journal of Biological Chemistry. 277: 39696-702. PMID 12154095 DOI: 10.1074/Jbc.M206140200  0.604
2002 Hase M, Yagi Y, Taru H, Tomita S, Sumioka A, Hori K, Miyamoto K, Sasamura T, Nakamura M, Matsuno K, Suzuki T. Expression and characterization of the Drosophila X11-like/Mint protein during neural development. Journal of Neurochemistry. 81: 1223-32. PMID 12068070 DOI: 10.1046/J.1471-4159.2002.00911.X  0.807
2002 Taru H, Kirino Y, Suzuki T. Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism. The Journal of Biological Chemistry. 277: 27567-74. PMID 12023290 DOI: 10.1074/Jbc.M203713200  0.78
2002 Taru H, Iijima K, Hase M, Kirino Y, Yagi Y, Suzuki T. Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. The Journal of Biological Chemistry. 277: 20070-8. PMID 11912189 DOI: 10.1074/Jbc.M108372200  0.78
2002 Sai X, Kawamura Y, Kokame K, Yamaguchi H, Shiraishi H, Suzuki R, Suzuki T, Kawaichi M, Miyata T, Kitamura T, De Strooper B, Yanagisawa K, Komano H. Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. The Journal of Biological Chemistry. 277: 12915-20. PMID 11799129 DOI: 10.1074/Jbc.M112372200  0.471
2001 Ando K, Iijima KI, Elliott JI, Kirino Y, Suzuki T. Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid. The Journal of Biological Chemistry. 276: 40353-61. PMID 11517218 DOI: 10.1074/Jbc.M104059200  0.436
2001 Satoh Y, Hirakura Y, Shibayama S, Hirashima N, Suzuki T, Kirino Y. Beta-amyloid peptides inhibit acetylcholine release from cholinergic presynaptic nerve endings isolated from an electric ray. Neuroscience Letters. 302: 97-100. PMID 11290396 DOI: 10.1016/S0304-3940(01)01665-2  0.33
2000 Suzuki T, Ando K, Iijima K, Oguchi S, Takeda S. Phosphorylation of Amyloid Precursor Protein (APP) Family Proteins. Methods in Molecular Medicine. 32: 271-82. PMID 21318525 DOI: 10.1385/1-59259-195-7:271  0.457
2000 Yagi Y, Tomita S, Nakamura M, Suzuki T. Overexpression of human amyloid precursor protein in Drosophila. Molecular Cell Biology Research Communications : McBrc. 4: 43-9. PMID 11152627 DOI: 10.1006/Mcbr.2000.0248  0.696
2000 Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, Greengard P, Kirino Y, Nairn AC, Suzuki T. Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. Journal of Neurochemistry. 75: 1085-91. PMID 10936190 DOI: 10.1046/J.1471-4159.2000.0751085.X  0.709
2000 Lee DS, Tomita S, Kirino Y, Suzuki T. Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein. The Journal of Biological Chemistry. 275: 23134-8. PMID 10833507 DOI: 10.1074/Jbc.C000302200  0.711
2000 Tomita S, Fujita T, Kirino Y, Suzuki T. PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein. The Journal of Biological Chemistry. 275: 13056-60. PMID 10777610 DOI: 10.1074/Jbc.C000019200  0.681
2000 Taru H, Yagi Y, Hase M, Tomita S, Kirino Y, Suzuki T. Isolation and characterization of a cDNA encoding a novel drosophila APPL binding protein Neurobiology of Aging. 21: 256. DOI: 10.1016/S0197-4580(00)83102-4  0.781
2000 Lee D, Tomita S, Takeda S, Martins R, Suzuki T. Isolation of CDNA encoding a novel protein that associates with neuron-specific X11L protein Neurobiology of Aging. 21: 23. DOI: 10.1016/S0197-4580(00)82781-5  0.63
2000 Iijima K, Ando K, Kirino Y, Suzuki T. Isolation and characterization of a novel APP binding protein Neurobiology of Aging. 21: 186. DOI: 10.1016/S0197-4580(00)82175-2  0.364
2000 Ando K, Iijima K, Kirino Y, Suzuki T. Novel regulation of interaction between APP and its binding proteins Neurobiology of Aging. 21: 185. DOI: 10.1016/S0197-4580(00)82173-9  0.389
1999 Isohara T, Horiuchi A, Watanabe T, Ando K, Czernik AJ, Uno I, Greengard P, Nairn AC, Suzuki T. Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase. Biochemical and Biophysical Research Communications. 258: 300-5. PMID 10329382 DOI: 10.1006/Bbrc.1999.0637  0.639
1999 Watanabe T, Sukegawa J, Sukegawa I, Tomita S, Iijima K, Oguchi S, Suzuki T, Nairn AC, Greengard P. A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein. Journal of Neurochemistry. 72: 549-56. PMID 9930726 DOI: 10.1046/J.1471-4159.1999.0720549.X  0.78
1999 Tomita S, Ozaki T, Taru H, Oguchi S, Takeda S, Yagi Y, Sakiyama S, Kirino Y, Suzuki T. Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein. The Journal of Biological Chemistry. 274: 2243-54. PMID 9890987 DOI: 10.1074/Jbc.274.4.2243  0.815
1999 Ando K, Oishi M, Takeda S, Iijima K, Isohara T, Nairn AC, Kirino Y, Greengard P, Suzuki T. Role of Phosphorylation of Alzheimer’s Amyloid Precursor Protein during Neuronal Differentiation The Journal of Neuroscience. 19: 4421-4427. DOI: 10.1523/Jneurosci.19-11-04421.1999  0.633
1998 Hirakura Y, Satoh Y, Hirashima N, Suzuki T, Kagan BL, Kirino Y. Membrane perturbation by the neurotoxic Alzheimer amyloid fragment beta 25-35 requires aggregation and beta-sheet formation. Biochemistry and Molecular Biology International. 46: 787-94. PMID 9844740 DOI: 10.1080/15216549800204332  0.349
1998 Tomita S, Kirino Y, Suzuki T. A basic amino acid in the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein (APP) is essential for cleavage of APP at the alpha-site. The Journal of Biological Chemistry. 273: 19304-10. PMID 9668120 DOI: 10.1074/Jbc.273.30.19304  0.685
1998 Tomita S, Kirino Y, Suzuki T. Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism. The Journal of Biological Chemistry. 273: 6277-84. PMID 9497354 DOI: 10.1074/Jbc.273.11.6277  0.692
1998 Iijima K, Lee DS, Okutsu J, Tomita S, Hirashima N, Kirino Y, Suzuki T. cDNA isolation of Alzheimer's amyloid precursor protein from cholinergic nerve terminals of the electric organ of the electric ray. The Biochemical Journal. 330: 29-33. PMID 9461486 DOI: 10.1042/Bj3300029  0.67
1997 Itoh T, Ikeda T, Gomi H, Nakao S, Suzuki T, Itohara S. Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice. The Journal of Biological Chemistry. 272: 22389-92. PMID 9278386 DOI: 10.1074/Jbc.272.36.22389  0.592
1997 Suzuki T, Ando K, Isohara T, Oishi M, Lim GS, Satoh Y, Wasco W, Tanzi RE, Nairn AC, Greengard P, Gandy SE, Kirino Y. Phosphorylation of Alzheimer beta-amyloid precursor-like proteins. Biochemistry. 36: 4643-9. PMID 9109675 DOI: 10.1021/Bi962618K  0.636
1997 Oishi M, Nairn AC, Czernik AJ, Lim GS, Isohara T, Gandy SE, Greengard P, Suzuki T. The Cytoplasmic Domain of Alzheimer’s Amyloid Precursor Protein Is Phosphorylated at Thr654, Ser655, and Thr668 in Adult Rat Brain and Cultured Cells Molecular Medicine. 3: 111-123. DOI: 10.1007/Bf03401803  0.616
1996 Tomita S, Kirino Y, Suzuki T. 391 Possible functions of the sites covalently modified of APP in APP metabolism Neurobiology of Aging. 17: S98. DOI: 10.1016/S0197-4580(96)80393-9  0.311
1996 Watanabe T, Suzuki T, Sukegawa J, Sukegawa I, Nairn A, Greengard P. 387 Identification of a protein which interacts with the cytoplasmic domain of the Alzheimer amyloid protein Precursor Neurobiology of Aging. 17: S97. DOI: 10.1016/S0197-4580(96)80389-7  0.668
1996 Suzuki T, Kitao S, Matsushime H, Yoshida M. HTLV‐1 Tax protein interacts with cyclin‐dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4. The Embo Journal. 15: 1607-1614. DOI: 10.1002/J.1460-2075.1996.Tb00505.X  0.339
1995 Fukuda I, Suzuki T, Munakata H, Hayashi N, Katayama E, Yoshikawa M, Sasakawa C. Cleavage of Shigella surface protein VirG occurs at a specific site, but the secretion is not essential for intracellular spreading. Journal of Bacteriology. 177: 1719-1726. PMID 7896693 DOI: 10.1128/Jb.177.7.1719-1726.1995  0.342
1994 Oishi M, Lim GS, Isohara T, Watanabe T, Qu Z, Horiuchi A, Marshak DR, Czernik AJ, Nairn AC, Greengard P, Suzuki T. Regulated Phosphorylation of App in-Vivo Neurobiology of Aging. 15. DOI: 10.1016/0197-4580(94)92796-0  0.513
1994 Suzuki T, Oishi M, Marshak D, Czernik A, Nairn A, Greengard P. Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. The Embo Journal. 13: 1114-1122. DOI: 10.1002/J.1460-2075.1994.Tb06360.X  0.678
1993 Li L, Suzuki T, Mori N, Greengard P. Identification of a functional silencer element involved in neuron-specific expression of the synapsin I gene. Proceedings of the National Academy of Sciences of the United States of America. 90: 1460-4. PMID 8381968 DOI: 10.1073/Pnas.90.4.1460  0.473
1992 Suzuki T, Nairn AC, Gandy SE, Greengard P. Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C. Neuroscience. 48: 755-61. PMID 1630623 DOI: 10.1016/0306-4522(92)90264-3  0.644
1992 Gandy SE, Buxbaum JD, Suzuki T, Ramabhadran TV, Caporaso GL, Nairn AC, Greengard P. The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes. Neurobiology of Aging. 13: 601-3. PMID 1461349 DOI: 10.1016/0197-4580(92)90063-4  0.718
1992 Nakata N, Sasakawa C, Okada N, Tobe T, Fukuda I, Suzuki T, Komatsu K, Yoshikawa M. Identification and characterization of virK, a virulence-associated large plasmid gene essential for intercellular spreading of Shigella flexneri. Molecular Microbiology. 6: 2387-2395. PMID 1406277 DOI: 10.1111/J.1365-2958.1992.Tb01413.X  0.323
1992 Gandy SE, Caporaso GL, Ramabhadran TV, Suzuki T, Buxbaum JD, Nordstedt C, Iverfeldt K, Czernik AJ, Nairn AC, Greengard P. Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine. Annals of the New York Academy of Sciences. 674: 203-17. PMID 1363189 DOI: 10.1111/J.1749-6632.1992.Tb27489.X  0.691
1983 Suzuki T, Natori S. Identification of a protein having hemagglutinating activity in the hemolymph of the silkworm, Bombyx mori. Journal of Biochemistry. 93: 583-590. PMID 6404903 DOI: 10.1093/Oxfordjournals.Jbchem.A134213  0.32
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